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Gene: Nras (NRAS proto-oncogene, GTPase) Rattus norvegicus
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Symbol: Nras
Name: NRAS proto-oncogene, GTPase
Description: Predicted to have GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; defense response to protozoan; and positive regulation of cell population proliferation. Predicted to localize to the Golgi apparatus and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 6; autoimmune lymphoproliferative syndrome type 4; endocrine gland cancer (multiple); epidermal nevus; and hematologic cancer (multiple). Orthologous to human NRAS (NRAS proto-oncogene, GTPase); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; epidermal growth factor/neuregulin signaling pathway; Fc epsilon receptor mediated signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-di-tert-butyl-4-methylphenol; 2-nitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: GTPase NRas; neuroblastoma ras oncogene; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; transforming protein N-Ras
Orthologs:
Homo sapiens (human) : NRAS (NRAS proto-oncogene, GTPase)  HGNC  Alliance
Mus musculus (house mouse) : Nras (neuroblastoma ras oncogene)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nras (NRAS proto-oncogene, GTPase)
Pan paniscus (bonobo/pygmy chimpanzee) : NRAS (NRAS proto-oncogene, GTPase)
Canis lupus familiaris (dog) : NRAS (NRAS proto-oncogene, GTPase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nras (NRAS proto-oncogene, GTPase)
Sus scrofa (pig) : NRAS (NRAS proto-oncogene, GTPase)
more info ...
Related Pseudogenes: Nras-ps1  
Allele / Splice: Nras-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02205,553,119 - 205,563,716 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2205,553,163 - 205,560,791 (+)Ensembl
Rnor_5.02224,983,707 - 224,994,303 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42198,292,650 - 198,300,286 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12198,255,369 - 198,265,062 (+)NCBI
Celera2183,056,304 - 183,063,940 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nras
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3205
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.