Cdc14b (cell division cycle 14B) - Rat Genome Database

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Gene: Cdc14b (cell division cycle 14B) Rattus norvegicus
Analyze
Symbol: Cdc14b
Name: cell division cycle 14B
RGD ID: 1311163
Description: Predicted to enable protein serine/threonine phosphatase activity and protein tyrosine phosphatase activity. Predicted to be involved in several processes, including positive regulation of ubiquitin protein ligase activity; protein dephosphorylation; and regulation of cell cycle process. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleolus. Orthologous to human CDC14B (cell division cycle 14B); PARTICIPATES IN RNA polymerase II transcription pathway; cell cycle pathway, mitotic; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CDC14 cell division cycle 14 homolog B; CDC14 cell division cycle 14 homolog B (S. cerevisiae); dual specificity protein phosphatase CDC14B; LOC361195
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.217844,731 - 934,787 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl171,703,943 - 1,797,750 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0171,709,703 - 1,797,732 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0171,699,259 - 1,787,005 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,371,204 - 6,454,460 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1176,397,503 - 6,451,948 (+)NCBI
Celera171,589,728 - 1,671,876 (-)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(RS)-coclaurine  (ISO)
(RS)-norcoclaurine  (ISO)
(S)-coclaurine  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
4-hydroxyphenyl retinamide  (ISO)
aflatoxin B1  (ISO)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP)
butanal  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calyculin a  (ISO)
carbon nanotube  (ISO)
chrysene  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
coumestrol  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
disodium selenite  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
endosulfan  (EXP)
folic acid  (ISO)
GW 3965  (ISO)
isotretinoin  (ISO)
leflunomide  (ISO)
melphalan  (ISO)
menadione  (ISO)
mercury dibromide  (ISO)
methotrexate  (ISO)
methylmercury chloride  (ISO)
methylseleninic acid  (ISO)
p-chloromercuribenzoic acid  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
pentachlorophenol  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propiconazole  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
trichostatin A  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)
yohimbine  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:9367992   PMID:18662541  


Genomics

Comparative Map Data
Cdc14b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.217844,731 - 934,787 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl171,703,943 - 1,797,750 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0171,709,703 - 1,797,732 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0171,699,259 - 1,787,005 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,371,204 - 6,454,460 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1176,397,503 - 6,451,948 (+)NCBI
Celera171,589,728 - 1,671,876 (-)NCBICelera
Cytogenetic Map17p14NCBI
CDC14B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl996,490,241 - 96,619,843 (-)EnsemblGRCh38hg38GRCh38
GRCh38996,492,743 - 96,619,843 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37999,262,390 - 99,382,125 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,302,216 - 98,421,933 (-)NCBINCBI36hg18NCBI36
Build 34996,332,077 - 96,461,667NCBI
Celera969,703,970 - 69,823,685 (-)NCBI
Cytogenetic Map9q22.32-q22.33NCBI
HuRef968,873,293 - 68,940,865 (-)NCBIHuRef
CHM1_1999,409,222 - 99,528,933 (-)NCBICHM1_1
Cdc14b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,337,085 - 64,423,670 (-)NCBIGRCm39mm39
GRCm39 Ensembl1364,337,082 - 64,423,104 (-)Ensembl
GRCm381364,192,545 - 64,274,988 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,189,268 - 64,275,290 (-)EnsemblGRCm38mm10GRCm38
MGSCv371364,293,853 - 64,376,296 (-)NCBIGRCm37mm9NCBIm37
MGSCv361364,204,559 - 64,284,140 (-)NCBImm8
Celera1365,855,813 - 65,939,623 (-)NCBICelera
Cytogenetic Map13B3NCBI
Cdc14b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542223,303,250 - 23,322,493 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542223,303,472 - 23,445,785 (+)NCBIChiLan1.0ChiLan1.0
CDC14B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1995,717,715 - 95,784,114 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0967,596,037 - 67,715,668 (-)NCBIMhudiblu_PPA_v0panPan3
CDC14B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,232,932 - 70,335,950 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,232,947 - 70,335,943 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha170,996,105 - 71,099,112 (+)NCBI
ROS_Cfam_1.0170,532,035 - 70,635,025 (+)NCBI
UMICH_Zoey_3.1170,345,666 - 70,448,290 (+)NCBI
UNSW_CanFamBas_1.0170,108,595 - 70,211,414 (+)NCBI
UU_Cfam_GSD_1.0170,819,771 - 70,922,450 (+)NCBI
Cdc14b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049446,210,303 - 6,348,193 (-)NCBI
SpeTri2.0NW_004936487430,449 - 482,517 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC14B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11025,471,976 - 25,590,022 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21029,550,676 - 29,666,345 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CDC14B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112106,520,152 - 106,645,468 (+)NCBI
ChlSab1.1 Ensembl12106,572,015 - 106,633,316 (+)Ensembl
Vero_WHO_p1.0NW_02366603894,918,039 - 95,044,036 (+)NCBI
Cdc14b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475317,941,852 - 18,040,542 (+)NCBI

Position Markers
D17Got231  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217864,552 - 864,835 (-)MAPPERmRatBN7.2
Rnor_6.0171,777,624 - 1,777,906NCBIRnor6.0
Rnor_5.0171,767,180 - 1,767,462UniSTSRnor5.0
RGSC_v3.4176,390,915 - 6,391,197UniSTSRGSC3.4
Celera171,651,890 - 1,652,172UniSTS
Cytogenetic Map17p14UniSTS
D17Got227  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217864,699 - 864,831 (-)MAPPERmRatBN7.2
Rnor_6.0171,777,628 - 1,777,759NCBIRnor6.0
Rnor_5.0171,767,184 - 1,767,315UniSTSRnor5.0
RGSC_v3.4176,391,062 - 6,391,193UniSTSRGSC3.4
Celera171,651,894 - 1,652,025UniSTS
Cytogenetic Map17p14UniSTS
BE103190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217869,293 - 869,464 (-)MAPPERmRatBN7.2
Rnor_6.0171,772,994 - 1,773,164NCBIRnor6.0
Rnor_5.0171,762,550 - 1,762,720UniSTSRnor5.0
RGSC_v3.4176,395,656 - 6,395,826UniSTSRGSC3.4
Celera171,647,261 - 1,647,431UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS
RH139701  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.217907,016 - 907,551 (-)MAPPERmRatBN7.2
Rnor_6.0171,729,644 - 1,730,178NCBIRnor6.0
Rnor_5.0171,719,200 - 1,719,734UniSTSRnor5.0
RGSC_v3.4176,433,985 - 6,434,519UniSTSRGSC3.4
Celera171,609,669 - 1,610,203UniSTS
RH 3.4 Map1716.0UniSTS
Cytogenetic Map17p14UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17124787908Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17132230361Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17133303755Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17138243814Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17163676140Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17173413148Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17173413148Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)1751977023422380Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1751977036283402Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:489
Count of miRNA genes:257
Interacting mature miRNAs:330
Transcripts:ENSRNOT00000033017
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 8 18 10 9 10 6 35 38 9
Low 3 35 39 31 10 31 8 11 68 3 2 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095828 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095833 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095834 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095844 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039095846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495291 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_005495292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000033017   ⟹   ENSRNOP00000038515
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl171,709,703 - 1,797,732 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079742   ⟹   ENSRNOP00000074320
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl171,703,943 - 1,797,750 (-)Ensembl
RefSeq Acc Id: NM_001108404   ⟹   NP_001101874
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,731 - 927,479 (+)NCBI
Rnor_6.0171,709,703 - 1,797,732 (-)NCBI
Rnor_5.0171,699,259 - 1,787,005 (-)NCBI
RGSC_v3.4176,371,204 - 6,454,460 (+)RGD
Celera171,589,728 - 1,671,876 (-)RGD
Sequence:
RefSeq Acc Id: XM_039095828   ⟹   XP_038951756
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095829   ⟹   XP_038951757
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 934,787 (+)NCBI
RefSeq Acc Id: XM_039095830   ⟹   XP_038951758
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 933,237 (+)NCBI
RefSeq Acc Id: XM_039095831   ⟹   XP_038951759
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095833   ⟹   XP_038951761
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 921,609 (+)NCBI
RefSeq Acc Id: XM_039095834   ⟹   XP_038951762
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,951 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095835   ⟹   XP_038951763
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,944 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095836   ⟹   XP_038951764
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095837   ⟹   XP_038951765
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 932,865 (+)NCBI
RefSeq Acc Id: XM_039095838   ⟹   XP_038951766
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095839   ⟹   XP_038951767
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,952 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095840   ⟹   XP_038951768
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095841   ⟹   XP_038951769
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 934,787 (+)NCBI
RefSeq Acc Id: XM_039095842   ⟹   XP_038951770
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,953 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095843   ⟹   XP_038951771
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217871,243 - 929,861 (+)NCBI
RefSeq Acc Id: XM_039095844   ⟹   XP_038951772
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 907,730 (+)NCBI
RefSeq Acc Id: XM_039095845   ⟹   XP_038951773
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 907,730 (+)NCBI
RefSeq Acc Id: XM_039095846   ⟹   XP_038951774
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217898,437 - 929,861 (+)NCBI
RefSeq Acc Id: XR_005495291
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 929,861 (+)NCBI
RefSeq Acc Id: XR_005495292
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.217844,881 - 912,901 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001101874   ⟸   NM_001108404
- UniProtKB: F1M567 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074320   ⟸   ENSRNOT00000079742
RefSeq Acc Id: ENSRNOP00000038515   ⟸   ENSRNOT00000033017
RefSeq Acc Id: XP_038951757   ⟸   XM_039095829
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951769   ⟸   XM_039095841
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038951758   ⟸   XM_039095830
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038951765   ⟸   XM_039095837
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038951766   ⟸   XM_039095838
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038951759   ⟸   XM_039095831
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038951756   ⟸   XM_039095828
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951764   ⟸   XM_039095836
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038951768   ⟸   XM_039095840
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038951761   ⟸   XM_039095833
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038951772   ⟸   XM_039095844
- Peptide Label: isoform X14
RefSeq Acc Id: XP_038951773   ⟸   XM_039095845
- Peptide Label: isoform X15
RefSeq Acc Id: XP_038951763   ⟸   XM_039095835
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951762   ⟸   XM_039095834
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038951767   ⟸   XM_039095839
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038951770   ⟸   XM_039095842
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038951771   ⟸   XM_039095843
- Peptide Label: isoform X13
RefSeq Acc Id: XP_038951774   ⟸   XM_039095846
- Peptide Label: isoform X16
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700269
Promoter ID:EPDNEW_R10786
Type:multiple initiation site
Name:Cdc14b_1
Description:cell division cycle 14B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0171,797,777 - 1,797,837EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311163 AgrOrtholog
Ensembl Genes ENSRNOG00000018999 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000038515 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000074320 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000033017 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000079742 UniProtKB/TrEMBL
Gene3D-CATH 3.90.190.10 UniProtKB/TrEMBL
InterPro CDC14_C UniProtKB/TrEMBL
  DSPn UniProtKB/TrEMBL
  Dual-sp_phosphatase_subgr_cat UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  Tyr/Dual-specificity_Pase UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
KEGG Report rno:361195 UniProtKB/TrEMBL
NCBI Gene 361195 ENTREZGENE
Pfam DSPn UniProtKB/TrEMBL
PhenoGen Cdc14b PhenoGen
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_DUAL UniProtKB/TrEMBL
SMART DSPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP SSF52799 UniProtKB/TrEMBL
UniProt A0A0G2K7S1_RAT UniProtKB/TrEMBL
  F1M567 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-23 Cdc14b  cell division cycle 14B  Cdc14b  CDC14 cell division cycle 14 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Cdc14b  CDC14 cell division cycle 14 homolog B (S. cerevisiae)   Cdc14b_predicted  CDC14 cell division cycle 14 homolog B (S. cerevisiae) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Cdc14b_predicted  CDC14 cell division cycle 14 homolog B (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED