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Gene: Tnfaip3 (TNF alpha induced protein 3) Rattus norvegicus
Symbol: Tnfaip3
Name: TNF alpha induced protein 3
Description: Predicted to have several functions, including K63-linked polyubiquitin modification-dependent protein binding activity; enzyme binding activity; and ubiquitinyl hydrolase activity. Predicted to be involved in several processes, including negative regulation of macromolecule metabolic process; negative regulation of signal transduction; and protein modification by small protein conjugation or removal. Predicted to localize to cytoplasm and nucleus. Orthologous to human TNFAIP3 (TNF alpha induced protein 3); PARTICIPATES IN nuclear factor kappa B signaling pathway; tumor necrosis factor mediated signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; acrylamide; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Also known as: LOC683206; similar to Tumor necrosis factor, alpha-induced protein 3 (Putative DNA binding protein A20) (Zinc finger protein A20); tumor necrosis factor alpha-induced protein 3; tumor necrosis factor, alpha-induced protein 3
Homo sapiens (human) : TNFAIP3 (TNF alpha induced protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Tnfaip3 (tumor necrosis factor, alpha-induced protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfaip3 (TNF alpha induced protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFAIP3 (TNF alpha induced protein 3)
Canis lupus familiaris (dog) : TNFAIP3 (TNF alpha induced protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfaip3 (TNF alpha induced protein 3)
Sus scrofa (pig) : TNFAIP3 (TNF alpha induced protein 3)
Chlorocebus sabaeus (African green monkey) : TNFAIP3 (TNF alpha induced protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0114,401,103 - 14,416,369 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl114,402,913 - 14,412,807 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0115,952,235 - 15,963,951 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera112,159,804 - 12,174,919 (-)NCBICelera
Cytogenetic Map1p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Tnfaip3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1589275
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.