Trim28 (tripartite motif-containing 28)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Trim28 (tripartite motif-containing 28) Rattus norvegicus

Analyze

Symbol:

Trim28

Name:

tripartite motif-containing 28

RGD ID:

620289

Description:

Predicted to have several functions, including promoter-specific chromatin binding activity; protein domain specific binding activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including DNA metabolic process; negative regulation of viral process; and regulation of nucleobase-containing compound metabolic process. Predicted to localize to chromatin and nucleus. Orthologous to human TRIM28 (tripartite motif containing 28); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

E3 SUMO-protein ligase TRIM28; Kap1; KRAB-associated protein 1; Krip1; nuclear corepressor KAP-1; RING-type E3 ubiquitin transferase TIF1-beta; TIF1-beta; Tif1b; transcription intermediary factor 1-beta; tripartite motif protein 28; tripartite motif-containing protein 28

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	TRIM28 (tripartite motif containing 28)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Trim28 (tripartite motif-containing 28)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Trim28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	TRIM28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	TRIM28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Trim28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	TRIM28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	TRIM28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Trim28 (tripartite motif containing 28)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	TRIM28 (tripartite motif containing 28)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Mus musculus (house mouse):	Trim28 (tripartite motif-containing 28)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|TreeFam)
Drosophila melanogaster (fruit fly):	bon	Alliance	DIOPT (InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|TreeFam)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	73,652,441 - 73,659,388 (+)	NCBI
Rnor_6.0 Ensembl	1	65,544,373 - 65,551,043 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	65,544,369 - 65,551,043 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	66,355,602 - 66,362,276 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	72,892,399 - 72,899,070 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	72,973,571 - 72,973,906 (-)	NCBI
Celera	1	60,180,424 - 60,187,048 (-)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atherosclerosis (ISO)

Colorectal Neoplasms (ISO)

nephroblastoma (ISO)

prostate cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (ISO)

(S)-nicotine (ISO)

1,2-dimethylhydrazine (ISO)

1,4-dichlorobenzene (ISO)

17alpha-ethynylestradiol (EXP)

17beta-hydroxy-17-methylestra-4,9,11-trien-3-one (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

4-amino-2,6-dinitrotoluene (EXP)

aflatoxin B1 (ISO)

ammonium chloride (EXP)

aphidicolin (ISO)

bisphenol A (EXP)

bleomycin A2 (ISO)

C60 fullerene (EXP)

caffeine (ISO)

camptothecin (ISO)

captan (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clofibrate (ISO)

cocaine (EXP)

deoxynivalenol (ISO)

diazinon (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

diethylstilbestrol (EXP)

doxorubicin (ISO)

elemental selenium (ISO)

enzyme inhibitor (ISO)

ethanol (ISO)

folic acid (ISO)

folpet (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

L-ascorbic acid (ISO)

lead(0) (ISO)

lead(2+) (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

miconazole (ISO)

N-acetyl-L-cysteine (ISO)

nicotine (ISO)

paracetamol (ISO)

pentachlorophenol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

potassium chromate (ISO)

resveratrol (ISO)

selenium atom (ISO)

sodium dichromate (ISO)

tetrachloromethane (ISO)

thimerosal (ISO)

thioacetamide (EXP)

trichloroethene (ISO)

uranium atom (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin organization (IEA)

convergent extension involved in axis elongation (ISO)

DNA methylation involved in embryo development (ISO)

DNA repair (ISO)

embryo implantation (ISO)

embryonic placenta morphogenesis (ISO)

epithelial to mesenchymal transition (ISO,ISS)

in utero embryonic development (ISO)

innate immune response (IBA,ISO)

negative regulation of DNA demethylation (ISO)

negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (ISO)

negative regulation of transcription by RNA polymerase II (ISO)

negative regulation of transcription, DNA-templated (IBA,ISO)

negative regulation of viral release from host cell (ISO)

positive regulation of DNA binding (ISO)

positive regulation of DNA methylation-dependent heterochromatin assembly (ISO,ISS)

positive regulation of DNA repair (ISO)

positive regulation of protein import into nucleus (ISO,ISS)

positive regulation of transcription, DNA-templated (IBA,ISO,ISS)

protein autophosphorylation (ISO)

protein phosphorylation (ISO)

protein sumoylation (IBA,IEA,ISO)

protein ubiquitination (IEA)

Ras protein signal transduction (ISO,ISS)

regulation of genetic imprinting (ISO)

Cellular Component

chromatin (IBA,ISO)

euchromatin (ISO)

heterochromatin (ISO)

nucleolus (ISO)

nucleoplasm (IBA,ISO)

nucleus (ISO,ISS)

protein-containing complex (ISO)

RNA polymerase II transcription regulator complex (IBA,ISO,ISS)

Molecular Function

chromatin binding (ISO)

chromo shadow domain binding (ISO)

DNA binding (IBA,ISO)

Krueppel-associated box domain binding (ISO,ISS)

promoter-specific chromatin binding (IBA,ISO,ISS)

protein binding (ISO)

protein kinase activity (ISO)

SUMO transferase activity (ISO)

transcription coactivator activity (ISO,ISS)

transcription corepressor activity (IBA,ISO)

ubiquitin protein ligase binding (ISO)

ubiquitin-protein transferase activity (IBA,ISO)

zinc ion binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

p53 signaling pathway (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA data from the GO Consortium
3.	Huang Z, etal., J Biol Chem 1999 Mar 19;274(12):7640-8.
4.	MGD data from the GO Consortium
5.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7.	RGD automated data pipeline
8.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8769649	PMID:8986806	PMID:9016654	PMID:10562550	PMID:10653693	PMID:11226167	PMID:11331580	PMID:11331592	PMID:12477932	PMID:15469996	PMID:15882967	PMID:17178852
PMID:17273560	PMID:17298944	PMID:17512541	PMID:18082607	PMID:18248090	PMID:19270682	PMID:19321449	PMID:20164836	PMID:21518874	PMID:22082260	PMID:22110054	PMID:22495301
PMID:22681889	PMID:22801370	PMID:22871113	PMID:23665872	PMID:24623306	PMID:24625528	PMID:25002582	PMID:27029610	PMID:30053369

Genomics

Comparative Map Data

Trim28
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	1	73,652,441 - 73,659,388 (+)	NCBI
Rnor_6.0 Ensembl	1	65,544,373 - 65,551,043 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	1	65,544,369 - 65,551,043 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	1	66,355,602 - 66,362,276 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	1	72,892,399 - 72,899,070 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	1	72,973,571 - 72,973,906 (-)	NCBI
Celera	1	60,180,424 - 60,187,048 (-)	NCBI		Celera
Cytogenetic Map	1	q12	NCBI

TRIM28
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	19	58,544,064 - 58,550,722 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	19	58,544,064 - 58,550,722 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	19	59,055,431 - 59,062,082 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	63,747,648 - 63,753,894 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	19	63,747,647 - 63,753,894	NCBI
Celera	19	56,099,015 - 56,105,261 (+)	NCBI
Cytogenetic Map	19	q13.43	NCBI
HuRef	19	55,366,200 - 55,372,319 (+)	NCBI		HuRef
CHM1_1	19	59,049,665 - 59,055,911 (+)	NCBI		CHM1_1

Trim28
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	7	12,758,079 - 12,764,959 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	7	12,733,041 - 12,764,962 (+)	Ensembl
GRCm38	7	13,024,152 - 13,031,032 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	7	12,999,114 - 13,031,035 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	7	13,609,501 - 13,616,381 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	7	11,924,340 - 11,931,208 (+)	NCBI			mm8
Celera	7	10,651,338 - 10,658,223 (+)	NCBI		Celera
Cytogenetic Map	7	A1	NCBI

Trim28
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955584	1,148,903 - 1,156,001 (+)	NCBI	ChiLan1.0	ChiLan1.0

TRIM28
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	19	64,369,979 - 64,377,144 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	64,371,477 - 64,377,144 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	19	55,557,130 - 55,563,802 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

TRIM28
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	99,408,920 - 99,415,432 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	99,408,925 - 99,415,146 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	99,786,699 - 99,813,478 (-)	NCBI
ROS_Cfam_1.0	1	100,001,554 - 100,028,322 (-)	NCBI
UMICH_Zoey_3.1	1	99,646,919 - 99,673,683 (-)	NCBI
UNSW_CanFamBas_1.0	1	99,359,536 - 99,386,515 (-)	NCBI
UU_Cfam_GSD_1.0	1	100,114,388 - 100,141,157 (-)	NCBI

Trim28
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_ltri_2	NW_024405118	217,986,447 - 217,992,258 (-)	NCBI
SpeTri2.0	NW_004937062	126,832 - 132,938 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TRIM28
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	63,094,648 - 63,101,532 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	63,094,382 - 63,101,532 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

TRIM28
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	50,820,188 - 50,826,376 (+)	NCBI
ChlSab1.1 Ensembl	6	50,819,833 - 50,827,010 (+)	Ensembl

Trim28
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624832	49,324 - 56,113 (-)	NCBI

Position Markers

RH137168

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	65,544,483 - 65,544,690	NCBI	Rnor6.0
Rnor_5.0	1	66,355,716 - 66,355,923	UniSTS	Rnor5.0
RGSC_v3.4	1	72,892,510 - 72,892,717	UniSTS	RGSC3.4
Celera	1	60,180,535 - 60,180,742	UniSTS
Cytogenetic Map	1	q21	UniSTS

RH143061

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	65,555,613 - 65,555,726	NCBI	Rnor6.0
Rnor_5.0	1	66,366,846 - 66,366,959	UniSTS	Rnor5.0
RGSC_v3.4	1	72,903,644 - 72,903,757	UniSTS	RGSC3.4
Celera	1	60,191,344 - 60,191,457	UniSTS
RH 3.4 Map	4	624.54	UniSTS
Cytogenetic Map	1	q21	UniSTS

RH126533

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	1	65,544,391 - 65,544,593	NCBI	Rnor6.0
Rnor_5.0	1	66,355,624 - 66,355,826	UniSTS	Rnor5.0
RGSC_v3.4	1	72,892,418 - 72,892,620	UniSTS	RGSC3.4
Celera	1	60,180,443 - 60,180,645	UniSTS
Cytogenetic Map	1	q21	UniSTS

Trim28

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	18	43,889,372 - 43,890,236	NCBI	Rnor6.0
Rnor_5.0	14	46,101,219 - 46,102,083	UniSTS	Rnor5.0
RGSC_v3.4	18	44,661,266 - 44,662,130	UniSTS	RGSC3.4
Celera	18	41,074,256 - 41,075,120	UniSTS
Cytogenetic Map	1	q21	UniSTS
Cytogenetic Map	14	p11	UniSTS
Cytogenetic Map	18	q11	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1554320	Bmd1	Bone mineral density QTL 1	12.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	1	254393	86904217	Rat
631688	Hcas2	Hepatocarcinoma susceptibility QTL 2	3	0.0001	liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	1	5655769	122614963	Rat
4889451	Eae29	Experimental allergic encephalomyelitis QTL 29	5.51		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	1	5655772	85706974	Rat
1300167	Hrtrt2	Heart rate QTL 2	4.35		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	1	11314489	75844121	Rat
2313062	Bmd73	Bone mineral density QTL 73	3.9	0.0001	tibia mineral mass (VT:1000283)	cortical volumetric bone mineral density (CMO:0001730)	1	11314489	83657083	Rat
2313065	Bss67	Bone structure and strength QTL 67	3.1	0.0001	tibia area (VT:1000281)	tibia total energy absorbed before break (CMO:0001736)	1	11314489	83657083	Rat
2313069	Bss68	Bone structure and strength QTL 68	2.9	0.0001	tibia size trait (VT:0100001)	tibia total energy absorbed before break (CMO:0001736)	1	11314489	83657083	Rat
2313075	Bss66	Bone structure and strength QTL 66	3.4	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	11314489	83657083	Rat
2313077	Bss69	Bone structure and strength QTL 69	3.5	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	11314489	83657083	Rat
2313092	Bmd72	Bone mineral density QTL 72	2.5	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	1	11314489	83657083	Rat
2313097	Bss70	Bone structure and strength QTL 70	3.5	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	11314489	83657083	Rat
724520	Bp145	Blood pressure QTL 145	2.1	0.0024	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	21079305	66079305	Rat
1357400	Bw62	Body weight QTL62	4.05		inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	1	23406428	68406428	Rat
631495	Bp96	Blood pressure QTL 96	4.52		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	23406428	108057505	Rat
1358192	Ept13	Estrogen-induced pituitary tumorigenesis QTL 13	3.4		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	1	24297799	78748000	Rat
1358359	Sradr1	Stress Responsive Adrenal Weight QTL 1	4.74		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	1	25951907	130917265	Rat
1331785	Rf27	Renal function QTL 27	4.643		urine sodium amount (VT:0006274)	urine sodium level (CMO:0000129)	1	31489454	79689689	Rat
1354643	Foco2	Food consumption QTL 2	7.17	0.0001	eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	1	34449112	79449112	Rat
1354599	Bw29	Body weight QTL 29	3.46	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	1	34449112	79449112	Rat
70225	Bp58	Blood pressure QTL 58	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	34993530	173445086	Rat
1300172	Bp172	Blood pressure QTL 172	3.56		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	35377508	94364229	Rat
10059597	Bp377	Blood pressure QTL 377	3.42	0.025	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	35377692	217372257	Rat
9589820	Insglur3	Insulin/glucose ratio QTL 3	10.75	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	1	35854167	80854167	Rat
8552900	Pigfal1	Plasma insulin-like growth factor 1 level QTL 1	7.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	35854167	80854167	Rat
8552948	Pigfal11	Plasma insulin-like growth factor 1 level QTL 11	4.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	1	35854167	80854167	Rat
1331732	Srn4	Serum renin concentration QTL 4	4.467		renin activity (VT:0005581)	plasma renin activity level (CMO:0000116)	1	36033165	79689689	Rat
1331792	Rf29	Renal function QTL 29	4.589		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	1	36033165	79689689	Rat
2302059	Pia36	Pristane induced arthritis QTL 36	3.8	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	1	41907249	86907249	Rat
2313051	Bss57	Bone structure and strength QTL 57	3.7	0.0001	tibia strength trait (VT:1000284)	bone polar moment of inertia (CMO:0001558)	1	43579208	126240667	Rat
2313059	Bss55	Bone structure and strength QTL 55	3.2	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	1	43579208	126240667	Rat
2313072	Bss53	Bone structure and strength QTL 53	4.3	0.0001	tibia length (VT:0004357)	tibia length (CMO:0000450)	1	43579208	126240667	Rat
2313078	Bss54	Bone structure and strength QTL 54	3.5	0.0001	tibia area (VT:1000281)	tibia midshaft cross-sectional area (CMO:0001717)	1	43579208	126240667	Rat
2313094	Bss58	Bone structure and strength QTL 58	3.7	0.0001	tibia strength trait (VT:1000284)	tibia total energy absorbed before break (CMO:0001736)	1	43579208	126240667	Rat
2313098	Bmd70	Bone mineral density QTL 70	3.6	0.0001	tibia mineral mass (VT:1000283)	cortical volumetric bone mineral density (CMO:0001730)	1	43579208	126240667	Rat
2313099	Bss56	Bone structure and strength QTL 56	2.4	0.0001	tibia size trait (VT:0100001)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	1	43579208	126240667	Rat
1331778	Rf28	Renal function QTL 28	4.66		urine potassium amount (VT:0010539)	urine potassium excretion rate (CMO:0000761)	1	46113461	79689689	Rat
2313402	Anxrr24	Anxiety related response QTL 24			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	1	49147799	156446783	Rat
4889962	Bss94	Bone structure and strength QTL 94	3.8		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	49547328	83657083	Rat
1578649	Bmd8	Bone mineral density QTL 8	4.9		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	1	49578577	94578577	Rat
1578654	Bss10	Bone structure and strength QTL 10	4		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	1	49578577	169852184	Rat
634314	Niddm44	Non-insulin dependent diabetes mellitus QTL 44			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	1	49578693	217054291	Rat
6903308	Scl36	Serum cholesterol QTL 36	2	0.0125	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	1	50522714	94225616	Rat
4889919	Bss86	Bone structure and strength QTL 86	4.1		tibia area (VT:1000281)	tibia midshaft total cross-sectional area (CMO:0001715)	1	53851348	83657083	Rat
4889929	Bss87	Bone structure and strength QTL 87	6.7		tibia area (VT:1000281)	tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)	1	53851348	83657083	Rat
61342	Bp27	Blood pressure QTL 27	3.4	0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	57761301	104391981	Rat
2300164	Bmd44	Bone mineral density QTL 44	5.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	1	58209327	103209327	Rat
2298545	Neuinf8	Neuroinflammation QTL 8	4.6		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	1	58354072	161711996	Rat
7421628	Bp361	Blood pressure QTL 361		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	64588516	125875986	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	130
Count of miRNA genes:	98
Interacting mature miRNAs:	107
Transcripts:	ENSRNOT00000029996
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	41	11	8
Low
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053916	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006228108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000029	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U95041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000029996 ⟹ ENSRNOP00000031061

