Cdk14 (cyclin-dependent kinase 14) - Rat Genome Database

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Gene: Cdk14 (cyclin-dependent kinase 14) Rattus norvegicus
Analyze
Symbol: Cdk14
Name: cyclin-dependent kinase 14
RGD ID: 1305544
Description: Predicted to enable cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity. Predicted to be involved in G2/M transition of mitotic cell cycle and regulation of canonical Wnt signaling pathway. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be part of cytoplasmic cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytosol and nucleus. Orthologous to human CDK14 (cyclin dependent kinase 14); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: cell division protein kinase 14; LOC362316; PFTAIRE protein kinase 1; Pftk1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2428,666,416 - 29,258,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx433,637,510 - 34,219,606 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0429,563,603 - 30,145,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0427,961,326 - 28,553,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0425,825,567 - 26,419,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl425,825,567 - 26,419,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0425,732,184 - 26,326,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,352,280 - 25,942,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1425,442,897 - 25,950,147 (+)NCBI
Celera424,108,211 - 24,692,789 (+)NCBICelera
Cytogenetic Map4q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-Nitrobenzanthrone  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
aldrin  (ISO)
all-trans-retinoic acid  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chrysene  (ISO)
cisplatin  (EXP,ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP)
dexamethasone  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
ketamine  (EXP)
L-methionine  (ISO)
mercury dichloride  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
methoxychlor  (EXP)
N,N-diethyl-m-toluamide  (EXP)
nickel sulfate  (ISO)
O-methyleugenol  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
permethrin  (EXP)
potassium chromate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thimerosal  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
WIN 55212-2  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9202329   PMID:12477932   PMID:19524571   PMID:20059949   PMID:25355490  


Genomics

Comparative Map Data
Cdk14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2428,666,416 - 29,258,865 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx433,637,510 - 34,219,606 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0429,563,603 - 30,145,717 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0427,961,326 - 28,553,751 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0425,825,567 - 26,419,443 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl425,825,567 - 26,419,127 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0425,732,184 - 26,326,437 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4425,352,280 - 25,942,686 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1425,442,897 - 25,950,147 (+)NCBI
Celera424,108,211 - 24,692,789 (+)NCBICelera
Cytogenetic Map4q13NCBI
CDK14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38790,596,321 - 91,210,590 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl790,466,424 - 91,210,590 (+)EnsemblGRCh38hg38GRCh38
GRCh37790,225,635 - 90,839,905 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36790,176,648 - 90,677,840 (+)NCBINCBI36Build 36hg18NCBI36
Build 34789,983,362 - 90,484,555NCBI
Celera785,042,762 - 85,544,656 (+)NCBICelera
Cytogenetic Map7q21.13NCBI
HuRef784,947,123 - 85,448,005 (+)NCBIHuRef
CHM1_1790,268,779 - 90,769,796 (+)NCBICHM1_1
T2T-CHM13v2.0791,844,591 - 92,458,441 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2789,669,510 - 90,170,369 (+)NCBI
Cdk14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3954,853,384 - 5,430,251 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl54,853,391 - 5,470,312 (-)EnsemblGRCm39 Ensembl
GRCm3854,803,384 - 5,380,251 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl54,803,391 - 5,420,312 (-)EnsemblGRCm38mm10GRCm38
MGSCv3754,803,385 - 5,380,251 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3654,809,739 - 5,386,203 (-)NCBIMGSCv36mm8
Celera54,734,602 - 5,327,038 (-)NCBICelera
Cytogenetic Map5A1NCBI
cM Map52.61NCBI
Cdk14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554327,787,600 - 8,335,726 (+)NCBIChiLan1.0ChiLan1.0
CDK14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan17156,729,606 - 157,368,900 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0782,609,791 - 83,216,851 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1796,210,658 - 96,817,952 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl796,211,305 - 96,731,767 (+)Ensemblpanpan1.1panPan2
