LOC101963449 (D-dopachrome decarboxylase) - Rat Genome Database

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Gene: LOC101963449 (D-dopachrome decarboxylase) Ictidomys tridecemlineatus
Analyze
Symbol: LOC101963449
Name: D-dopachrome decarboxylase
RGD ID: 12574804
Description: ENCODES a protein that exhibits cytokine receptor binding (ortholog); D-dopachrome decarboxylase activity (ortholog); INVOLVED IN negative regulation of macrophage chemotaxis (ortholog); positive regulation of ERK1 and ERK2 cascade (ortholog); positive regulation of tumor necrosis factor production (ortholog); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); schizophrenia (ortholog); FOUND IN extracellular space (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: D-dopachrome tautomerase; Ddt
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,709,010 - 141,711,056 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366191,043,006 - 1,045,054 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
LOC101963449
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118141,709,010 - 141,711,056 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366191,043,006 - 1,045,054 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DDT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382223,971,370 - 23,980,504 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2223,970,542 - 23,980,525 (-)EnsemblGRCh38hg38GRCh38
GRCh372224,313,559 - 24,322,695 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362222,643,554 - 22,652,019 (-)NCBINCBI36Build 36hg18NCBI36
Build 342222,638,114 - 22,646,573NCBI
Celera228,114,132 - 8,122,585 (-)NCBICelera
Cytogenetic Map22q11.23NCBI
HuRef227,261,709 - 7,270,163 (-)NCBIHuRef
CHM1_12224,326,074 - 24,334,537 (-)NCBICHM1_1
T2T-CHM13v2.02224,378,787 - 24,387,911 (-)NCBIT2T-CHM13v2.0
Ddt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391075,607,067 - 75,609,208 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1075,607,064 - 75,609,248 (-)EnsemblGRCm39 Ensembl
GRCm381075,771,233 - 75,773,374 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1075,771,230 - 75,773,414 (-)EnsemblGRCm38mm10GRCm38
MGSCv371075,233,978 - 75,236,119 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361075,214,949 - 75,217,090 (-)NCBIMGSCv36mm8
Celera1076,816,014 - 76,818,155 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1038.58NCBI
Ddt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82012,883,025 - 12,886,121 (+)NCBIGRCr8
mRatBN7.22012,884,216 - 12,886,687 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2012,884,243 - 12,888,482 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2013,590,792 - 13,593,263 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02012,951,735 - 12,954,206 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02013,424,018 - 13,426,496 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02013,827,153 - 13,829,624 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2013,827,132 - 13,831,588 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02016,016,838 - 16,019,309 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,591,785 - 13,594,256 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12013,592,013 - 13,594,480 (-)NCBI
Celera2014,375,891 - 14,378,362 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ddt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495545510,479,409 - 10,481,080 (-)NCBIChiLan1.0ChiLan1.0
LOC100991346
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12222,814,869 - 22,815,793 (-)NCBIpanpan1.1PanPan1.1panPan2
DDT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12628,520,189 - 28,522,539 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2627,594,091 - 27,596,448 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02629,924,321 - 29,926,680 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12628,008,355 - 28,010,711 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02627,624,962 - 27,627,316 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02628,614,196 - 28,616,556 (-)NCBIUU_Cfam_GSD_1.0
DDT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1449,790,804 - 49,793,357 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11449,790,794 - 49,793,196 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21453,233,009 - 53,235,411 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103223037
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1197,077,812 - 7,081,065 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666100282,915 - 286,125 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ddt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474712,473,181 - 12,474,898 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005334463 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005334463   ⟹   XP_005334520
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_024405118141,709,010 - 141,711,056 (+)NCBI
SpeTri2.0NW_0049366191,043,006 - 1,045,054 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005334520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSSTOP00000019793.2
GenBank Protein KAG3278781 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_005334520   ⟸   XM_005334463
- UniProtKB: I3N5Z7 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000034559 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000024238.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.429.10 UniProtKB/TrEMBL
InterPro Macrophage_inhib_fac UniProtKB/TrEMBL
  Tautomerase/MIF_sf UniProtKB/TrEMBL
NCBI Gene Ddt ENTREZGENE
PANTHER D-DOPACHROME DECARBOXYLASE UniProtKB/TrEMBL
  PTHR11954 UniProtKB/TrEMBL
Pfam MIF UniProtKB/TrEMBL
Superfamily-SCOP SSF55331 UniProtKB/TrEMBL
UniProt I3N5Z7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-07-13 LOC101963449  D-dopachrome decarboxylase  Ddt  D-dopachrome tautomerase  Symbol and/or name change 5135510 APPROVED