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G |
Ache |
acetylcholinesterase |
increases activity multiple interactions |
EXP |
Galactosamine results in increased activity of ACHE protein Vitamin U inhibits the reaction [Galactosamine results in increased activity of ACHE protein] |
CTD |
PMID:35673974 |
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
EXP |
Galactosamine results in increased expression of ACTA2 mRNA; Galactosamine results in increased expression of ACTA2 protein Genistein inhibits the reaction [Galactosamine results in increased expression of ACTA2 mRNA]; Genistein inhibits the reaction [Galactosamine results in increased expression of ACTA2 protein]; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of ACTA2 protein] |
CTD |
PMID:27836788 PMID:27876602 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actb |
actin, beta |
increases expression |
EXP |
Galactosamine results in increased expression of ACTB mRNA |
CTD |
PMID:22563491 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Afp |
alpha-fetoprotein |
increases expression |
EXP |
Galactosamine results in increased expression of AFP protein |
CTD |
PMID:61145 PMID:16965562 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of AKT1 protein]]; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of AKT1 protein; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:37934488 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions decreases expression increases expression |
EXP |
[ALB protein co-treated with [Lipopolysaccharides co-treated with Galactosamine]] results in increased expression of IL10 protein; [ALB protein co-treated with [Lipopolysaccharides co-treated with Galactosamine]] results in increased expression of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased expression of ALB protein; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased expression of ALB protein] Galactosamine results in decreased expression of ALB protein Galactosamine results in increased expression of ALB mRNA |
CTD |
PMID:17963606 PMID:18779383 PMID:22310181 PMID:35838105 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Ambp |
alpha-1-microglobulin/bikunin precursor |
increases expression |
EXP |
Galactosamine results in increased expression of AMBP mRNA |
CTD |
PMID:18779383 |
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NCBI chr 5:76,568,094...76,578,416
Ensembl chr 5:76,568,094...76,578,331
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G |
Apoe |
apolipoprotein E |
decreases expression |
EXP |
Galactosamine results in decreased expression of APOE protein |
CTD |
PMID:6631239 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
EXP |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 protein]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of ATF4 protein |
CTD |
PMID:28844859 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atm |
ATM serine/threonine kinase |
increases expression multiple interactions |
EXP |
Galactosamine results in increased expression of ATM protein glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of ATM protein] |
CTD |
PMID:24565947 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of BAX protein]]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of BAX protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of BAX protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of BAX protein modified form; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of BAX protein modified form]; GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of BAX protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of BAX protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of BAX protein modified form] Galactosamine results in increased expression of BAX mRNA; Galactosamine results in increased expression of BAX protein [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of BAX mRNA; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of BAX mRNA] |
CTD |
PMID:20558151 PMID:20850421 PMID:21401295 PMID:22118634 PMID:24565947 PMID:37934488 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of BCL2 protein]]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of BCL2 protein; [Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of BCL2 protein; [Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of BCL2 protein modified form; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of BCL2 protein modified form]; GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of BCL2 protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of BCL2 protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of BCL2 protein modified form] glycine propionyl carnitine inhibits the reaction [Galactosamine results in decreased expression of BCL2 mRNA]; mangiferin inhibits the reaction [Galactosamine results in decreased expression of BCL2 protein] Galactosamine results in decreased expression of BCL2 mRNA; Galactosamine results in decreased expression of BCL2 protein |
CTD |
PMID:20558151 PMID:20850421 PMID:22118634 PMID:24565947 PMID:37934488 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
EXP |
[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of BID mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of BID protein |
CTD |
PMID:12907702 PMID:21401295 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Casp1 |
caspase 1 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP1 protein; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP1 protein] |
CTD |
PMID:32453893 |
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression increases activity |
ISO EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of CASP3 protein]]; 3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of CASP3 protein]; [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein; [Galactosamine co-treated with Endotoxins] results in increased activity of CASP3 protein; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of CASP3 protein; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP3 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP3 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP3 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP3 protein modified form; [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]; [Nitric Oxide Donors results in increased abundance of Nitric Oxide] inhibits the reaction [[TNF protein co-treated with Galactosamine] results in increased activity of CASP3 protein]; [TNF protein co-treated with Galactosamine] results in increased activity of CASP3 protein; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP3 protein modified form]; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP3 protein]; Biliverdine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]; cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [Galactosamine results in increased activity of CASP3 protein]]; Dithiothreitol inhibits the reaction [Nitric Oxide Donors inhibits the reaction [[TNF protein co-treated with Galactosamine] results in increased activity of CASP3 protein]]; GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of CASP3 protein]; gentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP3 protein modified form]; Melatonin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP3 protein]; Methylene Chloride inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased cleavage of CASP3 protein]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP3 protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of CASP3 protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP3 protein modified form]; TNF protein promotes the reaction [Galactosamine results in increased activity of CASP3 protein]; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP3 protein] [Galactosamine co-treated with TNF protein] results in increased activity of CASP3 protein; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein; Ketoconazole inhibits the reaction [Galactosamine results in increased activity of CASP3 protein]; Rifampin promotes the reaction [Galactosamine results in increased activity of CASP3 protein] Galactosamine results in increased expression of CASP3 mRNA; Galactosamine results in increased expression of CASP3 protein 2-Acetylaminofluorene inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of CASP3 protein]; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP3 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased cleavage of CASP3 protein; Alprostadil inhibits the reaction [Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein]; Galactosamine results in increased cleavage of and results in increased activity of CASP3 protein; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of CASP3 mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of CASP3 protein] |
CTD |
PMID:9388267 PMID:12907702 PMID:14512878 PMID:15486963 PMID:15565661 PMID:15610455 PMID:17602819 PMID:17936189 PMID:20558151 PMID:20850421 PMID:21146893 PMID:21401295 PMID:22023962 PMID:22118634 PMID:22310181 PMID:24565947 PMID:24830863 PMID:26176423 PMID:28887131 PMID:31332890 PMID:32453893 PMID:37934488 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP7 protein] |
CTD |
PMID:21146893 |
|
NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of CASP8 protein]; [Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP8 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP8 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP8 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP8 protein modified form; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP8 protein modified form]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP8 protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP8 protein modified form]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP8 protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CASP8 protein modified form]; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of CASP8 protein] |
CTD |
PMID:20558151 PMID:20850421 PMID:21146893 PMID:24830863 PMID:31332890 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression |
ISO EXP |
3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of CASP9 protein]; [Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP9 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP9 protein modified form; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP9 protein; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP9 protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CASP9 protein modified form]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of CASP9 protein] mangiferin inhibits the reaction [Galactosamine results in increased expression of CASP9 protein] |
CTD |
PMID:20558151 PMID:22118634 PMID:24830863 PMID:31332890 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions increases activity decreases activity |
ISO EXP |
6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased activity of CAT protein]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]; [Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of CAT protein; [Lipopolysaccharides co-treated with Galactosamine] results in decreased activity of CAT protein; [Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]; Caffeine inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of CAT protein]; Hemin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]; Oligopeptides inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of CAT protein]] Galactosamine results in increased activity of CAT protein Galactosamine results in decreased activity of CAT protein [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased activity of CAT protein; glycine propionyl carnitine inhibits the reaction [Galactosamine results in decreased activity of CAT protein]; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased activity of CAT protein]; Vitamin U inhibits the reaction [Galactosamine results in decreased activity of CAT protein] |
CTD |
PMID:19153979 PMID:22154906 PMID:27836788 PMID:30236599 PMID:31022331 PMID:32453893 PMID:35673974 PMID:35691465 PMID:35838105 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CCL2 mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased secretion of CCL2 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein]; Hemin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CCL2 mRNA]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein]; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CCL2 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased secretion of CCL2 protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of CCL2 protein]] |
CTD |
PMID:21146893 PMID:28887131 PMID:35691465 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CCL5 mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased secretion of CCL5 protein; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of CCL5 mRNA]; Ursodeoxycholic Acid analog inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased secretion of CCL5 protein] |
CTD |
PMID:21146893 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CEBPA protein; Indomethacin promotes the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CEBPA protein]; nimesulide promotes the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CEBPA protein] |
CTD |
PMID:22107987 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CFLAR protein; baicalein inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CFLAR protein]; Silymarin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of CFLAR protein] |
CTD |
PMID:20850421 |
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NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
increases phosphorylation multiple interactions |
EXP |
Galactosamine results in increased phosphorylation of CHUK protein mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of CHUK protein] |
CTD |
PMID:22310181 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Col1a1 |
collagen type I alpha 1 chain |
increases expression multiple interactions |
EXP |
Galactosamine results in increased expression of COL1A1 mRNA Genistein inhibits the reaction [Galactosamine results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27876602 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions increases expression |
EXP |
Genistein inhibits the reaction [Galactosamine results in increased expression of COL3A1 mRNA] |
CTD |
PMID:27876602 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
multiple interactions decreases expression |
ISO |
alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CPT1A mRNA] |
CTD |
PMID:17936189 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[Galactosamine co-treated with Endotoxins] results in increased expression of CXCL2 mRNA; [Galactosamine co-treated with Endotoxins] results in increased expression of CXCL2 protein |
CTD |
PMID:15576625 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[Galactosamine co-treated with Endotoxins] results in increased expression of CXCL1 mRNA; [Galactosamine co-treated with Endotoxins] results in increased expression of CXCL1 protein |
CTD |
PMID:15576625 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions |
ISO |
[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CYBA protein; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of CYBA protein] |
CTD |
PMID:28887131 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in increased localization of CYCS protein; [Lipopolysaccharides co-treated with Galactosamine] affects the localization of CYCS protein; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of CYCS protein]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased localization of CYCS protein] |
CTD |
PMID:20558151 PMID:20850421 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression |
EXP |
Galactosamine results in decreased expression of CYP1A2 protein |
CTD |
PMID:16208626 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression multiple interactions |
EXP |
Galactosamine results in decreased expression of CYP2E1 protein [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of CYP2E1 protein; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of CYP2E1 protein] |
CTD |
PMID:16208626 PMID:35838105 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
decreases expression multiple interactions |
ISO |
Galactosamine results in decreased expression of CYP3A4 mRNA alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of CYP3A4 mRNA]; Galactosamine inhibits the reaction [alpha-Tocopherol results in increased expression of CYP3A4 mRNA]; Galactosamine inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:17936189 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
EXP |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of DDIT3 mRNA]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of DDIT3 mRNA |
CTD |
PMID:28844859 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
EXP |
[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of EGFR mRNA; [Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of EGFR protein; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of EGFR mRNA]; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of EGFR protein]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of EGFR mRNA]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of EGFR protein] |
CTD |
PMID:36414212 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
EXP |
4-phenylbutyric acid affects the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased phosphorylation of EIF2S1 protein]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of EIF2S1 mRNA]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of and results in decreased phosphorylation of EIF2S1 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of EIF2S1 mRNA |
CTD |
PMID:28844859 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions |
EXP |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased activity of G6PD protein; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased activity of G6PD protein] |
CTD |
PMID:35838105 |
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NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLC mRNA]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLC mRNA; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLC mRNA] |
CTD |
PMID:35691465 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GCLM mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GCLM mRNA] |
CTD |
PMID:28887131 PMID:35691465 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gdf11 |
growth differentiation factor 11 |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of BAX protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GPT protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of AKT1 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of MTOR protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of PIK3R1 protein]]; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GDF11 protein; GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the cleavage of CASP3 protein]; GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of BAX protein]; GDF11 protein affects the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] affects the expression of BCL2 protein]; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GPT protein]; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of AKT1 protein]; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of MTOR protein]; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of PIK3R1 protein] |
CTD |
PMID:37934488 |
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NCBI chr 7:1,311,732...1,325,211
Ensembl chr 7:1,311,732...1,320,725
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases expression |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of GPT protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of GPT protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased activity of GPT protein; [Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of GPT protein; Genistein inhibits the reaction [Galactosamine results in increased expression of GPT protein]; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of GPT protein]; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of GPT protein]; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of GPT protein]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of GPT protein] (2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline) inhibits the reaction [beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]]; (2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline) inhibits the reaction [ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GPT protein]]; 3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GPT protein]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of GPT protein]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein; [Galactosamine co-treated with Lipopolysaccharides] promotes the reaction [idelalisib results in increased expression of ALT protein]; [Galactosamine co-treated with Lipopolysaccharides] promotes the reaction [Miransertib results in increased expression of ALT protein]; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of GPT protein; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GPT protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of GPT protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased activity of GPT protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GPT protein; Acetylcysteine inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]; Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of GPT protein]; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of GPT protein]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]; Plant Extracts inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GPT protein]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of GPT protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of GPT protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of GPT protein]; stattic inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein] |
CTD |
PMID:19153979 PMID:24565947 PMID:24830863 PMID:25620059 PMID:27876602 PMID:28844859 PMID:28887131 PMID:30236599 PMID:30822415 PMID:31332890 PMID:31445927 PMID:32453893 PMID:35838105 PMID:36414212 PMID:37934488 More...
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity |
EXP |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased activity of GSR protein; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in decreased activity of GSR protein]; Vitamin U inhibits the reaction [Galactosamine results in decreased activity of GSR protein] |
CTD |
PMID:35673974 PMID:35838105 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
H3f4 |
H3.4 histone, cluster member |
increases expression |
EXP |
Galactosamine results in increased expression of H3F4 mRNA |
CTD |
PMID:11779202 |
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NCBI chr10:43,740,702...43,741,262
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G |
Habp2 |
hyaluronan binding protein 2 |
increases activity |
ISO |
Galactosamine results in increased activity of HABP2 protein |
CTD |
PMID:11510480 |
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NCBI chr 1:255,315,870...255,350,161
Ensembl chr 1:255,315,915...255,350,160
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions |
ISO |
[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HBEGF mRNA; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HBEGF mRNA]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of HBEGF mRNA] |
CTD |
PMID:28887131 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hgf |
hepatocyte growth factor |
multiple interactions |
EXP |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of HGF mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of HGF protein]; [Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of HGF mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of HGF protein |
CTD |
PMID:28844859 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions decreases expression |
ISO EXP |
8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA]; 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 protein]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 protein; Galactosamine inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA]; Hemin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 protein]; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA]]; zinc protoporphyrin inhibits the reaction [8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 protein]] Galactosamine results in decreased expression of HMOX1 protein [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of HMOX1 mRNA] which results in increased chemical synthesis of Bilirubin; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of HMOX1 mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of HMOX1 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA; mangiferin inhibits the reaction [Galactosamine results in decreased expression of HMOX1 protein]; purpurin anthraquinone inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HMOX1 mRNA] |
CTD |
PMID:14512878 PMID:19796704 PMID:21401295 PMID:22310181 PMID:35691465 PMID:35838105 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hp |
haptoglobin |
multiple interactions |
EXP |
[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of HP protein; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of HP protein]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of HP protein] |
CTD |
PMID:36414212 |
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NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HSPA5 protein]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HSPA5 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of HSPA5 protein |
CTD |
PMID:28844859 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Galactosamine analog inhibits the reaction [TNF results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Ifng |
interferon gamma |
multiple interactions increases expression |
ISO EXP |
[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IFNG mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IFNG protein; [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IFNG protein]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IFNG mRNA]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IFNG protein] mangiferin inhibits the reaction [Galactosamine results in increased expression of IFNG mRNA] |
CTD |
PMID:15486963 PMID:22310181 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
increases expression |
EXP |
Galactosamine results in increased expression of IGFBP1 mRNA |
CTD |
PMID:11779202 |
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NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions increases phosphorylation |
EXP |
mangiferin inhibits the reaction [Galactosamine results in increased phosphorylation of IKBKB protein] |
CTD |
PMID:22310181 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
multiple interactions decreases expression |
ISO EXP |
[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL10 protein; [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL10 protein]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL10 protein] Galactosamine results in decreased expression of IL10 mRNA [ALB protein co-treated with [Lipopolysaccharides co-treated with Galactosamine]] results in increased expression of IL10 protein; mangiferin inhibits the reaction [Galactosamine results in decreased expression of IL10 mRNA] |
CTD |
PMID:15486963 PMID:17963606 PMID:22310181 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il12b |
interleukin 12B |
multiple interactions increases expression |
ISO EXP |
[LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA mangiferin inhibits the reaction [Galactosamine results in increased expression of IL12B mRNA] |
CTD |
PMID:19913045 PMID:22310181 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il18 |
interleukin 18 |
increases expression multiple interactions |
ISO EXP |
Galactosamine results in increased expression of IL18 mRNA; Galactosamine results in increased expression of IL18 protein mangiferin inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA] [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 mRNA; [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 protein; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 mRNA; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 protein; Plant Preparations inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA]; Plant Preparations inhibits the reaction [Galactosamine results in increased expression of IL18 protein] |
CTD |
PMID:19913045 PMID:20102673 PMID:22310181 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
EXP ISO |
Genistein inhibits the reaction [Galactosamine results in increased expression of IL1B mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of IL1B mRNA] 2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B mRNA]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA; [Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B mRNA]; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL1B protein]; Hemin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]; nilotinib inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of IL1B protein]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL1B mRNA]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B mRNA]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL1B protein]] |
CTD |
PMID:15135310 PMID:22310181 PMID:25620059 PMID:28125915 PMID:28887131 PMID:30550845 PMID:32453893 PMID:35691465 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
ISO EXP |
3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL6 protein]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 mRNA]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL6 mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL6 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein; [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 mRNA]; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; Hemin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL6 mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of IL6 protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 mRNA]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of IL6 protein]] Galactosamine results in increased expression of IL6 mRNA [Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of IL6 protein; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of IL6 mRNA]; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of IL6 protein]; mangiferin inhibits the reaction [Galactosamine results in increased expression of IL6 mRNA]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of IL6 protein] |
CTD |
PMID:15135310 PMID:15486963 PMID:22310181 PMID:24830863 PMID:27836788 PMID:28887131 PMID:31332890 PMID:32453893 PMID:35691465 PMID:36414212 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions |
ISO |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of IRAK1 protein; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]] |
CTD |
PMID:28213090 |
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NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein]; [Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein]; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased degradation of KEAP1 protein] |
CTD |
PMID:35691465 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Lcat |
lecithin cholesterol acyltransferase |
decreases activity |
EXP |
Galactosamine results in decreased activity of LCAT protein |
CTD |
PMID:6631239 |
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NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Lep |
leptin |
multiple interactions increases response to substance |
ISO |
[LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA; [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 mRNA; [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 protein; [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of SPP1 protein; Galactosamine promotes the reaction [LEP gene mutant form results in increased expression of SPP1 mRNA]; Galactosamine promotes the reaction [LEP gene mutant form results in increased expression of SPP1 protein]; SPP1 promotes the reaction [LEP gene mutant form results in increased susceptibility to Galactosamine] |
CTD |
PMID:19913045 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lepr |
leptin receptor |
multiple interactions increases response to substance |
ISO |
[LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL12B mRNA; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 mRNA; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 protein; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of SPP1 protein; Galactosamine promotes the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA]; Galactosamine promotes the reaction [LEPR gene mutant form results in increased expression of SPP1 protein]; SPP1 promotes the reaction [LEPR gene mutant form results in increased susceptibility to Galactosamine] |
CTD |
PMID:19913045 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in decreased phosphorylation of MAPK1 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK1 protein modified form; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK1 protein modified form]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK1 protein modified form] Genistein inhibits the reaction [Galactosamine results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:20558151 PMID:20850421 PMID:25620059 PMID:28887131 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in decreased phosphorylation of MAPK3 protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK3 protein modified form; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MAPK3 protein modified form]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of MAPK3 protein modified form] Galactosamine results in increased phosphorylation of MAPK3 protein Genistein inhibits the reaction [Galactosamine results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:20558151 PMID:20850421 PMID:25620059 PMID:28887131 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Maz |
MYC associated zinc finger protein |
multiple interactions |
EXP |
[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of MAZ mRNA; [Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of MAZ protein; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of MAZ mRNA]; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of MAZ protein]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of MAZ mRNA]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of MAZ protein] |
CTD |
PMID:36414212 |
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NCBI chr 1:181,629,742...181,635,193
Ensembl chr 1:181,629,729...181,650,408
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G |
Met |
MET proto-oncogene, receptor tyrosine kinase |
multiple interactions |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of MET mRNA]; [Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of MET mRNA [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of MET mRNA |
CTD |
PMID:28844859 PMID:28887131 |
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NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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G |
Mgst1 |
microsomal glutathione S-transferase 1 |
multiple interactions |
EXP |
[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of MGST1 protein; Dithiothreitol inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased activity of MGST1 protein] |
CTD |
PMID:18634816 |
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NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
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G |
Mir34c |
microRNA 34c |
multiple interactions |
EXP |
[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MIR34C mRNA; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MIR34C mRNA]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in increased expression of MIR34C mRNA] |
CTD |
PMID:36414212 |
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NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
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G |
Mpo |
myeloperoxidase |
multiple interactions increases activity |
ISO EXP |
(2-(4-(4-isopropoxybenzyl)-phenylamino) imidazoline) inhibits the reaction [ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MPO protein]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MPO protein; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased activity of MPO protein; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MPO protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased activity of MPO protein]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MPO protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased activity of MPO protein] Galactosamine results in increased activity of MPO protein [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein]; Vitamin U inhibits the reaction [Galactosamine results in increased activity of MPO protein] |
CTD |
PMID:28887131 PMID:30550845 PMID:31022331 PMID:32453893 PMID:35673974 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mtor |
mechanistic target of rapamycin kinase |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of MTOR protein]]; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of MTOR protein; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of MTOR protein] |
CTD |
PMID:37934488 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Ndufb6 |
NADH:ubiquinone oxidoreductase subunit B6 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Galactosamine results in decreased expression of NDUFB6 mRNA]; coenzyme Q10 inhibits the reaction [Galactosamine results in decreased expression of NDUFB6 mRNA]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Galactosamine results in decreased expression of NDUFB6 mRNA] |
CTD |
PMID:19523936 |
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NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
affects localization increases activity multiple interactions decreases expression |
EXP ISO |
Galactosamine affects the localization of NFE2L2 protein Galactosamine results in increased activity of NFE2L2 protein [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFE2L2 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NFE2L2 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NFE2L2 protein; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFE2L2 mRNA]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NFE2L2 mRNA]; Plant Extracts promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NFE2L2 mRNA]; Plant Extracts promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NFE2L2 protein]; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NFE2L2 mRNA]; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NFE2L2 protein] mangiferin affects the reaction [Galactosamine affects the localization of NFE2L2 protein]; mangiferin inhibits the reaction [Galactosamine results in decreased expression of NFE2L2 protein] |
CTD |
PMID:22310181 PMID:28887131 PMID:30114225 PMID:30203046 PMID:30236599 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [NFKB1 protein binds to NFKB1 protein]]; alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]; Galactosamine results in increased activity of [NFKB1 protein binds to NFKB1 protein]; Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein] |
CTD |
PMID:17936189 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases expression |
EXP ISO |
Alprostadil inhibits the reaction [Galactosamine results in decreased expression of NFKBIA protein]; Enzyme Inhibitors inhibits the reaction [Alprostadil inhibits the reaction [Galactosamine results in decreased expression of NFKBIA protein]]; mangiferin inhibits the reaction [Galactosamine results in decreased expression of NFKBIA protein] [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased phosphorylation of NFKBIA protein; [Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of NFKBIA protein; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of NFKBIA protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of NFKBIA protein modified form]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased phosphorylation of NFKBIA protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in decreased expression of NFKBIA protein] |
CTD |
PMID:15565661 PMID:20850421 PMID:22310181 PMID:28213090 PMID:30550845 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein] |
CTD |
PMID:32453893 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression |
ISO EXP |
[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein; Indomethacin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]; Indomethacin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein] Galactosamine results in increased expression of NOS2 mRNA alpha-Tocopherol inhibits the reaction [Galactosamine results in increased expression of NOS2 mRNA] Galactosamine results in increased expression of NOS2 mRNA; Galactosamine results in increased expression of NOS2 promoter; Galactosamine results in increased expression of NOS2 protein [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA] which results in increased chemical synthesis of Nitrites; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of NOS2 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NOS2 mRNA; Alprostadil inhibits the reaction [Galactosamine results in increased expression of NOS2 mRNA]; Alprostadil inhibits the reaction [Galactosamine results in increased expression of NOS2 promoter]; Alprostadil inhibits the reaction [Galactosamine results in increased expression of NOS2 protein]; Enzyme Inhibitors inhibits the reaction [Alprostadil inhibits the reaction [Galactosamine results in increased expression of NOS2 protein]]; Galactosamine promotes the reaction [Alprostadil results in increased expression of NOS2 protein]; Genistein inhibits the reaction [Galactosamine results in increased expression of NOS2 protein]; mangiferin inhibits the reaction [Galactosamine results in increased expression of NOS2 protein]; resveratrol inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NOS2 mRNA] |
CTD |
PMID:15189274 PMID:15565661 PMID:17936189 PMID:19796704 PMID:21401295 PMID:22107987 PMID:22118634 PMID:22310181 PMID:25620059 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
decreases expression multiple interactions |
EXP ISO |
Galactosamine results in decreased expression of NQO1 protein 8-oxoberberine promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NQO1 protein]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of NQO1 mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NQO1 protein; Silymarin promotes the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NQO1 protein] mangiferin inhibits the reaction [Galactosamine results in decreased expression of NQO1 protein] |
CTD |
PMID:22310181 PMID:28887131 PMID:35691465 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Ocln |
occludin |
multiple interactions |
EXP |
[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of OCLN mRNA; [Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of OCLN mRNA]; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of OCLN mRNA]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of OCLN protein] |
CTD |
PMID:36414212 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein; gentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein] |
CTD |
PMID:20558151 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one affects the reaction [GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of PIK3R1 protein]]; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of PIK3R1 protein; GDF11 protein affects the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased phosphorylation of PIK3R1 protein] |
CTD |
PMID:37934488 |
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NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases expression multiple interactions increases activity decreases expression |
ISO |
Galactosamine results in increased expression of PPARA mRNA [Plant Extracts co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARA mRNA; [Plant Extracts co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARA protein; [Silymarin co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARA mRNA; [Silymarin co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARA protein Galactosamine results in increased activity of PPARA protein alpha-Tocopherol inhibits the reaction [Galactosamine results in decreased expression of PPARA mRNA] |
CTD |
PMID:17936189 PMID:25689681 PMID:30203046 PMID:30236599 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein; [Plant Extracts co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARG mRNA; [Plant Extracts co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARG protein; [Silymarin co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARG mRNA; [Silymarin co-treated with Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PPARG protein; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in decreased expression of PPARG protein] |
CTD |
PMID:30236599 PMID:30550845 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppia |
peptidylprolyl isomerase A |
decreases expression |
EXP |
Galactosamine results in decreased expression of CYCA mRNA |
CTD |
PMID:22563491 |
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NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of PTGS1 mRNA; Indomethacin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of PTGS1 mRNA]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of PTGS1 mRNA] |
CTD |
PMID:22107987 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO EXP |
[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of PTGS2 mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PTGS2 protein; Indomethacin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of PTGS2 mRNA]; Indomethacin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of PTGS2 mRNA]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of PTGS2 protein] Genistein inhibits the reaction [Galactosamine results in increased expression of PTGS2 protein] |
CTD |
PMID:22107987 PMID:25620059 PMID:32453893 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptn |
pleiotrophin |
increases expression |
EXP |
Galactosamine results in increased expression of PTN mRNA; Galactosamine results in increased expression of PTN protein |
CTD |
PMID:12057922 |
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NCBI chr 4:65,293,731...65,375,572
Ensembl chr 4:65,293,734...65,375,456
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
affects response to substance |
EXP |
PTTG1 mRNA affects the susceptibility to Galactosamine |
CTD |
PMID:19800905 |
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NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases expression |
ISO EXP |
[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form; [Lipopolysaccharides co-treated with Galactosamine] affects the localization of RELA protein; baicalein inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of RELA protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA mRNA]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of RELA protein modified form]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] affects the localization of RELA protein] alpha-Tocopherol inhibits the reaction [Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein]]; Galactosamine results in increased activity of [RELA protein binds to NFKB1 protein] mangiferin inhibits the reaction [Galactosamine results in increased expression of RELA protein] |
CTD |
PMID:17936189 PMID:20850421 PMID:22310181 PMID:30550845 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Sdc3 |
syndecan 3 |
increases expression |
EXP |
Galactosamine results in increased expression of SDC3 mRNA |
CTD |
PMID:12057922 |
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NCBI chr 5:142,965,659...142,998,390
Ensembl chr 5:142,965,591...142,996,480
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G |
Serpine1 |
serpin family E member 1 |
increases expression |
EXP |
Galactosamine results in increased expression of SERPINE1 mRNA |
CTD |
PMID:11779202 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sesn2 |
sestrin 2 |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of SESN2 mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of SESN2 protein |
CTD |
PMID:25637945 |
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NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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G |
Smad2 |
SMAD family member 2 |
multiple interactions increases phosphorylation |
EXP |
Genistein inhibits the reaction [Galactosamine results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:27876602 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases phosphorylation |
EXP |
Genistein inhibits the reaction [Galactosamine results in increased phosphorylation of SMAD3 protein] |
CTD |
PMID:27876602 |
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NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Smad7 |
SMAD family member 7 |
multiple interactions decreases expression |
EXP |
Genistein inhibits the reaction [Galactosamine results in decreased expression of SMAD7 protein] |
CTD |
PMID:27876602 |
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NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
[Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of SOD1 mRNA |
CTD |
PMID:21401295 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sord |
sorbitol dehydrogenase |
multiple interactions |
ISO |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of SORD protein; Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased activity of SORD protein] |
CTD |
PMID:30822415 |
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NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions |
ISO |
[LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of SPP1 protein; [LEPR gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of SPP1 protein; Galactosamine promotes the reaction [LEP gene mutant form results in increased expression of SPP1 mRNA]; Galactosamine promotes the reaction [LEP gene mutant form results in increased expression of SPP1 protein]; Galactosamine promotes the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA]; Galactosamine promotes the reaction [LEPR gene mutant form results in increased expression of SPP1 protein]; SPP1 promotes the reaction [LEP gene mutant form results in increased susceptibility to Galactosamine]; SPP1 promotes the reaction [LEPR gene mutant form results in increased susceptibility to Galactosamine] |
CTD |
PMID:19913045 |
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased phosphorylation of STAT3 protein] |
CTD |
PMID:28887131 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Stat5b |
signal transducer and activator of transcription 5B |
decreases activity |
ISO |
Galactosamine results in decreased activity of STAT5B protein |
CTD |
PMID:30114225 |
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NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions |
EXP |
Galactosamine results in increased expression of TGFB1 mRNA; Galactosamine results in increased expression of TGFB1 protein Genistein inhibits the reaction [Galactosamine results in increased expression of TGFB1 mRNA]; Genistein inhibits the reaction [Galactosamine results in increased expression of TGFB1 protein]; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of TGFB1 protein] |
CTD |
PMID:27836788 PMID:27876602 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions |
EXP |
[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of TJP1 mRNA; [Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of TJP1 protein; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of TJP1 mRNA]; Lactulose inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of TJP1 protein]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of TJP1 mRNA]; qingdu inhibits the reaction [[Thioacetamide co-treated with Galactosamine co-treated with Lipopolysaccharides] results in decreased expression of TJP1 protein] |
CTD |
PMID:36414212 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions |
ISO |
[Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TLR4 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TLR4 protein; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TLR4 protein] |
CTD |
PMID:28125915 PMID:32453893 |
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression |
ISO EXP |
2-chloro-5-nitrobenzanilide inhibits the reaction [geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]]; 3-Hydroxybutyric Acid promotes the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF mRNA]; 8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; [Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA; [Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; [Galactosamine co-treated with Lipopolysaccharides] results in increased expression of TNF protein; [lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of and results in increased secretion of TNF protein; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF mRNA; [lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF mRNA; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein; [Methylene Chloride co-treated with Biliverdine] inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; [Nitric Oxide Donors results in increased abundance of Nitric Oxide] inhibits the reaction [[TNF protein co-treated with Galactosamine] results in increased activity of CASP3 protein]; [TNF protein co-treated with Galactosamine] results in increased activity of CASP3 protein; beraprost inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF mRNA]; Berberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF mRNA]; cobaltiprotoporphyrin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; cobaltiprotoporphyrin inhibits the reaction [TNF protein promotes the reaction [Galactosamine results in increased activity of CASP3 protein]]; Dextromethorphan inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF protein]; Dithiothreitol inhibits the reaction [Nitric Oxide Donors inhibits the reaction [[TNF protein co-treated with Galactosamine] results in increased activity of CASP3 protein]]; gentiopicroside inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; geraniol inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of and results in increased secretion of TNF protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] results in increased expression of TNF mRNA]; Hemin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; hydroquinone metabolite inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; Indomethacin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; nilotinib inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; nimesulide inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; ONO 1301 inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of TNF mRNA]; Prednisolone inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF mRNA]; Rotenone inhibits the reaction [[lipopolysaccharide, E coli O55-B5 co-treated with Galactosamine] results in increased expression of TNF protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]; TNF protein promotes the reaction [Galactosamine results in increased activity of CASP3 protein]; zinc protoporphyrin inhibits the reaction [8-oxoberberine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of TNF protein]] Galactosamine results in increased expression of TNF mRNA; Galactosamine results in increased expression of TNF protein [Galactosamine co-treated with TNF protein] results in increased activity of CASP3 protein; Galactosamine analog inhibits the reaction [TNF results in increased expression of ICAM1 protein] [ALB protein co-treated with [Lipopolysaccharides co-treated with Galactosamine]] results in increased expression of TNF protein; Alprostadil promotes the reaction [Galactosamine results in increased expression of TNF protein]; Genistein inhibits the reaction [Galactosamine results in increased expression of TNF protein]; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of TNF mRNA]; glycine propionyl carnitine inhibits the reaction [Galactosamine results in increased expression of TNF protein]; mangiferin inhibits the reaction [Galactosamine results in increased expression of TNF mRNA]; mangiferin inhibits the reaction [Galactosamine results in increased expression of TNF protein] |
CTD |
PMID:9388267 PMID:10221824 PMID:11779202 PMID:14512878 PMID:15135310 PMID:15486963 PMID:16431966 PMID:17602819 PMID:17963606 PMID:20054000 PMID:20558151 PMID:22107987 PMID:22118634 PMID:22310181 PMID:24565947 PMID:24830863 PMID:25620059 PMID:26176423 PMID:27836788 PMID:28125915 PMID:28213090 PMID:28887131 PMID:30550845 PMID:30822415 PMID:31332890 PMID:32453893 PMID:35691465 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]; Glycyrrhetinic Acid inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with Galactosamine] promotes the reaction [TRAF6 protein binds to IRAK1 protein]] |
CTD |
PMID:28213090 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
EXP |
4-phenylbutyric acid inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of VEGFA mRNA]; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of VEGFA mRNA |
CTD |
PMID:28844859 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Xdh |
xanthine dehydrogenase |
increases activity multiple interactions |
EXP |
Galactosamine results in increased activity of XDH protein Vitamin U inhibits the reaction [Galactosamine results in increased activity of XDH protein] |
CTD |
PMID:35673974 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Xiap |
X-linked inhibitor of apoptosis |
multiple interactions |
ISO |
[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of XIAP protein; baicalein inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of XIAP protein]; Silymarin inhibits the reaction [[Galactosamine co-treated with Lipopolysaccharides] results in decreased activity of XIAP protein] |
CTD |
PMID:20850421 |
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NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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G |
Aacs |
acetoacetyl-CoA synthetase |
increases expression |
ISO |
Glucosamine results in increased expression of AACS mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ABCG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Glucosamine results in increased expression of ACACA mRNA |
CTD |
PMID:22096489 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acan |
aggrecan |
multiple interactions increases expression decreases expression affects expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein Glucosamine results in increased expression of ACAN mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA] Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein Glucosamine analog results in decreased expression of ACAN mRNA Glucosamine analog affects the expression of ACAN mRNA |
CTD |
PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 PMID:18321735 PMID:19909832 More...
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NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ACOT1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ACSS2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
multiple interactions decreases expression |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
decreases expression multiple interactions |
ISO EXP |
Glucosamine analog results in decreased expression of ADAMTS1 mRNA Glucosamine results in decreased expression of ADAMTS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA] |
CTD |
PMID:16300972 PMID:17109745 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adamts20 |
ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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G |
Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
EXP |
Glucosamine results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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G |
Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
decreases expression multiple interactions |
ISO |
Glucosamine analog results in decreased expression of ADAMTS5 mRNA Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form |
CTD |
PMID:16300972 PMID:19909832 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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G |
Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO EXP |
Glucosamine results in increased expression of ADIPOQ mRNA |
CTD |
PMID:15694357 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
increases expression |
ISO |
Glucosamine results in increased expression of AFP mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Agt |
angiotensinogen |
increases expression |
ISO |
Glucosamine results in increased expression of AGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahi1 |
Abelson helper integration site 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of AHI1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041
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G |
Akt1 |
AKT serine/threonine kinase 1 |
affects phosphorylation multiple interactions |
ISO |
Glucosamine analog affects the phosphorylation of AKT1 protein Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:18080321 PMID:18340449 PMID:30602124 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of ALG12 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression increases activity |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] Glucosamine analog results in increased expression of ALPL mRNA |
CTD |
PMID:20458730 |
|
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Apoa1 |
apolipoprotein A1 |
increases secretion increases stability |
ISO |
Glucosamine results in increased secretion of APOA1 protein Glucosamine results in increased stability of APOA1 mRNA |
CTD |
PMID:15164326 |
|
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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|
G |
Apob |
apolipoprotein B |
multiple interactions increases degradation increases ubiquitination decreases secretion decreases localization decreases expression |
ISO EXP |
acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein] Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] Glucosamine results in increased ubiquitination of APOB protein Glucosamine results in decreased localization of APOB protein Glucosamine results in decreased expression of APOB protein |
CTD |
PMID:15618547 PMID:19383982 |
|
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] |
CTD |
PMID:16380481 |
|
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf3 |
activating transcription factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATF3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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|
G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression |
ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein |
CTD |
PMID:30602124 PMID:33812996 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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|
G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] Glucosamine results in increased expression of ATF6 protein 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in decreased expression of ATF6 mRNA |
CTD |
PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Glucosamine results in increased expression of ATF7IP mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATP2A2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Azin1 |
antizyme inhibitor 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of AZIN1 mRNA IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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G |
B3gat3 |
beta-1,3-glucuronyltransferase 3 |
multiple interactions increases expression |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] |
CTD |
PMID:11229466 PMID:11801247 |
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NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression multiple interactions |
ISO |
Glucosamine results in decreased expression of BCL2L1 protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein] |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Glucosamine results in decreased expression of BDNF mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
ISO |
Glucosamine analog results in increased expression of BGLAP mRNA |
CTD |
PMID:20458730 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein |
CTD |
PMID:24442997 |
|
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of BMP4 mRNA Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA] Glucosamine results in decreased expression of BMP6 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA] Glucosamine results in increased expression of BMP7 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Glucosamine results in decreased expression of CALR mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Car3 |
carbonic anhydrase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CAR3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of CASP3 protein Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein |
CTD |
PMID:16850161 PMID:22020377 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of CASP4 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Cbr2 |
carbonyl reductase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
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G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein] Glucosamine results in increased expression of CCL2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA] |
CTD |
PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein] Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA] |
CTD |
PMID:17109745 PMID:18080321 |
|
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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|
G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
Glucosamine analog results in increased expression of CCN2 mRNA |
CTD |
PMID:21466783 |
|
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CCNB1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
Glucosamine results in increased expression of CD24A mRNA |
CTD |
PMID:17178593 |
|
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd28 |
Cd28 molecule |
increases expression |
EXP |
Glucosamine results in increased expression of CD28 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cdc20 |
cell division cycle 20 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC20 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc23 |
cell division cycle 23 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC23 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDK1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP ISO |
Glucosamine results in increased expression of CDKN1A protein Glucosamine results in increased expression of CDKN1A mRNA |
CTD |
PMID:15654767 PMID:17178593 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN1B protein |
CTD |
PMID:15654767 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cenpf |
centromere protein F |
decreases expression |
EXP |
Glucosamine results in decreased expression of CENPF mRNA |
CTD |
PMID:17109745 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Chi3l1 |
chitinase 3 like 1 |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of CHI3L1 mRNA |
CTD |
PMID:16142878 |
|
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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|
G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions decreases activity |
ISO |
Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein Glucosamine analog results in decreased activity of CHUK protein |
CTD |
PMID:20113495 |
|
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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G |
Clock |
clock circadian regulator |
decreases expression |
ISO |
Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein |
CTD |
PMID:24442997 |
|
NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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|
G |
Clta |
clathrin, light chain A |
decreases expression |
EXP |
Glucosamine results in decreased expression of CLTA mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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|
G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions decreases expression |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA] Glucosamine results in decreased expression of COL1A1 mRNA |
CTD |
PMID:18321735 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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|
G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions affects expression increases expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA] Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA] Glucosamine analog affects the expression of COL2A1 mRNA Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA |
CTD |
PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
|
|
G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
|
|
G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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|
G |
Csf1 |
colony stimulating factor 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
|
|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA] Glucosamine results in increased expression of CSF2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
|
|
G |
Csf3 |
colony stimulating factor 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA] Glucosamine results in increased expression of CSF3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctsd |
cathepsin D |
affects localization multiple interactions increases activity decreases expression |
ISO |
Glucosamine affects the localization of CTSD protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] Glucosamine results in increased activity of CTSD protein |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Cul2 |
cullin 2 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] |
CTD |
PMID:18173918 |
|
NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO EXP |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA] |
CTD |
PMID:17109745 PMID:20737476 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
EXP |
Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression |
ISO |
Glucosamine results in decreased expression of CYBA mRNA |
CTD |
PMID:18077487 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
Glucosamine affects the localization of CYCS protein |
CTD |
PMID:15972124 PMID:22020377 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
Glucosamine results in increased expression of CYP51 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Glucosamine results in increased expression of DBI mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions decreases expression |
ISO |
Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein] Glucosamine results in decreased expression of DDIT3 mRNA |
CTD |
PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
EXP |
Glucosamine results in increased expression of DDIT4L mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
increases expression |
ISO |
Glucosamine results in increased expression of DHCR7 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dnajb11 |
DnaJ heat shock protein family (Hsp40) member B11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB11 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dspp |
dentin sialophosphoprotein |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of DSPP mRNA |
CTD |
PMID:20458730 |
|
NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA] Glucosamine results in increased expression of DUSP5 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp7 |
dual specificity phosphatase 7 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EDEM1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased expression of EIF2AK3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein] EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO EXP |
Glucosamine results in increased phosphorylation of EIF2S1 protein NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
|
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression |
ISO |
Glucosamine results in increased expression of ELOVL6 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Epas1 |
endothelial PAS domain protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of EPAS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EPRS1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression |
ISO |
ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of FABP4 mRNA |
CTD |
PMID:15694357 |
|
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Glucosamine results in increased expression of FASN mRNA |
CTD |
PMID:22096489 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fbp2 |
fructose-bisphosphatase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of FBP2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
EXP |
Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] |
CTD |
PMID:1518840 |
|
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of FGF7 mRNA IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgf9 |
fibroblast growth factor 9 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA] Glucosamine results in increased expression of FGF9 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA] Glucosamine results in increased expression of FGFR1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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|
G |
Fkbp11 |
FKBP prolyl isomerase 11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of FKBP11 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO EXP |
Glucosamine results in decreased expression of FN1 protein |
CTD |
PMID:17178593 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA] Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein] |
CTD |
PMID:19375915 PMID:21825963 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
Furin |
furin (paired basic amino acid cleaving enzyme) |
decreases cleavage multiple interactions |
ISO |
Glucosamine results in decreased cleavage of FURIN protein alternative form Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein |
CTD |
PMID:19909832 |
|
NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
increases expression |
EXP |
Glucosamine results in increased expression of FXYD2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GATM mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
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G |
Gck |
glucokinase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GCK mRNA |
CTD |
PMID:11893929 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Glucosamine analog results in increased expression of GCLC mRNA |
CTD |
PMID:21825963 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
multiple interactions |
EXP |
[Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein |
CTD |
PMID:9453242 |
|
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
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G |
Glrx |
glutaredoxin |
increases expression |
ISO |
Glucosamine results in increased expression of GLRX mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gnpnat1 |
glucosamine-phosphate N-acetyltransferase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of GNPNAT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
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G |
Gnptab |
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta |
increases expression |
ISO |
Glucosamine results in increased expression of GNPTAB mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
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G |
Gpd1l |
glycerol-3-phosphate dehydrogenase 1 like |
increases expression |
ISO |
Glucosamine results in increased expression of GPD1L mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
ISO |
Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] Glucosamine results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:33812996 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gspt1 |
G1 to S phase transition 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] |
CTD |
PMID:18173918 |
|
NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
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|
G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression |
ISO |
Glucosamine results in increased expression of GSTT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of HAPLN1 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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|
G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HERPUD1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions decreases expression |
ISO |
Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein |
CTD |
PMID:19254699 PMID:22020377 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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|
G |
Hk1 |
hexokinase 1 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of HK1 mRNA |
CTD |
PMID:11893929 PMID:17178593 |
|
NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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|
G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression |
EXP |
Glucosamine results in increased expression of HMGA1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
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|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of HMGCS1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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|
G |
Hmmr |
hyaluronan-mediated motility receptor |
decreases expression |
EXP |
Glucosamine results in decreased expression of HMMR mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein] Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein |
CTD |
PMID:18077487 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hoxa1 |
homeobox A1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HOXA1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
EXP |
Glucosamine results in decreased expression of HPGD mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
decreases expression increases expression |
ISO EXP |
Glucosamine results in decreased expression of HSP90B1 mRNA Glucosamine results in increased expression of HSP90B1 protein |
CTD |
PMID:15618547 PMID:17109745 PMID:17178593 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] Glucosamine results in decreased expression of HSPA5 mRNA |
CTD |
PMID:15618547 PMID:16380481 PMID:17178593 PMID:19383982 PMID:20165829 PMID:22020377 PMID:30602124 PMID:33812996 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hyou1 |
hypoxia up-regulated 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HYOU1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions decreases activity |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] Glucosamine results in decreased activity of ICAM1 protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 PMID:16822504 PMID:17238806 PMID:18949387 PMID:19020780 PMID:19098112 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ID1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ID2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
Glucosamine results in increased expression of ID3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
increases expression |
ISO |
Glucosamine results in increased expression of IDH1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
increases expression |
ISO |
Glucosamine results in increased expression of IFIT3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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G |
Ifng |
interferon gamma |
decreases secretion multiple interactions |
ISO |
Glucosamine results in decreased secretion of IFNG protein Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]] |
CTD |
PMID:14507305 PMID:16431966 PMID:16822504 PMID:17238806 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA] Glucosamine results in decreased expression of IGFBP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA] Glucosamine results in increased expression of IGFBP5 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] |
CTD |
PMID:18786831 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il11 |
interleukin 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA] Glucosamine results in decreased expression of IL13RA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Glucosamine results in increased expression of IL1B mRNA Glucosamine results in decreased expression of IL1B mRNA [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
CTD |
PMID:11229466 PMID:11801247 PMID:12681956 PMID:15144122 PMID:16822504 PMID:17109745 PMID:17238806 PMID:17337215 PMID:17605605 PMID:17925024 PMID:18026701 PMID:18077487 PMID:18080321 PMID:18321735 PMID:18340449 PMID:18786831 PMID:19626664 PMID:19656660 PMID:20737476 PMID:21219853 PMID:22089456 PMID:38437956 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions |
EXP |
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA |
CTD |
PMID:11801247 |
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NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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G |
Il2 |
interleukin 2 |
decreases secretion |
ISO |
Glucosamine results in decreased secretion of IL2 protein |
CTD |
PMID:14507305 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il23r |
interleukin 23 receptor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
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G |
Il33 |
interleukin 33 |
decreases expression |
EXP |
Glucosamine results in decreased expression of IL33 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL4 protein Glucosamine results in decreased expression of IL4 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL5 protein Glucosamine results in decreased expression of IL5 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
CTD |
PMID:16822504 PMID:17109745 PMID:18786831 PMID:19098112 PMID:20093129 PMID:20113495 PMID:20307528 PMID:20737476 PMID:38437956 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Inpp5k |
inositol polyphosphate-5-phosphatase K |
multiple interactions increases expression |
ISO |
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA] |
CTD |
PMID:33812996 |
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NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein; Glucosamine inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]] [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:9453242 PMID:11893929 PMID:16380481 PMID:20165829 PMID:30602124 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] |
CTD |
PMID:20165829 PMID:33812996 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] |
CTD |
PMID:20737476 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Isyna1 |
inositol-3-phosphate synthase 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ISYNA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression |
EXP ISO |
Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein |
CTD |
PMID:17109745 PMID:38437956 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein] Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA] |
CTD |
PMID:17925024 PMID:21825963 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] |
CTD |
PMID:17925024 |
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NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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G |
Kcnj16 |
potassium inwardly-rectifying channel, subfamily J, member 16 |
increases expression |
ISO |
Glucosamine results in increased expression of KCNJ16 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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G |
Kif11 |
kinesin family member 11 |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF11 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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G |
Kif4a |
kinesin family member 4A |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF4A mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139
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G |
Klf10 |
KLF transcription factor 10 |
increases expression |
ISO |
Glucosamine results in increased expression of KLF10 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Lama4 |
laminin subunit alpha 4 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc1 |
laminin subunit gamma 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lcn2 |
lipocalin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of LCN2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lepr |
leptin receptor |
affects response to substance multiple interactions |
EXP |
LEPR protein affects the susceptibility to Glucosamine [LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lpin1 |
lipin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of LPIN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Ly6a |
lymphocyte antigen 6 family member A |
increases expression |
ISO |
Glucosamine results in increased expression of LY6A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981
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G |
Mafb |
MAF bZIP transcription factor B |
increases expression |
EXP |
Glucosamine results in increased expression of MAFB mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] Glucosamine analog results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:19626664 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] Glucosamine analog results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] Glucosamine analog results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:18080321 PMID:19626664 PMID:20307528 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein |
CTD |
PMID:22020377 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein] Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein |
CTD |
PMID:20165829 |
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NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
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G |
Mettl1 |
methyltransferase 1, tRNA methylguanosine |
decreases expression |
ISO |
Glucosamine results in decreased expression of METTL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202
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G |
Mfap3l |
microfibril associated protein 3 like |
increases expression |
ISO |
Glucosamine results in increased expression of MFAP3L mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
EXP |
Glucosamine results in decreased expression of MKI67 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] |
CTD |
PMID:15144122 PMID:17925024 PMID:18080321 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp10 |
matrix metallopeptidase 10 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of MMP10 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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G |
Mmp12 |
matrix metallopeptidase 12 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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G |
Mmp13 |
matrix metallopeptidase 13 |
affects expression multiple interactions increases expression |
ISO EXP |
Glucosamine analog affects the expression of MMP13 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA] Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein] |
CTD |
PMID:15144122 PMID:17109745 PMID:17337215 PMID:17925024 PMID:18080321 PMID:19656660 More...
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein] IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein Glucosamine results in increased expression of MMP3 mRNA Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA] Glucosamine analog results in decreased expression of MMP3 mRNA |
CTD |
PMID:11229466 PMID:12801482 PMID:15144122 PMID:16300972 PMID:17109745 PMID:17925024 PMID:18080321 PMID:18340449 PMID:20110869 More...
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein] Glucosamine results in increased expression of MMP9 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mnda |
myeloid cell nuclear differentiation antigen |
increases expression |
ISO |
Glucosamine results in increased expression of IFI204 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
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G |
Mpo |
myeloperoxidase |
decreases activity |
EXP |
Glucosamine results in decreased activity of MPO protein |
CTD |
PMID:19098112 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mvd |
mevalonate diphosphate decarboxylase |
increases expression |
ISO |
Glucosamine results in increased expression of MVD mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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G |
Ndufa4 |
Ndufa4, mitochondrial complex associated |
increases expression |
EXP |
Glucosamine results in increased expression of NDUFA4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
decreases expression |
EXP |
Glucosamine results in decreased expression of NEDD4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases activity |
ISO EXP |
Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein] Glucosamine results in decreased activity of NFKB1 protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein] |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17498959 PMID:18036590 PMID:18205790 PMID:20737476 More...
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases phosphorylation decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] Glucosamine results in decreased phosphorylation of NFKBIA protein Glucosamine results in decreased expression of NFKBIA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:12681956 PMID:17109745 PMID:18080321 PMID:18205790 PMID:19098112 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Ngef |
neuronal guanine nucleotide exchange factor |
increases expression |
ISO |
Glucosamine results in increased expression of NGEF mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] Glucosamine results in increased expression of NOS2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA] Glucosamine results in decreased expression of NOS2 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:17109745 PMID:17440993 PMID:17605605 PMID:18077487 PMID:18205790 PMID:19098112 PMID:20737476 PMID:38437956 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Glucosamine affects the expression of NR1H4 |
CTD |
PMID:19373748 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
ISO |
Glucosamine results in increased expression of NSDHL mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G |
Nucb2 |
nucleobindin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of NUCB2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
EXP |
Glucosamine results in decreased expression of NUF2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of OGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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G |
Orc2 |
origin recognition complex, subunit 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ORC2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195
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G |
Osm |
oncostatin M |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] |
CTD |
PMID:21219853 |
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NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
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G |
Ostn |
osteocrin |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of OSTN mRNA 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:30602124 |
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NCBI chr11:73,442,167...73,478,498
Ensembl chr11:73,442,487...73,468,603
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G |
Oxr1 |
oxidation resistance 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of OXR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666
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G |
Pank1 |
pantothenate kinase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of PANK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of PARP1 protein pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] |
CTD |
PMID:16850161 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PDGFA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA] |
CTD |
PMID:17109745 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pdia6 |
protein disulfide isomerase family A, member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of PDK4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pfkp |
phosphofructokinase, platelet |
increases expression |
ISO |
Glucosamine results in increased expression of PFKP mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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G |
Piga |
phosphatidylinositol glycan anchor biosynthesis, class A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PIGA mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
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G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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G |
Pla2g4a |
phospholipase A2 group 4A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PLA2G4A mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Pla2g5 |
phospholipase A2, group V |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Glucosamine results in increased expression of PLAT mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plk1 |
polo-like kinase 1 |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of PLK1 mRNA Glucosamine results in decreased expression of PLK1 mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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G |
Plpp3 |
phospholipid phosphatase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PLPP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO EXP |
Glucosamine promotes the reaction [IL1B results in increased expression of PPARG] Glucosamine results in increased expression of PPARG mRNA |
CTD |
PMID:15694357 PMID:22089456 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein |
CTD |
PMID:20165829 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppm1a |
protein phosphatase, Mg2+/Mn2+ dependent, 1A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPM1A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Prc1 |
protein regulator of cytokinesis 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PRC1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Psme3 |
proteasome activator subunit 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PSME3 |
CTD |
PMID:21697645 |
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NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
ISO |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] |
CTD |
PMID:17605605 PMID:22089456 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression decreases expression multiple interactions decreases glycosylation |
ISO EXP |
Glucosamine analog results in increased expression of PTGS2 protein alternative form Glucosamine results in decreased expression of PTGS2 mRNA Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] Glucosamine results in decreased glycosylation of PTGS2 protein [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:12681956 PMID:17440993 PMID:17605605 PMID:18205790 PMID:19656660 PMID:20737476 PMID:22089456 PMID:38437956 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
decreases expression |
EXP |
Glucosamine results in decreased expression of PTTG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Rab32 |
RAB32, member RAS oncogene family |
increases expression |
ISO |
Glucosamine results in increased expression of RAB32 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
ISO |
Glucosamine results in decreased expression of RBM39 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
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G |
Recql4 |
RecQ like helicase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of RECQL4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity increases localization |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein] Glucosamine results in decreased activity of RELA protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] Glucosamine results in increased localization of RELA protein |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17238806 PMID:17498959 PMID:18036590 PMID:18080321 PMID:18205790 PMID:18340449 PMID:18786831 PMID:19020780 PMID:19375915 PMID:20307528 PMID:20737476 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Relb |
RELB proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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G |
Rhob |
ras homolog family member B |
increases expression |
ISO |
Glucosamine results in increased expression of RHOB mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Rhoc |
ras homolog family member C |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of RHOC mRNA |
CTD |
PMID:16142878 |
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NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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G |
Rnd1 |
Rho family GTPase 1 |
multiple interactions decreases expression |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA] Glucosamine results in decreased expression of RND1 mRNA |
CTD |
PMID:17178593 PMID:18173918 |
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NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:19254699 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6KB1 protein |
CTD |
PMID:19254699 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Runx2 |
RUNX family transcription factor 2 |
increases phosphorylation increases expression multiple interactions |
ISO |
Glucosamine analog results in increased phosphorylation of RUNX2 protein Glucosamine analog results in increased expression of RUNX2 mRNA 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] |
CTD |
PMID:20458730 |
|
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of SCD2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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G |
Sdc2 |
syndecan 2 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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G |
Sdc4 |
syndecan 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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G |
Selenbp1 |
selenium binding protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SELENBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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Serpinb2 |
serpin family B member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SERPINB2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpinh1 |
serpin family H member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SERPINH1 protein |
CTD |
PMID:16380481 |
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NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SFRP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Sgk1 |
serum/glucocorticoid regulated kinase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SGK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Shcbp1 |
SHC binding and spindle associated 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SHCBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
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Slc17a1 |
solute carrier family 17 member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC17A1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
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Slc23a2 |
solute carrier family 23 member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SLC23A2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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Slc2a2 |
solute carrier family 2 member 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC2A2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions decreases expression increases uptake |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein] Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein SLC2A4 protein results in increased uptake of Glucosamine Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine] |
CTD |
PMID:19373748 PMID:20165829 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc2a6 |
solute carrier family 2 member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SLC2A6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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Slc37a4 |
solute carrier family 37 member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC37A4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
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Slc4a4 |
solute carrier family 4 member 4 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC4A4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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Slc7a8 |
solute carrier family 7 member 8 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of SLC7A8 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr15:28,183,013...28,242,717
Ensembl chr15:28,183,015...28,242,717
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G |
Smad2 |
SMAD family member 2 |
multiple interactions increases phosphorylation |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:20458730 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smpd3 |
sphingomyelin phosphodiesterase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SMPD3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
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G |
Sox4 |
SRY-box transcription factor 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA] Glucosamine results in decreased expression of SOX4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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G |
Srsf3 |
serine and arginine rich splicing factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SRSF3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
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G |
St6gal1 |
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ST6GAL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] |
CTD |
PMID:16431966 PMID:17238806 |
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NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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G |
Tacc3 |
transforming, acidic coiled-coil containing protein 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TACC3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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G |
Testin |
testin gene |
decreases expression |
EXP |
Glucosamine results in decreased expression of TESTIN mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions |
EXP |
[Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] |
CTD |
PMID:1518840 |
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NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Tgfb1 |
transforming growth factor, beta 1 |
increases expression |
EXP |
Glucosamine analog results in increased expression of TGFB1 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1 |
transforming growth factor, beta receptor 1 |
increases expression multiple interactions |
ISO |
Glucosamine analog results in increased expression of TGFBR1 protein 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein] |
CTD |
PMID:20458730 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Thbs4 |
thrombospondin 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of TIMP2 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
multiple interactions increases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA Glucosamine results in increased expression of TIMP3 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA] |
CTD |
PMID:17109745 PMID:17605605 |
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NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Tinag |
tubulointerstitial nephritis antigen |
increases expression |
ISO |
Glucosamine results in increased expression of TINAG mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
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G |
Tk1 |
thymidine kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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G |
Tlr1 |
toll-like receptor 1 |
increases expression |
ISO |
Glucosamine results in increased expression of TLR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
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Tnf |
tumor necrosis factor |
decreases secretion multiple interactions decreases expression |
ISO EXP |
Glucosamine results in decreased secretion of TNF protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] [Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
CTD |
PMID:14507305 PMID:16431966 PMID:16445576 PMID:16822504 PMID:17238806 PMID:18173918 PMID:18205790 PMID:18786831 PMID:19020780 PMID:19098112 PMID:20093129 PMID:20110869 PMID:20113495 PMID:20737476 PMID:38437956 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip6 |
TNF alpha induced protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfrsf11b |
TNF receptor superfamily member 11B |
multiple interactions |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein |
CTD |
PMID:17996099 |
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NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions increases expression |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] |
CTD |
PMID:17996099 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Tnk2 |
tyrosine kinase, non-receptor, 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009
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G |
Top2a |
DNA topoisomerase II alpha |
decreases expression |
EXP |
Glucosamine results in decreased expression of TOP2A mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of TRPV4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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Txn1 |
thioredoxin 1 |
decreases expression |
EXP ISO |
Glucosamine results in decreased expression of TXN1 protein |
CTD |
PMID:17178593 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
EXP ISO |
Glucosamine results in increased expression of TXNIP protein Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Ucp2 |
uncoupling protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of UCP2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
increases expression |
ISO |
Glucosamine results in increased expression of UQCRH mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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Vamp1 |
vesicle-associated membrane protein 1 |
increases expression |
EXP |
Glucosamine results in increased expression of VAMP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349
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Vcan |
versican |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression decreases expression |
ISO EXP |
Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein] Glucosamine results in increased expression of VEGFA protein Glucosamine results in decreased expression of VEGFA protein |
CTD |
PMID:16324875 PMID:19254699 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfd |
vascular endothelial growth factor D |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of VEGFD mRNA Glucosamine results in decreased expression of VEGFD mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Vnn1 |
vanin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of VNN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions increases splicing increases expression decreases splicing |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] Glucosamine results in decreased splicing of XBP1 mRNA |
CTD |
PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] |
CTD |
PMID:11801247 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
Glucosamine results in increased expression of ZFP467 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of CEBPA protein |
CTD |
PMID:19427183 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of DLK1 mRNA |
CTD |
PMID:19427183 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of FABP4 mRNA |
CTD |
PMID:19427183 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of FAS mRNA |
CTD |
PMID:19427183 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
increases abundance multiple interactions |
ISO |
IDH2 protein mutant form results in increased abundance of glucosamine 6-phosphate Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glucosamine 6-phosphate] |
CTD |
PMID:27469509 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Lep |
leptin |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of LEP mRNA |
CTD |
PMID:19427183 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipe |
lipase E, hormone sensitive type |
increases expression |
ISO |
glucosamine 6-phosphate results in increased expression of LIPE mRNA |
CTD |
PMID:19427183 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Lpl |
lipoprotein lipase |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of LPL mRNA |
CTD |
PMID:19427183 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of PPARG protein |
CTD |
PMID:19427183 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of SREBF1 protein |
CTD |
PMID:19427183 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Tnf |
tumor necrosis factor |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of TNF mRNA |
CTD |
PMID:19427183 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Aacs |
acetoacetyl-CoA synthetase |
increases expression |
ISO |
Glucosamine results in increased expression of AACS mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ABCG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Glucosamine results in increased expression of ACACA mRNA |
CTD |
PMID:22096489 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acan |
aggrecan |
multiple interactions increases expression decreases expression affects expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein Glucosamine results in increased expression of ACAN mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA] Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein Glucosamine analog results in decreased expression of ACAN mRNA Glucosamine analog affects the expression of ACAN mRNA |
CTD |
PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 PMID:18321735 PMID:19909832 More...
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NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ACOT1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ACSS2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
multiple interactions decreases expression |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
decreases expression multiple interactions |
ISO EXP |
Glucosamine analog results in decreased expression of ADAMTS1 mRNA Glucosamine results in decreased expression of ADAMTS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA] |
CTD |
PMID:16300972 PMID:17109745 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adamts20 |
ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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G |
Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
EXP |
Glucosamine results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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G |
Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
decreases expression multiple interactions |
ISO |
Glucosamine analog results in decreased expression of ADAMTS5 mRNA Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form |
CTD |
PMID:16300972 PMID:19909832 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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G |
Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO EXP |
Glucosamine results in increased expression of ADIPOQ mRNA |
CTD |
PMID:15694357 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
increases expression |
ISO |
Glucosamine results in increased expression of AFP mRNA |
CTD |
PMID:17178593 |
|
NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Agt |
angiotensinogen |
increases expression |
ISO |
Glucosamine results in increased expression of AGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahi1 |
Abelson helper integration site 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of AHI1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041
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G |
Akt1 |
AKT serine/threonine kinase 1 |
affects phosphorylation multiple interactions |
ISO |
Glucosamine analog affects the phosphorylation of AKT1 protein Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:18080321 PMID:18340449 PMID:30602124 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of ALG12 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression increases activity |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] Glucosamine analog results in increased expression of ALPL mRNA |
CTD |
PMID:20458730 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Apoa1 |
apolipoprotein A1 |
increases secretion increases stability |
ISO |
Glucosamine results in increased secretion of APOA1 protein Glucosamine results in increased stability of APOA1 mRNA |
CTD |
PMID:15164326 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apob |
apolipoprotein B |
multiple interactions increases degradation increases ubiquitination decreases secretion decreases localization decreases expression |
ISO EXP |
acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein] Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] Glucosamine results in increased ubiquitination of APOB protein Glucosamine results in decreased localization of APOB protein Glucosamine results in decreased expression of APOB protein |
CTD |
PMID:15618547 PMID:19383982 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] |
CTD |
PMID:16380481 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf3 |
activating transcription factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATF3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in increased expression of ATF6 protein ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in decreased expression of ATF6 mRNA |
CTD |
PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Glucosamine results in increased expression of ATF7IP mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATP2A2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Azin1 |
antizyme inhibitor 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of AZIN1 mRNA IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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G |
B3gat3 |
beta-1,3-glucuronyltransferase 3 |
multiple interactions increases expression |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] |
CTD |
PMID:11229466 PMID:11801247 |
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NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression multiple interactions |
ISO |
Glucosamine results in decreased expression of BCL2L1 protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein] |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Glucosamine results in decreased expression of BDNF mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
ISO |
Glucosamine analog results in increased expression of BGLAP mRNA |
CTD |
PMID:20458730 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein |
CTD |
PMID:24442997 |
|
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of BMP4 mRNA Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA] Glucosamine results in decreased expression of BMP6 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA] Glucosamine results in increased expression of BMP7 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Glucosamine results in decreased expression of CALR mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Car3 |
carbonic anhydrase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CAR3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of CASP3 protein Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein |
CTD |
PMID:16850161 PMID:22020377 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of CASP4 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Cbr2 |
carbonyl reductase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
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G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein] Glucosamine results in increased expression of CCL2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA] |
CTD |
PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein] Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA] |
CTD |
PMID:17109745 PMID:18080321 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
Glucosamine analog results in increased expression of CCN2 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccnb1 |
cyclin B1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CCNB1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Cd24 |
CD24 molecule |
increases expression |
ISO |
Glucosamine results in increased expression of CD24A mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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Cd28 |
Cd28 molecule |
increases expression |
EXP |
Glucosamine results in increased expression of CD28 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cdc20 |
cell division cycle 20 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC20 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc23 |
cell division cycle 23 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC23 mRNA |
CTD |
PMID:17109745 |
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NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP ISO |
Glucosamine results in increased expression of CDKN1A protein Glucosamine results in increased expression of CDKN1A mRNA |
CTD |
PMID:15654767 PMID:17178593 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN1B protein |
CTD |
PMID:15654767 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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Cenpf |
centromere protein F |
decreases expression |
EXP |
Glucosamine results in decreased expression of CENPF mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Chi3l1 |
chitinase 3 like 1 |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of CHI3L1 mRNA |
CTD |
PMID:16142878 |
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NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions decreases activity |
ISO |
Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein Glucosamine analog results in decreased activity of CHUK protein |
CTD |
PMID:20113495 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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Clock |
clock circadian regulator |
decreases expression |
ISO |
Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein |
CTD |
PMID:24442997 |
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NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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Clta |
clathrin, light chain A |
decreases expression |
EXP |
Glucosamine results in decreased expression of CLTA mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions decreases expression |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA] Glucosamine results in decreased expression of COL1A1 mRNA |
CTD |
PMID:18321735 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions affects expression increases expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA] Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA] Glucosamine analog affects the expression of COL2A1 mRNA Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA |
CTD |
PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 |
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NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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G |
Csf1 |
colony stimulating factor 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA] Glucosamine results in increased expression of CSF2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA] Glucosamine results in increased expression of CSF3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctsd |
cathepsin D |
affects localization multiple interactions increases activity decreases expression |
ISO |
Glucosamine affects the localization of CTSD protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] Glucosamine results in increased activity of CTSD protein |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Cul2 |
cullin 2 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO EXP |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA] |
CTD |
PMID:17109745 PMID:20737476 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
EXP |
Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression |
ISO |
Glucosamine results in decreased expression of CYBA mRNA |
CTD |
PMID:18077487 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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Cycs |
cytochrome c, somatic |
affects localization |
ISO |
Glucosamine affects the localization of CYCS protein |
CTD |
PMID:15972124 PMID:22020377 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
Glucosamine results in increased expression of CYP51 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Glucosamine results in increased expression of DBI mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions decreases expression |
ISO |
Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein] Glucosamine results in decreased expression of DDIT3 mRNA |
CTD |
PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
EXP |
Glucosamine results in increased expression of DDIT4L mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
increases expression |
ISO |
Glucosamine results in increased expression of DHCR7 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dnajb11 |
DnaJ heat shock protein family (Hsp40) member B11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB11 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dspp |
dentin sialophosphoprotein |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of DSPP mRNA |
CTD |
PMID:20458730 |
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NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA] Glucosamine results in increased expression of DUSP5 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp7 |
dual specificity phosphatase 7 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EDEM1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased expression of EIF2AK3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein] EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO EXP |
Glucosamine results in increased phosphorylation of EIF2S1 protein NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression |
ISO |
Glucosamine results in increased expression of ELOVL6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Epas1 |
endothelial PAS domain protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of EPAS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EPRS1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression |
ISO |
ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] Glucosamine results in increased expression of ERN1 mRNA NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of FABP4 mRNA |
CTD |
PMID:15694357 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Glucosamine results in increased expression of FASN mRNA |
CTD |
PMID:22096489 |
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fbp2 |
fructose-bisphosphatase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of FBP2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
EXP |
Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] |
CTD |
PMID:1518840 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of FGF7 mRNA IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgf9 |
fibroblast growth factor 9 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA] Glucosamine results in increased expression of FGF9 mRNA |
CTD |
PMID:17109745 |
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NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA] Glucosamine results in increased expression of FGFR1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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G |
Fkbp11 |
FKBP prolyl isomerase 11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of FKBP11 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO EXP |
Glucosamine results in decreased expression of FN1 protein |
CTD |
PMID:17178593 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA] Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein] |
CTD |
PMID:19375915 PMID:21825963 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Furin |
furin (paired basic amino acid cleaving enzyme) |
decreases cleavage multiple interactions |
ISO |
Glucosamine results in decreased cleavage of FURIN protein alternative form Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein |
CTD |
PMID:19909832 |
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NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
increases expression |
EXP |
Glucosamine results in increased expression of FXYD2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GATM mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
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G |
Gck |
glucokinase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GCK mRNA |
CTD |
PMID:11893929 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Glucosamine analog results in increased expression of GCLC mRNA |
CTD |
PMID:21825963 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
multiple interactions |
EXP |
[Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein |
CTD |
PMID:9453242 |
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NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
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G |
Glrx |
glutaredoxin |
increases expression |
ISO |
Glucosamine results in increased expression of GLRX mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gnpnat1 |
glucosamine-phosphate N-acetyltransferase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of GNPNAT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
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G |
Gnptab |
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta |
increases expression |
ISO |
Glucosamine results in increased expression of GNPTAB mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
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G |
Gpd1l |
glycerol-3-phosphate dehydrogenase 1 like |
increases expression |
ISO |
Glucosamine results in increased expression of GPD1L mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases phosphorylation multiple interactions |
ISO |
Glucosamine results in decreased phosphorylation of GSK3B protein Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gspt1 |
G1 to S phase transition 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
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G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression |
ISO |
Glucosamine results in increased expression of GSTT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of HAPLN1 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HERPUD1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions decreases expression |
ISO |
Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein |
CTD |
PMID:19254699 PMID:22020377 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hk1 |
hexokinase 1 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of HK1 mRNA |
CTD |
PMID:11893929 PMID:17178593 |
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NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression |
EXP |
Glucosamine results in increased expression of HMGA1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of HMGCS1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmmr |
hyaluronan-mediated motility receptor |
decreases expression |
EXP |
Glucosamine results in decreased expression of HMMR mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein] Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein |
CTD |
PMID:18077487 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hoxa1 |
homeobox A1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HOXA1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
EXP |
Glucosamine results in decreased expression of HPGD mRNA |
CTD |
PMID:17109745 |
|
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
decreases expression increases expression |
ISO EXP |
Glucosamine results in decreased expression of HSP90B1 mRNA Glucosamine results in increased expression of HSP90B1 protein |
CTD |
PMID:15618547 PMID:17109745 PMID:17178593 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein] Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] Glucosamine results in decreased expression of HSPA5 mRNA |
CTD |
PMID:15618547 PMID:16380481 PMID:17178593 PMID:19383982 PMID:20165829 PMID:22020377 PMID:30602124 PMID:33812996 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hyou1 |
hypoxia up-regulated 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HYOU1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions decreases activity |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] Glucosamine results in decreased activity of ICAM1 protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 PMID:16822504 PMID:17238806 PMID:18949387 PMID:19020780 PMID:19098112 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ID1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ID2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
Glucosamine results in increased expression of ID3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
increases expression |
ISO |
Glucosamine results in increased expression of IDH1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
increases expression |
ISO |
Glucosamine results in increased expression of IFIT3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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G |
Ifng |
interferon gamma |
decreases secretion multiple interactions |
ISO |
Glucosamine results in decreased secretion of IFNG protein Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]] |
CTD |
PMID:14507305 PMID:16431966 PMID:16822504 PMID:17238806 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA] Glucosamine results in decreased expression of IGFBP3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA] Glucosamine results in increased expression of IGFBP5 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] |
CTD |
PMID:18786831 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il11 |
interleukin 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA] Glucosamine results in decreased expression of IL13RA1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Glucosamine results in increased expression of IL1B mRNA Glucosamine results in decreased expression of IL1B mRNA [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
CTD |
PMID:11229466 PMID:11801247 PMID:12681956 PMID:15144122 PMID:16822504 PMID:17109745 PMID:17238806 PMID:17337215 PMID:17605605 PMID:17925024 PMID:18026701 PMID:18077487 PMID:18080321 PMID:18321735 PMID:18340449 PMID:18786831 PMID:19626664 PMID:19656660 PMID:20737476 PMID:21219853 PMID:22089456 PMID:38437956 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions |
EXP |
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA |
CTD |
PMID:11801247 |
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NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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G |
Il2 |
interleukin 2 |
decreases secretion |
ISO |
Glucosamine results in decreased secretion of IL2 protein |
CTD |
PMID:14507305 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il23r |
interleukin 23 receptor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
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G |
Il33 |
interleukin 33 |
decreases expression |
EXP |
Glucosamine results in decreased expression of IL33 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL4 protein Glucosamine results in decreased expression of IL4 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL5 protein Glucosamine results in decreased expression of IL5 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
CTD |
PMID:16822504 PMID:17109745 PMID:18786831 PMID:19098112 PMID:20093129 PMID:20113495 PMID:20307528 PMID:20737476 PMID:38437956 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Inpp5k |
inositol polyphosphate-5-phosphatase K |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of INPP5K mRNA NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA] |
CTD |
PMID:33812996 |
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NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein; Glucosamine inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]] [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:9453242 PMID:11893929 PMID:16380481 PMID:20165829 PMID:30602124 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] |
CTD |
PMID:20165829 PMID:33812996 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] |
CTD |
PMID:20737476 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Isyna1 |
inositol-3-phosphate synthase 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ISYNA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression |
EXP ISO |
Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein |
CTD |
PMID:17109745 PMID:38437956 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein] Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA] |
CTD |
PMID:17925024 PMID:21825963 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] |
CTD |
PMID:17925024 |
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NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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G |
Kcnj16 |
potassium inwardly-rectifying channel, subfamily J, member 16 |
increases expression |
ISO |
Glucosamine results in increased expression of KCNJ16 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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G |
Kif11 |
kinesin family member 11 |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF11 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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G |
Kif4a |
kinesin family member 4A |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF4A mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139
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G |
Klf10 |
KLF transcription factor 10 |
increases expression |
ISO |
Glucosamine results in increased expression of KLF10 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Lama4 |
laminin subunit alpha 4 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc1 |
laminin subunit gamma 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lcn2 |
lipocalin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of LCN2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lepr |
leptin receptor |
multiple interactions affects response to substance |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lpin1 |
lipin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of LPIN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Ly6a |
lymphocyte antigen 6 family member A |
increases expression |
ISO |
Glucosamine results in increased expression of LY6A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981
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G |
Mafb |
MAF bZIP transcription factor B |
increases expression |
EXP |
Glucosamine results in increased expression of MAFB mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] Glucosamine analog results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:19626664 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] Glucosamine analog results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] Glucosamine analog results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:18080321 PMID:19626664 PMID:20307528 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein |
CTD |
PMID:22020377 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein] Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein |
CTD |
PMID:20165829 |
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NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
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G |
Mettl1 |
methyltransferase 1, tRNA methylguanosine |
decreases expression |
ISO |
Glucosamine results in decreased expression of METTL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202
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G |
Mfap3l |
microfibril associated protein 3 like |
increases expression |
ISO |
Glucosamine results in increased expression of MFAP3L mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
EXP |
Glucosamine results in decreased expression of MKI67 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] |
CTD |
PMID:15144122 PMID:17925024 PMID:18080321 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp10 |
matrix metallopeptidase 10 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of MMP10 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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G |
Mmp12 |
matrix metallopeptidase 12 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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G |
Mmp13 |
matrix metallopeptidase 13 |
affects expression multiple interactions increases expression |
ISO EXP |
Glucosamine analog affects the expression of MMP13 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA] Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein] |
CTD |
PMID:15144122 PMID:17109745 PMID:17337215 PMID:17925024 PMID:18080321 PMID:19656660 More...
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein] IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein Glucosamine results in increased expression of MMP3 mRNA Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA] Glucosamine analog results in decreased expression of MMP3 mRNA |
CTD |
PMID:11229466 PMID:12801482 PMID:15144122 PMID:16300972 PMID:17109745 PMID:17925024 PMID:18080321 PMID:18340449 PMID:20110869 More...
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein] Glucosamine results in increased expression of MMP9 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mnda |
myeloid cell nuclear differentiation antigen |
increases expression |
ISO |
Glucosamine results in increased expression of IFI204 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
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G |
Mpo |
myeloperoxidase |
decreases activity |
EXP |
Glucosamine results in decreased activity of MPO protein |
CTD |
PMID:19098112 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mvd |
mevalonate diphosphate decarboxylase |
increases expression |
ISO |
Glucosamine results in increased expression of MVD mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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G |
Ndufa4 |
Ndufa4, mitochondrial complex associated |
increases expression |
EXP |
Glucosamine results in increased expression of NDUFA4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
decreases expression |
EXP |
Glucosamine results in decreased expression of NEDD4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases activity |
ISO EXP |
Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein] Glucosamine results in decreased activity of NFKB1 protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein] |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17498959 PMID:18036590 PMID:18205790 PMID:20737476 More...
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases phosphorylation decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] Glucosamine results in decreased phosphorylation of NFKBIA protein Glucosamine results in decreased expression of NFKBIA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:12681956 PMID:17109745 PMID:18080321 PMID:18205790 PMID:19098112 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Ngef |
neuronal guanine nucleotide exchange factor |
increases expression |
ISO |
Glucosamine results in increased expression of NGEF mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] Glucosamine results in increased expression of NOS2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA] Glucosamine results in decreased expression of NOS2 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:17109745 PMID:17440993 PMID:17605605 PMID:18077487 PMID:18205790 PMID:19098112 PMID:20737476 PMID:38437956 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Glucosamine affects the expression of NR1H4 |
CTD |
PMID:19373748 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
ISO |
Glucosamine results in increased expression of NSDHL mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G |
Nucb2 |
nucleobindin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of NUCB2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
EXP |
Glucosamine results in decreased expression of NUF2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of OGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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G |
Orc2 |
origin recognition complex, subunit 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ORC2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195
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G |
Osm |
oncostatin M |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] |
CTD |
PMID:21219853 |
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NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
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G |
Ostn |
osteocrin |
multiple interactions increases expression |
ISO |
4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:30602124 |
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NCBI chr11:73,442,167...73,478,498
Ensembl chr11:73,442,487...73,468,603
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G |
Oxr1 |
oxidation resistance 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of OXR1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666
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G |
Pank1 |
pantothenate kinase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of PANK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of PARP1 protein pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] |
CTD |
PMID:16850161 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PDGFA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA] |
CTD |
PMID:17109745 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pdia6 |
protein disulfide isomerase family A, member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA6 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of PDK4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pfkp |
phosphofructokinase, platelet |
increases expression |
ISO |
Glucosamine results in increased expression of PFKP mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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G |
Piga |
phosphatidylinositol glycan anchor biosynthesis, class A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PIGA mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
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G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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G |
Pla2g4a |
phospholipase A2 group 4A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PLA2G4A mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Pla2g5 |
phospholipase A2, group V |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Glucosamine results in increased expression of PLAT mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plk1 |
polo-like kinase 1 |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of PLK1 mRNA Glucosamine results in decreased expression of PLK1 mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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G |
Plpp3 |
phospholipid phosphatase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PLPP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO EXP |
Glucosamine promotes the reaction [IL1B results in increased expression of PPARG] Glucosamine results in increased expression of PPARG mRNA |
CTD |
PMID:15694357 PMID:22089456 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein |
CTD |
PMID:20165829 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppm1a |
protein phosphatase, Mg2+/Mn2+ dependent, 1A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPM1A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Prc1 |
protein regulator of cytokinesis 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PRC1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Psme3 |
proteasome activator subunit 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PSME3 |
CTD |
PMID:21697645 |
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NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
ISO |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] |
CTD |
PMID:17605605 PMID:22089456 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression decreases expression multiple interactions decreases glycosylation |
ISO EXP |
Glucosamine analog results in increased expression of PTGS2 protein alternative form Glucosamine results in decreased expression of PTGS2 mRNA Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] Glucosamine results in decreased glycosylation of PTGS2 protein [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:12681956 PMID:17440993 PMID:17605605 PMID:18205790 PMID:19656660 PMID:20737476 PMID:22089456 PMID:38437956 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
decreases expression |
EXP |
Glucosamine results in decreased expression of PTTG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Rab32 |
RAB32, member RAS oncogene family |
increases expression |
ISO |
Glucosamine results in increased expression of RAB32 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
ISO |
Glucosamine results in decreased expression of RBM39 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
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G |
Recql4 |
RecQ like helicase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of RECQL4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity increases localization |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein] Glucosamine results in decreased activity of RELA protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] Glucosamine results in increased localization of RELA protein |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17238806 PMID:17498959 PMID:18036590 PMID:18080321 PMID:18205790 PMID:18340449 PMID:18786831 PMID:19020780 PMID:19375915 PMID:20307528 PMID:20737476 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Relb |
RELB proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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G |
Rhob |
ras homolog family member B |
increases expression |
ISO |
Glucosamine results in increased expression of RHOB mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Rhoc |
ras homolog family member C |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of RHOC mRNA |
CTD |
PMID:16142878 |
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NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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G |
Rnd1 |
Rho family GTPase 1 |
multiple interactions decreases expression |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA] Glucosamine results in decreased expression of RND1 mRNA |
CTD |
PMID:17178593 PMID:18173918 |
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NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:19254699 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6KB1 protein |
CTD |
PMID:19254699 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Runx2 |
RUNX family transcription factor 2 |
increases phosphorylation increases expression multiple interactions |
ISO |
Glucosamine analog results in increased phosphorylation of RUNX2 protein Glucosamine analog results in increased expression of RUNX2 mRNA 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] |
CTD |
PMID:20458730 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of SCD2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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G |
Sdc2 |
syndecan 2 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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G |
Sdc4 |
syndecan 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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G |
Selenbp1 |
selenium binding protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SELENBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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G |
Serpinb2 |
serpin family B member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SERPINB2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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G |
Serpinh1 |
serpin family H member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SERPINH1 protein |
CTD |
PMID:16380481 |
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NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SFRP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SGK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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G |
Shcbp1 |
SHC binding and spindle associated 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SHCBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
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G |
Slc17a1 |
solute carrier family 17 member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC17A1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
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G |
Slc23a2 |
solute carrier family 23 member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SLC23A2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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G |
Slc2a2 |
solute carrier family 2 member 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC2A2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions decreases expression increases uptake |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein] Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein SLC2A4 protein results in increased uptake of Glucosamine Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine] |
CTD |
PMID:19373748 PMID:20165829 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Slc2a6 |
solute carrier family 2 member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SLC2A6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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G |
Slc37a4 |
solute carrier family 37 member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC37A4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
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G |
Slc4a4 |
solute carrier family 4 member 4 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC4A4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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G |
Slc7a8 |
solute carrier family 7 member 8 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of SLC7A8 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr15:28,183,013...28,242,717
Ensembl chr15:28,183,015...28,242,717
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G |
Smad2 |
SMAD family member 2 |
multiple interactions increases phosphorylation |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:20458730 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smpd3 |
sphingomyelin phosphodiesterase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SMPD3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
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G |
Sox4 |
SRY-box transcription factor 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA] Glucosamine results in decreased expression of SOX4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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G |
Srsf3 |
serine and arginine rich splicing factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SRSF3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
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G |
St6gal1 |
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ST6GAL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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G |
Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] |
CTD |
PMID:16431966 PMID:17238806 |
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NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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G |
Tacc3 |
transforming, acidic coiled-coil containing protein 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TACC3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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G |
Testin |
testin gene |
decreases expression |
EXP |
Glucosamine results in decreased expression of TESTIN mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions |
EXP |
[Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] |
CTD |
PMID:1518840 |
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NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression |
EXP |
Glucosamine analog results in increased expression of TGFB1 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
increases expression multiple interactions |
ISO |
Glucosamine analog results in increased expression of TGFBR1 protein 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein] |
CTD |
PMID:20458730 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Thbs4 |
thrombospondin 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of TIMP2 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
multiple interactions increases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA Glucosamine results in increased expression of TIMP3 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA] |
CTD |
PMID:17109745 PMID:17605605 |
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NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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G |
Tinag |
tubulointerstitial nephritis antigen |
increases expression |
ISO |
Glucosamine results in increased expression of TINAG mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
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G |
Tk1 |
thymidine kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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G |
Tlr1 |
toll-like receptor 1 |
increases expression |
ISO |
Glucosamine results in increased expression of TLR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
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G |
Tnf |
tumor necrosis factor |
decreases secretion multiple interactions decreases expression |
ISO EXP |
Glucosamine results in decreased secretion of TNF protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] [Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
CTD |
PMID:14507305 PMID:16431966 PMID:16445576 PMID:16822504 PMID:17238806 PMID:18173918 PMID:18205790 PMID:18786831 PMID:19020780 PMID:19098112 PMID:20093129 PMID:20110869 PMID:20113495 PMID:20737476 PMID:38437956 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip6 |
TNF alpha induced protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
multiple interactions |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein |
CTD |
PMID:17996099 |
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NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions increases expression |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] |
CTD |
PMID:17996099 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Tnk2 |
tyrosine kinase, non-receptor, 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009
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G |
Top2a |
DNA topoisomerase II alpha |
decreases expression |
EXP |
Glucosamine results in decreased expression of TOP2A mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of TRPV4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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G |
Txn1 |
thioredoxin 1 |
decreases expression |
EXP ISO |
Glucosamine results in decreased expression of TXN1 protein |
CTD |
PMID:17178593 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
EXP ISO |
Glucosamine results in increased expression of TXNIP protein Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Ucp2 |
uncoupling protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of UCP2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
increases expression |
ISO |
Glucosamine results in increased expression of UQCRH mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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G |
Vamp1 |
vesicle-associated membrane protein 1 |
increases expression |
EXP |
Glucosamine results in increased expression of VAMP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349
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G |
Vcan |
versican |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression decreases expression |
ISO EXP |
Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein] Glucosamine results in increased expression of VEGFA protein Glucosamine results in decreased expression of VEGFA protein |
CTD |
PMID:16324875 PMID:19254699 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfd |
vascular endothelial growth factor D |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of VEGFD mRNA Glucosamine results in decreased expression of VEGFD mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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G |
Vnn1 |
vanin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of VNN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions increases splicing increases expression decreases splicing |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] Glucosamine results in increased expression of XBP1 protein alternative form 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] Glucosamine results in decreased splicing of XBP1 mRNA |
CTD |
PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] |
CTD |
PMID:11801247 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
Glucosamine results in increased expression of ZFP467 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of CEBPA protein |
CTD |
PMID:19427183 |
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NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of DLK1 mRNA |
CTD |
PMID:19427183 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of FABP4 mRNA |
CTD |
PMID:19427183 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of FAS mRNA |
CTD |
PMID:19427183 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
multiple interactions increases abundance |
ISO |
Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of glucosamine 6-phosphate] |
CTD |
PMID:27469509 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Lep |
leptin |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of LEP mRNA |
CTD |
PMID:19427183 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipe |
lipase E, hormone sensitive type |
increases expression |
ISO |
glucosamine 6-phosphate results in increased expression of LIPE mRNA |
CTD |
PMID:19427183 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Lpl |
lipoprotein lipase |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of LPL mRNA |
CTD |
PMID:19427183 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of PPARG protein |
CTD |
PMID:19427183 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of SREBF1 protein |
CTD |
PMID:19427183 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Tnf |
tumor necrosis factor |
decreases expression |
ISO |
glucosamine 6-phosphate results in decreased expression of TNF mRNA |
CTD |
PMID:19427183 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
decreases cleavage |
ISO |
mannosamine results in decreased cleavage of ADAMTS5 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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G |
Chit1 |
chitinase 1 |
decreases activity |
ISO |
allosamidin results in decreased activity of CHIT1 protein |
CTD |
PMID:16005164 |
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NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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G |
Aacs |
acetoacetyl-CoA synthetase |
increases expression |
ISO |
Glucosamine results in increased expression of AACS mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:31,113,098...31,156,411
Ensembl chr12:31,113,098...31,160,954
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ABCG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
ISO |
Glucosamine results in increased expression of ACACA mRNA |
CTD |
PMID:22096489 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acan |
aggrecan |
multiple interactions increases expression decreases expression affects expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine results in decreased cleavage of and results in decreased secretion of ACAN protein Glucosamine results in increased expression of ACAN mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA] Glucosamine analog results in increased expression of ACAN protein; Glucosamine results in increased expression of ACAN mRNA; Glucosamine results in increased expression of ACAN protein Glucosamine analog results in decreased expression of ACAN mRNA Glucosamine analog affects the expression of ACAN mRNA |
CTD |
PMID:12801482 PMID:16300972 PMID:16872674 PMID:17109745 PMID:17337215 PMID:18321735 PMID:19909832 More...
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NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
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G |
Acot1 |
acyl-CoA thioesterase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ACOT1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acox2 |
acyl-CoA oxidase 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ACOX2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acss2 |
acyl-CoA synthetase short-chain family member 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ACSS2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
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G |
Adam15 |
ADAM metallopeptidase domain 15 |
multiple interactions decreases expression |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adamts1 |
ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
decreases expression multiple interactions |
ISO EXP |
Glucosamine analog results in decreased expression of ADAMTS1 mRNA Glucosamine results in decreased expression of ADAMTS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA] |
CTD |
PMID:16300972 PMID:17109745 |
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NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
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G |
Adamts20 |
ADAM metallopeptidase with thrombospondin type 1 motif, 20 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS20 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 7:125,396,227...125,528,020
Ensembl chr 7:125,397,734...125,527,777
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G |
Adamts4 |
ADAM metallopeptidase with thrombospondin type 1 motif, 4 |
increases expression |
EXP |
Glucosamine results in increased expression of ADAMTS4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:83,670,556...83,680,045
Ensembl chr13:83,670,183...83,680,065
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G |
Adamts5 |
ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
decreases expression multiple interactions |
ISO |
Glucosamine analog results in decreased expression of ADAMTS5 mRNA Glucosamine results in decreased cleavage of and results in decreased activity of ADAMTS5 protein alternative form |
CTD |
PMID:16300972 PMID:19909832 |
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NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205
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G |
Adamts9 |
ADAM metallopeptidase with thrombospondin type 1 motif, 9 |
decreases cleavage |
ISO |
Glucosamine results in decreased cleavage of ADAMTS9 protein alternative form |
CTD |
PMID:19909832 |
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NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
increases expression |
ISO EXP |
Glucosamine results in increased expression of ADIPOQ mRNA |
CTD |
PMID:15694357 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Afp |
alpha-fetoprotein |
increases expression |
ISO |
Glucosamine results in increased expression of AFP mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Agt |
angiotensinogen |
increases expression |
ISO |
Glucosamine results in increased expression of AGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahi1 |
Abelson helper integration site 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of AHI1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:15,762,485...15,891,213
Ensembl chr 1:15,762,462...15,891,041
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G |
Akt1 |
AKT serine/threonine kinase 1 |
affects phosphorylation multiple interactions |
ISO |
Glucosamine analog affects the phosphorylation of AKT1 protein Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]] Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:18080321 PMID:18340449 PMID:30602124 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Alg12 |
ALG12, alpha-1,6-mannosyltransferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of ALG12 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions increases expression increases activity |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased activity of ALPL protein] Glucosamine analog results in increased expression of ALPL mRNA |
CTD |
PMID:20458730 |
|
NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Apoa1 |
apolipoprotein A1 |
increases secretion increases stability |
ISO |
Glucosamine results in increased secretion of APOA1 protein Glucosamine results in increased stability of APOA1 mRNA |
CTD |
PMID:15164326 |
|
NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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|
G |
Apob |
apolipoprotein B |
multiple interactions increases degradation increases ubiquitination decreases secretion decreases localization decreases expression |
ISO EXP |
acetylleucyl-leucyl-norleucinal inhibits the reaction [Glucosamine results in decreased expression of and results in decreased secretion of APOB protein]; Glucosamine results in decreased expression of and results in decreased secretion of APOB protein; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein] Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] Glucosamine results in increased ubiquitination of APOB protein Glucosamine results in decreased localization of APOB protein Glucosamine results in decreased expression of APOB protein |
CTD |
PMID:15618547 PMID:19383982 |
|
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] |
CTD |
PMID:16380481 |
|
NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Ass1 |
argininosuccinate synthase 1 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903
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G |
Atf3 |
activating transcription factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATF3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of ATF4 mRNA; Glucosamine results in increased expression of ATF4 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
|
NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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|
G |
Atf6 |
activating transcription factor 6 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in increased expression of ATF6 protein ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA] Glucosamine results in decreased expression of ATF6 mRNA |
CTD |
PMID:17178593 PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atf7ip |
activating transcription factor 7 interacting protein |
increases expression |
ISO |
Glucosamine results in increased expression of ATF7IP mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:169,385,872...169,471,652
Ensembl chr 4:169,385,872...169,471,650
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ATP2A2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Azin1 |
antizyme inhibitor 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of AZIN1 mRNA IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
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G |
B3gat3 |
beta-1,3-glucuronyltransferase 3 |
multiple interactions increases expression |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA] |
CTD |
PMID:11229466 PMID:11801247 |
|
NCBI chr 1:205,817,374...205,823,928
Ensembl chr 1:205,817,378...205,837,807
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression multiple interactions |
ISO |
Glucosamine results in decreased expression of BCL2L1 protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of BCL2L1 protein] |
CTD |
PMID:15972124 PMID:16850161 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression |
ISO |
Glucosamine results in decreased expression of BDNF mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Bglap |
bone gamma-carboxyglutamate protein |
increases expression |
ISO |
Glucosamine analog results in increased expression of BGLAP mRNA |
CTD |
PMID:20458730 |
|
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bgn |
biglycan |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of BMAL1 mRNA; Glucosamine results in decreased expression of BMAL1 protein |
CTD |
PMID:24442997 |
|
NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Bmp4 |
bone morphogenetic protein 4 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of BMP4 mRNA Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
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G |
Bmp6 |
bone morphogenetic protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA] Glucosamine results in decreased expression of BMP6 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA] Glucosamine results in increased expression of BMP7 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Calr |
calreticulin |
decreases expression |
ISO |
Glucosamine results in decreased expression of CALR mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Car3 |
carbonic anhydrase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CAR3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Casp3 |
caspase 3 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of CASP3 protein Glucosamine results in increased activity of and results in increased cleavage of CASP3 protein |
CTD |
PMID:16850161 PMID:22020377 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of CASP4 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Cbr2 |
carbonyl reductase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr10:106,008,535...106,012,838
Ensembl chr10:105,991,589...106,013,001
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G |
Cbr3 |
carbonyl reductase 3 |
increases expression |
ISO |
Glucosamine results in increased expression of CBR3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr11:33,008,615...33,016,877
Ensembl chr11:33,008,615...33,016,875
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions increases expression |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein] Glucosamine results in increased expression of CCL2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA] |
CTD |
PMID:17109745 PMID:18080321 PMID:18949387 PMID:19020780 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein] Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA] |
CTD |
PMID:17109745 PMID:18080321 |
|
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression |
EXP |
Glucosamine analog results in increased expression of CCN2 mRNA |
CTD |
PMID:21466783 |
|
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnb1 |
cyclin B1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CCNB1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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G |
Cd24 |
CD24 molecule |
increases expression |
ISO |
Glucosamine results in increased expression of CD24A mRNA |
CTD |
PMID:17178593 |
|
NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd28 |
Cd28 molecule |
increases expression |
EXP |
Glucosamine results in increased expression of CD28 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cdc20 |
cell division cycle 20 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC20 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdc23 |
cell division cycle 23 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDC23 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr18:26,236,891...26,260,611
Ensembl chr18:26,236,890...26,291,163
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G |
Cdk1 |
cyclin-dependent kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDK1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
EXP ISO |
Glucosamine results in increased expression of CDKN1A protein Glucosamine results in increased expression of CDKN1A mRNA |
CTD |
PMID:15654767 PMID:17178593 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN1B protein |
CTD |
PMID:15654767 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cdkn3 |
cyclin-dependent kinase inhibitor 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CDKN3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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G |
Cenpf |
centromere protein F |
decreases expression |
EXP |
Glucosamine results in decreased expression of CENPF mRNA |
CTD |
PMID:17109745 |
|
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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G |
Chi3l1 |
chitinase 3 like 1 |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of CHI3L1 mRNA |
CTD |
PMID:16142878 |
|
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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|
G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions decreases activity |
ISO |
Glucosamine analog results in decreased activity of and results in decreased localization of CHUK protein Glucosamine analog results in decreased activity of CHUK protein |
CTD |
PMID:20113495 |
|
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Ckap2 |
cytoskeleton associated protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
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G |
Clock |
clock circadian regulator |
decreases expression |
ISO |
Glucosamine results in decreased expression of CLOCK mRNA; Glucosamine results in decreased expression of CLOCK protein |
CTD |
PMID:24442997 |
|
NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
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G |
Clta |
clathrin, light chain A |
decreases expression |
EXP |
Glucosamine results in decreased expression of CLTA mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
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G |
Col11a1 |
collagen type XI alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:201,820,715...202,013,853
Ensembl chr 2:201,820,715...202,013,853
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions decreases expression |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA] Glucosamine results in decreased expression of COL1A1 mRNA |
CTD |
PMID:18321735 |
|
NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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|
G |
Col2a1 |
collagen type II alpha 1 chain |
multiple interactions affects expression increases expression |
ISO EXP |
Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA] Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA] Glucosamine analog affects the expression of COL2A1 mRNA Glucosamine analog results in increased expression of COL2A1 mRNA; Glucosamine results in increased expression of COL2A1 mRNA |
CTD |
PMID:16300972 PMID:17109745 PMID:17337215 PMID:18321735 |
|
NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546
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|
G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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|
G |
Col8a1 |
collagen type VIII alpha 1 chain |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr11:42,776,851...42,906,432
Ensembl chr11:42,777,628...42,906,424
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|
G |
Csf1 |
colony stimulating factor 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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|
G |
Csf2 |
colony stimulating factor 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA] Glucosamine results in increased expression of CSF2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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|
G |
Csf3 |
colony stimulating factor 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA] Glucosamine results in increased expression of CSF3 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Ctsd |
cathepsin D |
affects localization multiple interactions increases activity decreases expression |
ISO |
Glucosamine affects the localization of CTSD protein pepstatin inhibits the reaction [Glucosamine results in decreased expression of CTSD protein alternative form] Glucosamine results in increased activity of CTSD protein |
CTD |
PMID:15972124 PMID:16850161 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Cul2 |
cullin 2 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA] |
CTD |
PMID:18173918 |
|
NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO EXP |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA] |
CTD |
PMID:17109745 PMID:20737476 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl11 |
C-X-C motif chemokine ligand 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
EXP |
Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cyba |
cytochrome b-245 alpha chain |
decreases expression |
ISO |
Glucosamine results in decreased expression of CYBA mRNA |
CTD |
PMID:18077487 |
|
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
affects localization |
ISO |
Glucosamine affects the localization of CYCS protein |
CTD |
PMID:15972124 PMID:22020377 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp51 |
cytochrome P450, family 51 |
increases expression |
ISO |
Glucosamine results in increased expression of CYP51 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
ISO |
Glucosamine results in increased expression of DBI mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions decreases expression |
ISO |
Glucosamine results in increased expression of DDIT3 mRNA; Glucosamine results in increased expression of DDIT3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of DDIT3 protein] Glucosamine results in decreased expression of DDIT3 mRNA |
CTD |
PMID:16380481 PMID:17178593 PMID:30602124 PMID:33812996 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4l |
DNA-damage-inducible transcript 4-like |
increases expression |
EXP |
Glucosamine results in increased expression of DDIT4L mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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G |
Dhcr7 |
7-dehydrocholesterol reductase |
increases expression |
ISO |
Glucosamine results in increased expression of DHCR7 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
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G |
Dnajb11 |
DnaJ heat shock protein family (Hsp40) member B11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB11 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407
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G |
Dnajb9 |
DnaJ heat shock protein family (Hsp40) member B9 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJB9 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063
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G |
Dnajc3 |
DnaJ heat shock protein family (Hsp40) member C3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of DNAJC3 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181
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G |
Dspp |
dentin sialophosphoprotein |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of DSPP mRNA |
CTD |
PMID:20458730 |
|
NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
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G |
Dusp5 |
dual specificity phosphatase 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA] Glucosamine results in increased expression of DUSP5 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
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G |
Dusp7 |
dual specificity phosphatase 7 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 8:107,009,369...107,016,404
Ensembl chr 8:107,008,528...107,016,404
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of DYNC1I1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EDEM1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases expression increases phosphorylation |
EXP ISO |
EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased expression of EIF2AK3 protein NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein] EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] Glucosamine results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO EXP |
Glucosamine results in increased phosphorylation of EIF2S1 protein NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; EIF2AK3 protein affects the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; GSK2656157 inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:16324875 PMID:19383982 PMID:30602124 PMID:33812996 |
|
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
increases expression |
ISO |
Glucosamine results in increased expression of ELOVL6 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Epas1 |
endothelial PAS domain protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of EPAS1 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228
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G |
Eprs1 |
glutamyl-prolyl-tRNA synthetase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of EPRS1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr13:96,901,548...96,971,966
Ensembl chr13:96,901,575...96,971,966
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression |
ISO |
ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA] |
CTD |
PMID:30602124 PMID:33812996 |
|
NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp4 |
fatty acid binding protein 4 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of FABP4 mRNA |
CTD |
PMID:15694357 |
|
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
Glucosamine results in increased expression of FASN mRNA |
CTD |
PMID:22096489 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fbp2 |
fructose-bisphosphatase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of FBP2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions |
EXP |
Glucosamine promotes the reaction [Glucose results in increased expression of FGF2 mRNA] |
CTD |
PMID:1518840 |
|
NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf7 |
fibroblast growth factor 7 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of FGF7 mRNA IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fgf9 |
fibroblast growth factor 9 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA] Glucosamine results in increased expression of FGF9 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr15:32,208,993...32,254,952
Ensembl chr15:32,210,074...32,253,309
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA] Glucosamine results in increased expression of FGFR1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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|
G |
Fkbp11 |
FKBP prolyl isomerase 11 |
decreases expression |
ISO |
Glucosamine results in decreased expression of FKBP11 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:129,871,870...129,877,760
Ensembl chr 7:129,871,870...129,875,303
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G |
Fn1 |
fibronectin 1 |
decreases expression |
ISO EXP |
Glucosamine results in decreased expression of FN1 protein |
CTD |
PMID:17178593 |
|
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of FOS mRNA] Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS protein] |
CTD |
PMID:19375915 PMID:21825963 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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|
G |
Furin |
furin (paired basic amino acid cleaving enzyme) |
decreases cleavage multiple interactions |
ISO |
Glucosamine results in decreased cleavage of FURIN protein alternative form Glucosamine results in decreased glycosylation of and results in decreased activity of FURIN protein |
CTD |
PMID:19909832 |
|
NCBI chr 1:134,348,142...134,361,182
Ensembl chr 1:134,348,144...134,364,314
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
increases expression |
EXP |
Glucosamine results in increased expression of FXYD2 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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G |
Gatm |
glycine amidinotransferase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GATM mRNA |
CTD |
PMID:17109745 |
|
NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
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G |
Gck |
glucokinase |
decreases expression |
EXP |
Glucosamine results in decreased expression of GCK mRNA |
CTD |
PMID:11893929 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
increases expression |
ISO |
Glucosamine analog results in increased expression of GCLC mRNA |
CTD |
PMID:21825963 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gfpt1 |
glutamine fructose-6-phosphate transaminase 1 |
multiple interactions |
EXP |
[Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein |
CTD |
PMID:9453242 |
|
NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
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G |
Glrx |
glutaredoxin |
increases expression |
ISO |
Glucosamine results in increased expression of GLRX mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
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G |
Gnpnat1 |
glucosamine-phosphate N-acetyltransferase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of GNPNAT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739
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G |
Gnptab |
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta |
increases expression |
ISO |
Glucosamine results in increased expression of GNPTAB mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933
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G |
Gpd1l |
glycerol-3-phosphate dehydrogenase 1 like |
increases expression |
ISO |
Glucosamine results in increased expression of GPD1L mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 8:114,591,103...114,620,771
Ensembl chr 8:114,588,487...114,620,723
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases phosphorylation multiple interactions |
ISO |
Glucosamine results in decreased phosphorylation of GSK3B protein Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gspt1 |
G1 to S phase transition 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA] |
CTD |
PMID:18173918 |
|
NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198
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|
G |
Gstt1 |
glutathione S-transferase theta 1 |
increases expression |
ISO |
Glucosamine results in increased expression of GSTT1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
decreases expression multiple interactions |
EXP |
Glucosamine results in decreased expression of HAPLN1 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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G |
Herpud1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HERPUD1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424
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|
G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions decreases expression |
ISO |
Glucosamine affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of HIF1A protein]; Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] Glucosamine results in decreased expression of HIF1A mRNA; Glucosamine results in decreased expression of HIF1A protein |
CTD |
PMID:19254699 PMID:22020377 |
|
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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|
G |
Hk1 |
hexokinase 1 |
increases expression |
ISO EXP |
Glucosamine results in increased expression of HK1 mRNA |
CTD |
PMID:11893929 PMID:17178593 |
|
NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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|
G |
Hmga1 |
high mobility group AT-hook 1 |
increases expression |
EXP |
Glucosamine results in increased expression of HMGA1 mRNA |
CTD |
PMID:17109745 |
|
NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
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|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of HMGCS1 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
|
|
G |
Hmmr |
hyaluronan-mediated motility receptor |
decreases expression |
EXP |
Glucosamine results in decreased expression of HMMR mRNA |
CTD |
PMID:17109745 |
|
NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
|
|
G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein] Glucosamine results in increased expression of HMOX1 mRNA; Glucosamine results in increased expression of HMOX1 protein |
CTD |
PMID:18077487 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hoxa1 |
homeobox A1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HOXA1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:81,255,814...81,258,587
Ensembl chr 4:81,255,883...81,258,504
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G |
Hpgd |
15-hydroxyprostaglandin dehydrogenase |
decreases expression |
EXP |
Glucosamine results in decreased expression of HPGD mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
decreases expression increases expression |
ISO EXP |
Glucosamine results in decreased expression of HSP90B1 mRNA Glucosamine results in increased expression of HSP90B1 protein |
CTD |
PMID:15618547 PMID:17109745 PMID:17178593 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions increases expression decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein] Glucosamine results in increased expression of HSPA5 mRNA; Glucosamine results in increased expression of HSPA5 protein 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA] Glucosamine results in decreased expression of HSPA5 mRNA |
CTD |
PMID:15618547 PMID:16380481 PMID:17178593 PMID:19383982 PMID:20165829 PMID:22020377 PMID:30602124 PMID:33812996 More...
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hyou1 |
hypoxia up-regulated 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of HYOU1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,706,073...44,718,189
Ensembl chr 8:44,706,263...44,718,186
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions decreases activity |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [Cathelicidins results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] Glucosamine results in decreased activity of ICAM1 protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 PMID:16822504 PMID:17238806 PMID:18949387 PMID:19020780 PMID:19098112 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id1 |
inhibitor of DNA binding 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ID1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Id2 |
inhibitor of DNA binding 2 |
increases expression |
ISO |
Glucosamine results in increased expression of ID2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Id3 |
inhibitor of DNA binding 3 |
increases expression |
ISO |
Glucosamine results in increased expression of ID3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
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G |
Idh1 |
isocitrate dehydrogenase (NADP(+)) 1 |
increases expression |
ISO |
Glucosamine results in increased expression of IDH1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
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G |
Ifit3 |
interferon-induced protein with tetratricopeptide repeats 3 |
increases expression |
ISO |
Glucosamine results in increased expression of IFIT3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
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G |
Ifng |
interferon gamma |
decreases secretion multiple interactions |
ISO |
Glucosamine results in decreased secretion of IFNG protein Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IFNG results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]] |
CTD |
PMID:14507305 PMID:16431966 PMID:16822504 PMID:17238806 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA] Glucosamine results in decreased expression of IGFBP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp4 |
insulin-like growth factor binding protein 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of IGFBP4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225
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G |
Igfbp5 |
insulin-like growth factor binding protein 5 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA] Glucosamine results in increased expression of IGFBP5 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] |
CTD |
PMID:18786831 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Ikbkg |
inhibitor of nuclear factor kappa B kinase regulatory subunit gamma |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:152,216,485...152,241,476
Ensembl chr X:152,216,596...152,239,499
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G |
Il11 |
interleukin 11 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA] Glucosamine results in decreased expression of IL13RA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681 Ensembl chr11:115,348,860...115,408,681
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; [Glucosamine co-treated with Chondroitin Sulfates] inhibits the reaction [IL1B protein results in increased secretion of Nitrites]; Glucosamine analog affects the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine analog affects the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine analog affects the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine analog affects the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine analog inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL2 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CCL5 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein]; Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of COL1A1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HMOX1 protein]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B results in increased abundance of Nitrites]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL8 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased secretion of CXCL8 protein]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine promotes the reaction [IL1B results in increased expression of PPARG]; Glucosamine promotes the reaction [IL1B results in increased phosphorylation of AKT1 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] Glucosamine results in increased expression of IL1B mRNA Glucosamine results in decreased expression of IL1B mRNA [IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA; Glucosamine affects the reaction [IL1B results in decreased expression of ADAM15 mRNA]; Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA]; Glucosamine inhibits the reaction [IL1B protein results in decreased activity of B3GAT3 protein]; Glucosamine inhibits the reaction [IL1B protein results in decreased expression of B3GAT3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Glucosamine inhibits the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of ACAN mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL11A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL2A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of COL3A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of FGFR1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of HAPLN1 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAM17 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ADAMTS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of ASS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BGN mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of BMP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL20 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL22 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CCL7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of COL8A1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CSF3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of CXCL5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of DUSP7 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of FGF9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of GREM1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IGFBP5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IKBKG mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL11 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL13RA1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL1B mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of BMP4 mRNA]; Glucosamine promotes the reaction [IL1B results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of ADAM15 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of BGN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of COL11A1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of CXCL12 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of DUSP7 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of IKBKG mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of ADAM17 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of IL1A mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of ADAMTS1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of COL8A1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CSF1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of CXCL1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of FGF7 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of GREM1 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in increased expression of IGFBP3 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of HAPLN1 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of AZIN1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL20 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CCL7 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of CXCL3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
CTD |
PMID:11229466 PMID:11801247 PMID:12681956 PMID:15144122 PMID:16822504 PMID:17109745 PMID:17238806 PMID:17337215 PMID:17605605 PMID:17925024 PMID:18026701 PMID:18077487 PMID:18080321 PMID:18321735 PMID:18340449 PMID:18786831 PMID:19626664 PMID:19656660 PMID:20737476 PMID:21219853 PMID:22089456 PMID:38437956 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1r2 |
interleukin 1 receptor type 2 |
multiple interactions |
EXP |
[IL1B protein co-treated with Glucosamine] results in increased expression of IL1R2 mRNA |
CTD |
PMID:11801247 |
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NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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G |
Il2 |
interleukin 2 |
decreases secretion |
ISO |
Glucosamine results in decreased secretion of IL2 protein |
CTD |
PMID:14507305 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il23r |
interleukin 23 receptor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of IL23R mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
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G |
Il33 |
interleukin 33 |
decreases expression |
EXP |
Glucosamine results in decreased expression of IL33 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL4 protein Glucosamine results in decreased expression of IL4 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il5 |
interleukin 5 |
decreases secretion decreases expression |
ISO |
Glucosamine results in decreased secretion of IL5 protein Glucosamine results in decreased expression of IL5 |
CTD |
PMID:14507305 PMID:21284687 |
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NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
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G |
Il6 |
interleukin 6 |
multiple interactions decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IL6 results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] Glucosamine inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] Glucosamine analog results in decreased expression of IL6 mRNA; Glucosamine results in decreased expression of IL6 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL6 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
CTD |
PMID:16822504 PMID:17109745 PMID:18786831 PMID:19098112 PMID:20093129 PMID:20113495 PMID:20307528 PMID:20737476 PMID:38437956 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Inpp5k |
inositol polyphosphate-5-phosphatase K |
multiple interactions increases expression |
ISO |
NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA] |
CTD |
PMID:33812996 |
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NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]]; [Glucosamine co-treated with INS1 protein] affects the localization of GFPT1 protein; Glucosamine inhibits the reaction [Glucose results in increased secretion of INS1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of Deoxyglucose]; Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS1 results in increased uptake of Deoxyglucose]] [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:9453242 PMID:11893929 PMID:16380481 PMID:20165829 PMID:30602124 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
4-phenylbutyric acid inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]]; Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]; Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]; NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]]; ursodoxicoltaurine inhibits the reaction [Glucosamine inhibits the reaction [INS results in increased uptake of Deoxyglucose]] |
CTD |
PMID:20165829 PMID:33812996 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 mRNA] |
CTD |
PMID:20737476 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Isyna1 |
inositol-3-phosphate synthase 1 |
increases expression |
EXP |
Glucosamine results in increased expression of ISYNA1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression |
EXP ISO |
Glucosamine inhibits the reaction [IL1B results in increased expression of JAK2 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of JAK2 mRNA] [Glucosamine co-treated with Lipopolysaccharides] results in increased phosphorylation of JAK2 protein |
CTD |
PMID:17109745 PMID:38437956 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUN protein] Glucosamine analog inhibits the reaction [Buthionine Sulfoximine results in increased expression of JUN mRNA] |
CTD |
PMID:17925024 PMID:21825963 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Junb |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of JUNB mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of JUNB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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G |
Jund |
JunD proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B protein results in increased activity of JUND protein] |
CTD |
PMID:17925024 |
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NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799
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G |
Kcnj16 |
potassium inwardly-rectifying channel, subfamily J, member 16 |
increases expression |
ISO |
Glucosamine results in increased expression of KCNJ16 mRNA |
CTD |
PMID:17178593 |
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NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702
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G |
Kif11 |
kinesin family member 11 |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF11 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
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G |
Kif4a |
kinesin family member 4A |
decreases expression |
EXP |
Glucosamine results in decreased expression of KIF4A mRNA |
CTD |
PMID:17109745 |
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NCBI chr X:65,721,746...65,824,277
Ensembl chr X:65,721,779...65,824,139
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G |
Klf10 |
KLF transcription factor 10 |
increases expression |
ISO |
Glucosamine results in increased expression of KLF10 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
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G |
Lama4 |
laminin subunit alpha 4 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of LAMA4 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of LAMA4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr20:42,392,268...42,533,347
Ensembl chr20:42,392,268...42,533,347
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Lamc1 |
laminin subunit gamma 1 |
multiple interactions |
ISO |
TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
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G |
Lcn2 |
lipocalin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of LCN2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lepr |
leptin receptor |
multiple interactions affects response to substance |
EXP |
[LEPR protein affects the susceptibility to Glucosamine] which affects the expression of ALB protein |
CTD |
PMID:33345901 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lpin1 |
lipin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of LPIN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Ly6a |
lymphocyte antigen 6 family member A |
increases expression |
ISO |
Glucosamine results in increased expression of LY6A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:107,177,191...107,189,436
Ensembl chr 7:107,183,469...107,189,981
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G |
Mafb |
MAF bZIP transcription factor B |
increases expression |
EXP |
Glucosamine results in increased expression of MAFB mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK1 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK1 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] Glucosamine analog results in increased phosphorylation of MAPK1 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk14 |
mitogen activated protein kinase 14 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:19626664 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MAPK3 protein]; Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK3 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] Glucosamine analog results in increased phosphorylation of MAPK3 protein |
CTD |
PMID:18080321 PMID:18340449 PMID:19375915 PMID:19626664 PMID:20307528 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Glucosamine analog promotes the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [IL1B results in increased phosphorylation of MAPK8 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein] Glucosamine analog results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:18080321 PMID:19626664 PMID:20307528 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression |
ISO |
Glucosamine results in decreased expression of MCL1 mRNA; Glucosamine results in decreased expression of MCL1 protein |
CTD |
PMID:22020377 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mef2a |
myocyte enhancer factor 2a |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of MEF2A protein] Glucosamine results in decreased expression of MEF2A mRNA; Glucosamine results in decreased expression of MEF2A protein |
CTD |
PMID:20165829 |
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NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948
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G |
Mettl1 |
methyltransferase 1, tRNA methylguanosine |
decreases expression |
ISO |
Glucosamine results in decreased expression of METTL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202
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G |
Mfap3l |
microfibril associated protein 3 like |
increases expression |
ISO |
Glucosamine results in increased expression of MFAP3L mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:29,411,643...29,454,665
Ensembl chr16:29,415,849...29,430,863
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G |
Mki67 |
marker of proliferation Ki-67 |
decreases expression |
EXP |
Glucosamine results in decreased expression of MKI67 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP1]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP1 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] |
CTD |
PMID:15144122 PMID:17925024 PMID:18080321 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp10 |
matrix metallopeptidase 10 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of MMP10 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP10 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP10 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
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G |
Mmp12 |
matrix metallopeptidase 12 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of MMP12 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP12 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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G |
Mmp13 |
matrix metallopeptidase 13 |
affects expression multiple interactions increases expression |
ISO EXP |
Glucosamine analog affects the expression of MMP13 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP13 mRNA] Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP13]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP13 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP13 mRNA]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP13 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein] |
CTD |
PMID:15144122 PMID:17109745 PMID:17337215 PMID:17925024 PMID:18080321 PMID:19656660 More...
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP2 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP2 protein] IL1B promotes the reaction [Glucosamine results in increased expression of MMP2 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp3 |
matrix metallopeptidase 3 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of MMP3 mRNA; [Glucosamine co-treated with Chondroitin Sulfates] results in decreased secretion of MMP3 protein; Glucosamine analog inhibits the reaction [IL1B protein results in increased expression of MMP3]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of and results in increased secretion of MMP3 protein]; Glucosamine analog inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 protein]; Glucosamine results in decreased expression of and results in decreased activity of MMP3 protein Glucosamine results in increased expression of MMP3 mRNA Glucosamine inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; Glucosamine inhibits the reaction [IL1B results in increased expression of MMP3 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of MMP3 mRNA] Glucosamine analog results in decreased expression of MMP3 mRNA |
CTD |
PMID:11229466 PMID:12801482 PMID:15144122 PMID:16300972 PMID:17109745 PMID:17925024 PMID:18080321 PMID:18340449 PMID:20110869 More...
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 mRNA]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MMP9 protein] Glucosamine results in increased expression of MMP9 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of MMP9 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of MMP9 mRNA] |
CTD |
PMID:17109745 PMID:17498959 PMID:19375915 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mnda |
myeloid cell nuclear differentiation antigen |
increases expression |
ISO |
Glucosamine results in increased expression of IFI204 mRNA |
CTD |
PMID:17178593 |
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NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201
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G |
Mpo |
myeloperoxidase |
decreases activity |
EXP |
Glucosamine results in decreased activity of MPO protein |
CTD |
PMID:19098112 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mvd |
mevalonate diphosphate decarboxylase |
increases expression |
ISO |
Glucosamine results in increased expression of MVD mRNA |
CTD |
PMID:17178593 |
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NCBI chr19:50,496,366...50,506,429
Ensembl chr19:50,496,367...50,507,971
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G |
Ndufa4 |
Ndufa4, mitochondrial complex associated |
increases expression |
EXP |
Glucosamine results in increased expression of NDUFA4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:40,002,216...40,009,384
Ensembl chr 4:40,002,216...40,023,920
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G |
Nedd4 |
NEDD4 E3 ubiquitin protein ligase |
decreases expression |
EXP |
Glucosamine results in decreased expression of NEDD4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions decreases activity |
ISO EXP |
Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of NFKB1 protein]; Glucosamine inhibits the reaction [IL1B results in increased degradation of NFKB1 protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKB1 protein] Glucosamine results in decreased activity of NFKB1 protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein] |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17498959 PMID:18036590 PMID:18205790 PMID:20737476 More...
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases phosphorylation decreases expression |
ISO EXP |
Glucosamine analog inhibits the reaction [IL1B results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased degradation of NFKBIA protein] Glucosamine results in decreased phosphorylation of NFKBIA protein Glucosamine results in decreased expression of NFKBIA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]; IL1B inhibits the reaction [Glucosamine results in decreased expression of NFKBIA mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA protein modified form]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:12681956 PMID:17109745 PMID:18080321 PMID:18205790 PMID:19098112 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NFKBIB mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of NFKBIB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Ngef |
neuronal guanine nucleotide exchange factor |
increases expression |
ISO |
Glucosamine results in increased expression of NGEF mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of NGF mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression decreases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of NOS2 protein; Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] Glucosamine results in increased expression of NOS2 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of NOS2 mRNA] Glucosamine results in decreased expression of NOS2 mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:17109745 PMID:17440993 PMID:17605605 PMID:18077487 PMID:18205790 PMID:19098112 PMID:20737476 PMID:38437956 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Glucosamine affects the expression of NR1H4 |
CTD |
PMID:19373748 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nsdhl |
NAD(P) dependent steroid dehydrogenase-like |
increases expression |
ISO |
Glucosamine results in increased expression of NSDHL mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142
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G |
Nucb2 |
nucleobindin 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of NUCB2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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G |
Nuf2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
EXP |
Glucosamine results in decreased expression of NUF2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of DDIT3 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of ERN1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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G |
Oat |
ornithine aminotransferase |
multiple interactions |
EXP |
Glucosamine affects the reaction [IL1B results in decreased expression of OAT mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ogt |
O-linked N-acetylglucosamine (GlcNAc) transferase |
decreases expression |
ISO |
Glucosamine results in decreased expression of OGT mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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G |
Orc2 |
origin recognition complex, subunit 2 |
decreases expression |
ISO |
Glucosamine results in decreased expression of ORC2 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195
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G |
Osm |
oncostatin M |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in decreased methylation of IL1B promoter]; Glucosamine inhibits the reaction [[OSM protein co-treated with IL1B protein] results in increased expression of IL1B mRNA] |
CTD |
PMID:21219853 |
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NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
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G |
Ostn |
osteocrin |
increases expression multiple interactions |
ISO |
Glucosamine results in increased expression of OSTN mRNA 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; [INS1 protein co-treated with Glucosamine] results in increased expression of OSTN mRNA; ATF6 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased expression of OSTN mRNA]; GSK2656157 inhibits the reaction [Glucosamine results in increased expression of OSTN mRNA]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]]; OSTN protein affects the reaction [Glucosamine inhibits the reaction [INS1 protein results in increased uptake of 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose]] |
CTD |
PMID:30602124 |
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NCBI chr11:73,442,167...73,478,498
Ensembl chr11:73,442,487...73,468,603
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G |
Oxr1 |
oxidation resistance 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of OXR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:72,528,750...72,965,666
Ensembl chr 7:72,528,786...72,965,666
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G |
Pank1 |
pantothenate kinase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of PANK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:232,324,718...232,395,445
Ensembl chr 1:232,328,430...232,396,829
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions |
ISO |
Glucosamine results in increased cleavage of PARP1 protein pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] |
CTD |
PMID:16850161 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PDGFA mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PDGFA mRNA]; IL1B affects the reaction [Glucosamine affects the expression of PDGFA mRNA] |
CTD |
PMID:17109745 |
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NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdia4 |
protein disulfide isomerase family A, member 4 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
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G |
Pdia6 |
protein disulfide isomerase family A, member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PDIA6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of PDK4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pfkp |
phosphofructokinase, platelet |
increases expression |
ISO |
Glucosamine results in increased expression of PFKP mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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G |
Piga |
phosphatidylinositol glycan anchor biosynthesis, class A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PIGA mRNA |
CTD |
PMID:17178593 |
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NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804
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G |
Pla2g2a |
phospholipase A2 group IIA |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G2A mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G2A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
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G |
Pla2g4a |
phospholipase A2 group 4A |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of PLA2G4A mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G4A mRNA] |
CTD |
PMID:17109745 |
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NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Pla2g5 |
phospholipase A2, group V |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of PLA2G5 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of PLA2G5 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658
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G |
Plat |
plasminogen activator, tissue type |
increases expression |
ISO |
Glucosamine results in increased expression of PLAT mRNA |
CTD |
PMID:17178593 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plk1 |
polo-like kinase 1 |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of PLK1 mRNA Glucosamine results in decreased expression of PLK1 mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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G |
Plpp3 |
phospholipid phosphatase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PLPP3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO EXP |
Glucosamine promotes the reaction [IL1B results in increased expression of PPARG] Glucosamine results in increased expression of PPARG mRNA |
CTD |
PMID:15694357 PMID:22089456 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions decreases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of PPARGC1A protein] Glucosamine results in decreased expression of PPARGC1A mRNA; Glucosamine results in decreased expression of PPARGC1A protein |
CTD |
PMID:20165829 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppm1a |
protein phosphatase, Mg2+/Mn2+ dependent, 1A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPM1A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697
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G |
Ppp1r15a |
protein phosphatase 1, regulatory subunit 15A |
decreases expression |
ISO |
Glucosamine results in decreased expression of PPP1R15A mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
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G |
Prc1 |
protein regulator of cytokinesis 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of PRC1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
PRKAA1 protein promotes the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]; PRKAA1 protein promotes the reaction [NUS1 protein inhibits the reaction [Glucosamine inhibits the reaction [INS protein results in increased phosphorylation of GSK3B protein]]] |
CTD |
PMID:33812996 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Psme3 |
proteasome activator subunit 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of PSME3 |
CTD |
PMID:21697645 |
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NCBI chr10:86,257,672...86,265,458
Ensembl chr10:86,257,668...86,333,804
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G |
Ptges |
prostaglandin E synthase |
multiple interactions |
ISO |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGES protein; Glucosamine inhibits the reaction [IL1B results in increased expression of PTGES mRNA] |
CTD |
PMID:17605605 PMID:22089456 |
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NCBI chr 3:14,177,892...14,189,236
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
increases expression decreases expression multiple interactions decreases glycosylation |
ISO EXP |
Glucosamine analog results in increased expression of PTGS2 protein alternative form Glucosamine results in decreased expression of PTGS2 mRNA Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Glucosamine inhibits the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased secretion of Dinoprostone]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] Glucosamine results in decreased glycosylation of PTGS2 protein [Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in decreased expression of PTGS2 protein; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]; Glucosamine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
CTD |
PMID:12681956 PMID:17440993 PMID:17605605 PMID:18205790 PMID:19656660 PMID:20737476 PMID:22089456 PMID:38437956 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Pttg1 |
PTTG1 regulator of sister chromatid separation, securin |
decreases expression |
EXP |
Glucosamine results in decreased expression of PTTG1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
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G |
Rab32 |
RAB32, member RAS oncogene family |
increases expression |
ISO |
Glucosamine results in increased expression of RAB32 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:4,946,193...4,961,003
Ensembl chr 1:4,945,036...4,960,934
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G |
Racgap1 |
Rac GTPase-activating protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of RACGAP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
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G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
ISO |
Glucosamine results in decreased expression of RBM39 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
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G |
Recql4 |
RecQ like helicase 4 |
increases expression |
ISO |
Glucosamine results in increased expression of RECQL4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 7:108,423,453...108,430,790
Ensembl chr 7:108,423,455...108,430,619
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity increases localization |
ISO EXP |
Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine analog inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B protein results in increased localization of RELA protein]; Glucosamine inhibits the reaction [IL1B results in increased localization of RELA protein]; Glucosamine inhibits the reaction [NFKB1 results in increased degradation of RELA protein]; Glucosamine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein] Glucosamine results in decreased activity of RELA protein Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]; Glucosamine inhibits the reaction [Lipopolysaccharides promotes the reaction [RELA protein binds to NOS2 promoter]]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of RELA mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein] Glucosamine results in increased localization of RELA protein |
CTD |
PMID:12681956 PMID:16431966 PMID:16822504 PMID:17238806 PMID:17498959 PMID:18036590 PMID:18080321 PMID:18205790 PMID:18340449 PMID:18786831 PMID:19020780 PMID:19375915 PMID:20307528 PMID:20737476 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Relb |
RELB proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of RELB mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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G |
Rhob |
ras homolog family member B |
increases expression |
ISO |
Glucosamine results in increased expression of RHOB mRNA |
CTD |
PMID:17178593 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Rhoc |
ras homolog family member C |
decreases expression |
ISO |
Glucosamine analog results in decreased expression of RHOC mRNA |
CTD |
PMID:16142878 |
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NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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G |
Rnd1 |
Rho family GTPase 1 |
multiple interactions decreases expression |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA] Glucosamine results in decreased expression of RND1 mRNA |
CTD |
PMID:17178593 PMID:18173918 |
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NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399
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G |
Rps6 |
ribosomal protein S6 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:19254699 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation |
ISO |
Glucosamine results in decreased phosphorylation of RPS6KB1 protein |
CTD |
PMID:19254699 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Runx2 |
RUNX family transcription factor 2 |
increases phosphorylation increases expression multiple interactions |
ISO |
Glucosamine analog results in increased phosphorylation of RUNX2 protein Glucosamine analog results in increased expression of RUNX2 mRNA 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of RUNX2 protein] |
CTD |
PMID:20458730 |
|
NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Scd2 |
stearoyl-Coenzyme A desaturase 2 |
increases expression |
ISO |
Glucosamine results in increased expression of SCD2 mRNA |
CTD |
PMID:17178593 |
|
NCBI chr 1:243,169,171...243,182,231
Ensembl chr 1:243,169,236...243,182,232
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G |
Sdc2 |
syndecan 2 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SDC2 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of SDC2 mRNA] |
CTD |
PMID:17109745 |
|
NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
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G |
Sdc4 |
syndecan 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of SDC4 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SDC4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
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G |
Selenbp1 |
selenium binding protein 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SELENBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
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Serpinb2 |
serpin family B member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SERPINB2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
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Serpinh1 |
serpin family H member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SERPINH1 protein |
CTD |
PMID:16380481 |
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NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SFRP2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Sgk1 |
serum/glucocorticoid regulated kinase 1 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SGK1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Shcbp1 |
SHC binding and spindle associated 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SHCBP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
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Slc17a1 |
solute carrier family 17 member 1 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC17A1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr17:41,219,461...41,255,199
Ensembl chr17:41,222,049...41,253,304
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Slc23a2 |
solute carrier family 23 member 2 |
increases expression |
EXP |
Glucosamine results in increased expression of SLC23A2 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 3:119,302,651...119,395,289
Ensembl chr 3:119,302,666...119,460,343
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Slc2a2 |
solute carrier family 2 member 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC2A2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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Slc2a4 |
solute carrier family 2 member 4 |
multiple interactions decreases expression increases uptake |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ATF6 mutant form inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in decreased expression of SLC2A4 protein] Glucosamine results in decreased expression of SLC2A4 mRNA; Glucosamine results in decreased expression of SLC2A4 protein SLC2A4 protein results in increased uptake of Glucosamine Glucosamine inhibits the reaction [SLC2A4 protein results in increased uptake of Glucose]; Glucose inhibits the reaction [SLC2A4 protein results in increased uptake of Glucosamine] |
CTD |
PMID:19373748 PMID:20165829 |
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc2a6 |
solute carrier family 2 member 6 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SLC2A6 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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Slc37a4 |
solute carrier family 37 member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of SLC37A4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301
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Slc4a4 |
solute carrier family 4 member 4 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SLC4A4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
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Slc7a8 |
solute carrier family 7 member 8 |
increases expression multiple interactions |
EXP |
Glucosamine results in increased expression of SLC7A8 mRNA Glucosamine inhibits the reaction [IL1B results in increased expression of SLC7A8 mRNA]; IL1B inhibits the reaction [Glucosamine results in decreased expression of SLC7A8 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr15:28,183,013...28,242,717
Ensembl chr15:28,183,015...28,242,717
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Smad2 |
SMAD family member 2 |
multiple interactions increases phosphorylation |
ISO |
4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased phosphorylation of SMAD2 protein] |
CTD |
PMID:20458730 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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Smpd3 |
sphingomyelin phosphodiesterase 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of SMPD3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749
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G |
Sox4 |
SRY-box transcription factor 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of SOX4 mRNA] Glucosamine results in decreased expression of SOX4 mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665
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G |
Srsf3 |
serine and arginine rich splicing factor 3 |
decreases expression |
ISO |
Glucosamine results in decreased expression of SRSF3 mRNA |
CTD |
PMID:17178593 |
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NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
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G |
St6gal1 |
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
increases expression |
ISO |
Glucosamine results in increased expression of ST6GAL1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
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Stat1 |
signal transducer and activator of transcription 1 |
multiple interactions |
ISO |
Glucosamine inhibits the reaction [IFNG results in increased localization of STAT1 protein modified form]; Glucosamine inhibits the reaction [IFNG results in increased phosphorylation of and results in increased localization of STAT1 protein] |
CTD |
PMID:16431966 PMID:17238806 |
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NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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G |
Tacc3 |
transforming, acidic coiled-coil containing protein 3 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TACC3 mRNA |
CTD |
PMID:17109745 |
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NCBI chr14:77,051,209...77,065,343
Ensembl chr14:77,051,215...77,065,219
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G |
Testin |
testin gene |
decreases expression |
EXP |
Glucosamine results in decreased expression of TESTIN mRNA |
CTD |
PMID:17109745 |
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NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
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G |
Tgfa |
transforming growth factor alpha |
multiple interactions |
EXP |
[Glucose co-treated with Glucosamine] results in increased expression of TGFA protein; Glucosamine promotes the reaction [Glucose results in increased expression of TGFA mRNA] |
CTD |
PMID:1518840 |
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NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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Tgfb1 |
transforming growth factor, beta 1 |
increases expression |
EXP |
Glucosamine analog results in increased expression of TGFB1 mRNA |
CTD |
PMID:21466783 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgfbr1 |
transforming growth factor, beta receptor 1 |
increases expression multiple interactions |
ISO |
Glucosamine analog results in increased expression of TGFBR1 protein 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Glucosamine analog results in increased expression of TGFBR1 protein] |
CTD |
PMID:20458730 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Thbs4 |
thrombospondin 4 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in decreased expression of THBS4 mRNA]; IL1B promotes the reaction [Glucosamine results in decreased expression of THBS4 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TIMP1 mRNA]; IL1B promotes the reaction [Glucosamine results in increased expression of TIMP1 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Timp2 |
TIMP metallopeptidase inhibitor 2 |
affects expression multiple interactions |
EXP |
Glucosamine affects the expression of TIMP2 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Timp3 |
TIMP metallopeptidase inhibitor 3 |
multiple interactions increases expression |
ISO EXP |
[Glucosamine co-treated with Chondroitin Sulfates co-treated with IL1B protein] results in increased expression of TIMP3 mRNA Glucosamine results in increased expression of TIMP3 mRNA Glucosamine inhibits the reaction [IL1B results in decreased expression of TIMP3 mRNA]; IL1B affects the reaction [Glucosamine results in increased expression of TIMP3 mRNA] |
CTD |
PMID:17109745 PMID:17605605 |
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NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839
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Tinag |
tubulointerstitial nephritis antigen |
increases expression |
ISO |
Glucosamine results in increased expression of TINAG mRNA |
CTD |
PMID:17178593 |
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NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
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G |
Tk1 |
thymidine kinase 1 |
decreases expression |
EXP |
Glucosamine results in decreased expression of TK1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
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Tlr1 |
toll-like receptor 1 |
increases expression |
ISO |
Glucosamine results in increased expression of TLR1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
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Tnf |
tumor necrosis factor |
decreases secretion multiple interactions decreases expression |
ISO EXP |
Glucosamine results in decreased secretion of TNF protein Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] Glucosamine analog results in decreased expression of TNF mRNA; Glucosamine results in decreased expression of TNF mRNA Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]; Glucosamine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Glucosamine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] [Glucosamine co-treated with Chondroitin Sulfates] results in decreased expression of TNF; Alloxan inhibits the reaction [Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [[IL6 co-treated with TNF] results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [IFNG promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [IL1B promotes the reaction [TNF results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IFNG results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF promotes the reaction [IL1B results in increased expression of ICAM1 protein]]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CCL2 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of CUL2 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of GSPT1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein]; Glucosamine inhibits the reaction [TNF results in increased expression of IL6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of RND1 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased localization of RELA protein]; Glucosamine inhibits the reaction [TNF results in increased phosphorylation of RELA protein]; Glucosamine promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
CTD |
PMID:14507305 PMID:16431966 PMID:16445576 PMID:16822504 PMID:17238806 PMID:18173918 PMID:18205790 PMID:18786831 PMID:19020780 PMID:19098112 PMID:20093129 PMID:20110869 PMID:20113495 PMID:20737476 PMID:38437956 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip6 |
TNF alpha induced protein 6 |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNFAIP6 mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of TNFAIP6 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfrsf11b |
TNF receptor superfamily member 11B |
multiple interactions |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine co-treated with Cholecalciferol] results in increased expression of TNFRSF11B protein; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B mRNA; [Chondroitin Sulfates co-treated with Glucosamine] results in increased expression of TNFRSF11B protein |
CTD |
PMID:17996099 |
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NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnfrsf1a |
TNF receptor superfamily member 1A |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1A mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Tnfsf11 |
TNF superfamily member 11 |
multiple interactions increases expression |
ISO |
[Chondroitin Sulfates co-treated with Glucosamine] inhibits the reaction [Cholecalciferol results in increased expression of TNFSF11 mRNA]; Chondroitin Sulfates inhibits the reaction [Glucosamine results in increased expression of TNFSF11 mRNA] |
CTD |
PMID:17996099 |
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NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445
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G |
Tnk2 |
tyrosine kinase, non-receptor, 2 |
multiple interactions |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of TNK2 mRNA] |
CTD |
PMID:17109745 |
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NCBI chr11:68,114,725...68,154,254
Ensembl chr11:68,114,726...68,154,009
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G |
Top2a |
DNA topoisomerase II alpha |
decreases expression |
EXP |
Glucosamine results in decreased expression of TOP2A mRNA |
CTD |
PMID:17109745 |
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NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
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Traf6 |
TNF receptor associated factor 6 |
multiple interactions |
ISO |
Glucosamine analog inhibits the reaction [TNF results in increased expression of TRAF6 mRNA]; Glucosamine inhibits the reaction [TNF results in increased expression of TRAF6 mRNA] |
CTD |
PMID:18173918 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases expression |
ISO |
Glucosamine results in increased expression of TRPV4 mRNA |
CTD |
PMID:17178593 |
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NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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Txn1 |
thioredoxin 1 |
decreases expression |
EXP ISO |
Glucosamine results in decreased expression of TXN1 protein |
CTD |
PMID:17178593 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
EXP ISO |
Glucosamine results in increased expression of TXNIP protein Glucosamine results in increased expression of TXNIP mRNA; Glucosamine results in increased expression of TXNIP protein Glucosamine promotes the reaction [TXNIP results in increased abundance of Reactive Oxygen Species]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMB1 mRNA]; TXNIP promotes the reaction [Glucosamine results in increased expression of LAMC1 mRNA] |
CTD |
PMID:17178593 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Ucp2 |
uncoupling protein 2 |
decreases expression |
EXP |
Glucosamine results in decreased expression of UCP2 mRNA |
CTD |
PMID:11893929 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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Uqcrh |
ubiquinol-cytochrome c reductase hinge protein |
increases expression |
ISO |
Glucosamine results in increased expression of UQCRH mRNA |
CTD |
PMID:17178593 |
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NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
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Vamp1 |
vesicle-associated membrane protein 1 |
increases expression |
EXP |
Glucosamine results in increased expression of VAMP1 mRNA |
CTD |
PMID:17109745 |
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NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349
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Vcan |
versican |
multiple interactions decreases expression |
EXP |
Glucosamine inhibits the reaction [IL1B results in increased expression of VCAN mRNA]; IL1B affects the reaction [Glucosamine results in decreased expression of VCAN mRNA] |
CTD |
PMID:17109745 |
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NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions increases expression decreases expression |
ISO EXP |
Glucosamine inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA protein] Glucosamine results in increased expression of VEGFA protein Glucosamine results in decreased expression of VEGFA protein |
CTD |
PMID:16324875 PMID:19254699 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfd |
vascular endothelial growth factor D |
increases expression decreases expression |
ISO EXP |
Glucosamine results in increased expression of VEGFD mRNA Glucosamine results in decreased expression of VEGFD mRNA |
CTD |
PMID:17109745 PMID:17178593 |
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NCBI chr X:30,073,122...30,108,413
Ensembl chr X:30,074,163...30,108,295
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Vnn1 |
vanin 1 |
increases expression |
ISO |
Glucosamine results in increased expression of VNN1 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions increases splicing increases expression decreases splicing |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; NUS1 protein inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] Glucosamine results in increased expression of XBP1 protein alternative form 4-methylumbelliferone 8-carbaldehyde affects the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-methylumbelliferone 8-carbaldehyde inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 protein alternative form]; 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased splicing of XBP1 mRNA]; ERN1 protein affects the reaction [Glucosamine results in increased splicing of XBP1 mRNA] 4-phenylbutyric acid inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA]; ursodoxicoltaurine inhibits the reaction [Glucosamine results in increased expression of XBP1 mRNA] Glucosamine results in decreased splicing of XBP1 mRNA |
CTD |
PMID:19383982 PMID:20165829 PMID:30602124 PMID:33812996 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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Xdh |
xanthine dehydrogenase |
multiple interactions |
EXP |
[XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased abundance of Proteoglycans]; [XDH protein co-treated with Hypoxanthine] inhibits the reaction [Glucosamine results in increased expression of B3GAT3 mRNA] |
CTD |
PMID:11801247 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Zfp467 |
zinc finger protein 467 |
increases expression |
ISO |
Glucosamine results in increased expression of ZFP467 mRNA |
CTD |
PMID:17178593 |
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NCBI chr 4:77,385,752...77,394,709
Ensembl chr 4:77,385,758...77,392,229
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Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of ACSL1 mRNA |
CTD |
PMID:19520133 |
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NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of ALOX5 mRNA] |
CTD |
PMID:21877189 |
|
NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Cebpa |
CCAAT/enhancer binding protein alpha |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of CEBPA mRNA; glucosamine 6-O-sulfate results in decreased expression of CEBPA protein |
CTD |
PMID:19520133 |
|
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of CHUK protein] |
CTD |
PMID:21877189 |
|
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of FABP4 mRNA |
CTD |
PMID:19520133 |
|
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of FAS mRNA |
CTD |
PMID:19520133 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IKBKB protein] |
CTD |
PMID:21877189 |
|
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:21877189 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] |
CTD |
PMID:21877189 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Lep |
leptin |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of LEP mRNA |
CTD |
PMID:19520133 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipe |
lipase E, hormone sensitive type |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of LIPE mRNA |
CTD |
PMID:19520133 |
|
NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Lpl |
lipoprotein lipase |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of LPL mRNA |
CTD |
PMID:19520133 |
|
NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:21877189 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:21877189 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 protein] |
CTD |
PMID:21877189 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:21877189 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
CTD |
PMID:21877189 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Pla2g4a |
phospholipase A2 group 4A |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PLA2G4A protein] |
CTD |
PMID:21877189 |
|
NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266
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G |
Plin1 |
perilipin 1 |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of PLIN1 mRNA |
CTD |
PMID:19520133 |
|
NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of PPARG mRNA; glucosamine 6-O-sulfate results in decreased expression of PPARG protein |
CTD |
PMID:19520133 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
CTD |
PMID:21877189 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein] |
CTD |
PMID:21877189 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
decreases expression |
ISO |
glucosamine 6-O-sulfate results in decreased expression of SREBF1 mRNA; glucosamine 6-O-sulfate results in decreased expression of SREBF1 protein |
CTD |
PMID:19520133 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; glucosamine 6-O-sulfate inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] |
CTD |
PMID:21877189 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Chit1 |
chitinase 1 |
affects binding |
ISO |
CHIT1 protein binds to Chitin |
CTD |
PMID:16005164 |
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NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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G |
Igf1r |
insulin-like growth factor 1 receptor |
multiple interactions |
ISO |
[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of IGF1R mRNA |
CTD |
PMID:30041514 |
|
NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
[[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA |
CTD |
PMID:30041514 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Muc1 |
mucin 1, cell surface associated |
affects binding multiple interactions |
ISO |
[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of MMP9 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] which results in increased uptake of Docetaxel; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] which results in increased uptake of Protein Synthesis Inhibitors |
CTD |
PMID:30041514 |
|
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
ISO |
[[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of STAT3 mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of STAT3 mRNA |
CTD |
PMID:30041514 |
|
NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO |
[[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA]; [[Aptamers, Nucleotide binds to Chitin] which binds to MUC1 protein] promotes the reaction [[Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA]; [Docetaxel binds to Chitin] which results in decreased expression of VEGFA mRNA; [Protein Synthesis Inhibitors binds to Chitin] which results in decreased expression of VEGFA mRNA |
CTD |
PMID:30041514 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
multiple interactions |
ISO |
AKR1B1 protein promotes the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein] |
CTD |
PMID:30682331 |
|
NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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G |
Alb |
albumin |
multiple interactions |
ISO |
[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein; AKR1B1 protein promotes the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein]; sorbinil inhibits the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein] |
CTD |
PMID:30682331 |
|
NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein; AKR1B1 protein promotes the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein]; sorbinil inhibits the reaction [[ALB protein binds to Fructosamine] which results in increased secretion of TNF protein] |
CTD |
PMID:30682331 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
ISO |
Diatrizoate Meglumine results in increased expression of BAX protein |
CTD |
PMID:17173243 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression multiple interactions |
ISO EXP |
Diatrizoate Meglumine results in increased expression of BCL2 protein Diatrizoate Meglumine results in decreased expression of BCL2 mRNA Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in decreased expression of BCL2 mRNA] |
CTD |
PMID:17173243 PMID:28412091 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp12 |
caspase 12 |
increases cleavage |
EXP |
Diatrizoate Meglumine results in increased cleavage of CASP12 protein |
CTD |
PMID:20071420 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
increases activity increases expression multiple interactions |
ISO EXP |
Diatrizoate Meglumine results in increased activity of CASP3 protein Diatrizoate Meglumine results in increased expression of CASP3 mRNA [Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein; [sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein]; Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of CASP3 mRNA]; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein] |
CTD |
PMID:17173243 PMID:23335628 PMID:28412091 PMID:31173751 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ctf1 |
cardiotrophin 1 |
multiple interactions |
EXP |
CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased cleavage of CASP3 protein]; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein]; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein] |
CTD |
PMID:23335628 |
|
NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
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G |
Eif2a |
eukaryotic translation initiation factor 2A |
increases phosphorylation |
EXP |
Diatrizoate Meglumine results in increased phosphorylation of EIF2A protein |
CTD |
PMID:20071420 |
|
NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
increases phosphorylation |
EXP |
Diatrizoate Meglumine results in increased phosphorylation of EIF2AK3 protein |
CTD |
PMID:20071420 |
|
NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases expression |
EXP |
Diatrizoate Meglumine results in increased expression of GSTA2 mRNA |
CTD |
PMID:28412091 |
|
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
multiple interactions |
EXP |
[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of HAVCR1 protein] |
CTD |
PMID:23335628 |
|
NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hmox1 |
heme oxygenase 1 |
increases expression decreases expression multiple interactions |
EXP |
Diatrizoate Meglumine results in increased expression of HMOX1 mRNA Diatrizoate Meglumine results in decreased expression of HMOX1 protein Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of HMOX1 mRNA] |
CTD |
PMID:28412091 PMID:31173751 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
increases expression |
EXP |
Diatrizoate Meglumine results in increased expression of HSP90B1 protein |
CTD |
PMID:20071420 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Diatrizoate Meglumine results in increased expression of HSPA5 protein |
CTD |
PMID:20071420 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression |
EXP |
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 mRNA]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]]; sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein] Diatrizoate Meglumine results in increased expression of IL6 mRNA; Diatrizoate Meglumine results in increased expression of IL6 protein |
CTD |
PMID:28412091 PMID:31173751 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions decreases expression increases expression |
EXP |
Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of NFE2L2 mRNA]; NFE2L2 protein affects the reaction [[sulforaphane co-treated with Diatrizoate Meglumine] results in increased activity of CASP3 protein]; NFE2L2 protein affects the reaction [sulforaphane inhibits the reaction [Diatrizoate Meglumine results in increased expression of IL6 protein]] Diatrizoate Meglumine results in decreased expression of NFE2L2 protein |
CTD |
PMID:28412091 PMID:31173751 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
EXP |
[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein; CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein] |
CTD |
PMID:23335628 |
|
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Tp53 |
tumor protein p53 |
increases expression multiple interactions |
EXP |
Diatrizoate Meglumine results in increased expression of TP53 mRNA Lansoprazole inhibits the reaction [Diatrizoate Meglumine results in increased expression of TP53 mRNA] |
CTD |
PMID:28412091 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Angptl4 |
angiopoietin-like 4 |
increases expression decreases expression |
ISO |
Acetylglucosamine results in increased expression of ANGPTL4 mRNA Acetylglucosamine results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Ap1s3 |
adaptor related protein complex 1 subunit sigma 3 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of AP1S3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine] |
CTD |
PMID:39172838 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of ARHGDIB mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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G |
Arpc4 |
actin related protein 2/3 complex, subunit 4 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of ARPC4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
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G |
Calml5 |
calmodulin-like 5 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of CALML5 mRNA |
CTD |
PMID:18047607 |
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NCBI chr17:66,394,433...66,395,352
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G |
Cat |
catalase |
increases expression |
ISO |
Acetylglucosamine results in increased expression of CAT mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of CCT5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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|
G |
Cdkl1 |
cyclin dependent kinase like 1 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of CDKL1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
|
|
G |
Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
Acetylglucosamine results in increased expression of CES1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
|
|
G |
Dct |
dopachrome tautomerase |
increases expression |
ISO |
Acetylglucosamine results in increased expression of DCT mRNA |
CTD |
PMID:18047607 |
|
NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
|
|
G |
Diaph2 |
diaphanous-related formin 2 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of DIAPH2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr X:92,395,189...93,234,521
Ensembl chr X:92,395,251...93,229,869
|
|
G |
Eno2 |
enolase 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of ENO2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
|
|
G |
Fbxo10 |
F-box protein 10 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of FBXO10 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 5:59,297,016...59,343,429
Ensembl chr 5:59,297,045...59,343,348
|
|
G |
Fbxo4 |
F-box protein 4 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of FBXO4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792
|
|
G |
Fcnb |
ficolin B |
affects binding |
ISO |
FCN1 protein binds to Acetylglucosamine |
CTD |
PMID:11012776 |
|
NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of GPX1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Gsta4 |
glutathione S-transferase alpha 4 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of GSTA4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
|
|
G |
Gstt2 |
glutathione S-transferase theta 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of GSTT2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
|
|
G |
Hk2 |
hexokinase 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of HK2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
|
|
G |
Ifng |
interferon gamma |
increases expression increases secretion |
ISO |
Acetylglucosamine analog results in increased expression of IFNG mRNA Acetylglucosamine analog results in increased secretion of IFNG protein |
CTD |
PMID:21349367 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Il4 |
interleukin 4 |
increases expression |
ISO |
Acetylglucosamine analog results in increased expression of IL4 mRNA |
CTD |
PMID:21349367 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Klrb1a |
killer cell lectin like receptor B1A |
affects binding |
EXP |
Acetylglucosamine analog binds to KLRB1A protein |
CTD |
PMID:21349367 |
|
NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
|
|
G |
Odc1 |
ornithine decarboxylase 1 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of ODC1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
|
|
G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PFKFB3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
|
|
G |
Pon2 |
paraoxonase 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PON2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
[Acetylglucosamine co-treated with Glucose] binds to PPARA protein; Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] |
CTD |
PMID:18812576 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
|
|
G |
Ppp1r9a |
protein phosphatase 1, regulatory subunit 9A |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of PPP1R9A mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
|
|
G |
Prdx3 |
peroxiredoxin 3 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PRDX3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
|
|
G |
Prdx5 |
peroxiredoxin 5 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PRDX5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
|
|
G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine] |
CTD |
PMID:39172838 |
|
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
|
|
G |
Rbp1 |
retinol binding protein 1 |
decreases expression increases expression |
ISO |
Acetylglucosamine results in decreased expression of RBP1 mRNA Acetylglucosamine results in increased expression of RBP1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
|
|
G |
Sele |
selectin E |
affects binding |
ISO |
[Acetylglucosamine analog binds to Biotin] which binds to SELE protein; Acetylglucosamine analog binds to SELE protein |
CTD |
PMID:12191509 |
|
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
|
|
G |
Sell |
selectin L |
affects binding |
EXP |
[Acetylglucosamine analog binds to Biotin] which binds to SELL protein; Acetylglucosamine analog binds to SELL protein |
CTD |
PMID:12191509 |
|
NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
|
|
G |
Selp |
selectin P |
affects binding |
ISO |
[Acetylglucosamine analog binds to Biotin] which binds to SELP protein; Acetylglucosamine analog binds to SELP protein |
CTD |
PMID:12191509 |
|
NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
|
|
G |
Serpina3n |
serpin family A member 3N |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SERPINA3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
|
|
G |
Serpinb3a |
serpin family B member 3A |
increases expression |
ISO |
Acetylglucosamine results in increased expression of SERPINB4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
|
|
G |
Slc2a3 |
solute carrier family 2 member 3 |
decreases expression increases expression |
ISO |
Acetylglucosamine results in decreased expression of SLC2A3 mRNA Acetylglucosamine results in increased expression of SLC2A3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
|
|
G |
Slc7a5 |
solute carrier family 7 member 5 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SLC7A5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
|
|
G |
Snx5 |
sorting nexin 5 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SNX5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192
|
|
G |
Sod2 |
superoxide dismutase 2 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SOD2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
|
|
G |
Tgm5 |
transglutaminase 5 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of TGM5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 3:108,008,087...108,044,013
Ensembl chr 3:108,008,143...108,043,976
|
|
G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 |
|
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
|
|
G |
Ttll3 |
tubulin tyrosine ligase like 3 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of TTLL3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
|
|
G |
Tubb5 |
tubulin, beta 5 class I |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of TUBB mRNA |
CTD |
PMID:18047607 |
|
NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
|
|
G |
Tubgcp3 |
tubulin gamma complex component 3 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of TUBGCP3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
|
|
G |
Ube2d3 |
ubiquitin-conjugating enzyme E2D 3 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of UBE2D3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
|
|
|
G |
Angptl4 |
angiopoietin-like 4 |
increases expression decreases expression |
ISO |
Acetylglucosamine results in increased expression of ANGPTL4 mRNA Acetylglucosamine results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
|
|
G |
Ap1s3 |
adaptor related protein complex 1 subunit sigma 3 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of AP1S3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 9:80,950,402...81,009,889
Ensembl chr 9:80,950,715...81,009,798
|
|
G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine] |
CTD |
PMID:39172838 |
|
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
|
|
G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of ARHGDIB mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
|
|
G |
Arpc4 |
actin related protein 2/3 complex, subunit 4 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of ARPC4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785
|
|
G |
Calml5 |
calmodulin-like 5 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of CALML5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr17:66,394,433...66,395,352
|
|
G |
Cat |
catalase |
increases expression |
ISO |
Acetylglucosamine results in increased expression of CAT mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
|
|
G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of CCT5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
|
|
G |
Cdkl1 |
cyclin dependent kinase like 1 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of CDKL1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
|
|
G |
Ces1d |
carboxylesterase 1D |
increases expression |
ISO |
Acetylglucosamine results in increased expression of CES1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
|
|
G |
Dct |
dopachrome tautomerase |
increases expression |
ISO |
Acetylglucosamine results in increased expression of DCT mRNA |
CTD |
PMID:18047607 |
|
NCBI chr15:95,062,006...95,100,863
Ensembl chr15:95,062,003...95,100,836
|
|
G |
Diaph2 |
diaphanous-related formin 2 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of DIAPH2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr X:92,395,189...93,234,521
Ensembl chr X:92,395,251...93,229,869
|
|
G |
Eno2 |
enolase 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of ENO2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
|
|
G |
Fbxo10 |
F-box protein 10 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of FBXO10 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 5:59,297,016...59,343,429
Ensembl chr 5:59,297,045...59,343,348
|
|
G |
Fbxo4 |
F-box protein 4 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of FBXO4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 2:53,174,798...53,187,792
Ensembl chr 2:53,174,798...53,187,792
|
|
G |
Fcnb |
ficolin B |
affects binding |
ISO |
FCN1 protein binds to Acetylglucosamine |
CTD |
PMID:11012776 |
|
NCBI chr 3:11,393,713...11,402,198
Ensembl chr 3:11,393,739...11,402,151
|
|
G |
Gpx1 |
glutathione peroxidase 1 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of GPX1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
|
|
G |
Gsta4 |
glutathione S-transferase alpha 4 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of GSTA4 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
|
|
G |
Gstt2 |
glutathione S-transferase theta 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of GSTT2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288
|
|
G |
Hk2 |
hexokinase 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of HK2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530
|
|
G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 |
|
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
|
|
G |
Ifng |
interferon gamma |
increases expression increases secretion |
ISO |
Acetylglucosamine analog results in increased expression of IFNG mRNA Acetylglucosamine analog results in increased secretion of IFNG protein |
CTD |
PMID:21349367 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
|
|
G |
Il4 |
interleukin 4 |
increases expression |
ISO |
Acetylglucosamine analog results in increased expression of IL4 mRNA |
CTD |
PMID:21349367 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Klrb1a |
killer cell lectin like receptor B1A |
affects binding |
EXP |
Acetylglucosamine analog binds to KLRB1A protein |
CTD |
PMID:21349367 |
|
NCBI chr 4:161,890,577...161,904,050
Ensembl chr 4:161,890,577...161,961,675
|
|
G |
Odc1 |
ornithine decarboxylase 1 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of ODC1 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
|
|
G |
Pfkfb3 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PFKFB3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
|
|
G |
Pon2 |
paraoxonase 2 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PON2 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
|
|
G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions |
ISO |
[Acetylglucosamine co-treated with Glucose] binds to PPARA protein; Acetylglucosamine inhibits the reaction [Glucose inhibits the reaction [Palmitoyl Coenzyme A analog binds to PPARA protein]] |
CTD |
PMID:18812576 |
|
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
|
|
G |
Ppp1r9a |
protein phosphatase 1, regulatory subunit 9A |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of PPP1R9A mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907
|
|
G |
Prdx3 |
peroxiredoxin 3 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PRDX3 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
|
|
G |
Prdx5 |
peroxiredoxin 5 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of PRDX5 mRNA |
CTD |
PMID:18047607 |
|
NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
|
|
G |
Psen1 |
presenilin 1 |
multiple interactions |
ISO |
[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of Acetylglucosamine] |
CTD |
PMID:39172838 |
|
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
|
|
G |
Rbp1 |
retinol binding protein 1 |
decreases expression increases expression |
ISO |
Acetylglucosamine results in decreased expression of RBP1 mRNA Acetylglucosamine results in increased expression of RBP1 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 8:99,025,218...99,046,740
Ensembl chr 8:99,025,206...99,046,743
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G |
Sele |
selectin E |
affects binding |
ISO |
[Acetylglucosamine analog binds to Biotin] which binds to SELE protein; Acetylglucosamine analog binds to SELE protein |
CTD |
PMID:12191509 |
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NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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G |
Sell |
selectin L |
affects binding |
EXP |
[Acetylglucosamine analog binds to Biotin] which binds to SELL protein; Acetylglucosamine analog binds to SELL protein |
CTD |
PMID:12191509 |
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NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
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G |
Selp |
selectin P |
affects binding |
ISO |
[Acetylglucosamine analog binds to Biotin] which binds to SELP protein; Acetylglucosamine analog binds to SELP protein |
CTD |
PMID:12191509 |
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NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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G |
Serpina3n |
serpin family A member 3N |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SERPINA3 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
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G |
Serpinb3a |
serpin family B member 3A |
increases expression |
ISO |
Acetylglucosamine results in increased expression of SERPINB4 mRNA |
CTD |
PMID:18047607 |
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NCBI chr13:23,241,303...23,246,328
Ensembl chr13:23,236,972...23,246,985
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G |
Slc2a3 |
solute carrier family 2 member 3 |
increases expression decreases expression |
ISO |
Acetylglucosamine results in increased expression of SLC2A3 mRNA Acetylglucosamine results in decreased expression of SLC2A3 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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G |
Slc7a5 |
solute carrier family 7 member 5 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SLC7A5 mRNA |
CTD |
PMID:18047607 |
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NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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G |
Snx5 |
sorting nexin 5 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SNX5 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 3:131,621,875...131,641,127
Ensembl chr 3:131,621,880...131,641,192
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G |
Sod2 |
superoxide dismutase 2 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of SOD2 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Tgm5 |
transglutaminase 5 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of TGM5 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 3:108,008,087...108,044,013
Ensembl chr 3:108,008,143...108,043,976
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
Acetylglucosamine inhibits the reaction [TNF results in increased expression of ICAM1 protein] |
CTD |
PMID:16431966 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Ttll3 |
tubulin tyrosine ligase like 3 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of TTLL3 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 4:146,532,958...146,558,425
Ensembl chr 4:146,533,953...146,557,889
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G |
Tubb5 |
tubulin, beta 5 class I |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of TUBB mRNA |
CTD |
PMID:18047607 |
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NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940
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G |
Tubgcp3 |
tubulin gamma complex component 3 |
decreases expression |
ISO |
Acetylglucosamine results in decreased expression of TUBGCP3 mRNA |
CTD |
PMID:18047607 |
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NCBI chr16:76,851,859...76,912,499
Ensembl chr16:76,851,810...76,912,499
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G |
Ube2d3 |
ubiquitin-conjugating enzyme E2D 3 |
increases expression |
ISO |
Acetylglucosamine results in increased expression of UBE2D3 mRNA |
CTD |
PMID:18047607 |
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NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081
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G |
Cmas |
cytidine monophosphate N-acetylneuraminic acid synthetase |
affects abundance |
ISO |
CMAS protein affects the abundance of N-acetylmannosamine |
CTD |
PMID:27380425 |
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NCBI chr 4:175,718,808...175,737,128
Ensembl chr 4:175,718,808...175,737,125
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G |
A2m |
alpha-2-macroglobulin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of A2M mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions |
EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ABCA1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ABCA1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ABCA1 mRNA |
CTD |
PMID:35786680 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
increases activity increases expression |
EXP ISO |
Streptozocin results in increased activity of ABCB11 protein Streptozocin results in increased expression of ABCB11 protein |
CTD |
PMID:12055592 PMID:23319174 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
decreases expression increases expression |
ISO |
Streptozocin results in decreased expression of ABCB1B mRNA; Streptozocin results in decreased expression of ABCB1B protein Streptozocin results in increased expression of ABCB1B protein |
CTD |
PMID:22531820 PMID:23319174 |
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NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
increases expression |
EXP |
Streptozocin results in increased expression of ABCB4 mRNA; Streptozocin results in increased expression of ABCB4 protein |
CTD |
PMID:12055592 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
increases expression |
ISO |
Streptozocin results in increased expression of ABCC1 mRNA; Streptozocin results in increased expression of ABCC1 protein |
CTD |
PMID:22531820 PMID:23319174 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
increases expression |
EXP ISO |
Streptozocin results in increased expression of ABCC2 mRNA Streptozocin results in increased expression of ABCC2 mRNA; Streptozocin results in increased expression of ABCC2 protein |
CTD |
PMID:11752103 PMID:22531820 PMID:23319174 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc3 |
ATP binding cassette subfamily C member 3 |
decreases expression increases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of ABCC3 mRNA Streptozocin results in increased expression of ABCC3 mRNA; Streptozocin results in increased expression of ABCC3 protein [resveratrol co-treated with Streptozocin] results in increased expression of ABCC3 mRNA |
CTD |
PMID:22531820 PMID:23319174 PMID:25905778 |
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NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
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G |
Abcc4 |
ATP binding cassette subfamily C member 4 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ABCC4 mRNA; Streptozocin results in increased expression of ABCC4 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of ABCC4 mRNA |
CTD |
PMID:22531820 PMID:23319174 PMID:29382564 |
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NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
increases expression |
ISO |
Streptozocin results in increased expression of ABCC5 mRNA; Streptozocin results in increased expression of ABCC5 protein |
CTD |
PMID:22531820 PMID:23319174 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
decreases expression |
ISO |
Streptozocin results in decreased expression of ABCC6 protein |
CTD |
PMID:22531820 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression |
ISO |
Streptozocin results in increased expression of ABCG2 mRNA; Streptozocin results in increased expression of ABCG2 protein |
CTD |
PMID:23319174 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
increases expression |
ISO |
Streptozocin results in increased expression of ABCG5 mRNA |
CTD |
PMID:23319174 |
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NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
increases expression |
ISO |
Streptozocin results in increased expression of ABCG8 mRNA |
CTD |
PMID:23319174 |
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NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Abhd2 |
abhydrolase domain containing 2, acylglycerol lipase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ABHD2 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:133,217,403...133,298,564
Ensembl chr 1:133,217,375...133,299,061
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions decreases expression decreases activity increases expression |
EXP ISO |
Fructose inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Fructose inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased activity of ACACA protein]; Triiodothyronine inhibits the reaction [Streptozocin results in decreased expression of ACACA mRNA] Streptozocin results in increased expression of ACACA mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA] |
CTD |
PMID:1973097 PMID:28822685 PMID:33812996 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ACADM protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACADM protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of ACAT1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACAT1 protein] Acrylamide inhibits the reaction [Streptozocin results in decreased expression of ACAT1 mRNA] |
CTD |
PMID:19634143 PMID:34896238 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Acbd6 |
acyl-CoA binding domain containing 6 |
increases expression |
EXP |
Streptozocin results in increased expression of ACBD6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:67,726,786...67,863,392
Ensembl chr13:67,726,786...67,862,311
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions increases expression increases activity |
EXP ISO |
[INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ACE protein] Streptozocin results in increased expression of ACE mRNA; Streptozocin results in increased expression of ACE protein Streptozocin results in increased activity of ACE protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA]; [Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of ACE mRNA] |
CTD |
PMID:15793251 PMID:16979161 PMID:22191573 PMID:23733546 PMID:28468961 PMID:29266779 PMID:29682576 PMID:37120126 More...
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin converting enzyme 2 |
decreases expression multiple interactions increases activity |
ISO EXP |
Streptozocin results in decreased expression of ACE2 protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; [Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ACE2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein] [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein] Streptozocin results in increased activity of ACE2 protein |
CTD |
PMID:20844835 PMID:21381899 PMID:28468961 PMID:29266779 PMID:29682576 PMID:37120126 More...
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Acer2 |
alkaline ceramidase 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of ACER2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:101,391,830...101,442,615
Ensembl chr 5:101,391,885...101,442,614
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G |
Ache |
acetylcholinesterase |
multiple interactions increases activity decreases activity |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein]]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Alendronate inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Curcumin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Genistein inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Indinavir inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Physostigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of ACHE protein] [Fructose co-treated with Streptozocin] results in increased expression of ACHE protein; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased activity of ACHE protein; [Propolis co-treated with Streptozocin] inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein; alpha-Tocopherol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Canagliflozin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of ACHE protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; Donepezil inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; geraniol inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Melatonin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Propolis inhibits the reaction [Streptozocin results in decreased activity of ACHE protein]; pyrazolanthrone inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Streptozocin promotes the reaction [[Propolis co-treated with Chlorpyrifos] results in decreased activity of ACHE protein]; Tocotrienols inhibits the reaction [Streptozocin results in increased activity of ACHE protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of ACHE protein] |
CTD |
PMID:18208924 PMID:18343489 PMID:19464315 PMID:19705549 PMID:20369229 PMID:20600246 PMID:23060470 PMID:24752916 PMID:27087133 PMID:27566243 PMID:28259689 PMID:28499986 PMID:30120923 PMID:30481507 PMID:31400774 PMID:32805344 PMID:33823243 PMID:37354076 More...
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NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Acmsd |
aminocarboxymuconate semialdehyde decarboxylase |
increases activity increases expression |
EXP |
Streptozocin results in increased activity of ACMSD protein Streptozocin results in increased expression of ACMSD mRNA |
CTD |
PMID:12042425 |
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NCBI chr13:39,200,412...39,245,954
Ensembl chr13:39,200,314...39,245,209
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G |
Aco2 |
aconitase 2 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ACO2 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ACO2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
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G |
Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acot2 |
acyl-CoA thioesterase 2 |
multiple interactions |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of ACOT2 mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT2 mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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G |
Acot9 |
acyl-CoA thioesterase 9 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACOT9 mRNA |
CTD |
PMID:29127188 |
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NCBI chr X:40,073,197...40,123,573
Ensembl chr X:40,064,810...40,123,559
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G |
Acox1 |
acyl-CoA oxidase 1 |
multiple interactions |
EXP |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ACOX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of ACOX1 mRNA |
CTD |
PMID:35786680 |
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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G |
Acp5 |
acid phosphatase 5, tartrate resistant |
increases expression multiple interactions increases activity |
ISO |
Streptozocin results in increased expression of ACP5 mRNA formononetin inhibits the reaction [Streptozocin results in increased activity of ACP5 protein]; formononetin inhibits the reaction [Streptozocin results in increased expression of ACP5 mRNA] |
CTD |
PMID:35315182 |
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NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
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G |
Acsm2 |
acyl-CoA synthetase medium-chain family member 2 |
increases expression |
EXP |
Streptozocin results in increased expression of ACSM2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:173,916,368...173,955,116
Ensembl chr 1:173,916,368...173,955,116
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G |
Acss1 |
acyl-CoA synthetase short-chain family member 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ACSS1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression decreases expression |
EXP ISO |
[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of ACTA2 protein]] [Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA]; [Streptozocin co-treated with fatostatin] results in increased expression of ACTA2 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of ACTA2 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ACTA2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACTA2 mRNA] Streptozocin results in increased expression of ACTA2 protein |
CTD |
PMID:29420703 PMID:29988851 PMID:30551545 PMID:35051763 PMID:35993117 PMID:38282657 More...
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actc1 |
actin, alpha, cardiac muscle 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of ACTC1 protein |
CTD |
PMID:21136691 |
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NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
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G |
Actn4 |
actinin alpha 4 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ACTN4 protein Trientine inhibits the reaction [Streptozocin results in increased expression of ACTN4 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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G |
Acy1 |
aminoacylase 1 |
multiple interactions decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of ACY1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682
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G |
Ada |
adenosine deaminase |
increases activity multiple interactions |
EXP |
Streptozocin results in increased activity of ADA protein [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in increased activity of ADA protein] |
CTD |
PMID:32864810 |
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NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ADAM17 mRNA; Streptozocin results in increased expression of ADAM17 protein Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of ADAM17 protein] |
CTD |
PMID:35305976 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adgre1 |
adhesion G protein-coupled receptor E1 |
multiple interactions increases expression |
EXP ISO |
stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of ADGRE1 protein]] [fatostatin co-treated with Streptozocin] results in increased expression of ADGRE1 mRNA Streptozocin results in increased expression of ADGRE1 mRNA |
CTD |
PMID:23611540 PMID:29420703 |
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NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
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G |
Adgrg7 |
adhesion G protein-coupled receptor G7 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ADGRG7 mRNA |
CTD |
PMID:33484791 |
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NCBI chr11:43,808,101...43,877,539
Ensembl chr11:43,813,801...43,876,316
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G |
Adh1c |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
increases expression |
EXP |
Streptozocin results in increased expression of ADH1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions decreases expression decreases secretion |
EXP ISO |
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased secretion of ADIPOQ protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; geraniol promotes the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of ADIPOQ protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of ADIPOQ protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] Streptozocin results in decreased expression of ADIPOQ mRNA; Streptozocin results in decreased expression of ADIPOQ protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of ADIPOQ protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; omaveloxolone analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ADIPOQ protein] |
CTD |
PMID:17270171 PMID:21439372 PMID:21912612 PMID:22675305 PMID:24854284 PMID:27488359 PMID:28178614 PMID:29274332 PMID:29988851 PMID:32410268 PMID:37337224 PMID:37482253 More...
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor1 |
adiponectin receptor 1 |
decreases expression multiple interactions increases expression |
EXP |
Streptozocin results in decreased expression of ADIPOR1 protein 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of ADIPOR1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of ADIPOR1 protein] |
CTD |
PMID:17270171 PMID:24413998 PMID:29274332 |
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NCBI chr13:45,859,461...45,879,248
Ensembl chr13:45,859,533...45,879,241
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G |
Adipor2 |
adiponectin receptor 2 |
multiple interactions decreases expression |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]] |
CTD |
PMID:21912612 |
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NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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G |
Adora2a |
adenosine A2a receptor |
increases expression |
ISO |
Streptozocin results in increased expression of ADORA2A protein |
CTD |
PMID:26654777 |
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NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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G |
Adra1a |
adrenoceptor alpha 1A |
increases expression |
EXP |
Streptozocin results in increased expression of ADRA1A mRNA; Streptozocin results in increased expression of ADRA1A protein |
CTD |
PMID:19133277 |
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NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500
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G |
Adra1b |
adrenoceptor alpha 1B |
increases expression |
EXP |
Streptozocin results in increased expression of ADRA1B mRNA |
CTD |
PMID:19298542 |
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NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
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G |
Adra1d |
adrenoceptor alpha 1D |
decreases expression |
EXP |
Streptozocin results in decreased expression of ADRA1D mRNA |
CTD |
PMID:19298542 |
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NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354
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G |
Adrb1 |
adrenoceptor beta 1 |
multiple interactions decreases expression |
EXP |
Metoprolol inhibits the reaction [Streptozocin results in decreased expression of ADRB1 protein] |
CTD |
PMID:18703049 |
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NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259
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G |
Adrb2 |
adrenoceptor beta 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ADRB2 protein Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB2 protein] |
CTD |
PMID:18703049 |
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NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Adrb3 |
adrenoceptor beta 3 |
multiple interactions increases expression |
EXP |
Metoprolol promotes the reaction [Streptozocin results in increased expression of ADRB3 protein] |
CTD |
PMID:18703049 |
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NCBI chr16:64,839,820...64,844,552
Ensembl chr16:64,841,788...64,844,552
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G |
Afmid |
arylformamidase |
increases expression |
EXP |
Streptozocin results in increased expression of AFMID mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
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G |
Afp |
alpha-fetoprotein |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of AFP mRNA |
CTD |
PMID:29127188 |
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NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
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G |
Ager |
advanced glycosylation end product-specific receptor |
increases expression multiple interactions increases response to substance |
EXP ISO |
Streptozocin results in increased expression of AGER mRNA; Streptozocin results in increased expression of AGER protein [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGER protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of AGER protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of AGER mRNA] manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of AGER mRNA] AGER protein results in increased susceptibility to Streptozocin |
CTD |
PMID:19397970 PMID:19833897 PMID:22476978 PMID:25199697 PMID:27109771 PMID:31009641 PMID:36999408 More...
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Agrp |
agouti related neuropeptide |
multiple interactions increases expression |
EXP |
INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA] |
CTD |
PMID:20219977 |
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NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584
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G |
Agt |
angiotensinogen |
multiple interactions increases expression decreases abundance |
ISO EXP |
CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; Valsartan inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGT protein] ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; AGT protein modified form inhibits the reaction [Streptozocin results in decreased abundance of Cyclic GMP]; AGT protein modified form inhibits the reaction [Streptozocin results in increased expression of PDE5 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGT protein] Streptozocin results in increased expression of AGT mRNA; Streptozocin results in increased expression of AGT protein; Streptozocin results in increased expression of AGT protein modified form |
CTD |
PMID:11375343 PMID:15643138 PMID:17724226 PMID:18487452 PMID:20547220 PMID:20844835 PMID:28299329 PMID:28468961 PMID:29266779 More...
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions increases expression |
ISO EXP |
2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; [Perindopril co-treated with AM6545] inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; [Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of AGTR1A protein]; Valsartan promotes the reaction [Streptozocin results in increased expression of AGTR1 protein] Streptozocin results in increased expression of AGTR1 protein; Streptozocin results in increased expression of AGTR1A mRNA; Streptozocin results in increased expression of AGTR1A protein [Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR1A mRNA] |
CTD |
PMID:17724226 PMID:18487452 PMID:21381899 PMID:28946194 PMID:29266779 PMID:30184259 PMID:37120126 More...
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NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Agtr2 |
angiotensin II receptor, type 2 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of AGTR2 mRNA; Streptozocin results in increased expression of AGTR2 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; esculetin promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of AGTR2 mRNA] CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein] |
CTD |
PMID:15587404 PMID:17724226 PMID:28946194 PMID:29266779 |
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NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G |
Agxt2 |
alanine-glyoxylate aminotransferase 2 |
multiple interactions decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of AGXT2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
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G |
Ahcy |
adenosylhomocysteinase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of AHCY mRNA; [Streptozocin co-treated with Dietary Fats] results in increased methylation of AHCY gene |
CTD |
PMID:29127188 |
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NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393
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G |
Ahr |
aryl hydrocarbon receptor |
decreases expression |
ISO |
Streptozocin results in decreased expression of AHR mRNA |
CTD |
PMID:22531820 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of AIFM1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of AIFM1 protein] [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1] |
CTD |
PMID:19634143 PMID:23458895 PMID:23499715 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Ajm1 |
apical junction component 1 homolog |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AJM1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:8,394,942...8,401,323
Ensembl chr 3:8,392,889...8,401,321
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G |
Ak4 |
adenylate kinase 4 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of AK4 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of AK4 protein] |
CTD |
PMID:19634143 |
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NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
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G |
Akr1a1 |
aldo-keto reductase family 1 member A1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of AKR1A1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of AKR1A1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
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G |
Akr1b1 |
aldo-keto reductase family 1 member B1 |
multiple interactions |
ISO |
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein]; Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:25541468 |
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NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
multiple interactions |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of AKR1C3 mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of AKR1C18 mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
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G |
Akr7a3 |
aldo-keto reductase family 7 member A3 |
increases expression |
EXP |
Streptozocin results in increased expression of AKR7A3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases expression decreases phosphorylation increases phosphorylation increases expression decreases expression |
EXP ISO |
[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein; [Resveratrol co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of AKT1 mRNA]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of AKT1 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of AKT1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased phosphorylation of AKT1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of AKT1 mRNA]] Streptozocin results in decreased expression of AKT1 mRNA; Streptozocin results in decreased expression of AKT1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of AKT1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased phosphorylation of AKT1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of AKT1 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT1 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of AKT1 protein] streptozocin increases phosphorylation of Akt1 protein in heart Streptozotocin decreases expression of Akt1 protein in the liver Streptozocin decreases phosphorylation of Akt1 protein in the liver |
CTD RGD |
PMID:16595661 PMID:19002579 PMID:22675305 PMID:24810525 PMID:25541178 PMID:26071184 PMID:26286522 PMID:27417257 PMID:30721768 PMID:31743741 PMID:31877369 PMID:32805344 PMID:33359794 PMID:33484791 PMID:33724628 PMID:34391751 PMID:34649470 PMID:35414346 PMID:35442559 PMID:36169646 PMID:36627075 PMID:37081038 PMID:37566541 PMID:38706688 PMID:36044268 PMID:30186875 PMID:29379801 More...
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RGD:156430337, RGD:14401598, RGD:408346751 |
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of AKT2 protein] |
CTD |
PMID:27270450 |
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NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Alad |
aminolevulinate dehydratase |
multiple interactions |
ISO |
[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein; alpha-Tocopherol inhibits the reaction [[Streptozocin results in increased abundance of Blood Glucose] which results in decreased expression of ALAD protein] |
CTD |
PMID:7728901 |
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NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
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G |
Alas1 |
5'-aminolevulinate synthase 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ALAS1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of ALAS1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
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G |
Alb |
albumin |
multiple interactions increases secretion decreases expression increases expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in increased expression of ALB protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ALB protein]; TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein] [bisphenol A co-treated with Streptozocin] results in decreased expression of ALB protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein; [Streptozocin co-treated with Cadmium] results in increased expression of ALB protein; [Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Eugenol inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased expression of ALB protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased secretion of ALB protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of ALB protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; LR-90 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of ALB protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of ALB protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ALB protein] |
CTD |
PMID:12845431 PMID:14871415 PMID:17360766 PMID:18204486 PMID:21450970 PMID:24923654 PMID:25199697 PMID:25240712 PMID:29331653 PMID:30184259 PMID:31063766 PMID:33639173 PMID:34922902 PMID:35187753 PMID:36510688 PMID:38047382 More...
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
increases expression |
EXP |
Streptozocin results in increased expression of ALDH1A1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldh1a3 |
aldehyde dehydrogenase 1 family, member A3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ALDH1A3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
increases expression decreases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ALDH2 protein Streptozocin results in decreased expression of ALDH2 mRNA; Streptozocin results in decreased expression of ALDH2 protein Ethanol inhibits the reaction [Streptozocin results in decreased expression of ALDH2] |
CTD |
PMID:21136691 PMID:23500772 |
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NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
Aldob |
aldolase, fructose-bisphosphate B |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ALDOB protein Trientine inhibits the reaction [Streptozocin results in increased expression of ALDOB protein] |
CTD |
PMID:19634143 |
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NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116
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G |
Alkbh3 |
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ALKBH3 mRNA |
CTD |
PMID:20665664 |
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NCBI chr 3:79,939,515...79,972,820
Ensembl chr 3:79,939,600...79,972,000
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G |
Alox5ap |
arachidonate 5-lipoxygenase activating protein |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ALOX5AP mRNA |
CTD |
PMID:29127188 |
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NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
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G |
Alpk1 |
alpha-kinase 1 |
multiple interactions increases response to substance |
ISO |
[ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein; ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein]; ALPK1 protein promotes the reaction [Streptozocin results in increased abundance of Blood Glucose] |
CTD |
PMID:27542954 |
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NCBI chr 2:216,126,939...216,247,180
Ensembl chr 2:216,128,825...216,247,157
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G |
Ambn |
ameloblastin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of AMBN mRNA |
CTD |
PMID:33484791 |
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NCBI chr14:19,601,761...19,614,382
Ensembl chr14:19,601,702...19,614,393
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G |
Angpt1 |
angiopoietin 1 |
increases expression decreases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ANGPT1 mRNA; Streptozocin results in increased expression of ANGPT1 protein Streptozocin results in decreased expression of ANGPT1 mRNA baicalin inhibits the reaction [Streptozocin results in decreased expression of ANGPT1 mRNA] |
CTD |
PMID:15643138 PMID:19958114 PMID:34414639 |
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NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067
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G |
Angpt2 |
angiopoietin 2 |
multiple interactions increases expression |
EXP |
Enalapril inhibits the reaction [Streptozocin results in increased expression of ANGPT2 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of ANGPT2 protein] Streptozocin results in increased expression of ANGPT2 mRNA; Streptozocin results in increased expression of ANGPT2 protein |
CTD |
PMID:15643138 PMID:19958114 PMID:20821229 |
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NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of ANGPTL4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Ankrd1 |
ankyrin repeat domain 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ANKRD1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ANKRD1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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G |
Ankrd2 |
ankyrin repeat domain 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ANKRD2 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:240,847,111...240,856,563
Ensembl chr 1:240,847,072...240,856,566
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G |
Anpep |
alanyl aminopeptidase, membrane |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ANPEP protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ANPEP protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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G |
Anxa3 |
annexin A3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ANXA3 protein [resveratrol co-treated with Streptozocin] results in increased expression of ANXA3 mRNA; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA3 protein] |
CTD |
PMID:21136691 PMID:25905778 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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G |
Anxa5 |
annexin A5 |
decreases expression increases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ANXA5 protein Streptozocin results in increased expression of ANXA5 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ANXA5 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of ANXA5 protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Apex1 |
apurinic/apyrimidinic endodeoxyribonuclease 1 |
increases response to substance |
ISO |
APEX1 protein mutant form results in increased susceptibility to Streptozocin |
CTD |
PMID:19470598 |
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NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of APOA1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoa4 |
apolipoprotein A4 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of APOA4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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G |
Apob |
apolipoprotein B |
multiple interactions |
EXP |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of APOB mRNA |
CTD |
PMID:35786680 |
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoe |
apolipoprotein E |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of APOE mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of APOE mRNA] [Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine] |
CTD |
PMID:16380481 PMID:16684804 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions increases expression |
EXP ISO |
Memantine inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] Streptozocin results in increased expression of APP mRNA; Streptozocin results in increased expression of APP protein; Streptozocin results in increased expression of APP protein modified form 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of APP protein modified form]; Alendronate inhibits the reaction [Streptozocin results in increased expression of APP protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of APP protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of APP protein modified form] |
CTD |
PMID:21069392 PMID:21290839 PMID:30481507 PMID:34428446 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Aqp1 |
aquaporin 1 |
multiple interactions decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of AQP1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
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G |
Aqp7 |
aquaporin 7 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of AQP7 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of AQP7 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
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G |
Aqp9 |
aquaporin 9 |
increases expression |
EXP |
Streptozocin results in increased expression of AQP9 protein |
CTD |
PMID:22114114 |
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NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
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G |
Arg1 |
arginase 1 |
multiple interactions increases expression decreases expression increases activity |
ISO EXP |
[NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; Perindopril inhibits the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of ARG1 mRNA]] Streptozocin results in increased expression of ARG1 protein Streptozocin results in increased activity of ARG1 protein |
CTD |
PMID:29059224 PMID:29673160 PMID:30184259 PMID:34039237 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Arhgap9 |
Rho GTPase activating protein 9 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of ARHGAP9 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:63,148,573...63,157,025
Ensembl chr 7:63,148,900...63,157,524
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G |
Asns |
asparagine synthetase (glutamine-hydrolyzing) |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of ASNS mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
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G |
Atf2 |
activating transcription factor 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ATF2 protein resveratrol inhibits the reaction [Streptozocin results in increased expression of ATF2 protein] |
CTD |
PMID:26499206 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Atf3 |
activating transcription factor 3 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of ATF3 protein |
CTD |
PMID:38282657 |
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NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions increases expression increases phosphorylation |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ATF4 protein] Streptozocin results in increased phosphorylation of ATF4 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased phosphorylation of ATF4 protein] |
CTD |
PMID:24967692 PMID:30980806 PMID:33812996 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atf5 |
activating transcription factor 5 |
decreases expression |
EXP |
Streptozocin results in decreased expression of ATF5 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
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G |
Atf6 |
activating transcription factor 6 |
increases cleavage multiple interactions increases expression |
EXP ISO |
Streptozocin results in increased cleavage of ATF6 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of ATF6 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ATF6 protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA] streptozocin increases expression of Atf6 protein in heart |
CTD RGD |
PMID:30980806 PMID:33812996 PMID:34801538 PMID:36044268 |
RGD:156430337 |
NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg12 |
autophagy related 12 |
increases expression |
ISO |
Streptozocin results in increased expression of ATG12 mRNA |
CTD |
PMID:24889822 |
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NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418
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G |
Atg5 |
autophagy related 5 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of ATG5 mRNA [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of ATG5 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of ATG5 mRNA Streptozocin results in increased expression of ATG5 protein |
CTD |
PMID:24889822 PMID:35786680 PMID:38706688 |
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atox1 |
antioxidant 1 copper chaperone |
decreases expression |
EXP |
Streptozocin results in decreased expression of ATOX1 protein |
CTD |
PMID:24927960 |
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NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950
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G |
Atp2a2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
decreases activity multiple interactions decreases expression |
EXP ISO |
Streptozocin results in decreased activity of ATP2A2 protein [bisphenol A co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of ATP2A2 mRNA Streptozocin results in decreased expression of ATP2A2 mRNA Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of ATP2A2 protein] Streptozocin results in decreased expression of ATP2A2 mRNA; Streptozocin results in decreased expression of ATP2A2 protein |
CTD |
PMID:16685413 PMID:19000375 PMID:29935216 |
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NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
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G |
Atp2a3 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with bisphenol A] results in decreased expression of ATP2A3 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of ATP2A3 mRNA |
CTD |
PMID:29935216 |
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NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
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G |
Atp2b1 |
ATPase plasma membrane Ca2+ transporting 1 |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with bisphenol A] results in increased expression of ATP2B1 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of ATP2B1 mRNA Streptozocin results in increased expression of ATP2B1 mRNA |
CTD |
PMID:29935216 |
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NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
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G |
Atp5f1a |
ATP synthase F1 subunit alpha |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ATP5F1A protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1A protein] |
CTD |
PMID:21136691 |
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NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794
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G |
Atp5f1b |
ATP synthase F1 subunit beta |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ATP5F1B protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5F1B protein] |
CTD |
PMID:21136691 |
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NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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G |
Atp5mf |
ATP synthase membrane subunit f |
increases expression multiple interactions affects expression |
EXP ISO |
Streptozocin results in increased expression of ATP5MF protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5MF protein] Streptozocin affects the expression of ATP5MF mRNA |
CTD |
PMID:18583417 PMID:19634143 |
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NCBI chr12:9,421,665...9,428,236
Ensembl chr12:9,421,579...9,428,236
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G |
Atp5po |
ATP synthase peripheral stalk subunit OSCP |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ATP5PO protein Trientine inhibits the reaction [Streptozocin results in increased expression of ATP5PO protein] |
CTD |
PMID:19634143 |
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NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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G |
Atp6ap2 |
ATPase H+ transporting accessory protein 2 |
multiple interactions increases expression |
EXP |
(3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; (3,4-dihydroxyphenylamino)-2-imidazoline inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ATP6AP2 protein] Streptozocin results in increased expression of ATP6AP2 mRNA; Streptozocin results in increased expression of ATP6AP2 protein |
CTD |
PMID:18192338 |
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NCBI chr X:10,183,983...10,210,948
Ensembl chr X:10,183,068...10,210,918
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G |
Atp7a |
ATPase copper transporting alpha |
multiple interactions decreases expression |
ISO |
ATP7A gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; ATP7A protein inhibits the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] |
CTD |
PMID:23884884 |
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NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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G |
Atp7b |
ATPase copper transporting beta |
decreases expression |
EXP |
Streptozocin results in decreased expression of ATP7B protein |
CTD |
PMID:24927960 |
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NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636
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G |
Avp |
arginine vasopressin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of AVP mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Axl |
Axl receptor tyrosine kinase |
increases expression |
EXP |
Streptozocin results in increased expression of AXL protein |
CTD |
PMID:12644472 |
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NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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G |
B2m |
beta-2 microglobulin |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of B2M protein diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of B2M protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of B2M protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein] Metformin inhibits the reaction [Streptozocin results in increased expression of B2M protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of B2M protein] |
CTD |
PMID:33639173 PMID:34649470 |
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NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
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G |
B3galnt1 |
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of B3GALNT1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:153,847,297...153,877,371
Ensembl chr 2:153,846,474...153,877,332
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G |
Baat |
bile acid CoA:amino acid N-acyltransferase |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of BAAT mRNA |
CTD |
PMID:29382564 |
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NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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G |
Bace1 |
beta-secretase 1 |
multiple interactions increases expression |
ISO |
Alendronate inhibits the reaction [Streptozocin results in increased expression of BACE1 protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of BACE1 protein] |
CTD |
PMID:30481507 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Bad |
BCL2-associated agonist of cell death |
multiple interactions decreases expression increases expression |
EXP |
Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BAD protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of BAD protein Streptozocin results in decreased expression of BAD protein; Streptozocin results in decreased expression of BAD protein modified form |
CTD |
PMID:15976052 PMID:19682444 PMID:28856781 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions increases expression |
EXP |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] |
CTD |
PMID:28856781 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression affects expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of BAX protein]; phillyrin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of BAX protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of BAX protein] Streptozocin results in increased expression of BAX; Streptozocin results in increased expression of BAX mRNA; Streptozocin results in increased expression of BAX protein 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of BAX protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein; [Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BAX protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of BAX protein]; ferulic acid inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of BAX protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BAX protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of BAX]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of BAX protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of BAX protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]]]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of BAX protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of BAX protein] |
CTD |
PMID:11375343 PMID:18758938 PMID:19931367 PMID:20574430 PMID:20650802 PMID:22429817 PMID:23267840 PMID:24954035 PMID:24967692 PMID:25191525 PMID:25301743 PMID:25541178 PMID:27702591 PMID:29266779 PMID:29953732 PMID:30611788 PMID:30980806 PMID:31009641 PMID:31029786 PMID:31323227 PMID:32805344 PMID:33484791 PMID:33724628 PMID:34455488 PMID:34610774 PMID:34649470 PMID:35414346 PMID:36510688 PMID:37431890 More...
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Baz1b |
bromodomain adjacent to zinc finger domain, 1B |
affects expression |
ISO |
Streptozocin affects the expression of BAZ1B mRNA |
CTD |
PMID:26073000 |
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NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
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G |
Bbox1 |
gamma-butyrobetaine hydroxylase 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of BBOX1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458
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G |
Bche |
butyrylcholinesterase |
multiple interactions increases activity |
ISO |
Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein] |
CTD |
PMID:27087133 PMID:30481507 |
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NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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G |
Bckdha |
branched chain keto acid dehydrogenase E1 subunit alpha |
affects expression |
ISO |
Streptozocin affects the expression of BCKDHA mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:81,138,946...81,167,765
Ensembl chr 1:81,138,947...81,167,862
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression decreases expression multiple interactions affects expression |
EXP ISO |
Streptozocin results in increased expression of BCL2 protein Streptozocin results in decreased expression of BCL2 mRNA; Streptozocin results in decreased expression of BCL2 protein [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of BCL2 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of BCL2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisphenol A promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Ethinyl Estradiol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; montelukast inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; octylphenol promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; phillyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BCL2 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of BCL2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; [Streptozocin co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Lead] results in decreased expression of BCL2 mRNA; [Streptozocin co-treated with Manganese] results in decreased expression of BCL2 mRNA; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Curcumin inhibits the reaction [Streptozocin affects the expression of BCL2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Diazoxide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of BCL2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2 mRNA]; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of BCL2 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Propofol inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in decreased expression of BCL2 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Testosterone promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Sildenafil Citrate promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Testosterone promotes the reaction [Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]; Testosterone promotes the reaction [Tadalafil promotes the reaction [Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]]]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 mRNA]; Zinc inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] |
CTD |
PMID:15056984 PMID:15587404 PMID:15976052 PMID:16909474 PMID:18758938 PMID:19682444 PMID:20574430 PMID:20650802 PMID:22429817 PMID:24781736 PMID:24810525 PMID:24954035 PMID:25301743 PMID:25541178 PMID:25665769 PMID:26967640 PMID:27702591 PMID:28856781 PMID:29266779 PMID:29953732 PMID:30607903 PMID:30611788 PMID:31009641 PMID:31323227 PMID:32246071 PMID:32805344 PMID:33484791 PMID:33724628 PMID:34455488 PMID:34610774 PMID:34649470 PMID:35414346 PMID:36462176 PMID:36510688 PMID:37352119 PMID:37431890 More...
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of BCL2A1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
increases expression multiple interactions decreases expression |
EXP ISO |
Streptozocin results in increased expression of BCL2L1 protein Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of BCL2L1 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BCL2L1 mRNA]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein]] Streptozocin results in decreased expression of BCL2L1 mRNA; Streptozocin results in decreased expression of BCL2L1 protein |
CTD |
PMID:15976052 PMID:16595661 PMID:18758938 PMID:19682444 PMID:24781736 PMID:28856781 PMID:35414346 More...
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of BCL2L11 mRNA Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of BCL2L11 mRNA] |
CTD |
PMID:33524429 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bcl3 |
BCL3, transcription coactivator |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of BCL3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:79,471,368...79,485,908
Ensembl chr 1:79,471,369...79,485,607
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G |
Bdh1 |
3-hydroxybutyrate dehydrogenase 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of BDH1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
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G |
Bdkrb1 |
bradykinin receptor B1 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of BDKRB1 mRNA [HOE 140, desArg(10)- binds to and results in decreased activity of BDKRB1 protein] which results in decreased susceptibility to Streptozocin |
CTD |
PMID:17989505 PMID:19516248 |
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NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Bdkrb2 |
bradykinin receptor B2 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of BDKRB2 mRNA [icatibant binds to and results in decreased activity of BDKRB2 protein] which results in decreased susceptibility to Streptozocin |
CTD |
PMID:17989505 PMID:19516248 |
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NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497
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G |
Bdnf |
brain-derived neurotrophic factor |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of BDNF mRNA; Streptozocin results in decreased expression of BDNF protein Metformin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of BDNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]] 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BDNF protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BDNF protein] |
CTD |
PMID:32805344 PMID:34428446 PMID:35414346 PMID:38049026 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Becn1 |
beclin 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Streptozocin results in increased expression of BECN1 mRNA; Streptozocin results in increased expression of BECN1 protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form]; HU 308 inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of BECN1 protein modified form] Streptozocin results in decreased expression of BECN1 protein; Streptozocin results in decreased expression of BECN1 protein modified form [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of BECN1 mRNA; dapagliflozin affects the reaction [Streptozocin results in decreased expression of BECN1 mRNA] |
CTD |
PMID:24889822 PMID:30459625 PMID:34428446 PMID:35786680 PMID:37352119 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bglap |
bone gamma-carboxyglutamate protein |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of BGLAP mRNA; Streptozocin results in decreased expression of BGLAP protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of BGLAP protein modified form] [Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein; Calcitriol inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of BGLAP protein] |
CTD |
PMID:25617479 PMID:27488359 PMID:33450223 |
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NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
increases activity increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased activity of BHMT protein Streptozocin results in increased expression of BHMT mRNA [Streptozocin co-treated with Dietary Fats] affects the expression of BHMT mRNA |
CTD |
PMID:16835399 PMID:29127188 |
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NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Bmal1 |
basic helix-loop-helix ARNT like 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of BMAL1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
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G |
Bmp6 |
bone morphogenetic protein 6 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of BMP6 mRNA esculetin inhibits the reaction [Streptozocin results in decreased expression of BMP6 mRNA] |
CTD |
PMID:21450970 |
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NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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G |
Bmp7 |
bone morphogenetic protein 7 |
increases expression affects expression |
EXP |
Streptozocin results in increased expression of BMP7 protein Streptozocin affects the expression of BMP7 mRNA |
CTD |
PMID:17437042 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
C1qa |
complement C1q A chain |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of C1QA mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
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G |
C1qb |
complement C1q B chain |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of C1QB mRNA [resveratrol co-treated with Streptozocin] results in increased expression of C1QB mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C1QB mRNA] |
CTD |
PMID:16684804 PMID:25905778 |
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NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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G |
C1qc |
complement C1q C chain |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of C1QC mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:149,127,412...149,130,757
Ensembl chr 5:149,127,415...149,131,017
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G |
C4b |
complement C4B |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of C4B mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of C4B mRNA] |
CTD |
PMID:16684804 |
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NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
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G |
Cacna1b |
calcium voltage-gated channel subunit alpha1 B |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1B mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 3:7,380,892...7,546,104
Ensembl chr 3:7,380,922...7,546,091
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G |
Cacna1c |
calcium voltage-gated channel subunit alpha1 C |
multiple interactions increases expression |
ISO |
[bisphenol A co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA; [octylphenol co-treated with Streptozocin] results in decreased expression of CACNA1C mRNA Streptozocin results in increased expression of CACNA1C mRNA |
CTD |
PMID:29935216 |
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NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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G |
Cacna1s |
calcium voltage-gated channel subunit alpha1 S |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CACNA1S mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
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G |
Calca |
calcitonin-related polypeptide alpha |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CALCA protein Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of CALCA protein] |
CTD |
PMID:30583000 |
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NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G |
Calm1 |
calmodulin 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of CALM1 protein] |
CTD |
PMID:32303808 |
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NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227
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G |
Calm3 |
calmodulin 3 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CALM3 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CALM3 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207
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G |
Calr |
calreticulin |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CALR protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CALR protein] |
CTD |
PMID:19634143 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Camk2a |
calcium/calmodulin-dependent protein kinase II alpha |
multiple interactions decreases expression |
ISO EXP |
myristoylated autocamtide-2-related inhibitory peptide inhibits the reaction [Streptozocin results in increased phosphorylation of CAMK2A protein]; resveratrol inhibits the reaction [Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein]; Streptozocin results in increased expression of and results in increased phosphorylation of and results in increased activity of CAMK2A protein Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of CAMK2A protein] Streptozocin results in decreased expression of CAMK2A mRNA; Streptozocin results in decreased expression of CAMK2A protein |
CTD |
PMID:20424226 PMID:24333387 |
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NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994
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G |
Camp |
cathelicidin antimicrobial peptide |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CAMP mRNA |
CTD |
PMID:33484791 |
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NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543
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G |
Canx |
calnexin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of CANX protein] |
CTD |
PMID:34801538 |
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NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821
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G |
Capg |
capping actin protein, gelsolin like |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CAPG mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
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G |
Capn8 |
calpain 8 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CAPN8 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:94,252,218...94,316,146
Ensembl chr13:94,253,054...94,316,146
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G |
Car3 |
carbonic anhydrase 3 |
multiple interactions decreases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of CAR3 mRNA Streptozocin results in decreased expression of CAR3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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G |
Cartpt |
CART prepropeptide |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CARTPT mRNA GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713
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G |
Casp1 |
caspase 1 |
multiple interactions increases expression |
EXP ISO |
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased cleavage of CASP1 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of CASP1 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of CASP1 mRNA]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein Streptozocin results in increased expression of CASP1 mRNA; Streptozocin results in increased expression of CASP1 protein [aucubin co-treated with Streptozocin co-treated with Dietary Fats] results in decreased cleavage of CASP1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased cleavage of CASP1 protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CASP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP1 protein |
CTD |
PMID:23647015 PMID:26614261 PMID:27783111 PMID:32202043 PMID:34212273 PMID:34964214 PMID:35961541 PMID:36999408 PMID:37081038 PMID:37473909 More...
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NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp12 |
caspase 12 |
increases expression increases cleavage multiple interactions |
ISO EXP |
Streptozocin results in increased expression of CASP12 protein modified form Streptozocin results in increased cleavage of CASP12 protein FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP12 protein] |
CTD |
PMID:23499715 PMID:24967692 PMID:25541178 |
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NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity decreases cleavage increases cleavage increases expression decreases expression |
EXP ISO |
3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein; [Rolipram co-treated with Pentoxifylline] inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; [Streptozocin co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with Lead co-treated with Manganese co-treated with Cadmium co-treated with Arsenic] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Lead] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Manganese] results in increased expression of CASP3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased cleavage of CASP3 protein]; Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ellagic Acid promotes the reaction [sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; ferulic acid analog inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP3 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Imatinib Mesylate inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]]; Memantine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP3 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; Propofol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Rolipram inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; sinapinic acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; sinapinic acid promotes the reaction [Ellagic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]]; Streptozocin results in increased expression of and results in increased cleavage of CASP3 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] Streptozocin analog results in increased activity of CASP3 protein; Streptozocin results in increased activity of CASP3 protein [Streptozocin co-treated with bisphenol A] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] affects the cleavage of CASP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with octylphenol] results in increased expression of CASP3 mRNA; fatostatin promotes the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Metformin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of CASP3 protein modified form]; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; phillyrin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Cisplatin results in increased expression of CASP3 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of CASP3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein; Streptozocin results in increased expression of CASP3 protein modified form Streptozocin results in increased expression of CASP3 mRNA; Streptozocin results in increased expression of CASP3 protein modified form Streptozocin results in decreased expression of CASP3 mRNA; Streptozocin results in decreased expression of CASP3 protein |
CTD |
PMID:12502508 PMID:15976052 PMID:18721751 PMID:18758938 PMID:19133311 PMID:19682444 PMID:19840221 PMID:19931367 PMID:19951573 PMID:20053369 PMID:20224876 PMID:20424226 PMID:20654064 PMID:21599458 PMID:23267840 PMID:23453443 PMID:23458895 PMID:24333387 PMID:24810525 PMID:24967692 PMID:25541178 PMID:25665769 PMID:26499206 PMID:26614261 PMID:26887929 PMID:27702591 PMID:28856781 PMID:29059224 PMID:29420703 PMID:29606028 PMID:29935216 PMID:30980806 PMID:31029786 PMID:31323227 PMID:32246071 PMID:32710900 PMID:32805344 PMID:33484791 PMID:34455488 PMID:34610774 PMID:34649470 PMID:34661493 PMID:35414346 PMID:36462176 PMID:36504472 PMID:36510688 PMID:37081038 PMID:37352119 PMID:37431890 PMID:38049026 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp4 |
caspase 4 |
increases expression |
ISO |
Streptozocin results in increased expression of CASP4 mRNA |
CTD |
PMID:34212273 |
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NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
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G |
Casp6 |
caspase 6 |
increases expression |
EXP |
Streptozocin results in increased expression of CASP6 protein |
CTD |
PMID:15976052 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp7 |
caspase 7 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CASP7 protein [Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CASP7 protein]] |
CTD |
PMID:15976052 PMID:30551545 |
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NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions increases expression increases cleavage increases activity |
EXP |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of CASP8 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP8 protein] Streptozocin results in increased expression of CASP8 mRNA; Streptozocin results in increased expression of CASP8 protein |
CTD |
PMID:23267840 PMID:25541178 PMID:28856781 PMID:29606028 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases expression increases activity decreases expression |
EXP ISO |
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of CASP9 protein]; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]]; nifuroxazide inhibits the reaction [Streptozocin results in increased activity of CASP9 protein]; Ozone inhibits the reaction [Streptozocin results in increased expression of CASP9 mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased expression of CASP9 protein]; Streptozocin results in increased expression of and results in increased cleavage of CASP9 protein; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of CASP9 protein] Streptozocin results in increased expression of CASP9 mRNA; Streptozocin results in increased expression of CASP9 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CASP9 protein] |
CTD |
PMID:15976052 PMID:19951573 PMID:22940631 PMID:26614261 PMID:28856781 PMID:29606028 PMID:34455488 PMID:34610774 PMID:36462176 PMID:36510688 More...
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
increases expression multiple interactions decreases response to substance increases phosphorylation decreases expression increases activity decreases activity |
ISO EXP |
Streptozocin results in increased expression of CAT mRNA Streptozocin results in increased expression of CAT protein CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin] Streptozocin results in increased phosphorylation of CAT protein Streptozocin results in decreased expression of CAT; Streptozocin results in decreased expression of CAT mRNA 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT mRNA; [Streptozocin co-treated with Dextran Sulfate] results in decreased expression of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; Acrylamide promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Alendronate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Donepezil inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of CAT]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of CAT protein] Streptozocin results in decreased expression of CAT mRNA; Streptozocin results in decreased expression of CAT protein 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]]; 2-hydroxy-4-methoxy benzoic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in increased expression of CAT protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; 5,3'-dihydroxy-3,6,7,4',5'-pentamethoxyflavone inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CAT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Fructose co-treated with Streptozocin] results in decreased activity of CAT protein; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; [Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of CAT protein; [Propolis co-treated with Streptozocin] results in increased activity of CAT protein; [Quercetin co-treated with coenzyme Q10] inhibits the reaction [Streptozocin results in increased activity of CAT protein]; [Quercetin co-treated with Streptozocin] results in increased activity of CAT protein; [Rosiglitazone co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of CAT protein; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein; [Streptozocin co-treated with Isoproterenol] affects the activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; alpha-Tocopherol inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased activity of CAT protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; corilagin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Diltiazem inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Diosmin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Gallic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Imipramine inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; isoquercitrin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Losartan inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; mangiferin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Melatonin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; morin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; myrsinoic acid B inhibits the reaction [Streptozocin results in increased activity of CAT protein]; myrtenol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; naringenin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of CAT protein]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; palbinone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; pinitol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of CAT protein]; Propolis inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Streptozocin results in increased activity of CAT protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of CAT protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAT mRNA]; Resveratrol promotes the reaction [Streptozocin results in decreased expression of CAT mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the activity of CAT protein]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; Saponins inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; sodium arsenate promotes the reaction [Streptozocin results in decreased activity of CAT protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Streptozocin inhibits the reaction [Lipopolysaccharides results in increased expression of CAT protein]; Streptozocin inhibits the reaction [Streptozocin results in increased expression of CAT protein]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of CAT protein]; Streptozocin results in decreased expression of and results in decreased activity of CAT protein; Streptozocin results in increased expression of and results in increased activity of CAT protein; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Tocotrienols inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; U 78517F inhibits the reaction [Streptozocin results in decreased expression of CAT protein]; vanillin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased activity of CAT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of CAT protein] |
CTD |
PMID:9522273 PMID:11424224 PMID:12123627 PMID:12242689 PMID:15298345 PMID:15821039 PMID:15855331 PMID:15957552 PMID:16177186 PMID:16581090 PMID:16780994 PMID:17042909 PMID:17145126 PMID:18779489 PMID:19133311 PMID:19464315 PMID:19682444 PMID:19840221 PMID:19931367 PMID:20053369 PMID:20307516 PMID:20643114 PMID:20691780 PMID:20828602 PMID:20951120 PMID:21382363 PMID:21439372 PMID:21457706 PMID:21630391 PMID:22056647 PMID:22476978 PMID:22733486 PMID:23122718 PMID:23677724 PMID:23716880 PMID:24740756 PMID:24752916 PMID:24760747 PMID:24854284 PMID:24877639 PMID:24954035 PMID:24967692 PMID:25057273 PMID:25362599 PMID:25503068 PMID:25617480 PMID:25986969 PMID:26286521 PMID:26286522 PMID:26341651 PMID:26499206 PMID:26690102 PMID:26700463 PMID:26748309 PMID:27350165 PMID:28178614 PMID:28757134 PMID:29223569 PMID:29233026 PMID:29247773 PMID:29274332 PMID:29331653 PMID:29409856 PMID:29441829 PMID:29988851 PMID:30144451 PMID:30318971 PMID:30481507 PMID:30582900 PMID:30817903 PMID:30847815 PMID:30958922 PMID:31009641 PMID:31100278 PMID:31400774 PMID:31682803 PMID:32202043 PMID:32662907 PMID:32710900 PMID:32812462 PMID:32864810 PMID:33359794 PMID:33639173 PMID:33724628 PMID:33823243 PMID:34039237 PMID:34352274 PMID:34477272 PMID:34610774 PMID:34896238 PMID:34922902 PMID:34964214 PMID:35187753 PMID:35414346 PMID:35961541 PMID:36169646 PMID:36510688 PMID:36999408 PMID:37120126 PMID:37352119 PMID:37354076 PMID:37482253 PMID:37566541 PMID:38602238 More...
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
multiple interactions increases expression |
EXP |
resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; resveratrol inhibits the reaction [Streptozocin results in increased expression of CAV1 protein]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein] |
CTD |
PMID:18266981 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cav3 |
caveolin 3 |
multiple interactions decreases expression |
EXP |
resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of CAV3 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein] |
CTD |
PMID:18266981 |
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NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
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G |
Cbr1 |
carbonyl reductase 1 |
decreases activity |
EXP |
Streptozocin results in decreased activity of CBR1 protein |
CTD |
PMID:11057757 |
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NCBI chr11:32,860,571...32,862,981
Ensembl chr11:32,908,950...32,911,393 Ensembl chr11:32,908,950...32,911,393
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G |
Cbs |
cystathionine beta synthase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CBS mRNA |
CTD |
PMID:29127188 |
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NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
affects response to substance increases expression multiple interactions increases secretion |
ISO EXP |
CCL2 affects the susceptibility to Streptozocin Streptozocin results in increased expression of CCL2; Streptozocin results in increased expression of CCL2 mRNA; Streptozocin results in increased expression of CCL2 protein [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of CCL2 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of CCL2 protein]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; prolinedithiocarbamate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Streptozocin results in increased expression of and results in increased secretion of CCL2 protein; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA] 4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein; [fatostatin co-treated with Streptozocin] results in increased expression of CCL2 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCL2 mRNA]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein]]; Valsartan inhibits the reaction [Streptozocin results in increased expression of CCL2 protein] |
CTD |
PMID:15284299 PMID:16374426 PMID:16684804 PMID:17624267 PMID:18413206 PMID:18999900 PMID:19921414 PMID:21832210 PMID:23611540 PMID:24513509 PMID:25199697 PMID:27664441 PMID:27769711 PMID:29266779 PMID:29420703 PMID:29988851 PMID:30184259 PMID:30551545 PMID:31696645 PMID:33639173 PMID:37482253 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CCL3 mRNA AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CCL3 mRNA]] |
CTD |
PMID:30184259 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression |
ISO |
Streptozocin results in increased expression of CCL5 mRNA |
CTD |
PMID:29420703 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
multiple interactions |
EXP |
[Resveratrol co-treated with Streptozocin] results in increased expression of CCL6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of CCN2; Streptozocin results in increased expression of CCN2 protein [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] [Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CCN2 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] Streptozocin results in increased expression of CCN2 mRNA; Streptozocin results in increased expression of CCN2 protein |
CTD |
PMID:10026205 PMID:14586741 PMID:17270171 PMID:19369054 PMID:19657322 PMID:19895808 PMID:21416479 PMID:24707343 PMID:24967692 PMID:25057273 PMID:28648635 PMID:31062909 PMID:34175429 PMID:34310909 More...
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CCND1 mRNA 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of CCND1 mRNA] |
CTD |
PMID:34428446 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccnd2 |
cyclin D2 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CCND2 protein AM 251 inhibits the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein] |
CTD |
PMID:26967640 |
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NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
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G |
Ccnt1 |
cyclin T1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CCNT1 protein] |
CTD |
PMID:20828602 |
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NCBI chr 7:129,687,146...129,718,080
Ensembl chr 7:129,691,209...129,717,871
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CCR2 mRNA [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CCR2 mRNA] |
CTD |
PMID:30184259 |
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NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccs |
copper chaperone for superoxide dismutase |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CCS mRNA; Streptozocin results in decreased expression of CCS protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of CCS protein] |
CTD |
PMID:24927960 |
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NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915
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G |
Cd14 |
CD14 molecule |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CD14 mRNA |
CTD |
PMID:29127188 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd163 |
CD163 molecule |
multiple interactions decreases expression |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CD163 mRNA Streptozocin results in decreased expression of CD163 mRNA AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of CD163 mRNA]] |
CTD |
PMID:25905778 PMID:30184259 |
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NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
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G |
Cd200r1l |
CD200 receptor 1-like |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CD200R1L mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:55,842,632...55,860,914
Ensembl chr11:55,842,634...55,885,680
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G |
Cd24 |
CD24 molecule |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CD24A mRNA |
CTD |
PMID:29127188 |
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NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CD36 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CD36 mRNA] |
CTD |
PMID:29127188 PMID:34896238 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd53 |
Cd53 molecule |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CD53 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657
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G |
Cd5l |
Cd5 molecule-like |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CD5L mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753
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G |
Cd68 |
Cd68 molecule |
multiple interactions increases expression |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CD68 mRNA; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of CD68 protein] Streptozocin results in increased expression of CD68 mRNA AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of CD68 mRNA]] |
CTD |
PMID:25905778 PMID:29291386 PMID:30184259 |
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NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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G |
Cd80 |
Cd80 molecule |
multiple interactions increases expression |
ISO |
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD80 protein] |
CTD |
PMID:15892581 |
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NCBI chr11:62,254,543...62,293,414
Ensembl chr11:62,254,624...62,292,030
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G |
Cd86 |
CD86 molecule |
multiple interactions increases expression |
ISO EXP |
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of CD86 protein] [resveratrol co-treated with Streptozocin] results in increased expression of CD86 mRNA |
CTD |
PMID:15892581 PMID:25905778 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cdca2 |
cell division cycle associated 2 |
multiple interactions |
ISO |
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of CDCA2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CDCA2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
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G |
Cdh1 |
cadherin 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of CDH1 |
CTD |
PMID:32469605 |
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh2 |
cadherin 2 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CDH2 protein rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CDH2 protein] |
CTD |
PMID:31682803 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdk15 |
cyclin-dependent kinase 15 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDK15 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 9:60,710,787...60,803,638
Ensembl chr 9:60,711,715...60,802,777
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G |
Cdk9 |
cyclin-dependent kinase 9 |
multiple interactions increases phosphorylation |
EXP ISO |
[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA; [Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Berberine affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; Fenofibrate affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 mRNA]; rosiglitazone affects the reaction [[Streptozocin co-treated with Dietary Carbohydrates co-treated with Dietary Fats] affects the expression of CDK9 protein] Streptozocin results in increased phosphorylation of CDK9 protein |
CTD |
PMID:20828602 PMID:33631230 |
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NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO EXP |
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of CDKN1A mRNA; Quercetin inhibits the reaction [Streptozocin results in increased expression of CDKN1A mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A] Streptozocin results in increased expression of CDKN1A; Streptozocin results in increased expression of CDKN1A mRNA Streptozocin results in increased expression of CDKN1A mRNA; Streptozocin results in increased expression of CDKN1A protein Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of CDKN1A protein]; Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] |
CTD |
PMID:19496084 PMID:22744176 PMID:25301743 PMID:27652271 PMID:29127188 PMID:29673160 PMID:38483099 More...
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn2a |
cyclin-dependent kinase inhibitor 2A |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CDKN2A mRNA; Streptozocin results in increased expression of CDKN2A protein 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of CDKN2A protein; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein] |
CTD |
PMID:29059224 PMID:29673160 PMID:38483099 |
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NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
multiple interactions decreases expression |
ISO |
CEBPB protein affects the reaction [Streptozocin results in increased expression of AGT protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of AGT protein modified form]; CEBPB protein inhibits the reaction [Streptozocin results in decreased abundance of angiotensin I (1-7)]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of ACE protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR1 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of AGTR2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of CCL2 protein]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein] Streptozocin results in decreased expression of CEBPB protein |
CTD |
PMID:29266779 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cebpd |
CCAAT/enhancer binding protein delta |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CEBPD mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
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G |
Celf2 |
CUGBP, Elav-like family member 2 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CELF2 protein |
CTD |
PMID:38282657 |
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NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333
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G |
Celf4 |
CUGBP, Elav-like family member 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CELF4 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr18:16,786,578...17,065,045
Ensembl chr18:16,786,867...17,064,786
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G |
Ces2c |
carboxylesterase 2C |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CES2C mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
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G |
Ces4a |
carboxylesterase 4A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CES4A mRNA |
CTD |
PMID:33484791 |
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NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545
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G |
Cfap45 |
cilia and flagella associated protein 45 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CFAP45 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr13:84,989,474...85,012,880
Ensembl chr13:84,981,728...85,012,878
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G |
Cfap69 |
cilia and flagella associated protein 69 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CFAP69 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:28,379,604...28,452,562
Ensembl chr 4:28,375,996...28,450,698
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G |
Cfd |
complement factor D |
increases expression |
EXP |
Streptozocin results in increased expression of CFD mRNA |
CTD |
PMID:3299706 |
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NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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G |
Cfl1 |
cofilin 1 |
multiple interactions increases phosphorylation |
EXP |
fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of CFL1 protein] |
CTD |
PMID:22062134 |
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NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Cfp |
complement factor properdin |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CFP mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573
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G |
Chat |
choline O-acetyltransferase |
multiple interactions affects localization decreases expression |
EXP |
Inositol inhibits the reaction [Streptozocin affects the localization of CHAT protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of CHAT protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of CHAT protein] |
CTD |
PMID:2431858 PMID:32805344 |
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NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093
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G |
Chga |
chromogranin A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CHGA mRNA |
CTD |
PMID:33484791 |
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NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
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G |
Chka |
choline kinase alpha |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CHKA mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
multiple interactions affects expression increases expression |
EXP |
1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 mRNA]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of CHRM2 protein] Streptozocin results in increased expression of CHRM2 mRNA; Streptozocin results in increased expression of CHRM2 protein |
CTD |
PMID:17989502 PMID:18715473 |
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NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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G |
Chrm3 |
cholinergic receptor, muscarinic 3 |
multiple interactions affects expression |
EXP |
1-hexacosanol inhibits the reaction [Streptozocin affects the expression of CHRM3 mRNA] |
CTD |
PMID:17989502 |
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NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278
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G |
Chrna4 |
cholinergic receptor nicotinic alpha 4 subunit |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CHRNA4 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957
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G |
Chst8 |
carbohydrate sulfotransferase 8 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of CHST8 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:87,294,144...87,435,900
Ensembl chr 1:87,294,540...87,435,900
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions increases expression |
EXP |
Quercetin inhibits the reaction [Streptozocin results in increased expression of CHUK protein] |
CTD |
PMID:16177186 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Cidea |
cell death-inducing DFFA-like effector a |
multiple interactions |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of CIDEA mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of CIDEA mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
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G |
Cisd1 |
CDGSH iron sulfur domain 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CISD1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of CISD1 protein] |
CTD |
PMID:19634143 |
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NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
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G |
Cited2 |
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
increases expression multiple interactions decreases expression |
EXP ISO |
Streptozocin results in increased expression of CITED2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CITED2 mRNA] SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA] |
CTD |
PMID:16684804 PMID:27629361 |
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NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897
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G |
Ckmt2 |
creatine kinase, mitochondrial 2 |
multiple interactions decreases expression |
EXP |
vanadyl sulfate inhibits the reaction [Streptozocin results in decreased expression of CKMT2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430
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G |
Cldn1 |
claudin 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of CLDN1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn11 |
claudin 11 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of CLDN11 protein rhodioloside inhibits the reaction [Streptozocin results in decreased expression of CLDN11 protein] |
CTD |
PMID:31682803 |
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NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050
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G |
Cldn2 |
claudin 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of CLDN2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:103,459,870...103,473,794
Ensembl chr X:103,459,780...103,474,838
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G |
Clec4d |
C-type lectin domain family 4, member D |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CLEC4D mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848
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G |
Clec4f |
C-type lectin domain family 4, member F |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CLEC4F mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775
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G |
Clic4 |
chloride intracellular channel 4 |
affects expression |
ISO |
Streptozocin affects the expression of CLIC4 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452
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G |
Clpp |
caseinolytic mitochondrial matrix peptidase proteolytic subunit |
affects expression |
ISO |
Streptozocin affects the expression of CLPP mRNA |
CTD |
PMID:18583417 |
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NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
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G |
Clu |
clusterin |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CLU protein Trientine inhibits the reaction [Streptozocin results in increased expression of CLU protein] |
CTD |
PMID:19634143 |
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NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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G |
Cnpy1 |
canopy FGF signaling regulator 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CNPY1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 4:7,182,311...7,191,408
Ensembl chr 4:7,136,533...7,189,761
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions increases expression decreases expression |
EXP ISO |
[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of CNR1 mRNA] Streptozocin results in increased expression of CNR1 mRNA; Streptozocin results in increased expression of CNR1 protein [Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein; [Streptozocin co-treated with CNR1 protein] affects the phosphorylation of AKT1 protein; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of CCND2 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein] Streptozocin results in decreased expression of CNR1 protein |
CTD |
PMID:26967640 PMID:30184259 PMID:30642005 PMID:30721768 PMID:31468622 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of COL1A1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of COL1A1 mRNA] |
CTD |
PMID:28700904 PMID:29988851 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col3a1 |
collagen type III alpha 1 chain |
multiple interactions increases expression |
EXP ISO |
INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein] Valsartan inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein] |
CTD |
PMID:29266779 PMID:29682576 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col4a1 |
collagen type IV alpha 1 chain |
decreases expression increases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of COL4A1 mRNA Streptozocin results in increased expression of COL4A1 mRNA benazepril inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter] [fatostatin co-treated with Streptozocin] results in increased expression of COL4A1 mRNA |
CTD |
PMID:11798618 PMID:15496156 PMID:17582205 PMID:27997345 PMID:29420703 |
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NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
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G |
Col4a2 |
collagen type IV alpha 2 chain |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of COL4A2 mRNA MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA] |
CTD |
PMID:30642005 |
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NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
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G |
Col4a3 |
collagen type IV alpha 3 chain |
multiple interactions increases expression |
EXP |
Zinc inhibits the reaction [Streptozocin results in increased expression of COL4A3 mRNA] |
CTD |
PMID:31009641 |
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NCBI chr 9:83,875,849...84,004,955
Ensembl chr 9:83,875,561...84,001,895
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G |
Col4a4 |
collagen type IV alpha 4 chain |
multiple interactions increases expression |
ISO |
3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of COL4A4 mRNA] |
CTD |
PMID:33631230 |
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NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876
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G |
Col6a1 |
collagen type VI alpha 1 chain |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of COL6A1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A1 protein] |
CTD |
PMID:19634143 |
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NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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G |
Col6a2 |
collagen type VI alpha 2 chain |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of COL6A2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A2 protein] |
CTD |
PMID:19634143 |
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NCBI chr20:12,021,676...12,049,425
Ensembl chr20:12,021,767...12,057,564
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G |
Col6a3 |
collagen type VI alpha 3 chain |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of COL6A3 protein Trientine inhibits the reaction [Streptozocin results in increased expression of COL6A3 protein] |
CTD |
PMID:19634143 |
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NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471
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G |
Col7a1 |
collagen type VII alpha 1 chain |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of COL7A1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 8:109,604,877...109,637,249
Ensembl chr 8:109,604,861...109,637,252
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G |
Cotl1 |
coactosin-like F-actin binding protein 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of COTL1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:47,871,689...47,906,010
Ensembl chr19:47,871,694...47,911,689
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G |
Cox17 |
cytochrome c oxidase copper chaperone COX17 |
affects expression |
ISO |
Streptozocin affects the expression of COX17 mRNA |
CTD |
PMID:18583417 |
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NCBI chr11:62,400,733...62,406,507
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G |
Cox5b |
cytochrome c oxidase subunit 5B |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of COX5B mRNA] |
CTD |
PMID:37337224 |
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NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
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G |
Cp |
ceruloplasmin |
multiple interactions decreases expression |
EXP |
caryophyllene inhibits the reaction [Streptozocin results in decreased expression of CP protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of CP protein] |
CTD |
PMID:26748309 |
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NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Cpeb2 |
cytoplasmic polyadenylation element binding protein 2 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB2 protein] |
CTD |
PMID:38282657 |
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NCBI chr14:67,787,503...67,839,973
Ensembl chr14:67,787,507...67,840,743
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G |
Cpeb4 |
cytoplasmic polyadenylation element binding protein 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of CPEB4 protein |
CTD |
PMID:38282657 |
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NCBI chr10:15,717,794...15,780,482
Ensembl chr10:15,717,794...15,780,603
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of CPT1A mRNA [resveratrol co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CPT1A mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CPT1A mRNA] |
CTD |
PMID:16684804 PMID:25905778 PMID:29988851 PMID:34896238 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CPT2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of CPT2 protein] |
CTD |
PMID:21136691 |
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NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions decreases phosphorylation |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CREB1 mRNA; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of CREB1 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein] |
CTD |
PMID:20665664 PMID:23562514 PMID:27292126 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crebbp |
CREB binding protein |
decreases expression |
EXP |
Streptozocin results in decreased expression of CREBBP mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crot |
carnitine O-octanoyltransferase |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CROT mRNA [resveratrol co-treated with Streptozocin] results in decreased expression of CROT mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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G |
Crp |
C-reactive protein |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRP protein] |
CTD |
PMID:33484791 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cry1 |
cryptochrome circadian regulator 1 |
increases expression |
EXP |
Streptozocin results in increased expression of CRY1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
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G |
Crybb3 |
crystallin, beta B3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CRYBB3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr12:43,557,103...43,562,120
Ensembl chr12:43,557,103...43,562,120
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G |
Cryz |
crystallin zeta |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CRYZ protein Trientine inhibits the reaction [Streptozocin results in decreased expression of CRYZ protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:243,552,037...243,580,369
Ensembl chr 2:243,552,119...243,579,758
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CSF1R mRNA |
CTD |
PMID:25905778 |
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NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415
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G |
Csrp3 |
cysteine and glycine rich protein 3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CSRP3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CSRP3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
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G |
Cst3 |
cystatin C |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein; Glyburide inhibits the reaction [Streptozocin results in increased expression of CST3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of CST3 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of CST3 protein] |
CTD |
PMID:30551545 PMID:33387473 |
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NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
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G |
Cth |
cystathionine gamma-lyase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] affects the expression of CTH mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234
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G |
Ctnnb1 |
catenin beta 1 |
multiple interactions increases phosphorylation |
ISO |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased phosphorylation of CTNNB1 protein] |
CTD |
PMID:34428446 |
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NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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G |
Ctsd |
cathepsin D |
increases expression |
ISO |
Streptozocin results in increased expression of CTSD protein |
CTD |
PMID:28468961 |
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NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
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G |
Ctsk |
cathepsin K |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of CTSK mRNA; Streptozocin results in increased expression of CTSK protein formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of CTSK protein] |
CTD |
PMID:25617479 PMID:35315182 |
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NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550
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G |
Ctss |
cathepsin S |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CTSS mRNA [resveratrol co-treated with Streptozocin] results in increased expression of CTSS mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of CTSS mRNA] |
CTD |
PMID:16684804 PMID:25905778 |
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NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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G |
Cubn |
cubilin |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of CUBN protein] |
CTD |
PMID:35151640 |
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NCBI chr17:76,385,046...76,593,133
Ensembl chr17:76,385,060...76,593,231
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of CXCL1 protein]] |
CTD |
PMID:36547818 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
multiple interactions decreases expression |
ISO |
[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [[Streptozocin co-treated with Oxygen deficiency] results in decreased expression of CXCL12 mRNA] Streptozocin results in decreased expression of CXCL12 mRNA; Streptozocin results in decreased expression of CXCL12 protein |
CTD |
PMID:18227068 PMID:34310909 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcr4 |
C-X-C motif chemokine receptor 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCR4 protein |
CTD |
PMID:30421503 |
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NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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G |
Cyb561 |
cytochrome b-561 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYB561 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr10:90,878,052...90,888,734
Ensembl chr10:90,878,054...90,884,787
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions increases expression |
EXP |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of CYBA mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of CYBA protein; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of CYBA mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYBA protein; [Resveratrol co-treated with Streptozocin] results in increased expression of CYBA mRNA; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of CYBA mRNA] |
CTD |
PMID:12967931 PMID:16139267 PMID:25905778 PMID:35786680 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cybb |
cytochrome b-245 beta chain |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of CYBB mRNA; Streptozocin results in increased expression of CYBB protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; [fatostatin co-treated with Streptozocin] results in increased expression of CYBB mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NOX2 mRNA]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of CYBB protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CYBB protein] |
CTD |
PMID:19957251 PMID:21381899 PMID:29420703 PMID:35085591 PMID:37120126 |
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NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586
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G |
Cyc1 |
cytochrome c-1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CYC1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of CYC1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
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G |
Cycs |
cytochrome c, somatic |
affects localization multiple interactions increases expression |
EXP ISO |
Streptozocin affects the localization of CYCS protein arjunolic acid inhibits the reaction [Streptozocin affects the localization of CYCS protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of CYCS mRNA]; Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of CYCS protein]; Thioctic Acid inhibits the reaction [Streptozocin affects the localization of CYCS protein] Streptozocin results in increased expression of CYCS mRNA; Streptozocin results in increased expression of CYCS protein Metformin inhibits the reaction [Streptozocin affects the localization of CYCS protein]; phillyrin inhibits the reaction [Streptozocin affects the localization of CYCS protein] |
CTD |
PMID:19682444 PMID:19951573 PMID:34455488 PMID:34649470 PMID:35414346 PMID:36462176 More...