CDK14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11416,286,052 - 17,007,482 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1416,440,383 - 17,005,727 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1415,856,255 - 16,577,650 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01416,091,672 - 16,813,278 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1416,091,632 - 16,813,272 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11416,253,435 - 16,975,449 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01415,971,943 - 16,693,084 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01416,256,758 - 16,978,996 (+)NCBIUU_Cfam_GSD_1.0
Cdk14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511829,864,363 - 30,422,617 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366212,946,035 - 3,504,306 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049366213,030,964 - 3,504,294 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDK14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl970,499,873 - 71,310,250 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1970,678,012 - 71,310,253 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2977,577,356 - 77,865,580 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDK14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12157,752,126 - 58,434,621 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2157,751,721 - 58,335,258 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604245,792,805 - 46,481,681 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdk14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248092,155,554 - 2,688,759 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248092,067,985 - 2,688,847 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cdk14
2465 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:889
Count of miRNA genes:316
Interacting mature miRNAs:431
Transcripts:ENSRNOT00000009417
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641905Colcr1Colorectal carcinoma resistance QTL 14.30.0003intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)4129494328Rat
61333Gluco16Glucose level QTL 164.30.00001adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)4130372989Rat
9589097Slep11Serum leptin concentration QTL 115.090.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)4131934116Rat
8552903Pigfal2Plasma insulin-like growth factor 1 level QTL 27.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)4131934116Rat
9589046Scfw2Subcutaneous fat weight QTL 25.540.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)4131934116Rat
9590100Sffal4Serum free fatty acids level QTL 47.360.05blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)4131934116Rat
738021Hcar13Hepatocarcinoma resistance QTL 134.3liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)4132584199Rat
1357341Gluco5Glucose level QTL 56.4adipocyte free fatty acid secretion trait (VT:0010465)absolute change in adipocyte free fatty acid secretion per unit volume (CMO:0001446)4133250345Rat
1357343Gluco4Glucose level QTL 40.00002adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake to basal glucose uptake ratio (CMO:0000874)4133250345Rat
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
1358201Gluco12Glucose level QTL121.6adipocyte glucose uptake trait (VT:0004185)adipocyte maximal glucose uptake (CMO:0000870)4521839229593287Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
8552803Bw144Body weight QTL 14416body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)42271068534430484Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat

Markers in Region
ECD02012  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2428,828,189 - 28,829,145 (+)MAPPERmRatBN7.2
Rnor_6.0425,989,325 - 25,990,280NCBIRnor6.0
Rnor_5.0425,892,494 - 25,893,449UniSTSRnor5.0
RGSC_v3.4425,515,050 - 25,516,005UniSTSRGSC3.4
Celera424,269,092 - 24,270,047UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110091  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,177,478 - 29,177,704 (+)MAPPERmRatBN7.2
Rnor_6.0426,338,060 - 26,338,285NCBIRnor6.0
Rnor_5.0426,245,062 - 26,245,287UniSTSRnor5.0
RGSC_v3.4425,861,619 - 25,861,844UniSTSRGSC3.4
Celera424,611,797 - 24,612,022UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110146  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,189,877 - 29,190,114 (+)MAPPERmRatBN7.2
Rnor_6.0426,350,459 - 26,350,695NCBIRnor6.0
Rnor_5.0426,257,461 - 26,257,697UniSTSRnor5.0
RGSC_v3.4425,874,018 - 25,874,254UniSTSRGSC3.4
Celera424,624,196 - 24,624,432UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,250,640 - 29,250,907 (+)MAPPERmRatBN7.2
Rnor_6.0426,411,219 - 26,411,485NCBIRnor6.0
Rnor_5.0426,318,213 - 26,318,479UniSTSRnor5.0
RGSC_v3.4425,934,778 - 25,935,044UniSTSRGSC3.4
Celera424,684,881 - 24,685,147UniSTS
Cytogenetic Map4q12-q13UniSTS
REN110453  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2429,250,895 - 29,251,139 (+)MAPPERmRatBN7.2
Rnor_6.0426,411,474 - 26,411,717NCBIRnor6.0
Rnor_5.0426,318,468 - 26,318,711UniSTSRnor5.0
RGSC_v3.4425,935,033 - 25,935,276UniSTSRGSC3.4
Celera424,685,136 - 24,685,379UniSTS
Cytogenetic Map4q12-q13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 9 6 4 6 1 1 74 35 35 11 1
Low 3 48 35 15 35 7 10 6 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC111275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC114459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC126960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC141150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000009417   ⟹   ENSRNOP00000009417
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)Ensembl
Rnor_6.0 Ensembl425,825,567 - 26,419,127 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000094279   ⟹   ENSRNOP00000082191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl428,785,029 - 29,258,861 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116950   ⟹   ENSRNOP00000087492
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl428,666,843 - 29,258,861 (+)Ensembl
RefSeq Acc Id: NM_001395582   ⟹   NP_001382511
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,666,416 - 29,258,865 (+)NCBI
RefSeq Acc Id: NM_001395583   ⟹   NP_001382512
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,666,416 - 29,191,598 (+)NCBI
RefSeq Acc Id: NM_001395584   ⟹   NP_001382513
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,785,024 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_039107757   ⟹   XP_038963685
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,698,377 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_039107758   ⟹   XP_038963686
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,703,332 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_039107759   ⟹   XP_038963687
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,785,874 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_039107760   ⟹   XP_038963688
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,785,697 - 29,258,865 (+)NCBI
RefSeq Acc Id: XM_039107761   ⟹   XP_038963689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2428,700,280 - 29,258,865 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000009417   ⟸   ENSRNOT00000009417
RefSeq Acc Id: XP_038963685   ⟸   XM_039107757
- Peptide Label: isoform X2
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963689   ⟸   XM_039107761
- Peptide Label: isoform X2
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963686   ⟸   XM_039107758
- Peptide Label: isoform X2
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963688   ⟸   XM_039107760
- Peptide Label: isoform X2
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963687   ⟸   XM_039107759
- Peptide Label: isoform X2
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000087492   ⟸   ENSRNOT00000116950
RefSeq Acc Id: ENSRNOP00000082191   ⟸   ENSRNOT00000094279
RefSeq Acc Id: NP_001382511   ⟸   NM_001395582
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A7V5 (UniProtKB/TrEMBL),   D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382512   ⟸   NM_001395583
- Peptide Label: isoform 1
- UniProtKB: A0A8I6A7V5 (UniProtKB/TrEMBL),   D3ZSZ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382513   ⟸   NM_001395584
- Peptide Label: isoform 2
- UniProtKB: D3ZSZ0 (UniProtKB/TrEMBL)
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSZ0-F1-model_v2 AlphaFold D3ZSZ0 1-279 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692839
Promoter ID:EPDNEW_R3364
Type:initiation region
Name:Cdk14_1
Description:cyclin-dependent kinase 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0425,825,735 - 25,825,795EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305544 AgrOrtholog
BioCyc Gene G2FUF-45789 BioCyc
Ensembl Genes ENSRNOG00000007151 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000009417.6 UniProtKB/TrEMBL
  ENSRNOT00000094279 ENTREZGENE
  ENSRNOT00000094279.1 UniProtKB/TrEMBL
  ENSRNOT00000116950 ENTREZGENE
  ENSRNOT00000116950.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:362316 UniProtKB/TrEMBL
NCBI Gene 362316 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 14 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Cdk14 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
RatGTEx ENSRNOG00000007151 RatGTEx
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I5ZUH6_RAT UniProtKB/TrEMBL
  A0A8I6A7V5 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSZ0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Cdk14  cyclin-dependent kinase 14  Pftk1  PFTAIRE protein kinase 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pftk1  PFTAIRE protein kinase 1   Pftk1_predicted  PFTAIRE protein kinase 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pftk1_predicted  PFTAIRE protein kinase 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED