Mapkap1 (MAPK associated protein 1) - Rat Genome Database

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Gene: Mapkap1 (MAPK associated protein 1) Rattus norvegicus
Analyze
Symbol: Mapkap1
Name: MAPK associated protein 1
RGD ID: 1305363
Description: Predicted to enable enzyme binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phospholipid binding activity. Predicted to be involved in several processes, including TORC2 signaling; positive regulation of peptidyl-serine phosphorylation; and substantia nigra development. Predicted to be located in Golgi apparatus; cytosol; and nucleoplasm. Predicted to be part of TORC2 complex. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human MAPKAP1 (MAPK associated protein 1); PARTICIPATES IN mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100912221; LOC296648; mitogen-activated protein kinase 2-associated protein 1; mitogen-activated protein kinase associated protein 1; SAPK-interacting protein 1; stress-activated map kinase-interacting protein 1; target of rapamycin complex 2 subunit MAPKAP1; target of rapamycin complex 2 subunit MAPKAP1-like; TORC2 subunit MAPKAP1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2317,715,813 - 17,918,387 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl317,715,834 - 17,918,384 (+)Ensembl
Rnor_6.0313,484,952 - 13,701,772 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl313,484,838 - 13,701,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0318,808,956 - 19,022,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4313,439,919 - 13,643,105 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1313,336,290 - 13,539,477 (+)NCBI
Celera312,437,407 - 12,639,132 (+)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. mTOR signaling in growth control and disease. Laplante M and Sabatini DM, Cell. 2012 Apr 13;149(2):274-93. doi: 10.1016/j.cell.2012.03.017.
4. Molecular mechanisms of mTOR-mediated translational control. Ma XM and Blenis J, Nat Rev Mol Cell Biol. 2009 May;10(5):307-18. Epub 2009 Apr 2.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:12477932   PMID:16962653   PMID:17303383   PMID:21177249   PMID:22926577  


Genomics

Comparative Map Data
Mapkap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2317,715,813 - 17,918,387 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl317,715,834 - 17,918,384 (+)Ensembl
Rnor_6.0313,484,952 - 13,701,772 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl313,484,838 - 13,701,757 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0318,808,956 - 19,022,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4313,439,919 - 13,643,105 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1313,336,290 - 13,539,477 (+)NCBI
Celera312,437,407 - 12,639,132 (+)NCBICelera
Cytogenetic Map3p11NCBI
MAPKAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389125,437,394 - 125,707,208 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl9125,437,393 - 125,707,234 (-)EnsemblGRCh38hg38GRCh38
GRCh379128,199,673 - 128,469,487 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369127,239,494 - 127,509,334 (-)NCBINCBI36hg18NCBI36
Build 349125,279,226 - 125,549,067NCBI
Celera998,848,793 - 99,118,649 (-)NCBI
Cytogenetic Map9q33.3NCBI
HuRef997,812,310 - 98,082,113 (-)NCBIHuRef
CHM1_19128,349,298 - 128,620,475 (-)NCBICHM1_1
T2T-CHM13v2.09137,636,609 - 137,907,172 (-)NCBI
Mapkap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39234,296,783 - 34,514,970 (+)NCBIGRCm39mm39
GRCm39 Ensembl234,296,783 - 34,514,962 (+)Ensembl
GRCm38234,406,771 - 34,624,958 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl234,406,771 - 34,624,950 (+)EnsemblGRCm38mm10GRCm38
MGSCv37234,287,545 - 34,480,470 (+)NCBIGRCm37mm9NCBIm37
MGSCv36234,254,034 - 34,446,959 (+)NCBImm8
Celera234,129,582 - 34,324,469 (+)NCBICelera
Cytogenetic Map2BNCBI
Mapkap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554192,657,741 - 2,888,607 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554192,656,662 - 2,887,505 (+)NCBIChiLan1.0ChiLan1.0
MAPKAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.19125,072,133 - 125,336,658 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9125,072,137 - 125,336,658 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0996,561,157 - 96,825,478 (-)NCBIMhudiblu_PPA_v0panPan3
MAPKAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1957,447,115 - 57,699,979 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl957,446,832 - 57,699,950 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha956,647,161 - 56,899,816 (+)NCBI
ROS_Cfam_1.0958,367,505 - 58,620,300 (+)NCBI
ROS_Cfam_1.0 Ensembl958,367,243 - 58,621,463 (+)Ensembl
UMICH_Zoey_3.1957,125,622 - 57,378,510 (+)NCBI
UNSW_CanFamBas_1.0957,442,229 - 57,694,786 (+)NCBI
UU_Cfam_GSD_1.0957,533,163 - 57,785,902 (+)NCBI
Mapkap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947193,742,076 - 193,974,492 (-)NCBI
SpeTri2.0NW_00493648713,511,632 - 13,743,022 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPKAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1266,096,193 - 266,346,210 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11266,096,192 - 266,346,384 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21299,839,408 - 299,978,749 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAPKAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11212,441,135 - 12,706,465 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1212,441,150 - 12,707,804 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660793,412,160 - 3,680,198 (-)NCBIVero_WHO_p1.0
Mapkap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247609,587,926 - 9,829,680 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247609,588,021 - 9,828,045 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D3Rat192  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,749,162 - 17,749,521 (+)MAPPERmRatBN7.2
Rnor_6.0313,518,256 - 13,518,613NCBIRnor6.0
Rnor_5.0318,842,298 - 18,842,655UniSTSRnor5.0
RGSC_v3.4313,473,199 - 13,473,556UniSTSRGSC3.4
RGSC_v3.1313,369,570 - 13,369,928RGD
Celera312,470,687 - 12,470,922UniSTS
SHRSP x BN Map34.6199UniSTS
SHRSP x BN Map34.6199RGD
Cytogenetic Map3p11UniSTS
RH125848  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,752,015 - 17,752,260 (+)MAPPERmRatBN7.2
Rnor_6.0313,521,108 - 13,521,352NCBIRnor6.0
Rnor_5.0318,845,150 - 18,845,394UniSTSRnor5.0
RGSC_v3.4313,476,051 - 13,476,295UniSTSRGSC3.4
Celera312,473,417 - 12,473,661UniSTS
Cytogenetic Map3p11UniSTS
RH130453  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,917,086 - 17,917,302 (+)MAPPERmRatBN7.2
Rnor_6.0313,700,471 - 13,700,686NCBIRnor6.0
Rnor_5.0319,021,671 - 19,021,886UniSTSRnor5.0
RGSC_v3.4313,642,817 - 13,643,032UniSTSRGSC3.4
Celera312,638,844 - 12,639,059UniSTS
RH 3.4 Map3135.8UniSTS
Cytogenetic Map3p11UniSTS
RH143519  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2317,716,585 - 17,716,720 (+)MAPPERmRatBN7.2
Rnor_6.0313,485,688 - 13,485,822NCBIRnor6.0
Rnor_5.0318,809,730 - 18,809,864UniSTSRnor5.0
RGSC_v3.4313,440,627 - 13,440,761UniSTSRGSC3.4
Celera312,438,115 - 12,438,249UniSTS
RH 3.4 Map3145.0UniSTS
Cytogenetic Map3p11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:52
Count of miRNA genes:48
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000023889
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 42 57 41 19 41 8 11 74 35 41 11 8
Low 1
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006233950 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761722 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039104769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC079073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000023889   ⟹   ENSRNOP00000023889
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl317,715,834 - 17,918,384 (+)Ensembl
Rnor_6.0 Ensembl313,484,838 - 13,701,757 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116389   ⟹   ENSRNOP00000091071
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl317,715,885 - 17,917,373 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000119554   ⟹   ENSRNOP00000078499
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl317,715,848 - 17,917,375 (+)Ensembl
RefSeq Acc Id: NM_001011964   ⟹   NP_001011964
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,878 - 17,917,375 (+)NCBI
Rnor_6.0313,484,980 - 13,700,759 (+)NCBI
Rnor_5.0318,808,956 - 19,022,969 (+)NCBI
RGSC_v3.4313,439,919 - 13,643,105 (+)RGD
Celera312,437,407 - 12,639,132 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233949   ⟹   XP_006234011
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,850 - 17,917,375 (+)NCBI
Rnor_6.0313,484,952 - 13,701,772 (+)NCBI
Rnor_5.0318,808,956 - 19,022,969 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006233950   ⟹   XP_006234012
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,840 - 17,917,375 (+)NCBI
Rnor_6.0313,484,952 - 13,701,772 (+)NCBI
Rnor_5.0318,808,956 - 19,022,969 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008761721   ⟹   XP_008759943
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,850 - 17,918,387 (+)NCBI
Rnor_6.0313,484,952 - 13,701,772 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008761722   ⟹   XP_008759944
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,850 - 17,918,387 (+)NCBI
Rnor_6.0313,484,952 - 13,701,772 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591654   ⟹   XP_017447143
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,844 - 17,918,387 (+)NCBI
Rnor_6.0313,484,952 - 13,701,772 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591656   ⟹   XP_017447145
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,850 - 17,918,387 (+)NCBI
Rnor_6.0313,484,952 - 13,701,772 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039104765   ⟹   XP_038960693
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,813 - 17,917,375 (+)NCBI
RefSeq Acc Id: XM_039104766   ⟹   XP_038960694
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,885 - 17,917,373 (+)NCBI
RefSeq Acc Id: XM_039104768   ⟹   XP_038960696
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,850 - 17,918,387 (+)NCBI
RefSeq Acc Id: XM_039104769   ⟹   XP_038960697
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2317,715,850 - 17,849,188 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001011964   ⟸   NM_001011964
- UniProtKB: Q6AYF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006234011   ⟸   XM_006233949
- Peptide Label: isoform X1
- UniProtKB: Q6AYF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006234012   ⟸   XM_006233950
- Peptide Label: isoform X1
- UniProtKB: Q6AYF1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_008759943   ⟸   XM_008761721
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008759944   ⟸   XM_008761722
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447143   ⟸   XM_017591654
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017447145   ⟸   XM_017591656
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSRNOP00000023889   ⟸   ENSRNOT00000023889
RefSeq Acc Id: XP_038960693   ⟸   XM_039104765
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038960696   ⟸   XM_039104768
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038960697   ⟸   XM_039104769
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038960694   ⟸   XM_039104766
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000078499   ⟸   ENSRNOT00000119554
RefSeq Acc Id: ENSRNOP00000091071   ⟸   ENSRNOT00000116389

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6AYF1-F1-model_v2 AlphaFold Q6AYF1 1-522 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692004
Promoter ID:EPDNEW_R2529
Type:initiation region
Name:Mapkap1_1
Description:mitogen-activated protein kinase associated protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0313,484,950 - 13,485,010EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305363 AgrOrtholog
BioCyc Gene G2FUF-50084 BioCyc
Ensembl Genes ENSRNOG00000017583 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000078499 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000091071 ENTREZGENE
  ENSRNOP00000091071.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000116389 ENTREZGENE
  ENSRNOT00000116389.1 UniProtKB/TrEMBL
  ENSRNOT00000119554 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.30.29.30 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7122012 IMAGE-MGC_LOAD
InterPro CRIM_dom UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  Sin1/Avo1 UniProtKB/Swiss-Prot
  Sin1_N UniProtKB/Swiss-Prot
  Sin1_PH_dom UniProtKB/Swiss-Prot
KEGG Report rno:296648 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94027 IMAGE-MGC_LOAD
NCBI Gene 296648 ENTREZGENE
PANTHER PTHR13335 UniProtKB/Swiss-Prot
Pfam CRIM UniProtKB/Swiss-Prot
  SIN1 UniProtKB/Swiss-Prot
  SIN1_PH UniProtKB/Swiss-Prot
PhenoGen Mapkap1 PhenoGen
UniProt A0A8I6AEY0_RAT UniProtKB/TrEMBL
  Q6AYF1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Mapkap1  MAPK associated protein 1  LOC100912221  target of rapamycin complex 2 subunit MAPKAP1-like  Data Merged 737654 PROVISIONAL
2019-08-08 Mapkap1  MAPK associated protein 1  Mapkap1  mitogen-activated protein kinase associated protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100912221  target of rapamycin complex 2 subunit MAPKAP1-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Mapkap1  mitogen-activated protein kinase associated protein 1  Mapkap1_predicted  mitogen-activated protein kinase associated protein 1 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Mapkap1_predicted  mitogen-activated protein kinase associated protein 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED