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Gene: Trim28 (tripartite motif-containing 28) Mus musculus
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Symbol: Trim28
Name: tripartite motif-containing 28
Description: Exhibits DNA binding activity; protein kinase activity; and transcription coactivator activity. Contributes to sequence-specific DNA binding activity. Involved in several processes, including DNA methylation involved in embryo development; negative regulation of single stranded viral RNA replication via double stranded DNA intermediate; and regulation of nucleobase-containing compound metabolic process. Localizes to the nucleus. Is expressed in several structures, including branchial arch; central nervous system; early conceptus; genitourinary system; and limb. Orthologous to human TRIM28 (tripartite motif containing 28); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 1,4-dichlorobenzene; 2,3,7,8-tetrachlorodibenzodioxine; aphidicolin.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408787; E3 SUMO-protein ligase TRIM28; KAP-1; KRAB-A-interacting protein; KRIP-1; MGC102100; MommeD9; RING-type E3 ubiquitin transferase TIF1-beta; TIF1-beta; Tif1b; Tif1beta; transcription intermediary factor 1-beta; transcriptional intermediary factor 1, beta; tripartite motif protein 28; tripartite motif-containing protein 28
Orthologs:
Homo sapiens (human) : TRIM28 (tripartite motif containing 28)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Trim28 (tripartite motif-containing 28)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim28 (tripartite motif containing 28)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM28 (tripartite motif containing 28)
Canis lupus familiaris (dog) : TRIM28 (tripartite motif containing 28)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim28 (tripartite motif containing 28)
Sus scrofa (pig) : TRIM28 (tripartite motif containing 28)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38713,024,152 - 13,031,032 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37713,609,501 - 13,616,381 (+)NCBIGRCm37mm9NCBIm37
MGSCv36711,924,340 - 11,931,208 (+)NCBImm8
Celera710,651,338 - 10,658,223 (+)NCBICelera
Cytogenetic Map7 A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Trim28
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736266
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-09-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.