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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619800
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Vegfc
Name: vascular endothelial growth factor C
Acc ID: CHEBI:191854
Term: arachidonyl-2'-chloroethylamide
Definition: A fatty amide obtained by the formal condensation of arachidonic acid with 2-chloroethanamine. It is a potent agonist of the CB1 receptor (Ki = 1.4 nM) and also has a low affinity for the CB2 receptor (Ki = 3100 nM).
Chemical ID: MESH:C119325
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Vegfcmultiple interactionsISOVEGFC (Homo sapiens)6480464CTDAM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]PMID:26467187
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