Foxc2 (forkhead box C2) - Rat Genome Database

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Gene: Foxc2 (forkhead box C2) Rattus norvegicus
Analyze
Symbol: Foxc2
Name: forkhead box C2
RGD ID: 621703
Description: Enables DNA binding activity. Predicted to be involved in several processes, including insulin receptor signaling pathway; negative regulation of cold-induced thermogenesis; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including cell surface receptor signaling pathway; circulatory system development; and kidney development. Predicted to be located in nuclear body. Human ortholog(s) of this gene implicated in several diseases, including lymphedema; lymphedema-distichiasis syndrome; obesity; ptosis; and type 2 diabetes mellitus. Orthologous to human FOXC2 (forkhead box C2); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; alpha-Zearalanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: BF-3; brain factor 3; Fkh14; Fkhl14; forkhead box C2 (MFH-1 mesenchyme forkhead 1); forkhead box C2 (MFH-1, mesenchyme forkhead 1); forkhead box protein C2; HFH-BF-3; Hfhbf3
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81966,094,718 - 66,097,420 (+)NCBIGRCr8
mRatBN7.21949,186,034 - 49,188,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1949,185,662 - 49,188,737 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1955,977,317 - 55,980,018 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01956,661,030 - 56,663,732 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01958,875,485 - 58,878,187 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01953,044,379 - 53,047,081 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1953,044,379 - 53,047,081 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,788,037 - 63,790,739 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11228,513,040 - 228,513,088 (-)NCBI
Celera1948,432,333 - 48,435,035 (+)NCBICelera
Cytogenetic Map19q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure morphogenesis  (IBA)
apoptotic process involved in outflow tract morphogenesis  (ISO)
artery morphogenesis  (ISO)
blood vessel development  (ISO)
blood vessel diameter maintenance  (ISO)
blood vessel remodeling  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
camera-type eye development  (ISO)
cardiac muscle cell proliferation  (ISO)
cell differentiation  (IBA)
cell population proliferation  (ISO)
collagen fibril organization  (ISO)
embryonic cranial skeleton morphogenesis  (ISO)
embryonic heart tube development  (ISO)
embryonic skeletal system morphogenesis  (ISO)
embryonic viscerocranium morphogenesis  (ISO)
glomerular endothelium development  (ISO)
glomerular mesangial cell development  (ISO)
heart development  (ISO)
heart morphogenesis  (ISO)
insulin receptor signaling pathway  (ISO)
kidney development  (ISO)
lymph vessel development  (ISO)
lymphangiogenesis  (ISO)
metanephros development  (ISO)
negative regulation of apoptotic process involved in outflow tract morphogenesis  (ISO)
negative regulation of cold-induced thermogenesis  (ISO,ISS)
negative regulation of transcription by RNA polymerase II  (ISO)
neural crest cell development  (ISO)
Notch signaling pathway  (ISO)
ossification  (ISO)
paraxial mesoderm formation  (ISO)
paraxial mesodermal cell fate commitment  (ISO)
podocyte differentiation  (ISO)
positive regulation of cell adhesion mediated by integrin  (ISO)
positive regulation of cell migration involved in sprouting angiogenesis  (ISO)
positive regulation of DNA-templated transcription  (ISO)
positive regulation of endothelial cell migration  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO,ISS)
positive regulation of vascular wound healing  (ISO)
regulation of DNA-templated transcription  (TAS)
regulation of organ growth  (ISO)
regulation of transcription by RNA polymerase II  (IBA)
response to hormone  (ISO)
skeletal system development  (ISO)
somitogenesis  (ISO)
ureteric bud development  (ISO)
vascular endothelial growth factor receptor signaling pathway  (ISO)
ventricular cardiac muscle tissue morphogenesis  (ISO)

Cellular Component
nuclear body  (IEA,ISO)
nucleoplasm  (ISO)
nucleus  (ISO)

References

References - curated
# Reference Title Reference Citation
1. The FOXC2 C-512T polymorphism is associated with obesity and dyslipidemia. Carlsson E, etal., Obes Res. 2004 Nov;12(11):1738-43.
2. FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance. Cederberg A, etal., Cell. 2001 Sep 7;106(5):563-73.
3. Identification of nine tissue-specific transcription factors of the hepatocyte nuclear factor 3/forkhead DNA-binding-domain family. Clevidence DE, etal., Proc Natl Acad Sci U S A 1993 May 1;90(9):3948-52.
4. Truncating mutations in FOXC2 cause multiple lymphedema syndromes. Finegold DN, etal., Hum Mol Genet. 2001 May 15;10(11):1185-9.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. Transcriptional genomics associates FOX transcription factors with human heart failure. Hannenhalli S, etal., Circulation. 2006 Sep 19;114(12):1269-76. Epub 2006 Sep 4.
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Systematic search for single nucleotide polymorphisms in the FOXC2 gene: the absence of evidence for the association of three frequent single nucleotide polymorphisms and four common haplotypes with Japanese type 2 diabetes. Osawa H, etal., Diabetes. 2003 Feb;52(2):562-7.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. FOXC2 mRNA Expression and a 5' untranslated region polymorphism of the gene are associated with insulin resistance. Ridderstrale M, etal., Diabetes. 2002 Dec;51(12):3554-60.
14. A novel frameshift mutation of FOXC2 gene in a family with hereditary lymphedema-distichiasis syndrome associated with renal disease and diabetes mellitus. Yildirim-Toruner C, etal., Am J Med Genet A. 2004 Dec 15;131(3):281-6.
Additional References at PubMed
PMID:8325367   PMID:9106663   PMID:9169153   PMID:9409679   PMID:10364424   PMID:10479458   PMID:10704385   PMID:10767326   PMID:11562355   PMID:11943768   PMID:12114478   PMID:15664398  
PMID:16081467   PMID:16456100   PMID:16498405   PMID:16678147   PMID:16839542   PMID:18187037   PMID:18579532   PMID:19170063   PMID:20956529   PMID:21457232   PMID:25609649   PMID:26824865  
PMID:33423166   PMID:34739190  


Genomics

Comparative Map Data
Foxc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81966,094,718 - 66,097,420 (+)NCBIGRCr8
mRatBN7.21949,186,034 - 49,188,736 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1949,185,662 - 49,188,737 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1955,977,317 - 55,980,018 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01956,661,030 - 56,663,732 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01958,875,485 - 58,878,187 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01953,044,379 - 53,047,081 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1953,044,379 - 53,047,081 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01963,788,037 - 63,790,739 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11228,513,040 - 228,513,088 (-)NCBI
Celera1948,432,333 - 48,435,035 (+)NCBICelera
Cytogenetic Map19q12NCBI
FOXC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381686,566,829 - 86,569,728 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1686,566,829 - 86,569,728 (+)EnsemblGRCh38hg38GRCh38
GRCh371686,600,435 - 86,603,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361685,158,443 - 85,159,948 (+)NCBINCBI36Build 36hg18NCBI36
Build 341685,158,442 - 85,159,948NCBI
Celera1670,901,820 - 70,903,503 (+)NCBICelera
Cytogenetic Map16q24.1NCBI
HuRef1672,340,749 - 72,342,345 (+)NCBIHuRef
CHM1_11688,012,585 - 88,014,267 (+)NCBICHM1_1
T2T-CHM13v2.01692,635,146 - 92,638,044 (+)NCBIT2T-CHM13v2.0
Foxc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398121,842,910 - 121,845,634 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8121,842,910 - 121,845,634 (+)EnsemblGRCm39 Ensembl
GRCm388121,116,171 - 121,118,895 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8121,116,171 - 121,118,895 (+)EnsemblGRCm38mm10GRCm38
MGSCv378123,640,071 - 123,642,795 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368124,002,560 - 124,004,872 (+)NCBIMGSCv36mm8
Celera8125,334,251 - 125,336,975 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map870.33NCBI
FOXC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21896,322,973 - 96,325,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan116102,240,170 - 102,243,107 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01667,237,476 - 67,239,545 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11686,569,509 - 86,571,878 (+)NCBIpanpan1.1PanPan1.1panPan2
FOXC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1566,234,336 - 66,296,007 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl566,294,176 - 66,295,693 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha566,246,461 - 66,254,587 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0566,455,805 - 66,464,138 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1566,479,102 - 66,487,010 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0566,314,300 - 66,322,205 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0566,727,335 - 66,735,464 (-)NCBIUU_Cfam_GSD_1.0
Foxc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934926,482,456 - 26,485,324 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366412,236,873 - 2,238,375 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366412,236,224 - 2,238,501 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FOXC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl62,552,862 - 2,554,367 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.162,552,141 - 2,555,041 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.262,756,138 - 2,761,356 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FOXC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1571,951,980 - 71,955,021 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl571,952,632 - 71,954,134 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660473,750,917 - 3,753,843 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Foxc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247462,632,619 - 2,634,085 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247462,632,547 - 2,634,867 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Foxc2
5 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:73
Count of miRNA genes:64
Interacting mature miRNAs:67
Transcripts:ENSRNOT00000072369
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum insulin level (CMO:0000358)193383821455283146Rat
1358200Insglur2Insulin/glucose ratio QTL 24.1blood glucose amount (VT:0000188)serum glucose level (CMO:0000543)193383821455283146Rat
5135224Leukc1Leukocyte quantity QTL 1eosinophil quantity (VT:0002602)blood eosinophil count (CMO:0000033)194434021455283277Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 4 18 11
Low 28 8 6 6 66 17 17
Below cutoff 2 11 15 8 4 8 6 8 8 11 11 6