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	1	65,544,373 - 65,551,043 (-)	Ensembl

RefSeq Acc Id:

NM_053916 ⟹ NP_446368

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	73,652,709 - 73,659,381 (+)	NCBI
Rnor_6.0	1	65,544,372 - 65,551,043 (-)	NCBI
Rnor_5.0	1	66,355,602 - 66,362,276 (-)	NCBI
RGSC_v3.4	1	72,892,399 - 72,899,070 (-)	RGD
Celera	1	60,180,424 - 60,187,048 (-)	RGD

Sequence:

show sequence

GCGGTTGTTCGCAATTCTTGCGGCGCGAGTCTCAGCAGCAAGGGAGGAGGCGGCGCGGGTGGCG
GCGCCGTCGTCTGTAGAGAGGCCGGCAGCCAGCGGCTTGGCCGCATCTCGGCAGCGCCTGGGGC
GCGGCGGGCGTCGGCCCAGGAGACGCGTGGCGGCGCTCGGCCTCGCGGCATCGGCGGCTGCCTG
GCCGTTGGCGGCGAGCGCACTTGCGCCTGCGCAGCGGGCTCGGTGCCCCTCCTCCCCTGGGCGG
CCCCCCCAACCCCCCGGCGGCGTGTGAATGGCGGCCTCGGCGGCGGCGGCGACTGCGGCGGCCT
CGGCCGCGACGGCCGCGTCAGCGGCCTCTGGTAGCCCAGGGTCGGGCGAAGGCTCGGCGGGCGG
TGAGAAGCGCCCCGCTGCCTCTTCAGCCGCGGCGGCCTCGGCCTCCGCGTCGTCCCCTGCGGGG
GGCGGTGGCGAGGCGCAGGAGCTTTTGGAGCACTGCGGCGTGTGTCGCGAGCGCTTGCGGCCTG
AGCGGGATCCTCGGCTGCTGCCCTGTCTGCATTCGGCCTGTAGTGCCTGCCTTGGCCCCGCTAC
ACCCGCCGCAGCTAATAATTCGGGGGATGGCGGCTCGGCGGGCGACGGCGCTATGGTGGATTGT
CCAGTGTGCAAACAACAGTGCTACTCCAAAGACATCGTGGAGAATTACTTTATGCGTGATAGTG
GCAGTAAGGCCTCTTCTGATTCCCAGGATGCTAACCAGTGCTGCACTAGCTGTGAAGATAACGC
CCCAGCCACTAGCTATTGTGTGGAGTGCTCTGAACCACTGTGTGAGACCTGTGTGGAGGCTCAC
CAGCGGGTGAAATACACCAAGGATCACACTGTGCGCTCCACGGGTCCTGCTAAGACTCGAGATG
GAGAACGAACAGTCTATTGTAATGTGCACAAGCATGAACCCCTTGTGCTGTTTTGTGAGAGCTG
TGACACGCTCACTTGCCGGGACTGCCAACTCAATGCTCACAAGGACCACCAGTACCAATTCTTG
GAAGATGCAGTAAGGAACCAACGTAAACTCTTGGCTTCACTGGTGAAACGTCTTGGGGACAAAC
ATGCCACACTGCAGAAAAACACCAAGGAGGTTCGAAGCTCGATCCGCCAGGTGTCTGATGTGCA
GAAGCGAGTGCAGGTTGATGTGAAGATGGCCATTCTGCAGATCATGAAGGAGCTGAATAAACGG
GGACGAGTTCTGGTCAATGATGCCCAGAAGGTGACTGAGGGTCAGCAGGAACGTCTGGAGCGTC
AGCACTGGACCATGACCAAAATCCAGAAGCACCAGGAACACATTTTGCGCTTTGCCTCTTGGGC
TTTGGAGAGTGATAACAATACAGCCCTCTTGCTCTCTAAGAAGCTGATTTATTTCCAGCTGCAT
CGGGCCCTCAAAATGATTGTGGATCCTGTGGAGCCTCATGGTGAGATGAAGTTTCAGTGGGATC
TCAATGCCTGGACCAAGAGTGCTGAAGCCTTTGGTAAGATTGTGGCTGAGCGTCCTGGTACAAA
CTCCACGGGTCCTGGGCCCATGGCTCCTCCAAGAGCCCCAGGCCCCCTAAGCAAGCAAGGTTCT
GGTAGTAGCCAGCCCATGGAAGTACAAGAGGGCTATGGCTTTGGGACAGATGATCCCTACTCAA
GTGCAGAGCCACATGTATCAGGCATGAAGCGGTCCCGCTCTGGTGAGGGAGAAGTAAGTGGCCT
CATGAGGAAGGTGCCACGTGTGAGCCTTGAACGCCTGGATCTGGATCTCACCTCTGATAGCCAG
CCACCAGTCTTCAAGGTCTTTCCTGGAAGCACCACTGAGGACTACAATCTAATTGTTATTGAGC
GTGGTGCTGCTGCAGCAGCCGCTGGCCAGGCTGGGACTGTGCCACCAGGAGCCCCTGGTGCCCC
ACCCCTGCCTGGCATGGCCATTGTCAAGGAAGAAGAGACAGAAGCTGCTATTGGAGCCCCTCCT
GCTGCCCCTGAGGGGCCTGAAACCAAGCCTGTGTTGATGGCTCTGACTGAAGGCCCTGGGGCTG
AGGGACCTCGTCTAGCTTCACCTAGTGGCAGTACCAGCTCAGGCTTGGAGGTGGTAGCTCCTGA
GGTTACCTCAGCCCCAGTAAGTGGGCCAGGTATCCTGGATGACAGTGCCACTATCTGCCGTGTA
TGCCAGAAGCCAGGTGACCTGGTCATGTGCAACCAGTGCGAGTTTTGCTTCCACCTGGATTGTC
ACCTCCCTTCCCTGCAGGATGTTCCAGGGGAGGAATGGAGTTGCTCACTCTGCCACGTGCTCCC
TGATCTAAAGGAGGAAGATGGAAGCCTTAGCTTGGATGGAGCAGATAGCACTGGTGTGGTAGCT
AAACTCTCACCAGCCAACCAGCGGAAATGTGAGCGTGTTCTGCTGGCCCTTTTCTGCCATGAAC
CGTGCCGCCCCTTGCATCAGCTGGCTACCGACTCTACATTCTCCATGGAGCAGCCTGGTGGTAC
CCTAGACCTGACCTTGATTCGTGCTCGCCTCCAAGAGAAGCTGTCACCTCCTTATAGCTCCCCC
CAGGAGTTTGCCCAGGATGTGGGCCGCATGTTCAAACAGTTCAATAAGCTGACTGAGGACAAGG
CAGATGTTCAGTCCATCATCGGCCTCCAGCGCTTCTTTGAGACACGAATGAATGATGCCTTTGG
TGACACCAAGTTTTCTGCTGTGCTGGTAGAACCACCACCACTGAACCTTCCCAGTGCTGGCCTA
AGTTCTCAGGAGCTGTCTGGTCCTGGTGATGGCCCCTGAAGCTGGGGCTCTTGTGGTCAGCCCA
GTCCAGCTCTGGTCTCTGTATTTTCAACCCATACCCTGTCCTTCCTCTGGTGGCCTGACTACCT
GTTCTTGCTGGCCCCATCCCTCAGTCCCTCCTCACAAAATGGTTTTTACTTCTGTGGATTTAAT
AAAAACTTCACTGAGTCAGTCGCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006228108 ⟹ XP_006228170

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	1	73,652,441 - 73,659,388 (+)	NCBI
Rnor_6.0	1	65,544,369 - 65,551,039 (-)	NCBI
Rnor_5.0	1	66,355,602 - 66,362,276 (-)	NCBI

Sequence:

show sequence

TTGTTCGCAATTCTTGCGGCGCGAGTCTCAGCAGCAAGGGAGGAGGCGGCGCGGGTGGCGGCGC
CGTCGTCTGTAGAGAGGCCGGCAGCCAGCGGCTTGGCCGCATCTCGGCAGCGCCTGGGGCGCGG
CGGGCGTCGGCCCAGGAGACGCGTGGCGGCGCTCGGCCTCGCGGCATCGGCGGCTGCCTGGCCG
TTGGCGGCGAGCGCACTTGCGCCTGCGCAGCGGGCTCGGTGCCCCTCCTCCCCTGGGCGGCCCC
CCCAACCCCCCGGCGGCGTGTGAATGGCGGCCTCGGCGGCGGCGGCGACTGCGGCGGCCTCGGC
CGCGACGGCCGCGTCAGCGGCCTCTGGTAGCCCAGGGTCGGGCGAAGGCTCGGCGGGCGGTGAG
AAGCGCCCCGCTGCCTCTTCAGCCGCGGCGGCCTCGGCCTCCGCGTCGTCCCCTGCGGGGGGCG
GTGGCGAGGCGCAGGAGCTTTTGGAGCACTGCGGCGTGTGTCGCGAGCGCTTGCGGCCTGAGCG
GGATCCTCGGCTGCTGCCCTGTCTGCATTCGGCCTGTAGTGCCTGCCTTGGCCCCGCTACACCC
GCCGCAGCTAATAATTCGGGGGATGGCGGCTCGGCGGGCGACGGCGCTATGGTGGATTGTCCAG
TGTGCAAACAACAGTGCTACTCCAAAGACATCGTGGAGAATTACTTTATGCGTGATAGTGGCAG
TAAGGCCTCTTCTGATTCCCAGGATGCTAACCAGTGCTGCACTAGCTGTGAAGATAACGCCCCA
GCCACTAGCTATTGTGTGGAGTGCTCTGAACCACTGTGTGAGACCTGTGTGGAGGCTCACCAGC
GGGTGAAATACACCAAGGATCACACTGTGCGCTCCACGGGTCCTGCTAAGACTCGAGATGGAGA
ACGAACAGTCTATTGTAATGTGCACAAGCATGAACCCCTTGTGCTGTTTTGTGAGAGCTGTGAC
ACGCTCACTTGCCGGGACTGCCAACTCAATGCTCACAAGGACCACCAGTACCAATTCTTGGAAG
ATGCAGTAAGGAACCAACGTAAACTCTTGGCTTCACTGGTGAAACGTCTTGGGGACAAACATGC
CACACTGCAGAAAAACACCAAGGAGGTTCGAAGCTCGATCCGCCAGGTGTCTGATGTGCAGAAG
CGAGTGCAGGTTGATGTGAAGATGGCCATTCTGCAGATCATGAAGGAGCTGAATAAACGGGGAC
GAGTTCTGGTCAATGATGCCCAGAAGGTGACTGAGGGTCAGCAGGAACGTCTGGAGCGTCAGCA
CTGGACCATGACCAAAATCCAGAAGCACCAGGAACACATTTTGCGCTTTGCCTCTTGGGCTTTG
GAGAGTGATAACAATACAGCCCTCTTGCTCTCTAAGAAGCTGATTTATTTCCAGCTGCATCGGG
CCCTCAAAATGATTGTGGATCCTGTGGAGCCTCATGGTGAGATGAAGTTTCAGTGGGATCTCAA
TGCCTGGACCAAGAGTGCTGAAGCCTTTGGTAAGATTGTGGCTGAGCGTCCTGGTACAAACTCC
ACGGGTCCTGGGCCCATGGCTCCTCCAAGAGCCCCAGGCCCCCTAAGCAAGCAAGGTTCTGGTA
GTAGCCAGCCCATGGAAGTACAAGAGGGCTATGGCTTTGGGACAGATGATCCCTACTCAAGTGC
AGAGCCACATGTATCAGGCATGAAGCGGTCCCGCTCTGGTGAGGGAGAAGTAAGTGGCCTCATG
AGGAAGGTGCCACGTGTGAGCCTTGAACGCCTGGATCTGGATCTCACCTCTGATAGCCAGCCAC
CAGTCTTCAAGGTCTTTCCTGGAAGCACCACTGAGGACTACAATCTAATTGTTATTGAGCGTGG
TGCTGCTGCAGCAGCCGCTGGCCAGGCTGGGACTGTGCCACCAGGAGCCCCTGGTGCCCCACCC
CTGCCTGGCATGGCCATTGTCAAGGAAGAAGAGACAGAAGCTGCTATTGGAGCCCCTCCTGCTG
CCCCTGAGGGGCCTGAAACCAAGCCTGTGTTGATGGCTCTGACTGAAGGCCCTGGGGCTGAGGG
ACCTCGTCTAGCTTCACCTAGTGGCAGTACCAGCTCAGGCTTGGAGGTGGTAGCTCCTGAGGTT
ACCTCAGCCCCAGTAAGTGGGCCAGGTATCCTGGATGACAGTGCCACTATCTGCCGTGTATGCC
AGAAGCCAGGTGACCTGGTCATGTGCAACCAGTGCGAGTTTTGCTTCCACCTGGATTGTCACCT
CCCTTCCCTGCAGGATGTTCCAGGGGAGGAATGGAGTTGCTCACTCTGCCACGTGCTCCCTGAT
CTAAAGGAGGAAGATGGAAGCCTTAGCTTGGATGGAGCAGATAGCACTGGTGTGGTAGCTAAAC
TCTCACCAGCCAACCAGCGGAAATGTGAGCGTGTTCTGCTGGCCCTTTTCTGCCATGAACCGTG
CCGCCCCTTGCATCAGCTGGCTACCGACTCTACATTCTCCATGGTGAGTAGTCCCAGAATAGGA
GAGGTTGCAGGTGTCAAGTTGGTAGCCCCACTCAATGTCTGTTGTCTCTCCCTGCAGGAGCAGC
CTGGTGGTACCCTAGACCTGACCTTGATTCGTGCTCGCCTCCAAGAGAAGCTGTCACCTCCTTA
TAGCTCCCCCCAGGAGTTTGCCCAGGATGTGGGCCGCATGTTCAAACAGTTCAATAAGCTGACT
GAGGACAAGGCAGATGTTCAGTCCATCATCGGCCTCCAGCGCTTCTTTGAGACACGAATGAATG
ATGCCTTTGGTGACACCAAGTTTTCTGCTGTGCTGGTAGAACCACCACCACTGAACCTTCCCAG
TGCTGGCCTAAGTTCTCAGGAGCTGTCTGGTCCTGGTGATGGCCCCTGAAGCTGGGGCTCTTGT
GGTCAGCCCAGTCCAGCTCTGGTCTCTGTATTTTCAACCCATACCCTGTCCTTCCTCTGGTGGC
CTGACTACCTGTTCTTGCTGGCCCCATCCCTCAGTCCCTCCTCACAAAATGGTTTTTACTTCTG
TGGATTTAATAAAAACTTCACTGAGTCAGTCGCTCATTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_446368	(Get FASTA)	NCBI Sequence Viewer
	XP_006228170	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB51518	(Get FASTA)	NCBI Sequence Viewer
	AAI66843	(Get FASTA)	NCBI Sequence Viewer
	O08629	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_446368 ⟸ NM_053916

