Fgf12 (fibroblast growth factor 12) - Rat Genome Database

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Gene: Fgf12 (fibroblast growth factor 12) Rattus norvegicus
Analyze
Symbol: Fgf12
Name: fibroblast growth factor 12
RGD ID: 620163
Description: Exhibits ion channel binding activity and sodium channel regulator activity. Involved in negative regulation of cation channel activity; regulation of membrane depolarization; and regulation of sodium ion transmembrane transporter activity. Predicted to localize to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 47. Orthologous to human FGF12 (fibroblast growth factor 12); PARTICIPATES IN melanoma pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: FGF-12; Fgf1a; FHF-1; Fhf1; Fhf1b; fibroblast growth factor 1a; fibroblast growth factor homologous factor 1; fibroblast growth factor homologous factor 1b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21171,997,049 - 72,564,965 (+)NCBI
Rnor_6.0 Ensembl1175,905,443 - 76,168,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01175,606,360 - 76,171,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01178,647,628 - 79,212,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,208,696 - 74,481,037 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11174,266,284 - 74,538,626 (+)NCBI
Celera1171,257,632 - 71,518,401 (+)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8790420   PMID:17678857   PMID:25724910   PMID:27164707   PMID:27470512  


Genomics

Comparative Map Data
Fgf12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21171,997,049 - 72,564,965 (+)NCBI
Rnor_6.0 Ensembl1175,905,443 - 76,168,989 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01175,606,360 - 76,171,078 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01178,647,628 - 79,212,339 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41174,208,696 - 74,481,037 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11174,266,284 - 74,538,626 (+)NCBI
Celera1171,257,632 - 71,518,401 (+)NCBICelera
Cytogenetic Map11q22NCBI
FGF12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3192,139,395 - 192,767,764 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl3192,139,390 - 192,767,764 (-)EnsemblGRCh38hg38GRCh38
GRCh383192,139,390 - 192,727,541 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373191,857,179 - 192,445,330 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363193,342,413 - 193,928,066 (-)NCBINCBI36hg18NCBI36
Build 343193,342,427 - 193,608,714NCBI
Celera3190,287,307 - 190,871,367 (-)NCBI
Cytogenetic Map3q28-q29NCBI
HuRef3189,257,496 - 189,843,496 (-)NCBIHuRef
CHM1_13191,820,291 - 192,408,216 (-)NCBICHM1_1
Fgf12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391627,976,535 - 28,571,995 (-)NCBIGRCm39mm39
GRCm39 Ensembl1627,978,850 - 28,571,820 (-)Ensembl
GRCm381628,157,783 - 28,753,243 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1628,160,098 - 28,753,068 (-)EnsemblGRCm38mm10GRCm38
MGSCv371628,160,184 - 28,753,288 (-)NCBIGRCm37mm9NCBIm37
MGSCv361628,075,331 - 28,672,949 (-)NCBImm8
Celera1628,680,820 - 29,265,446 (-)NCBICelera
Cytogenetic Map16B2NCBI
cM Map1619.38NCBI
Fgf12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542016,070,096 - 16,306,103 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542015,783,184 - 16,310,743 (+)NCBIChiLan1.0ChiLan1.0
FGF12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13199,776,475 - 200,359,141 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3199,778,545 - 200,358,744 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03189,430,811 - 190,017,254 (-)NCBIMhudiblu_PPA_v0panPan3
FGF12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13423,818,445 - 24,357,825 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3423,819,686 - 24,357,373 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3427,906,449 - 28,448,823 (-)NCBI
ROS_Cfam_1.03423,761,357 - 24,303,983 (-)NCBI
UMICH_Zoey_3.13423,789,790 - 24,338,922 (-)NCBI
UNSW_CanFamBas_1.03423,765,747 - 24,309,079 (-)NCBI
UU_Cfam_GSD_1.03424,006,536 - 24,549,544 (-)NCBI
Fgf12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602121,869,101 - 122,376,824 (-)NCBI
SpeTri2.0NW_0049367111,873,030 - 2,378,028 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGF12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13129,240,067 - 129,817,466 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113129,237,500 - 129,817,992 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213138,752,214 - 138,983,183 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FGF12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11586,252,816 - 86,836,363 (-)NCBI
Vero_WHO_p1.0NW_02366604159,914,424 - 60,500,806 (-)NCBI
Fgf12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473064,743,724 - 65,288,816 (+)NCBI

Position Markers
D11Mco1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01175,980,425 - 75,980,660NCBIRnor6.0
Rnor_5.01179,022,025 - 79,022,260UniSTSRnor5.0
RGSC_v3.41174,287,096 - 74,287,332RGDRGSC3.4
RGSC_v3.41174,287,097 - 74,287,332UniSTSRGSC3.4
RGSC_v3.11174,344,685 - 74,344,921RGD
Celera1171,329,739 - 71,329,974UniSTS
Cytogenetic Map11q22UniSTS
D11Arb13  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01176,060,599 - 76,060,781NCBIRnor6.0
Rnor_5.01179,102,266 - 79,102,448UniSTSRnor5.0
RGSC_v3.41174,367,678 - 74,367,862RGDRGSC3.4
RGSC_v3.41174,367,680 - 74,367,862UniSTSRGSC3.4
RGSC_v3.11174,425,267 - 74,425,451RGD
Celera1171,409,911 - 71,410,093UniSTS
Cytogenetic Map11q22UniSTS
D11Got112  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01176,068,871 - 76,069,076NCBIRnor6.0
Rnor_5.01179,110,538 - 79,110,743UniSTSRnor5.0
RGSC_v3.41174,375,952 - 74,376,157UniSTSRGSC3.4
Celera1171,418,099 - 71,418,304UniSTS
Cytogenetic Map11q22UniSTS
RH142893  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01175,909,150 - 75,909,261NCBIRnor6.0
Rnor_5.01178,950,750 - 78,950,861UniSTSRnor5.0
RGSC_v3.41174,212,403 - 74,212,514UniSTSRGSC3.4
Celera1171,261,339 - 71,261,450UniSTS
RH 3.4 Map11580.9UniSTS
Cytogenetic Map11q22UniSTS
BF397888  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01176,020,547 - 76,020,697NCBIRnor6.0
Rnor_5.01179,062,147 - 79,062,297UniSTSRnor5.0
RGSC_v3.41174,327,526 - 74,327,676UniSTSRGSC3.4
Celera1171,369,806 - 71,369,956UniSTS
RH 3.4 Map11595.9UniSTS
Cytogenetic Map11q22UniSTS
RH140156  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01176,168,871 - 76,169,071NCBIRnor6.0
Rnor_5.01179,210,132 - 79,210,332UniSTSRnor5.0
RGSC_v3.41174,481,117 - 74,481,317UniSTSRGSC3.4
Celera1171,518,481 - 71,518,681UniSTS
Cytogenetic Map11q22UniSTS
RH140530  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01176,168,829 - 76,168,987NCBIRnor6.0
Rnor_5.01179,210,090 - 79,210,248UniSTSRnor5.0
RGSC_v3.41174,481,075 - 74,481,233UniSTSRGSC3.4
Celera1171,518,439 - 71,518,597UniSTS
RH 3.4 Map11593.5UniSTS
Cytogenetic Map11q22UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111901627290463843Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111947517979734728Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112831466586994795Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)113043533986714631Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113215552082443118Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113590063480900634Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114309033886714631Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114658320986714631Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114726402386994547Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114726402386994547Rat
4889859Pur28Proteinuria QTL 2819.50.001total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)114790104978471527Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115785881090463843Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115994302390463843Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)116010984287141948Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)116265336586714475Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116265336586714483Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116449467190463843Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116934231986312439Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116964970890463843Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117272002986994795Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:29
Interacting mature miRNAs:29
Transcripts:ENSRNOT00000002650, ENSRNOT00000071586
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 43 68 18 19 1
Low 3 40 24 19 24 8 10 6 17 22 10 8
Below cutoff 17 17 17 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000002650   ⟹   ENSRNOP00000002650
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1175,905,443 - 76,168,791 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000071586   ⟹   ENSRNOP00000066842
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1176,147,205 - 76,168,989 (+)Ensembl
RefSeq Acc Id: NM_130814   ⟹   NP_570827
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21172,298,947 - 72,562,468 (+)NCBI
Rnor_6.01175,905,443 - 76,168,791 (+)NCBI
Rnor_5.01178,647,628 - 79,212,339 (+)NCBI
RGSC_v3.41174,208,696 - 74,481,037 (+)RGD
Celera1171,257,632 - 71,518,401 (+)RGD
Sequence:
RefSeq Acc Id: XM_017597854   ⟹   XP_017453343
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21172,188,575 - 72,564,757 (+)NCBI
Rnor_6.01175,795,160 - 76,171,078 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597855   ⟹   XP_017453344
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21171,997,049 - 72,564,965 (+)NCBI
Rnor_6.01175,606,360 - 76,171,078 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039087922   ⟹   XP_038943850
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21172,296,990 - 72,420,443 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_570827   ⟸   NM_130814
- UniProtKB: P61150 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017453344   ⟸   XM_017597855
- Peptide Label: isoform X2
- UniProtKB: P61150 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017453343   ⟸   XM_017597854
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000002650   ⟸   ENSRNOT00000002650
RefSeq Acc Id: ENSRNOP00000066842   ⟸   ENSRNOT00000071586
RefSeq Acc Id: XP_038943850   ⟸   XM_039087922
- Peptide Label: isoform X3

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620163 AgrOrtholog
Ensembl Genes ENSRNOG00000001931 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000002650 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000066842 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002650 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000071586 UniProtKB/TrEMBL
InterPro FGF12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Fibroblast_GF_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL1/FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:170630 UniProtKB/Swiss-Prot
NCBI Gene 170630 ENTREZGENE
PANTHER PTHR11486 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11486:SF17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fgf12 PhenoGen
PRINTS HBGFFGF UniProtKB/Swiss-Prot
PROSITE HBGF_FGF UniProtKB/Swiss-Prot
SMART FGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt FGF12_RAT UniProtKB/Swiss-Prot
  M0RBB2_RAT UniProtKB/TrEMBL
  P61150 ENTREZGENE
UniProt Secondary O35339 UniProtKB/Swiss-Prot
  P70376 UniProtKB/Swiss-Prot
  Q924B4 UniProtKB/Swiss-Prot
  Q92912 UniProtKB/Swiss-Prot
  Q93001 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-08-06 Fgf12  fibroblast growth factor 12      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN) 632803
gene_product member of the fibroblast growth factor family 632803