Slc40a1 (solute carrier family 40 member 1)

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Gene: Slc40a1 (solute carrier family 40 member 1) Rattus norvegicus

Analyze

Symbol:

Slc40a1 (Ensembl: NEWGENE_620180)

Name:

solute carrier family 40 member 1

RGD ID:

620180

Description:

Predicted to enable ferrous iron transmembrane transporter activity; identical protein binding activity; and peptide hormone binding activity. Predicted to be involved in cellular iron ion homeostasis and iron ion export across plasma membrane. Predicted to act upstream of or within several processes, including multicellular organismal iron ion homeostasis; regulation of transcription by RNA polymerase II; and spleen trabecula formation. Predicted to be located in several cellular components, including cytosol; nucleoplasm; and synaptic vesicle. Predicted to be active in basolateral plasma membrane. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1); PARTICIPATES IN iron efflux pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CAR1; cell adhesion regulator; ferroportin 1; ferroportin-1; Fpn1; NEWGENE_620180; Slc11a3; Slc39a1; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	48,033,526 - 48,053,876 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	48,033,526 - 48,051,481 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	56,559,843 - 56,577,824 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	61,682,660 - 61,700,640 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	59,978,656 - 59,996,636 (-)	NCBI	Rnor_WKY
Rnor_6.0	9	52,819,451 - 52,830,461 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	52,894,365 - 52,912,293 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	52,560,116 - 52,579,079 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	44,977,430 - 44,995,358 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	44,979,984 - 44,996,778 (-)	NCBI
Celera	9	45,700,875 - 45,718,803 (-)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aceruloplasminemia (ISO)

anemia (ISO)

autistic disorder (ISO)

Ehlers-Danlos syndrome classic type 1 (ISO)

Ehlers-Danlos Syndrome Type 4 (ISO)

endometriosis (ISO)

hemochromatosis (ISO)

hemochromatosis type 1 (ISO)

hemochromatosis type 4 (ISO)

Hemolysis (ISO)

Iron Overload (ISO)

Liver Neoplasms (ISO)

Neoplastic Cell Transformation (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-acetamidofluorene (EXP)

2-tert-butylhydroquinone (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP,ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,4-dihydroxybenzoate (ISO)

3,4-methylenedioxymethamphetamine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3H-1,2-dithiole-3-thione (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

4-tert-Octylphenol (EXP)

5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole (ISO)

acetamide (EXP)

acrylamide (EXP)

actinomycin D (ISO)

aflatoxin B1 (EXP,ISO)

alcohol (ISO)

all-trans-retinoic acid (EXP,ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

apocynin (ISO)

Aroclor 1254 (EXP)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

busulfan (ISO)

buta-1,3-diene (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chloroprene (ISO)

chlorpyrifos (ISO)

chromium(6+) (EXP,ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

cobalt atom (ISO)

cobalt dichloride (EXP,ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

copper(II) sulfate (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

cytarabine (ISO)

desferrioxamine B (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diethyl maleate (ISO)

diethylstilbestrol (EXP)

diquat (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

epoxiconazole (ISO)

erastin (EXP,ISO)

ethanol (ISO)

ferric ammonium citrate (EXP,ISO)

ferrostatin-1 (ISO)

flutamide (EXP)

folic acid (ISO)

gadolinium trichloride (EXP)

Gastrodin (ISO)

gentamycin (EXP)

glycidol (EXP)

hexane (ISO)

hypochlorous acid (ISO)

indometacin (ISO)

iron atom (EXP,ISO)

iron dextran (ISO)

iron(0) (EXP,ISO)

iron(2+) sulfate (anhydrous) (ISO)

iron(III) nitrilotriacetate (ISO)

isoprenaline (ISO)

L-glutamic acid (ISO)

lamivudine (ISO)

lead diacetate (EXP,ISO)

lipopolysaccharide (ISO)

maneb (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (EXP)

mercury dibromide (ISO)

mercury dichloride (EXP)

methamphetamine (EXP)

methapyrilene (ISO)

methimazole (EXP)

methylmercury chloride (ISO)

mithramycin (EXP)

N-acetyl-L-cysteine (ISO)

N-nitrosodiethylamine (EXP,ISO)

naphthalene (EXP)

nefazodone (EXP)

nickel atom (ISO)

nickel dichloride (EXP)

nickel sulfate (ISO)

nitric oxide (EXP)

nitrofen (EXP)

omeprazole (ISO)

oxidopamine (EXP,ISO)

p-chloromercuribenzoic acid (ISO)

p-tert-Amylphenol (EXP)

panobinostat (ISO)

paracetamol (EXP,ISO)

paraquat (ISO)

pentachlorophenol (ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (EXP)

permethrin (EXP)

phenacetin (EXP)

phenobarbital (ISO)

phenylhydrazine (EXP)

phenylmercury acetate (ISO)

phorone (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

progesterone (ISO)

quercetin (EXP,ISO)

reactive oxygen species (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

SCH 23390 (EXP)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

succimer (ISO)

sulforaphane (ISO)

tamoxifen (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

toluene (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

trimellitic anhydride (ISO)

triptonide (ISO)

tunicamycin (ISO)

valproic acid (ISO)

zidovudine (ISO)

zinc atom (EXP,ISO)

zinc(0) (EXP,ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA,ISO)

cellular iron ion homeostasis (IEA,ISO)

endothelium development (IEA,ISO)

establishment of localization in cell (IEA,ISO)

iron ion export across plasma membrane (IEA,ISO)

iron ion homeostasis (IBA,ISO)

iron ion transmembrane transport (IBA,IEA,ISO)

iron ion transport (ISO,NAS)

lymphocyte homeostasis (IEA,ISO)

multicellular organismal iron ion homeostasis (IEA,ISO)

negative regulation of apoptotic process (IEA,ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of transcription from RNA polymerase II promoter in response to iron (IEA,ISO)

spleen development (ISO)

spleen trabecula formation (IEA,ISO)

transcription by RNA polymerase II (IEA,ISO)

Cellular Component

basolateral plasma membrane (IBA,IEA,ISO)

cytosol (IEA,ISO)

membrane (IEA)

nucleoplasm (IEA,ISO)

plasma membrane (ISO)

synaptic vesicle (IEA,ISO)

Molecular Function

ferrous iron transmembrane transporter activity (IEA,ISO)

identical protein binding (IEA,ISO)

iron ion transmembrane transporter activity (IBA,IEA,ISO,NAS)

metal ion binding (IEA)

peptide hormone binding (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

iron efflux pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Interleukin-1beta up-regulates iron efflux in rat C6 glioma cells through modulation of ceruloplasmin and ferroportin-1 synthesis.	di Patti MC, etal., Neurosci Lett 2004 Jun 10;363(2):182-6.
2.	Ironing out Ferroportin.	Drakesmith H, etal., Cell Metab. 2015 Nov 3;22(5):777-87. doi: 10.1016/j.cmet.2015.09.006. Epub 2015 Oct 1.
3.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4.	Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.	Itoh A, etal., Brain Res Mol Brain Res 1998 Nov 20;62(2):175-86.
5.	Distribution of ferroportin1 protein in different regions of developing rat brain.	Jiang DH, etal., Dev Neurosci 2002;24(2-3):94-8.
6.	DMT1 and FPN1 expression during infancy: developmental regulation of iron absorption.	Leong WI, etal., Am J Physiol Gastrointest Liver Physiol 2003 Dec;285(6):G1153-61. Epub 2003 Sep 04.
7.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Novel mutation in ferroportin1 is associated with autosomal dominant hemochromatosis.	Wallace DF, etal., Blood 2002 Jul 15;100(2):692-4.
14.	Hepcidin regulation of ferroportin 1 expression in the liver and intestine of the rat.	Yeh KY, etal., Am J Physiol Gastrointest Liver Physiol 2004 Mar;286(3):G385-94. Epub 2003 Oct 30.

Additional References at PubMed

PMID:8889548	PMID:10477520	PMID:10828623	PMID:12091367	PMID:12431995	PMID:14972659	PMID:15084469	PMID:15114483	PMID:15342464	PMID:15514116	PMID:15888661	PMID:15944915
PMID:16081696	PMID:17383861	PMID:17561842	PMID:18189270	PMID:18839536	PMID:18974313	PMID:19234114	PMID:19252488	PMID:19596281	PMID:19766498	PMID:19913091	PMID:20007457
PMID:20019163	PMID:20530874	PMID:20564203	PMID:21473866	PMID:21570398	PMID:21700773	PMID:21785164	PMID:22469696	PMID:22659129	PMID:22682227	PMID:23395172	PMID:23506423
PMID:24174620	PMID:25115800	PMID:25318588	PMID:25745840	PMID:26617777	PMID:26788496	PMID:28273797	PMID:29757912	PMID:30027341	PMID:34748769

Genomics

Comparative Map Data

Slc40a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	9	48,033,526 - 48,053,876 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	9	48,033,526 - 48,051,481 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	9	56,559,843 - 56,577,824 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	9	61,682,660 - 61,700,640 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	9	59,978,656 - 59,996,636 (-)	NCBI	Rnor_WKY
Rnor_6.0	9	52,819,451 - 52,830,461 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	52,894,365 - 52,912,293 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	9	52,560,116 - 52,579,079 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	44,977,430 - 44,995,358 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	9	44,979,984 - 44,996,778 (-)	NCBI
Celera	9	45,700,875 - 45,718,803 (-)	NCBI		Celera
Cytogenetic Map	9	q22	NCBI

