Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2843
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Hspa5
Name:	heat shock protein family A (Hsp70) member 5

Acc ID:	CHEBI:16587
Term:	20-hydroxyecdysone
Definition:	An ecdysteroid that is ecdysone substituted by a hydroxy group at position 20.
Chemical ID:	MESH:D004441

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Hspa5	decreases expression	ISO	RGD:736447	6480464	CTD	Ecdysterone results in decreased expression of HSPA5 protein	PMID:29126784
Hspa5	increases expression	ISO	RGD:736447	6480464	CTD	Ecdysterone results in increased expression of HSPA5 mRNA	PMID:29126784

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