Predicted to enable several functions, including promoter-specific chromatin binding activity; protein domain specific binding activity; and ubiquitin-like protein transferase activity. Predicted to be involved in several processes, including positive regulation of DNA methylation-dependent heterochromatin formation; positive regulation of nucleobase-containing compound metabolic process; and positive regulation of protein import into nucleus. Predicted to act upstream of or within several processes, including convergent extension involved in axis elongation; negative regulation of DNA demethylation; and regulation of macromolecule biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex; euchromatin; and heterochromatin. Orthologous to human TRIM28 (tripartite motif containing 28); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
[2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Aphidicolin results in increased phosphorylation of TRIM28 protein]
[2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one results in decreased activity of ATM protein] inhibits the reaction [Cisplatin results in increased phosphorylation of TRIM28 protein]
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of TRIM28 protein] more ...
Ascorbic Acid inhibits the reaction [Hydrogen Peroxide results in increased expression of TRIM28 protein] and Ascorbic Acid inhibits the reaction [potassium chromate(VI) results in increased expression of TRIM28 protein modified form]
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Hydrogen Peroxide results in increased phosphorylation of TRIM28 protein]] more ...