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Gene: Ikbkg (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) Rattus norvegicus
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Symbol: Ikbkg
Name: inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
Description: Exhibits peroxisome proliferator activated receptor binding activity. Predicted to be involved in several processes, including anoikis; regulation of intracellular signal transduction; and regulation of transcription, DNA-templated. Localizes to the IkappaB kinase complex. Used to study irritable bowel syndrome and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in Behcet's disease; Bloch-Sulzberger syndrome; hypohidrotic ectodermal dysplasia; learning disability; and primary immunodeficiency disease. Orthologous to human IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma); PARTICIPATES IN FasL mediated signaling pathway; interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2-amino-2-deoxy-D-glucopyranose; aldehydo-D-glucosamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; ikB kinase-associated protein 1; IKK-gamma; IKKAP1; IKKG; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; inhibitor of nuclear factor kappa B kinase subunit gamma; inhibitor of nuclear factor kappa-B kinase subunit gamma; Nemo; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X156,254,187 - 156,280,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,257,173 - 156,270,748 (-)Ensembl
Rnor_5.01151,994,689 - 152,019,874 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,386,558 - 160,420,190 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X160,483,372 - 160,496,394 (+)NCBI
Celera1135,659,513 - 135,672,876 (-)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Ikbkg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735223
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.