(2,4,5-trichlorophenoxy)acetic acid increases expression ISO RGD:11094 6480464 2,4,5-Trichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 (6aR,9R)-N-[(2S)-1-hydroxybutan-2-yl]-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide decreases activity ISO RGD:736946 6480464 Methysergide results in decreased activity of ABCB4 protein CTD PMID:28437613 (RS)-coclaurine multiple interactions ISO RGD:11094 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCB4 mRNA CTD PMID:28843594 (RS)-norcoclaurine multiple interactions ISO RGD:11094 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCB4 mRNA CTD PMID:28843594 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE decreases expression EXP 6480464 Topotecan results in decreased expression of ABCB4 mRNA CTD PMID:25729387 (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ABCB4 mRNA CTD PMID:25729387 (S)-coclaurine multiple interactions ISO RGD:11094 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCB4 mRNA CTD PMID:28843594 1,9-dideoxyforskolin decreases activity EXP 6480464 1,9-dideoxyforskolin results in decreased activity of ABCB4 protein CTD PMID:12202523 1-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-2-(4-chlorophenoxy)ethanone decreases activity ISO RGD:736946 6480464 fipexide results in decreased activity of ABCB4 protein CTD PMID:28437613 1-naphthyl isothiocyanate multiple interactions ISO RGD:11094 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA]; more ... CTD PMID:15913567 more ... 1-naphthyl isothiocyanate decreases expression EXP 6480464 1-Naphthylisothiocyanate results in decreased expression of ABCB4 mRNA CTD PMID:27765674 1-naphthyl isothiocyanate increases expression ISO RGD:11094 6480464 1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA; more ... CTD PMID:15913567 more ... 1-naphthyl isothiocyanate multiple interactions ISO RGD:736946 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 1-naphthyl isothiocyanate increases expression EXP 6480464 1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA CTD PMID:14623915 PMID:27765674 1-phenyl-1-cyclopentanecarboxylic acid 2-[2-(diethylamino)ethoxy]ethyl ester decreases activity ISO RGD:736946 6480464 carbetapentane results in decreased activity of ABCB4 protein CTD PMID:28437613 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of ABCB4 mRNA CTD PMID:16940010 PMID:27765674 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of ABCB4 mRNA CTD PMID:27765674 17alpha-ethynylestradiol multiple interactions ISO RGD:736946 6480464 [Ethinyl Estradiol co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of ABCB4 mRNA CTD PMID:15212814 17beta-estradiol decreases expression ISO RGD:736946 6480464 Estradiol results in decreased expression of ABCB4 mRNA CTD PMID:20106945 17beta-estradiol 17-glucosiduronic acid affects export ISO RGD:11094 6480464 ABCB4 protein affects the export of estradiol-17 beta-glucuronide CTD PMID:11302927 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2,2',4,4'-tetrabromodiphenyl ether results in increased expression of ABCB4 mRNA CTD PMID:27291303 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ABCB4 mRNA CTD PMID:21724226 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:11094 6480464 [Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of ABCB4 mRNA CTD PMID:25975270 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:11094 6480464 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of ABCB4 mRNA CTD PMID:24713691 2,3,7,8-Tetrachlorodibenzofuran decreases expression EXP 6480464 2,3,7,8-tetrachlorodibenzofuran results in decreased expression of ABCB4 mRNA CTD PMID:21724226 2,4-D increases expression ISO RGD:11094 6480464 2,4-Dichlorophenoxyacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:9210621 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile decreases activity ISO RGD:736946 6480464 Verapamil results in decreased activity of ABCB4 protein CTD PMID:28437613 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile decreases expression ISO RGD:736946 6480464 Verapamil results in decreased expression of ABCB4 mRNA CTD PMID:28552422 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile decreases activity EXP 6480464 Verapamil results in decreased activity of ABCB4 protein CTD PMID:12202523 3,3',5-triiodo-L-thyronine decreases activity ISO RGD:736946 6480464 Triiodothyronine results in decreased activity of ABCB4 protein CTD