Gene: Casp6 (caspase 6) Rattus norvegicus
Symbol: Casp6
Name: caspase 6
Description: ENCODES a protein that exhibits endopeptidase activity; cysteine-type endopeptidase activity involved in execution phase of apoptosis (ortholog); identical protein binding (ortholog); INVOLVED IN acute inflammatory response to non-antigenic stimulus; lens development in camera-type eye; positive regulation of apoptotic process; PARTICIPATES IN apoptotic cell death pathway; ASSOCIATED WITH Brain Ischemia; diabetes mellitus, experimental; Prostatic Neoplasms; FOUND IN cytoplasm; cytosol; nucleus; INTERACTS WITH (+)-pilocarpine; (R)-noradrenaline; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: apoptotic protease Mch-2; CASP-6; caspase-6; Mch2; MGC93335
Homo sapiens (human) : CASP6 (caspase 6)  HGNC  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Casp6 (caspase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : CASP6 (caspase 6)
Canis lupus familiaris (dog) : CASP6 (caspase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Casp6 (caspase 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02235,341,326 - 235,353,715 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02249,539,649 - 249,552,032 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42227,361,538 - 227,373,844 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12227,348,217 - 227,360,523 (+)NCBI
Celera2210,748,422 - 210,760,763 (+)NCBICelera
Cytogenetic Map2q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Casp6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70967
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE