Lcp1 (lymphocyte cytosolic protein 1) - Rat Genome Database

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Gene: Lcp1 (lymphocyte cytosolic protein 1) Rattus norvegicus
Analyze
Symbol: Lcp1
Name: lymphocyte cytosolic protein 1
RGD ID: 1308288
Description: Predicted to enable several functions, including GTPase binding activity; actin filament binding activity; and integrin binding activity. Involved in animal organ regeneration. Predicted to be located in several cellular components, including focal adhesion; podosome; and ruffle. Predicted to be active in actin filament; actin filament bundle; and cytoplasm. Predicted to colocalize with stress fiber. Human ortholog(s) of this gene implicated in nicotine dependence. Orthologous to human LCP1 (lymphocyte cytosolic protein 1); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC306071; plastin-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Candidate Gene For: Bmd62
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81556,846,375 - 56,954,090 (+)NCBIGRCr8
mRatBN7.21550,443,300 - 50,544,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,488,149 - 50,544,680 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1554,630,232 - 54,686,870 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01555,748,540 - 55,805,188 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01552,580,535 - 52,637,056 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,170,566 - 57,277,811 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,221,292 - 57,277,811 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01560,888,052 - 60,988,851 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,034,457 - 56,091,880 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11556,050,236 - 56,107,660 (+)NCBI
Celera1550,120,119 - 50,176,635 (+)NCBICelera
Cytogenetic Map15q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-palmitoylglycerol  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aniline  (EXP)
antirheumatic drug  (ISO)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
bathocuproine disulfonic acid  (ISO)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
buspirone  (EXP)
cadmium dichloride  (EXP)
calyculin a  (ISO)
cannabidiol  (ISO)
cantharidin  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
Cuprizon  (EXP)
curcumin  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dimethylarsinous acid  (ISO)
diuron  (ISO)
dorsomorphin  (ISO)
endosulfan  (EXP)
enzalutamide  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
hydroxyflutamide  (ISO)
indoles  (EXP)
ionomycin  (ISO)
KT 5926  (ISO)
lead diacetate  (ISO)
lidocaine  (EXP)
lithium chloride  (ISO)
methylarsonic acid  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nicotine  (ISO)
nimesulide  (EXP)
oxycodone  (EXP)
paracetamol  (EXP,ISO)
phenylmercury acetate  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
pyrrolidine dithiocarbamate  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sotorasib  (ISO)
tanespimycin  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trametinib  (ISO)
trichloroethene  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
tungsten  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Proteomic analysis of differential protein expression in early process of pancreatic regeneration in pancreatectomized rats. Yang M, etal., Acta Pharmacol Sin. 2006 May;27(5):568-78.
9. Substance dependence low-density whole genome association study in two distinct American populations. Yu Y, etal., Hum Genet. 2008 Jun;123(5):495-506. doi: 10.1007/s00439-008-0501-0. Epub 2008 Apr 26.
Additional References at PubMed
PMID:2111166   PMID:7655078   PMID:11591653   PMID:12477932   PMID:14756805   PMID:16502470   PMID:16636079   PMID:17294403   PMID:19056867   PMID:20183869   PMID:20458337   PMID:21922118  
PMID:22664934   PMID:23533145   PMID:24236012   PMID:24337748   PMID:33450132   PMID:36574182  


Genomics

Comparative Map Data
Lcp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81556,846,375 - 56,954,090 (+)NCBIGRCr8
mRatBN7.21550,443,300 - 50,544,682 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1550,488,149 - 50,544,680 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1554,630,232 - 54,686,870 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01555,748,540 - 55,805,188 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01552,580,535 - 52,637,056 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,170,566 - 57,277,811 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,221,292 - 57,277,811 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01560,888,052 - 60,988,851 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41556,034,457 - 56,091,880 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11556,050,236 - 56,107,660 (+)NCBI
Celera1550,120,119 - 50,176,635 (+)NCBICelera
Cytogenetic Map15q11NCBI
LCP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381346,125,923 - 46,182,177 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1346,125,920 - 46,211,871 (-)EnsemblGRCh38hg38GRCh38
GRCh371346,700,058 - 46,756,312 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361345,598,060 - 45,654,395 (-)NCBINCBI36Build 36hg18NCBI36
Build 341345,598,059 - 45,654,395NCBI
Celera1327,755,067 - 27,811,461 (-)NCBICelera
Cytogenetic Map13q14.13NCBI
HuRef1327,497,877 - 27,554,218 (-)NCBIHuRef
CHM1_11346,669,191 - 46,725,269 (-)NCBICHM1_1
T2T-CHM13v2.01345,347,305 - 45,403,192 (-)NCBIT2T-CHM13v2.0
Lcp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391475,368,570 - 75,468,282 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1475,368,541 - 75,468,282 (+)EnsemblGRCm39 Ensembl
GRCm381475,131,105 - 75,230,842 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,131,101 - 75,230,842 (+)EnsemblGRCm38mm10GRCm38
MGSCv371475,536,232 - 75,630,615 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361473,870,580 - 73,964,963 (+)NCBIMGSCv36mm8
Celera1472,636,371 - 72,732,832 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1439.63NCBI
Lcp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555183,814,840 - 3,891,299 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555183,815,181 - 3,863,440 (-)NCBIChiLan1.0ChiLan1.0
LCP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21445,180,206 - 45,266,387 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11336,234,410 - 36,320,594 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01326,820,846 - 26,906,916 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LCP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1224,955,453 - 5,059,654 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl224,992,347 - 5,059,636 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha224,965,424 - 5,047,265 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0225,070,372 - 5,176,432 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl225,123,064 - 5,175,065 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1224,852,728 - 4,958,773 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0224,916,029 - 5,022,003 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0224,921,102 - 5,027,186 (+)NCBIUU_Cfam_GSD_1.0
Lcp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945156,224,062 - 156,314,492 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936857646,118 - 698,035 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936857646,363 - 726,338 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LCP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,126,539 - 21,223,550 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11121,126,504 - 21,223,543 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21121,535,029 - 21,685,279 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LCP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1324,182,086 - 24,238,746 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl324,182,076 - 24,238,651 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605719,776,506 - 19,834,713 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lcp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247488,779,395 - 8,835,500 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247488,740,563 - 8,833,091 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lcp1
550 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:594
Count of miRNA genes:266
Interacting mature miRNAs:329
Transcripts:ENSRNOT00000014502
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat

Markers in Region
D15Mgh2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,531,797 - 50,531,936 (+)MAPPERmRatBN7.2
Rnor_6.01557,264,937 - 57,265,073NCBIRnor6.0
Rnor_5.01560,975,977 - 60,976,113UniSTSRnor5.0
RGSC_v3.41556,079,087 - 56,079,224RGDRGSC3.4
RGSC_v3.41556,079,088 - 56,079,224UniSTSRGSC3.4
RGSC_v3.11556,094,867 - 56,095,004RGD
Celera1550,163,764 - 50,163,900UniSTS
Cytogenetic Map15q11UniSTS
RH128715  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,544,425 - 50,544,605 (+)MAPPERmRatBN7.2
Rnor_6.01557,277,555 - 57,277,734NCBIRnor6.0
Rnor_5.01560,988,595 - 60,988,774UniSTSRnor5.0
RGSC_v3.41556,091,626 - 56,091,805UniSTSRGSC3.4
Celera1550,176,381 - 50,176,560UniSTS
Cytogenetic Map15q11UniSTS
BI273777  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21550,543,552 - 50,543,665 (+)MAPPERmRatBN7.2
Rnor_6.01557,276,682 - 57,276,794NCBIRnor6.0
Rnor_5.01560,987,722 - 60,987,834UniSTSRnor5.0
RGSC_v3.41556,090,753 - 56,090,865UniSTSRGSC3.4
Celera1550,175,508 - 50,175,620UniSTS
Cytogenetic Map15q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 20 48 33 19 33 3 3 45 35 35 11 3
Low 23 9 8 8 5 8 29 6 5
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000014502   ⟹   ENSRNOP00000014502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1550,488,149 - 50,544,680 (+)Ensembl
Rnor_6.0 Ensembl1557,221,292 - 57,277,809 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082191   ⟹   ENSRNOP00000071263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1550,508,815 - 50,544,680 (+)Ensembl
Rnor_6.0 Ensembl1557,241,968 - 57,277,811 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094863   ⟹   ENSRNOP00000092952
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1550,488,149 - 50,544,680 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105314   ⟹   ENSRNOP00000083584
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1550,508,815 - 50,544,680 (+)Ensembl
RefSeq Acc Id: NM_001012044   ⟹   NP_001012044
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,897,571 - 56,954,088 (+)NCBI
mRatBN7.21550,488,149 - 50,544,680 (+)NCBI
Rnor_6.01557,221,292 - 57,277,809 (+)NCBI
Rnor_5.01560,888,052 - 60,988,851 (+)NCBI
RGSC_v3.41556,034,457 - 56,091,880 (+)RGD
Celera1550,120,119 - 50,176,635 (+)RGD
Sequence:
RefSeq Acc Id: XM_006252319   ⟹   XP_006252381
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,895,449 - 56,954,090 (+)NCBI
mRatBN7.21550,486,027 - 50,544,682 (+)NCBI
Rnor_6.01557,219,117 - 57,277,811 (+)NCBI
Rnor_5.01560,888,052 - 60,988,851 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063274316   ⟹   XP_063130386
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81556,846,375 - 56,954,090 (+)NCBI
RefSeq Acc Id: NP_001012044   ⟸   NM_001012044
- UniProtKB: Q5XI38 (UniProtKB/TrEMBL),   A0A8I6AGS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252381   ⟸   XM_006252319
- Peptide Label: isoform X1
- UniProtKB: Q5XI38 (UniProtKB/TrEMBL),   A0A8I6AGS0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071263   ⟸   ENSRNOT00000082191
RefSeq Acc Id: ENSRNOP00000014502   ⟸   ENSRNOT00000014502
RefSeq Acc Id: ENSRNOP00000083584   ⟸   ENSRNOT00000105314
RefSeq Acc Id: ENSRNOP00000092952   ⟸   ENSRNOT00000094863
RefSeq Acc Id: XP_063130386   ⟸   XM_063274316
- Peptide Label: isoform X1
Protein Domains
Calponin-homology (CH)   EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K014-F1-model_v2 AlphaFold A0A0G2K014 1-645 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699829
Promoter ID:EPDNEW_R10352
Type:initiation region
Name:Lcp1_1
Description:lymphocyte cytosolic protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01557,221,275 - 57,221,335EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308288 AgrOrtholog
BioCyc Gene G2FUF-13137 BioCyc
Ensembl Genes ENSRNOG00000010319 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014502 ENTREZGENE
  ENSRNOT00000014502.6 UniProtKB/TrEMBL
  ENSRNOT00000082191.2 UniProtKB/TrEMBL
  ENSRNOT00000094863.1 UniProtKB/TrEMBL
  ENSRNOT00000105314.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.418.10 UniProtKB/TrEMBL
  EF-hand UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7125327 IMAGE-MGC_LOAD
InterPro Actinin_actin-bd_CS UniProtKB/TrEMBL
  Calponin-like_dom_sf UniProtKB/TrEMBL
  Calponin_act_bd UniProtKB/TrEMBL
  EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca_bd UniProtKB/TrEMBL
  Fimbrin/Plastin UniProtKB/TrEMBL
KEGG Report rno:306071 UniProtKB/TrEMBL
MGC_CLONE MGC:95070 IMAGE-MGC_LOAD
NCBI Gene 306071 ENTREZGENE
PANTHER PLASTIN-2 UniProtKB/TrEMBL
  PTHR19961 UniProtKB/TrEMBL
Pfam EF_hand_5 UniProtKB/TrEMBL
  PF00307 UniProtKB/TrEMBL
PhenoGen Lcp1 PhenoGen
PROSITE ACTININ_1 UniProtKB/TrEMBL
  ACTININ_2 UniProtKB/TrEMBL
  EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
  PS50021 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010319 RatGTEx
SMART EFh UniProtKB/TrEMBL
  SM00033 UniProtKB/TrEMBL
Superfamily-SCOP Calponin-homology UniProtKB/TrEMBL
  SSF47473 UniProtKB/TrEMBL
UniProt A0A0G2K014_RAT UniProtKB/TrEMBL
  A0A8I6AGS0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G984_RAT UniProtKB/TrEMBL
  Q5XI38 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Lcp1  lymphocyte cytosolic protein 1  Lcp1_predicted  lymphocyte cytosolic protein 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Lcp1_predicted  lymphocyte cytosolic protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED