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Gene: Ccnd2 (cyclin D2) Rattus norvegicus
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Symbol: Ccnd2
Name: cyclin D2
Description: Exhibits protein kinase binding activity. Predicted to contribute to protein kinase activity. Involved in several processes, including response to cAMP; response to estradiol; and response to testosterone. Predicted to localize to several cellular components, including the cyclin D2-CDK4 complex; cytosol; and nucleus. Used to study transitional cell carcinoma. Biomarker of colon cancer; glaucoma; impotence; and nephritis. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Orthologous to human CCND2 (cyclin D2); PARTICIPATES IN G1/S transition pathway; cell cycle pathway, mitotic; Jak-Stat signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: G1/S-specific cyclin-D2; LOC297611; vin-1 proto-oncogene
Orthologs:
Homo sapiens (human) : CCND2 (cyclin D2)  HGNC  Alliance
Mus musculus (house mouse) : Ccnd2 (cyclin D2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnd2 (cyclin D2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCND2 (cyclin D2)
Canis lupus familiaris (dog) : CCND2 (cyclin D2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccnd2 (cyclin D2)
Sus scrofa (pig) : CCND2 (cyclin D2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04159,674,885 - 159,697,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04231,905,449 - 231,927,999 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,523,817 - 163,546,501 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14163,768,752 - 163,791,437 (-)NCBI
Celera4148,681,937 - 148,704,301 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ccnd2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621083
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.