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Gene: Pld1 (phospholipase D1) Rattus norvegicus
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Symbol: Pld1
Name: phospholipase D1
Description: Exhibits phospholipase D activity. Involved in phospholipid metabolic process; positive regulation of cell migration; and response to peptide hormone. Localizes to several cellular components, including the Golgi cisterna; lamellipodium; and vesicle. Biomarker of visual epilepsy. Orthologous to human PLD1 (phospholipase D1); PARTICIPATES IN mTOR signaling pathway; ceramide signaling pathway; endocytosis pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-octadec-9-enoylglycero-3-phosphate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: choline phosphatase 1; Phoshpolipase D gene 1; Phoshpolipase D gene 1 probably with two splicing variants A and B; phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D gene 1; phospholipase D gene 1 probably with two splicing variants A and B; phospholipase D gene 1, probably with two splicing variants A and B; phospholipase D1, phosphatidylcholine-specific; PLD 1; Pld1a; Pld1b; Plda; Pldb; rPLD1
Orthologs:
Homo sapiens (human) : PLD1 (phospholipase D1)  HGNC  Alliance
Mus musculus (house mouse) : Pld1 (phospholipase D1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld1 (phospholipase D1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD1 (phospholipase D1)
Canis lupus familiaris (dog) : PLD1 (phospholipase D1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld1 (phospholipase D1)
Sus scrofa (pig) : PLD1 (phospholipase D1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02113,651,967 - 113,849,403 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02133,357,235 - 133,554,180 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42115,306,940 - 115,460,518 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12115,251,901 - 115,405,480 (+)NCBI
Celera2106,084,707 - 106,238,116 (+)NCBICelera
Cytogenetic Map2q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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Gene Ontology Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pld1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3349
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.