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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cannabinoid
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Accession:CHEBI:67194 term browser browse the term
Definition:A diverse group of pharmacologically active secondary metabolite characteristic to Cannabis plant as well as produced naturally in the body by humans and animals. Cannabinoids contain oxygen as a part of the heterocyclic ring or in the form of various functional groups. They are subdivided on the basis of their origin.
Synonyms:related_synonym: cannabinoids
 xref: PMID:22234284;   PMID:22530636;   PMID:22555283;   Wikipedia:Cannabinoid


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11-hydroxy-Delta(9)-tetrahydrocannabinol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fabp1 fatty acid binding protein 1 multiple interactions ISO
EXP
[FABP1 protein affects the transport of Dronabinol] which affects the abundance of 11-hydroxy-delta(9)-tetrahydrocannabinol
11-hydroxy-delta(9)-tetrahydrocannabinol affects the folding of and results in increased stability of FABP1 protein; 11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [anandamide analog binds to FABP1 protein]
11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein]
CTD PMID:30232874 PMID:31110286 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions EXP 11-hydroxy-delta(9)-tetrahydrocannabinol binds to and results in increased activity of TRPV2 protein CTD PMID:18550765 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030
JBrowse link
2-arachidonoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase increases hydrolysis ISO ABHD12 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr 3:146,630,298...146,690,375
Ensembl chr 3:146,630,299...146,690,375
JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase increases hydrolysis ISO ABHD6 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr15:18,647,903...18,695,133
Ensembl chr15:18,647,844...18,695,133
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
EXP glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA]
CTD PMID:21863215 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
ISO glyceryl 2-arachidonate results in increased expression of ATF4 mRNA
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of ATF4 mRNA]
CTD PMID:32357311 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of BTG2 mRNA CTD PMID:28095641 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of CCL2 protein CTD PMID:15115777 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis
multiple interactions
ISO CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid
CTD PMID:21049984 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis
multiple interactions
ISO CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid
CTD PMID:21049984 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression
ISO
EXP
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate results in increased expression of CNR1 mRNA
[GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]]
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of CNR1 mRNA]; Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein]
CTD PMID:12657697 PMID:15899896 PMID:16775503 PMID:21863215 PMID:23894352 PMID:26209559 PMID:28095641 PMID:31024316 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects response to substance
ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]
CNR2 gene SNP affects the susceptibility to glyceryl 2-arachidonate
CTD PMID:10617657 PMID:15115777 PMID:20124950 PMID:31024316 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
increases expression
ISO glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA] CTD PMID:23894352 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Crh corticotropin releasing hormone increases abundance ISO CRH protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:26821211 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 9:81,968,285...81,998,213
Ensembl chr 9:81,968,332...81,998,169
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 multiple interactions
increases expression
ISO CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 increases expression
multiple interactions
ISO glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]
CTD PMID:23894352 NCBI chr 2:102,701,903...102,871,257
Ensembl chr 2:102,701,903...102,871,257
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression
multiple interactions
ISO glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]
CTD PMID:23894352 PMID:28095641 NCBI chr 8:130,548,418...130,550,388
Ensembl chr 8:130,548,418...130,550,388
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA; glyceryl 2-arachidonate results in increased expression of DDIT3 protein
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 protein]
CTD PMID:32357311 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions
increases phosphorylation
ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein] CTD PMID:32357311 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Esrrg estrogen-related receptor gamma increases abundance ISO ESRRG protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:31912162 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Fmr1 FMRP translational regulator 1 multiple interactions ISO [FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate CTD PMID:20393458 NCBI chr  X:154,684,924...154,722,369
Ensembl chr  X:154,684,935...154,722,314
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions EXP FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:12657697 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO glyceryl 2-arachidonate results in increased expression of HSPA5 mRNA CTD PMID:32357311 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO glyceryl 2-arachidonate results in decreased expression of IL1B mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]
CTD PMID:16364651 PMID:30611738 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]] CTD PMID:21511917 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
ISO glyceryl 2-arachidonate results in decreased expression of IL6 mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]
CTD PMID:16364651 PMID:30611738 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:12657697 PMID:31917333 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO
EXP
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:12657697 PMID:31917333 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mgll monoglyceride lipase multiple interactions
affects abundance
increases degradation
increases abundance
increases hydrolysis
EXP
ISO
[Chlorpyrifos results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; JZL 184 inhibits the reaction [MGLL protein results in increased hydrolysis of glyceryl 2-arachidonate]
MGLL protein affects the abundance of glyceryl 2-arachidonate
MGLL protein results in increased degradation of glyceryl 2-arachidonate
[FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate; [JZL 184 results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate
MGLL gene mutant form results in increased abundance of glyceryl 2-arachidonate
CTD PMID:18096503 PMID:20393458 PMID:21507991 PMID:23761300 PMID:25030704 PMID:26209559 PMID:26642910 PMID:30301768 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:30611738 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] CTD PMID:32357311 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects localization
multiple interactions
EXP glyceryl 2-arachidonate affects the localization of PPARA protein
[palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]; glyceryl 2-arachidonate affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]
CTD PMID:31787870 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding
multiple interactions
increases expression
ISO glyceryl 2-arachidonate metabolite binds to PPARG protein
glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]
T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite results in increased expression of PPARG mRNA]
CTD PMID:21511917 PMID:26209559 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions EXP [Indomethacin results in decreased expression of PTGS1] which results in increased activity of glyceryl 2-arachidonate CTD PMID:17245358 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing
multiple interactions
ISO PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate]
CTD PMID:18297109 PMID:21511917 PMID:26209559 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
ISO
EXP
glyceryl 2-arachidonate results in decreased expression of TNF mRNA
glyceryl 2-arachidonate inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; glyceryl 2-arachidonate inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]
glyceryl 2-arachidonate inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
CTD PMID:12509806 PMID:16364651 PMID:30611738 PMID:30769029 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
affects response to substance
EXP
ISO
glyceryl 2-arachidonate binds to and results in increased activity of TRPV1 protein
TRPV1 protein affects the susceptibility to glyceryl 2-arachidonate
CTD PMID:18550765 PMID:21949157 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Yy1 YY1 transcription factor increases expression ISO glyceryl 2-arachidonate results in increased expression of YY1 mRNA CTD PMID:28095641 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
anandamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
decreases expression
ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; iodopravadoline inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]
anandamide results in decreased expression of ABCG2 mRNA; anandamide results in decreased expression of ABCG2 protein
CTD PMID:30610963 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G App amyloid beta precursor protein decreases response to substance
decreases metabolic processing
decreases abundance
EXP
ISO
anandamide results in decreased susceptibility to APP protein
APP protein results in decreased metabolism of anandamide
APP protein results in decreased abundance of anandamide
CTD PMID:22233683 PMID:26976670 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Bdkrb1 bradykinin receptor B1 multiple interactions
decreases activity
ISO AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] CTD PMID:19022239 NCBI chr 6:129,437,423...129,441,553
Ensembl chr 6:129,438,158...129,440,574
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO anandamide results in increased cleavage of CASP3 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased cleavage of CASP3 protein]
CTD PMID:26513129 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cd36 CD36 molecule increases expression ISO anandamide results in increased expression of CD36 mRNA; anandamide results in increased expression of CD36 protein CTD PMID:17360047 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cga glycoprotein hormones, alpha polypeptide decreases expression ISO anandamide results in decreased expression of CGA mRNA CTD PMID:30610963 NCBI chr 5:50,362,491...50,393,368
Ensembl chr 5:50,381,244...50,393,367
JBrowse link
G Cnr1 cannabinoid receptor 1 affects activity
decreases expression
affects binding
increases activity
multiple interactions
ISO
EXP
anandamide affects the activity of CNR1 protein
anandamide results in decreased expression of CNR1 protein
anandamide binds to CNR1 protein
anandamide results in increased activity of CNR1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased activity of CNR1]; anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Pertussis Toxin inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]
[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; SR 144528 inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]
CTD PMID:10871313 PMID:11408034 PMID:11891798 PMID:12657697 PMID:14504685 PMID:15453094 PMID:17557913 PMID:19147270 PMID:31024316 PMID:31199905 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 affects activity
affects binding
multiple interactions
ISO
EXP
anandamide affects the activity of CNR2 protein
anandamide binds to CNR2 protein
anandamide binds to and results in increased activity of CNR2 protein; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]
CTD PMID:10617657 PMID:10688601 PMID:15453094 PMID:19147270 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation
ISO anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
anandamide results in decreased phosphorylation of CREB1 protein
CTD PMID:30610963 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO anandamide results in increased expression of DDIT3 mRNA; anandamide results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]
CTD PMID:21949157 PMID:26513129 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
ISO anandamide results in increased phosphorylation of EIF2S1 protein
4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein]
CTD PMID:26513129 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Ervfrd-1 endogenous retrovirus group FRD member 1, envelope decreases expression ISO anandamide results in decreased expression of ERVFRD-1 mRNA CTD PMID:30610963 NCBI chr12:25,161,130...25,168,182
Ensembl chr12:25,161,130...25,168,182
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
increases expression
ISO anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein]
anandamide results in increased expression of F3 protein
CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Faah fatty acid amide hydrolase increases degradation
multiple interactions
affects expression
ISO
EXP
FAAH results in increased degradation of anandamide
FAAH protein results in increased degradation of anandamide
[Chlorpyrifos results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [Lipopolysaccharides results in decreased expression of FAAH protein] which results in increased abundance of anandamide; Nitroglycerin promotes the reaction [FAAH protein results in increased degradation of anandamide]
anandamide affects the expression of FAAH protein
[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]; [PF 3845 results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide
CTD PMID:11556820 PMID:16131814 PMID:16886060 PMID:19515121 PMID:20702753 PMID:23761300 PMID:26642910 PMID:31121907 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Faahl fatty-acid amide hydrolase-like increases degradation
affects expression
multiple interactions
ISO FAAH results in increased degradation of anandamide
anandamide affects the expression of FAAH protein
[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]; [PF 3845 results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide
CTD PMID:16131814 PMID:16886060 PMID:20702753 PMID:31121907 NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions
affects binding
EXP 11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [anandamide analog binds to FABP1 protein]; Dronabinol inhibits the reaction [anandamide analog binds to FABP1 protein] CTD PMID:30232874 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
EXP anandamide inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; capsazepine inhibits the reaction [anandamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [anandamide results in increased expression of FOS protein]
anandamide results in increased expression of FOS; anandamide results in increased expression of FOS protein
CTD PMID:9748483 PMID:15601931 PMID:19515121 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Ifng interferon gamma multiple interactions ISO anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]; anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B] CTD PMID:12813001 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO anandamide results in increased expression of IGF1 protein CTD PMID:17307377 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il12b interleukin 12B multiple interactions ISO [OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]; anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15748152 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]
anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B]; anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein]
CTD PMID:12813001 PMID:15748152 PMID:27556861 PMID:30611738 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]] CTD PMID:30611738 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lep leptin decreases abundance
decreases activity
decreases transport
ISO LEP protein results in decreased abundance of anandamide
LEP protein results in decreased activity of anandamide
LEP protein results in decreased transport of anandamide
CTD PMID:16154199 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
anandamide results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK1 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:12657697 PMID:19477951 PMID:21179406 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
anandamide results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK3 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:12657697 PMID:19477951 PMID:21179406 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO anandamide results in increased expression of MMP1 mRNA CTD PMID:16330497 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO anandamide results in increased expression of MMP3 mRNA CTD PMID:16330497 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of MMP9 mRNA] CTD PMID:16330497 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:11891798 PMID:15748152 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO anandamide binds to and results in increased activity of PPARA protein CTD PMID:17906680 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases metabolic processing
