Cd69 (Cd69 molecule) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Cd69 (Cd69 molecule) Rattus norvegicus
Analyze
Symbol: Cd69
Name: Cd69 molecule
RGD ID: 61318
Description: Enables calcium ion binding activity. Predicted to be involved in cellular response to xenobiotic stimulus; negative regulation of T cell migration; and negative regulation of T-helper 17 cell lineage commitment. Predicted to be located in external side of plasma membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane. Orthologous to human CD69 (CD69 molecule); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C-type lectin domain family 2 member A; CD69 antigen; early activation antigen CD69
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Ciaa4 Cia24
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84164,411,485 - 164,419,403 (-)NCBIGRCr8
mRatBN7.24162,725,446 - 162,733,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4162,725,446 - 162,733,542 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4168,960,276 - 168,968,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04164,743,221 - 164,751,139 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04163,377,272 - 163,385,190 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04163,041,147 - 163,049,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,041,141 - 163,049,084 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04211,685,114 - 211,693,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44166,527,683 - 166,535,601 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14166,773,564 - 166,775,469 (-)NCBI
Celera4151,413,397 - 151,421,315 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-anisomycin  (ISO)
(-)-demecolcine  (ISO)
1-(5-isoquinolinesulfonyl)-2-methylpiperazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (ISO)
3-chloropropane-1,2-diol  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-(2-methylpiperazine-1-sulfonyl)isoquinoline  (ISO)
5-aza-2'-deoxycytidine  (ISO)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
beta-D-glucan  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (ISO)
bucladesine  (ISO)
buta-1,3-diene  (ISO)
Calcimycin  (ISO)
cannabidiol  (ISO)
capsiate  (ISO)
carbon nanotube  (ISO)
chloroprene  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (ISO)
dacarbazine  (ISO)
decabromodiphenyl ether  (EXP)
delta-tocotrienol  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dieldrin  (ISO)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
diuron  (ISO)
enniatin  (ISO)
erlotinib hydrochloride  (ISO)
ethyl methanesulfonate  (ISO)
flucloxacillin  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
gamma-hexachlorocyclohexane  (ISO)
graphite  (EXP)
halothane  (ISO)
hydroquinone  (ISO)
indole-3-methanol  (ISO)
ionomycin  (ISO)
isotretinoin  (ISO)
L-ascorbic acid  (ISO)
lipopolysaccharide  (ISO)
malathion  (ISO)
MC1568  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
mifepristone  (ISO)
mocetinostat  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-(6-acetamidohexyl)acetamide  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
ozone  (ISO)
paracetamol  (ISO)
Pentoxifylline  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
prostratin  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
tamibarotene  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
Theaflavin 3,3'-digallate  (ISO)
titanium dioxide  (ISO)
Tolmetin glucuronide  (ISO)
topotecan  (EXP)
Tributyltin oxide  (ISO)
trichloroacetic acid  (ISO)
trichostatin A  (ISO)
Triptolide  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Genetic dissection of a rat model for rheumatoid arthritis: significant gender influences on autosomal modifier loci Furuya T, etal., Hum Mol Genet 2000 Sep 22;9(15):2241-50
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Lymphocyte activation receptors: new structural paradigms in group V of C-type animal lectins. Pavlicek J, etal., Biochem Soc Trans 2004 Dec;32(Pt 6):1124-6.
6. Molecular characterization of binding of calcium and carbohydrates by an early activation antigen of lymphocytes CD69. Pavlicek J, etal., Biochemistry 2003 Aug 12;42(31):9295-306.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Functional analysis of ligand-binding and signal transduction domains of CD69 and CD23 C-type lectin leukocyte receptors. Sancho D, etal., J Immunol 2000 Oct 1;165(7):3868-75.
Additional References at PubMed
PMID:7589135   PMID:7630421   PMID:11101293   PMID:12477932   PMID:12697665   PMID:15184345   PMID:15240667   PMID:16227984   PMID:16301745   PMID:16973387   PMID:17082577   PMID:17137799  
PMID:18776904   PMID:18792410   PMID:18836449   PMID:19008373   PMID:19015308   PMID:19109165   PMID:19349303   PMID:19723499   PMID:20544345   PMID:21357543   PMID:21460847  


Genomics

Comparative Map Data
Cd69
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84164,411,485 - 164,419,403 (-)NCBIGRCr8
mRatBN7.24162,725,446 - 162,733,364 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4162,725,446 - 162,733,542 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4168,960,276 - 168,968,194 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04164,743,221 - 164,751,139 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04163,377,272 - 163,385,190 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04163,041,147 - 163,049,065 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,041,141 - 163,049,084 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04211,685,114 - 211,693,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44166,527,683 - 166,535,601 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14166,773,564 - 166,775,469 (-)NCBI
Celera4151,413,397 - 151,421,315 (-)NCBICelera
Cytogenetic Map4q42NCBI
CD69
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38129,752,486 - 9,760,901 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl129,752,486 - 9,760,901 (-)EnsemblGRCh38hg38GRCh38
GRCh37129,905,082 - 9,913,497 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36129,796,349 - 9,804,764 (-)NCBINCBI36Build 36hg18NCBI36
Build 34129,796,350 - 9,804,764NCBI
Celera1215,066,458 - 15,074,875 (-)NCBICelera
Cytogenetic Map12p13.31NCBI
HuRef129,648,014 - 9,656,429 (-)NCBIHuRef
CHM1_1129,874,021 - 9,882,437 (-)NCBICHM1_1
T2T-CHM13v2.0129,638,644 - 9,647,057 (-)NCBIT2T-CHM13v2.0
Cd69
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396129,244,287 - 129,252,332 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6129,244,288 - 129,252,399 (-)EnsemblGRCm39 Ensembl
GRCm386129,267,324 - 129,275,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6129,267,325 - 129,275,436 (-)EnsemblGRCm38mm10GRCm38
MGSCv376129,217,343 - 129,225,387 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366129,233,018 - 129,241,062 (-)NCBIMGSCv36mm8
Celera6130,989,995 - 130,998,041 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.21NCBI
Cd69
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554135,579,072 - 5,587,491 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554135,579,037 - 5,586,238 (+)NCBIChiLan1.0ChiLan1.0
CD69
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21015,243,088 - 15,251,508 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,239,847 - 15,248,267 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0129,800,446 - 9,808,874 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11210,049,668 - 10,058,094 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1210,049,668 - 10,058,094 (-)Ensemblpanpan1.1panPan2
CD69
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12736,197,202 - 36,205,045 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2736,197,175 - 36,204,597 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2710,416,968 - 10,424,807 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02736,545,864 - 36,553,699 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2736,545,852 - 36,553,251 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12736,429,091 - 36,436,930 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02736,456,497 - 36,464,333 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0279,942,252 - 9,950,090 (-)NCBIUU_Cfam_GSD_1.0
CD69
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl562,077,988 - 62,085,900 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1562,078,134 - 62,084,961 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2564,909,979 - 64,916,924 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap5q25NCBI
CD69
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1119,659,154 - 9,666,342 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl119,659,029 - 9,665,914 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660891,735,439 - 1,742,246 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cd69
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248604,345,232 - 4,365,817 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248604,345,497 - 4,364,251 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cd69
13 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:363
Count of miRNA genes:199
Interacting mature miRNAs:237
Transcripts:ENSRNOT00000010422
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 25 36 88 87 56 25 56 6 171 72 16 26 42 31

Sequence


Ensembl Acc Id: ENSRNOT00000091644   ⟹   ENSRNOP00000070664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4162,725,446 - 162,733,300 (-)Ensembl
Rnor_6.0 Ensembl4163,041,141 - 163,049,084 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119283   ⟹   ENSRNOP00000078398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4162,725,446 - 162,733,542 (-)Ensembl
RefSeq Acc Id: NM_134327   ⟹   NP_599154
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84164,411,485 - 164,419,403 (-)NCBI
mRatBN7.24162,725,446 - 162,733,364 (-)NCBI
Rnor_6.04163,041,147 - 163,049,065 (-)NCBI
Rnor_5.04211,685,114 - 211,693,033 (-)NCBI
RGSC_v3.44166,527,683 - 166,535,601 (-)RGD
Celera4151,413,397 - 151,421,315 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_599154 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH88219 (Get FASTA)   NCBI Sequence Viewer  
  AAL87637 (Get FASTA)   NCBI Sequence Viewer  
  ADK94898 (Get FASTA)   NCBI Sequence Viewer  
  EDM01751 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070664.2
  ENSRNOP00000078398.1
RefSeq Acc Id: NP_599154   ⟸   NM_134327
- UniProtKB: D9Z4I9 (UniProtKB/TrEMBL),   A0A8I6G1Q9 (UniProtKB/TrEMBL),   Q5M851 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070664   ⟸   ENSRNOT00000091644
Ensembl Acc Id: ENSRNOP00000078398   ⟸   ENSRNOT00000119283
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M851-F1-model_v2 AlphaFold Q5M851 1-199 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693432
Promoter ID:EPDNEW_R3957
Type:single initiation site
Name:Cd69_1
Description:Cd69 molecule
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04163,049,085 - 163,049,145EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61318 AgrOrtholog
BioCyc Gene G2FUF-42795 BioCyc
Ensembl Genes ENSRNOG00000056783 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000091644.2 UniProtKB/TrEMBL
  ENSRNOT00000119283.1 UniProtKB/TrEMBL
Gene3D-CATH 3.10.100.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7384461 IMAGE-MGC_LOAD
InterPro C-type_lectin UniProtKB/TrEMBL
  C-type_lectin-like UniProtKB/TrEMBL
  C-type_lectin/matrix_domain UniProtKB/TrEMBL
  C-type_lectin_fold UniProtKB/TrEMBL
  NKR-like_CTLD UniProtKB/TrEMBL
KEGG Report rno:29187 UniProtKB/TrEMBL
MGC_CLONE MGC:108945 IMAGE-MGC_LOAD
NCBI Gene 29187 ENTREZGENE
PANTHER C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN 180 UniProtKB/TrEMBL
  EARLY ACTIVATION ANTIGEN CD69 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/TrEMBL
PhenoGen Cd69 PhenoGen
PROSITE C_TYPE_LECTIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056783 RatGTEx
SMART CLECT UniProtKB/TrEMBL
Superfamily-SCOP C-type_lectin_fold UniProtKB/TrEMBL
UniProt A0A0G2JYI2_RAT UniProtKB/TrEMBL
  A0A8I6G1Q9 ENTREZGENE, UniProtKB/TrEMBL
  D9Z4I9 ENTREZGENE, UniProtKB/TrEMBL
  Q5M851 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-29 Cd69  Cd69 molecule  Cd69  CD69 antigen  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Cd69  CD69 antigen      Symbol and Name status set to approved 70585 APPROVED
2001-10-22 Cd69  CD69 antigen      Name updated 68916 PENDING

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction binds calcium 634727
gene_product member of the C-type lectin family 634727