GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Hspa5 | increases expression | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | Cadmium results in increased expression of HSPA5 mRNA; Cadmium results in increased expression of HSPA5 protein | PMID:16020198 PMID:20600546 PMID:21694771 | Hspa5 | multiple interactions | ISO | Hspa5 (Mus musculus) | 6480464 | CTD | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSPA5 protein | PMID:37261864 | Hspa5 | multiple interactions | ISO | HSPA5 (Homo sapiens) | 6480464 | CTD | [Cadmium Chloride co-treated with Cadmium] results in increased expression of HSPA5 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSPA5 protein; [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of HSPA5 protein; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSPA5 protein] | PMID:33040242 PMID:34516972 PMID:34687772 PMID:37300854 | |
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