EXP
ISO
[nimesulide results in decreased expression of PTGS2] which results in increased activity of anandamide
anandamide results in increased expression of PTGS2 mRNA; anandamide results in increased expression of PTGS2 protein
PTGS2 results in increased metabolism of anandamide
[nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]
CTD PMID:16330497 PMID:17245358 PMID:20702753 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO anandamide results in increased expression of TIMP1 mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA]
CTD PMID:16330497 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
EXP
ISO
anandamide inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
anandamide inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]
TNF protein results in increased abundance of anandamide
anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]
CTD PMID:12509806 PMID:12813001 PMID:20626112 PMID:30611738 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases response to substance
increases activity
affects response to substance
affects binding
ISO
EXP
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Egtazic Acid inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; methyl arachidonylfluorophosphonate promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; N-(2-methyl-3-hydroxyphenyl)-5,8,11,14-eicosatetraenamide inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Nitroprusside promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Phenylmethylsulfonyl Fluoride promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]
TRPV1 protein results in increased susceptibility to anandamide
anandamide results in increased activity of TRPV1 protein
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; bisindolylmaleimide inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein]
anandamide binds to TRPV1 protein
CTD PMID:11140687 PMID:11278420 PMID:14504685 PMID:15453094 PMID:15601931 PMID:15615864 PMID:17038422 PMID:17913835 PMID:18550765 PMID:21949157 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO anandamide results in decreased expression of and results in decreased secretion of VEGFA protein CTD PMID:15313899 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
cannabidiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn1 actinin, alpha 1 affects methylation EXP Cannabidiol affects the methylation of ACTN1 gene CTD PMID:30521419 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Agtrap angiotensin II receptor-associated protein increases expression ISO Cannabidiol results in increased expression of AGTRAP mRNA CTD PMID:30742662 NCBI chr 5:164,888,069...164,898,387
Ensembl chr 5:164,886,813...164,898,420
JBrowse link
G Aicda activation-induced cytidine deaminase increases expression
multiple interactions
ISO Cannabidiol results in increased expression of AICDA mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of AICDA mRNA
CTD PMID:30742662 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 increases expression ISO Cannabidiol results in increased expression of AKR1B7 mRNA CTD PMID:21542829 NCBI chr 4:61,850,256...61,879,733
Ensembl chr 4:61,850,348...61,862,526
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO Cannabidiol results in decreased phosphorylation of AKT1 protein CTD PMID:28392768 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression ISO Cannabidiol results in increased expression of ANGPTL6 mRNA CTD PMID:21542829 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829
JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 affects methylation EXP Cannabidiol affects the methylation of APC2 gene CTD PMID:30521419 NCBI chr 7:12,258,468...12,280,459
Ensembl chr 7:12,258,468...12,275,609
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Cannabidiol inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA] CTD PMID:21350020 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 affects expression ISO Cannabidiol affects the expression of AQP4 mRNA CTD PMID:31054246 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Aqp9 aquaporin 9 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of AQP9 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of AQP9 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 8:77,559,621...77,599,781
Ensembl chr 8:77,559,624...77,599,781
JBrowse link
G Arpc1a actin related protein 2/3 complex, subunit 1A affects methylation EXP Cannabidiol affects the methylation of ARPC1A gene CTD PMID:30521419 NCBI chr12:11,272,609...11,294,084
Ensembl chr12:11,272,609...11,294,058
JBrowse link
G Arrb2 arrestin, beta 2 affects methylation EXP Cannabidiol affects the methylation of ARRB2 gene CTD PMID:30521419 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO Cannabidiol results in increased expression of ASB2 mRNA CTD PMID:27256343 NCBI chr 6:127,212,325...127,248,451
Ensembl chr 6:127,212,273...127,248,372
JBrowse link
G Atf3 activating transcription factor 3 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of ATF3 mRNA
Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of ATF3 mRNA]
CTD PMID:21542829 PMID:27256343 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Cannabidiol results in increased expression of ATF4 mRNA CTD PMID:21542829 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Cannabidiol results in increased expression of ATF5 mRNA CTD PMID:21542829 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Cannabidiol results in increased expression of ATP2A3 mRNA CTD PMID:21542829 NCBI chr10:59,528,849...59,560,440
Ensembl chr10:59,529,785...59,560,433
JBrowse link
G Avil advillin increases expression ISO Cannabidiol results in increased expression of AVIL mRNA CTD PMID:21542829 NCBI chr 7:70,292,565...70,310,588
Ensembl chr 7:70,292,565...70,310,588
JBrowse link
G Axin2 axin 2 affects methylation EXP Cannabidiol affects the methylation of AXIN2 gene CTD PMID:30521419 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Cannabidiol results in increased expression of AXL mRNA CTD PMID:30742662 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of BACH1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of BACH1 mRNA
CTD PMID:30742662 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Cannabidiol inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:27430346 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Cannabidiol results in increased expression of BDNF protein CTD PMID:19939866 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Bmp6 bone morphogenetic protein 6 affects methylation EXP Cannabidiol affects the methylation of BMP6 gene CTD PMID:30521419 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Bmp7 bone morphogenetic protein 7 affects methylation EXP Cannabidiol affects the methylation of BMP7 gene CTD PMID:30521419 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Btla B and T lymphocyte associated multiple interactions
increases expression
ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of BTLA mRNA]
Cannabidiol results in increased expression of BTLA mRNA
CTD PMID:27256343 NCBI chr11:60,523,692...60,547,234
Ensembl chr11:60,524,917...60,547,201
JBrowse link
G C1qa complement C1q A chain decreases expression ISO Cannabidiol results in decreased expression of C1QA mRNA CTD PMID:21542829 NCBI chr 5:155,261,254...155,264,101
Ensembl chr 5:155,261,250...155,264,143
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A affects methylation EXP Cannabidiol affects the methylation of CACNA1A gene CTD PMID:30521419 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G affects methylation EXP Cannabidiol affects the methylation of CACNA1G gene CTD PMID:30521419 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1i calcium voltage-gated channel subunit alpha1 I affects methylation EXP Cannabidiol affects the methylation of CACNA1I gene CTD PMID:30521419 NCBI chr 7:121,521,787...121,619,300
Ensembl chr 7:121,511,097...121,619,283
JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 affects methylation EXP Cannabidiol affects the methylation of CACNA2D1 gene CTD PMID:30521419 NCBI chr 4:15,706,974...16,130,848
Ensembl chr 4:15,710,417...16,130,848
JBrowse link
G Cacna2d2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 affects methylation EXP Cannabidiol affects the methylation of CACNA2D2 gene CTD PMID:30521419 NCBI chr 8:116,154,661...116,285,643
Ensembl chr 8:116,154,736...116,284,985
JBrowse link
G Cars cysteinyl-tRNA synthetase increases expression ISO Cannabidiol results in increased expression of CARS mRNA CTD PMID:21542829 NCBI chr 1:216,759,367...216,801,652
Ensembl chr 1:216,759,366...216,801,656
JBrowse link
G Casp3 caspase 3 multiple interactions
increases cleavage
ISO
EXP
[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein; [Cannabidiol co-treated with bafilomycin A1] results in increased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [[bafilomycin A1 co-treated with Cannabidiol] results in increased cleavage of CASP3 protein]; tin protoporphyrin IX inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA]
CTD PMID:27430346 PMID:32708634 PMID:32733202 PMID:33076330 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp4 caspase 4 increases expression ISO Cannabidiol results in increased expression of CASP4 mRNA CTD PMID:21542829 NCBI chr 8:2,616,391...2,651,682
Ensembl chr 8:2,635,851...2,651,652
JBrowse link
G Cat catalase decreases activity ISO Cannabidiol results in decreased activity of CAT protein CTD PMID:32752303 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CCL2 mRNA
Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL2 mRNA]
CTD PMID:19910459 PMID:21542829 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCL22 mRNA CTD PMID:30742662 NCBI chr19:10,674,189...10,681,145
Ensembl chr19:10,674,189...10,681,145
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 decreases expression ISO Cannabidiol results in decreased expression of CCL6 mRNA CTD PMID:21542829 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Cannabidiol results in decreased expression of CCL7 mRNA CTD PMID:21542829 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CCND1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCND1 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO Cannabidiol results in decreased expression of CCNE1 mRNA CTD PMID:21542829 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CCNE2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CCNE2 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cd274 CD274 molecule increases expression ISO Cannabidiol results in increased expression of CD274 mRNA CTD PMID:21542829 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd69 Cd69 molecule multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CD69 mRNA] CTD PMID:27256343 NCBI chr 4:163,041,147...163,049,065
Ensembl chr 4:163,041,141...163,049,084
JBrowse link
G Cdc25a cell division cycle 25A decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CDC25A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CDC25A mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Cannabidiol results in decreased expression of CDC6 mRNA CTD PMID:21542829 NCBI chr10:86,819,477...86,833,301
Ensembl chr10:86,819,472...86,833,402
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA] CTD PMID:32049991 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CDK5R1 mRNA] CTD PMID:27256343 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
ISO Cannabidiol results in increased expression of CDKN1A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CDKN1A mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
decreases expression
ISO
EXP
Cannabidiol results in increased expression of CDKN2A mRNA
Cannabidiol results in decreased expression of CDKN2A mRNA
CTD PMID:21542829 PMID:32553926 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression ISO Cannabidiol results in increased expression of CDKN2B mRNA CTD PMID:21542829 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CEBPB mRNA
Cannabidiol results in increased expression of CEBPB mRNA
CTD PMID:30742662 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO Cannabidiol results in increased expression of CFLAR mRNA CTD PMID:30742662 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chac1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 increases expression ISO Cannabidiol results in increased expression of CHAC1 mRNA CTD PMID:21542829 NCBI chr 3:111,160,205...111,163,425
Ensembl chr 3:111,160,205...111,163,425
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 increases expression ISO Cannabidiol results in increased expression of CHD2 mRNA CTD PMID:21542829 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Chrna2 cholinergic receptor nicotinic alpha 2 subunit decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of CHRNA2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CHRNA2 mRNA
CTD PMID:30742662 NCBI chr15:42,808,897...42,825,179
Ensembl chr15:42,808,897...42,825,179
JBrowse link
G Chst10 carbohydrate sulfotransferase 10 decreases expression ISO Cannabidiol results in decreased expression of CHST10 mRNA CTD PMID:21542829 NCBI chr 9:45,528,928...45,559,365
Ensembl chr 9:45,528,928...45,559,140
JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression ISO Cannabidiol results in increased expression of CISH mRNA CTD PMID:30742662 NCBI chr 8:116,054,547...116,059,494
Ensembl chr 8:116,054,465...116,060,723
JBrowse link
G Clec4e C-type lectin domain family 4, member E increases expression ISO Cannabidiol results in increased expression of CLEC4E mRNA CTD PMID:21542829 NCBI chr 4:156,271,087...156,276,243
Ensembl chr 4:156,270,920...156,276,304
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CMPK2 mRNA] CTD PMID:27256343 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
ISO
EXP
CNR1 polymorphism affects the susceptibility to [Dronabinol co-treated with Cannabidiol]; CNR1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
Cannabidiol inhibits the reaction [Poly I-C inhibits the reaction [Rimonabant binds to CNR1 protein]]
[1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene co-treated with CNR1 protein] affects the susceptibility to Cannabidiol
CNR1 protein affects the susceptibility to Cannabidiol
CTD PMID:20668920 PMID:30550613 PMID:31013550 PMID:31202911 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects expression
ISO CNR2 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
Cannabidiol affects the expression of CNR2 mRNA
CTD PMID:20668920 PMID:32733202 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression ISO Cannabidiol results in increased expression of COL4A1 mRNA CTD PMID:21542829 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Cannabidiol results in increased expression of COX6A2 mRNA CTD PMID:21542829 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Cpd carboxypeptidase D multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of CPD mRNA CTD PMID:30742662 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 increases expression ISO Cannabidiol results in increased expression of CPEB1 mRNA CTD PMID:21542829 NCBI chr 1:143,171,457...143,278,485
Ensembl chr 1:143,171,264...143,278,485
JBrowse link
G Crb1 crumbs cell polarity complex component 1 affects methylation EXP Cannabidiol affects the methylation of CRB1 gene CTD PMID:30521419 NCBI chr13:56,270,519...56,462,893
Ensembl chr13:56,270,781...56,462,834
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
ISO Cannabidiol results in increased phosphorylation of CREB1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased phosphorylation of CREB1 protein]; SB 203580 inhibits the reaction [Cannabidiol results in increased phosphorylation of CREB1 protein]
CTD PMID:28601556 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CREM mRNA] CTD PMID:27256343 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha affects methylation EXP Cannabidiol affects the methylation of CSF2RA gene CTD PMID:30521419 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264
JBrowse link
G Csnk1e casein kinase 1, epsilon affects methylation EXP Cannabidiol affects the methylation of CSNK1E gene CTD PMID:30521419 NCBI chr 7:120,651,976...120,675,559
Ensembl chr 7:120,651,881...120,672,359
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CSRNP1 mRNA] CTD PMID:27256343 NCBI chr 8:128,659,883...128,673,339
Ensembl chr 8:128,659,868...128,672,284
JBrowse link
G Ctsg cathepsin G increases expression ISO Cannabidiol results in increased expression of CTSG mRNA CTD PMID:21542829 NCBI chr15:35,107,333...35,113,678
Ensembl chr15:35,111,091...35,113,678
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases expression ISO Cannabidiol results in decreased expression of CX3CR1 mRNA CTD PMID:21542829 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 mRNA]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of CXCL10 protein] CTD PMID:32244040 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO Cannabidiol results in decreased expression of CXCL14 mRNA CTD PMID:21542829 NCBI chr17:9,109,731...9,117,754
