Ube2v2 (ubiquitin conjugating enzyme E2 V2) - Rat Genome Database

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Gene: Ube2v2 (ubiquitin conjugating enzyme E2 V2) Rattus norvegicus
Analyze
Symbol: Ube2v2
Name: ubiquitin conjugating enzyme E2 V2
RGD ID: 727838
Description: Involved in negative regulation of neuron apoptotic process; positive regulation of cellular component organization; and positive regulation of nitrogen compound metabolic process. Predicted to localize to UBC13-MMS2 complex and nucleoplasm. Orthologous to human UBE2V2 (ubiquitin conjugating enzyme E2 V2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC105268; MMS2; ubiquitin-conjugating enzyme E2 variant 2; ubiquitin-conjugating enzyme E2v2; ubiquitin-conjugating enzyme variant MMS2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21185,304,528 - 85,338,430 (+)NCBI
Rnor_6.0 Ensembl1189,557,273 - 89,591,175 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01189,557,273 - 89,591,175 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01192,611,596 - 92,645,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,215,842 - 87,249,726 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11187,256,441 - 87,290,323 (+)NCBI
Celera1184,044,758 - 84,078,508 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IBA,ISO)
UBC13-MMS2 complex  (ISO)

Molecular Function

References

Additional References at PubMed
PMID:11406273   PMID:12477932   PMID:14406273   PMID:15489334   PMID:16129784   PMID:17349954   PMID:23376485   PMID:23533145  


Genomics

Comparative Map Data
Ube2v2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21185,304,528 - 85,338,430 (+)NCBI
Rnor_6.0 Ensembl1189,557,273 - 89,591,175 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01189,557,273 - 89,591,175 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01192,611,596 - 92,645,498 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,215,842 - 87,249,726 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11187,256,441 - 87,290,323 (+)NCBI
Celera1184,044,758 - 84,078,508 (+)NCBICelera
Cytogenetic Map11q23NCBI
UBE2V2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl848,008,415 - 48,064,708 (+)EnsemblGRCh38hg38GRCh38
GRCh38847,997,527 - 48,064,708 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37848,920,991 - 48,977,268 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36849,083,548 - 49,137,007 (+)NCBINCBI36hg18NCBI36
Build 34849,083,547 - 49,137,005NCBI
Celera844,906,250 - 44,959,689 (+)NCBI
Cytogenetic Map8q11.21NCBI
HuRef844,383,343 - 44,436,762 (+)NCBIHuRef
CHM1_1848,973,288 - 49,026,765 (+)NCBICHM1_1
Ube2v2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391615,368,850 - 15,412,382 (-)NCBIGRCm39mm39
GRCm39 Ensembl1615,369,941 - 15,413,637 (-)Ensembl
GRCm381615,550,986 - 15,594,518 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1615,552,077 - 15,595,773 (-)EnsemblGRCm38mm10GRCm38
MGSCv371615,551,079 - 15,594,611 (-)NCBIGRCm37mm9NCBIm37
MGSCv361615,466,261 - 15,508,079 (-)NCBImm8
Celera1616,127,322 - 16,170,926 (-)NCBICelera
Cytogenetic Map16A1- A2NCBI
Ube2v2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554547,951,876 - 7,998,686 (+)NCBIChiLan1.0ChiLan1.0
UBE2V2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1841,856,429 - 41,878,320 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl841,856,429 - 41,878,320 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0844,435,496 - 44,488,517 (+)NCBIMhudiblu_PPA_v0panPan3
UBE2V2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.129307,502 - 359,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl29307,525 - 357,962 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha29732,935 - 782,909 (+)NCBI
ROS_Cfam_1.029306,095 - 357,464 (+)NCBI
UMICH_Zoey_3.129303,991 - 354,158 (+)NCBI
UNSW_CanFamBas_1.029498,811 - 548,826 (+)NCBI
UU_Cfam_GSD_1.029567,077 - 617,090 (+)NCBI
Ube2v2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530379,448,058 - 79,481,052 (-)NCBI
SpeTri2.0NW_0049365904,637,858 - 4,670,789 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
UBE2V2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl479,419,358 - 79,652,471 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1479,621,343 - 79,652,502 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
UBE2V2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1844,167,214 - 44,218,074 (+)NCBI
Ube2v2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247357,431,955 - 7,464,698 (-)NCBI

Position Markers
BE108164  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21185,321,228 - 85,322,091 (+)MAPPER
mRatBN7.21185,321,936 - 85,322,091 (+)MAPPER
Rnor_6.01189,574,682 - 89,574,836NCBIRnor6.0
Rnor_6.01189,573,974 - 89,574,836NCBIRnor6.0
Rnor_5.01192,629,005 - 92,629,159UniSTSRnor5.0
Rnor_5.01192,628,297 - 92,629,159UniSTSRnor5.0
RGSC_v3.41187,232,525 - 87,233,387UniSTSRGSC3.4
RGSC_v3.41187,233,233 - 87,233,387UniSTSRGSC3.4
Celera1184,062,060 - 84,062,213UniSTS
Celera1184,061,352 - 84,062,213UniSTS
Cytogenetic Map11q23UniSTS
RH136981  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21185,336,112 - 85,336,318 (+)MAPPER
mRatBN7.21861,343,763 - 61,343,969 (+)MAPPER
Rnor_6.01189,588,858 - 89,589,063NCBIRnor6.0
Rnor_6.01863,541,878 - 63,542,086NCBIRnor6.0
Rnor_5.01862,721,164 - 62,721,372UniSTSRnor5.0
Rnor_5.01192,643,181 - 92,643,386UniSTSRnor5.0
RGSC_v3.41187,247,409 - 87,247,614UniSTSRGSC3.4
RGSC_v3.41864,323,041 - 64,323,249UniSTSRGSC3.4
Celera1859,447,263 - 59,447,468UniSTS
Celera1184,076,197 - 84,076,402UniSTS
Cytogenetic Map11q23UniSTS
RH141710  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21185,336,822 - 85,337,005 (+)MAPPER
Rnor_6.01189,589,568 - 89,589,750NCBIRnor6.0
Rnor_5.01192,643,891 - 92,644,073UniSTSRnor5.0
RGSC_v3.41187,248,119 - 87,248,301UniSTSRGSC3.4
Celera1184,076,907 - 84,077,089UniSTS
RH 3.4 Map11630.1UniSTS
Cytogenetic Map11q23UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111901627290463843Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115785881090463843Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115994302390463843Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116449467190463843Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116964970890463843Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:231
Count of miRNA genes:153
Interacting mature miRNAs:178
Transcripts:ENSRNOT00000031401
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 31 54 38 19 38 8 10 74 34 41 11 8
Low 12 3 3 3 1 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000031401   ⟹   ENSRNOP00000062102
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1189,557,273 - 89,591,175 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088212   ⟹   ENSRNOP00000068914
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1189,569,489 - 89,588,385 (+)Ensembl
RefSeq Acc Id: NM_183052   ⟹   NP_898875
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21185,304,528 - 85,338,430 (+)NCBI
Rnor_6.01189,557,273 - 89,591,175 (+)NCBI
Rnor_5.01192,611,596 - 92,645,498 (+)NCBI
RGSC_v3.41187,215,842 - 87,249,726 (+)RGD
Celera1184,044,758 - 84,078,508 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597891   ⟹   XP_017453380
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21185,304,765 - 85,336,374 (+)NCBI
Rnor_6.01189,557,530 - 89,589,119 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597892   ⟹   XP_017453381
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01189,557,707 - 89,589,119 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039088057   ⟹   XP_038943985
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21185,304,533 - 85,336,374 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_898875   ⟸   NM_183052
- UniProtKB: Q7M767 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_017453380   ⟸   XM_017597891
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017453381   ⟸   XM_017597892
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000062102   ⟸   ENSRNOT00000031401
RefSeq Acc Id: ENSRNOP00000068914   ⟸   ENSRNOT00000088212
RefSeq Acc Id: XP_038943985   ⟸   XM_039088057
- Peptide Label: isoform X2
Protein Domains
UBC core

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698353
Promoter ID:EPDNEW_R8878
Type:multiple initiation site
Name:Ube2v2_1
Description:ubiquitin conjugating enzyme E2 V2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01189,557,294 - 89,557,354EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727838 AgrOrtholog
Ensembl Genes ENSRNOG00000001829 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000062102 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000068914 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031401 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000088212 UniProtKB/TrEMBL
Gene3D-CATH 3.10.110.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7310168 IMAGE-MGC_LOAD
InterPro UBQ-conjugat_E2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBQ-conjugating_enzyme/RWD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:287927 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105268 IMAGE-MGC_LOAD
NCBI Gene 287927 ENTREZGENE
Pfam UQ_con UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB UBE2V2 RGD
PhenoGen Ube2v2 PhenoGen
PROSITE UBIQUITIN_CONJUGAT_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54495 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JU07_RAT UniProtKB/TrEMBL
  Q7M767 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q8CHN0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-22 Ube2v2  ubiquitin conjugating enzyme E2 V2  Ube2v2  ubiquitin-conjugating enzyme E2 variant 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Ube2v2  ubiquitin-conjugating enzyme E2 variant 2      Symbol and Name status set to approved 1299863 APPROVED