Fkbp8 (FKBP prolyl isomerase 8) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Fkbp8 (FKBP prolyl isomerase 8) Rattus norvegicus
Analyze
Symbol: Fkbp8
Name: FKBP prolyl isomerase 8
RGD ID: 1308670
Description: Predicted to enable several functions, including calmodulin binding activity; disordered domain specific binding activity; and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of protein phosphorylation; protein folding; and regulation of autophagy of mitochondrion. Predicted to act upstream of or within several processes, including nervous system development; positive regulation of BMP signaling pathway; and smoothened signaling pathway. Predicted to be located in endoplasmic reticulum membrane and mitochondrion. Predicted to be part of protein-containing complex. Predicted to be active in several cellular components, including cytosol; endomembrane system; and mitochondrial envelope. Orthologous to human FKBP8 (FKBP prolyl isomerase 8); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FK506 binding protein 8; FK506 binding protein 8, 38kDa; FK506-binding protein 8; FKBP-8; LOC290652; MGC125185; peptidyl-prolyl cis-trans isomerase; peptidyl-prolyl cis-trans isomerase FKBP8; PPIase; PPIase FKBP8; rotamase
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,929,581 - 18,936,621 (-)NCBIGRCr8
mRatBN7.21618,895,608 - 18,902,648 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,893,576 - 18,902,612 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,937,354 - 18,944,324 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,070,071 - 20,077,034 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,990,316 - 18,997,286 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,645,956 - 20,652,890 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,645,957 - 20,652,889 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,501,665 - 20,508,369 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,401,883 - 19,407,192 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,401,881 - 19,408,527 (-)NCBI
Celera1619,087,049 - 19,094,012 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:15105374   PMID:15733859   PMID:17024179   PMID:18003640   PMID:18590716   PMID:18614015   PMID:19946888   PMID:26748656   PMID:29916806   PMID:31505169  


Genomics

Comparative Map Data
Fkbp8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,929,581 - 18,936,621 (-)NCBIGRCr8
mRatBN7.21618,895,608 - 18,902,648 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,893,576 - 18,902,612 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,937,354 - 18,944,324 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,070,071 - 20,077,034 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01618,990,316 - 18,997,286 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,645,956 - 20,652,890 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,645,957 - 20,652,889 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,501,665 - 20,508,369 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,401,883 - 19,407,192 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,401,881 - 19,408,527 (-)NCBI
Celera1619,087,049 - 19,094,012 (-)NCBICelera
Cytogenetic Map16p14NCBI
FKBP8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,531,763 - 18,543,573 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,531,751 - 18,544,077 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,642,573 - 18,654,383 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,503,568 - 18,515,383 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,503,567 - 18,515,383NCBI
Celera1918,544,773 - 18,556,588 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,205,047 - 18,217,230 (-)NCBIHuRef
CHM1_11918,643,053 - 18,654,863 (-)NCBICHM1_1
T2T-CHM13v2.01918,667,119 - 18,678,929 (-)NCBIT2T-CHM13v2.0
Fkbp8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,980,371 - 70,987,978 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,980,374 - 70,987,978 (+)EnsemblGRCm39 Ensembl
GRCm38870,527,721 - 70,535,328 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,527,724 - 70,535,328 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,051,642 - 73,059,227 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,458,516 - 73,464,312 (+)NCBIMGSCv36mm8
Celera873,084,164 - 73,091,753 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Fkbp8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555243,036,953 - 3,044,296 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555243,037,825 - 3,044,296 (+)NCBIChiLan1.0ChiLan1.0
FKBP8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,391,263 - 23,403,519 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,399,718 - 22,411,982 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,009,505 - 18,021,772 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11918,980,269 - 18,992,170 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1918,980,269 - 18,992,170 (-)Ensemblpanpan1.1panPan2
FKBP8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,494,856 - 44,504,084 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,489,219 - 44,598,497 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,409,560 - 44,418,774 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,981,067 - 44,990,281 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,980,688 - 44,990,281 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,218,433 - 44,227,646 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,628,579 - 44,637,790 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,904,032 - 44,913,247 (+)NCBIUU_Cfam_GSD_1.0
Fkbp8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,177,956 - 203,186,579 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,728,114 - 2,735,317 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,728,089 - 2,735,718 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FKBP8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,253,342 - 59,267,165 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,256,546 - 59,267,171 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,035,636 - 59,046,247 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FKBP8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,007,764 - 17,018,409 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,007,390 - 17,017,714 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,321,762 - 2,332,880 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fkbp8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249081,713,590 - 1,720,709 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fkbp8
