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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2843
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hspa5
Name: heat shock protein family A (Hsp70) member 5
Acc ID: CHEBI:16587
Term: 20-hydroxyecdysone
Definition: An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.
Chemical ID: MESH:D004441
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspa5decreases expressionISORGD:7364476480464CTDEcdysterone results in decreased expression of HSPA5 protein

PMID:29126784
Hspa5increases expressionISORGD:7364476480464CTDEcdysterone results in increased expression of HSPA5 mRNA

PMID:29126784
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.