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Gene: Slc40a1 (solute carrier family 40 member 1) Rattus norvegicus
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Symbol: Slc40a1
Name: solute carrier family 40 member 1
Description: Predicted to have ferrous iron transmembrane transporter activity; identical protein binding activity; and peptide hormone binding activity. Predicted to be involved in several processes, including iron ion export across plasma membrane; iron ion homeostasis; and regulation of transcription by RNA polymerase II. Predicted to localize to the basolateral plasma membrane; cytoplasm; and nucleoplasm. Human ortholog(s) of this gene implicated in hemochromatosis type 4. Orthologous to human SLC40A1 (solute carrier family 40 member 1); PARTICIPATES IN iron efflux pathway; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CAR1; cell adhesion regulator; ferroportin 1; ferroportin-1; Fpn1; Slc11a3; Slc39a1; solute carrier family 39 (iron-regulated transporter), member 1; solute carrier family 40 (iron-regulated transporter), member 1
Orthologs:
Homo sapiens (human) : SLC40A1 (solute carrier family 40 member 1)  HGNC  Alliance
Mus musculus (house mouse) : Slc40a1 (solute carrier family 40 (iron-regulated transporter), member 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc40a1 (solute carrier family 40 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC40A1 (solute carrier family 40 member 1)
Canis lupus familiaris (dog) : SLC40A1 (solute carrier family 40 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc40a1 (solute carrier family 40 member 1)
Sus scrofa (pig) : SLC40A1 (solute carrier family 40 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0952,819,451 - 52,830,461 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0952,560,116 - 52,579,079 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4944,977,430 - 44,995,358 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1944,979,984 - 44,996,778 (-)NCBI
Celera945,700,875 - 45,718,803 (-)NCBICelera
Cytogenetic Map9q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc40a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620180
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.