Plpp3 (phospholipid phosphatase 3)

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Gene: Plpp3 (phospholipid phosphatase 3) Rattus norvegicus

Analyze

Symbol:

Plpp3

Name:

phospholipid phosphatase 3

RGD ID:

620454

Description:

Predicted to enable integrin binding activity and lipid phosphatase activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by integrin; protein stabilization; and sphingolipid metabolic process. Predicted to act upstream of or within several processes, including Bergmann glial cell differentiation; positive regulation of peptidyl-tyrosine phosphorylation; and regulation of signal transduction. Located in endoplasmic reticulum membrane. Orthologous to human PLPP3 (phospholipid phosphatase 3); PARTICIPATES IN ether lipid metabolic pathway; ether lipid metabolic pathway; Fc gamma receptor mediated signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

differentially expressed in rat intestine; differentially expressed in rat intestine 42; Dri42; ER transmembrane protein Dri 42; lipid phosphate phosphohydrolase 3; PAP-2b; PAP2-beta; PAP2b; phosphatidate phosphohydrolase type 2b; phosphatidic acid phosphatase 2b; phosphatidic acid phosphatase type 2B; Ppap2b

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	PLPP3 (phospholipid phosphatase 3)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Plpp3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Plpp3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	PLPP3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	PLPP3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Plpp3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	PLPP3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	PLPP3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Plpp3 (phospholipid phosphatase 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Plpp3 (phospholipid phosphatase 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	PLPP3 (phospholipid phosphatase 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	plpp3 (phospholipid phosphatase 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11425	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Caenorhabditis elegans (roundworm):	plpp-1.1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11426	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG11437	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	CG11438	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	wun	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	laza	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	wun2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	plpp3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	119,927,085 - 120,002,206 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	119,927,085 - 120,002,205 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	122,548,651 - 122,624,021 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	124,271,713 - 124,347,083 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	124,322,955 - 124,398,328 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	124,690,214 - 124,765,499 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	124,690,214 - 124,765,498 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	128,551,196 - 128,626,138 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	126,121,416 - 126,197,099 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	126,126,641 - 126,202,324 (+)	NCBI
Celera	5	118,477,102 - 118,551,973 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Cardiomegaly (ISO)

coronary artery disease (ISO)

genetic disease (ISO)

Ventricular Dysfunction, Left (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2-amino-2-deoxy-D-glucopyranose (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

6alpha-methylprednisolone (ISO)

acetamide (EXP)

aflatoxin B1 (ISO)

aldehydo-D-glucosamine (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

ATP (ISO)

azathioprine (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

beta-D-glucosamine (EXP)

bisphenol A (EXP,ISO)

Bisphenol B (ISO)

bisphenol F (ISO)

buspirone (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

cadmium sulfate (ISO)

calyculin a (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

chloroprene (EXP)

choline (ISO)

cisplatin (ISO)

clofibric acid (EXP)

cobalt dichloride (EXP)

cocaine (EXP)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

diallyl disulfide (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dieldrin (EXP)

dioxygen (ISO)

diuron (EXP)

divanadium pentaoxide (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

endosulfan (EXP)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

finasteride (EXP)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

furan (EXP)

gamma-hexachlorocyclohexane (EXP)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

graphite (EXP)

hydrogen chloride (ISO)

hydrogen peroxide (ISO)

indometacin (ISO)

isoflavones (ISO)

isotretinoin (ISO)

L-methionine (ISO)

lead diacetate (ISO)

metacetamol (ISO)

methapyrilene (EXP)

methimazole (EXP)

methotrexate (ISO)

methylmercury chloride (ISO)

N-nitrosodiethylamine (EXP)

nefazodone (EXP)

nickel dichloride (EXP,ISO)

nimesulide (EXP)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

pirinixic acid (EXP,ISO)

piroxicam (ISO)

potassium chromate (ISO)

prednisolone (ISO)

pregnenolone 16alpha-carbonitrile (EXP)

progesterone (ISO)

propiconazole (EXP,ISO)

raloxifene (ISO)

Securinine (ISO)

selenium atom (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

sodium arsenite (ISO)

sodium aurothiomalate (ISO)

sodium dichromate (EXP)

sodium dodecyl sulfate (ISO)

sodium fluoride (ISO)

succimer (ISO)

sulfadimethoxine (EXP)

tamoxifen (ISO)

testosterone enanthate (ISO)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

topotecan (EXP)

triadimefon (EXP)

triclosan (ISO)

triphenyl phosphate (EXP)

Triptolide (EXP)

troglitazone (ISO)

trovafloxacin (EXP)

tunicamycin (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

vitamin E (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

Bergmann glial cell differentiation (ISO)

blood vessel development (ISO)

cell adhesion (ISO)

cell-cell adhesion (ISO)

cell-cell adhesion mediated by integrin (ISO,ISS)

ceramide metabolic process (ISO,ISS)

gastrulation with mouth forming second (ISO)

homotypic cell-cell adhesion (ISO)

integrin-mediated signaling pathway (ISO,ISS)

negative regulation of protein phosphorylation (ISO)

phospholipid dephosphorylation (IBA,ISO,ISS)

phospholipid metabolic process (IBA,IEA,ISO,ISS)

positive regulation of cell-cell adhesion (ISO)

positive regulation of endothelial cell migration (ISO)

positive regulation of peptidyl-tyrosine phosphorylation (ISO)

protein stabilization (ISO)

regulation of sphingolipid mediated signaling pathway (ISO)

regulation of Wnt signaling pathway (ISO)

retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (ISO,ISS)

signal transduction (IBA)

sphingosine metabolic process (ISO,ISS)

wound healing (ISO)

Cellular Component

basolateral plasma membrane (ISO)

endoplasmic reticulum exit site (ISO,ISS)

endoplasmic reticulum membrane (IDA)

endoplasmic reticulum-Golgi intermediate compartment membrane (ISO,ISS)

Golgi apparatus (ISO,ISS)

Golgi membrane (IEA)

membrane (IEA,ISO,ISS)

membrane raft (ISO,ISS)

plasma membrane (ISO)

trans-Golgi network (ISO,ISS)

Molecular Function

ceramide-1-phosphate phosphatase activity (ISO,ISS)

integrin binding (ISO,ISS)

lipid phosphatase activity (ISO)

phosphatidate phosphatase activity (IBA,ISO,ISS)

protein binding (ISO)

sphingosine-1-phosphate phosphatase activity (IBA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

ether lipid metabolic pathway (IEA)

Fc gamma receptor mediated signaling pathway (IEA)

glycerolipid metabolic pathway (IEA)

glycerophospholipid metabolic pathway (IEA)

sphingolipid metabolic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	The Dri 42 gene, whose expression is up-regulated during epithelial differentiation, encodes a novel endoplasmic reticulum resident transmembrane protein.	Barila D, etal., J Biol Chem 1996 Nov 22;271(47):29928-36.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:8055940	PMID:9305923	PMID:9705349	PMID:12660161	PMID:12925589	PMID:14527693	PMID:16099422	PMID:17005594	PMID:20123964	PMID:21319224	PMID:22871113	PMID:23376485
PMID:23591818

Genomics

Comparative Map Data

Plpp3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	5	119,927,085 - 120,002,206 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	119,927,085 - 120,002,205 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	122,548,651 - 122,624,021 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	124,271,713 - 124,347,083 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	124,322,955 - 124,398,328 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	124,690,214 - 124,765,499 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	124,690,214 - 124,765,498 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	128,551,196 - 128,626,138 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	126,121,416 - 126,197,099 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	126,126,641 - 126,202,324 (+)	NCBI
Celera	5	118,477,102 - 118,551,973 (+)	NCBI		Celera
Cytogenetic Map	5	q34	NCBI

PLPP3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	56,494,761 - 56,579,563 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	56,494,761 - 56,645,301 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	56,960,433 - 57,045,236 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	56,733,021 - 56,817,845 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	55,245,253 - 55,330,133 (-)	NCBI		Celera
Cytogenetic Map	1	p32.2	NCBI
HuRef	1	55,072,892 - 55,157,775 (-)	NCBI		HuRef
CHM1_1	1	57,072,622 - 57,160,617 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	56,373,591 - 56,458,441 (-)	NCBI		T2T-CHM13v2.0

Plpp3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	105,014,544 - 105,089,964 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	105,014,544 - 105,089,961 (+)	Ensembl		GRCm39 Ensembl
GRCm38	4	105,157,347 - 105,232,767 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	105,157,347 - 105,232,764 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	104,829,952 - 104,905,372 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	104,655,279 - 104,730,699 (+)	NCBI		MGSCv36	mm8
Celera	4	103,508,199 - 103,583,768 (+)	NCBI		Celera
Cytogenetic Map	4	C6	NCBI
cM Map	4	49.18	NCBI

Plpp3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955464	3,081,334 - 3,197,413 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955464	3,122,420 - 3,197,359 (+)	NCBI	ChiLan1.0	ChiLan1.0

PLPP3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	1	169,400,091 - 169,484,785 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	55,779,343 - 55,862,717 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	57,489,178 - 57,573,307 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	57,489,178 - 57,573,398 (-)	Ensembl	panpan1.1		panPan2

PLPP3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	52,924,443 - 53,006,298 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	52,923,833 - 53,005,493 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	52,992,430 - 53,074,349 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	53,112,365 - 53,194,538 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	53,112,379 - 53,194,536 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	53,055,985 - 53,137,860 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	53,001,878 - 53,083,760 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	53,386,869 - 53,468,888 (+)	NCBI		UU_Cfam_GSD_1.0

Plpp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	70,341,999 - 70,423,866 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936522	4,992,322 - 5,074,313 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936522	4,992,333 - 5,074,295 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

