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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hspa5
Name: heat shock protein family A (Hsp70) member 5
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa5increases expressionISOHSPA5 (Homo sapiens)6480464CTDCapsaicin results in increased expression of HSPA5; Capsaicin results in increased expression of HSPA5 proteinPMID:19139269 PMID:19699254 PMID:21859781
Hspa5increases localizationISOHSPA5 (Homo sapiens)6480464CTDCapsaicin results in increased localization of HSPA5 proteinPMID:19331147
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