Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TRAF5 mRNA | CTD | PMID:22079256 | 1,2-dichloroethane | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of TRAF5 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of TRAF5 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TRAF5 mRNA | CTD | PMID:22206623 | 17beta-estradiol | affects expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Estradiol affects the expression of TRAF5 mRNA | CTD | PMID:21826169 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Traf5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TRAF5 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of TRAF5 mRNA | CTD | PMID:15972635 more ... | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in increased expression of TRAF5 mRNA | CTD | PMID:25975270 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of TRAF5 mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | Traf5 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of TRAF5 promoter | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Traf5 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of TRAF5 mRNA | CTD | PMID:18648102 | acrylamide | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of TRAF5 mRNA | CTD | PMID:32763439 | aflatoxin B1 | decreases methylation | ISO | TRAF5 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TRAF5 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | increases methylation | ISO | TRAF5 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of TRAF5 intron | CTD | PMID:30157460 | all-trans-retinoic acid | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of TRAF5 mRNA | CTD | PMID:21934132 more ... | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of TRAF5 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TRAF5 mRNA | CTD | PMID:33212167 | arsane | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [Arsenic co-treated with Fluorides] results in decreased expression of TRAF5 mRNA | CTD | PMID:19962721 | arsenic atom | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [Arsenic co-treated with Fluorides] results in decreased expression of TRAF5 mRNA | CTD | PMID:19962721 | arsenous acid | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TRAF5 mRNA | CTD | PMID:17530438 | benzo[a]pyrene | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to TRAF5 promoter] | CTD | PMID:19654925 | benzo[a]pyrene | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of TRAF5 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | decreases methylation | ISO | TRAF5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TRAF5 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | TRAF5 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TRAF5 5' UTR and Benzo(a)pyrene affects the methylation of TRAF5 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20382639 | bisphenol A | affects expression | ISO | TRAF5 (Homo sapiens) | 6480464 | bisphenol A affects the expression of TRAF5 mRNA | CTD | PMID:21826169 | carbon nanotube | decreases expression | ISO | Traf5 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TRAF5 gene] | CTD | PMID:28238834 | ciguatoxin CTX1B | affects expression | ISO | Traf5 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of TRAF5 mRNA | CTD | PMID:18353800 | copper atom | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TRAF5 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of TRAF5 mRNA | CTD | PMID:20971185 | copper(II) chloride | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | cupric chloride results in increased expression of TRAF5 mRNA | CTD | PMID:17211630 | diarsenic trioxide | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of TRAF5 mRNA | CTD | PMID:17530438 | dibutyl phthalate | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of TRAF5 mRNA | CTD | PMID:17361019 and PMID:21266533 | epoxiconazole | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of TRAF5 mRNA | CTD | PMID:35436446 | ethanol | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in increased expression of TRAF5 mRNA | CTD | PMID:23378141 | ethanol | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Ethanol results in increased expression of TRAF5 mRNA | CTD | PMID:23378141 | fluoranthene | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of TRAF5 mRNA | CTD | PMID:28329830 | folic acid | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [Ethanol co-treated with Folic Acid] results in increased expression of TRAF5 mRNA | CTD | PMID:23378141 | folic acid | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of TRAF5 mRNA | CTD | PMID:22206623 | furosemide | affects expression | EXP | | 6480464 | Furosemide affects the expression of TRAF5 mRNA | CTD | PMID:17497460 | gallic acid | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Gallic Acid results in decreased expression of TRAF5 mRNA | CTD | PMID:34408198 | methyl methanesulfonate | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of TRAF5 mRNA | CTD | PMID:23649840 | methylphenidate | decreases expression | ISO | Traf5 (Mus musculus) | 6480464 | Methylphenidate results in decreased expression of TRAF5 mRNA | CTD | PMID:22470460 | N-methyl-4-phenylpyridinium | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of TRAF5 mRNA | CTD | PMID:24810058 | o-anisidine | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | 2-anisidine results in increased expression of TRAF5 mRNA | CTD | PMID:28089782 | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of TRAF5 mRNA | CTD | PMID:25729387 | ozone | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of TRAF5 mRNA | CTD | PMID:34911549 | p-menthan-3-ol | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Menthol results in decreased expression of TRAF5 mRNA | CTD | PMID:26760959 | paclitaxel | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Paclitaxel results in decreased expression of TRAF5 mRNA | CTD | PMID:15000894 | paracetamol | affects expression | ISO | Traf5 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TRAF5 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TRAF5 mRNA | CTD | PMID:26690555 | pentachlorophenol | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of TRAF5 mRNA | CTD | PMID:23892564 | pirinixic acid | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TRAF5 mRNA | CTD | PMID:19710929 | potassium chromate | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TRAF5 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TRAF5 mRNA | CTD | PMID:22079256 | raloxifene | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA | CTD | PMID:19059307 | sarin | increases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Sarin results in increased expression of TRAF5 mRNA | CTD | PMID:19522546 | succimer | multiple interactions | ISO | Traf5 (Mus musculus) | 6480464 | [Succimer binds to Magnetite Nanoparticles] which results in increased expression of TRAF5 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of TRAF5 mRNA | CTD | PMID:21641980 and PMID:26378955 | tamibarotene | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | tamibarotene results in decreased expression of TRAF5 mRNA | CTD | PMID:17229644 | tamoxifen | multiple interactions | ISO | TRAF5 (Homo sapiens) | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in increased expression of TRAF5 mRNA | CTD | PMID:19059307 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of TRAF5 mRNA | CTD | PMID:31150632 | thimerosal | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of TRAF5 mRNA | CTD | PMID:27188386 | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of TRAF5 mRNA | CTD | PMID:25729387 | valproic acid | decreases methylation | ISO | TRAF5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TRAF5 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | TRAF5 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of TRAF5 mRNA | CTD | PMID:28001369 | WIN 55212-2 | increases expression | ISO | Traf5 (Mus musculus) | 6480464 | (3R)-((2 more ... | CTD | PMID:12237329 | |