Ensembl chr17:9,109,731...9,117,750
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCL9 mRNA] CTD PMID:27256343 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCR1 mRNA] CTD PMID:27256343 NCBI chr 9:81,466,430...81,469,299
Ensembl chr 9:81,466,332...81,469,274
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of CXCR4 mRNA
Cannabidiol results in increased expression of CXCR4 mRNA
CTD PMID:30742662 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO Cannabidiol results in decreased activity of CYP19A1 protein
Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of CYP19A1 mRNA]
CTD PMID:31953017 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Cannabidiol results in decreased activity of CYP1A1 protein CTD PMID:24667653 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Cannabidiol results in decreased activity of CYP1A2 protein CTD PMID:24667653 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity ISO Cannabidiol results in decreased activity of CYP2B10 CTD PMID:8043019 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity ISO Cannabidiol results in decreased activity of CYP2B6 protein CTD PMID:24667653 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity ISO Cannabidiol results in decreased activity of CYP2C9 protein CTD PMID:24667653 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO Cannabidiol results in decreased activity of CYP2C19 protein CTD PMID:24667653 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Cannabidiol results in decreased activity of CYP2D6 protein CTD PMID:24667653 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity
increases metabolic processing
multiple interactions
ISO Cannabidiol results in decreased activity of CYP3A4 protein
CYP3A11 protein results in increased metabolism of Cannabidiol
[CYP3A11 protein results in increased metabolism of Cannabidiol] which results in increased chemical synthesis of cannabidiol hydroxyquinone
CTD PMID:9778318 PMID:24667653 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases activity ISO Cannabidiol results in decreased activity of CYP3A5 protein CTD PMID:24667653 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyrib CYFIP related Rac1 interactor B decreases expression ISO Cannabidiol results in decreased expression of CYRIB mRNA CTD PMID:21542829 NCBI chr 7:104,514,566...104,641,875
Ensembl chr 7:104,516,391...104,556,419
JBrowse link
G Cytip cytohesin 1 interacting protein decreases expression ISO Cannabidiol results in decreased expression of CYTIP mRNA CTD PMID:21542829 NCBI chr 3:44,150,494...44,225,723
Ensembl chr 3:44,150,992...44,177,689
JBrowse link
G Dapk3 death-associated protein kinase 3 affects methylation EXP Cannabidiol affects the methylation of DAPK3 gene CTD PMID:30521419 NCBI chr 7:11,392,436...11,400,855
Ensembl chr 7:11,392,437...11,400,805
JBrowse link
G Dct dopachrome tautomerase increases expression
multiple interactions
ISO Cannabidiol results in increased expression of DCT mRNA; Cannabidiol results in increased expression of DCT protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of DCT mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of DCT mRNA]
CTD PMID:28601556 NCBI chr15:103,208,174...103,245,033
Ensembl chr15:103,208,258...103,244,494
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of DDIT3 mRNA
[Bilirubin co-treated with Rotenone] promotes the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]; Rotenone promotes the reaction [Cannabidiol results in increased expression of DDIT3 mRNA]
CTD PMID:21542829 PMID:32033040 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of DDIT4 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of DDIT4 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddr1 discoidin domain receptor tyrosine kinase 1 increases expression ISO Cannabidiol results in increased expression of DDR1 mRNA CTD PMID:27256343 NCBI chr20:3,553,430...3,574,959
Ensembl chr20:3,552,929...3,575,780
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of DGAT1 mRNA] CTD PMID:27256343 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 affects methylation EXP Cannabidiol affects the methylation of DLG4 gene CTD PMID:30521419 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions
increases expression
ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of DLL1 mRNA]
Cannabidiol results in increased expression of DLL1 mRNA
CTD PMID:30742662 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Dnmt3l DNA methyltransferase 3 like increases expression ISO Cannabidiol results in increased expression of DNMT3L mRNA CTD PMID:21542829 NCBI chr20:11,344,513...11,359,090
Ensembl chr20:11,344,514...11,359,090
JBrowse link
G Dok2 docking protein 2 decreases expression ISO Cannabidiol results in decreased expression of DOK2 mRNA CTD PMID:21542829 NCBI chr15:52,449,884...52,455,414
Ensembl chr15:52,451,161...52,456,409
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Cannabidiol results in increased expression of DUSP1 mRNA CTD PMID:21542829 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Cannabidiol co-treated with MOG protein modified form] results in increased expression of DUSP6 mRNA; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of DUSP6 mRNA] CTD PMID:27256343 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G E2f2 E2F transcription factor 2 increases expression ISO Cannabidiol results in increased expression of E2F2 mRNA CTD PMID:30742662 NCBI chr 5:154,516,611...154,540,228
Ensembl chr 5:154,522,119...154,540,265
JBrowse link
G E2f5 E2F transcription factor 5 decreases expression ISO Cannabidiol results in decreased expression of E2F5 mRNA CTD PMID:30742662 NCBI chr 2:88,350,764...88,366,913
Ensembl chr 2:88,351,361...88,366,115
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA; Pertussis Toxin inhibits the reaction [[Dronabinol co-treated with Cannabidiol] results in decreased expression of EGFR mRNA] CTD PMID:32049991 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO Cannabidiol results in increased expression of EIF4EBP1 mRNA CTD PMID:21542829 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A decreases expression ISO Cannabidiol results in decreased expression of EIF5A mRNA CTD PMID:21542829 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Eno2 enolase 2 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of ENO2 mRNA] CTD PMID:17672854 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression ISO Cannabidiol results in increased expression of EPHX1 mRNA CTD PMID:27256343 NCBI chr13:99,271,390...99,300,580
Ensembl chr13:99,271,366...99,300,579
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor increases expression ISO Cannabidiol results in increased expression of ETS2 mRNA CTD PMID:27256343 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Ezr ezrin affects methylation EXP Cannabidiol affects the methylation of EZR gene CTD PMID:30521419 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO Cannabidiol results in increased expression of F3 protein CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fabp1 fatty acid binding protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] CTD PMID:31110286 NCBI chr 4:99,063,181...99,066,957
Ensembl chr 4:99,063,181...99,066,954
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Cannabidiol results in increased expression of FAS mRNA CTD PMID:30742662 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Fdps farnesyl diphosphate synthase multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of FDPS mRNA] CTD PMID:27256343 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fgf12 fibroblast growth factor 12 affects methylation EXP Cannabidiol affects the methylation of FGF12 gene CTD PMID:30521419 NCBI chr11:75,606,360...76,171,078
Ensembl chr11:75,905,443...76,168,989
JBrowse link
G Fgf14 fibroblast growth factor 14 affects methylation EXP Cannabidiol affects the methylation of FGF14 gene CTD PMID:30521419 NCBI chr15:110,382,274...111,077,027
Ensembl chr15:110,385,217...110,612,681
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 affects methylation EXP Cannabidiol affects the methylation of FGFR2 gene CTD PMID:30521419 NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 affects methylation EXP Cannabidiol affects the methylation of FGFR4 gene CTD PMID:30521419 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of FOS mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of FOS mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of FOXO1 mRNA] CTD PMID:31953017 NCBI chr 2:141,451,234...141,527,016
Ensembl chr 2:141,451,234...141,527,016
JBrowse link
G Fzd9 frizzled class receptor 9 affects methylation EXP Cannabidiol affects the methylation of FZD9 gene CTD PMID:30521419 NCBI chr12:24,473,981...24,476,295
Ensembl chr12:24,473,981...24,476,295
JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions EXP Cannabidiol inhibits the reaction [Poly I-C results in decreased expression of GAD1 protein] CTD PMID:31202911 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Cannabidiol results in increased expression of GADD45A mRNA CTD PMID:21542829 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gas1 growth arrest-specific 1 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of GAS1 mRNA
Cannabidiol results in increased expression of GAS1 mRNA
CTD PMID:30742662 NCBI chr17:4,846,116...4,849,350
Ensembl chr17:4,846,789...4,847,940
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Cannabidiol results in increased expression of GCLM mRNA CTD PMID:21542829 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Cannabidiol results in increased expression of GDF15 mRNA CTD PMID:21542829 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdf6 growth differentiation factor 6 affects methylation EXP Cannabidiol affects the methylation of GDF6 gene CTD PMID:30521419 NCBI chr 5:23,056,345...23,072,666
Ensembl chr 5:23,056,347...23,074,599
JBrowse link
G Gfod1 glucose-fructose oxidoreductase domain containing 1 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA] CTD PMID:27256343 NCBI chr17:23,818,370...23,924,393
Ensembl chr17:23,823,632...23,923,792
JBrowse link
G Gli1 GLI family zinc finger 1 affects methylation EXP Cannabidiol affects the methylation of GLI1 gene CTD PMID:30521419 NCBI chr 7:70,620,794...70,633,171
Ensembl chr 7:70,620,766...70,630,338
JBrowse link
G Gnb2 G protein subunit beta 2 affects methylation EXP Cannabidiol affects the methylation of GNB2 gene CTD PMID:30521419 NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096
JBrowse link
G Gng7 G protein subunit gamma 7 affects methylation EXP Cannabidiol affects the methylation of GNG7 gene CTD PMID:30521419 NCBI chr 7:11,565,740...11,629,519
Ensembl chr 7:11,582,984...11,628,929
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Cannabidiol results in increased expression of GPNMB mRNA CTD PMID:27256343 NCBI chr 4:78,694,447...78,715,685
Ensembl chr 4:78,694,447...78,715,683
JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO Cannabidiol results in decreased expression of GPR183 mRNA CTD PMID:21542829 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221
JBrowse link
G Gpr83 G protein-coupled receptor 83 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of GPR83 mRNA] CTD PMID:27256343 NCBI chr 8:13,365,583...13,376,071
Ensembl chr 8:13,365,583...13,376,070
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 increases expression ISO Cannabidiol results in increased expression of GPT2 mRNA CTD PMID:21542829 NCBI chr19:22,599,003...22,633,529
Ensembl chr19:22,590,881...22,632,071
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity ISO Cannabidiol results in decreased activity of GSR protein CTD PMID:18929579 PMID:32752303 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Cannabidiol results in increased expression of GSTM1 mRNA CTD PMID:21542829 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Cannabidiol results in increased expression of H1F2 mRNA CTD PMID:21542829 NCBI chr17:43,638,938...43,640,445
Ensembl chr17:43,639,749...43,640,387
JBrowse link
G Hbp1 HMG-box transcription factor 1 increases expression ISO Cannabidiol results in increased expression of HBP1 mRNA CTD PMID:30742662 NCBI chr 6:51,231,479...51,257,699
Ensembl chr 6:51,231,480...51,257,625
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Cannabidiol results in increased expression of HERPUD1 mRNA CTD PMID:21542829 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes2 hes family bHLH transcription factor 2 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of HES2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of HES2 mRNA
CTD PMID:30742662 NCBI chr 5:169,338,097...169,339,142
Ensembl chr 5:169,338,097...169,339,142
JBrowse link
G Hgf hepatocyte growth factor affects methylation EXP Cannabidiol affects the methylation of HGF gene CTD PMID:30521419 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F increases expression ISO Cannabidiol results in increased expression of H2AC6 mRNA CTD PMID:21542829 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 increases expression ISO Cannabidiol results in increased expression of H3C6 mRNA CTD PMID:21542829 NCBI chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
Ensembl chr17:43,814,773...43,815,183
JBrowse link
G Hist2h2be histone cluster 2 H2B family member E increases expression ISO Cannabidiol results in increased expression of H2BC21 mRNA CTD PMID:21542829 NCBI chr 2:198,360,837...198,363,399
Ensembl chr 2:198,360,998...198,361,378
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
affects response to substance
ISO Cannabidiol results in increased expression of HMOX1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of HMOX1 mRNA; [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]; Rotenone promotes the reaction [Cannabidiol results in increased expression of HMOX1 mRNA]
Cannabidiol results in increased expression of HMOX1 mRNA; Cannabidiol results in increased expression of HMOX1 protein
HMOX1 protein affects the susceptibility to Cannabidiol
[bafilomycin A1 co-treated with tin protoporphyrin IX] promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased expression of HMOX1 protein]; iodopravadoline promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Cannabidiol results in increased expression of HMOX1 protein]; tin protoporphyrin IX promotes the reaction [Cannabidiol results in increased expression of HMOX1 protein]
CTD PMID:21542829 PMID:30349652 PMID:30742662 PMID:32033040 PMID:32708634 PMID:33076330 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A affects methylation EXP Cannabidiol affects the methylation of HNF1A gene CTD PMID:30521419 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hp haptoglobin increases expression ISO Cannabidiol results in increased expression of HP mRNA CTD PMID:21542829 NCBI chr19:42,096,255...42,100,805
Ensembl chr19:42,097,995...42,100,804
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Cannabidiol co-treated with Rotenone] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Cannabidiol co-treated with Rotenone] results in increased expression of HSPA5 mRNA] CTD PMID:32033040 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 increases expression ISO Cannabidiol results in increased expression of HTATIP2 mRNA CTD PMID:21542829 NCBI chr 1:105,094,272...105,109,459
Ensembl chr 1:105,094,411...105,109,461
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; AM 251 inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; capsazepine inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]; ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]; iodopravadoline inhibits the reaction [Cannabidiol results in increased expression of ICAM1 mRNA]
Cannabidiol results in increased expression of ICAM1 mRNA; Cannabidiol results in increased expression of ICAM1 protein
CTD PMID:22198381 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression
affects response to substance
ISO Cannabidiol results in decreased expression of ID1 mRNA; Cannabidiol results in decreased expression of ID1 protein
ID1 protein affects the susceptibility to Cannabidiol
CTD PMID:21542829 PMID:24910342 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 multiple interactions ISO AM 281 promotes the reaction [Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]]; Cannabidiol inhibits the reaction [[Plant Preparations results in increased activity of IDO1 protein] which results in increased abundance of Neopterin]; Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]; Cannabidiol inhibits the reaction [Plant Preparations results in increased expression of IDO1 mRNA]; iodopravadoline promotes the reaction [Cannabidiol inhibits the reaction [Plant Preparations results in increased activity of IDO1 protein]] CTD PMID:19167098 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IER3 mRNA] CTD PMID:27256343 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IFNB1 mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IFNB1 mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IFNB1 protein]
[Dronabinol co-treated with Cannabidiol] inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 protein]; Cannabidiol inhibits the reaction [Poly I-C results in increased expression of IFNB1 mRNA]
Cannabidiol results in increased expression of IFNB1 mRNA
CTD PMID:19910459 PMID:21542829 PMID:30742662 PMID:32244040 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol affects the reaction [Plant Preparations results in increased secretion of IFNG protein]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA]; Cannabidiol inhibits the reaction [Plant Preparations results in increased expression of IFNG mRNA] CTD PMID:19167098 PMID:31054246 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IFNGR1 mRNA] CTD PMID:27256343 NCBI chr 1:15,062,380...15,080,815
Ensembl chr 1:15,062,432...15,080,907
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of IGFBP1 mRNA] CTD PMID:31953017 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of IGFBP4 mRNA
Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IGFBP4 mRNA]
CTD PMID:21542829 PMID:27256343 NCBI chr10:86,950,555...86,962,563
Ensembl chr10:86,950,557...86,962,578
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA] CTD PMID:27256343 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
ISO
EXP
Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL1B protein]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of IL1B protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]
Cannabidiol results in decreased expression of IL1B mRNA
CTD PMID:19910459 PMID:21492165 PMID:21542829 PMID:27256343 PMID:27430346 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 increases expression ISO Cannabidiol results in increased expression of IL2 protein CTD PMID:11809870 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il3 interleukin 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL3 protein] CTD PMID:27256343 NCBI chr10:39,620,535...39,622,973
Ensembl chr10:39,620,563...39,622,973
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
ISO
EXP
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IL6 mRNA; [Rotenone co-treated with Bilirubin] inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]; Bilirubin inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]; Cannabidiol inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL6 protein]; Rotenone inhibits the reaction [Cannabidiol results in increased expression of IL6 mRNA]
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
CTD PMID:19910459 PMID:21350020 PMID:21492165 PMID:27430346 PMID:30742662 PMID:32033040 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO Cannabidiol results in decreased expression of IL6RA mRNA CTD PMID:30742662 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D decreases expression ISO Cannabidiol results in decreased expression of INPP5D mRNA CTD PMID:30742662 NCBI chr 9:94,745,220...94,850,778
Ensembl chr 9:94,745,217...94,850,771
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of IRAK1 protein] CTD PMID:19910459 NCBI chr  X:156,716,469...156,726,367
Ensembl chr  X:156,716,604...156,725,977
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of IRAK3 mRNA CTD PMID:30742662 NCBI chr 7:64,922,830...64,982,224
Ensembl chr 7:64,923,615...64,982,281
JBrowse link
G Irf3 interferon regulatory factor 3 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [Poly I-C affects the localization of IRF3 protein]; Cannabidiol inhibits the reaction [Poly I-C affects the localization of IRF3 protein] CTD PMID:32244040 NCBI chr 1:100,992,244...100,997,202
Ensembl chr 1:100,992,405...100,997,198
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions
increases expression
ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of IRF4 mRNA]
Cannabidiol results in increased expression of IRF4 mRNA
CTD PMID:27256343 NCBI chr17:34,886,746...34,905,191
Ensembl chr17:34,886,739...34,905,117
JBrowse link
G Itgb3 integrin subunit beta 3 affects methylation EXP Cannabidiol affects the methylation of ITGB3 gene CTD PMID:30521419 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Jak3 Janus kinase 3 affects methylation EXP Cannabidiol affects the methylation of JAK3 gene CTD PMID:30521419 NCBI chr16:20,107,471...20,120,678
Ensembl chr16:20,109,200...20,120,668
JBrowse link
G Jaml junction adhesion molecule like multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of JAML mRNA] CTD PMID:27256343 NCBI chr 8:49,378,644...49,408,894
Ensembl chr 8:49,378,644...49,410,088
JBrowse link
G Jdp2 Jun dimerization protein 2 increases expression ISO Cannabidiol results in increased expression of JDP2 mRNA CTD PMID:21542829 NCBI chr 6:109,464,910...109,505,591
Ensembl chr 6:109,466,060...109,505,161
JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Cannabidiol results in decreased expression of KCTD12 mRNA CTD PMID:21542829 NCBI chr15:87,384,632...87,390,627 JBrowse link
G Kras KRAS proto-oncogene, GTPase decreases expression EXP Cannabidiol results in decreased expression of KRAS mRNA CTD PMID:32553926 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Lamc1 laminin subunit gamma 1 affects methylation EXP Cannabidiol affects the methylation of LAMC1 gene CTD PMID:30521419 NCBI chr13:70,656,727...70,783,515
Ensembl chr13:70,658,707...70,783,515
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Cannabidiol results in increased expression of LCN2 mRNA CTD PMID:21542829 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Limk2 LIM domain kinase 2 affects methylation EXP Cannabidiol affects the methylation of LIMK2 gene CTD PMID:30521419 NCBI chr14:83,564,048...83,641,996
Ensembl chr14:83,573,928...83,641,892
JBrowse link
G Llgl1 LLGL scribble cell polarity complex component 1 affects methylation EXP Cannabidiol affects the methylation of LLGL1 gene CTD PMID:30521419 NCBI chr10:46,940,873...46,955,524
Ensembl chr10:46,940,965...46,954,674
JBrowse link
G LOC102553180 protocadherin alpha-1-like increases expression ISO Cannabidiol results in increased expression of PCDHA1 mRNA CTD PMID:21542829 NCBI chr18:29,824,891...29,839,850 JBrowse link
G Lpin1 lipin 1 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of LPIN1 mRNA
Cannabidiol results in increased expression of LPIN1 mRNA
CTD PMID:30742662 NCBI chr 6:41,796,214...41,905,149
Ensembl chr 6:41,799,749...41,870,046
JBrowse link
G Ly86 lymphocyte antigen 86 decreases expression ISO Cannabidiol results in decreased expression of LY86 mRNA CTD PMID:21542829 NCBI chr17:28,104,535...28,191,447
Ensembl chr17:28,104,589...28,191,436
JBrowse link
G Mafb MAF bZIP transcription factor B decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of MAFB mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MAFB mRNA
CTD PMID:30742662 NCBI chr 3:156,338,993...156,340,913
Ensembl chr 3:156,339,004...156,340,913
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects methylation EXP Cannabidiol affects the methylation of MAP2K1 gene CTD PMID:30521419 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 affects methylation EXP Cannabidiol affects the methylation of MAP2K6 gene CTD PMID:30521419 NCBI chr10:98,707,160...98,823,054
Ensembl chr10:98,706,960...98,823,287
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO Cannabidiol results in increased phosphorylation of MAPK1 protein CTD PMID:28601556 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression EXP Cannabidiol results in decreased expression of MAPK14 mRNA CTD PMID:32553926 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO Cannabidiol results in increased phosphorylation of MAPK3 protein CTD PMID:28601556 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapt microtubule-associated protein tau affects methylation EXP Cannabidiol affects the methylation of MAPT gene CTD PMID:30521419 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Cannabidiol results in decreased expression of MAT2A mRNA CTD PMID:21542829 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MDM2 mRNA
Cannabidiol results in increased expression of MDM2 mRNA
CTD PMID:30742662 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mecom MDS1 and EVI1 complex locus affects methylation EXP Cannabidiol affects the methylation of MECOM gene CTD PMID:30521419 NCBI chr 2:117,396,084...117,993,604
Ensembl chr 2:117,396,007...117,454,769
JBrowse link
G Mef2b myocyte enhancer factor 2B increases expression ISO Cannabidiol results in increased expression of MEF2B mRNA CTD PMID:21542829 NCBI chr16:21,001,204...21,017,651
Ensembl chr16:21,001,206...21,017,163
JBrowse link
G Mef2c myocyte enhancer factor 2C decreases expression ISO Cannabidiol results in decreased expression of MEF2C mRNA CTD PMID:21542829 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Mir145 microRNA 145 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR145A mRNA CTD PMID:30742662 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir146a microRNA 146a multiple interactions
decreases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR146 mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MIR146 mRNA]
Cannabidiol results in decreased expression of MIR146 mRNA
CTD PMID:30742662 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir155 microRNA 155 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MIR155 mRNA] CTD PMID:30742662 NCBI chr11:24,176,603...24,176,667
Ensembl chr11:24,176,603...24,176,667
JBrowse link
G Mir181b1 microRNA 181b-1 increases expression ISO Cannabidiol results in increased expression of MIR181B-1 mRNA CTD PMID:30742662 NCBI chr13:54,952,903...54,953,012
Ensembl chr13:54,952,903...54,953,012
JBrowse link
G Mir21 microRNA 21 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR21A mRNA CTD PMID:30742662 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir221 microRNA 221 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR221 mRNA CTD PMID:30742662 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir222 microRNA 222 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR222 mRNA CTD PMID:30742662 NCBI chr  X:3,683,919...3,684,021
Ensembl chr  X:3,683,919...3,684,021
JBrowse link
G Mir25 microRNA 25 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MIR25 mRNA CTD PMID:30742662 NCBI chr12:19,307,340...19,307,423
Ensembl chr12:19,307,340...19,307,423
JBrowse link
G Mir34a microRNA 34a multiple interactions
increases expression
ISO [Cannabidiol co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MIR34A mRNA
Cannabidiol results in increased expression of MIR34A mRNA
CTD PMID:30742662 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir449a microRNA 449a increases expression
multiple interactions
ISO Cannabidiol results in increased expression of MIR449A mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of MIR449A mRNA
CTD PMID:30742662 NCBI chr 2:44,897,601...44,897,691
Ensembl chr 2:44,897,601...44,897,691
JBrowse link
G Mitf melanocyte inducing transcription factor increases expression
multiple interactions
ISO Cannabidiol results in increased expression of MITF mRNA; Cannabidiol results in increased expression of MITF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of MITF mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of MITF mRNA]
CTD PMID:28601556 NCBI chr 4:130,172,484...130,425,496
Ensembl chr 4:130,172,727...130,425,532
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Cannabidiol results in decreased expression of MKI67 protein CTD PMID:24910342 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Cannabidiol results in increased expression of MMP23 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 5:173,078,811...173,082,834
Ensembl chr 5:173,078,590...173,081,839
JBrowse link
G Mog myelin oligodendrocyte glycoprotein multiple interactions ISO [Cannabidiol co-treated with MOG protein modified form] results in increased expression of DUSP6 mRNA; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of ATF3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CDK5R1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CREM mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CSRNP1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCL9 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of CXCR1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of DGAT1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of FDPS mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of GPR83 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IER3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IFNGR1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IGFBP4 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL12A mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL1B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of IL3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of JAML mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of NR4A3 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of SPHK1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF18 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF9 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF11 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF14 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TUBB2B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of VPS37B mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of XCL1 mRNA]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL1B protein]; Cannabidiol inhibits the reaction [MOG protein modified form results in increased secretion of IL3 protein]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of BTLA mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CD69 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of CMPK2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of DUSP6 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GBP11 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of GFOD1 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of IRF4 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of MX2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of PPIC mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of RSAD2 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TAGAP mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TNFSF8 mRNA]; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TRIM30A mRNA] CTD PMID:27256343 NCBI chr20:2,003,871...2,014,284
Ensembl chr20:2,004,052...2,014,286
JBrowse link
G Mr1 major histocompatibility complex, class I-related multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of MR1 mRNA
Cannabidiol results in increased expression of MR1 mRNA
CTD PMID:30742662 NCBI chr13:72,771,992...72,789,861
Ensembl chr13:72,771,984...72,789,841
JBrowse link
G Mt1 metallothionein 1 increases expression ISO Cannabidiol results in increased expression of MT1 mRNA CTD PMID:27256343 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Cannabidiol results in increased expression of MT2 mRNA CTD PMID:21542829 PMID:22178458 PMID:27256343 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mx2 MX dynamin like GTPase 2 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of MX2 mRNA] CTD PMID:27256343 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor affects methylation EXP Cannabidiol affects the methylation of MYC gene CTD PMID:30521419 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nckap1l NCK associated protein 1 like affects methylation EXP Cannabidiol affects the methylation of NCKAP1L gene CTD PMID:30521419 NCBI chr 7:145,068,239...145,113,507
Ensembl chr 7:145,068,286...145,113,507
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of NDRG1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of NDRG1 mRNA
CTD PMID:21542829 PMID:22178458 PMID:30742662 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Neurl1 neuralized E3 ubiquitin protein ligase 1 increases expression ISO Cannabidiol results in increased expression of NEURL1A mRNA CTD PMID:21542829 NCBI chr 1:266,953,006...267,038,879
Ensembl chr 1:266,952,561...267,038,883
JBrowse link
G Nfam1 NFAT activating protein with ITAM motif 1 decreases expression ISO Cannabidiol results in decreased expression of NFAM1 mRNA CTD PMID:21542829 NCBI chr 7:123,856,718...123,893,790
Ensembl chr 7:123,856,567...123,892,429
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 decreases expression
multiple interactions
ISO Cannabidiol results in decreased expression of NFATC2 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of NFATC2 mRNA
CTD PMID:30742662 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 increases expression ISO Cannabidiol results in increased expression of NFE2L1 mRNA CTD PMID:21542829 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of NFE2L2 protein
NFE2L2 protein affects the reaction [Cannabidiol results in increased expression of HMOX1 protein]
CTD PMID:32708634 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases expression ISO Cannabidiol results in increased expression of NFKB1 mRNA CTD PMID:21542829 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbib NFKB inhibitor beta increases expression ISO Cannabidiol results in increased expression of NFKBIB mRNA CTD PMID:21542829 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Cannabidiol results in increased expression of NOS2 mRNA
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS2 protein]
CTD PMID:27430346 PMID:30742662 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Cannabidiol results in increased expression of NQO1 mRNA CTD PMID:21542829 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of NR4A3 mRNA] CTD PMID:27256343 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 affects methylation EXP Cannabidiol affects the methylation of NTRK2 gene CTD PMID:30521419 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Cannabidiol results in increased expression of NUPR1 mRNA CTD PMID:21542829 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Oprd1 opioid receptor, delta 1 multiple interactions EXP Cannabidiol inhibits the reaction [naltrindole binds to and results in decreased activity of OPRD1 protein] CTD PMID:16489449 NCBI chr 5:150,288,126...150,323,063
Ensembl chr 5:150,288,126...150,323,063
JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions EXP Cannabidiol promotes the reaction [Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- binds to and results in increased activity of OPRM1 protein]] CTD PMID:16489449 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Pax8 paired box 8 affects methylation EXP Cannabidiol affects the methylation of PAX8 gene CTD PMID:30521419 NCBI chr 3:1,527,316...1,586,019
Ensembl chr 3:1,527,279...1,584,946
JBrowse link
G Pcdha1 protocadherin alpha 1 increases expression ISO Cannabidiol results in increased expression of PCDHA1 mRNA CTD PMID:21542829 NCBI chr18:29,951,094...30,215,896 JBrowse link
G Pcdha11 protocadherin alpha 11 increases expression ISO Cannabidiol results in increased expression of PCDHA11 mRNA CTD PMID:21542829 NCBI chr18:30,017,918...30,215,896
Ensembl chr18:29,987,206...30,215,897
JBrowse link
G Pdx1 pancreatic and duodenal homeobox 1 increases expression EXP Cannabidiol results in increased expression of PDX1 protein CTD PMID:32553926 NCBI chr12:9,496,044...9,501,211
Ensembl chr12:9,496,044...9,501,213
JBrowse link
G Penk proenkephalin multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of PENK mRNA] CTD PMID:17672854 NCBI chr 5:17,056,412...17,061,762
Ensembl chr 5:17,056,419...17,061,837
JBrowse link
G Pfn2 profilin 2 increases expression ISO Cannabidiol results in increased expression of PFN2 mRNA CTD PMID:21542829 NCBI chr 2:147,953,858...147,959,692
Ensembl chr 2:147,955,196...148,050,438
JBrowse link
G Pip5k1c phosphatidylinositol-4-phosphate 5-kinase type 1 gamma affects methylation EXP Cannabidiol affects the methylation of PIP5K1C gene CTD PMID:30521419 NCBI chr 7:11,267,207...11,294,291
Ensembl chr 7:11,267,218...11,294,249
JBrowse link
G Pitpnm2 phosphatidylinositol transfer protein, membrane-associated 2 increases expression ISO Cannabidiol results in increased expression of PITPNM2 mRNA CTD PMID:27256343 NCBI chr12:37,805,332...37,903,856
Ensembl chr12:37,805,332...37,903,855
JBrowse link
G Plin2 perilipin 2 increases expression ISO Cannabidiol results in increased expression of PLIN2 mRNA CTD PMID:21542829 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Plk2 polo-like kinase 2 increases expression ISO Cannabidiol results in increased expression of PLK2 mRNA CTD PMID:21542829 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Plpp3 phospholipid phosphatase 3 increases expression ISO Cannabidiol results in increased expression of PLPP3 mRNA CTD PMID:21542829 NCBI chr 5:124,690,214...124,765,499
Ensembl chr 5:124,690,214...124,765,498
JBrowse link
G Polr1g RNA polymerase I subunit G decreases expression ISO Cannabidiol results in decreased expression of CD3EAP mRNA CTD PMID:21542829 NCBI chr 1:80,267,725...80,271,001
Ensembl chr 1:80,267,725...80,271,001
JBrowse link
G Pomgnt2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) decreases expression ISO Cannabidiol results in decreased expression of POMGNT2 mRNA CTD PMID:21542829 NCBI chr 8:130,615,482...130,631,144
Ensembl chr 8:130,615,711...130,617,833
JBrowse link
G Pou5f1 POU class 5 homeobox 1 affects methylation EXP Cannabidiol affects the methylation of POU5F1 gene CTD PMID:30521419 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects methylation EXP Cannabidiol affects the methylation of PPARD gene CTD PMID:30521419 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions
affects binding
ISO
EXP
Cannabidiol results in increased expression of PPARG mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of PPARG mRNA
Cannabidiol binds to PPARG protein
Cannabidiol results in increased expression of and affects the localization of PPARG protein; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Cannabidiol affects the localization of PPARG protein]
CTD PMID:19285060 PMID:23220503 PMID:30742662 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppic peptidylprolyl isomerase C multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of PPIC mRNA] CTD PMID:27256343 NCBI chr18:48,372,039...48,384,645
Ensembl chr18:48,372,041...48,384,645
JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma affects methylation EXP Cannabidiol affects the methylation of PPP1CC gene CTD PMID:30521419 NCBI chr12:39,864,302...39,882,030
Ensembl chr12:39,864,295...39,882,030
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Cannabidiol results in increased expression of PPP1R15A mRNA CTD PMID:21542829 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha affects methylation EXP Cannabidiol affects the methylation of PRKACA gene CTD PMID:30521419 NCBI chr19:25,095,089...25,118,869
Ensembl chr19:25,095,089...25,118,860
JBrowse link
G Prl prolactin multiple interactions ISO Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Cyclic AMP] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased expression of PRL mRNA]; Cannabidiol inhibits the reaction [[Medroxyprogesterone Acetate co-treated with Estradiol co-treated with Colforsin] results in increased secretion of PRL protein] CTD PMID:31154070 PMID:31953017 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Ptch1 patched 1 affects methylation EXP Cannabidiol affects the methylation of PTCH1 gene CTD PMID:30521419 NCBI chr17:1,032,242...1,085,885
Ensembl chr17:1,029,048...1,093,873
JBrowse link
G Ptgir prostaglandin I2 receptor increases expression ISO Cannabidiol results in increased expression of PTGIR mRNA CTD PMID:21542829 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO
EXP
Cannabidiol results in increased expression of PTGS2 mRNA; Cannabidiol results in increased expression of PTGS2 protein
Cannabidiol inhibits the reaction [Hydrogen Peroxide results in increased expression of PTGS2 mRNA]
CTD PMID:23220503 PMID:27430346 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptpn14 protein tyrosine phosphatase, non-receptor type 14 increases expression ISO Cannabidiol results in increased expression of PTPN14 mRNA CTD PMID:21542829 NCBI chr13:108,689,916...108,841,593
Ensembl chr13:108,696,336...108,841,511
JBrowse link
G Ptprj protein tyrosine phosphatase, receptor type, J decreases expression ISO Cannabidiol results in decreased expression of PTPRJ mRNA CTD PMID:30742662 NCBI chr 3:79,233,519...79,390,956
Ensembl chr 3:79,233,525...79,390,956
JBrowse link
G Pvalb parvalbumin multiple interactions
increases expression
EXP [Poly I-C co-treated with Cannabidiol] results in increased expression of PVALB protein
Cannabidiol results in increased expression of PVALB protein
CTD PMID:31202911 PMID:31326506 NCBI chr 7:119,428,657...119,443,674
Ensembl chr 7:119,429,019...119,441,487
JBrowse link
G Rab3il1 RAB3A interacting protein-like 1 decreases expression ISO Cannabidiol results in decreased expression of RAB3IL1 mRNA CTD PMID:21542829 NCBI chr 1:226,077,182...226,084,830
Ensembl chr 1:226,077,120...226,084,830
JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 affects methylation EXP Cannabidiol affects the methylation of RASGRP1 gene CTD PMID:30521419 NCBI chr 3:108,984,029...109,044,420
Ensembl chr 3:108,984,029...109,044,420
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RELA mRNA; Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of RELA protein] CTD PMID:19910459 PMID:30742662 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO Cannabidiol results in increased expression of RELB mRNA CTD PMID:21542829 PMID:30742662 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rin2 Ras and Rab interactor 2 decreases expression ISO Cannabidiol results in decreased expression of RIN2 mRNA CTD PMID:21542829 NCBI chr 3:139,871,330...140,087,679
Ensembl chr 3:139,894,331...140,087,678
JBrowse link
G Rora RAR-related orphan receptor A multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RORA mRNA
Cannabidiol results in increased expression of RORA mRNA
CTD PMID:30742662 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Cannabidiol results in decreased phosphorylation of RPS6 protein CTD PMID:28392768 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions
increases expression
ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of RSAD2 mRNA; Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of RSAD2 mRNA]
Cannabidiol results in increased expression of RSAD2 mRNA
CTD PMID:27256343 PMID:30742662 NCBI chr 6:45,655,947...45,669,083
Ensembl chr 6:45,655,954...45,669,148
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 increases expression ISO Cannabidiol results in increased expression of S1PR1 mRNA CTD PMID:30742662 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Sars1 seryl-tRNA synthetase 1 increases expression ISO Cannabidiol results in increased expression of SARS mRNA CTD PMID:21542829 NCBI chr 2:211,219,743...211,235,475
Ensembl chr 2:211,219,750...211,235,467
JBrowse link
G Scin scinderin affects methylation EXP Cannabidiol affects the methylation of SCIN gene CTD PMID:30521419 NCBI chr 6:59,975,375...60,055,075
Ensembl chr 6:59,976,003...60,054,279
JBrowse link
G Serpine1 serpin family E member 1 decreases expression
increases response to substance
decreases secretion
multiple interactions
ISO Cannabidiol results in decreased expression of SERPINE1 mRNA
SERPINE1 protein results in increased susceptibility to Cannabidiol
Cannabidiol results in decreased secretion of SERPINE1 protein
CNR1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]; CNR2 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]; TRPV1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein]
CTD PMID:20668920 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sfxn4 sideroflexin 4 increases expression ISO Cannabidiol results in increased expression of SFXN4 mRNA CTD PMID:21542829 NCBI chr 1:282,213,610...282,236,851
Ensembl chr 1:282,213,675...282,235,974
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression ISO Cannabidiol results in increased expression of SLC1A4 mRNA CTD PMID:21542829 NCBI chr14:104,582,884...104,612,417
Ensembl chr14:104,581,190...104,612,597
JBrowse link
G Slc25a22 solute carrier family 25 member 22 decreases expression ISO Cannabidiol results in decreased expression of SLC25A22 mRNA CTD PMID:21542829 NCBI chr 1:214,410,388...214,418,236
Ensembl chr 1:214,410,417...214,414,897
JBrowse link
G Slc2a6 solute carrier family 2 member 6 increases expression ISO Cannabidiol results in increased expression of SLC2A6 mRNA CTD PMID:21542829 NCBI chr 3:5,567,729...5,575,144
Ensembl chr 3:5,568,321...5,575,136
JBrowse link
G Slc30a1 solute carrier family 30 member 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of SLC30A1 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of SLC30A1 mRNA
CTD PMID:21542829 PMID:22178458 PMID:27256343 PMID:30742662 NCBI chr13:110,677,810...110,681,683
Ensembl chr13:110,677,810...110,681,683
JBrowse link
G Slc39a10 solute carrier family 39 member 10 decreases expression ISO Cannabidiol results in decreased expression of SLC39A10 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Slc39a4 solute carrier family 39 member 4 increases expression ISO Cannabidiol results in increased expression of SLC39A4 mRNA CTD PMID:21542829 PMID:22178458 NCBI chr 7:117,675,718...117,682,586
Ensembl chr 7:117,675,720...117,680,004
JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Cannabidiol results in increased expression of SLC3A2 mRNA CTD PMID:21542829 PMID:27256343 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression ISO Cannabidiol results in increased expression of SLC40A1 mRNA CTD PMID:21542829 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc5a6 solute carrier family 5 member 6 decreases expression ISO Cannabidiol results in decreased expression of SLC5A6 mRNA CTD PMID:21542829 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Slc6a9 solute carrier family 6 member 9 increases expression ISO Cannabidiol results in increased expression of SLC6A9 mRNA CTD PMID:21542829 NCBI chr 5:136,669,674...136,703,702
Ensembl chr 5:136,669,674...136,703,697
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of SLC7A11 mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of SLC7A11 mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Sned1 sushi, nidogen and EGF-like domains 1 increases expression ISO Cannabidiol results in increased expression of SNED1 mRNA CTD PMID:21542829 NCBI chr 9:100,380,487...100,439,125
Ensembl chr 9:100,380,515...100,437,056
JBrowse link
G Soat2 sterol O-acyltransferase 2 increases expression ISO Cannabidiol results in increased expression of SOAT2 mRNA CTD PMID:21542829 NCBI chr 7:143,754,892...143,767,989
Ensembl chr 7:143,754,892...143,767,989
JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression ISO Cannabidiol results in increased expression of SOCS1 mRNA CTD PMID:30742662 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SOCS3 mRNA] CTD PMID:19910459 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of SOD1 mRNA] CTD PMID:17672854 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of SOD2 mRNA] CTD PMID:17672854 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sox4 SRY-box transcription factor 4 increases expression ISO Cannabidiol results in increased expression of SOX4 mRNA CTD PMID:21542829 NCBI chr17:37,615,022...37,619,728 JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of SPHK1 mRNA] CTD PMID:27256343 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G Spic Spi-C transcription factor increases expression ISO Cannabidiol results in increased expression of SPIC mRNA CTD PMID:21542829 NCBI chr 7:29,225,721...29,233,452
Ensembl chr 7:29,225,727...29,233,392
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Cannabidiol results in increased expression of SQSTM1 mRNA CTD PMID:21542829 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase affects methylation
increases expression
EXP
ISO
Cannabidiol affects the methylation of SRC gene
Cannabidiol results in increased expression of SRC mRNA
CTD PMID:30521419 PMID:30742662 NCBI chr 3:153,547,807...153,595,643
Ensembl chr 3:153,580,861...153,595,642
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Cannabidiol results in increased expression of SRXN1 mRNA CTD PMID:21542829 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Cannabidiol results in decreased expression of ST6GALNAC4 mRNA CTD PMID:21542829 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Cannabidiol results in increased expression of STAT1 mRNA CTD PMID:30742662 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO Cannabidiol inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and results in increased activity of STAT3 protein] CTD PMID:19910459 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stx11 syntaxin 11 increases expression ISO Cannabidiol results in increased expression of STX11 mRNA CTD PMID:21542829 NCBI chr 1:7,039,160...7,064,870
Ensembl chr 1:7,039,162...7,064,870
JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions EXP Cannabidiol inhibits the reaction [3-nitropropionic acid results in decreased expression of TAC1 mRNA] CTD PMID:17672854 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tagap T-cell activation RhoGTPase activating protein multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TAGAP mRNA] CTD PMID:27256343 NCBI chr 1:47,493,990...47,503,492
Ensembl chr 1:47,493,994...47,502,952
JBrowse link
G Tbx3 T-box transcription factor 3 affects methylation EXP Cannabidiol affects the methylation of TBX3 gene CTD PMID:30521419 NCBI chr12:42,479,518...42,494,588
Ensembl chr12:42,480,560...42,492,526
JBrowse link
G Tcf7l1 transcription factor 7 like 1 affects methylation EXP Cannabidiol affects the methylation of TCF7L1 gene CTD PMID:30521419 NCBI chr 4:100,492,796...100,660,401
Ensembl chr 4:100,491,798...100,660,140
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of CDH2 mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA] CTD PMID:32049991 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb3 transforming growth factor, beta 3 affects methylation EXP Cannabidiol affects the methylation of TGFB3 gene CTD PMID:30521419 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 affects methylation EXP Cannabidiol affects the methylation of TGFBR2 gene CTD PMID:30521419 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of TGIF2 mRNA CTD PMID:30742662 NCBI chr 3:152,906,961...152,924,380
Ensembl chr 3:152,909,189...152,924,377
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO Cannabidiol results in increased expression of TIMP1 mRNA; Cannabidiol results in increased expression of TIMP1 protein
ICAM1 mutant form inhibits the reaction [Cannabidiol results in increased expression of TIMP1 protein]
CTD PMID:22198381 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tle1 TLE family member 1, transcriptional corepressor decreases expression ISO Cannabidiol results in decreased expression of TLE1 mRNA CTD PMID:21542829 NCBI chr 5:88,546,607...88,630,277
Ensembl chr 5:88,546,568...88,629,491
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of TNF mRNA; Cannabidiol analog inhibits the reaction [Peptidoglycan results in increased expression of TNF protein]; Cannabidiol analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]
[Cannabidiol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; Cannabidiol analog inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:21492165 PMID:30742662 PMID:30796934 PMID:31054246 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO Cannabidiol results in increased expression of TNFAIP2 mRNA CTD PMID:21542829 NCBI chr 6:135,890,869...135,903,647
Ensembl chr 6:135,890,931...135,903,647
JBrowse link
G Tnfrsf18 TNF receptor superfamily member 18 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF18 mRNA] CTD PMID:27256343 NCBI chr 5:173,459,371...173,463,980
Ensembl chr 5:173,460,354...173,463,140
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFRSF9 mRNA] CTD PMID:27256343 NCBI chr 5:168,009,245...168,035,813
Ensembl chr 5:168,009,393...168,035,810
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF11 mRNA] CTD PMID:27256343 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tnfsf14 TNF superfamily member 14 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TNFSF14 mRNA] CTD PMID:27256343 NCBI chr 9:9,761,363...9,765,461
Ensembl chr 9:9,761,536...9,765,186
JBrowse link
G Tnfsf8 TNF superfamily member 8 multiple interactions ISO Cannabidiol promotes the reaction [MOG protein modified form results in increased expression of TNFSF8 mRNA] CTD PMID:27256343 NCBI chr 5:79,664,779...79,691,547
Ensembl chr 5:79,664,765...79,691,258
JBrowse link
G Top2a DNA topoisomerase II alpha multiple interactions
decreases activity
ISO Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]; Dithiothreitol inhibits the reaction [Cannabidiol metabolite inhibits the reaction [TOP2A protein results in increased hydrolysis of Adenosine Triphosphate]]
Cannabidiol metabolite results in decreased activity of TOP2A protein
CTD PMID:29272108 NCBI chr10:86,901,467...86,930,947
Ensembl chr10:86,901,007...86,932,154
JBrowse link
G Top2b DNA topoisomerase II beta multiple interactions
decreases activity
ISO Cannabidiol metabolite inhibits the reaction [TOP2B protein results in increased hydrolysis of Adenosine Triphosphate]
Cannabidiol metabolite results in decreased activity of TOP2B protein
CTD PMID:29272108 NCBI chr15:10,262,972...10,319,741
Ensembl chr15:10,262,651...10,320,233
JBrowse link
G Tp53 tumor protein p53 decreases expression EXP Cannabidiol results in decreased expression of TP53 mRNA CTD PMID:32553926 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Cannabidiol results in increased expression of TRP53INP1 mRNA CTD PMID:30742662 NCBI chr 5:24,402,895...24,419,651
Ensembl chr 5:24,410,863...24,416,888
JBrowse link
G Tpm3 tropomyosin 3 affects methylation EXP Cannabidiol affects the methylation of TPM3 gene CTD PMID:30521419 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO Cannabidiol results in increased expression of TRAF1 mRNA CTD PMID:21542829 NCBI chr 3:14,003,340...14,022,955
Ensembl chr 3:14,003,340...14,022,672
JBrowse link
G Traf3 Tnf receptor-associated factor 3 affects methylation EXP Cannabidiol affects the methylation of TRAF3 gene CTD PMID:30521419 NCBI chr 6:135,610,698...135,720,247
Ensembl chr 6:135,610,743...135,718,564
JBrowse link
G Trat1 T cell receptor associated transmembrane adaptor 1 increases expression ISO Cannabidiol results in increased expression of TRAT1 mRNA CTD PMID:27256343 NCBI chr11:54,619,169...54,661,284
Ensembl chr11:54,619,129...54,662,353
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Cannabidiol results in increased expression of TRIB3 mRNA CTD PMID:21542829 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions EXP Cannabidiol binds to and results in increased activity of TRPA1 protein CTD PMID:18550765 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; Cannabidiol inhibits the reaction [[Capsaicin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[resiniferatoxin binds to TRPV1 protein] which results in increased uptake of Calcium]; Cannabidiol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; Cannabidiol inhibits the reaction [Capsaicin binds to TRPV1 protein]; Cannabidiol inhibits the reaction [resiniferatoxin binds to TRPV1 protein]; capsazepine inhibits the reaction [[Cannabidiol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; capsazepine inhibits the reaction [Cannabidiol results in increased activity of TRPV1 protein]; TRPV1 protein promotes the reaction [Cannabidiol results in decreased secretion of SERPINE1 protein] CTD PMID:11606325 PMID:20668920 PMID:31054246 PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 increases activity
multiple interactions
ISO
EXP
Cannabidiol results in increased activity of TRPV2 protein
[Cannabidiol results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
Cannabidiol analog binds to and results in increased activity of TRPV2 protein; Cannabidiol binds to and results in increased activity of TRPV2 protein
CTD PMID:18550765 PMID:31096838 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030
JBrowse link
G Tubb2b tubulin, beta 2B class IIb multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of TUBB2B mRNA] CTD PMID:27256343 NCBI chr17:31,441,640...31,444,687
Ensembl chr17:31,441,630...31,482,759
JBrowse link
G Tyr tyrosinase multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased activity of TYR protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of TYR mRNA]; Cannabidiol results in increased expression of and results in increased activity of TYR protein; SB 203580 inhibits the reaction [Cannabidiol results in increased activity of TYR protein]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of TYR mRNA] CTD PMID:28601556 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Cannabidiol results in increased expression of TYRP1 mRNA]; SB 203580 inhibits the reaction [Cannabidiol results in increased expression of TYRP1 mRNA]
Cannabidiol results in increased expression of TYRP1 mRNA; Cannabidiol results in increased expression of TYRP1 protein
CTD PMID:28601556 NCBI chr 5:98,387,291...98,406,083
Ensembl chr 5:98,387,291...98,406,083
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO Cannabidiol results in decreased expression of USP2 mRNA CTD PMID:21542829 NCBI chr 8:48,403,985...48,432,525
Ensembl chr 8:48,406,260...48,430,885
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression
multiple interactions
ISO Cannabidiol results in increased expression of VEGFA mRNA
[lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in increased expression of VEGFA mRNA
CTD PMID:21542829 PMID:30742662 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vegfb vascular endothelial growth factor B affects methylation EXP Cannabidiol affects the methylation of VEGFB gene CTD PMID:30521419 NCBI chr 1:222,237,000...222,242,786
Ensembl chr 1:222,239,022...222,242,644
JBrowse link
G Vim vimentin multiple interactions ISO [Dronabinol co-treated with Cannabidiol] inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA]; Cannabidiol inhibits the reaction [TGFB1 protein results in increased expression of VIM mRNA] CTD PMID:32049991 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vps37b VPS37B subunit of ESCRT-I multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of VPS37B mRNA] CTD PMID:27256343 NCBI chr12:37,984,790...38,023,369
Ensembl chr12:37,984,790...38,023,368
JBrowse link
G Vwf von Willebrand factor increases expression ISO Cannabidiol results in increased expression of VWF mRNA CTD PMID:21542829 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
G Wasf2 WASP family member 2 affects methylation EXP Cannabidiol affects the methylation of WASF2 gene CTD PMID:30521419 NCBI chr 5:151,319,382...151,385,051
Ensembl chr 5:151,343,493...151,381,238
JBrowse link
G Wnt1 Wnt family member 1 multiple interactions ISO [lipopolysaccharide, E coli O55-B5 co-treated with Cannabidiol] results in decreased expression of WNT1 mRNA CTD PMID:30742662 NCBI chr 7:140,464,999...140,469,046
Ensembl chr 7:140,464,999...140,469,046
JBrowse link
G Wnt11 Wnt family member 11 affects methylation EXP Cannabidiol affects the methylation of WNT11 gene CTD PMID:30521419 NCBI chr 1:163,794,136...163,813,756
Ensembl chr 1:163,797,660...163,813,756
JBrowse link
G Wnt7b Wnt family member 7B affects methylation EXP Cannabidiol affects the methylation of WNT7B gene CTD PMID:30521419 NCBI chr 7:126,423,418...126,465,724
Ensembl chr 7:126,420,656...126,465,723
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO Cannabidiol results in increased expression of XBP1 mRNA CTD PMID:32033040 NCBI chr14:85,753,736...85,758,820
Ensembl chr14:85,753,760...85,758,145
JBrowse link
G Xcl1 X-C motif chemokine ligand 1 multiple interactions ISO Cannabidiol inhibits the reaction [MOG protein modified form results in increased expression of XCL1 mRNA] CTD PMID:27256343 NCBI chr13:83,199,402...83,202,845
Ensembl chr13:83,199,264...83,202,864
JBrowse link
cannabidiolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bhlhe41 basic helix-loop-helix family, member e41 increases expression ISO cannabidiolic acid results in increased expression of BHLHE41 mRNA CTD PMID:25242400 NCBI chr 4:180,230,742...180,235,138
Ensembl chr 4:180,232,382...180,234,804
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression ISO cannabidiolic acid results in decreased expression of FOS mRNA CTD PMID:27530354 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases expression ISO cannabidiolic acid results in increased expression of HTR1A mRNA CTD PMID:27530354 NCBI chr 2:36,246,628...36,247,896
Ensembl chr 2:36,246,628...36,247,896
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein decreases expression ISO cannabidiolic acid results in decreased expression of ID1 mRNA CTD PMID:25242400 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO cannabidiolic acid results in decreased expression of PTGS2 mRNA
cannabidiolic acid inhibits the reaction [GW 501516 results in increased expression of PTGS2 mRNA]; cannabidiolic acid promotes the reaction [GSK0660 results in decreased expression of PTGS2 mRNA]
CTD PMID:25242400 PMID:27530354 PMID:32238697 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity ISO cannabidiolic acid results in increased activity of TRPA1 protein CTD PMID:31096838 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpm8 transient receptor potential cation channel, subfamily M, member 8 decreases expression ISO cannabidiolic acid results in decreased expression of TRPM8 mRNA CTD PMID:27530354 NCBI chr 9:95,393,370...95,484,528
Ensembl chr 9:95,398,237...95,482,890
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 increases activity
multiple interactions
ISO cannabidiolic acid results in increased activity of TRPV1 protein
[cannabidiolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium
CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Trpv2 transient receptor potential cation channel, subfamily V, member 2 multiple interactions
increases expression
ISO [cannabidiolic acid results in increased activity of TRPV2 protein] which results in increased uptake of Calcium
cannabidiolic acid results in increased expression of TRPV2 mRNA
CTD PMID:27530354 PMID:31096838 NCBI chr10:48,903,540...48,925,036
Ensembl chr10:48,903,540...48,925,030
JBrowse link
cannabigerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL3 protein] CTD PMID:22971837 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO cannabigerol affects the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein] CTD PMID:22971837 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:22971837 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:22971837 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP cannabigerol inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:22971837 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [cannabigerol results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
cannabigerolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases activity
ISO [cannabigerolic acid results in increased activity of TRPV1 protein] which results in increased uptake of Calcium CTD PMID:31096838 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
Delta(9)-tetrahydrocannabinolic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression EXP delta(9)-tetrahydrocannabinolic acid results in increased expression of FOSB protein alternative form CTD PMID:18293355 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
HU-308 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of ARG1 mRNA] CTD PMID:29560022 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]] CTD PMID:27611972 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Becn1 beclin 1 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of BECN1 protein; HU 308 inhibits the reaction [Glucose results in decreased expression of BECN1 protein]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of BECN1 protein] CTD PMID:27611972 PMID:30459625 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Casp1 caspase 1 multiple interactions ISO 3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein]; [HU 308 co-treated with Dextran Sulfate] affects the cleavage of CASP1 protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein] CTD PMID:27611972 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Cd68 Cd68 molecule multiple interactions EXP HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CD68 protein] CTD PMID:29560022 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Chi3l3 chitinase 3-like 3 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CHI3L3 mRNA] CTD PMID:29560022 NCBI chr 2:208,899,871...208,936,858
Ensembl chr 2:208,900,103...208,936,860
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions EXP
ISO
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 mRNA]; HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of CNR2 protein]
[HU 308 co-treated with lipopolysaccharide, E. coli O26-B6] results in increased expression of CNR2 mRNA
CTD PMID:29560022 PMID:30232034 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Il10 interleukin 10 multiple interactions ISO
EXP
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 protein]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL10 mRNA]
CTD PMID:29560022 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B mRNA]
3-methyladenine affects the reaction [[HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein]; [HU 308 co-treated with Dextran Sulfate] affects the expression of IL1B protein; ATG5 protein affects the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]]; dorsomorphin inhibits the reaction [HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]]; HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL1B protein]; HU 308 inhibits the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]
CTD PMID:27611972 PMID:29560022 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of IL6 protein]
CTD PMID:29560022 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of MRC1 protein] CTD PMID:29560022 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of MTOR protein]; HU 308 inhibits the reaction [Glucose results in increased phosphorylation of MTOR protein]
CTD PMID:29560022 PMID:30459625 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of NFKBIA protein] CTD PMID:29560022 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of NLRP3 protein CTD PMID:27611972 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO
EXP
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of NOS2 protein] CTD PMID:29560022 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions EXP HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased phosphorylation of PIK3R1 protein] CTD PMID:29560022 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO HU 308 inhibits the reaction [Glucose results in increased phosphorylation of RPS6KB1 protein] CTD PMID:30459625 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [HU 308 co-treated with Dextran Sulfate] affects the expression of SQSTM1 protein; HU 308 inhibits the reaction [Glucose results in increased expression of SQSTM1 protein]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; HU 308 promotes the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in decreased expression of SQSTM1 protein] CTD PMID:27611972 PMID:30459625 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP
ISO
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 mRNA]
HU 308 promotes the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TGFB1 protein]
CTD PMID:29560022 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF mRNA]
HU 308 inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in increased expression of TNF protein]
CTD PMID:29560022 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
oleoyl ethanolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha increases response to substance
multiple interactions
ISO PPARA results in increased susceptibility to N-oleoylethanolamine
N-oleoylethanolamine binds to and results in increased activity of PPARA protein
CTD PMID:17906680 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO N-oleoylethanolamine results in decreased expression of PTGS2 protein CTD PMID:17906680 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
palmitoyl ethanolamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apob apolipoprotein B affects folding ISO palmidrol affects the folding of APOB protein CTD PMID:16115474 NCBI chr 6:33,176,826...33,216,381
Ensembl chr 6:33,176,778...33,224,997
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) multiple interactions ISO [palmidrol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 5:57,423,735...57,429,252
Ensembl chr 5:57,423,734...57,429,245
JBrowse link
G Aqp4 aquaporin 4 affects expression ISO palmidrol affects the expression of AQP4 mRNA CTD PMID:31054246 NCBI chr18:6,766,009...6,782,757
Ensembl chr18:6,765,945...6,782,996
JBrowse link
G Cldn3 claudin 3 multiple interactions
decreases expression
ISO [TNF protein co-treated with IFNG protein co-treated with palmidrol] results in decreased expression of CLDN3 mRNA
palmidrol results in decreased expression of CLDN3 mRNA
CTD PMID:31054246 NCBI chr12:21,831,341...21,832,813
Ensembl chr12:21,831,342...21,832,813
JBrowse link
G Cldn5 claudin 5 decreases expression ISO palmidrol results in decreased expression of CLDN5 mRNA CTD PMID:31054246 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions EXP [rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to palmidrol analog CTD PMID:17558434 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 affects binding
multiple interactions
ISO
EXP
palmidrol binds to CNR2 protein
[SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to palmidrol analog
CTD PMID:10617657 PMID:10688601 PMID:17558434 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions EXP palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] CTD PMID:26474837 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Ifng interferon gamma multiple interactions ISO [palmidrol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; [TNF protein co-treated with IFNG protein co-treated with palmidrol] results in decreased expression of CLDN3 mRNA; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] CTD PMID:26474837 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
affects localization
EXP [MK-886 binds to and results in decreased activity of PPARA protein] which results in decreased susceptibility to palmidrol analog; [palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]
palmidrol affects the localization of PPARA protein
CTD PMID:17558434 PMID:31787870 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [palmidrol co-treated with TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA; [TNF protein co-treated with IFNG protein co-treated with palmidrol] results in decreased expression of CLDN3 mRNA; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA]; palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of AQP3 mRNA] CTD PMID:31054246 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO palmidrol inhibits the reaction [[TNF protein co-treated with IFNG protein] results in decreased expression of TRPV1 mRNA] CTD PMID:31054246 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
WIN 55212-2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 decreases expression ISO Win 55212-2 results in decreased expression of ABCA2 mRNA CTD PMID:12237329 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects activity ISO Win 55212-2 affects the activity of ABCG2 protein CTD PMID:30083819 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acaca acetyl-CoA carboxylase alpha multiple interactions ISO Win 55212-2 inhibits the reaction [IL6 protein results in decreased phosphorylation of ACACA protein] CTD PMID:27324222 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO JTE 907 inhibits the reaction [Win 55212-2 analog results in decreased expression of ACTA2 protein]; Win 55212-2 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
Win 55212-2 inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Win 55212-2 inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
CTD PMID:31901889 PMID:31991773 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Adora2a adenosine A2a receptor decreases response to substance EXP ADORA2A protein results in decreased susceptibility to Win 55212-2 CTD PMID:26526685 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
Win 55212-2 results in increased phosphorylation of AKT1 protein
CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of AKT1 protein]; Win 55212-2 results in increased phosphorylation of and results in increased activity of AKT1 protein
CTD PMID:12734338 PMID:20619260 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression ISO Win 55212-2 results in decreased expression of APAF1 protein CTD PMID:30776504 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO Win 55212-2 inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA] CTD PMID:21350020 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Arg1 arginase 1 multiple interactions
affects expression
ISO AM6545 inhibits the reaction [Win 55212-2 affects the expression of ARG1 mRNA] CTD PMID:30184259 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO Win 55212-2 results in decreased expression of ARHGDIA mRNA CTD PMID:12237329 NCBI chr10:109,754,012...109,757,506
Ensembl chr10:109,754,004...109,757,550
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO GRK2 protein affects the reaction [Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]]; Win 55212-2 affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein] CTD PMID:31024316 NCBI chr 1:164,502,099...164,573,947
Ensembl chr 1:164,502,389...164,593,139
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [Win 55212-2 co-treated with CNR2 protein] affects the localization of ARRB2 protein; Win 55212-2 promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] CTD PMID:31024316 PMID:31901889 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Becn1 beclin 1 decreases expression ISO Win 55212-2 results in decreased expression of BECN1 protein CTD PMID:30776504 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Casp3 caspase 3 decreases cleavage ISO Win 55212-2 results in decreased cleavage of CASP3 protein CTD PMID:30776504 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 decreases cleavage ISO Win 55212-2 results in decreased cleavage of CASP7 protein CTD PMID:30776504 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 decreases cleavage ISO Win 55212-2 results in decreased cleavage of CASP8 protein CTD PMID:30776504 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO AM 281 inhibits the reaction [Win 55212-2 results in increased activity of CASP9 protein] CTD PMID:28495606 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Win 55212-2 results in decreased expression of CCT7 mRNA CTD PMID:12237329 NCBI chr 4:117,235,023...117,252,265
Ensembl chr 4:117,235,023...117,252,265
JBrowse link
G Cdk14 cyclin-dependent kinase 14 increases expression ISO Win 55212-2 results in increased expression of CDK14 mRNA CTD PMID:12237329 NCBI chr 4:25,825,567...26,419,443
Ensembl chr 4:25,825,567...26,419,127
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression ISO Win 55212-2 results in increased expression of CITED2 mRNA; Win 55212-2 results in increased expression of CITED2 protein CTD PMID:12237329 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cldn1 claudin 1 multiple interactions ISO [Win 55212-2 co-treated with Dextran Sulfate] results in decreased expression of CLDN1 protein CTD PMID:27920472 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
decreases expression
affects localization
increases activity
affects binding
ISO
EXP
CNR1 affects the reaction [Win 55212-2 results in increased activity of MAPK1 protein]; CNR1 affects the reaction [Win 55212-2 results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [Win 55212-2 results in increased activity of CNR1]; Rimonabant inhibits the reaction [Win 55212-2 results in increased activity of CNR1]; Win 55212-2 affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; Win 55212-2 binds to and results in increased activity of CNR1 protein; Win 55212-2 inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR1 protein]; Win 55212-2 promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]
CNR1 protein mutant form affects the susceptibility to Win 55212-2
Win 55212-2 results in decreased expression of CNR1 mRNA; Win 55212-2 results in decreased expression of CNR1 protein
Win 55212-2 affects the localization of CNR1 protein
[Rimonabant binds to and results in decreased activity of CNR1 protein] which results in decreased susceptibility to Win 55212-2; [Win 55212-2 binds to and results in increased activity of CNR1 protein] affects the reaction [Potassium Chloride results in increased transport of Calcium]; AM 251 inhibits the reaction [Win 55212-2 results in decreased expression of CNR1 mRNA]; AM 251 inhibits the reaction [Win 55212-2 results in decreased expression of CNR1 protein]; CNR1 protein affects the reaction [Win 55212-2 inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Rimonabant inhibits the reaction [[Win 55212-2 binds to and results in increased activity of CNR1 protein] inhibits the reaction [Potassium Chloride results in increased transport of Calcium]]; Win 55212-2 binds to and results in increased activity of CNR1 protein
[Win 55212-2 binds to and results in increased activity of CNR1 protein] which results in increased expression of FOS protein; CNRIP1 protein inhibits the reaction [Win 55212-2 affects the localization of CNR1 protein]; Win 55212-2 binds to and results in increased activity of CNR1 protein
Win 55212-2 binds to CNR1 protein
CTD PMID:8526880 PMID:10871313 PMID:12421626 PMID:12560108 PMID:16438957 PMID:17572696 PMID:21281698 PMID:22044209 PMID:22971837 PMID:27513693 PMID:29113897 PMID:30165669 PMID:30629988 PMID:31024316 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 affects response to substance
multiple interactions
affects binding
ISO
EXP
CNR2 gene SNP affects the susceptibility to Win 55212-2
[Win 55212-2 co-treated with CNR2 protein] affects the localization of ARRB2 protein; GRK2 protein affects the reaction [Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]]; ridaifen-B inhibits the reaction [Win 55212-2 binds to and results in increased activity of CNR2 protein]; Win 55212-2 binds to and results in increased activity of CNR2 protein; Win 55212-2 inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to CNR2 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]
Win 55212-2 binds to CNR2 protein
[SR 144528 binds to and results in decreased activity of CNR2 protein] which results in decreased susceptibility to Win 55212-2; CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of AKT1 protein]; CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Win 55212-2 binds to and results in increased activity of CNR2 protein
CTD PMID:10688601 PMID:12734338 PMID:17572696 PMID:20124950 PMID:21281698 PMID:21871882 PMID:22044209 PMID:22971837 PMID:29906493 PMID:31024316 PMID:31901889 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 multiple interactions ISO CNRIP1 protein inhibits the reaction [Win 55212-2 affects the localization of CNR1 protein] CTD PMID:27513693 NCBI chr14:100,217,547...100,247,235
Ensembl chr14:100,217,289...100,247,235
JBrowse link
G Ctsd cathepsin D increases expression ISO Win 55212-2 results in increased expression of CTSD protein CTD PMID:30776504 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Win 55212-2 results in increased expression of DDIT3 mRNA]; methyl-beta-cyclodextrin inhibits the reaction [Win 55212-2 results in increased expression of DDIT3 mRNA] CTD PMID:30502353 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Efs embryonal Fyn-associated substrate decreases expression ISO Win 55212-2 results in decreased expression of EFS mRNA CTD PMID:12237329 NCBI chr15:33,579,952...33,590,217
Ensembl chr15:33,578,381...33,589,522
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
increases phosphorylation
ISO RTKI cpd inhibits the reaction [Win 55212-2 results in increased phosphorylation of EGFR protein] CTD PMID:20619260 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression ISO Win 55212-2 results in decreased expression of EIF4B mRNA CTD PMID:12237329 NCBI chr 7:143,679,656...143,701,452
Ensembl chr 7:143,679,617...143,701,452
JBrowse link
G Eno2 enolase 2 decreases expression
multiple interactions
ISO Win 55212-2 results in decreased expression of ENO2 protein
Win 55212-2 inhibits the reaction [IL6 protein results in increased expression of ENO2 protein]
CTD PMID:27324222 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO Win 55212-2 inhibits the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; Win 55212-2 inhibits the reaction [IL1B protein results in increased expression of F3 mRNA] CTD PMID:27556861 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
affects expression
ISO
EXP
[Acetaminophen co-treated with Win 55212-2] results in decreased expression of FAAH mRNA
Win 55212-2 affects the expression of FAAH mRNA
[Win 55212-2 co-treated with Rimonabant] affects the expression of FAAH mRNA
CTD PMID:30165669 PMID:32833042 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Faahl fatty-acid amide hydrolase-like multiple interactions ISO [Acetaminophen co-treated with Win 55212-2] results in decreased expression of FAAH mRNA CTD PMID:30165669 NCBI chr 5:134,330,204...134,349,400
Ensembl chr 5:134,331,929...134,348,995
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Win 55212-2 binds to and results in increased activity of CNR1 protein] which results in increased expression of FOS protein CTD PMID:12560108 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Gck glucokinase increases expression ISO Win 55212-2 results in increased expression of GCK mRNA; Win 55212-2 results in increased expression of GCK protein CTD PMID:12237329 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gphn gephyrin multiple interactions EXP Win 55212-2 promotes the reaction [Cocaine results in increased phosphorylation of GPHN protein] CTD PMID:32312805 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Gpr55 G protein-coupled receptor 55 affects response to substance ISO GPR55 protein affects the susceptibility to Win 55212-2 CTD PMID:31877572 NCBI chr 9:92,961,431...93,011,157
Ensembl chr 9:92,962,738...92,963,697
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Win 55212-2 results in decreased expression of GRIA1 protein CTD PMID:32312805 NCBI chr10:42,441,723...42,760,200
Ensembl chr10:42,614,713...42,760,200
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Win 55212-2 results in decreased expression of GRIA2 protein CTD PMID:32312805 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO Win 55212-2 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein] CTD PMID:28092019 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO GRK2 protein affects the reaction [Win 55212-2 promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Hdac6 histone deacetylase 6 multiple interactions EXP Win 55212-2 promotes the reaction [Cocaine results in decreased expression of HDAC6 protein] CTD PMID:32312805 NCBI chr  X:15,295,372...15,316,673
Ensembl chr  X:15,295,473...15,316,671
JBrowse link
G Hspb3 heat shock protein family B (small) member 3 increases expression ISO Win 55212-2 results in increased expression of HSPB3 mRNA CTD PMID:12237329 NCBI chr 2:45,517,788...45,518,502
Ensembl chr 2:45,517,789...45,518,502
JBrowse link
G Htatsf1 HIV-1 Tat specific factor 1 multiple interactions EXP [Win 55212-2 co-treated with Cocaine] results in decreased phosphorylation of HTATSF1 protein CTD PMID:32312805 NCBI chr  X:159,514,053...159,528,281
Ensembl chr  X:159,513,800...159,528,281
JBrowse link
G Il10 interleukin 10 multiple interactions EXP
ISO
iodopravadoline inhibits the reaction [Win 55212-2 promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]]; Win 55212-2 promotes the reaction [Carbon Monoxide results in increased expression of IL10 protein]
Win 55212-2 promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL10 protein]
CTD PMID:31732924 PMID:32385136 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Win 55212-2 inhibits the reaction [IL1B protein results in increased abundance of N-palmitoylsphingosine]; Win 55212-2 inhibits the reaction [IL1B protein results in increased expression of and results in increased activity of F3 protein]; Win 55212-2 inhibits the reaction [IL1B protein results in increased expression of F3 mRNA]
iodopravadoline inhibits the reaction [Win 55212-2 inhibits the reaction [Carbon Monoxide results in increased expression of IL1B protein]]; Win 55212-2 inhibits the reaction [Carbon Monoxide results in increased expression of IL1B protein]
CTD PMID:27556861 PMID:31732924 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions EXP iodopravadoline inhibits the reaction [Win 55212-2 promotes the reaction [Carbon Monoxide results in increased expression of IL1RL1 protein]]; Win 55212-2 promotes the reaction [Carbon Monoxide results in increased expression of IL1RL1 protein] CTD PMID:31732924 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il33 interleukin 33 multiple interactions EXP AM 251 inhibits the reaction [Win 55212-2 promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein]]; Win 55212-2 promotes the reaction [Carbon Monoxide results in increased expression of IL33 protein] CTD PMID:31732924 NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
JBrowse link
G Il4 interleukin 4 multiple interactions EXP [Carbon Monoxide co-treated with Win 55212-2] results in increased expression of IL4 protein; iodopravadoline inhibits the reaction [[Carbon Monoxide co-treated with Win 55212-2] results in increased expression of IL4 protein] CTD PMID:31732924 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Win 55212-2 inhibits the reaction [APP alternative form results in increased expression of IL6 mRNA]; Win 55212-2 inhibits the reaction [Dextran Sulfate results in increased expression of IL6 protein]
Win 55212-2 inhibits the reaction [IL6 protein results in decreased phosphorylation of ACACA protein]; Win 55212-2 inhibits the reaction [IL6 protein results in decreased phosphorylation of PRKAA1 protein]; Win 55212-2 inhibits the reaction [IL6 protein results in increased expression of ENO2 protein]; Win 55212-2 inhibits the reaction [IL6 protein results in increased expression of TUBB3 protein]
CTD PMID:21350020 PMID:27324222 PMID:27920472 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Kdr kinase insert domain receptor multiple interactions ISO fumonisin B1 inhibits the reaction [Win 55212-2 results in decreased phosphorylation of and results in decreased activity of KDR protein]; Win 55212-2 results in decreased phosphorylation of and results in decreased activity of KDR protein CTD PMID:15313899 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Map2 microtubule-associated protein 2 decreases expression ISO Win 55212-2 results in decreased expression of MAP2 mRNA CTD PMID:12237329 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
increases phosphorylation
ISO
EXP
CNR1 affects the reaction [Win 55212-2 results in increased activity of MAPK1 protein]
CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Rimonabant inhibits the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Win 55212-2 promotes the reaction [Cocaine results in increased expression of MAPK1 protein]; Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK1 protein
Win 55212-2 results in increased phosphorylation of MAPK1 protein
CTD PMID:8526880 PMID:12657697 PMID:12734338 PMID:20619260 PMID:32312805 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases activity
multiple interactions
increases phosphorylation
ISO
EXP
Win 55212-2 results in increased activity of MAPK3 protein
CNR2 protein affects the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Win 55212-2 promotes the reaction [Cocaine results in increased expression of MAPK3 protein]; Win 55212-2 results in increased phosphorylation of and results in increased activity of MAPK3 protein
Win 55212-2 results in increased phosphorylation of MAPK3 protein
CNR1 affects the reaction [Win 55212-2 results in increased activity of MAPK3 protein]
CTD PMID:8526880 PMID:12657697 PMID:12734338 PMID:20619260 PMID:32312805 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation ISO Win 55212-2 results in increased phosphorylation of MAPK8 protein CTD PMID:20619260 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation ISO Win 55212-2 results in increased phosphorylation of MAPK9 protein CTD PMID:20619260 NCBI chr10:35,333,859...35,374,364
Ensembl chr10:35,333,859...35,374,355
JBrowse link
G Mapt microtubule-associated protein tau increases expression ISO Win 55212-2 results in increased expression of MAPT mRNA CTD PMID:12237329 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Win 55212-2 results in decreased expression of MAT2A mRNA CTD PMID:12237329 NCBI chr 4:100,297,478...100,303,047
Ensembl chr 4:100,296,075...100,303,080
JBrowse link
G Mgll monoglyceride lipase affects response to substance ISO MGLL protein affects the susceptibility to Win 55212-2 CTD PMID:21911610 NCBI chr 4:120,671,436...120,773,458
Ensembl chr 4:120,671,489...120,771,088
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity
decreases expression
multiple interactions
ISO Win 55212-2 results in decreased activity of MMP2 protein
Win 55212-2 analog results in decreased expression of MMP2 protein
JTE 907 inhibits the reaction [Win 55212-2 analog results in decreased expression of MMP2 protein]
CTD PMID:30776504 PMID:31991773 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity ISO Win 55212-2 results in decreased activity of MMP9 protein CTD PMID:30776504 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Morf4l1 mortality factor 4 like 1 decreases expression ISO Win 55212-2 results in decreased expression of MORF4L1 mRNA CTD PMID:12237329 NCBI chr 8:97,473,454...97,494,974
Ensembl chr 8:97,474,092...97,494,834
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Win 55212-2 inhibits the reaction [Dextran Sulfate results in increased activity of MPO protein] CTD PMID:27920472 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions EXP [Win 55212-2 co-treated with Carbon Monoxide] results in increased expression of MRC1 protein; iodopravadoline inhibits the reaction [[Win 55212-2 co-treated with Carbon Monoxide] results in increased expression of MRC1 protein] CTD PMID:31732924 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO Win 55212-2 results in increased expression of MYC mRNA CTD PMID:12237329 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Napepld N-acyl phosphatidylethanolamine phospholipase D multiple interactions EXP [Win 55212-2 co-treated with Rimonabant] affects the expression of NAPEPLD mRNA CTD PMID:32833042 NCBI chr 4:9,965,323...10,004,650
Ensembl chr 4:9,966,891...10,002,247
JBrowse link
G Ndrg4 NDRG family member 4 decreases expression ISO Win 55212-2 results in decreased expression of NDRG4 mRNA CTD PMID:12237329 NCBI chr19:9,766,439...9,802,396
Ensembl chr19:9,766,439...9,801,942
JBrowse link
G Nedd4l NEDD4 like E3 ubiquitin protein ligase decreases expression ISO Win 55212-2 results in decreased expression of NEDD4L mRNA CTD PMID:12237329 NCBI chr18:60,392,376...60,719,720
Ensembl chr18:60,392,376...60,719,720
JBrowse link
G Nfatc4 nuclear factor of activated T-cells 4 increases localization EXP Win 55212-2 results in increased localization of NFATC4 protein CTD PMID:16849427 NCBI chr15:34,493,163...34,502,238
Ensembl chr15:34,493,138...34,504,326
JBrowse link
G Npas2 neuronal PAS domain protein 2 multiple interactions EXP Win 55212-2 promotes the reaction [Cocaine results in increased splicing of NPAS2 mRNA] CTD PMID:32312805 NCBI chr 9:45,901,262...46,081,880
Ensembl chr 9:45,901,741...46,081,880
JBrowse link
G Ntn1 netrin 1 increases expression ISO Win 55212-2 results in increased expression of NTN1 mRNA CTD PMID:12237329 NCBI chr10:54,761,925...54,982,072
Ensembl chr10:54,761,871...54,967,585
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Acetaminophen co-treated with Win 55212-2] results in decreased expression of NTRK2 mRNA CTD PMID:30165669 NCBI chr17:5,934,651...6,245,778
Ensembl chr17:5,933,729...6,244,676
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 decreases expression ISO Win 55212-2 results in decreased expression of PACSIN1 mRNA CTD PMID:12237329 NCBI chr20:7,241,248...7,286,702
Ensembl chr20:7,279,820...7,286,586
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases expression ISO Win 55212-2 results in decreased expression of PARP1 protein CTD PMID:30776504 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Perp p53 apoptosis effector related to PMP22 increases expression ISO Win 55212-2 results in increased expression of PERP mRNA CTD PMID:12237329 NCBI chr 1:14,224,392...14,236,838
Ensembl chr 1:14,224,393...14,236,846
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO Win 55212-2 binds to and results in increased activity of PPARA protein CTD PMID:17906680 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha decreases expression ISO Win 55212-2 results in decreased expression of PPP2R1A mRNA CTD PMID:12237329 NCBI chr 1:60,717,386...60,736,629
Ensembl chr 1:60,717,386...60,736,609
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 multiple interactions ISO Win 55212-2 inhibits the reaction [IL6 protein results in decreased phosphorylation of PRKAA1 protein] CTD PMID:27324222 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
affects expression
EXP [Win 55212-2 co-treated with Rimonabant] affects the expression of PTEN mRNA
Win 55212-2 affects the expression of PTEN mRNA
CTD PMID:32833042 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression ISO Win 55212-2 results in decreased expression of PTGDS mRNA CTD PMID:12237329 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N decreases expression ISO Win 55212-2 results in decreased expression of PTPRN mRNA CTD PMID:12237329 NCBI chr 9:82,446,626...82,462,314
Ensembl chr 9:82,446,633...82,461,903
JBrowse link
G Rfc1 replication factor C subunit 1 increases expression ISO Win 55212-2 results in increased expression of RFC1 mRNA CTD PMID:12237329 NCBI chr14:44,627,528...44,702,205
Ensembl chr14:44,580,216...44,702,203
JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 decreases expression ISO Win 55212-2 results in decreased expression of RIPK1 protein CTD PMID:30776504 NCBI chr17:31,537,580...31,569,904
Ensembl chr17:31,537,591...31,569,904
JBrowse link
G Rtn3 reticulon 3 decreases expression ISO Win 55212-2 results in decreased expression of RTN3 mRNA CTD PMID:12237329 NCBI chr 1:222,677,359...222,734,307
Ensembl chr 1:222,677,365...222,734,241
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 increases expression ISO Win 55212-2 results in increased expression of S1PR3 mRNA CTD PMID:12237329 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G Serpine2 serpin family E member 2 decreases expression ISO Win 55212-2 results in decreased expression of SERPINE2 mRNA CTD PMID:12237329 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Slc12a5 solute carrier family 12 member 5 affects expression EXP Win 55212-2 affects the expression of SLC12A5 mRNA; Win 55212-2 affects the expression of SLC12A5 protein CTD PMID:31653479 NCBI chr 3:161,433,303...161,465,078
Ensembl chr 3:161,425,988...161,462,879
JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases expression EXP Win 55212-2 results in increased expression of SLC1A1 protein CTD PMID:17631920 NCBI chr 1:246,955,017...247,035,159
Ensembl chr 1:246,954,980...247,037,056
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Win 55212-2 results in increased expression of SLC1A2 protein CTD PMID:17631920 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc6a1 solute carrier family 6 member 1 multiple interactions ISO Win 55212-2 inhibits the reaction [Isoproterenol results in increased expression of SLC6A1 protein] CTD PMID:30170018 NCBI chr 4:146,258,842...146,292,176
Ensembl chr 4:146,276,862...146,292,213
JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects expression
multiple interactions
EXP Win 55212-2 affects the expression of SLC6A3 mRNA; Win 55212-2 affects the expression of SLC6A3 protein
AM 251 affects the reaction [Win 55212-2 affects the expression of SLC6A3 mRNA]
CTD PMID:29113897 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Smn1 survival of motor neuron 1, telomeric decreases expression ISO Win 55212-2 results in decreased expression of SMN1 mRNA CTD PMID:12237329 NCBI chr 2:30,360,101...30,371,147
Ensembl chr 2:30,360,100...30,371,147
JBrowse link
G Syp synaptophysin multiple interactions ISO [Acetaminophen co-treated with Win 55212-2] results in decreased expression of SYP mRNA CTD PMID:30165669 NCBI chr  X:15,694,699...15,709,244
Ensembl chr  X:15,695,566...15,707,436
JBrowse link
G Tagln3 transgelin 3 decreases expression ISO Win 55212-2 results in decreased expression of TAGLN3 mRNA CTD PMID:12237329 NCBI chr11:60,072,983...60,086,552
Ensembl chr11:60,072,727...60,086,553
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Win 55212-2 inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
Win 55212-2 inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
CTD PMID:31901889 PMID:31991773 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase multiple interactions
affects expression
EXP
ISO
AM 251 affects the reaction [Win 55212-2 affects the expression of TH mRNA]
Win 55212-2 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]
Win 55212-2 affects the expression of TH mRNA; Win 55212-2 affects the expression of TH protein
CTD PMID:28092019 PMID:29113897 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
iodopravadoline inhibits the reaction [Win 55212-2 inhibits the reaction [Carbon Monoxide results in increased expression of TNF protein]]; Win 55212-2 inhibits the reaction [Carbon Monoxide results in increased expression of TNF protein]; Win 55212-2 inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
Win 55212-2 inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Win 55212-2 inhibits the reaction [Dextran Sulfate results in increased expression of TNF protein]
CTD PMID:12509806 PMID:27920472 PMID:31732924 PMID:31901889 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression ISO Win 55212-2 results in increased expression of TP53 protein CTD PMID:30776504 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Traf5 TNF receptor-associated factor 5 increases expression ISO Win 55212-2 results in increased expression of TRAF5 mRNA CTD PMID:12237329 NCBI chr13:110,758,556...110,801,871
Ensembl chr13:110,758,761...110,784,209
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Win 55212-2 results in increased expression of TRIB3 protein CTD PMID:16818650 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim8 tripartite motif-containing 8 increases expression ISO Win 55212-2 results in increased expression of TRIM8 mRNA CTD PMID:12237329 NCBI chr 1:266,255,797...266,270,694
Ensembl chr 1:266,255,797...266,270,694
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 multiple interactions
increases response to substance
EXP
ISO
TRPA1 promotes the reaction [Win 55212-2 results in increased abundance of Calcium]; Win 55212-2 binds to and results in increased activity of TRPA1 protein
TRPA1 results in increased susceptibility to Win 55212-2
CTD PMID:18234885 PMID:18550765 NCBI chr 5:3,783,247...3,836,485
Ensembl chr 5:3,783,247...3,836,485
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
decreases phosphorylation
EXP Win 55212-2 binds to and results in increased activity of TRPV1 protein
Win 55212-2 results in decreased phosphorylation of TRPV1 protein
CTD PMID:16849427 PMID:18550765 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Tubb3 tubulin, beta 3 class III decreases expression
multiple interactions
ISO Win 55212-2 results in decreased expression of TUBB3 protein
Win 55212-2 inhibits the reaction [IL6 protein results in increased expression of TUBB3 protein]
CTD PMID:27324222 NCBI chr19:56,220,759...56,229,813
Ensembl chr19:56,220,755...56,229,813
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Win 55212-2 results in decreased expression of and results in decreased secretion of VEGFA protein
fumonisin B1 inhibits the reaction [Win 55212-2 results in decreased expression of and results in decreased secretion of VEGFA protein]; rimonabant inhibits the reaction [Win 55212-2 results in decreased expression of and results in decreased secretion of VEGFA protein]; SR 144528 inhibits the reaction [Win 55212-2 results in decreased expression of and results in decreased secretion of VEGFA protein]; Win 55212-2 results in decreased expression of and results in decreased secretion of VEGFA protein
CTD PMID:15313899 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vps26c VPS26 endosomal protein sorting factor C increases expression ISO Win 55212-2 results in increased expression of VPS26C mRNA CTD PMID:12237329 NCBI chr11:34,764,053...34,792,446
Ensembl chr11:34,764,721...34,791,993
JBrowse link
G Wdr47 WD repeat domain 47 decreases expression ISO Win 55212-2 results in decreased expression of WDR47 mRNA CTD PMID:12237329 NCBI chr 2:211,380,894...211,441,817
Ensembl chr 2:211,381,036...211,441,815
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO Win 55212-2 results in decreased expression of XIAP protein CTD PMID:30776504 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Znrf1 zinc and ring finger 1 increases expression ISO Win 55212-2 results in increased expression of ZNRF1 mRNA CTD PMID:12237329 NCBI chr19:43,750,205...43,834,962
Ensembl chr19:43,750,278...43,832,878
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        pharmacological role 18847
          agonist 18237
            cannabinoid receptor agonist 474
              cannabinoid 474
                endocannabinoid + 74
                phytocannabinoid + 350
                synthetic cannabinoid + 120
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            heteroorganic entity 19217
                              organochalcogen compound 18922
                                organooxygen compound 18846
                                  cannabinoid 474
                                    endocannabinoid + 74
                                    phytocannabinoid + 350
                                    synthetic cannabinoid + 120
paths to the root