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Gene: Tac1 (tachykinin, precursor 1) Rattus norvegicus
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Symbol: Tac1
Name: tachykinin, precursor 1
Description: Exhibits substance P receptor binding activity. Involved in several processes, including learning or memory; positive regulation of secretion; and positive regulation of synaptic transmission. Localizes to the extracellular space and plasma membrane. Used to study central sleep apnea and pulmonary hypertension. Biomarker of colitis and respiratory syncytial virus infectious disease. Orthologous to human TAC1 (tachykinin precursor 1); INTERACTS WITH (+)-pilocarpine; (RS)-amphetamine; (S)-amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: PPT; Ppt5fl; PPTA3; protachykinin-1; RATPPTA3; TAC; Tachykinin (substance P neurokinin A neuropeptide K neuropeptide gamma); Tachykinin (substance P, neurokinin A, neuropeptide K, neuropeptide gamma); tachykinin 1
Orthologs:
Homo sapiens (human) : TAC1 (tachykinin precursor 1)  HGNC  Alliance
Mus musculus (house mouse) : Tac1 (tachykinin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tac1 (tachykinin precursor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TAC1 (tachykinin precursor 1)
Canis lupus familiaris (dog) : TAC1 (tachykinin precursor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tac1 (tachykinin precursor 1)
Sus scrofa (pig) : TAC1 (tachykinin precursor 1)
more info ...
Is Marker For: Strains:   BB/OK  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0433,638,853 - 33,646,819 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0433,499,891 - 33,507,857 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4432,649,666 - 32,657,632 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1432,768,205 - 32,776,170 (+)NCBI
Celera431,183,136 - 31,191,779 (+)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tac1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3807
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.