 Gene-Chemical Interaction Annotations | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations |
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Analyze GeneStrainQTL List |
 Gene Annotator (Functional Annotation) unavailable |
 Gene Annotator (Annotation Distribution) unavailable |
 Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable |
Gene Annotator (Functional Annotation) |
Gene Annotator (Annotation Distribution) |
Variant Visualizer (Genomic Variants) |
 InterViewer (Protein-Protein Interactions) unavailable |
 Gviewer (Genome Viewer) unavailable |
 Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable |
InterViewer (Protein-Protein Interactions) |
GViewer (Genome Viewer) |
Variant Visualizer (Damaging Variants) |
 Gene Annotator (Annotation Comparison) unavailable |
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Gene Annotator (Annotation Comparison) |
OLGA (Gene List Generator) |
Excel (Download) |
 MOET (Multi-Ontology Enrichement) unavailable |
 GOLF (Gene-Ortholog Location Finder) unavailable |
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MOET (Multi-Ontology Enrichement) |
GOLF (Gene-Ortholog Location Finder) |
Gene Ontology AnnotationsDisease Annotations
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Gene-Chemical Interaction Annotations
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Gene Ontology AnnotationsBiological Process
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Cellular Component
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Molecular Function
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References - curated| 1. | GOA data from the GO Consortium |
| 2. | MGD data from the GO Consortium |
| 3. | RGD automated data pipeline |
| 4. | RGD automated import pipeline for gene-chemical interactions |
References - uncuratedGenomics
Comparative Map Data| Fkbp8 (Rattus norvegicus - Norway rat) |
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| FKBP8 (Homo sapiens - human) |
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| Fkbp8 (Mus musculus - house mouse) |
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| Fkbp8 (Chinchilla lanigera - long-tailed chinchilla) |
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| FKBP8 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| FKBP8 (Canis lupus familiaris - dog) |
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| Fkbp8 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| FKBP8 (Sus scrofa - pig) |
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Position Markers| RH128354 |
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QTLs in Region (Rnor_6.0)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
miRNA Target Status
Predicted Target Of
| The detailed report is available here: | | Full Report | | CSV | | TAB | | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
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Expression
RNA-SEQ ExpressionHigh: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM
| testis | heart | brain | ovary | uterus | skeletal muscle tissue | colon | gastrocnemius | forebrain | hindbrain | lung | spleen | liver | kidney | adrenal gland | thymus | |
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| High | ||||||||||||||||
| Medium | 22 | 43 | 23 | 15 | 4 | 3 | 3 | 8 | 26 | 25 | 11 | 11 | 41 | 35 | 8 | 8 |
| Low | ||||||||||||||||
| Below cutoff |
View RNA-SEQ Expression Data
Sequence
Nucleotide Sequences| RefSeq Transcripts | NM_001037180 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR07024877 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
| AAHX01086855 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| BC107454 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| CH474031 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ216680 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
| FQ219623 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Reference Sequences
| RefSeq Acc Id: | NM_001037180 ⟹ NP_001032257 | ||||||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||||||
| Position: |
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| Sequence: |