18 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:76
Count of miRNA genes:62
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000027040
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat

Markers in Region
RH128354  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,895,671 - 18,895,853 (+)MAPPERmRatBN7.2
Rnor_6.01620,646,020 - 20,646,201NCBIRnor6.0
Rnor_5.01620,501,729 - 20,501,910UniSTSRnor5.0
RGSC_v3.41619,401,947 - 19,402,128UniSTSRGSC3.4
Celera1619,087,113 - 19,087,294UniSTS
RH 3.4 Map16214.6UniSTS
Cytogenetic Map16p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094327 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063275185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC107454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000077756   ⟹   ENSRNOP00000074539
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,893,576 - 18,902,612 (-)Ensembl
Rnor_6.0 Ensembl1620,645,957 - 20,652,889 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000095622   ⟹   ENSRNOP00000087668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,895,633 - 18,900,999 (-)Ensembl
RefSeq Acc Id: NM_001037180   ⟹   NP_001032257
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,543 (-)NCBI
mRatBN7.21618,895,608 - 18,902,570 (-)NCBI
Rnor_6.01620,645,956 - 20,652,890 (-)NCBI
Rnor_5.01620,501,665 - 20,508,369 (-)NCBI
RGSC_v3.41619,401,883 - 19,407,192 (-)RGD
Celera1619,087,049 - 19,094,012 (-)RGD
Sequence:
RefSeq Acc Id: XM_039094321   ⟹   XP_038950249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,581 (-)NCBI
mRatBN7.21618,895,608 - 18,902,648 (-)NCBI
RefSeq Acc Id: XM_039094322   ⟹   XP_038950250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,336 (-)NCBI
mRatBN7.21618,895,608 - 18,902,452 (-)NCBI
RefSeq Acc Id: XM_039094323   ⟹   XP_038950251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,545 (-)NCBI
mRatBN7.21618,895,608 - 18,902,600 (-)NCBI
RefSeq Acc Id: XM_039094326   ⟹   XP_038950254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,425 (-)NCBI
mRatBN7.21618,895,608 - 18,902,452 (-)NCBI
RefSeq Acc Id: XM_039094327   ⟹   XP_038950255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,621 (-)NCBI
mRatBN7.21618,895,608 - 18,902,648 (-)NCBI
RefSeq Acc Id: XM_039094328   ⟹   XP_038950256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,580 (-)NCBI
mRatBN7.21618,895,608 - 18,902,600 (-)NCBI
RefSeq Acc Id: XM_063275162   ⟹   XP_063131232
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,551 (-)NCBI
RefSeq Acc Id: XM_063275163   ⟹   XP_063131233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,621 (-)NCBI
RefSeq Acc Id: XM_063275164   ⟹   XP_063131234
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,425 (-)NCBI
RefSeq Acc Id: XM_063275165   ⟹   XP_063131235
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,296 (-)NCBI
RefSeq Acc Id: XM_063275166   ⟹   XP_063131236
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,553 (-)NCBI
RefSeq Acc Id: XM_063275167   ⟹   XP_063131237
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,320 (-)NCBI
RefSeq Acc Id: XM_063275169   ⟹   XP_063131239
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,548 (-)NCBI
RefSeq Acc Id: XM_063275170   ⟹   XP_063131240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,339 (-)NCBI
RefSeq Acc Id: XM_063275171   ⟹   XP_063131241
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,289 (-)NCBI
RefSeq Acc Id: XM_063275172   ⟹   XP_063131242
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,571 (-)NCBI
RefSeq Acc Id: XM_063275173   ⟹   XP_063131243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,621 (-)NCBI
RefSeq Acc Id: XM_063275174   ⟹   XP_063131244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,580 (-)NCBI
RefSeq Acc Id: XM_063275175   ⟹   XP_063131245
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,345 (-)NCBI
RefSeq Acc Id: XM_063275176   ⟹   XP_063131246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,550 (-)NCBI
RefSeq Acc Id: XM_063275177   ⟹   XP_063131247
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,482 (-)NCBI
RefSeq Acc Id: XM_063275178   ⟹   XP_063131248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,547 (-)NCBI
RefSeq Acc Id: XM_063275179   ⟹   XP_063131249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,320 (-)NCBI
RefSeq Acc Id: XM_063275180   ⟹   XP_063131250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,580 (-)NCBI
RefSeq Acc Id: XM_063275181   ⟹   XP_063131251
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,571 (-)NCBI
RefSeq Acc Id: XM_063275182   ⟹   XP_063131252
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,299 (-)NCBI
RefSeq Acc Id: XM_063275183   ⟹   XP_063131253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,345 (-)NCBI
RefSeq Acc Id: XM_063275184   ⟹   XP_063131254
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,563 (-)NCBI
RefSeq Acc Id: XM_063275185   ⟹   XP_063131255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,929,581 - 18,936,296 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001032257 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950249 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950250 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950251 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950254 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950255 (Get FASTA)   NCBI Sequence Viewer  
  XP_038950256 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131232 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131233 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131234 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131235 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131236 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131237 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131239 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131240 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131241 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131242 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131243 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131244 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131245 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131246 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131247 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131248 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131249 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131250 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131251 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131252 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131253 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131254 (Get FASTA)   NCBI Sequence Viewer  
  XP_063131255 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI07455 (Get FASTA)   NCBI Sequence Viewer  
  EDL90703 (Get FASTA)   NCBI Sequence Viewer  
  EDL90704 (Get FASTA)   NCBI Sequence Viewer  
  EDL90705 (Get FASTA)   NCBI Sequence Viewer  
  EDL90706 (Get FASTA)   NCBI Sequence Viewer  
  EDL90707 (Get FASTA)   NCBI Sequence Viewer  
  EDL90708 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074539
  ENSRNOP00000074539.1
  ENSRNOP00000087668.1
  ENSRNOP00055004283
  ENSRNOP00060012686
  ENSRNOP00065033619
GenBank Protein Q3B7U9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001032257   ⟸   NM_001037180
- UniProtKB: Q3B7U9 (UniProtKB/Swiss-Prot),   A0A8I6A3K9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074539   ⟸   ENSRNOT00000077756
RefSeq Acc Id: XP_038950255   ⟸   XM_039094327
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A3K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950249   ⟸   XM_039094321
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A3K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950256   ⟸   XM_039094328
- Peptide Label: isoform X8
- UniProtKB: A0A8I6A3K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950251   ⟸   XM_039094323
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A3K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950254   ⟸   XM_039094326
- Peptide Label: isoform X7
- UniProtKB: Q3B7U9 (UniProtKB/Swiss-Prot),   A0A8I6A3K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038950250   ⟸   XM_039094322
- Peptide Label: isoform X5
- UniProtKB: A0A8I6A3K9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000087668   ⟸   ENSRNOT00000095622
RefSeq Acc Id: XP_063131243   ⟸   XM_063275173
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131233   ⟸   XM_063275163
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131244   ⟸   XM_063275174
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063131250   ⟸   XM_063275180
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063131251   ⟸   XM_063275181
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063131242   ⟸   XM_063275172
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131254   ⟸   XM_063275184
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063131236   ⟸   XM_063275166
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063131232   ⟸   XM_063275162
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131246   ⟸   XM_063275176
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063131239   ⟸   XM_063275169
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131248   ⟸   XM_063275178
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063131247   ⟸   XM_063275177
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063131234   ⟸   XM_063275164
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131253   ⟸   XM_063275183
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063131245   ⟸   XM_063275175
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063131240   ⟸   XM_063275170
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063131249   ⟸   XM_063275179
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063131237   ⟸   XM_063275167
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063131252   ⟸   XM_063275182
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063131255   ⟸   XM_063275185
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063131235   ⟸   XM_063275165
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063131241   ⟸   XM_063275171
- Peptide Label: isoform X3
Protein Domains
PPIase FKBP-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3B7U9-F1-model_v2 AlphaFold Q3B7U9 1-403 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700026
Promoter ID:EPDNEW_R10549
Type:multiple initiation site
Name:Fkbp8_1
Description:FK506 binding protein 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,652,925 - 20,652,985EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308670 AgrOrtholog
BioCyc Gene G2FUF-11785 BioCyc
Ensembl Genes ENSRNOG00000058359 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055003640 UniProtKB/Swiss-Prot
  ENSRNOG00060009606 UniProtKB/Swiss-Prot
  ENSRNOG00065024000 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000077756 ENTREZGENE
  ENSRNOT00000077756.2 UniProtKB/Swiss-Prot
  ENSRNOT00000095622.1 UniProtKB/TrEMBL
  ENSRNOT00055005707 UniProtKB/Swiss-Prot
  ENSRNOT00060016239 UniProtKB/Swiss-Prot
  ENSRNOT00065041170 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.10.50.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7378812 IMAGE-MGC_LOAD
InterPro PPIase_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PPIase_FKBP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:290652 UniProtKB/Swiss-Prot
MGC_CLONE MGC:125185 IMAGE-MGC_LOAD
NCBI Gene 290652 ENTREZGENE
PANTHER PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PEPTIDYLPROLYL ISOMERASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FKBP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fkbp8 PhenoGen
PROSITE FKBP_PPIASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058359 RatGTEx
  ENSRNOG00055003640 RatGTEx
  ENSRNOG00060009606 RatGTEx
  ENSRNOG00065024000 RatGTEx
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP FKBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A3K9 ENTREZGENE, UniProtKB/TrEMBL
  A6KA29_RAT UniProtKB/TrEMBL
  A6KA30_RAT UniProtKB/TrEMBL
  A6KA33_RAT UniProtKB/TrEMBL
  FKBP8_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-11-09 Fkbp8  FKBP prolyl isomerase 8  Fkbp8  FK506 binding protein 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-10-22 Fkbp8  FK506 binding protein 8  Fkbp8  FK506 binding protein 8, 38kDa  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Fkbp8  FK506 binding protein 8, 38kDa  Fkbp8  FK506 binding protein 8  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Fkbp8  FK506 binding protein 8  Fkbp8_predicted  FK506 binding protein 8 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Fkbp8_predicted  FK506 binding protein 8 (predicted)      Symbol and Name status set to approved 70820 APPROVED