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Gene: IKBKG (inhibitor of nuclear factor kappa B kinase regulatory subunit gamma) Pan paniscus

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Symbol:

IKBKG

Name:

inhibitor of nuclear factor kappa B kinase regulatory subunit gamma

RGD ID:

11864449

Description:

ENCODES a protein that exhibits peroxisome proliferator activated receptor binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN anoikis (ortholog); B cell homeostasis (ortholog); negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN FasL mediated signaling pathway; interleukin-1 signaling pathway; nuclear factor kappa B signaling pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); adrenoleukodystrophy (ortholog); autistic disorder (ortholog); FOUND IN cytosol (ortholog); IkappaB kinase complex (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of nuclear factor kappa B kinase subunit gamma; NF-kappa-B essential modulator

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	154,521,470 - 154,539,144 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	154,524,964 - 154,546,311 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,988,720 - 144,010,078 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	153,869,352 - 153,876,677 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	153,854,493 - 153,876,092 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acute myocardial infarction (ISO)

adrenoleukodystrophy (ISO)

autistic disorder (ISO)

autosomal hemophilia A (ISO)

Barth syndrome (ISO)

Behcet's disease (ISO)

Bloch-Sulzberger syndrome (ISO)

cerebral creatine deficiency syndrome 1 (ISO)

colorectal cancer (ISO)

common variable immunodeficiency (ISO)

congenital nonspherocytic hemolytic anemia 1 (ISO)

Coronary Disease (ISO)

dyskeratosis congenita (ISO)

ectodermal dysplasia and immune deficiency (ISO)

ectodermal dysplasia and immunodeficiency 1 (ISO)

Emery-Dreifuss muscular dystrophy (ISO)

Experimental Arthritis (ISO)

Experimental Liver Cirrhosis (ISO)

Experimental Liver Neoplasms (ISO)

Experimental Pancreatitis (ISO)

factor VIII deficiency (ISO)

favism (ISO)

genetic disease (ISO)

glucosephosphate dehydrogenase deficiency (ISO)

hepatitis (ISO)

hepatocellular carcinoma (ISO)

hypomelanosis of Ito (ISO)

immunodeficiency 33 (ISO)

irritable bowel syndrome (ISO)

learning disability (ISO)

liver cancer (ISO)

Liver Reperfusion Injury (ISO)

Lung Neoplasms (ISO)

malaria (ISO)

metabolic dysfunction-associated steatotic liver disease (ISO)

paraplegia (ISO)

perinatal necrotizing enterocolitis (ISO)

periventricular nodular heterotopia (ISO)

severe congenital encephalopathy due to MECP2 mutation (ISO)

Splenomegaly (ISO)

steatotic liver disease (ISO)

syndromic X-linked intellectual disability Lubs type (ISO)

Systemic Autoinflammatory Disease, X-Linked (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anoikis (ISO)

B cell homeostasis (ISO)

canonical NF-kappaB signal transduction (IEA)

defense response to bacterium (IEA)

DNA damage response (IEA)

establishment of vesicle localization (IEA)

negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (ISO)

positive regulation of canonical NF-kappaB signal transduction (IEA,ISO)

positive regulation of gene expression (ISO)

positive regulation of macroautophagy (ISO)

positive regulation of NF-kappaB transcription factor activity (ISO)

positive regulation of T cell receptor signaling pathway (IEA)

positive regulation of transcription by RNA polymerase II (IEA)

protein-containing complex assembly (IEA)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISO)

IkappaB kinase complex (IEA,ISO)

mitotic spindle (IEA)

nucleus (IEA)

protein-containing complex (IEA)

spindle pole (IEA)

ubiquitin ligase complex (IEA)

Molecular Function

identical protein binding (IEA)

K63-linked polyubiquitin modification-dependent protein binding (IEA)

linear polyubiquitin binding (IEA)

peroxisome proliferator activated receptor binding (ISO)

polyubiquitin modification-dependent protein binding (IEA)

protein binding (ISO)

protein domain specific binding (IEA)

protein heterodimerization activity (IEA)

protein homodimerization activity (IEA)

protein-containing complex binding (ISO)

signaling adaptor activity (IEA)

transferrin receptor binding (IEA)

ubiquitin protein ligase binding (IEA)

zinc ion binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

FasL mediated signaling pathway (ISO)

interleukin-1 signaling pathway (ISO)

nuclear factor kappa B signaling pathway (ISO)

Trail mediated signaling pathway (ISO)

tumor necrosis factor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

IKBKG
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	X	154,521,470 - 154,539,144 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	X	154,524,964 - 154,546,311 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	X	143,988,720 - 144,010,078 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	X	153,869,352 - 153,876,677 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	X	153,854,493 - 153,876,092 (+)	Ensembl	panpan1.1		panPan2

IKBKG
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	X	154,541,238 - 154,565,046 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	154,541,199 - 154,565,046 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	X	153,769,453 - 153,793,261 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	X	153,423,653 - 153,446,455 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	X	153,339,765 - 153,356,964	NCBI
Celera	X	153,931,508 - 153,953,200 (+)	NCBI		Celera
Cytogenetic Map	X	q28	NCBI
HuRef	X	142,346,885 - 142,356,952 (+)	NCBI		HuRef
CHM1_1	X	153,682,228 - 153,705,030 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	X	152,777,621 - 152,801,428 (+)	NCBI		T2T-CHM13v2.0

Ikbkg
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	X	73,436,883 - 73,498,013 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	X	73,436,896 - 73,497,460 (+)	Ensembl		GRCm39 Ensembl
GRCm38	X	74,393,233 - 74,456,792 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	X	74,393,290 - 74,453,854 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	X	71,638,630 - 71,699,117 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	X	70,682,424 - 70,704,240 (+)	NCBI		MGSCv36	mm8
Celera	X	65,647,484 - 65,706,592 (+)	NCBI		Celera
Cytogenetic Map	X	A7.3	NCBI
cM Map	X	38.0	NCBI

Ikbkg
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	X	157,358,279 - 157,397,563 (+)	NCBI		GRCr8
mRatBN7.2	X	152,216,485 - 152,241,476 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	X	152,216,596 - 152,239,499 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	X	154,366,048 - 154,379,411 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	X	157,928,859 - 157,942,222 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	X	155,601,075 - 155,614,438 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	X	156,254,187 - 156,280,046 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	X	156,257,173 - 156,270,748 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	1	151,994,689 - 152,019,874 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	X	160,386,558 - 160,420,190 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	X	160,483,372 - 160,496,394 (+)	NCBI
Celera	1	135,659,513 - 135,672,876 (-)	NCBI		Celera
Cytogenetic Map	X	q37	NCBI

Ikbkg
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955580	1,053,823 - 1,069,802 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955580	1,053,823 - 1,069,802 (+)	NCBI	ChiLan1.0	ChiLan1.0

IKBKG
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	122,232,052 - 122,253,499 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	122,235,878 - 122,250,562 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
ROS_Cfam_1.0	X	125,373,537 - 125,395,176 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	X	125,373,743 - 125,395,172 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	X	121,142,500 - 121,164,137 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	123,657,571 - 123,679,200 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	123,419,351 - 123,440,993 (+)	NCBI		UU_Cfam_GSD_1.0

Ikbkg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	X	119,519,768 - 119,569,193 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936809	1,257,654 - 1,301,813 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936809	1,280,254 - 1,306,964 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

IKBKG
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	X	125,036,508 - 125,056,453 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	X	125,035,575 - 125,056,445 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	X	143,478,840 - 143,498,934 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

IKBKG
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	X	128,781,975 - 128,816,039 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	X	128,787,785 - 128,806,083 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666065	66,774,279 - 66,797,151 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ikbkg
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624946	996,814 - 1,013,379 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624946	997,571 - 1,015,748 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008952821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034950011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034950012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034950013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034950014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034950015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034950016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000024	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000020891 ⟹ ENSPPAP00000004543

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	X	153,854,493 - 153,876,092 (+)	Ensembl

RefSeq Acc Id:

XM_008952821 ⟹ XP_008951069

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	154,521,524 - 154,539,144 (+)	NCBI
NHGRI_mPanPan1	X	154,525,348 - 154,542,751 (+)	NCBI
Mhudiblu_PPA_v0	X	143,989,234 - 144,006,530 (+)	NCBI
PanPan1.1	X	153,869,352 - 153,876,677 (+)	NCBI

Sequence:

show sequence

CAAGGAGTGGCTGCGGGGCCCTCGGGAAAGCCCCTGGGTTGTGGGTGCTACACAGATGTCTCAA
AGGGACAGGGTAAGCCCTTTGTAGTAAATGCTGTAAGAAAGGGAGGTCAGGTGTTGGCCGGAAC
AGACAGTAAATGCTCTGGGCAGCCCTGAGCGTTTCCAGACGGGAACTCACTCAAAAGGGGGCTG
GGGCGTCCCGGGGGCGCGGCCTTAGGCTCCCAGAGGCCCCGTGAGGTGGTGGCCGGGTGTCTTC
GGGCAGGGGTTTGAGTGCAGTGTGCCTGCCGAGAGGTTCTGCAGTTCCCAGTGTTTAACGAAAT
TCAGTGTCCACTCTTGATTTGCACAAACTCTCCCATCCTGGCGGCCCCGGGTGCGGACTGGGGC
CTGTGTTTACTTTGCCCTATTCGTGTCTGGCCTCCTTTTGTCCCAAGTCTCAGAGAGACGGAGA
GAGATCCCCTGCTGGGGCTGTAGCTGCAAGGCCACCGGGTTCAGCCCTCAAGGCCTGCTTGCCG
GGGCAGTGACTAAGCCGTTGACAACCTCAAGGCAGCTTTGTGCTCCTTCGTCTCTTTGGGGATC
TCTTTTTGCCCCATCTGTGTGTCACCCTGTGGCAGAGGGTTAAGGTGGGCAGCTGGGGAGGGTT
GGGTGGCCCTTGGGCTCATGAGGCCCTAGGGCACCCAGGTTTGGGGGTGCCGAGGGCAGGAAAA
AAGGCCTCATGGCGCGCAGGCCTCAGCCGCTTGCGGGTTGCCCCAGGCTTGCGGATGGCAGGAG
TGGGCCGCTGGGGAGAAAGCAGTGCTGACAGGAAGTGGCTTTTTATCCTGCAGCAGATGGCTGA
GGACAAGGCCTCTGTGAAAGCCCAGGTGACGTCCTTGCTCGGGGAGCTGCAGGAGAGCCAGAGT
CGCTTGGAGGCTGCCACTAAGGAATGCCAGGCTCTGGAGGGTCGGGCCCGGGCGGCCAGCGAGC
AGGCGCGGCAGCTGGAGAGTGAGCGCGAGGCGCTGCAGCAGCAGCACAGCGTGCAGGTGGACCA
GCTGCGCATGCAGGGCCAGAGCGTGGAGGCCGCGCTCCGCATGGAGCGCCAGGCCGCCTCGGAG
GAGAAGAGGAAGCTGGCCCAGTTGCAGGTGGCCTATCACCAGCTCTTCCAAGAATACGACAACC
ACATCAAGAGCAGCGTGGTGGGCAGTGAGCGGAAGCGAGGAATGCAGCTGGAAGATCTCAAACA
GCAGCTCCAGCAGGCCGAGGAGGCCCTGGTGGCCAAACAGGAGGTGATCGATAAGCTGAAGGAG
GAGGCCGAGCAGCACAAGATTGTGATGGAGACCGTTCCGGTGCTGAAGGCCCAGGCGGATATCT
ACAAGGCGGACTTCCAGGCTGAGAGGCAGGCCCGGGAGAAGCTGGCTGAGAAGAAGGAGCTCCT
GCAGGAGCAGCTGGAGCAGCTGCAGAGGGAGTACAGCAAACTGAAGGCCAGCTGTCAGGAGTCG
GCCAGGATCGAGGACATGAGGAAGCGGCATGTCGAGGTCTCCCAGGCCCCCTTGCCCCCCGCCC
CTGCCTACCTCTCCTCTCCCCTGGCCCTGCCCAGCCAGAGGAGGAGCCCCCCCGAGGAGCCACC
TGACTTCTGCTGTCCCAAGTGCCAGTATCAGGCCCCTGATATGGACACCCTGCAGATACATGTC
ATGGAGTGCATTGAGTAGGGCCGGCCAGTGCAAGGCCACTGCCTGCCGAGGACGTGCCCGGGAC
CGTGCAGTCTGCGCTTTCCTCTCCCGCCTGCCTAGCCCAGGATGAAGGGCTGGGTGGCCACAAC
TGGGATGCCACCTGGAGCCCCACCCAGGAGCTGGGCGCGGCGCCTTACGCTTCAGCTGTTGATC
CGCTCGTCCCCTCTTTTGGGGTAGATGCGGCCCGGATCAGGCCTGACTCGCTGCTCTTTTTGTT
CCCTTCTGTCTGCTCGAACCACTTGCCTCGGGCTAATCCCTCCCTCTTCCTCCACCCGGCACTG
GGGAAGTCAAGAATGGGGCCTGGGGCTCTCAGGGAGAACTGCTTCCCCTGGCAGAGCTGGGTGG
CAGCTCTTCCTCCCACCGGACACCGACCCGCCCGCCGCTGTGCCCTGGGAGTGCTGCCCTCTTA
CCATGCACACGGGTGCTCTCCTTTTGGGCTGCATGCTATTCCATTTTGCAGCCAGACCGATGTG
TATTTAACCAGTCACTATTGATGGACATTTGGGTTGTTTCCCATCTTTTTGTTACCATAAATAA
TGGCATAGTAAAAATCCTTGTGCATTA

hide sequence

RefSeq Acc Id:

XM_034950011 ⟹ XP_034805902

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	154,521,524 - 154,539,144 (+)	NCBI
NHGRI_mPanPan1	X	154,525,211 - 154,542,751 (+)	NCBI
Mhudiblu_PPA_v0	X	143,988,720 - 144,006,530 (+)	NCBI

RefSeq Acc Id:

XM_034950012 ⟹ XP_034805903

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	154,521,470 - 154,539,144 (+)	NCBI
NHGRI_mPanPan1	X	154,525,211 - 154,542,751 (+)	NCBI
Mhudiblu_PPA_v0	X	143,988,720 - 144,006,530 (+)	NCBI

RefSeq Acc Id:

XM_034950014 ⟹ XP_034805905

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	154,521,524 - 154,539,144 (+)	NCBI
NHGRI_mPanPan1	X	154,525,198 - 154,542,751 (+)	NCBI
Mhudiblu_PPA_v0	X	143,988,720 - 144,006,530 (+)	NCBI

RefSeq Acc Id:

XM_034950015 ⟹ XP_034805906

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	154,521,524 - 154,539,144 (+)	NCBI
NHGRI_mPanPan1	X	154,525,195 - 154,542,751 (+)	NCBI
Mhudiblu_PPA_v0	X	143,988,720 - 144,006,530 (+)	NCBI

RefSeq Acc Id:

XM_034950016 ⟹ XP_034805907

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	X	154,521,524 - 154,539,144 (+)	NCBI
NHGRI_mPanPan1	X	154,525,196 - 154,542,751 (+)	NCBI
Mhudiblu_PPA_v0	X	143,988,720 - 144,006,530 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008951069	(Get FASTA)	NCBI Sequence Viewer
	XP_034805902	(Get FASTA)	NCBI Sequence Viewer
	XP_034805903	(Get FASTA)	NCBI Sequence Viewer
	XP_034805905	(Get FASTA)	NCBI Sequence Viewer
	XP_034805906	(Get FASTA)	NCBI Sequence Viewer
	XP_034805907	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000004543.1

RefSeq Acc Id:	XP_008951069 ⟸ XM_008952821
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZP21 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAGVGRWGESSADRKWLFILQQMAEDKASVKAQVTSLLGELQESQSRLEAATKECQALEGRARA ASEQARQLESEREALQQQHSVQVDQLRMQGQSVEAALRMERQAASEEKRKLAQLQVAYHQLFQE YDNHIKSSVVGSERKRGMQLEDLKQQLQQAEEALVAKQEVIDKLKEEAEQHKIVMETVPVLKAQ ADIYKADFQAERQAREKLAEKKELLQEQLEQLQREYSKLKASCQESARIEDMRKRHVEVSQAPL PPAPAYLSSPLALPSQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE hide sequence

RefSeq Acc Id:	XP_034805903 ⟸ XM_034950012
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZP21 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034805905 ⟸ XM_034950014
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_034805902 ⟸ XM_034950011
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R8ZP21 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034805906 ⟸ XM_034950015
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_034805907 ⟸ XM_034950016
- Peptide Label:	isoform X5

Ensembl Acc Id:

ENSPPAP00000004543 ⟸ ENSPPAT00000020891

Protein Domains

CCHC NOA-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000019041	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000020891.1	UniProtKB/TrEMBL
Gene3D-CATH	L1 transposable element, trimerization domain	UniProtKB/TrEMBL
	Nemo cc2-lz domain - 1d5 darpin complex	UniProtKB/TrEMBL
InterPro	CC2-LZ_dom	UniProtKB/TrEMBL
	NEMO_ZF	UniProtKB/TrEMBL
	Optineurin/NFkB_EssMod	UniProtKB/TrEMBL
NCBI Gene	IKBKG	ENTREZGENE
PANTHER	NF-KAPPA-B ESSENTIAL MODULATOR	UniProtKB/TrEMBL
	NF-KAPPA-B ESSENTIAL MODULATOR	UniProtKB/TrEMBL
Pfam	CC2-LZ	UniProtKB/TrEMBL
	zf_C2H2_10	UniProtKB/TrEMBL
PROSITE	ZF_CCHC_NOA	UniProtKB/TrEMBL
UniProt	A0A2R8ZP21	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-02-19	IKBKG	inhibitor of nuclear factor kappa B kinase regulatory subunit gamma		inhibitor of nuclear factor kappa B kinase subunit gamma	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - PID (archival)