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Gene: Prpf6 (pre-mRNA processing factor 6) Rattus norvegicus
Symbol: Prpf6
Name: pre-mRNA processing factor 6
Description: Predicted to have several functions, including RNA binding activity; androgen receptor binding activity; and transcription coactivator activity. Predicted to be involved in RNA localization; positive regulation of transcription by RNA polymerase II; and spliceosomal tri-snRNP complex assembly. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa 60. Orthologous to human PRPF6 (pre-mRNA processing factor 6); PARTICIPATES IN spliceosome pathway; INTERACTS WITH Aroclor 1254; bisphenol A; 17alpha-ethynylestradiol (ortholog).
Type: protein-coding
Also known as: LOC366276; MGC156816; pre-mRNA-processing factor 6; PRP6 homolog; PRP6 pre-mRNA processing factor 6 homolog; PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae); PRP6 pre-mRNA splicing factor 6 homolog; PRP6 pre-mRNA splicing factor 6 homolog (S. cerevisiae); RGD1307103; similar to RIKEN cDNA 1190003A07; U5 snRNP-associated 102 kDa protein; U5-102 kDa protein
Homo sapiens (human) : PRPF6 (pre-mRNA processing factor 6)  HGNC  Alliance
Mus musculus (house mouse) : Prpf6 (pre-mRNA splicing factor 6)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : PRPF6 (pre-mRNA processing factor 6)
Canis lupus familiaris (dog) : PRPF6 (pre-mRNA processing factor 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prpf6 (pre-mRNA processing factor 6)
Sus scrofa (pig) : PRPF6 (pre-mRNA processing factor 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.03177,098,137 - 177,162,937 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.03180,807,600 - 180,871,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,740,406 - 170,804,674 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13170,646,458 - 170,710,709 (+)NCBI
Celera3163,816,537 - 163,880,658 (-)NCBICelera
Cytogenetic Map3q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Prpf6
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307103
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.