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Gene: Cnr1 (cannabinoid receptor 1) Rattus norvegicus
Symbol: Cnr1
Name: cannabinoid receptor 1
Description: Exhibits cannabinoid receptor activity and drug binding activity. Involved in several processes, including positive regulation of acute inflammatory response; regulation of secretion by cell; and response to alkaloid. Localizes to membrane raft and plasma membrane. Colocalizes with intracellular membrane-bounded organelle. Used to study several diseases, including diabetic neuropathy; hypertension; impotence; obesity; and peptic ulcer disease. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in obesity; schizophrenia; and type 2 diabetes mellitus. Orthologous to human CNR1 (cannabinoid receptor 1); PARTICIPATES IN N-cadherin signaling pathway; INTERACTS WITH (+)-pilocarpine; 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: brain-type cannabinoid receptor; cannabinoid receptor 1 (brain); CB-R; CB1; SKR6R
Homo sapiens (human) : CNR1 (cannabinoid receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Cnr1 (cannabinoid receptor 1 (brain))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cnr1 (cannabinoid receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CNR1 (cannabinoid receptor 1)
Canis lupus familiaris (dog) : CNR1 (cannabinoid receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cnr1 (cannabinoid receptor 1)
Sus scrofa (pig) : CNR1 (cannabinoid receptor 1)
Chlorocebus sabaeus (African green monkey) : CNR1 (cannabinoid receptor 1)
Heterocephalus glaber (naked mole-rat) : Cnr1 (cannabinoid receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0549,307,584 - 49,333,064 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl549,311,030 - 49,333,056 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0553,878,619 - 53,904,013 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4550,427,173 - 50,445,471 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1550,427,351 - 50,445,650 (+)NCBI
Celera547,168,709 - 47,190,724 (+)NCBICelera
Cytogenetic Map5q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Cnr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2369
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.