Gene: Slc1a1 (solute carrier family 1 member 1) Rattus norvegicus
Symbol: Slc1a1
Name: solute carrier family 1 member 1
Description: ENCODES a protein that exhibits glutamate binding; glutamate:sodium symporter activity; L-glutamate transmembrane transporter activity; INVOLVED IN L-glutamate transport; protein homooligomerization; chloride transmembrane transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH Atrophy (ortholog); Brain Diseases (ortholog); Cerebral Visual Impairment and Intellectual Disability (ortholog); FOUND IN apical plasma membrane (ortholog); integral component of plasma membrane (ortholog); plasma membrane (ortholog); INTERACTS WITH (+)-pilocarpine; (S)-nicotine; 1-naphthyl isothiocyanate
Type: protein-coding
Also known as: Eaac1; Eaat3; excitatory amino acid carrier 1; excitatory amino acid transporter 3; excitatory amino acid transporter-3; excitatory amino-acid carrier 1; REAAC1; sodium-dependent glutamate/aspartate transporter 3; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; Solute carrier family 1 A1 (brain glutamate transporter); solute carrier family 1, member 1
Homo sapiens (human) : SLC1A1 (solute carrier family 1 member 1)  HGNC  AGR
Mus musculus (house mouse) : Slc1a1 (solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Slc1a1 (solute carrier family 1 member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC1A1 (solute carrier family 1 member 1)
Canis lupus familiaris (dog) : SLC1A1 (solute carrier family 1 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc1a1 (solute carrier family 1 member 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01246,955,017 - 247,035,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01254,195,480 - 254,274,919 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,469,746 - 232,549,584 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11232,633,737 - 232,715,504 (+)NCBI
Celera1223,704,163 - 223,782,895 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Slc1a1
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3696
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE