Gene: Psmb8 (proteasome 20S subunit beta 8) Rattus norvegicus
Analyze
Symbol:
Psmb8
Name:
proteasome 20S subunit beta 8
Description:
Predicted to have endopeptidase activity. Predicted to be involved in several processes, including fat cell differentiation; proteasomal protein catabolic process; and regulation of endopeptidase activity. Predicted to localize to cytoplasm; nucleus; and proteasome complex. Human ortholog(s) of this gene implicated in JMP syndrome. Orthologous to human PSMB8 (proteasome 20S subunit beta 8); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type:
protein-coding
RefSeq Status:
VALIDATED
Also known as:
large multifunctional protease 7; Lmp7; low molecular mass polypeptide 7; macropain subunit C13; MGC124945; multicatalytic endopeptidase complex subunit C13; proteasome (prosome macropain) subunit beta type 8 (low molecular mass polypeptide 7); proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7); proteasome (prosome, macropain) subunit, beta type, 8; proteasome component C13; proteasome subunit beta 8; proteasome subunit beta type-8; proteasome subunit beta-5i; proteosome (prosome macropain) subunit beta type 8 (large multifunctional protease 7); proteosome (prosome, macropain) subunit, beta type 8; Ring10
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PSMB8 (proteasome 20S subunit beta 8) HGNC
Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Psmb8 (proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)) HGNC
Treefam, OrthoMCL, NCBI, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Psmb8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PSMB8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PSMB8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Psmb8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PSMB8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
PSMB8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Psmb8 (proteasome 20S subunit beta 8) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
PSMB8 (proteasome 20S subunit beta 8)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Mus musculus (house mouse):
Psmb8 (proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7))
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Danio rerio (zebrafish):
psmb8a (proteasome subunit beta 8A)
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Saccharomyces cerevisiae (baker's yeast):
PRE2
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
Prosbeta5
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
Prosbeta5R1
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Drosophila melanogaster (fruit fly):
Prosbeta5R2
Alliance
DIOPT (Ensembl Compara|Hieranoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|TreeFam)
Caenorhabditis elegans (roundworm):
pbs-5
Alliance
DIOPT (Ensembl Compara|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 20 3,990,809 - 3,993,772 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 20 3,990,613 - 3,993,769 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 20 7,275,040 - 7,276,378 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Rnor_5.0 20 6,070,355 - 6,073,317 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 20 4,786,260 - 4,789,223 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 20 4,786,490 - 4,789,389 (-) NCBI Celera 20 6,253,214 - 6,256,177 (-) NCBI Celera Cytogenetic Map 20 p12 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:21881205 , PMID:8495043 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:21852578 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:25741868 , PMID:28492532 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:24033266 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:25741868 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:21953331 , PMID:26524591 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:26524591 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: Proteasome-associated autoinflammatory syndrome 1 ClinVar PMID:28492532 JMP syndrome ISO RGD:731895 8554872 ClinVar Annotator: match by term: PROTEASOME-ASSOCIATED AUTOINFLAMMATORY SYNDROME 1, DIGENIC ClinVar PMID:20159315 more ...
Imported Annotations - CTD
Experimental Liver Cirrhosis ISO RGD:731895 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:25380136 Imported Annotations - Genetic Association Database
type 1 diabetes mellitus ISO RGD:731895 1331525 GAD Imported Annotations - OMIM
JMP syndrome ISO RGD:731895 7240710 OMIM
1,1-dichloroethene increases expression ISO RGD:736194 6480464 vinylidene chloride results in increased expression of PSMB8 mRNA CTD PMID:26682919 1,2-dimethylhydrazine multiple interactions ISO RGD:736194 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PSMB8 mRNA CTD PMID:22206623 1,3-dinitrobenzene affects expression EXP 6480464 3-dinitrobenzene affects the expression of PSMB8 mRNA CTD PMID:16988215 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of PSMB8 mRNA CTD PMID:17351261 , PMID:17557909 17beta-estradiol multiple interactions ISO RGD:731895 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PSMB8 mRNA, [Estradiol co-treated with TGFB1 protein] results in decreased expression of PSMB8 mRNA CTD PMID:19619570 , PMID:30165855 17beta-estradiol increases expression ISO RGD:736194 6480464 Estradiol results in increased expression of PSMB8 mRNA CTD PMID:15289156 17beta-estradiol increases expression ISO RGD:731895 6480464 Estradiol results in increased expression of PSMB8 mRNA CTD PMID:19619570 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:736194 6480464 2 more ... CTD PMID:30294300 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:731895 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of PSMB8 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of PSMB8 mRNA CTD PMID:16054898 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of PSMB8 mRNA] CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:736194 6480464 Tetrachlorodibenzodioxin results in increased expression of PSMB8 mRNA CTD PMID:19933214 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:731895 6480464 Tetrachlorodibenzodioxin results in decreased expression of PSMB8 mRNA CTD PMID:19619570 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:731895 6480464 Tetrachlorodibenzodioxin results in increased expression of PSMB8 mRNA CTD PMID:20106945 2,4-dinitrobenzenesulfonic acid decreases expression ISO RGD:736194 6480464 2, 4-dinitrobenzenesulfonic acid results in decreased expression of PSMB8 mRNA CTD PMID:30116771 2-hydroxypropanoic acid decreases expression ISO RGD:731895 6480464 Lactic Acid results in decreased expression of PSMB8 mRNA CTD PMID:30851411 2-nitrofluorene increases expression EXP 6480464 2-nitrofluorene results in increased expression of PSMB8 mRNA CTD PMID:14600272 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:20959002 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:23196670 3,4-dihydrocoumarin decreases expression ISO RGD:736194 6480464 3, 4-dihydrocoumarin results in decreased expression of PSMB8 mRNA CTD PMID:22016648 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:736194 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of PSMB8 mRNA CTD PMID:20188158 3-methylcholanthrene increases expression ISO RGD:736194 6480464 Methylcholanthrene results in increased expression of PSMB8 mRNA CTD PMID:29554273 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4, 4'-diaminodiphenylmethane results in increased expression of PSMB8 mRNA CTD PMID:25380136 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP 6480464 Oxazolone results in increased expression of PSMB8 mRNA CTD PMID:21893156 4-hydroxyphenyl retinamide increases expression ISO RGD:736194 6480464 Fenretinide results in increased expression of PSMB8 mRNA CTD PMID:28973697 acetamide increases expression EXP 6480464 acetamide results in increased expression of PSMB8 mRNA CTD PMID:31881176 all-trans-retinoic acid multiple interactions ISO RGD:731895 6480464 [Tretinoin co-treated with arsenic trioxide] results in increased expression of PSMB8 mRNA CTD PMID:15894607 all-trans-retinoic acid increases expression ISO RGD:731895 6480464 Tretinoin results in increased expression of PSMB8 mRNA CTD PMID:15894607 more ... ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of PSMB8 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:731895 6480464 Antirheumatic Agents results in decreased expression of PSMB8 mRNA CTD PMID:24449571 arsenous acid multiple interactions ISO RGD:731895 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PSMB8 mRNA CTD PMID:15894607 arsenous acid decreases expression ISO RGD:731895 6480464 Arsenic Trioxide results in decreased expression of PSMB8 mRNA, Arsenic Trioxide results in decreased expression of PSMB8 protein CTD PMID:15725085 more ... atrazine affects methylation EXP 6480464 Atrazine affects the methylation of PSMB8 gene CTD PMID:28931070 benzo[a]pyrene decreases expression ISO RGD:736194 6480464 Benzo(a)pyrene results in decreased expression of PSMB8 mRNA CTD PMID:21569818 benzo[a]pyrene increases expression ISO RGD:736194 6480464 Benzo(a)pyrene results in increased expression of PSMB8 mRNA CTD PMID:22228805 benzo[a]pyrene multiple interactions ISO RGD:736194 6480464 AHR protein affects the reaction [Benzo(a)pyrene affects the expression of PSMB8 mRNA] CTD PMID:22228805 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PSMB8 mRNA CTD PMID:25181051 , PMID:30816183 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of PSMB8 gene CTD PMID:28505145 bisphenol F increases expression ISO RGD:736194 6480464 bisphenol F results in increased expression of PSMB8 mRNA CTD PMID:30951980 buspirone decreases expression EXP 6480464 Buspirone results in decreased expression of PSMB8 mRNA CTD PMID:24136188 C60 fullerene decreases expression EXP 6480464 fullerene C60 results in decreased expression of PSMB8 mRNA CTD PMID:19167457 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of PSMB8 promoter CTD PMID:22457795 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of PSMB8 mRNA CTD PMID:25993096 carbon nanotube increases expression ISO RGD:736194 6480464 Nanotubes, Carbon analog results in increased expression of PSMB8 mRNA, Nanotubes, Carbon results in increased expression of PSMB8 mRNA CTD PMID:25554681 chloroprene decreases expression ISO RGD:736194 6480464 Chloroprene results in decreased expression of PSMB8 mRNA CTD PMID:23125180 chromium(6+) affects expression ISO RGD:736194 6480464 chromium hexavalent ion affects the expression of PSMB8 mRNA CTD PMID:28472532 cisplatin multiple interactions ISO RGD:731895 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of PSMB8 mRNA CTD PMID:27392435 cisplatin increases expression ISO RGD:731895 6480464 Cisplatin results in increased expression of PSMB8 mRNA CTD PMID:27392435 clofibrate decreases expression ISO RGD:736194 6480464 Clofibrate results in decreased expression of PSMB8 mRNA CTD PMID:23811191 copper(II) sulfate decreases expression ISO RGD:731895 6480464 Copper Sulfate results in decreased expression of PSMB8 mRNA CTD PMID:19549813 crocidolite asbestos affects methylation ISO RGD:731895 6480464 Asbestos, Crocidolite affects the methylation of PSMB8 5' UTR, Asbestos, Crocidolite affects the methylation of PSMB8 exon CTD PMID:29523930 cyclosporin A decreases expression ISO RGD:731895 6480464 Cyclosporine results in decreased expression of PSMB8 mRNA CTD PMID:25562108 deoxynivalenol decreases expression ISO RGD:736194 6480464 deoxynivalenol results in decreased expression of PSMB8 mRNA CTD PMID:15371230 dextran sulfate increases expression ISO RGD:736194 6480464 Dextran Sulfate results in increased expression of PSMB8 mRNA CTD PMID:23894361 diarsenic trioxide multiple interactions ISO RGD:731895 6480464 [Tretinoin co-treated with Arsenic Trioxide] results in increased expression of PSMB8 mRNA CTD PMID:15894607 diarsenic trioxide decreases expression ISO RGD:731895 6480464 Arsenic Trioxide results in decreased expression of PSMB8 mRNA, Arsenic Trioxide results in decreased expression of PSMB8 protein CTD PMID:15725085 more ... dichlorine multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of PSMB8 mRNA CTD PMID:18636392 diethylstilbestrol increases expression ISO RGD:736194 6480464 Diethylstilbestrol results in increased expression of PSMB8 mRNA CTD PMID:15289156 dorsomorphin multiple interactions ISO RGD:731895 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin decreases expression ISO RGD:736194 6480464 Doxorubicin results in decreased expression of PSMB8 mRNA, Doxorubicin results in decreased expression of PSMB8 protein CTD PMID:25896364 doxorubicin increases expression ISO RGD:736194 6480464 Doxorubicin results in increased expression of PSMB8 mRNA CTD PMID:27155237 doxorubicin multiple interactions ISO RGD:736194 6480464 Doxorubicin inhibits the reaction [IFNG protein results in increased expression of PSMB8 mRNA] more ... CTD PMID:25896364 , PMID:27155237 entinostat increases expression ISO RGD:731895 6480464 entinostat results in increased expression of PSMB8 mRNA CTD PMID:27188386 flavonoids increases expression EXP 6480464 Flavonoids results in increased expression of PSMB8 mRNA CTD PMID:18035473 folic acid multiple interactions ISO RGD:736194 6480464 [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of PSMB8 mRNA CTD PMID:22206623 Genipin multiple interactions ISO RGD:736194 6480464 genipin inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB8 mRNA] CTD PMID:22687549 genistein increases expression ISO RGD:736194 6480464 Genistein results in increased expression of PSMB8 mRNA CTD PMID:15289156 genistein multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of PSMB8 mRNA CTD PMID:21782745 genistein decreases expression EXP 6480464 Genistein results in decreased expression of PSMB8 mRNA CTD PMID:21782745 gentamycin increases expression EXP 6480464 Gentamicins results in increased expression of PSMB8 mRNA CTD PMID:22061828 ionomycin multiple interactions ISO RGD:736194 6480464 [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA] more ... CTD PMID:22398747 lactacystin multiple interactions ISO RGD:736194 6480464 [PSMB8 protein co-treated with PSMB10 protein] affects the susceptibility to lactacystin CTD PMID:22398747 leflunomide decreases expression EXP 6480464 leflunomide results in decreased expression of PSMB8 mRNA CTD PMID:24136188 lipopolysaccharide multiple interactions ISO RGD:736194 6480464 genipin inhibits the reaction [Lipopolysaccharides results in increased expression of PSMB8 mRNA] CTD PMID:22687549 lipopolysaccharide increases expression ISO RGD:736194 6480464 Lipopolysaccharides results in increased expression of PSMB8 mRNA CTD PMID:22687549 , PMID:27339419 mercury dibromide decreases expression ISO RGD:731895 6480464 mercuric bromide results in decreased expression of PSMB8 mRNA CTD PMID:26272509 mercury dibromide multiple interactions ISO RGD:731895 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PSMB8 mRNA CTD PMID:27188386 methotrexate increases expression ISO RGD:731895 6480464 Methotrexate results in increased expression of PSMB8 mRNA CTD PMID:21678067 methoxychlor multiple interactions EXP 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of PSMB8 mRNA CTD PMID:21782745 methoxychlor decreases expression EXP 6480464 Methoxychlor results in decreased expression of PSMB8 mRNA CTD PMID:21782745 methylmercury chloride decreases expression ISO RGD:736194 6480464 methylmercuric chloride results in decreased expression of PSMB8 mRNA CTD PMID:20061341 N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of PSMB8 mRNA CTD PMID:25380136 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of PSMB8 mRNA CTD PMID:24136188 nickel atom increases expression ISO RGD:731895 6480464 Nickel results in increased expression of PSMB8 mRNA CTD PMID:24768652 , PMID:25583101 nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of PSMB8 mRNA CTD PMID:22110744 nickel sulfate increases expression ISO RGD:731895 6480464 nickel sulfate results in increased expression of PSMB8 mRNA CTD PMID:22714537 nimesulide decreases expression EXP 6480464 nimesulide results in decreased expression of PSMB8 mRNA CTD PMID:24136188 ozone multiple interactions EXP 6480464 [Ozone co-treated with Chlorine] results in decreased expression of PSMB8 mRNA CTD PMID:18636392 p-chloromercuribenzoic acid decreases expression ISO RGD:731895 6480464 p-Chloromercuribenzoic Acid results in decreased expression of PSMB8 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions ISO RGD:731895 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PSMB8 mRNA CTD PMID:27188386 paracetamol decreases expression ISO RGD:731895 6480464 Acetaminophen results in decreased expression of PSMB8 mRNA CTD PMID:21420995 paracetamol affects response to substance ISO RGD:731895 6480464 PSMB8 gene polymorphism affects the susceptibility to Acetaminophen CTD PMID:26104854 paracetamol increases expression ISO RGD:731895 6480464 Acetaminophen results in increased expression of PSMB8 mRNA CTD PMID:22230336 pentachlorophenol increases expression ISO RGD:736194 6480464 Pentachlorophenol results in increased expression of PSMB8 mRNA CTD PMID:23892564 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:736194 6480464 perfluorooctane sulfonic acid results in decreased expression of PSMB8 mRNA, perfluorooctane sulfonic acid results in decreased expression of PSMB8 protein CTD PMID:20936131 , PMID:26178269 perfluorooctanoic acid multiple interactions ISO RGD:736194 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of PSMB8 mRNA] CTD PMID:18467677 perfluorooctanoic acid decreases expression ISO RGD:736194 6480464 perfluorooctanoic acid results in decreased expression of PSMB8 mRNA CTD PMID:18467677 , PMID:20936131 phenformin increases expression EXP 6480464 Phenformin results in increased expression of PSMB8 mRNA CTD PMID:31324951 phenylmercury acetate decreases expression ISO RGD:731895 6480464 Phenylmercuric Acetate results in decreased expression of PSMB8 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:731895 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of PSMB8 mRNA CTD PMID:27188386 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:736194 6480464 [PSMB8 protein co-treated with PSMB10 protein] affects the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of GATA3 mRNA] more ... CTD PMID:22398747 picrotoxin increases expression EXP 6480464 Picrotoxin results in increased expression of PSMB8 mRNA CTD PMID:15170462 pirinixic acid multiple interactions ISO RGD:736194 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of PSMB8 mRNA more ... CTD PMID:17950772 more ... pirinixic acid decreases expression ISO RGD:736194 6480464 pirinixic acid results in decreased expression of PSMB8 mRNA CTD PMID:15375163 more ... pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of PSMB8 mRNA CTD PMID:19162173 , PMID:21318169 potassium chromate decreases expression ISO RGD:731895 6480464 potassium chromate(VI) results in decreased expression of PSMB8 mRNA CTD PMID:22714537 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:736194 6480464 Pregnenolone Carbonitrile results in decreased expression of PSMB8 mRNA CTD PMID:28903501 rac-lactic acid decreases expression ISO RGD:731895 6480464 Lactic Acid results in decreased expression of PSMB8 mRNA CTD PMID:30851411 resveratrol decreases expression ISO RGD:736194 6480464 resveratrol results in decreased expression of PSMB8 protein CTD PMID:25505154 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PSMB8 mRNA CTD PMID:28374803 S-adenosyl-L-methioninate increases expression ISO RGD:736194 6480464 S-Adenosylmethionine results in increased expression of PSMB8 mRNA CTD PMID:18098314 S-adenosyl-L-methionine increases expression ISO RGD:736194 6480464 S-Adenosylmethionine results in increased expression of PSMB8 mRNA CTD PMID:18098314 SB 431542 multiple interactions ISO RGD:731895 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 sibutramine decreases expression ISO RGD:731895 6480464 sibutramine results in decreased expression of PSMB8 protein CTD PMID:27838152 silicon dioxide increases expression ISO RGD:736194 6480464 Silicon Dioxide results in increased expression of PSMB8 mRNA CTD PMID:29341224 sodium arsenate decreases expression ISO RGD:731895 6480464 sodium arsenate results in decreased expression of PSMB8 mRNA CTD PMID:12727804 sodium arsenite decreases expression ISO RGD:731895 6480464 sodium arsenite results in decreased expression of PSMB8 mRNA CTD PMID:12727804 sodium arsenite increases expression ISO RGD:736194 6480464 sodium arsenite results in increased expression of PSMB8 mRNA CTD PMID:17350061 Soman increases expression EXP 6480464 Soman results in increased expression of PSMB8 mRNA CTD PMID:19281266 sulforaphane decreases expression ISO RGD:731895 6480464 sulforafan results in decreased expression of PSMB8 mRNA CTD PMID:31838189 tetrachloromethane affects expression ISO RGD:736194 6480464 Carbon Tetrachloride affects the expression of PSMB8 mRNA CTD PMID:17484886 tetrachloromethane increases expression ISO RGD:736194 6480464 Carbon Tetrachloride results in increased expression of PSMB8 mRNA CTD PMID:31919559 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of PSMB8 mRNA CTD PMID:31150632 theophylline affects expression EXP 6480464 Theophylline affects the expression of PSMB8 mRNA CTD PMID:16988215 thioacetamide decreases expression EXP 6480464 Thioacetamide results in decreased expression of PSMB8 mRNA CTD PMID:23411599 titanium dioxide increases expression ISO RGD:736194 6480464 titanium dioxide results in increased expression of PSMB8 mRNA CTD PMID:23409001 , PMID:23557971 trichloroethene increases methylation EXP 6480464 Trichloroethylene results in increased methylation of PSMB8 gene CTD PMID:27618143 triclosan increases expression ISO RGD:731895 6480464 Triclosan results in increased expression of PSMB8 mRNA CTD PMID:30510588 trimellitic anhydride increases expression EXP 6480464 trimellitic anhydride results in increased expression of PSMB8 mRNA CTD PMID:21893156 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of PSMB8 mRNA CTD PMID:21318169 valproic acid decreases expression ISO RGD:731895 6480464 Valproic Acid results in decreased expression of PSMB8 mRNA CTD PMID:28001369 , PMID:29154799 valproic acid affects expression ISO RGD:731895 6480464 Valproic Acid affects the expression of PSMB8 mRNA CTD PMID:25979313 vancomycin decreases expression ISO RGD:736194 6480464 Vancomycin results in decreased expression of PSMB8 mRNA CTD PMID:18930951 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of PSMB8 mRNA CTD PMID:19015723 vinclozolin increases expression EXP 6480464 vinclozolin results in increased expression of PSMB8 mRNA CTD PMID:22570695 , PMID:23034163
Gene-Chemical Interaction Annotations
