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Gene: Mef2c (myocyte enhancer factor 2C) Rattus norvegicus
Symbol: Mef2c
Name: myocyte enhancer factor 2C
RGD ID: 1563119
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in several processes, including cellular response to retinoic acid; dentate gyrus development; and transdifferentiation. Localizes to nucleus and sarcomere. Used to study myocardial infarction. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 20. Orthologous to human MEF2C (myocyte enhancer factor 2C); PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC499497; LOC685671; myocyte-specific enhancer factor 2C; RGD1563119; similar to MADS box transcription enhancer factor 2, polypeptide C (myocyte enhancer factor 2C); similar to myocyte enhancer factor 2C
Homo sapiens (human) : MEF2C (myocyte enhancer factor 2C)  HGNC  Alliance
Mus musculus (house mouse) : Mef2c (myocyte enhancer factor 2C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mef2c (myocyte enhancer factor 2C)
Pan paniscus (bonobo/pygmy chimpanzee) : MEF2C (myocyte enhancer factor 2C)
Canis lupus familiaris (dog) : MEF2C (myocyte enhancer factor 2C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mef2c (myocyte enhancer factor 2C)
Sus scrofa (pig) : MEF2C (myocyte enhancer factor 2C)
Chlorocebus sabaeus (African green monkey) : MEF2C (myocyte enhancer factor 2C)
Heterocephalus glaber (naked mole-rat) : Mef2c (myocyte enhancer factor 2C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0211,658,534 - 11,822,788 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl211,658,568 - 11,822,787 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0211,521,053 - 11,684,949 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4212,331,078 - 12,346,520 (-)NCBIRGSC3.4rn4RGSC3.4
Celera210,288,159 - 10,449,731 (+)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Mef2c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1563119
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.