Usp5 (ubiquitin specific peptidase 5) - Rat Genome Database

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Gene: Usp5 (ubiquitin specific peptidase 5) Rattus norvegicus
Analyze
Symbol: Usp5
Name: ubiquitin specific peptidase 5
RGD ID: 1308438
Description: Predicted to enable cysteine-type deubiquitinase activity; cysteine-type endopeptidase activity; and ubiquitin binding activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process and protein K48-linked deubiquitination. Predicted to be active in cytosol and nucleus. Orthologous to human USP5 (ubiquitin specific peptidase 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911959; LOC297593; ubiquitin carboxyl-terminal hydrolase 5; ubiquitin carboxyl-terminal hydrolase 5-like; ubiquitin specific peptidase 5 (isopeptidase T); ubiquitin specific protease 5 (isopeptidase T)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24157,619,643 - 157,634,711 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIRnor_WKY
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-cyanoalanine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetamide  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP)
bortezomib  (ISO)
Brodifacoum  (EXP)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
camptothecin  (ISO)
cannabidiol  (ISO)
capsaicin  (EXP)
chlordecone  (ISO)
clozapine  (ISO)
coumestrol  (ISO)
Cuprizon  (ISO)
cyclophosphamide  (ISO)
dioxygen  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gold atom  (ISO)
gold(0)  (ISO)
haloperidol  (ISO)
ivermectin  (ISO)
lovastatin  (ISO)
methylazoxymethanol  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
paclitaxel  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (ISO)
rac-lactic acid  (ISO)
sodium arsenite  (EXP,ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
trimellitic anhydride  (ISO)
triptonide  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
warfarin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IBA)
nucleus  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19098288   PMID:19182904   PMID:22871113   PMID:23375434   PMID:24424410  


Genomics

Comparative Map Data
Usp5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24157,619,643 - 157,634,711 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4163,847,808 - 163,862,942 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.04159,630,718 - 159,645,852 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.04158,266,340 - 158,281,358 (-)NCBIRnor_WKY
Rnor_6.04157,332,735 - 157,347,803 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,350,331 - 224,365,479 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,937,706 - 160,952,769 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4146,357,626 - 146,372,628 (-)NCBICelera
Cytogenetic Map4q42NCBI
USP5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,852,150 - 6,866,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl126,852,148 - 6,866,632 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,961,314 - 6,975,796 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,831,546 - 6,846,057 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,831,583 - 6,846,054NCBI
Celera128,578,571 - 8,593,082 (+)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef126,815,013 - 6,829,524 (+)NCBIHuRef
CHM1_1126,960,283 - 6,974,794 (+)NCBICHM1_1
T2T-CHM13v2.0126,861,449 - 6,875,929 (+)NCBIT2T-CHM13v2.0
Usp5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396124,791,982 - 124,806,447 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6124,791,982 - 124,806,447 (-)EnsemblGRCm39 Ensembl
GRCm386124,815,019 - 124,829,484 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6124,815,019 - 124,829,484 (-)EnsemblGRCm38mm10GRCm38
MGSCv376124,765,037 - 124,779,465 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366124,780,638 - 124,795,066 (-)NCBIMGSCv36mm8
Celera6126,491,148 - 126,505,576 (-)NCBICelera
Cytogenetic Map6F2NCBI
cM Map659.17NCBI
Usp5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554134,451,622 - 4,466,832 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554134,451,530 - 4,466,832 (+)NCBIChiLan1.0ChiLan1.0
USP5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1126,895,416 - 6,909,936 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,895,416 - 6,909,936 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0126,983,941 - 6,998,469 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
USP5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12738,158,850 - 38,172,689 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2738,158,834 - 38,172,071 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha278,444,116 - 8,457,897 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02738,511,741 - 38,525,542 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2738,511,746 - 38,524,959 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12738,385,805 - 38,399,013 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02738,426,829 - 38,440,619 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0277,922,848 - 7,936,630 (+)NCBIUU_Cfam_GSD_1.0
Usp5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945102,284,676 - 102,298,641 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936709952,182 - 966,498 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936709952,225 - 966,429 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
USP5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl563,843,745 - 63,858,716 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1563,843,742 - 63,858,835 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2566,279,250 - 66,294,259 (-)NCBISscrofa10.2Sscrofa10.2susScr3
USP5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1116,885,401 - 6,899,983 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl116,885,311 - 6,898,442 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660631,323,576 - 1,338,147 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Usp5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248603,519,113 - 3,532,687 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248603,519,106 - 3,532,690 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Usp5
42 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:272
Count of miRNA genes:167
Interacting mature miRNAs:186
Transcripts:ENSRNOT00000020785
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4114627026159627026Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
1581574Eae20Experimental allergic encephalomyelitis QTL 207.8nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)4153031106158841762Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat

Markers in Region
AI411387  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,619,843 - 157,620,056 (-)MAPPERmRatBN7.2
mRatBN7.24157,619,843 - 157,620,056 (+)MAPPERmRatBN7.2
Rnor_6.04157,332,936 - 157,333,148NCBIRnor6.0
Rnor_6.0920,212,509 - 20,212,721NCBIRnor6.0
Rnor_5.04224,350,532 - 224,350,744UniSTSRnor5.0
Rnor_5.0919,088,485 - 19,088,697UniSTSRnor5.0
RGSC_v3.44160,937,902 - 160,938,114UniSTSRGSC3.4
Celera4146,357,822 - 146,358,034UniSTS
RH 3.4 Map41005.8UniSTS
Cytogenetic Map4q42UniSTS
MARC_7181-7182:996687603:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24157,622,121 - 157,622,508 (-)MAPPERmRatBN7.2
mRatBN7.24157,622,121 - 157,622,508 (+)MAPPERmRatBN7.2
Rnor_6.0920,210,057 - 20,210,443NCBIRnor6.0
Rnor_6.04157,335,214 - 157,335,600NCBIRnor6.0
Rnor_5.0919,086,033 - 19,086,419UniSTSRnor5.0
Rnor_5.04224,352,810 - 224,353,196UniSTSRnor5.0
RGSC_v3.44160,940,180 - 160,940,566UniSTSRGSC3.4
Celera4146,360,100 - 146,360,486UniSTS
Cytogenetic Map4q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000020785   ⟹   ENSRNOP00000020785
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,619,648 - 157,634,711 (-)Ensembl
Rnor_6.0 Ensembl4157,332,740 - 157,347,803 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109840   ⟹   ENSRNOP00000078694
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4157,619,643 - 157,634,711 (-)Ensembl
RefSeq Acc Id: NM_001106619   ⟹   NP_001100089
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,619,648 - 157,634,711 (-)NCBI
Rnor_6.04157,332,740 - 157,347,803 (-)NCBI
Rnor_5.04224,350,331 - 224,365,479 (-)NCBI
RGSC_v3.44160,937,706 - 160,952,769 (-)RGD
Celera4146,357,626 - 146,372,628 (-)RGD
Sequence:
RefSeq Acc Id: XM_006237338   ⟹   XP_006237400
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24157,619,643 - 157,634,707 (-)NCBI
Rnor_6.04157,332,735 - 157,347,800 (-)NCBI
Rnor_5.04224,350,331 - 224,365,479 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001100089 (Get FASTA)   NCBI Sequence Viewer  
  NP_001381298 (Get FASTA)   NCBI Sequence Viewer  
  XP_006237400 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM01922 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001100089   ⟸   NM_001106619
- UniProtKB: D3ZVQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237400   ⟸   XM_006237338
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000020785   ⟸   ENSRNOT00000020785
RefSeq Acc Id: ENSRNOP00000078694   ⟸   ENSRNOT00000109840
Protein Domains
UBA   UBP-type   USP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZVQ0-F1-model_v2 AlphaFold D3ZVQ0 1-858 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693391
Promoter ID:EPDNEW_R3916
Type:initiation region
Name:Usp5_1
Description:ubiquitin specific peptidase 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04157,347,773 - 157,347,833EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308438 AgrOrtholog
BioCyc Gene G2FUF-43065 BioCyc
Ensembl Genes ENSRNOG00000015409 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000020785 ENTREZGENE
  ENSRNOP00000020785.4 UniProtKB/TrEMBL
  ENSRNOP00000078694 ENTREZGENE
  ENSRNOP00000078694.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020785 ENTREZGENE
  ENSRNOT00000020785.6 UniProtKB/TrEMBL
  ENSRNOT00000109840 ENTREZGENE
  ENSRNOT00000109840.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Papain_like_cys_pep_sf UniProtKB/TrEMBL
  Pept_C19ubi-hydrolase_C_CS UniProtKB/TrEMBL
  Peptidase_C19 UniProtKB/TrEMBL
  UBA-like UniProtKB/TrEMBL
  UBA/transl_elong_EF1B_N_euk UniProtKB/TrEMBL
  Ubiquitinyl_hydrolase UniProtKB/TrEMBL
  UBP13_Znf-UBP_var UniProtKB/TrEMBL
  UBP5_UBA1 UniProtKB/TrEMBL
  UCH/PAN2 UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
  Znf_UBP UniProtKB/TrEMBL
KEGG Report rno:297593 UniProtKB/TrEMBL
NCBI Gene 297593 ENTREZGENE
Pfam UBA UniProtKB/TrEMBL
  UCH UniProtKB/TrEMBL
  zf-UBP UniProtKB/TrEMBL
  zf-UBP_var UniProtKB/TrEMBL
PhenoGen Usp5 PhenoGen
PIRSF UBP UniProtKB/TrEMBL
PROSITE UBA UniProtKB/TrEMBL
  UCH_2_1 UniProtKB/TrEMBL
  UCH_2_2 UniProtKB/TrEMBL
  UCH_2_3 UniProtKB/TrEMBL
  ZF_UBP UniProtKB/TrEMBL
SMART UBA UniProtKB/TrEMBL
  ZnF_UBP UniProtKB/TrEMBL
Superfamily-SCOP SSF54001 UniProtKB/TrEMBL
  UBA_like UniProtKB/TrEMBL
UniProt A0A8I5ZLA4_RAT UniProtKB/TrEMBL
  D3ZVQ0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Usp5  ubiquitin specific peptidase 5  LOC100911959  ubiquitin carboxyl-terminal hydrolase 5-like  Data Merged 737654 PROVISIONAL
2016-04-13 Usp5  ubiquitin specific peptidase 5  Usp5  ubiquitin specific peptidase 5 (isopeptidase T)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911959  ubiquitin carboxyl-terminal hydrolase 5-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-03-04 Usp5  ubiquitin specific peptidase 5 (isopeptidase T)  Usp5_predicted  ubiquitin specific protease 5 (isopeptidase T) (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Usp5_predicted  ubiquitin specific protease 5 (isopeptidase T) (predicted)      Symbol and Name status set to approved 70820 APPROVED