Idh3g (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma) - Rat Genome Database
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Gene: Idh3g (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma) Rattus norvegicus
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Symbol: Idh3g
Name: isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
RGD ID: 2863
Description: Exhibits isocitrate dehydrogenase (NAD+) activity. Involved in several processes, including NADH metabolic process; carboxylic acid metabolic process; and tricarboxylic acid cycle. Predicted to localize to mitochondrion and nucleolus. Orthologous to human IDH3G (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria pathway; mitochondrial complex II deficiency pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: IDH; isocitrate dehydrogenase (NAD(+)) 3 gamma; isocitrate dehydrogenase 3 (NAD), gamma; isocitrate dehydrogenase 3 (NAD+) gamma; isocitrate dehydrogenase 3 (NAD+), gamma; isocitrate dehydrogenase 3, gamma; isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial; isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial; isocitric dehydrogenase subunit gamma; MGC94551; NAD (H)-specific isocitrate dehydrogenase gamma subunit; NAD(+)-specific ICDH subunit gamma; NAD+-isocitrate dehydrogenase gamma subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X151,515,244 - 151,524,175 (-)NCBI
Rnor_6.0 EnsemblX156,999,826 - 157,008,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,999,803 - 157,008,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,747,878 - 152,757,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,701,345 - 159,710,254 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X159,776,446 - 159,785,611 (-)NCBI
Celera1136,365,515 - 136,374,301 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:2605193   PMID:9286695   PMID:12477932   PMID:14651853   PMID:18614015   PMID:25931508   PMID:28098230   PMID:29476059   PMID:31505169  


Genomics

Comparative Map Data
Idh3g
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X151,515,244 - 151,524,175 (-)NCBI
Rnor_6.0 EnsemblX156,999,826 - 157,008,733 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,999,803 - 157,008,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,747,878 - 152,757,622 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X159,701,345 - 159,710,254 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X159,776,446 - 159,785,611 (-)NCBI
Celera1136,365,515 - 136,374,301 (+)NCBICelera
Cytogenetic MapXq37NCBI
IDH3G
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX153,785,766 - 153,794,523 (-)EnsemblGRCh38hg38GRCh38
GRCh38X153,785,768 - 153,794,375 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,051,223 - 153,059,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,704,415 - 152,713,161 (-)NCBINCBI36hg18NCBI36
Build 34X152,572,067 - 152,580,814NCBI
CeleraX153,284,902 - 153,293,648 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX141,708,249 - 141,717,006 (-)NCBIHuRef
CHM1_1X152,925,630 - 152,934,387 (-)NCBICHM1_1
Idh3g
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X72,822,569 - 72,830,503 (-)NCBIGRCm39mm39
GRCm39 EnsemblX72,822,569 - 72,830,503 (-)Ensembl
GRCm38X73,778,963 - 73,786,897 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX73,778,963 - 73,786,897 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X71,024,302 - 71,032,236 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,031,683 - 70,039,617 (-)NCBImm8
CeleraX65,031,236 - 65,039,170 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.41NCBI
Idh3g
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580500,825 - 507,608 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580500,712 - 507,512 (-)NCBIChiLan1.0ChiLan1.0
IDH3G
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,222,309 - 153,231,135 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,222,309 - 153,231,135 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X143,336,460 - 143,345,274 (-)NCBIMhudiblu_PPA_v0panPan3
IDH3G
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X121,599,368 - 121,608,707 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX121,599,368 - 121,608,643 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX106,928,530 - 106,937,871 (-)NCBI
ROS_Cfam_1.0X124,740,839 - 124,750,181 (-)NCBI
UMICH_Zoey_3.1X120,510,113 - 120,519,453 (-)NCBI
UNSW_CanFamBas_1.0X123,025,113 - 123,034,451 (-)NCBI
UU_Cfam_GSD_1.0X122,787,308 - 122,796,645 (-)NCBI
Idh3g
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_ltri_2X118,928,456 - 118,937,516 (-)NCBI
SpeTri2.0NW_004936809666,231 - 675,279 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IDH3G
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,528,644 - 124,538,298 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,528,643 - 124,537,570 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X142,093,229 - 142,102,047 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IDH3G
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,212,660 - 128,221,637 (-)NCBI
Idh3g
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946465,832 - 472,259 (-)NCBI


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X134627816159970021Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118715462159970021Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:141
Count of miRNA genes:120
Interacting mature miRNAs:125
Transcripts:ENSRNOT00000056382
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229551 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229553 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006229554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC096338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC083688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U63009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X74125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000081819   ⟹   ENSRNOP00000073128
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX156,999,826 - 157,008,733 (+)Ensembl
RefSeq Acc Id: NM_031551   ⟹   NP_113739
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X151,515,244 - 151,524,155 (-)NCBI
Rnor_6.0X156,999,826 - 157,008,735 (+)NCBI
Rnor_5.01152,747,878 - 152,757,622 (+)NCBI
RGSC_v3.4X159,701,345 - 159,710,254 (-)RGD
Celera1136,365,515 - 136,374,301 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229551   ⟹   XP_006229613
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X151,515,244 - 151,524,166 (-)NCBI
Rnor_6.0X156,999,890 - 157,008,735 (+)NCBI
Rnor_5.01152,747,878 - 152,757,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229552   ⟹   XP_006229614
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X151,515,244 - 151,524,175 (-)NCBI
Rnor_6.0X156,999,803 - 157,008,735 (+)NCBI
Rnor_5.01152,747,878 - 152,757,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229553   ⟹   XP_006229615
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X151,515,244 - 151,524,147 (-)NCBI
Rnor_6.0X156,999,850 - 157,008,735 (+)NCBI
Rnor_5.01152,747,878 - 152,757,622 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229554   ⟹   XP_006229616
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X151,515,244 - 151,524,147 (-)NCBI
Rnor_6.0X156,999,874 - 157,008,735 (+)NCBI
Rnor_5.01152,747,878 - 152,757,622 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_113739   ⟸   NM_031551
- Peptide Label: precursor
- UniProtKB: Q5XIJ3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229614   ⟸   XM_006229552
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006229615   ⟸   XM_006229553
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006229616   ⟸   XM_006229554
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006229613   ⟸   XM_006229551
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000073128   ⟸   ENSRNOT00000081819
Protein Domains
Iso_dh

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702055
Promoter ID:EPDNEW_R12579
Type:initiation region
Name:Idh3g_1
Description:isocitrate dehydrogenase 3 , gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X156,999,846 - 156,999,906EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2863 AgrOrtholog
Ensembl Genes ENSRNOG00000055572 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073128 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000081819 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7189278 IMAGE-MGC_LOAD
InterPro IsoCit/isopropylmalate_DH_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Isocitrate_DH_NAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IsoPropMal-DH-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25179 UniProtKB/TrEMBL
MGC_CLONE MGC:94551 IMAGE-MGC_LOAD
NCBI Gene 25179 ENTREZGENE
Pfam Iso_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Idh3g PhenoGen
PROSITE IDH_IMDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Iso_dh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs mito_nad_idh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt IDHG1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5XIJ3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary P70577 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-08 Idh3g  isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma  Idh3g  isocitrate dehydrogenase (NAD(+)) 3 gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2019-04-29 Idh3g  isocitrate dehydrogenase (NAD(+)) 3 gamma  Idh3g  isocitrate dehydrogenase 3 (NAD), gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Idh3g  isocitrate dehydrogenase 3 (NAD), gamma    isocitrate dehydrogenase 3, gamma  Name updated 1299863 APPROVED
2002-11-06 Idh3g  isocitrate dehydrogenase 3, gamma    isocitrate dehydrogenase 3 (NAD+), gamma  Name updated 625702 APPROVED
2001-10-23 Idh3g  NAD (H)-specific isocitrate dehydrogenase gamma subunit      Name withdrawn 68913 WITHDRAWN
2001-10-23 Idh3g  isocitrate dehydrogenase 3 (NAD+), gamma      Name updated to reflect Human and Mouse nomenclature 68913 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression isolated from the rat epididymis 633073
gene_homology sequence similar to the pig heart enzyme 633073