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Gene: Ddt (D-dopachrome tautomerase) Rattus norvegicus
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Symbol: Ddt
Name: D-dopachrome tautomerase
Description: Predicted to have cytokine receptor binding activity; phenylpyruvate tautomerase activity; and protease binding activity. Predicted to be involved in several processes, including negative regulation of macrophage chemotaxis; positive regulation of ERK1 and ERK2 cascade; and positive regulation of tumor necrosis factor production. Predicted to localize to the extracellular space. Orthologous to human DDT (D-dopachrome tautomerase) and DDTL (D-dopachrome tautomerase like); INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 3',5'-cyclic AMP; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: D-dopachrome decarboxylase; dopachrome isomerase
Orthologs:
Homo sapiens (human) : DDT (D-dopachrome tautomerase)  HGNC  Alliance
Mus musculus (house mouse) : Ddt (D-dopachrome tautomerase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddt (D-dopachrome tautomerase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100991346 (D-dopachrome decarboxylase)
Canis lupus familiaris (dog) : DDT (D-dopachrome tautomerase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101963449 (D-dopachrome decarboxylase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02013,827,153 - 13,829,624 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02016,016,838 - 16,019,309 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,591,785 - 13,594,256 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12013,592,013 - 13,594,480 (-)NCBI
Celera2014,375,891 - 14,378,362 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ddt
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 61923
Created: 2001-04-11
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.