PLPP3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	155,800,678 - 155,894,912 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	155,800,838 - 155,894,919 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	143,642,088 - 143,734,081 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PLPP3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	76,382,041 - 76,466,497 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	76,382,079 - 76,477,847 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	40,825,335 - 40,909,946 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Plpp3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624862	3,550,968 - 3,627,058 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624862	3,550,498 - 3,627,061 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Plpp3
387 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	739
Count of miRNA genes:	283
Interacting mature miRNAs:	381
Transcripts:	ENSRNOT00000011237
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70212	Niddm25	Non-insulin dependent diabetes mellitus QTL 25	3.54		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	5	1	131345958	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
2290448	Scl54	Serum cholesterol level QTL 54	2.93		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	31663789	131345958	Rat
1641912	Alcrsp18	Alcohol response QTL 18			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	5	35189153	141643988	Rat
1549845	Scl44	Serum cholesterol level QTL 44	6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	40128307	148607290	Rat
1331801	Rf33	Renal function QTL 33	4.149		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	5	43726656	129132602	Rat
1578766	Tcas11	Tongue tumor susceptibility QTL 11	4.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	5	46711509	161317411	Rat
1576312	Emca8	Estrogen-induced mammary cancer QTL 8	4.1		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	50328551	141643988	Rat
70189	Mcs5	Mammary carcinoma susceptibility QTL 5	10.51		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	5	55805606	132207589	Rat
1358895	Bp254	Blood pressure QTL 254	3.6	0.0003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	58829236	128034027	Rat
61426	Scl2	Serum cholesterol level QTL 2	7.3	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	5	59793399	143070159	Rat
61393	Bp7	Blood pressure QTL 7	4.5	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	60293434	161481680	Rat
2306971	Anxrr21	Anxiety related response QTL 21	9.47		fear/anxiety-related behavior trait (VT:1000241)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	5	66174080	124160948	Rat
1354598	Srn6	Serum renin concentration QTL 6	3.8		blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	5	69540295	151018848	Rat
1298070	Scl18	Serum cholesterol level QTL 18	3.7		blood LDL cholesterol amount (VT:0000181)	calculated plasma low density lipoprotein cholesterol level (CMO:0001245)	5	79584860	124584860	Rat
1598846	Bp293	Blood pressure QTL 293	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	79584860	124584860	Rat
1598859	Cm66	Cardiac mass QTL 66	2		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	79584860	124584860	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1298086	Bp156	Blood pressure QTL 156			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	84132602	129132602	Rat
7411601	Foco12	Food consumption QTL 12	19.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	87468046	132468046	Rat
7411564	Bw135	Body weight QTL 135		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	87468046	132468046	Rat
7411582	Foco3	Food consumption QTL 3	7.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	5	87468046	132468046	Rat
6903316	Bw113	Body weight QTL 113	2	0.0103	body mass (VT:0001259)	body weight (CMO:0000012)	5	87765973	132765973	Rat
1358889	Bp261	Blood pressure QTL 261	2.86		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	5	90067849	128034027	Rat
1358909	Kidm25	Kidney mass QTL 25	1.87		kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	5	90067849	128034027	Rat
631527	Tls1	T-lymphoma susceptibility QTL 1	0	0.001	thymus integrity trait (VT:0010555)	post-insult time to onset of T-cell lymphoma (CMO:0001907)	5	90450144	135450144	Rat
61452	Ciaa5	CIA Autoantibody QTL 5	3.5		blood autoantibody amount (VT:0003725)	calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)	5	94858972	143070159	Rat
1331796	Thshl2	Thyroid stimulating hormone level QTL 2	2.3		blood thyroid-stimulating hormone amount (VT:0005119)	serum thyroid stimulating hormone level (CMO:0001248)	5	97059760	147465714	Rat
2317753	Glom24	Glomerulus QTL 24	3.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	5	97570330	136479578	Rat
1358187	Emca1	Estrogen-induced mammary cancer QTL 1	4.4		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	5	99216724	148607142	Rat
1578673	Bmd13	Bone mineral density QTL 13	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	5	103689353	148689353	Rat
2317056	Wbc3	White blood cell count QTL 3	2.51	0.01	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	5	105999803	150999803	Rat
7207488	Bss110	Bone structure and strength QTL 1	8.4		femur strength trait (VT:0010010)	femur stiffness (CMO:0001674)	5	106906205	151906205	Rat
7207491	Bss112	Bone structure and strength QTL 112	7		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	5	106906205	151906205	Rat
7207481	Bss106	Bone structure and strength QTL 106	7.9		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	5	106906205	151906205	Rat
7207486	Bss109	Bone structure and strength QTL 109			femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	5	106906205	151906205	Rat
1549838	Bss4	Bone structure and strength QTL 4	9.2		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	5	106906205	151906205	Rat
1298089	Scl14	Serum cholesterol level QTL 14	5.8	0.0004	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	108845856	153845856	Rat
1598847	Cm62	Cardiac mass QTL 62	3.4		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	108845856	153845856	Rat
8657050	Bw146	Body weight QTL 146	19.84	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	108938288	153938288	Rat
8694441	Bw169	Body weight QTL 169	17.61	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	5	111416838	156416838	Rat
8694198	Abfw3	Abdominal fat weight QTL 3	16.13	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	5	111416838	156416838	Rat
8694389	Bw160	Body weight QTL 160	6.17	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	5	111416838	156416838	Rat
8552960	Pigfal15	Plasma insulin-like growth factor 1 level QTL 15			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	111416838	156416838	Rat
7794739	Bp372	Blood pressure QTL 372		0.0058	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	117913688	125222967	Rat
1582230	Bw78	Body weight QTL 78	3.2	0.0016	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	5	119085612	128034027	Rat

Markers in Region

RH129678

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	120,001,921 - 120,002,132 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	124,765,215 - 124,765,425	NCBI	Rnor6.0
Rnor_5.0	5	128,625,854 - 128,626,064	UniSTS	Rnor5.0
RGSC_v3.4	5	126,196,815 - 126,197,025	UniSTS	RGSC3.4
Celera	5	118,551,689 - 118,551,899	UniSTS
Cytogenetic Map	5	q34	UniSTS

BF410958

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	119,936,995 - 119,937,085 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	124,700,124 - 124,700,213	NCBI	Rnor6.0
Rnor_5.0	5	128,561,106 - 128,561,195	UniSTS	Rnor5.0
RGSC_v3.4	5	126,131,326 - 126,131,415	UniSTS	RGSC3.4
Celera	5	118,487,012 - 118,487,101	UniSTS
Cytogenetic Map	5	q34	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	54	41	16	41	8	11	74	35	39	11	8
Low			3		3						2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_138905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC072544	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ222520	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000162	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Y07783	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000011237 ⟹ ENSRNOP00000011237

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	119,927,085 - 120,002,205 (+)	Ensembl
Rnor_6.0 Ensembl	5	124,690,214 - 124,765,498 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106902 ⟹ ENSRNOP00000095295

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	119,927,085 - 119,995,656 (+)	Ensembl

RefSeq Acc Id:

NM_138905 ⟹ NP_620260

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	5	119,927,085 - 120,002,206 (+)	NCBI
Rnor_6.0	5	124,690,214 - 124,765,499 (+)	NCBI
Rnor_5.0	5	128,551,196 - 128,626,138 (+)	NCBI
RGSC_v3.4	5	126,121,416 - 126,197,099 (+)	RGD
Celera	5	118,477,102 - 118,551,973 (+)	RGD

Sequence:

show sequence

CAGAAGGAGGAGGCAGAGTTGGAGTTGGGCAGACGCTGTGGAGAGCTAGCTGCAGGACGCTGCG
GAGTTGCAGGGCTCCGCGCTGCTCCATTCATTAAGTAGCTGCGGAGGATCGTGGCCGGACGCCG
ACGCTGCCCACTCGCAAACTTCAGCACGCAGACGCACGCCAGCCCGGCGCGTCCGGGACAGCAC
AGTTTTGCAAAAGTTCCTGCTCGGGATTTGGCTCTCTTCCCTTTGGACTAGCGAACAGTTTGGG
GTTGAGAGGAAAGCAGAGGCGCTCAGGGGGAAACCTACCCGCGTCTGCAGTTGGAGCTACTCGG
CCGGGCTGTACACTCGCCGCCGCGTCCCGAGCCCGCAGATCCGCTCCTGAGCAGCGGCGGCCCG
CAGCGCCCCGGGAGGCTCCCCGCAGCCAGCGCCATGCAAAGCTACAAGTACGACAAGGCGATCG
TCCCTGAGAGTAAGAACGGCGGTAGCCCGGCGCTCAACAACAACCCGAGGAAAGGCGGCAGCAA
GCGGGTGCTGCTCATCTGCCTCGACCTCTTCTGCCTCTTCATGGCGGCTCTGCCCTTCCTCATC
ATCGAGACAAGCACCATTAAGCCTTATCGTCGAGGGTTTTACTGCAACGACGAGAGCATCAAGT
ACCCCCTGAAAGTCAGCGAGACTATAAACGACGCCGTGCTCTGTGCGGTGGGGATCGTCATCGC
CATCCTGGCGATCATCACGGGGGAATTCTACCGGATCTATTACCTCAAGGAGAAGTCCCGATCC
ACCATTCAGAACCCTTATGTGGCCGCTCTCTATAAGCAAGTGGGATGCTTCCTTTTCGGCTGTG
CCATCAGCCAGTCCTTCACAGACATCGCCAAAGTGTCCATTGGGCGCCTGAGGCCTCACTTCCT
CAGCGTCTGTGACCCTGATTTCAGTCAGATCAATTGCTCCGAGGGCTACATTCAGAACTACAGG
TGCCGAGGAGAAGACAGCAAAGTACAGGAGGCCAGGAAATCCTTCTTCTCGGGCCACGCCTCCT
TCTCCATGTTCACAATGCTGTATCTGGTGCTTTATCTACAGGCCCGCTTCACCTGGCGTGGGGC
CCGGCTCCTCCGCCCCCTCCTGCAGTTCACTTTGCTCATGATGGCCTTCTACACGGGATTGTCA
CGTGTATCTGACTACAAACACCATCCTAGCGATGTCCTGGCAGGATTTGCCCAAGGAGCTCTGG
TGGCCTGCTGCATAGTGTTCTTCGTGTCTGACCTCTTCAAGACTAAGACGACCCTCTCACTGCC
TGCCCCCGCGATCAGGAGAGAGATCCTGTCTCCTGTAGACATCATGGACAGGAGCAATCACCAC
AACATGGTGTAGGTGCTGCGGCCTCCAGAGCACTTTCTCTGAAGCGACTGCTTGACAGCATGTC
CCTGCTGCTCTCCAATCTCATCAGACAGTAGAATGTAGGGAAAAGCTTTTTGCCCGATGGATTT
TGAAAACATTTAAAGAAAAAAAAAAAGCCTTACCTTGTGGCCTTCCAAAATAGGTTGTTTGCCT
GTGTGGAGACAACAGTGCCGGAGTCCTGAGTGCTGGCTGCACAGCTGGCTAAGTGTTCATGTTC
TAGTGAGCACGGGCTTGTCAGGAGCAAAACACTAGGATAATTGAGCAGAGGCTGTGGTCACCTT
TTGTGACCCGAGAAATCCCAGGCCAGAATAGCGGGGGCGCTTATGTAGCATGCAAGGCCTGAAC
CAGCACCGAATCAGCCCCTCTGCCTGCCCCACTCTACTGTGACTTTGATTCAAGGAAGTTTTTG
CGCTTTGAAATACCGGGAATGAACACACAGTTTTTCAGTCGAGGGATCAGATCCTGAATCCAAA
CCCCATGTCCTGAGGCCTCTGTCATCTCTCCATCCCCAGGCTAACAACCACAGTCCCCTCACTT
TTAGAGATTAGGAGACCCTTTGTGGAAGAGTGAACTTCACAAATAGCACAAGTTCAGAAGACAT
GTAGGGTGTCTTCTCACACACCACACTGTGACGCACGCGGAACTGCCATTGCGGGGTCAATCAC
CAGGCACTTGCACGTGTAGAAACCCGTAGACTTTGGTTACTGCTATATCCCCCTTGAGATCCTT
GCTGGGTGCCTACCAGGATTTCATGTGAGGGCCAGGGATGCATAGGCATGGCCAACCTTTGGTG
GATCAAAAGAGCCTCAGTAGAGAGACAGGGAGGGAGGGAGAGGGCAGAATGAAAAAAAAGTGAA
CCAATTCTTTTGGCTCCTTGGGTTTAGAGAGAGCCAGGGTAGCAGACAGTCTTATGCCCAAAAG
GTACCCTTCCAGATAAGGGAGCCCCAAGGGTCTTCGCAGGAGTTGATCTTGCTGTGTAAAGCAC
TGTTGTCGCAGGGTTGACCCCTGGGACAGTTCTTGGTGGGTTCTGCTGGGCAGAACACATAGGT
TAAATCTGTGTCGAGAGTTTTCCTCATACTCTATCCACAAGTGTCCTTCCAAGCAAGGTCCCAC
TCTAGCCAGTAGACAAGGTCCCTTCTACTGAACCTCCAAGGAAAAGAAGAAGGAGAAGAAAAAG
TGCTTTTCAAATCTTTCAAAGGGCTACATGTAACCATATGGATCAACCACATGCATATCCTCCC
AGACTCCGTCCTTTCATTTCAACATATAGCAAGCTATGATTTTATATATAAAATTATATAAATA
ATGTATAAAACAGTAAAAGTTAACTATGTAAGATATTATTTCTGAAACAATGTTAGTCACACCC
ACTATGATTATAAACTGTGTCTTGACCTGTGTTATTTACTTTAGCTGCTTAAAGGAGCATTGAG
TTTTTTTGGTTTGTTTTTTTTTTTTTTTTAATCTCAACTAAAGATATCATAGTTCTGTGGTAGC
CATTGTTTTACAATGAAATAACTGCGACTAGAGGGAAAAAGAACTGTATAAAAACATTAAATTG
TCAGTATTTTTGTAAGGTTCCGTTTTGTAAAGAGAATAATATTCAAACACTTCTGTGGCATACA
AAGTGAAAAATGTGTATCTGAGAAACTAAACATGTATTAAATGTGCTTTTTAAAATAAAAGCTC
ATAACATGAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_620260	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH72544	(Get FASTA)	NCBI Sequence Viewer
	CAA69106	(Get FASTA)	NCBI Sequence Viewer
	EDL97884	(Get FASTA)	NCBI Sequence Viewer
	EDL97885	(Get FASTA)	NCBI Sequence Viewer
	EDL97886	(Get FASTA)	NCBI Sequence Viewer
	P97544	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_620260 ⟸ NM_138905

- UniProtKB:

P97544 (UniProtKB/Swiss-Prot), Q6IMX4 (UniProtKB/TrEMBL), A6JRU2 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQSYKYDKAIVPESKNGGSPALNNNPRKGGSKRVLLICLDLFCLFMAALPFLIIETSTIKPYRR
GFYCNDESIKYPLKVSETINDAVLCAVGIVIAILAIITGEFYRIYYLKEKSRSTIQNPYVAALY
KQVGCFLFGCAISQSFTDIAKVSIGRLRPHFLSVCDPDFSQINCSEGYIQNYRCRGEDSKVQEA
RKSFFSGHASFSMFTMLYLVLYLQARFTWRGARLLRPLLQFTLLMMAFYTGLSRVSDYKHHPSD
VLAGFAQGALVACCIVFFVSDLFKTKTTLSLPAPAIRREILSPVDIMDRSNHHNMV

hide sequence

RefSeq Acc Id:

ENSRNOP00000011237 ⟸ ENSRNOT00000011237

RefSeq Acc Id:

ENSRNOP00000095295 ⟸ ENSRNOT00000106902

Protein Domains

Phosphatidic acid phosphatase type 2/haloperoxidase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P97544-F1-model_v2	AlphaFold	P97544	1-312	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620454	AgrOrtholog
BioCyc Gene	G2FUF-40477	BioCyc
Ensembl Genes	ENSRNOG00000008116	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000011237	ENTREZGENE
	ENSRNOP00000011237.3	UniProtKB/TrEMBL
	ENSRNOP00000095295.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000011237	ENTREZGENE
	ENSRNOT00000011237.6	UniProtKB/TrEMBL
	ENSRNOT00000106902.1	UniProtKB/TrEMBL
Gene3D-CATH	Phosphatidic acid phosphatase type 2/haloperoxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7105872	IMAGE-MGC_LOAD
InterPro	P_Acid_Pase_2/haloperoxi_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	P_Acid_Pase_2/haloperoxidase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PLPP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:192270	UniProtKB/TrEMBL
MGC_CLONE	MGC:91483	IMAGE-MGC_LOAD
NCBI Gene	192270	ENTREZGENE
PANTHER	PTHR10165	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10165:SF79	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	PAP2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Plpp3	PhenoGen
SMART	acidPPc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48317	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6AND8_RAT	UniProtKB/TrEMBL
	A6JRU2	ENTREZGENE, UniProtKB/TrEMBL
	F7FJE5_RAT	UniProtKB/TrEMBL
	P97544	ENTREZGENE, UniProtKB/Swiss-Prot
	Q6IMX4	ENTREZGENE
UniProt Secondary	Q6IMX4	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-10-26	Plpp3	phospholipid phosphatase 3	Ppap2b	phosphatidic acid phosphatase type 2B	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Ppap2b	phosphatidic acid phosphatase type 2B		ER transmembrane protein Dri 42	Name updated	1299863	APPROVED
2004-09-10	Ppap2b	ER transmembrane protein Dri 42	Dri42		Symbol and Name updated	1299863	APPROVED
2002-08-07	Dri42	ER transmembrane protein Dri 42			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_cellular_localization	resident in the endoplasmic reticulum	632577
gene_expression	expressed in intestine	632577
gene_regulation	increased during epithelial differentiation	632577

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - KEGG (archival)