PMID:28437613 3,5-diethoxycarbonyl-1,4-dihydrocollidine increases expression ISO RGD:11094 6480464 3,5-diethoxycarbonyl-1,4-dihydrocollidine results in increased expression of ABCB4 mRNA CTD PMID:8707270 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:736946 6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] CTD PMID:11331069 3-methylcholanthrene multiple interactions ISO RGD:11094 6480464 [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ABCB4 mRNA CTD PMID:25926378 3H-1,2-dithiole-3-thione decreases expression EXP 6480464 1,2-dithiol-3-thione results in decreased expression of ABCB4 mRNA CTD PMID:19162173 4,4'-diaminodiphenylmethane increases expression ISO RGD:11094 6480464 4,4'-diaminodiphenylmethane results in increased expression of ABCB4 mRNA CTD PMID:18648102 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester decreases activity ISO RGD:736946 6480464 Loratadine results in decreased activity of ABCB4 protein CTD PMID:28437613 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole decreases expression ISO RGD:736946 6480464 Omeprazole results in decreased expression of ABCB4 mRNA CTD PMID:12040753 adefovir multiple interactions EXP 6480464 Calcitriol promotes the reaction [ABCB4 protein affects the transport of adefovir] CTD PMID:21240898 PMID:21341280 adefovir affects transport EXP 6480464 ABCB4 protein affects the transport of adefovir CTD PMID:21240898 PMID:21341280 aflatoxin B1 affects expression ISO RGD:736946 6480464 Aflatoxin B1 affects the expression of ABCB4 protein CTD PMID:20106945 aflatoxin B1 decreases methylation ISO RGD:736946 6480464 Aflatoxin B1 results in decreased methylation of ABCB4 gene CTD PMID:27153756 aflatoxin B1 multiple interactions ISO RGD:736946 6480464 [Aflatoxin B1 co-treated with finrozole] results in increased expression of ABCB4 mRNA CTD PMID:23402939 all-trans-retinoic acid increases expression ISO RGD:736946 6480464 Tretinoin results in increased expression of ABCB4 mRNA CTD PMID:21934132 alpha-hexachlorocyclohexane increases expression EXP 6480464 alpha-hexachlorocyclohexane results in increased expression of ABCB4 mRNA CTD PMID:16940010 amiodarone increases expression ISO RGD:11094 6480464 Amiodarone results in increased expression of ABCB4 mRNA CTD PMID:24489787 amiodarone decreases expression EXP 6480464 Amiodarone results in decreased expression of ABCB4 mRNA CTD PMID:27765674 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ABCB4 mRNA CTD PMID:16483693 arsenite(3-) affects expression ISO RGD:736946 6480464 arsenite affects the expression of ABCB4 mRNA CTD PMID:22959463 atorvastatin calcium increases expression ISO RGD:11094 6480464 Atorvastatin Calcium results in increased expression of ABCB4 mRNA; more ... CTD PMID:15986414 PMID:25278499 azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of ABCB4 mRNA CTD PMID:27765674 beclomethasone increases expression ISO RGD:736946 6480464 Beclomethasone results in increased expression of ABCB4 mRNA CTD PMID:15370884 benzarone decreases activity ISO RGD:736946 6480464 benzarone results in decreased activity of ABCB4 protein CTD PMID:28437613 benzatropine decreases activity ISO RGD:736946 6480464 Benztropine results in decreased activity of ABCB4 protein CTD PMID:28437613 benzbromarone decreases activity ISO RGD:736946 6480464 Benzbromarone results in decreased activity of ABCB4 protein CTD PMID:28437613 benziodarone decreases activity ISO RGD:736946 6480464 benziodarone results in decreased activity of ABCB4 protein CTD PMID:28437613 benzo[a]pyrene increases expression ISO RGD:736946 6480464 Benzo(a)pyrene results in increased expression of ABCB4 mRNA CTD PMID:20064835 benzo[b]fluoranthene increases expression ISO RGD:11094 6480464 benzo(b)fluoranthene results in increased expression of ABCB4 mRNA CTD PMID:26377693 bezafibrate affects localization ISO RGD:736946 6480464 Bezafibrate affects the localization of ABCB4 protein CTD PMID:15258199 bezafibrate increases expression ISO RGD:736946 6480464 Bezafibrate results in increased expression of ABCB4 mRNA; more ... CTD PMID:15258199 PMID:15588777 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of ABCB4 mRNA CTD PMID:15242490 bezafibrate increases expression ISO RGD:11094 6480464 Bezafibrate results in increased expression of ABCB4 mRNA CTD PMID:15258199 PMID:17118139 bezafibrate multiple interactions ISO RGD:736946 6480464 [Bezafibrate co-treated with Chenodeoxycholic Acid] results in increased expression of ABCB4 mRNA; more ... CTD PMID:15258199 PMID:15588777 bicalutamide decreases activity ISO RGD:736946 6480464 bicalutamide results in decreased activity of ABCB4 protein CTD PMID:28437613 biperiden decreases activity ISO RGD:736946 6480464 Biperiden results in decreased activity of ABCB4 protein CTD PMID:28437613 bis(2-ethylhexyl) phthalate increases expression ISO RGD:11094 6480464 Diethylhexyl Phthalate results in increased expression of ABCB4 mRNA CTD PMID:9210621 bisphenol A decreases expression ISO RGD:11094 6480464 bisphenol A results in decreased expression of ABCB4 mRNA CTD PMID:26063408 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ABCB4 mRNA CTD PMID:25181051 bromosulfophthalein affects transport EXP 6480464 ABCB4 protein affects the transport of Sulfobromophthalein CTD PMID:15304119 brompheniramine decreases activity ISO RGD:736946 6480464 Brompheniramine results in decreased activity of ABCB4 protein CTD PMID:28437613 buta-1,3-diene decreases expression ISO RGD:11094 6480464 1,3-butadiene results in decreased expression of ABCB4 mRNA CTD PMID:29038090 cadmium dichloride increases methylation EXP 6480464 Cadmium Chloride results in increased methylation of ABCB4 promoter CTD PMID:22457795 caffeine multiple interactions ISO RGD:11094 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCB4 mRNA CTD PMID:28843594 calcitriol multiple interactions EXP 6480464 Calcitriol promotes the reaction [ABCB4 protein affects the transport of adefovir] CTD PMID:21240898 PMID:21341280 carbon nanotube multiple interactions ISO RGD:11094 6480464 [Methylcholanthrene co-treated with Nanotubes, Carbon] results in decreased expression of ABCB4 mRNA CTD PMID:25926378 carboplatin decreases expression EXP 6480464 Carboplatin results in decreased expression of ABCB4 mRNA CTD PMID:18172885 chenodeoxycholic acid multiple interactions ISO RGD:736946 6480464 [[Chenodeoxycholic Acid binds to and results in increased activity of NR1H4 protein] which binds to ABCB4 promoter] which results in increased expression of ABCB4 mRNA; more ... CTD PMID:14527955 PMID:15588777 chenodeoxycholic acid increases expression ISO RGD:11094 6480464 Chenodeoxycholic Acid results in increased expression of ABCB4 mRNA CTD PMID:25582706 chenodeoxycholic acid increases expression ISO RGD:736946 6480464 Chenodeoxycholic Acid results in increased expression of ABCB4 mRNA CTD PMID:14527955 more ... chlorphenamine decreases activity ISO RGD:736946 6480464 Chlorpheniramine results in decreased activity of ABCB4 protein CTD PMID:28437613 chlorpromazine multiple interactions ISO RGD:736946 6480464 [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 cholesterol affects export ISO RGD:11094 6480464 ABCB4 protein affects the export of Cholesterol CTD PMID:15019087 cholic acid affects secretion ISO RGD:11094 6480464 ABCB4 affects the secretion of Cholic Acid CTD PMID:12967592 cholic acid increases expression ISO RGD:11094 6480464 Cholic Acid results in increased expression of ABCB4 mRNA CTD PMID:22961653 PMID:25582706 cholic acid multiple interactions ISO RGD:11094 6480464 epiallopregnanolone sulfate inhibits the reaction [Cholic Acid results in increased expression of ABCB4 mRNA] CTD PMID:22961653 chromium(6+) affects expression ISO RGD:11094 6480464 chromium hexavalent ion affects the expression of ABCB4 mRNA CTD PMID:28472532 ciprofibrate increases expression ISO RGD:11094 6480464 ciprofibrate results in increased expression of ABCB4 mRNA; more ... CTD PMID:12381268 clemastine decreases activity ISO RGD:736946 6480464 Clemastine results in decreased activity of ABCB4 protein CTD PMID:28437613 clofibrate multiple interactions ISO RGD:11094 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ABCB4 mRNA; more ... CTD PMID:17585979 clofibrate increases expression ISO RGD:11094 6480464 Clofibrate results in increased expression of ABCB4 mRNA CTD PMID:17585979 PMID:23811191 clofibric acid increases activity ISO RGD:11094 6480464 Clofibric Acid results in increased activity of ABCB4 protein CTD PMID:12381268 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCB4 mRNA CTD PMID:17602206 clofibric acid increases expression ISO RGD:11094 6480464 Clofibric Acid results in increased expression of ABCB4 mRNA CTD PMID:12512040 Colforsin dapropate hydrochloride multiple interactions ISO RGD:736946 6480464 Colforsin inhibits the reaction [Doxorubicin results in increased expression of ABCB4 mRNA]; more ... CTD PMID:12926078 Colforsin dapropate hydrochloride decreases expression ISO RGD:736946 6480464 Colforsin results in decreased expression of ABCB4 mRNA CTD PMID:12926078 copper(II) sulfate decreases expression ISO RGD:736946 6480464 Copper Sulfate results in decreased expression of ABCB4 mRNA CTD PMID:19549813 cycloheximide multiple interactions ISO RGD:736946 6480464 Cycloheximide inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA] CTD PMID:11331069 cyclosporin A decreases expression ISO RGD:11094 6480464 Cyclosporine results in decreased expression of ABCB4 mRNA CTD PMID:23830897 cyclosporin A increases expression ISO RGD:736946 6480464 Cyclosporine results in increased expression of ABCB4 mRNA CTD PMID:27989131 cyclosporin A decreases expression ISO RGD:736946 6480464 Cyclosporine results in decreased expression of ABCB4 mRNA CTD PMID:20106945 more ... deoxycholic acid affects expression ISO RGD:11094 6480464 Deoxycholic Acid affects the expression of ABCB4 mRNA CTD PMID:21914718 deoxycholic acid increases expression ISO RGD:11094 6480464 Deoxycholic Acid results in increased expression of ABCB4 mRNA CTD PMID:25582706 deoxycholic acid multiple interactions ISO RGD:11094 6480464 SLCO1A1 protein affects the susceptibility to [Deoxycholic Acid affects the expression of ABCB4 mRNA] CTD PMID:21914718 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of ABCB4 mRNA CTD PMID:12429353 PMID:19118567 diarsenic trioxide increases expression ISO RGD:736946 6480464 arsenic trioxide results in increased expression of ABCB4 mRNA CTD PMID:27829220 dibenz[a,h]anthracene increases expression ISO RGD:11094 6480464 1,2,5,6-dibenzanthracene results in increased expression of ABCB4 mRNA CTD PMID:26377693 dichloroacetic acid increases expression ISO RGD:11094 6480464 Dichloroacetic Acid results in increased expression of ABCB4 mRNA CTD PMID:28962523 diclofenac decreases expression ISO RGD:736946 6480464 Diclofenac results in decreased expression of ABCB4 mRNA CTD PMID:19022234 diclofenac decreases activity ISO RGD:736946 6480464 Diclofenac results in decreased activity of ABCB4 protein CTD PMID:28437613 dihydroergotamine decreases activity ISO RGD:736946 6480464 Dihydroergotamine results in decreased activity of ABCB4 protein CTD PMID:28437613 dorsomorphin multiple interactions ISO RGD:736946 6480464 [NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCB4 mRNA CTD PMID:27188386 doxorubicin decreases response to substance ISO RGD:736946 6480464 ABCB4 protein results in decreased susceptibility to Doxorubicin CTD PMID:11313874 doxorubicin multiple interactions ISO RGD:736946 6480464 Colforsin inhibits the reaction [Doxorubicin results in increased expression of ABCB4 mRNA] CTD PMID:12926078 doxorubicin increases expression ISO RGD:736946 6480464 Doxorubicin results in increased expression of ABCB4 mRNA CTD PMID:16579640 doxycycline decreases expression EXP 6480464 Doxycycline results in decreased expression of ABCB4 mRNA CTD PMID:27765674 doxylamine decreases activity ISO RGD:736946 6480464 Doxylamine results in decreased activity of ABCB4 protein CTD PMID:28437613 ebrotidine decreases activity ISO RGD:736946 6480464 ebrotidine results in decreased activity of ABCB4 protein CTD PMID:28437613 emodin decreases expression EXP 6480464 Emodin results in decreased expression of ABCB4 mRNA CTD PMID:28161596 entinostat increases expression ISO RGD:736946 6480464 entinostat results in increased expression of ABCB4 mRNA CTD PMID:27188386 esmolol decreases activity ISO RGD:736946 6480464 esmolol results in decreased activity of ABCB4 protein CTD PMID:28437613 fenofibrate increases expression ISO RGD:11094 6480464 Fenofibrate results in increased expression of ABCB4 mRNA CTD PMID:17118139 fenofibrate increases expression ISO RGD:736946 6480464 Fenofibrate results in increased expression of ABCB4 mRNA CTD PMID:19118567 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of ABCB4 mRNA CTD PMID:24136188 PMID:24793618 flutamide decreases activity ISO RGD:736946 6480464 Flutamide results in decreased activity of ABCB4 protein CTD PMID:28437613 fluvoxamine decreases activity ISO RGD:736946 6480464 Fluvoxamine results in decreased activity of ABCB4 protein CTD PMID:28437613 fumonisin B1 increases expression ISO RGD:11094 6480464 fumonisin B1 results in increased expression of ABCB4 mRNA CTD PMID:16221962 furan increases expression EXP 6480464 furan results in increased expression of ABCB4 mRNA CTD PMID:15120968 genistein decreases expression EXP 6480464 Genistein results in decreased expression of ABCB4 mRNA CTD PMID:19364372 gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of ABCB4 mRNA CTD PMID:22061828 glutathione affects export ISO RGD:11094 6480464 ABCB4 protein affects the export of Glutathione CTD PMID:11302927 glyburide increases expression EXP 6480464 Glyburide results in increased expression of ABCB4 mRNA CTD PMID:27765674 glycyrrhetinate multiple interactions ISO RGD:11094 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA] CTD PMID:28549656 glycyrrhetinic acid multiple interactions ISO RGD:11094 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA] CTD PMID:28549656 gold atom multiple interactions ISO RGD:736946 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA CTD PMID:28433809 gold(0) multiple interactions ISO RGD:736946 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA CTD PMID:28433809 gold(1+) multiple interactions ISO RGD:736946 6480464 [Polyethyleneimine binds to Gold] which results in decreased expression of ABCB4 mRNA CTD PMID:28433809 griseofulvin increases expression ISO RGD:11094 6480464 Griseofulvin results in increased expression of ABCB4 mRNA CTD PMID:8707270 guanethidine decreases activity ISO RGD:736946 6480464 Guanethidine results in decreased activity of ABCB4 protein CTD PMID:28437613 guggulsterone multiple interactions ISO RGD:11094 6480464 pregna-4,17-diene-3,16-dione inhibits the reaction [alisol B 23-acetate promotes the reaction [1-Naphthylisothiocyanate results in increased expression of ABCB4 mRNA]] CTD PMID:25655198 GW 4064 multiple interactions ISO RGD:736946 6480464 [[GW 4064 binds to and results in increased activity of NR1H4 protein] which binds to ABCB4 promoter] which results in increased expression of ABCB4 mRNA CTD PMID:14527955 GW 4064 increases expression ISO RGD:11094 6480464 GW 4064 results in increased expression of ABCB4 mRNA CTD PMID:27609522 GW 4064 increases expression EXP 6480464 GW 4064 results in increased expression of ABCB4 mRNA CTD PMID:15644430 GW 4064 increases expression ISO RGD:736946 6480464 GW 4064 results in increased expression of ABCB4 mRNA CTD PMID:14527955 PMID:14623915 herbicide increases expression ISO RGD:11094 6480464 Herbicides results in increased expression of ABCB4 mRNA CTD PMID:9210621 hydroxyzine decreases activity ISO RGD:736946 6480464 Hydroxyzine results in decreased activity of ABCB4 protein CTD PMID:28437613 indocyanine green affects export ISO RGD:11094 6480464 ABCB4 protein affects the export of Indocyanine Green CTD PMID:11302927 isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of ABCB4 mRNA CTD PMID:24286936 isoprenaline decreases expression ISO RGD:736946 6480464 Isoproterenol results in decreased expression of ABCB4 mRNA CTD PMID:24286936 ketoconazole decreases activity ISO RGD:736946 6480464 Ketoconazole results in decreased activity of ABCB4 protein CTD PMID:28437613 labetalol decreases activity ISO RGD:736946 6480464 Labetalol results in decreased activity of ABCB4 protein CTD PMID:28437613 lapatinib decreases activity ISO RGD:736946 6480464 lapatinib results in decreased activity of ABCB4 protein CTD PMID:28437613 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of ABCB4 mRNA CTD PMID:24136188 leflunomide decreases activity ISO RGD:736946 6480464 leflunomide results in decreased activity of ABCB4 protein CTD PMID:28437613 lipopolysaccharide affects expression ISO RGD:11094 6480464 Lipopolysaccharides affects the expression of ABCB4 protein CTD PMID:15778272 lipopolysaccharide decreases expression ISO RGD:11094 6480464 Lipopolysaccharides results in decreased expression of ABCB4 mRNA CTD PMID:15778272 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of ABCB4 protein CTD PMID:12795754 lithocholic acid increases expression ISO RGD:11094 6480464 Lithocholic Acid results in increased expression of ABCB4 mRNA CTD PMID:20359477 PMID:25582706 methapyrilene increases expression EXP 6480464 Methapyrilene results in increased expression of ABCB4 mRNA CTD PMID:15120968 PMID:28935588 methapyrilene decreases expression ISO RGD:736946 6480464 Methapyrilene results in decreased expression of ABCB4 mRNA CTD PMID:28935588 methotrexate increases expression ISO RGD:736946 6480464 Methotrexate results in increased expression of ABCB4 mRNA CTD PMID:24449571 methotrexate decreases activity ISO RGD:736946 6480464 Methotrexate results in decreased activity of ABCB4 protein CTD PMID:28437613 methoxsalen decreases expression ISO RGD:736946 6480464 Methoxsalen results in decreased expression of ABCB4 mRNA CTD PMID:28552422 methoxsalen decreases expression EXP 6480464 Methoxsalen results in decreased expression of ABCB4 mRNA; more ... CTD PMID:28552422 methyltestosterone multiple interactions ISO RGD:736946 6480464 [Methyltestosterone co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 methysergide decreases activity ISO RGD:736946 6480464 Methysergide results in decreased activity of ABCB4 protein CTD PMID:28437613 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO RGD:736946 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Colforsin results in decreased expression of ABCB4 mRNA] CTD PMID:12926078 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCB4 mRNA CTD PMID:17602206 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of ABCB4 mRNA CTD PMID:24136188 nefazodone decreases activity ISO RGD:736946 6480464 nefazodone results in decreased activity of ABCB4 protein CTD PMID:28437613 nitrofurantoin decreases activity ISO RGD:736946 6480464 Nitrofurantoin results in decreased activity of ABCB4 protein CTD PMID:28437613 nomifensine decreases activity ISO RGD:736946 6480464 Nomifensine results in decreased activity of ABCB4 protein CTD PMID:28437613 nortriptyline decreases activity ISO RGD:736946 6480464 Nortriptyline results in decreased activity of ABCB4 protein CTD PMID:28437613 obeticholic acid multiple interactions EXP 6480464 obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB4 mRNA] CTD PMID:27255380 obeticholic acid increases expression ISO RGD:736946 6480464 obeticholic acid results in increased expression of ABCB4 mRNA CTD PMID:27939613 obeticholic acid increases expression EXP 6480464 obeticholic acid results in increased expression of ABCB4 mRNA CTD PMID:15644430 omeprazole decreases expression ISO RGD:736946 6480464 Omeprazole results in decreased expression of ABCB4 mRNA CTD PMID:12040753 oxaliplatin decreases expression EXP 6480464 oxaliplatin results in decreased expression of ABCB4 mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ABCB4 mRNA CTD PMID:25729387 oxybutynin decreases activity ISO RGD:736946 6480464 oxybutynin results in decreased activity of ABCB4 protein CTD PMID:28437613 oxycodone increases expression EXP 6480464 Oxycodone results in increased expression of ABCB4 mRNA CTD PMID:23439660 paclitaxel decreases response to substance ISO RGD:736946 6480464 ABCB4 protein results in decreased susceptibility to Paclitaxel CTD PMID:17697605 paliperidone palmitate decreases activity ISO RGD:736946 6480464 Paliperidone Palmitate results in decreased activity of ABCB4 protein CTD PMID:28437613 paracetamol multiple interactions ISO RGD:11094 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ABCB4 mRNA; more ... CTD PMID:17585979 paracetamol decreases expression ISO RGD:736946 6480464 Acetaminophen results in decreased expression of ABCB4 mRNA CTD PMID:21420995 PMID:29067470 pazopanib decreases activity ISO RGD:736946 6480464 pazopanib results in decreased activity of ABCB4 protein CTD PMID:28437613 penbutolol decreases activity ISO RGD:736946 6480464 Penbutolol results in decreased activity of ABCB4 protein CTD PMID:28437613 perfluoroheptanoic acid increases expression ISO RGD:736946 6480464 perfluoro-n-heptanoic acid results in increased expression of ABCB4 mRNA CTD PMID:23567314 perfluorohexanesulfonic acid increases expression ISO RGD:736946 6480464 perfluorohexanesulfonic acid results in increased expression of ABCB4 mRNA CTD PMID:23567314 perfluorononanoic acid increases expression ISO RGD:736946 6480464 perfluoro-n-nonanoic acid results in increased expression of ABCB4 mRNA CTD PMID:23567314 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of ABCB4 mRNA CTD PMID:19162173 perfluorooctane-1-sulfonic acid increases expression ISO RGD:736946 6480464 perfluorooctane sulfonic acid results in increased expression of ABCB4 mRNA CTD PMID:23567314 perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of ABCB4 mRNA CTD PMID:19162173 perhexiline decreases activity ISO RGD:736946 6480464 Perhexiline results in decreased activity of ABCB4 protein CTD PMID:28437613 perhexiline decreases expression EXP 6480464 Perhexiline results in decreased expression of ABCB4 mRNA CTD PMID:27765674 phenazopyridine decreases activity ISO RGD:736946 6480464 Phenazopyridine results in decreased activity of ABCB4 protein CTD PMID:28437613 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of ABCB4 mRNA CTD PMID:19162173 Phenoxybenzamine decreases activity ISO RGD:736946 6480464 Phenoxybenzamine results in decreased activity of ABCB4 protein CTD PMID:28437613 phentolamine decreases activity ISO RGD:736946 6480464 Phentolamine results in decreased activity of ABCB4 protein CTD PMID:28437613 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:736946 6480464 bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA]; more ... CTD PMID:11331069 phorbol 13-acetate 12-myristate decreases expression ISO RGD:736946 6480464 Tetradecanoylphorbol Acetate results in decreased expression of ABCB4 mRNA CTD PMID:11331069 phosphatidylcholine affects export ISO RGD:736946 6480464 ABCB4 protein affects the export of Phosphatidylcholines CTD PMID:15696852 phosphatidylcholine affects transport ISO RGD:11094 6480464 ABCB4 protein affects the transport of Phosphatidylcholines CTD PMID:11745043 physcion decreases expression EXP 6480464 physcione results in decreased expression of ABCB4 mRNA CTD PMID:28161596 pirinixic acid increases expression ISO RGD:11094 6480464 pirinixic acid results in increased expression of ABCB4 mRNA CTD PMID:12381268 PMID:18301758 pravastatin increases expression EXP 6480464 Pravastatin results in increased expression of ABCB4 mRNA CTD PMID:15242490 pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of ABCB4 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:11094 6480464 Pregnenolone Carbonitrile results in decreased expression of ABCB4 mRNA CTD PMID:28903501 primaquine decreases activity ISO RGD:736946 6480464 Primaquine results in decreased activity of ABCB4 protein CTD PMID:28437613 procyclidine decreases activity ISO RGD:736946 6480464 Procyclidine results in decreased activity of ABCB4 protein CTD PMID:28437613 procymidone increases expression EXP 6480464 procymidone results in increased expression of ABCB4 mRNA CTD PMID:15686871 propiconazole decreases expression ISO RGD:11094 6480464 propiconazole results in decreased expression of ABCB4 mRNA CTD PMID:21278054 protriptyline decreases activity ISO RGD:736946 6480464 Protriptyline results in decreased activity of ABCB4 protein CTD PMID:28437613 pyrazinecarboxamide decreases expression EXP 6480464 Pyrazinamide results in decreased expression of ABCB4 mRNA; more ... CTD PMID:27255380 pyrazinecarboxamide multiple interactions EXP 6480464 obeticholic acid inhibits the reaction [Pyrazinamide results in decreased expression of ABCB4 mRNA] CTD PMID:27255380 quercetin decreases expression ISO RGD:736946 6480464 Quercetin results in decreased expression of ABCB4 mRNA CTD PMID:21632981 rifampicin increases expression ISO RGD:736946 6480464 Rifampin results in increased expression of ABCB4 mRNA CTD PMID:27199754 ritonavir decreases activity ISO RGD:736946 6480464 Ritonavir results in decreased activity of ABCB4 protein CTD PMID:28437613 ritonavir decreases expression ISO RGD:736946 6480464 Ritonavir results in decreased expression of ABCB4 CTD PMID:26626330 SB 431542 multiple interactions ISO RGD:736946 6480464 [NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCB4 mRNA CTD PMID:27188386 simvastatin increases expression ISO RGD:11094 6480464 Simvastatin results in increased expression of ABCB4 mRNA CTD PMID:21241519 simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of ABCB4 mRNA CTD PMID:27765674 sodium dichromate increases expression EXP 6480464 sodium bichromate results in increased expression of ABCB4 mRNA CTD PMID:12325037 Soman increases expression EXP 6480464 Soman results in increased expression of ABCB4 mRNA CTD PMID:19281266 streptozocin increases expression EXP 6480464 Streptozocin results in increased expression of ABCB4 mRNA; more ... CTD PMID:12055592 tacrine decreases activity ISO RGD:736946 6480464 Tacrine results in decreased activity of ABCB4 protein CTD PMID:28437613 tamoxifen decreases activity EXP 6480464 Tamoxifen results in decreased activity of ABCB4 protein CTD PMID:12202523 tamoxifen decreases activity ISO RGD:736946 6480464 Tamoxifen results in decreased activity of ABCB4 protein CTD PMID:28437613 tamsulosin decreases activity ISO RGD:736946 6480464 tamsulosin results in decreased activity of ABCB4 protein CTD PMID:28437613 tasosartan decreases activity ISO RGD:736946 6480464 tasosartan results in decreased activity of ABCB4 protein CTD PMID:28437613 taurocholic acid increases expression EXP 6480464 Taurocholic Acid results in increased expression of ABCB4 protein CTD PMID:11113123 Technetium tc 99m sestamibi affects export ISO RGD:11094 6480464 ABCB4 protein affects the export of Technetium Tc 99m Sestamibi CTD PMID:12536246 tenofovir disoproxil fumarate decreases activity ISO RGD:736946 6480464 Tenofovir results in decreased activity of ABCB4 protein CTD PMID:28437613 tetracycline decreases expression ISO RGD:11094 6480464 Tetracycline results in decreased expression of ABCB4 mRNA CTD PMID:24489787 tetracycline decreases expression EXP 6480464 Tetracycline results in decreased expression of ABCB4 mRNA CTD PMID:27765674 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of ABCB4 mRNA CTD PMID:26222700 tipranavir decreases activity ISO RGD:736946 6480464 tipranavir results in decreased activity of ABCB4 protein CTD PMID:28437613 titanium dioxide decreases expression ISO RGD:11094 6480464 titanium dioxide results in decreased expression of ABCB4 mRNA CTD PMID:23409001 tolterodine tartrate decreases activity ISO RGD:736946 6480464 Tolterodine Tartrate results in decreased activity of ABCB4 protein CTD PMID:28437613 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ABCB4 mRNA CTD PMID:25729387 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of ABCB4 mRNA CTD PMID:25729387 triadimefon decreases expression ISO RGD:11094 6480464 triadimefon results in decreased expression of ABCB4 mRNA CTD PMID:16730040 troglitazone increases expression ISO RGD:736946 6480464 troglitazone results in increased expression of ABCB4 mRNA CTD PMID:19022234 troglitazone decreases activity ISO RGD:736946 6480464 troglitazone results in decreased activity of ABCB4 protein CTD PMID:28437613 troglitazone increases expression EXP 6480464 troglitazone results in increased expression of ABCB4 mRNA CTD PMID:19022234 ursodeoxycholic acid increases expression ISO RGD:11094 6480464 Ursodeoxycholic Acid results in increased expression of ABCB4 mRNA CTD PMID:25582706 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of ABCB4 mRNA CTD PMID:24136188 valproic acid decreases methylation ISO RGD:736946 6480464 Valproic Acid results in decreased methylation of ABCB4 gene CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of ABCB4 mRNA CTD PMID:27765674 valproic acid increases expression ISO RGD:736946 6480464 Valproic Acid results in increased expression of ABCB4 mRNA CTD PMID:23179753 more ... valproic acid multiple interactions ISO RGD:736946 6480464 [NOG protein co-treated with Valproic Acid co-treated with (6-(4-(2-piperidin-1-ylethoxy)phenyl))-3-pyridin-4-ylpyrazolo(1,5-a)pyrimidine co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ABCB4 mRNA CTD PMID:27188386 valproic acid affects expression ISO RGD:736946 6480464 Valproic Acid affects the expression of ABCB4 mRNA CTD PMID:25979313 verapamil decreases activity EXP 6480464 Verapamil results in decreased activity of ABCB4 protein CTD PMID:12202523 verapamil decreases expression ISO RGD:736946 6480464 Verapamil results in decreased expression of ABCB4 mRNA CTD PMID:28552422 verapamil decreases activity ISO RGD:736946 6480464 Verapamil results in decreased activity of ABCB4 protein CTD PMID:28437613 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of ABCB4 mRNA CTD PMID:15686871 vincristine multiple interactions ISO RGD:736946 6480464 [Vincristine results in decreased susceptibility to Vincristine] which affects the expression of ABCB4 mRNA CTD PMID:19944135 vorinostat increases expression ISO RGD:736946 6480464 vorinostat results in increased expression of ABCB4 mRNA CTD PMID:27188386 yohimbine multiple interactions ISO RGD:11094 6480464 [Caffeine co-treated with coclaurine co-treated with aegeline co-treated with higenamine co-treated with Yohimbine co-treated with Hydrolyzable Tannins] results in increased expression of ABCB4 mRNA CTD PMID:28843594 zafirlukast decreases activity ISO RGD:736946 6480464 zafirlukast results in decreased activity of ABCB4 protein CTD PMID:28437613 zimeldine decreases activity ISO RGD:736946 6480464 Zimeldine results in decreased activity of ABCB4 protein CTD PMID:28437613
Gene-Chemical Interaction Annotations