- UniProtKB:

O08629 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAASAAAATAAASAATAASAASGSPGSGEGSAGGEKRPAASSAAAASASASSPAGGGGEAQELL
EHCGVCRERLRPERDPRLLPCLHSACSACLGPATPAAANNSGDGGSAGDGAMVDCPVCKQQCYS
KDIVENYFMRDSGSKASSDSQDANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDH
TVRSTGPAKTRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRK
LLASLVKRLGDKHATLQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQ
KVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP
VEPHGEMKFQWDLNAWTKSAEAFGKIVAERPGTNSTGPGPMAPPRAPGPLSKQGSGSSQPMEVQ
EGYGFGTDDPYSSAEPHVSGMKRSRSGEGEVSGLMRKVPRVSLERLDLDLTSDSQPPVFKVFPG
STTEDYNLIVIERGAAAAAAGQAGTVPPGAPGAPPLPGMAIVKEEETEAAIGAPPAAPEGPETK
PVLMALTEGPGAEGPRLASPSGSTSSGLEVVAPEVTSAPVSGPGILDDSATICRVCQKPGDLVM
CNQCEFCFHLDCHLPSLQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRK
CERVLLALFCHEPCRPLHQLATDSTFSMEQPGGTLDLTLIRARLQEKLSPPYSSPQEFAQDVGR
MFKQFNKLTEDKADVQSIIGLQRFFETRMNDAFGDTKFSAVLVEPPPLNLPSAGLSSQELSGPG
DGP

hide sequence

RefSeq Acc Id:

XP_006228170 ⟸ XM_006228108

- Peptide Label:

isoform X1

- Sequence:

show sequence

MAASAAAATAAASAATAASAASGSPGSGEGSAGGEKRPAASSAAAASASASSPAGGGGEAQELL
EHCGVCRERLRPERDPRLLPCLHSACSACLGPATPAAANNSGDGGSAGDGAMVDCPVCKQQCYS
KDIVENYFMRDSGSKASSDSQDANQCCTSCEDNAPATSYCVECSEPLCETCVEAHQRVKYTKDH
TVRSTGPAKTRDGERTVYCNVHKHEPLVLFCESCDTLTCRDCQLNAHKDHQYQFLEDAVRNQRK
LLASLVKRLGDKHATLQKNTKEVRSSIRQVSDVQKRVQVDVKMAILQIMKELNKRGRVLVNDAQ
KVTEGQQERLERQHWTMTKIQKHQEHILRFASWALESDNNTALLLSKKLIYFQLHRALKMIVDP
VEPHGEMKFQWDLNAWTKSAEAFGKIVAERPGTNSTGPGPMAPPRAPGPLSKQGSGSSQPMEVQ
EGYGFGTDDPYSSAEPHVSGMKRSRSGEGEVSGLMRKVPRVSLERLDLDLTSDSQPPVFKVFPG
STTEDYNLIVIERGAAAAAAGQAGTVPPGAPGAPPLPGMAIVKEEETEAAIGAPPAAPEGPETK
PVLMALTEGPGAEGPRLASPSGSTSSGLEVVAPEVTSAPVSGPGILDDSATICRVCQKPGDLVM
CNQCEFCFHLDCHLPSLQDVPGEEWSCSLCHVLPDLKEEDGSLSLDGADSTGVVAKLSPANQRK
CERVLLALFCHEPCRPLHQLATDSTFSMVSSPRIGEVAGVKLVAPLNVCCLSLQEQPGGTLDLT
LIRARLQEKLSPPYSSPQEFAQDVGRMFKQFNKLTEDKADVQSIIGLQRFFETRMNDAFGDTKF
SAVLVEPPPLNLPSAGLSSQELSGPGDGP

hide sequence

RefSeq Acc Id:

ENSRNOP00000031061 ⟸ ENSRNOT00000029996

Protein Domains

Bromo

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13689671

Promoter ID:

EPDNEW_R196

Type:

initiation region

Name:

Trim28_2

Description:

tripartite motif-containing 28

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R197

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	65,550,772 - 65,550,832	EPDNEW

RGD ID:

13689672

Promoter ID:

EPDNEW_R197

Type:

initiation region

Name:

Trim28_1

Description:

tripartite motif-containing 28

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_R196

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	1	65,551,068 - 65,551,128	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

Visual

CSV

TAB

Printer

Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

Visual

CSV

TAB

Printer

Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
1	72898588	72898589	C	G	snv	SS/JrHsdMcwi (MCW)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620289	AgrOrtholog
Ensembl Genes	ENSRNOG00000027487	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000031061	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000029996	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.20.920.10	UniProtKB/Swiss-Prot
	3.30.40.10	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:9028761	IMAGE-MGC_LOAD
InterPro	Bbox_C	UniProtKB/Swiss-Prot
	Bromodomain	UniProtKB/Swiss-Prot
	Bromodomain-like_sf	UniProtKB/Swiss-Prot
	KAP1	UniProtKB/Swiss-Prot
	TIF1beta_RING-HC	UniProtKB/Swiss-Prot
	Zinc_finger_PHD-type_CS	UniProtKB/Swiss-Prot
	Znf_B-box	UniProtKB/Swiss-Prot
	Znf_FYVE_PHD	UniProtKB/Swiss-Prot
	Znf_PHD	UniProtKB/Swiss-Prot
	Znf_PHD-finger	UniProtKB/Swiss-Prot
	Znf_RING	UniProtKB/Swiss-Prot
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot
KEGG Report	rno:116698	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:188735	IMAGE-MGC_LOAD
NCBI Gene	116698	ENTREZGENE
PANTHER	PTHR25462:SF274	UniProtKB/Swiss-Prot
Pfam	PHD	UniProtKB/Swiss-Prot
	zf-B_box	UniProtKB/Swiss-Prot
	zf-RING_5	UniProtKB/Swiss-Prot
PhenoGen	Trim28	PhenoGen
PROSITE	ZF_BBOX	UniProtKB/Swiss-Prot
	ZF_PHD_1	UniProtKB/Swiss-Prot
	ZF_PHD_2	UniProtKB/Swiss-Prot
	ZF_RING_2	UniProtKB/Swiss-Prot
SMART	BBC	UniProtKB/Swiss-Prot
	BBOX	UniProtKB/Swiss-Prot
	BROMO	UniProtKB/Swiss-Prot
	PHD	UniProtKB/Swiss-Prot
	RING	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF57903	UniProtKB/Swiss-Prot
UniProt	O08629	ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary	B2RYN5	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-31	Trim28	tripartite motif-containing 28	Trim28	tripartite motif protein 28	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-02-26	Trim28	tripartite motif protein 28			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Trim28	tripartite motif protein 28			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Annotations - PID (archival)