Sequence


RefSeq Acc Id: ENSRNOT00000072369   ⟹   ENSRNOP00000065254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1949,185,662 - 49,188,737 (+)Ensembl
Rnor_6.0 Ensembl1953,044,379 - 53,047,081 (+)Ensembl
RefSeq Acc Id: NM_001101680   ⟹   NP_001095150
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81966,094,718 - 66,097,420 (+)NCBI
mRatBN7.21949,186,034 - 49,188,736 (+)NCBI
Rnor_6.01953,044,379 - 53,047,081 (+)NCBI
Rnor_5.01963,788,037 - 63,790,739 (+)NCBI
Celera1948,432,333 - 48,435,035 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001095150 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41320 (Get FASTA)   NCBI Sequence Viewer  
  EDL92716 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000065254
  ENSRNOP00000065254.1
  ENSRNOP00055030974
  ENSRNOP00060034711
  ENSRNOP00065008093
GenBank Protein Q63246 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001095150   ⟸   NM_001101680
- UniProtKB: M0R736 (UniProtKB/Swiss-Prot),   Q63246 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000065254   ⟸   ENSRNOT00000072369

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63246-F1-model_v2 AlphaFold Q63246 1-494 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701190
Promoter ID:EPDNEW_R11713
Type:initiation region
Name:Foxc2_1
Description:forkhead box C2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01953,044,357 - 53,044,417EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621703 AgrOrtholog
BioCyc Gene G2FUF-5453 BioCyc
Ensembl Genes ENSRNOG00000047446 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055022074 UniProtKB/Swiss-Prot
  ENSRNOG00060024189 UniProtKB/Swiss-Prot
  ENSRNOG00065007070 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000072369 ENTREZGENE
  ENSRNOT00000072369.2 UniProtKB/Swiss-Prot
  ENSRNOT00055037933 UniProtKB/Swiss-Prot
  ENSRNOT00060041857 UniProtKB/Swiss-Prot
  ENSRNOT00065011019 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
InterPro Fork_head_dom UniProtKB/Swiss-Prot
  FOXC1/C2-like_FH UniProtKB/Swiss-Prot
  TF_fork_head_CS_1 UniProtKB/Swiss-Prot
  TF_fork_head_CS_2 UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
KEGG Report rno:171356 UniProtKB/Swiss-Prot
NCBI Gene 171356 ENTREZGENE
PANTHER FORKHEAD BOX PROTEIN UniProtKB/Swiss-Prot
  FORKHEAD BOX PROTEIN C2 UniProtKB/Swiss-Prot
Pfam Forkhead UniProtKB/Swiss-Prot
PhenoGen Foxc2 PhenoGen
PRINTS FORKHEAD UniProtKB/Swiss-Prot
PROSITE FORK_HEAD_1 UniProtKB/Swiss-Prot
  FORK_HEAD_2 UniProtKB/Swiss-Prot
  FORK_HEAD_3 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047446 RatGTEx
  ENSRNOG00055022074 RatGTEx
  ENSRNOG00060024189 RatGTEx
  ENSRNOG00065007070 RatGTEx
SMART SM00339 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot
UniProt FOXC2_RAT UniProtKB/Swiss-Prot
  M0R736 ENTREZGENE
  Q63246 ENTREZGENE
UniProt Secondary M0R736 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Foxc2  forkhead box C2    forkhead box C2 (MFH-1, mesenchyme forkhead 1)  Name updated 1299863 APPROVED
2002-08-07 Foxc2  forkhead box C2 (MFH-1, mesenchyme forkhead 1)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains forkhead DNA-binding domain recognizes its cognate DNA binding site as a monomer 632667
gene_expression mRNA expressed in liver, brain, kidney, lung, and intestine 632667
gene_homology shares homology with Drosophila homeotic protein forkhead (fkh) 632667
gene_product member of hepatocyte nuclear transcription factor (HNF) family 632667