SLC40A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	189,560,590 - 189,580,786 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	2	189,560,590 - 189,583,758 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	190,425,316 - 190,445,512 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	190,133,561 - 190,153,858 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	190,250,823 - 190,271,119	NCBI
Celera	2	184,020,234 - 184,040,455 (-)	NCBI		Celera
Cytogenetic Map	2	q32.2	NCBI
HuRef	2	182,284,805 - 182,305,032 (-)	NCBI		HuRef
CHM1_1	2	190,431,102 - 190,451,326 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	190,049,828 - 190,070,025 (-)	NCBI		T2T-CHM13v2.0

Slc40a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	45,947,230 - 45,965,690 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	45,947,228 - 45,965,683 (-)	Ensembl		GRCm39 Ensembl
GRCm38	1	45,908,070 - 45,926,532 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	45,908,068 - 45,926,523 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	45,964,915 - 45,982,439 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	45,852,630 - 45,870,079 (-)	NCBI		MGSCv36	mm8
Celera	1	46,240,344 - 46,257,933 (-)	NCBI		Celera
Cytogenetic Map	1	C1.1	NCBI

Slc40a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	9,253,734 - 9,271,916 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	9,253,734 - 9,271,732 (+)	NCBI	ChiLan1.0	ChiLan1.0

SLC40A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	2B	194,787,575 - 194,808,129 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2B	194,787,575 - 194,810,993 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	2B	76,867,908 - 76,888,403 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SLC40A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	37	308,054 - 329,037 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	37	303,104 - 368,865 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	37	1,278,631 - 1,299,609 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	37	196,731 - 217,705 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	37	183,743 - 312,839 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	37	209,278 - 230,249 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	37	177,455 - 198,429 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	37	205,666 - 226,640 (-)	NCBI		UU_Cfam_GSD_1.0

Slc40a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405303	148,421,846 - 148,441,474 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936506	8,396,912 - 8,416,374 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936506	8,396,593 - 8,415,069 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC40A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	15	94,141,988 - 94,167,408 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	15	94,140,635 - 94,161,793 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	15	105,177,377 - 105,198,528 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC40A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	10	75,076,286 - 75,097,742 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	10	75,075,971 - 75,096,271 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666040	124,382,259 - 124,402,681 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc40a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624899	685,097 - 702,440 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624899	685,166 - 701,725 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slc40a1
130 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	464
Count of miRNA genes:	237
Interacting mature miRNAs:	285
Transcripts:	ENSRNOT00000005228, ENSRNOT00000073557
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10054125	Srcrt7	Stress Responsive Cort QTL 7	3.33	0.0011	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	9	1	87073594	Rat
1331757	Cdexp1	CD45RC expression in CD8 T cells QTL 1	4.3		CD8-positive T cell quantity (VT:0008077)	blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)	9	1024537	67509080	Rat
631211	Bw4	Body weight QTL4	5.31		retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	9	5109826	50109826	Rat
11353947	Bp392	Blood pressure QTL 392			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	7283252	52283252	Rat
9589133	Insul26	Insulin level QTL 26	17.96	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	9	8952560	53952560	Rat
7411609	Foco16	Food consumption QTL 16	25.6	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	8952560	53952560	Rat
631680	Cm11	Cardiac mass QTL 11	3.1	0.00089	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	9	20430519	65430519	Rat
70186	Niddm26	Non-insulin dependent diabetes mellitus QTL 26	3.87		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	9	22071169	86369743	Rat
631643	Bp120	Blood pressure QTL 120	3	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	22071200	67071200	Rat
1598823	Memor16	Memory QTL 16	1.9		exploratory behavior trait (VT:0010471)	difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)	9	22133322	49968732	Rat
7207805	Bmd88	Bone mineral density QTL 88	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	9	23754024	58157242	Rat
1300180	Bw14	Body weight QTL 14	3.776		body mass (VT:0001259)	body weight (CMO:0000012)	9	23754024	61381613	Rat
7207814	Bmd91	Bone mineral density QTL 91	3.5		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	9	23754144	83851531	Rat
70218	Cm28	Cardiac mass QTL 28	8.3	0.0001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	9	25268044	79271759	Rat
724544	Uae9	Urinary albumin excretion QTL 9	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	9	25268044	114175309	Rat
731164	Uae25	Urinary albumin excretion QTL 25	3.5	0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	9	25661188	100929786	Rat
1641894	Alcrsp12	Alcohol response QTL 12			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	9	27468639	72468639	Rat
7411656	Foco26	Food consumption QTL 26	9.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	9	32535505	77535505	Rat
7411571	Bw138	Body weight QTL 138	14.3	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	9	32535505	77535505	Rat
1598834	Memor11	Memory QTL 11	2.5		exploratory behavior trait (VT:0010471)	average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)	9	36962359	77814038	Rat
8662828	Vetf6	Vascular elastic tissue fragility QTL 6	3.9		artery integrity trait (VT:0010639)	patent ductus arteriosus score (CMO:0002566)	9	36962359	92058970	Rat
2290450	Scl57	Serum cholesterol level QTL 57	4.15		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	9	36962359	95410867	Rat
6903941	Pur31	Proteinuria QTL 31		0.036	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	9	40194188	85194188	Rat
11353949	Bp393	Blood pressure QTL 393			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	40194188	85194188	Rat
61352	Bp34	Blood pressure QTL 34	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	42495343	79271511	Rat
10058949	Gmadr5	Adrenal mass QTL 5	2	0.014	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	9	42791513	87976209	Rat
11353951	Bp394	Blood pressure QTL 394			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	44649921	89649921	Rat
12879506	Pur33	Proteinuria QTL 33			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	9	44649921	89649921	Rat
11353957	Bmd92	Bone mineral density QTL 92		0.01	tibia mineral mass (VT:1000283)	volumetric bone mineral density (CMO:0001553)	9	46114199	91114199	Rat
6903937	Bp356	Blood pressure QTL 356		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	9	47902208	52283252	Rat

Markers in Region

D9Rat60

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	48,035,934 - 48,036,057 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	52,896,774 - 52,896,896	NCBI	Rnor6.0
Rnor_6.0	9	52,821,860 - 52,821,982	NCBI	Rnor6.0
Rnor_5.0	9	52,562,590 - 52,562,712	UniSTS	Rnor5.0
Rnor_5.0	9	52,487,676 - 52,487,798	UniSTS	Rnor5.0
RGSC_v3.4	9	44,979,838 - 44,979,961	RGD	RGSC3.4
RGSC_v3.4	9	44,979,839 - 44,979,961	UniSTS	RGSC3.4
RGSC_v3.1	9	44,981,242 - 44,981,612	RGD
Celera	9	45,703,284 - 45,703,406	UniSTS
SHRSP x BN Map	9	41.0698	UniSTS
SHRSP x BN Map	9	41.0698	RGD
FHH x ACI Map	9	32.43	RGD
Cytogenetic Map	9	q22	UniSTS

RH129386

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	48,033,867 - 48,034,064 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	52,894,707 - 52,894,903	NCBI	Rnor6.0
Rnor_6.0	9	52,819,793 - 52,819,989	NCBI	Rnor6.0
Rnor_5.0	9	52,485,609 - 52,485,805	UniSTS	Rnor5.0
Rnor_5.0	9	52,560,523 - 52,560,719	UniSTS	Rnor5.0
RGSC_v3.4	9	44,977,772 - 44,977,968	UniSTS	RGSC3.4
Celera	9	45,701,217 - 45,701,413	UniSTS
Cytogenetic Map	9	q22	UniSTS

RH136898

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	9	48,034,706 - 48,034,886 (+)	MAPPER	mRatBN7.2
Rnor_6.0	9	52,820,632 - 52,820,811	NCBI	Rnor6.0
Rnor_6.0	9	52,895,546 - 52,895,725	NCBI	Rnor6.0
Rnor_5.0	9	52,486,448 - 52,486,627	UniSTS	Rnor5.0
Rnor_5.0	9	52,561,362 - 52,561,541	UniSTS	Rnor5.0
RGSC_v3.4	9	44,978,611 - 44,978,790	UniSTS	RGSC3.4
Celera	9	45,702,056 - 45,702,235	UniSTS
Cytogenetic Map	9	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1	2	37	37	11	37				34	21	1
Low	2	41	20	4	8	4	8	11	74	1	20	10	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039082988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AF394785	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BI288312	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB808602	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473965	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CK364414	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV104407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CV796629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DY313693	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U76714	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000005228 ⟹ ENSRNOP00000005228

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	48,033,527 - 48,051,481 (-)	Ensembl
Rnor_6.0 Ensembl	9	52,894,365 - 52,912,293 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095235 ⟹ ENSRNOP00000086572

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	9	48,033,526 - 48,049,019 (-)	Ensembl

RefSeq Acc Id:

NM_133315 ⟹ NP_579849

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	48,033,526 - 48,051,455 (-)	NCBI
Rnor_6.0	9	52,819,451 - 52,830,461 (-)	NCBI
Rnor_5.0	9	52,560,116 - 52,579,079 (-)	NCBI
RGSC_v3.4	9	44,977,430 - 44,995,358 (-)	RGD
Celera	9	45,700,875 - 45,718,803 (-)	RGD

Sequence:

show sequence

CAGGCTTAGGGTCTACTGCGGCCGGTGGACCCTCCAACCCGCTTCCATAAGGCTTTAGCTTTCC
AACTTCAGCTACAGTGTTAGCTAAGTTTGGAAAGAAGACATAAAGAAGACCCCGGTGGCAGCTT
TGCTGTTCTTTGCCTTAGTTGTCCTTTGGGGTCTTTCGGCACAAGGCTGCTGTGCTTATAGCCG
TGCTATCTCCGGTTCCTCACACTCCTGTGAAGAAGCCCCTGGGCAAGAGCAGCTAAAGCTACTA
GCATCCGAACAAACAAGGGGAGAGCGTCTGGTGCCATGACCAAGTCAAGAGATCAGACCCATCA
GGAAGGATGCTGTGGATCTTTAGCAAACTACCTGACCTCAGCAAAATTCCTCCTCTACCTTGGC
CACTCTCTCTCCACTTGGGGGGATCGGATGTGGCACTTTGCAGTGTCTGTGTTTCTGGTGGAAC
TCTACGGAAACAGCCTCCTCTTGACAGCTGTCTACGGGTTGGTGGTGGCAGGCTCTGTTCTGGT
CCTGGGAGCCATCATTGGTGACTGGGTGGATAAGAATGCCAGACTTAAAGTGGCCCAGACGTCC
CTGGTGGTTCAGAATGTATCAGTCATTCTCTGCGGGATCATCCTGATGATGGTTTTCTTACACA
AGAATGAGCTTCTGAACATGTATCATGGATGGGTCCTTACTGTCTGCTACATCCTGATCATCAC
CATTGCAAACATTGCGAATTTGGCCAGTACTGCCACTGCAATTACAATCCAAAGGGACTGGATT
GTTGTCGTAGCAGGAGAAAACAGGAGCAGATTAGCAGACATGAATGCTACCATTAGAAGGATTG
ACCAGCTAACCAACATCCTGGCCCCCATGGCTGTTGGCCAGATTATGACATTCGGTTCCCCAGT
CATTGGCTGTGGTTTCATTTCTGGTTGGAATTTGGTGTCCATGTGTGTGGAGTACTTCTTGCTC
TGGAAGGTTTACCAGAAGACCCCTGCTCTGGCTGTAAAAGCTGCTCTCAAGGTAGAGGAGTCAG
AACTGAAGCAGCTGACCTCACCTAAAGATACTGAGCCAAAACCTTTGGAGGGAACTCACCTAAT
GGGTGAGAAAGACTCTAACATCCGTGAACTTGAATGTGAACAAGAACCCACCTGTGCCTCCCAG
ATCGCAGAACCCTTCCGCACTTTTCGAGATGGATGGGTCTCCTACTATAACCAGCCCGTATTTT
TGGCTGGCATGGGCCTGGCTTTCCTCTATATGACAGTCCTGGGCTTCGACTGTATCACCACAGG
ATATGCTTACACTCAGGGACTGAGTGGTTCCATCCTCAGTGTTTTGATGGGAGCATCAGCAATA
ACTGGAATAATGGGAACTGTGGCCTTCACTTGGCTACGTCGAAAATGTGGCCTTGTTCGGACTG
GTCTGTTCTCAGGACTGGCTCAGCTTTCTTGTTTGATCTTGTGTGTGATCTCCGTGTTCATGCC
TGGAAGCCCCTTGGACCTGTCTGTTTCTCCATTTGAAGATATCCGTTCTAGGTTTATACATGAG
GAGGCAGTGTCCTCAACTACCAAAATACCTGAAACAGAAATGCTTATGTCTAATGTGTCTAATG
TTGTCAATACCGTCCATGAGATGAGTACTAAATCCGTCCCCATAATCTCCGTCAGCCTGCTGTT
TGCAGGAGTCATTGCTGCTAGAATCGGTCTTTGGTCCTTTGATTTGACTGTGACACAGTTGCTG
CAAGAAAATGTAATTGAATCAGAAAGAGGCATTATCAATGGTGTGCAGAACTCCATGAACTACC
TTCTCGACCTTCTGCATTTCATCATGGTCATCTTGGCCCCAAATCCTGAAGCTTTTGGCTTGCT
AGTATTGATTTCAGTCTCCTTTGTGGCAATGGGACATCTTATGTATTTCCGTTTTGCCCAGAAG
ACTCTGGGCAACCAGATTTTTGTTTGTGCTCCTGATGAAAAGGAAGTTACAGATGAAAGTCAGC
CTAATACATCTGTTGTGTAAAATAGTTTAGCTGTGGCCCCTGTTACTAGATTTGTGGAGAGCAT
GTGTGCTTATTTTGTACTACAGAATTCCAATAAATGCCTGCACTTTTCTCTGTTTTTACTACAG
CTGTGCCTTAAGGGTTAGGGGCACTAACGAACCTTCACCAGCGAAGATGGTTATTTCTCCTTAC
ATGTAAACATGGGGAAATAAGAGGGAGAGGAAAAGTCAGCATGTGGGTAGGATGGGTTTAATGG
TAAAATGAGTTTCCCATACTCTTATGAGTATATTAAATTTTAAAGAGTGGCTGTCAGGTGAGTT
AAATTACTCCATAGTAGATATTGTCCACTAGAATGCAGATAAATCAATTCACCCCAAAACTCAC
TCTTGTAAAAGTCTGGCTCACTTCCCTTTTTTTTTTAAAGATGAGTAGTATTTTTCTCAGTTAC
GTTACAGAAACAAGTTTTTCTCCTTGTAGGAAGATTATAGTCTGATAATGAGCATTATTCTTAT
TAATCCCATTGAACTTAGGGAATTTATTATATGTGAAGGATGAAATACATAACTAAACTTCTTC
AAAAGGCTCATGGTATAACCTTTGCATTTTGACTATCAGCTAGGGCAAAATATTACAGTAATGT
GTGTATGTGGCTCTTCCTAAAATGACTGCAGAGAGAAGAAAAGCTGTAGATTTCTAGTGCAGTA
CAGAAGGACTTAAAGCACGTTATTGGTGTGGTTGTAGAAACTGGAAGCTAATGGGGAGGACCTC
ACGTAACCAGAGTCACTGTTGTCAGTGATCACTAACTATCCTGGTATATGAAAGAGCTGGCCCT
AGGCCTAGCACCTGACAGGCAGAAAAGCAGCCCACGCTTGGAAAGGACTGCACATCAATGATGA
GCTTGTACAGAGCATTTTACCTTCACTGACTTGGGCCGACGTGTTTATTATCTCTGTCTTTTTC
TAGAGCAAGAATAGTCACAAAGGTTCCCCTTTCAATATCTCTGAAAAGAATAAAGAAAAAACTG
TTTGTAAATATTTTTTAAACTGTTCTACAAGTCTTTTTGTAATATGCAGTACCAACATGGGACA
TTGCTTTAACTTTTGATGCACTTTCATGGAGACCGCCATGCGTTGCTAGGAGCACTTTCTTTCC
ATTTAATATTTTTCTTCACCCTTCTGCAGTATGACATAATGATTGACTATGTTATAAAATCTTC
ATAAAATATTTCTATATAAAATGTTTGTAAAATCTTAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017596804 ⟹ XP_017452293

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	48,033,541 - 48,052,438 (-)	NCBI

Sequence:

show sequence

TGTTCATTACCAGGTGTCATTCTGGCAGTGCTTCAAGCGTGCAAGTTGGTTGGAGTTTCAATGT
TGAGGATCACTCTTGAGGTGTTGACAGAACTGACAAAGTTGTCCTTTGGGGTCTTTCGGCACAA
GGCTGCTGTGCTTATAGCCGTGCTATCTCCGGTTCCTCACACTCCTGTGAAGAAGCCCCTGGGC
AAGAGCAGCTAAAGCTACTAGCATCCGAACAAACAAGGGGAGAGCGTCTGGTGCCATGACCAAG
TCAAGAGATCAGACCCATCAGGAAGGATGCTGTGGATCTTTAGCAAACTACCTGACCTCAGCAA
AATTCCTCCTCTACCTTGGCCACTCTCTCTCCACTTGGGGGGATCGGATGTGGCACTTTGCAGT
GTCTGTGTTTCTGGTGGAACTCTACGGAAACAGCCTCCTCTTGACAGCTGTCTACGGGTTGGTG
GTGGCAGGCTCTGTTCTGGTCCTGGGAGCCATCATTGGTGACTGGGTGGATAAGAATGCCAGAC
TTAAAGTGGCCCAGACGTCCCTGGTGGTTCAGAATGTATCAGTCATTCTCTGCGGGATCATCCT
GATGATGGTTTTCTTACACAAGAATGAGCTTCTGAACATGTATCATGGATGGGTCCTTACTGTC
TGCTACATCCTGATCATCACCATTGCAAACATTGCGAATTTGGCCAGTACTGCCACTGCAATTA
CAATCCAAAGGGACTGGATTGTTGTCGTAGCAGGAGAAAACAGGAGCAGATTAGCAGACATGAA
TGCTACCATTAGAAGGATTGACCAGCTAACCAACATCCTGGCCCCCATGGCTGTTGGCCAGATT
ATGACATTCGGTTCCCCAGTCATTGGCTGTGGTTTCATTTCTGGTTGGAATTTGGTGTCCATGT
GTGTGGAGTACTTCTTGCTCTGGAAGGTTTACCAGAAGACCCCTGCTCTGGCTGTAAAAGCTGC
TCTCAAGGTAGAGGAGTCAGAACTGAAGCAGCTGACCTCACCTAAAGATACTGAGCCAAAACCT
TTGGAGGGAACTCACCTAATGGGTGAGAAAGACTCTAACATCCGTGAACTTGAATGTGAACAAG
AACCCACCTGTGCCTCCCAGATCGCAGAACCCTTCCGCACTTTTCGAGATGGATGGGTCTCCTA
CTATAACCAGCCCGTATTTTTGGCTGGCATGGGCCTGGCTTTCCTCTATATGACAGTCCTGGGC
TTCGACTGTATCACCACAGGATATGCTTACACTCAGGGACTGAGTGGTTCCATCCTCAGTGTTT
TGATGGGAGCATCAGCAATAACTGGAATAATGGGAACTGTGGCCTTCACTTGGCTACGTCGAAA
ATGTGGCCTTGTTCGGACTGGTCTGTTCTCAGGACTGGCTCAGCTTTCTTGTTTGATCTTGTGT
GTGATCTCCGTGTTCATGCCTGGAAGCCCCTTGGACCTGTCTGTTTCTCCATTTGAAGATATCC
GTTCTAGGTTTATACATGAGGAGGCAGTGTCCTCAACTACCAAAATACCTGAAACAGAAATGCT
TATGTCTAATGTGTCTAATGTTGTCAATACCGTCCATGAGATGAGTACTAAATCCGTCCCCATA
ATCTCCGTCAGCCTGCTGTTTGCAGGAGTCATTGCTGCTAGAATCGGTCTTTGGTCCTTTGATT
TGACTGTGACACAGTTGCTGCAAGAAAATGTAATTGAATCAGAAAGAGGCATTATCAATGGTGT
GCAGAACTCCATGAACTACCTTCTCGACCTTCTGCATTTCATCATGGTCATCTTGGCCCCAAAT
CCTGAAGCTTTTGGCTTGCTAGTATTGATTTCAGTCTCCTTTGTGGCAATGGGACATCTTATGT
ATTTCCGTTTTGCCCAGAAGACTCTGGGCAACCAGATTTTTGTTTGTGCTCCTGATGAAAAGGA
AGTTACAGATGAAAGTCAGCCTAATACATCTGTTGTGTAAAATAGTTTAGCTGTGGCCCCTGTT
ACTAGATTTGTGGAGAGCATGTGTGCTTATTTTGTACTACAGAATTCCAATAAATGCCTGCACT
TTTCTCTGTTTTTACTACAGCTGTGCCTTAAGGGTTAGGGGCACTAACGAACCTTCACCAGCGA
AGATGGTTATTTCTCCTTACATGTAAACATGGGGAAATAAGAGGGAGAGGAAAAGTCAGCATGT
GGGTAGGATGGGTTTAATGGTAAAATGAGTTTCCCATACTCTTATGAGTATATTAAATTTTAAA
GAGTGGCTGTCAGGTGAGTTAAATTACTCCATAGTAGATATTGTCCACTAGAATGCAGATAAAT
CAATTCACCCCAAAACTCACTCTTGTAAAAGTCTGGCTCACTTCCCTTTTTTTTTTAAAGATGA
GTAGTATTTTTCTCAGTTACGTTACAGAAACAAGTTTTTCTCCTTGTAGGAAGATTATAGTCTG
ATAATGAGCATTATTCTTATTAATCCCATTGAACTTAGGGAATTTATTATATGTGAAGGATGAA
ATACATAACTAAACTTCTTCAAAAGGCTCATGGTATAACCTTTGCATTTTGACTATCAGCTAGG
GCAAAATATTACAGTAATGTGTGTATGTGGCTCTTCCTAAAATGACTGCAGAGAGAAGAAAAGC
TGTAGATTTCTAGTGCAGTACAGAAGGACTTAAAGCACGTTATTGGTGTGGTTGTAGAAACTGG
AAGCTAATGGGGAGGACCTCACGTAACCAGAGTCACTGTTGTCAGTGATCACTAACTATCCTGG
TATATGAAAGAGCTGGCCCTAGGCCTAGCACCTGACAGGCAGAAAAGCAGCCCACGCTTGGAAA
GGACTGCACATCAATGATGAGCTTGTACAGAGCATTTTACCTTCACTGACTTGGGCCGACGTGT
TTATTATCTCTGTCTTTTTCTAGAGCAAGAATAGTCACAAAGGTTCCCCTTTCAATATCTCTGA
AAAGAATAAAGAAAAAACTGTTTGTAAATATTTTTTAAACTGTTCTACAAGTCTTTTTGTAATA
TGCAGTACCAACATGGGACATTGCTTTAACTTTTGATGCACTTTCATGGAGACCGCCATGCGTT
GCTAGGAGCACTTTCTTTCCATTTAATATTTTTCTTCACCCTTCTGCAGTATGACATAATGATT
GACTATGTTATAAAATCTTCATAAAATATTTCTATATAAAATGTTTGTAAAATCTTCATTTTCC
TTTGCTGGGTTGTGTTCTCCAATTATTGTTACATGTTTCAATATTAGCATATAAAAA

hide sequence

RefSeq Acc Id:

XM_039082988 ⟹ XP_038938916

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	9	48,033,541 - 48,053,876 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_579849	(Get FASTA)	NCBI Sequence Viewer
	XP_017452293	(Get FASTA)	NCBI Sequence Viewer
	XP_038938916	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD00260	(Get FASTA)	NCBI Sequence Viewer
	AAK77858	(Get FASTA)	NCBI Sequence Viewer
	EDL99122	(Get FASTA)	NCBI Sequence Viewer
	Q923U9	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_579849 ⟸ NM_133315

- UniProtKB:

Q923U9 (UniProtKB/Swiss-Prot), G3V6H7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTKSRDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVY
GLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLNMYHGWV
LTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAV
GQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALKVEESELKQLTSPKDTE
PKPLEGTHLMGEKDSNIRELECEQEPTCASQIAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMT
VLGFDCITTGYAYTQGLSGSILSVLMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCL
ILCVISVFMPGSPLDLSVSPFEDIRSRFIHEEAVSSTTKIPETEMLMSNVSNVVNTVHEMSTKS
VPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVIL
APNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFVCAPDEKEVTDESQPNTSVV

hide sequence

RefSeq Acc Id:

ENSRNOP00000005228 ⟸ ENSRNOT00000005228

RefSeq Acc Id:	XP_038938916 ⟸ XM_039082988
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_017452293 ⟸ XM_017596804
- Peptide Label:	isoform X1
- UniProtKB:	G3V6H7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTKSRDQTHQEGCCGSLANYLTSAKFLLYLGHSLSTWGDRMWHFAVSVFLVELYGNSLLLTAVY GLVVAGSVLVLGAIIGDWVDKNARLKVAQTSLVVQNVSVILCGIILMMVFLHKNELLNMYHGWV LTVCYILIITIANIANLASTATAITIQRDWIVVVAGENRSRLADMNATIRRIDQLTNILAPMAV GQIMTFGSPVIGCGFISGWNLVSMCVEYFLLWKVYQKTPALAVKAALKVEESELKQLTSPKDTE PKPLEGTHLMGEKDSNIRELECEQEPTCASQIAEPFRTFRDGWVSYYNQPVFLAGMGLAFLYMT VLGFDCITTGYAYTQGLSGSILSVLMGASAITGIMGTVAFTWLRRKCGLVRTGLFSGLAQLSCL ILCVISVFMPGSPLDLSVSPFEDIRSRFIHEEAVSSTTKIPETEMLMSNVSNVVNTVHEMSTKS VPIISVSLLFAGVIAARIGLWSFDLTVTQLLQENVIESERGIINGVQNSMNYLLDLLHFIMVIL APNPEAFGLLVLISVSFVAMGHLMYFRFAQKTLGNQIFVCAPDEKEVTDESQPNTSVV hide sequence

RefSeq Acc Id:

ENSRNOP00000086572 ⟸ ENSRNOT00000095235

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q923U9-F1-model_v2	AlphaFold	Q923U9	1-570	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620180	AgrOrtholog
BioCyc Gene	G2FUF-27634	BioCyc
Ensembl Genes	ENSRNOG00000003872	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000005228	ENTREZGENE
	ENSRNOP00000005228.3	UniProtKB/TrEMBL
	ENSRNOP00000086572.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005228	ENTREZGENE
	ENSRNOT00000005228.4	UniProtKB/TrEMBL
	ENSRNOT00000095235.1	UniProtKB/TrEMBL
Gene3D-CATH	1.20.1250.20	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Ferroportin-1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MFS_trans_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:170840	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	170840	ENTREZGENE
PANTHER	PTHR11660	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	FPN1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Slc40a1	PhenoGen
Superfamily-SCOP	SSF103473	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A631_RAT	UniProtKB/TrEMBL
	G3V6H7	ENTREZGENE, UniProtKB/TrEMBL
	Q923U9	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	Q9Z1C9	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Slc40a1	solute carrier family 40 member 1	NEWGENE_620180	solute carrier family 40 member 1	Data Merged	737654	PROVISIONAL
2016-08-02	NEWGENE_620180	solute carrier family 40 member 1			Symbol and Name status set to provisional	70820	PROVISIONAL
2016-03-09	Slc40a1	solute carrier family 40 member 1	Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-10-16	Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	Slc40a1	solute carrier family 39 (iron-regulated transporter), member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Slc40a1	solute carrier family 39 (iron-regulated transporter), member 1	Slc39a1		Symbol and Name updated	1299863	APPROVED
2002-08-07	Slc39a1	solute carrier family 39 (iron-regulated transporter), member 1			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in many specific regions of the brain	634086
gene_regulation	expression downregulated by hepcidin in an LPS-induced manner	1304454

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations