Hspa5 (heat shock protein family A (Hsp70) member 5) - Rat Genome Database

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Gene: Hspa5 (heat shock protein family A (Hsp70) member 5) Rattus norvegicus
Symbol: Hspa5
Name: heat shock protein family A (Hsp70) member 5
RGD ID: 2843
Description: Enables misfolded protein binding activity and unfolded protein binding activity. Involved in several processes, including cellular response to cAMP; cellular response to gamma radiation; and luteolysis. Acts upstream of or within response to endoplasmic reticulum stress. Located in several cellular components, including dendritic shaft; neuronal cell body; and smooth endoplasmic reticulum. Biomarker of post-traumatic stress disorder; steatotic liver disease; transient cerebral ischemia; ureteral obstruction; and visual epilepsy. Human ortholog(s) of this gene implicated in dopamine beta-hydroxylase deficiency. Orthologous to human HSPA5 (heat shock protein family A (Hsp70) member 5); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; etoposide pharmacodynamics pathway; INTERACTS WITH (+)-pilocarpine; (+)-schisandrin B; (R)-adrenaline.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 78 kDa glucose-regulated protein; BIP; endoplasmic reticulum chaperone BiP; GRP 78; GRP-78; GRP78; heat shock 70 kDa protein 5; Heat shock 70kD protein 5; heat shock 70kDa protein 5 (glucose-regulated protein); heat shock protein 5; heat shock protein 70 family protein 5; heat shock protein family A member 5; HSP70 family protein 5; immunoglobulin heavy chain-binding protein; steroidogenesis-activator polypeptide
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
GRCr8338,453,016 - 38,457,475 (+)NCBIGRCr8
mRatBN7.2318,055,507 - 18,059,969 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl318,055,405 - 18,059,891 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx321,123,611 - 21,128,067 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0329,708,632 - 29,713,088 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0327,962,245 - 27,966,702 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0313,838,304 - 13,842,763 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl313,838,304 - 13,842,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0319,157,874 - 19,162,333 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4313,783,825 - 13,788,022 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1313,680,196 - 13,684,394 (+)NCBI
Celera312,776,654 - 12,781,113 (+)NCBICelera
RH 3.4 Map3151.7RGD
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)