Hspb3 (heat shock protein family B (small) member 3) - Rat Genome Database

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Gene: Hspb3 (heat shock protein family B (small) member 3) Rattus norvegicus
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Symbol: Hspb3
Name: heat shock protein family B (small) member 3
RGD ID: 68345
Description: Predicted to be located in nucleus. Predicted to be active in cytoplasm and nuclear speck. Human ortholog(s) of this gene implicated in autosomal dominant distal hereditary motor neuronopathy 4. Orthologous to human HSPB3 (heat shock protein family B (small) member 3); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: heat shock 27kD protein 3; heat shock 27kD protein family, member 3; heat shock 27kDa protein 3; heat shock protein 3; heat shock protein B3; heat shock protein beta-3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8247,028,451 - 47,029,165 (-)NCBIGRCr8
mRatBN7.2245,295,285 - 45,295,999 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl245,295,053 - 45,296,145 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx252,406,949 - 52,407,663 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0250,465,318 - 50,466,032 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0245,338,460 - 45,339,174 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0245,517,788 - 45,518,502 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl245,517,789 - 45,518,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0264,549,281 - 64,549,995 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,078,615 - 45,079,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1245,006,847 - 45,007,562 (-)NCBI
Celera241,063,625 - 41,064,339 (-)NCBICelera
Cytogenetic Map2q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO,ISS)
nuclear speck  (IBA,IEA,ISO)
nucleus  (ISO,ISS)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:10625651   PMID:19464326   PMID:19715703  


Genomics

Comparative Map Data
Hspb3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8247,028,451 - 47,029,165 (-)NCBIGRCr8
mRatBN7.2245,295,285 - 45,295,999 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl245,295,053 - 45,296,145 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx252,406,949 - 52,407,663 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0250,465,318 - 50,466,032 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0245,338,460 - 45,339,174 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0245,517,788 - 45,518,502 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl245,517,789 - 45,518,502 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0264,549,281 - 64,549,995 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4245,078,615 - 45,079,329 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1245,006,847 - 45,007,562 (-)NCBI
Celera241,063,625 - 41,064,339 (-)NCBICelera
Cytogenetic Map2q14NCBI
HSPB3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38554,455,699 - 54,456,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl554,455,699 - 54,456,377 (+)EnsemblGRCh38hg38GRCh38
GRCh37553,751,529 - 53,752,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36553,787,202 - 53,787,964 (+)NCBINCBI36Build 36hg18NCBI36
Build 34553,787,201 - 53,787,964NCBI
Celera550,705,068 - 50,705,830 (+)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef550,725,404 - 50,726,187 (+)NCBIHuRef
CHM1_1553,754,285 - 53,755,068 (+)NCBICHM1_1
T2T-CHM13v2.0555,283,264 - 55,283,942 (+)NCBIT2T-CHM13v2.0
Hspb3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,799,432 - 113,800,212 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,799,432 - 113,800,212 (-)EnsemblGRCm39 Ensembl
GRCm3813113,662,896 - 113,663,676 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13113,662,896 - 113,663,676 (-)EnsemblGRCm38mm10GRCm38
MGSCv3713114,453,104 - 114,453,884 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,783,774 - 114,784,537 (-)NCBIMGSCv36mm8
Celera13117,987,638 - 117,988,418 (-)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1364.01NCBI
Hspb3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544613,113,984 - 13,114,442 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544613,113,854 - 13,114,599 (-)NCBIChiLan1.0ChiLan1.0
HSPB3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2459,480,184 - 59,480,962 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1557,631,048 - 57,634,586 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0559,566,129 - 59,569,668 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1561,190,450 - 61,191,220 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl561,190,585 - 61,191,037 (-)Ensemblpanpan1.1panPan2
HSPB3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1460,953,530 - 61,001,912 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl460,985,195 - 60,985,647 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha460,720,671 - 60,825,699 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0461,446,367 - 61,551,465 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1461,225,186 - 61,330,105 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0461,352,336 - 61,426,819 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0461,871,138 - 61,976,297 (-)NCBIUU_Cfam_GSD_1.0
Hspb3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213204,240,935 - 204,242,322 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648013,178,022 - 13,178,480 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648013,177,430 - 13,178,824 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HSPB3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1633,716,626 - 33,719,018 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11633,716,458 - 33,717,402 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21635,787,723 - 35,788,802 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HSPB3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1450,732,737 - 50,733,744 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl450,733,157 - 50,733,609 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666082343,576 - 347,073 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hspb3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,933,197 - 4,933,655 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,933,086 - 4,933,828 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:104
Interacting mature miRNAs:104
Transcripts:ENSRNOT00000014627
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10755430Coatc6Coat color QTL 60.02576coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)21332504158325041Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23675034481750344Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
9590080Insglur4Insulin/glucose ratio QTL 428.70.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)2615276751152767Rat
1300160Hrtrt3Heart rate QTL 33.62heart pumping trait (VT:2000009)absolute change in heart rate (CMO:0000534)23561408353462005Rat
1579916Bp270Blood pressure QTL 2700.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21605188361051883Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22203804467038044Rat
731166Mamtr2Mammary tumor resistance QTL 20.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)2962358154623581Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22888999173889991Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)241801363104744824Rat
1331764Bp205Blood pressure QTL 2053.476arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)21436870759368707Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24490435585286097Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1300155Bp174Blood pressure QTL 1744.09arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)244537979112567334Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)27605533104774005Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266683465677Rat
1578664Bmd9Bone mineral QTL density 95femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)2573632550736325Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)238426449111295694Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21822713763227137Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23686864381868643Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)24490435589904355Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)23326999678269996Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22865266673652666Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 68 48 48 25 17 25 6 163 82 55 39 52 23

Sequence


Ensembl Acc Id: ENSRNOT00000014627   ⟹   ENSRNOP00000014627
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl245,295,053 - 45,296,145 (-)Ensembl
Rnor_6.0 Ensembl245,517,789 - 45,518,502 (-)Ensembl
RefSeq Acc Id: NM_031750   ⟹   NP_113938
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8247,028,451 - 47,029,165 (-)NCBI
mRatBN7.2245,295,285 - 45,295,999 (-)NCBI
Rnor_6.0245,517,788 - 45,518,502 (-)NCBI
Rnor_5.0264,549,281 - 64,549,995 (-)NCBI
RGSC_v3.4245,078,615 - 45,079,329 (-)RGD
Celera241,063,625 - 41,064,339 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113938 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAF09588 (Get FASTA)   NCBI Sequence Viewer  
  EDM10375 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014627.1
GenBank Protein Q9QZ58 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113938   ⟸   NM_031750
- UniProtKB: Q9QZ58 (UniProtKB/Swiss-Prot),   A6I5R7 (UniProtKB/TrEMBL),   G3V7G6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014627   ⟸   ENSRNOT00000014627
Protein Domains
sHSP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZ58-F1-model_v2 AlphaFold Q9QZ58 1-152 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:68345 AgrOrtholog
BioCyc Gene G2FUF-54351 BioCyc
Ensembl Genes ENSRNOG00000010992 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014627.4 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.790 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A-crystallin/Hsp20_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Alpha-crystallin/HSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSP20-like_chaperone UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HSPB3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:78951 UniProtKB/Swiss-Prot
NCBI Gene 78951 ENTREZGENE
PANTHER HEAT SHOCK PROTEIN BETA-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR47097 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam HSP20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hspb3 PhenoGen
PRINTS ACRYSTALLIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE SHSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010992 RatGTEx
Superfamily-SCOP SSF49764 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC219396
UniProt A6I5R7 ENTREZGENE, UniProtKB/TrEMBL
  G3V7G6 ENTREZGENE, UniProtKB/TrEMBL
  HSPB3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-02 Hspb3  heat shock protein family B (small) member 3  Hspb3  heat shock protein B3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-01-23 Hspb3  heat shock protein B3  Hspb3  heat shock protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Hspb3  heat shock protein 3  Hspb3  heat shock 27kDa protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Hspb3  heat shock 27kDa protein 3    heat shock 27kD protein family, member 3  Name updated 1299863 APPROVED
2002-06-10 Hspb3  heat shock 27kD protein family, member 3      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference