Angpt2 (angiopoietin 2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Angpt2 (angiopoietin 2) Ictidomys tridecemlineatus
Analyze
Symbol: Angpt2
Name: angiopoietin 2
RGD ID: 12497316
Description: ENCODES a protein that exhibits metal ion binding (inferred); receptor tyrosine kinase binding (inferred); INVOLVED IN angiogenesis (ortholog); animal organ regeneration (ortholog); blood vessel morphogenesis (ortholog); ASSOCIATED WITH adenocarcinoma (ortholog); Alcoholic Liver Diseases (ortholog); angiosarcoma (ortholog); FOUND IN cell projection (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: angiopoietin-2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049434,473,275 - 4,524,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366154,472,247 - 4,524,556 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366154,472,261 - 4,524,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Angpt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049434,473,275 - 4,524,605 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366154,472,247 - 4,524,556 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366154,472,261 - 4,524,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ANGPT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3886,499,632 - 6,563,245 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl86,499,632 - 6,563,409 (-)EnsemblGRCh38hg38GRCh38
GRCh3786,357,153 - 6,420,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3686,347,601 - 6,408,170 (-)NCBINCBI36Build 36hg18NCBI36
Build 3486,347,600 - 6,408,172NCBI
Celera86,334,650 - 6,398,296 (-)NCBICelera
Cytogenetic Map8p23.1NCBI
HuRef86,139,162 - 6,202,785 (-)NCBIHuRef
CHM1_186,445,906 - 6,509,954 (-)NCBICHM1_1
T2T-CHM13v2.086,254,102 - 6,317,682 (-)NCBIT2T-CHM13v2.0
Angpt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39818,740,279 - 18,791,578 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl818,740,279 - 18,791,578 (-)EnsemblGRCm39 Ensembl
GRCm38818,690,263 - 18,741,562 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl818,690,263 - 18,741,562 (-)EnsemblGRCm38mm10GRCm38
MGSCv37818,691,337 - 18,741,551 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36818,691,314 - 18,741,528 (-)NCBIMGSCv36mm8
Celera818,824,534 - 18,875,113 (-)NCBICelera
Cytogenetic Map8A1.3NCBI
cM Map810.3NCBI
Angpt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81677,790,760 - 77,841,241 (+)NCBIGRCr8
mRatBN7.21671,088,364 - 71,138,805 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1671,088,364 - 71,138,804 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1676,365,217 - 76,415,702 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01679,811,900 - 79,862,566 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01675,061,325 - 75,111,991 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01675,966,480 - 76,016,147 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1675,966,352 - 76,016,195 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01675,572,301 - 75,621,968 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41675,891,757 - 75,942,255 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11675,934,743 - 75,941,749 (+)NCBI
Celera1668,933,847 - 68,984,314 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
Angpt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540354,139,823 - 54,195,032 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540354,139,823 - 54,193,740 (+)NCBIChiLan1.0ChiLan1.0
ANGPT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2721,294,413 - 21,380,483 (-)NCBINHGRI_mPanPan1-v2
Mhudiblu_PPA_v08718,367 - 782,534 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.186,506,012 - 6,566,915 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl86,506,014 - 6,566,915 (-)Ensemblpanpan1.1panPan2
ANGPT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11658,404,049 - 58,458,344 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1658,405,259 - 58,457,701 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1653,935,215 - 53,987,886 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01657,592,625 - 57,645,271 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1657,592,730 - 57,645,741 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11658,549,239 - 58,616,758 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01655,601,814 - 55,654,409 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01655,977,188 - 56,030,293 (+)NCBIUU_Cfam_GSD_1.0
ANGPT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1537,544,707 - 37,599,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11537,544,177 - 37,600,925 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21542,687,923 - 42,787,653 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ANGPT2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.186,283,619 - 6,345,320 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl86,280,584 - 6,344,729 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605448,397,826 - 48,458,677 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Angpt2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248614,457,158 - 4,509,623 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248614,457,519 - 4,510,035 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005334345 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSSTOT00000003106   ⟹   ENSSTOP00000002777
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
SpeTri2.0 EnsemblNW_0049366154,472,247 - 4,524,556 (-)Ensembl
RefSeq Acc Id: XM_005334345   ⟹   XP_005334402
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244049434,473,275 - 4,524,605 (-)NCBI
SpeTri2.0NW_0049366154,472,261 - 4,524,537 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005334402 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000002777.3
GenBank Protein KAG3294230 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005334402   ⟸   XM_005334345
- UniProtKB: I3M1P3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSTOP00000002777   ⟸   ENSSTOT00000003106
Protein Domains
Fibrinogen C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000003106 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000003106.3 UniProtKB/TrEMBL
Gene3D-CATH 3.90.215.10 UniProtKB/TrEMBL
  Gamma-fibrinogen Carboxyl Terminal Fragment, domain 2 UniProtKB/TrEMBL
InterPro Fibrinogen-like_C UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_1 UniProtKB/TrEMBL
  Fibrinogen_a/b/g_C_dom UniProtKB/TrEMBL
  Fibrinogen_CS UniProtKB/TrEMBL
NCBI Gene Angpt2 ENTREZGENE
PANTHER FIBRINOGEN/TENASCIN/ANGIOPOEITIN UniProtKB/TrEMBL
  PTHR19143:SF199 UniProtKB/TrEMBL
Pfam Fibrinogen_C UniProtKB/TrEMBL
PROSITE FIBRINOGEN_C_1 UniProtKB/TrEMBL
  FIBRINOGEN_C_2 UniProtKB/TrEMBL
SMART FBG UniProtKB/TrEMBL
Superfamily-SCOP SSF56496 UniProtKB/TrEMBL
UniProt I3M1P3 ENTREZGENE, UniProtKB/TrEMBL