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Gene: Nfkb2 (nuclear factor kappa B subunit 2) Rattus norvegicus
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Symbol: Nfkb2
Name: nuclear factor kappa B subunit 2
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and chromatin binding activity. Involved in aging; response to cytokine; and response to lipopolysaccharide. Localizes to the cytosol and nucleus. Human ortholog(s) of this gene implicated in common variable immunodeficiency. Orthologous to human NFKB2 (nuclear factor kappa B subunit 2); PARTICIPATES IN adenosine signaling pathway; interleukin-12 signaling pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC309452; MGC93816; nuclear factor NF-kappa-B p100 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; RGD1307189; similar to nuclear factor kappa B subunit p100
Orthologs:
Homo sapiens (human) : NFKB2 (nuclear factor kappa B subunit 2)  HGNC  Alliance
Mus musculus (house mouse) : Nfkb2 (nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfkb2 (nuclear factor kappa B subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NFKB2 (nuclear factor kappa B subunit 2)
Canis lupus familiaris (dog) : NFKB2 (nuclear factor kappa B subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfkb2 (nuclear factor kappa B subunit 2)
Sus scrofa (pig) : NFKB2 (nuclear factor kappa B subunit 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01266,050,634 - 266,059,277 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1266,053,002 - 266,059,256 (+)Ensembl
Rnor_5.01273,481,574 - 273,490,218 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,521,559 - 251,527,815 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11251,784,632 - 251,790,888 (+)NCBI
Celera1240,949,824 - 240,956,078 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Nfkb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307189
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.