CTGGGGGTGGGGAGGGGGGCACAGGACCCCAAGCGGGGTCCCCAAGCCGCAGGGCCAGTTCCTGhide sequence |
Protein Sequences| Protein RefSeqs | NP_001032257 | (Get FASTA) | NCBI Sequence Viewer |
| GenBank Protein | AAI07455 | (Get FASTA) | NCBI Sequence Viewer |
| EDL90703 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL90704 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL90705 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL90706 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL90707 | (Get FASTA) | NCBI Sequence Viewer | |
| EDL90708 | (Get FASTA) | NCBI Sequence Viewer | |
| Q3B7U9 | (Get FASTA) | NCBI Sequence Viewer |
Reference Sequences
| RefSeq Acc Id: | NP_001032257 ⟸ NM_001037180 |
| - UniProtKB: | Q3B7U9 (UniProtKB/Swiss-Prot) |
| - Sequence: |
MASWAEPSEPAAQLLCGAPLLEGFEVLDGVDDAEEEDDLSGLPPLEDMGQPTVEEAEQPGALARhide sequence |
TranscriptomePromoters| RGD ID: | 13700026 | |||||||||
| Promoter ID: | EPDNEW_R10549 | |||||||||
| Type: | multiple initiation site | |||||||||
| Name: | Fkbp8_1 | |||||||||
| Description: | FK506 binding protein 8 | |||||||||
| SO ACC ID: | SO:0000170 | |||||||||
| Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | |||||||||
| Experiment Methods: | Single-end sequencing. | |||||||||
| Position: |
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Strain Variation
Strain Sequence Variants (Rnor 6.0)
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Damaging VariantsAssembly: RGSC_v3.4
| Chromosome | Start Pos | End Pos | Reference Nucleotide | Variant Nucleotide | Variant Type | Strain |
| 16 | 19406900 | 19406901 | C | A | snv | SS/JrHsdMcwi (MCW) |
Additional Information
External Database Links| Database | Acc Id | Source(s) |
| AGR Gene | RGD:1308670 | AgrOrtholog |
| Ensembl Genes | ENSRNOG00000058359 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Protein | ENSRNOP00000074539 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Ensembl Transcript | ENSRNOT00000077756 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Gene3D-CATH | 1.25.40.10 | UniProtKB/Swiss-Prot |
| IMAGE_CLONE | IMAGE:7378812 | IMAGE-MGC_LOAD |
| InterPro | PPIase_FKBP_dom | UniProtKB/Swiss-Prot |
| TPR-contain_dom | UniProtKB/Swiss-Prot | |
| TPR-like_helical_dom_sf | UniProtKB/Swiss-Prot | |
| TPR_repeat | UniProtKB/Swiss-Prot | |
| KEGG Report | rno:290652 | UniProtKB/Swiss-Prot |
| MGC_CLONE | MGC:125185 | IMAGE-MGC_LOAD |
| NCBI Gene | 290652 | ENTREZGENE |
| Pfam | FKBP_C | UniProtKB/Swiss-Prot |
| PhenoGen | Fkbp8 | PhenoGen |
| PROSITE | FKBP_PPIASE | UniProtKB/Swiss-Prot |
| TPR | UniProtKB/Swiss-Prot | |
| TPR_REGION | UniProtKB/Swiss-Prot | |
| SMART | TPR | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | SSF48452 | UniProtKB/Swiss-Prot |
| UniGene | Rn.99789 | ENTREZGENE |
| UniProt | FKBP8_RAT | UniProtKB/Swiss-Prot, ENTREZGENE |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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| 2018-11-09 | Fkbp8 | FKBP prolyl isomerase 8 | Fkbp8 | FK506 binding protein 8 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2009-10-22 | Fkbp8 | FK506 binding protein 8 | Fkbp8 | FK506 binding protein 8, 38kDa | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2008-09-24 | Fkbp8 | FK506 binding protein 8, 38kDa | Fkbp8 | FK506 binding protein 8 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
| 2005-12-06 | Fkbp8 | FK506 binding protein 8 | Fkbp8_predicted | FK506 binding protein 8 (predicted) | Symbol and Name updated | 1559027 | APPROVED |
| 2005-01-12 | Fkbp8_predicted | FK506 binding protein 8 (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |
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| More on Fkbp8 | |
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Alliance Gene |
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NCBI Gene |
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Ensembl Gene |
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JBrowse: rn5 rn6 |
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NCBI Genome Data Viewer |
| RGD Object Information | |
| RGD ID: | 1308670 |
| Created: | 2005-01-12 |
| Species: | Rattus norvegicus |
| Last Modified: | 2019-11-27 |
| Status: | ACTIVE |
