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Gene: Angpt2 (angiopoietin 2) Rattus norvegicus
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Symbol: Angpt2
Name: angiopoietin 2
Description: Predicted to have receptor tyrosine kinase binding activity. Involved in several processes, including animal organ regeneration; blood vessel development; and maternal process involved in female pregnancy. Localizes to several cellular components, including the cell projection; extracellular space; and nucleus. Used to study several diseases, including ischemia (multiple); membranoproliferative glomerulonephritis; portal hypertension; retinal disease (multiple); and uremia. Biomarker of several diseases, including Caroli disease; artery disease (multiple); gastric ulcer; glomerulonephritis (multiple); and retinal disease (multiple). Orthologous to human ANGPT2 (angiopoietin 2); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Agpt2; Ang-2; angiopoietin-2
Orthologs:
Homo sapiens (human) : ANGPT2 (angiopoietin 2)  HGNC  Alliance
Mus musculus (house mouse) : Angpt2 (angiopoietin 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Angpt2 (angiopoietin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ANGPT2 (angiopoietin 2)
Canis lupus familiaris (dog) : ANGPT2 (angiopoietin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Angpt2 (angiopoietin 2)
Sus scrofa (pig) : ANGPT2 (angiopoietin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01675,966,480 - 76,016,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,966,352 - 76,016,195 (+)Ensembl
Rnor_5.01675,572,301 - 75,621,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41675,891,757 - 75,942,255 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11675,934,743 - 75,941,749 (+)NCBI
Celera1668,933,847 - 68,984,314 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Angpt2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621861
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.