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp11b3 |
cytochrome P450, family 11, subfamily b, polypeptide 3 |
increases expression |
EXP |
Streptozocin results in increased expression of CYP11B2 mRNA; Streptozocin results in increased expression of CYP11B2 protein |
CTD |
PMID:16043663 |
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NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions increases expression |
ISO EXP |
Metformin promotes the reaction [Streptozocin results in increased expression of CYP1A1 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP1A1 mRNA] [resveratrol co-treated with Streptozocin] results in increased expression of CYP1A1 mRNA |
CTD |
PMID:22342832 PMID:25905778 PMID:29382564 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression increases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of CYP1A2 protein Streptozocin results in increased expression of CYP1A2 protein [resveratrol co-treated with Streptozocin] results in decreased expression of CYP1A2 mRNA; [Streptozocin results in increased expression of CYP1A2 protein] which results in increased metabolism of Diazinon Streptozocin results in decreased expression of CYP1A2 mRNA [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP1A2 mRNA |
CTD |
PMID:12700423 PMID:17442507 PMID:25905778 PMID:29127188 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Cyp2a1 |
cytochrome P450, family 2, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of CYP2A1 mRNA [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A22 mRNA |
CTD |
PMID:25905778 PMID:33484791 |
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NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
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G |
Cyp2a3 |
cytochrome P450, family 2, subfamily a, polypeptide 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CYP2A4 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of CYP2B1 mRNA [resveratrol co-treated with Streptozocin] results in increased expression of CYP2B1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2b2 |
cytochrome P450, family 2, subfamily b, polypeptide 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of CYP2B13 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of CYP2B10 mRNA Berberine inhibits the reaction [Streptozocin results in increased expression of CYP2B10 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of CYP2B10 mRNA] |
CTD |
PMID:22342832 PMID:29382564 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2c11 |
cytochrome P450, subfamily 2, polypeptide 11 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP2C11 protein |
CTD |
PMID:24815820 |
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NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
decreases expression increases expression multiple interactions |
ISO EXP |
Streptozocin results in decreased expression of CYP2E1 protein Streptozocin results in increased expression of CYP2E1 mRNA; Streptozocin results in increased expression of CYP2E1 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased activity of CYP2E1 protein |
CTD |
PMID:11752103 PMID:12700423 PMID:14693714 PMID:24815820 PMID:25905778 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp2j4 |
cytochrome P450, family 2, subfamily j, polypeptide 4 |
increases expression |
EXP |
Streptozocin results in increased expression of CYP2J4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CYP4A1 mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:24815820 PMID:25905778 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp4a2 |
cytochrome P450, family 4, subfamily a, polypeptide 2 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of CYP4A2 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of CYP4A2 mRNA; Trientine promotes the reaction [Streptozocin results in decreased expression of CYP4A2 protein] |
CTD |
PMID:19634143 PMID:24815820 |
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NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
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G |
Cyp4f1 |
cytochrome P450, family 4, subfamily f, polypeptide 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP4F14 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of CYP7A1 mRNA [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of CYP7A1 mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein] |
CTD |
PMID:10393316 PMID:29382564 PMID:31100278 PMID:34896238 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp7b1 |
cytochrome P450 family 7 subfamily B member 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7B1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:29127188 PMID:29382564 |
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NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
multiple interactions increases expression |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; Streptozocin inhibits the reaction [resveratrol results in increased expression of CYP8B1 mRNA] Streptozocin results in increased expression of CYP8B1 mRNA; Streptozocin results in increased expression of CYP8B1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP8B1 mRNA |
CTD |
PMID:10393316 PMID:25905778 PMID:29382564 |
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NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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G |
Cysltr1 |
cysteinyl leukotriene receptor 1 |
multiple interactions increases expression |
ISO |
montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of CYSLTR1 protein] Streptozocin results in increased expression of CYSLTR1 mRNA; Streptozocin results in increased expression of CYSLTR1 protein |
CTD |
PMID:27702591 |
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NCBI chr X:71,661,421...71,690,012
Ensembl chr X:71,663,821...71,690,121
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G |
Cyyr1 |
cysteine and tyrosine rich 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of CYYR1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:24,557,620...24,664,007
Ensembl chr11:24,515,316...24,663,961
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G |
Dao |
D-amino-acid oxidase |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of DAO protein Trientine inhibits the reaction [Streptozocin results in increased expression of DAO protein] |
CTD |
PMID:19634143 |
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NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741
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G |
Dapk1 |
death associated protein kinase 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of DAPK1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991
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G |
Dapl1 |
death associated protein-like 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DAPL1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:43,960,993...43,980,940
Ensembl chr 3:43,960,810...43,980,940
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G |
Dbn1 |
drebrin 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of DBN1 protein |
CTD |
PMID:23333261 |
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NCBI chr17:9,150,608...9,164,982
Ensembl chr17:9,150,659...9,164,984
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G |
Dbt |
dihydrolipoamide branched chain transacylase E2 |
affects expression |
ISO |
Streptozocin affects the expression of DBT mRNA |
CTD |
PMID:18583417 |
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NCBI chr 2:204,481,744...204,510,612
Ensembl chr 2:204,481,737...204,510,609
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G |
Dcc |
DCC netrin 1 receptor |
multiple interactions increases expression |
ISO |
NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein] Streptozocin results in increased expression of DCC mRNA; Streptozocin results in increased expression of DCC protein |
CTD |
PMID:29059224 |
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NCBI chr18:64,868,987...65,972,783
Ensembl chr18:64,873,898...65,972,740
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression multiple interactions increases expression |
ISO EXP |
Streptozocin results in increased expression of DDIT3; Streptozocin results in increased expression of DDIT3 mRNA; Streptozocin results in increased expression of DDIT3 protein [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA]; [Streptozocin co-treated with bisphenol A] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of DDIT3 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of DDIT3 protein; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Streptozocin promotes the reaction [bisphenol A results in increased expression of DDIT3 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein] 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DDIT3 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of DDIT3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of DDIT3 protein] streptozocin increases expression of Ddit3 protein in heart |
CTD RGD |
PMID:23499715 PMID:24967692 PMID:29935216 PMID:30980806 PMID:34801538 PMID:37054934 PMID:38049026 PMID:38282657 PMID:36044268 More...
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RGD:156430337 |
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Ddit4 |
DNA-damage-inducible transcript 4 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of DDIT4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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G |
Decr1 |
2,4-dienoyl-CoA reductase 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of DECR1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of DECR1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
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G |
Derl1 |
derlin 1 |
multiple interactions increases expression |
EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of DERL1 protein] |
CTD |
PMID:30980806 |
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NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145
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G |
Derl3 |
derlin 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of DERL3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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G |
Des |
desmin |
multiple interactions increases expression |
EXP |
Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of DES protein] |
CTD |
PMID:12197670 PMID:17624267 |
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NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA] |
CTD |
PMID:33812996 |
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NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of DGAT2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of DGAT2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of DGAT2 mRNA |
CTD |
PMID:35786680 |
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NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Dgkh |
diacylglycerol kinase, eta |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of DGKH mRNA |
CTD |
PMID:20665664 |
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NCBI chr15:53,981,079...54,150,470
Ensembl chr15:53,991,481...54,150,706
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G |
Dhrs7 |
dehydrogenase/reductase 7 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of DHRS7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892
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G |
Dhrs9 |
dehydrogenase/reductase 9 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DHRS9 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
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G |
Diablo |
diablo, IAP-binding mitochondrial protein |
multiple interactions |
ISO |
[Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein |
CTD |
PMID:23458895 |
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NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
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G |
Dio1 |
iodothyronine deiodinase 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of DIO1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
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G |
Dio3 |
iodothyronine deiodinase 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of DIO3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Dlat |
dihydrolipoamide S-acetyltransferase |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of DLAT protein] |
CTD |
PMID:21136691 |
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NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
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G |
Dld |
dihydrolipoamide dehydrogenase |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of DLD protein Trientine inhibits the reaction [Streptozocin results in increased expression of DLD protein] |
CTD |
PMID:21136691 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlg4 |
discs large MAGUK scaffold protein 4 |
multiple interactions decreases expression |
EXP |
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLG4 protein] |
CTD |
PMID:24333387 |
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NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153
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G |
Dlgap2 |
DLG associated protein 2 |
multiple interactions decreases expression |
EXP |
Ibuprofen inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA]; Memantine inhibits the reaction [Streptozocin results in decreased expression of DLGAP2 mRNA] |
CTD |
PMID:24333387 |
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NCBI chr16:74,786,771...75,496,402
Ensembl chr16:74,791,509...75,496,407
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G |
Dlst |
dihydrolipoamide S-succinyltransferase |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of DLST protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296
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G |
Dmbt1 |
deleted in malignant brain tumors 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of DMBT1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
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G |
Dmbt1l1 |
deleted in malignant brain tumors 1 like 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of CDCP3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:185,949,897...186,084,340
Ensembl chr 1:185,949,881...186,084,338
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G |
Dnah5 |
dynein, axonemal, heavy chain 5 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of DNAH5 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:78,937,788...79,255,551
Ensembl chr 2:78,937,800...79,254,890
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G |
Dnm1l |
dynamin 1-like |
multiple interactions increases expression |
EXP ISO |
ferulic acid inhibits the reaction [Streptozocin results in increased expression of DNM1L protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of DNM1L mRNA |
CTD |
PMID:31029786 PMID:33812996 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dnmt1 |
DNA methyltransferase 1 |
multiple interactions decreases expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT1 protein; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; Folic Acid inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA] [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 mRNA]]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in decreased expression of DNMT1 protein]] |
CTD |
PMID:28422052 PMID:29127188 PMID:36547818 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dnmt3a |
DNA methyltransferase 3 alpha |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3A protein |
CTD |
PMID:29127188 |
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NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687
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G |
Dnmt3b |
DNA methyltransferase 3 beta |
multiple interactions increases expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of DNMT3B protein Streptozocin results in increased expression of DNMT3B mRNA |
CTD |
PMID:29127188 PMID:37081038 |
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NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124
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G |
Dpp4 |
dipeptidylpeptidase 4 |
increases response to substance decreases activity decreases expression increases expression |
EXP |
DPP4 results in increased susceptibility to Streptozocin Streptozocin results in decreased activity of DPP4 protein Streptozocin results in decreased expression of DPP4 protein Streptozocin results in increased expression of DPP4 mRNA |
CTD |
PMID:16045816 PMID:18931022 |
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NCBI chr 3:46,962,233...47,043,870
Ensembl chr 3:46,962,243...47,043,901
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G |
Ece1 |
endothelin converting enzyme 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ECE1 mRNA Triterpenes inhibits the reaction [Streptozocin results in increased expression of ECE1 mRNA] |
CTD |
PMID:19000375 |
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NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
increases expression |
EXP |
Streptozocin results in increased expression of ECHS1 protein |
CTD |
PMID:21136691 |
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NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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G |
Edaradd |
EDAR associated via death domain |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EDARADD mRNA] |
CTD |
PMID:33484791 |
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NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447
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G |
Edem1 |
ER degradation enhancing alpha-mannosidase like protein 1 |
increases expression |
EXP |
Streptozocin results in increased expression of EDEM1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
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G |
Edem3 |
ER degradation enhancing alpha-mannosidase like protein 3 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA]; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 mRNA; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in decreased expression of EDEM3 protein |
CTD |
PMID:38282657 |
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NCBI chr13:63,858,282...63,920,538
Ensembl chr13:63,858,716...63,920,523
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G |
Edn1 |
endothelin 1 |
multiple interactions increases expression |
EXP ISO |
Bezafibrate inhibits the reaction [Streptozocin results in increased expression of EDN1 mRNA]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of EDN1 protein] Streptozocin results in increased expression of EDN1 mRNA; Streptozocin results in increased expression of EDN1 protein diphenyleneiodonium inhibits the reaction [Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate]]; Streptozocin promotes the reaction [EDN1 protein results in increased chemical synthesis of Inositol 1,4,5-Trisphosphate] |
CTD |
PMID:12458661 PMID:12967931 PMID:19000375 PMID:20691780 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Efna3 |
ephrin A3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of EFNA3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736
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G |
Efnb2 |
ephrin B2 |
affects expression |
ISO |
Streptozocin affects the expression of EFNB2 mRNA |
CTD |
PMID:26073000 |
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NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
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G |
Egfr |
epidermal growth factor receptor |
increases expression |
EXP |
Streptozocin results in increased expression of EGFR mRNA |
CTD |
PMID:37081038 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
increases expression |
EXP |
Streptozocin results in increased expression of EHHADH mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein] [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of EIF2AK3 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:33812996 PMID:34801538 PMID:38049026 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Eif2s1 |
eukaryotic translation initiation factor 2 subunit alpha |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:33812996 |
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NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions increases expression |
EXP |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of EIF4EBP1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Elk1 |
ETS transcription factor ELK1 |
increases phosphorylation |
EXP |
Streptozocin results in increased phosphorylation of ELK1 protein |
CTD |
PMID:12642375 |
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NCBI chr X:1,138,826...1,155,713
Ensembl chr X:1,139,756...1,155,713
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G |
Elovl7 |
ELOVL fatty acid elongase 7 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ELOVL7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:39,789,229...39,858,579
Ensembl chr 2:39,789,250...39,856,845
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G |
Eno1 |
enolase 1 |
increases expression |
EXP |
Streptozocin results in increased expression of ENO1 protein |
CTD |
PMID:24924950 |
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NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
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G |
Eno1-ps1 |
enolase 1, pseudogene 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ENO1-PS1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ENO1-PS1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 3:57,576,643...57,578,321
Ensembl chr 3:57,576,709...57,578,013
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G |
Eno2 |
enolase 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ENO2 mRNA] |
CTD |
PMID:33484791 |
|
NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
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G |
Enpep |
glutamyl aminopeptidase |
multiple interactions increases activity |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in decreased expression of ENPEP mRNA Streptozocin results in increased activity of ENPEP protein |
CTD |
PMID:25905778 PMID:28468961 |
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NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of ENPP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Ep300 |
E1A binding protein p300 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of EP300 mRNA 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of EP300 mRNA] |
CTD |
PMID:22228707 |
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NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088 Ensembl chr 7:113,106,247...113,136,088
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G |
Epcam |
epithelial cell adhesion molecule |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of EPCAM mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
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G |
Ephx1 |
epoxide hydrolase 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of EPHX1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] |
CTD |
PMID:19634143 |
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NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
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G |
Ephx2 |
epoxide hydrolase 2 |
increases expression multiple interactions decreases response to substance |
EXP ISO |
Streptozocin results in increased expression of EPHX2 protein EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased secretion of CCL2 protein] EPHX2 gene mutant form results in decreased susceptibility to Streptozocin |
CTD |
PMID:21832210 PMID:23611540 |
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NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Epo |
erythropoietin |
multiple interactions decreases expression increases expression |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of EPO protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPO mRNA]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPO protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPO mRNA] |
CTD |
PMID:19958114 PMID:20821229 PMID:34391751 |
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NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Epor |
erythropoietin receptor |
multiple interactions decreases expression increases expression |
EXP |
Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in decreased expression of EPOR protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of EPOR mRNA] Streptozocin results in increased expression of EPOR mRNA; Streptozocin results in increased expression of EPOR protein |
CTD |
PMID:19958114 PMID:20821229 |
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NCBI chr 8:20,489,678...20,494,257
Ensembl chr 8:20,489,678...20,494,257
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G |
Ercc1 |
ERCC excision repair 1, endonuclease non-catalytic subunit |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ERCC1 mRNA; Streptozocin results in increased expression of ERCC1 protein 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC1 mRNA] |
CTD |
PMID:22228707 |
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NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963
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G |
Ercc4 |
ERCC excision repair 4, endonuclease catalytic subunit |
multiple interactions increases expression |
EXP |
3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ERCC4 mRNA] Streptozocin results in increased expression of ERCC4 mRNA; Streptozocin results in increased expression of ERCC4 protein |
CTD |
PMID:22228707 |
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NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
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G |
Ermap |
erythroblast membrane associated protein (Scianna blood group) |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of ERMAP mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:132,788,847...132,803,030
Ensembl chr 5:132,789,991...132,802,847
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions increases expression |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of ERN1 protein modified form]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of ERN1 protein] [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of ERN1 protein] |
CTD |
PMID:20399799 PMID:34801538 PMID:35961541 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Ern2 |
endoplasmic reticulum to nucleus signaling 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ERN2 protein] |
CTD |
PMID:33484791 |
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NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR1 mRNA] [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of ESR1 protein Streptozocin results in increased expression of ESR1 |
CTD |
PMID:24781736 PMID:30421503 PMID:32469605 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions decreases expression |
ISO |
bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; bisphenol A inhibits the reaction [Streptozocin results in decreased expression of ESR2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of ESR2 mRNA] Streptozocin results in decreased expression of ESR2 mRNA; Streptozocin results in decreased expression of ESR2 protein |
CTD |
PMID:23471663 PMID:24781736 PMID:35051763 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Etfa |
electron transfer flavoprotein subunit alpha |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ETFA protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFA protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:55,835,115...55,891,890
Ensembl chr 8:55,835,134...55,891,969
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G |
Etfb |
electron transfer flavoprotein subunit beta |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of ETFB protein Trientine inhibits the reaction [Streptozocin results in decreased expression of ETFB protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
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G |
Etfdh |
electron transfer flavoprotein dehydrogenase |
affects expression |
ISO |
Streptozocin affects the expression of ETFDH mRNA |
CTD |
PMID:18583417 |
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NCBI chr 2:164,740,547...164,762,754
Ensembl chr 2:164,729,749...164,762,745
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
multiple interactions decreases expression |
ISO |
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Eya2 |
EYA transcriptional coactivator and phosphatase 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of EYA2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793
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G |
Ezh2 |
enhancer of zeste 2 polycomb repressive complex 2 subunit |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of EZH2 protein |
CTD |
PMID:29127188 |
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NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
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G |
F3 |
coagulation factor III, tissue factor |
decreases activity |
EXP |
Streptozocin results in decreased activity of F3 protein |
CTD |
PMID:32864810 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of FABP4 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fabp7 |
fatty acid binding protein 7 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of FABP7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
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G |
Fadd |
Fas associated via death domain |
multiple interactions increases expression |
EXP |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] |
CTD |
PMID:28856781 |
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NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fads1 |
fatty acid desaturase 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of FADS1 mRNA |
CTD |
PMID:25246140 |
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NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734
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G |
Fam184a |
family with sequence similarity 184, member A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of FAM184A mRNA |
CTD |
PMID:33484791 |
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NCBI chr20:32,934,424...33,056,626
Ensembl chr20:32,934,636...33,056,652
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G |
Fars2 |
phenylalanyl-tRNA synthetase 2, mitochondrial |
affects expression |
ISO |
Streptozocin affects the expression of FARS2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr17:28,319,215...28,746,217
Ensembl chr17:28,319,280...28,746,337
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
EXP |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] |
CTD |
PMID:28856781 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Faslg |
Fas ligand |
multiple interactions increases expression |
EXP |
Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein]; rosiglitazone inhibits the reaction [Streptozocin results in increased expression of FASLG mRNA] Streptozocin results in increased expression of FASLG mRNA; Streptozocin results in increased expression of FASLG protein |
CTD |
PMID:21791967 PMID:28856781 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fasn |
fatty acid synthase |
multiple interactions decreases expression increases expression |
EXP ISO |
Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of FASN protein]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of FASN protein] Streptozocin results in increased expression of FASN mRNA; Streptozocin results in increased expression of FASN protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of FASN mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of FASN mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA] |
CTD |
PMID:20219977 PMID:23647015 PMID:27769711 PMID:29988851 PMID:33812996 PMID:34896238 More...
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Faxc |
failed axon connections homolog, metaxin like GST domain containing |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FAXC mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 5:35,480,137...35,539,741
Ensembl chr 5:35,480,402...35,544,446
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G |
Fbp1 |
fructose-bisphosphatase 1 |
increases activity multiple interactions |
EXP |
Streptozocin results in increased activity of FBP1 protein citronellol inhibits the reaction [Streptozocin results in increased activity of FBP1 protein] |
CTD |
PMID:26944432 |
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NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
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G |
Fbp2 |
fructose-bisphosphatase 2 |
multiple interactions |
ISO |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FBP2 protein |
CTD |
PMID:25446853 |
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NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
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G |
Fbxo32 |
F-box protein 32 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of FBXO32 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of FBXO32 protein] |
CTD |
PMID:30635400 PMID:30980806 |
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NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
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G |
Fcer1g |
Fc epsilon receptor Ig |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of FCER1G mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
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G |
Fcgr2a |
Fc gamma receptor 2A |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of FCGR3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of FCGR3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967
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G |
Fgf17 |
fibroblast growth factor 17 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in increased expression of FGF17 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr15:45,711,498...45,717,622
Ensembl chr15:45,711,998...45,717,063
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G |
Fgf19 |
fibroblast growth factor 19 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of FGF15 protein |
CTD |
PMID:29382564 |
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NCBI chr 1:200,056,526...200,060,980
Ensembl chr 1:200,056,644...200,060,287
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions affects response to substance |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FGF21 mRNA; FGF21 protein affects the reaction [Streptozocin results in increased expression of AIFM1]; FGF21 protein affects the reaction [Streptozocin results in increased expression of CASP12 protein modified form]; FGF21 protein affects the reaction [Streptozocin results in increased expression of DDIT3]; Glucagon analog promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of FGF21 protein] FGF21 protein affects the susceptibility to Streptozocin |
CTD |
PMID:23499715 PMID:29127188 PMID:29988851 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
multiple interactions decreases expression |
EXP |
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of FGFR1] |
CTD |
PMID:24136780 |
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NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
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G |
Fh |
fumarate hydratase |
affects expression |
ISO |
Streptozocin affects the expression of FH1 mRNA |
CTD |
PMID:18583417 |
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NCBI chr13:87,524,331...87,550,215
Ensembl chr13:87,524,337...87,550,266
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FIS1 mRNA |
CTD |
PMID:33812996 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Fitm2 |
fat storage-inducing transmembrane protein 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of FITM2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:152,141,346...152,147,858
Ensembl chr 3:152,141,346...152,147,858
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G |
Fkbp1b |
FKBP prolyl isomerase 1B |
multiple interactions decreases expression |
ISO EXP |
Streptozocin promotes the reaction [bisphenol A results in decreased expression of FKBP1B mRNA]; Streptozocin promotes the reaction [octylphenol results in decreased expression of FKBP1B mRNA] Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of FKBP1B protein] Streptozocin results in decreased expression of FKBP1B mRNA; Streptozocin results in decreased expression of FKBP1B protein |
CTD |
PMID:19000375 PMID:29935216 |
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NCBI chr 6:27,832,128...27,850,600
Ensembl chr 6:27,838,802...27,848,653
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G |
Flacc1 |
flagellum associated containing coiled-coil domains 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of FLACC1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 9:60,315,581...60,343,692
Ensembl chr 9:60,315,582...60,343,648
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G |
Flt1 |
Fms related receptor tyrosine kinase 1 |
multiple interactions increases expression |
EXP ISO |
Simvastatin inhibits the reaction [Streptozocin results in increased expression of FLT1 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein]; Streptozocin results in increased phosphorylation of and results in increased expression of FLT1 protein |
CTD |
PMID:20821229 PMID:26073000 |
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NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626
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G |
Fmo2 |
flavin containing dimethylaniline monoxygenase 2 |
increases expression |
EXP |
Streptozocin results in increased expression of FMO2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
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G |
Fmo4 |
flavin containing dimethylaniline monoxygenase 4 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of FMO4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:75,154,683...75,172,874
Ensembl chr13:75,154,684...75,172,874
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G |
Fn1 |
fibronectin 1 |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of FN1; Streptozocin results in increased expression of FN1 mRNA; Streptozocin results in increased expression of FN1 protein 3-aminobenzamide inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1]; benazepril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Carvedilol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; esculetin inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein]; Organoselenium Compounds inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of FN1 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA] [AM6545 co-treated with Perindopril] inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 mRNA; [fatostatin co-treated with Streptozocin] results in increased expression of FN1 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of FN1 protein; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of FN1 protein]; CREB1 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of FN1 protein] |
CTD |
PMID:11798618 PMID:12140129 PMID:14586741 PMID:16973718 PMID:19895808 PMID:21300041 PMID:21450970 PMID:21998146 PMID:22228707 PMID:22733486 PMID:23376009 PMID:23611540 PMID:24413998 PMID:24877639 PMID:25057273 PMID:25240712 PMID:25301743 PMID:26341651 PMID:27292126 PMID:29420703 PMID:30184259 PMID:31009641 PMID:34310909 PMID:38282657 More...
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
formononetin inhibits the reaction [Streptozocin results in increased expression of FOS mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of FOS protein] Streptozocin results in increased expression of FOS mRNA; Streptozocin results in increased expression of FOS protein |
CTD |
PMID:35315182 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosb |
FosB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of FOSB mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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G |
Foxa2 |
forkhead box A2 |
multiple interactions |
EXP |
copper bis(3,5-diisopropylsalicylate) inhibits the reaction [Streptozocin results in decreased expression of FOXA2] |
CTD |
PMID:23795780 |
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NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
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G |
Foxo1 |
forkhead box O1 |
multiple interactions increases acetylation decreases expression decreases phosphorylation |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein; resveratrol inhibits the reaction [Streptozocin results in increased acetylation of FOXO1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of FOXO1 protein] [Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] affects the localization of FOXO1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of FOXO1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein]; Streptozocin results in increased phosphorylation of and results in decreased activity of FOXO1 protein; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of FOXO1 protein] |
CTD |
PMID:22733486 PMID:24889822 PMID:26522834 PMID:27270450 PMID:36627075 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Foxo3 |
forkhead box O3 |
decreases expression increases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of FOXO3 protein Streptozocin results in increased expression of FOXO3 protein modified form Streptozocin results in increased expression of FOXO3 protein; Streptozocin results in increased expression of FOXO3 protein modified form [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased phosphorylation of FOXO3 protein; [Streptozocin co-treated with Resveratrol] results in increased phosphorylation of FOXO3 protein; Resveratrol inhibits the reaction [Streptozocin results in increased expression of FOXO3 protein] |
CTD |
PMID:17082237 PMID:18703049 PMID:23792339 PMID:31062909 |
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NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
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G |
Fshb |
follicle stimulating hormone subunit beta |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of FSHB protein Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of FSHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of FSHB protein] [Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of FSHB protein] |
CTD |
PMID:19931367 PMID:30365938 PMID:34656705 |
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NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FTH1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FTH1 mRNA] |
CTD |
PMID:32410268 PMID:38483099 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
Ftl1 |
ferritin light chain 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of FTL1 protein |
CTD |
PMID:38483099 |
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NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
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G |
Fxyd2 |
FXYD domain-containing ion transport regulator 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of FXYD2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions decreases activity increases activity increases expression decreases expression |
EXP ISO |
4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; citronellol inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Phlorhizin inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; plumbagin inhibits the reaction [Streptozocin results in increased activity of G6PC1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of G6PC1 protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of G6PC1 protein] Streptozocin results in increased expression of G6PC1 mRNA; Streptozocin results in increased expression of G6PC1 protein Streptozocin results in decreased expression of G6PC1 mRNA [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of G6PC1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of G6PC1 mRNA]; esculetin promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PC1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of G6PC1 mRNA] |
CTD |
PMID:12446591 PMID:19634143 PMID:22960630 PMID:25446853 PMID:25641191 PMID:25905778 PMID:26522834 PMID:26616445 PMID:26944432 PMID:27038876 PMID:27769711 PMID:34896238 PMID:36627075 More...
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NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
G6pc3 |
glucose 6 phosphatase catalytic subunit 3 |
decreases activity multiple interactions |
EXP |
Streptozocin results in decreased activity of G6PC3 protein Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PC3 protein] |
CTD |
PMID:31345080 |
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NCBI chr10:87,146,987...87,151,223
Ensembl chr10:87,146,901...87,151,221
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions decreases activity decreases expression |
EXP ISO |
2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein; [Phytic Acid co-treated with Inositol] inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; [Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein; [Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; citronellol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; geraniol inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; Hesperidin inhibits the reaction [Streptozocin results in decreased activity of G6PD protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of G6PD protein] [Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of G6PD protein] Streptozocin results in decreased expression of G6PD mRNA; Streptozocin results in decreased expression of G6PD protein |
CTD |
PMID:19059388 PMID:19133311 PMID:19682444 PMID:24923654 PMID:25641191 PMID:26944432 PMID:28330423 PMID:28757134 PMID:31345080 PMID:33484791 PMID:35478295 PMID:36169646 PMID:37354076 More...
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NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GABRA4 mRNA |
CTD |
PMID:33484791 |
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NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of GABRR1 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
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G |
Gad1 |
glutamate decarboxylase 1 |
multiple interactions decreases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GAD1 protein] |
CTD |
PMID:23267840 PMID:35085591 |
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NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
multiple interactions |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of GADD45B mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of GADD45B mRNA |
CTD |
PMID:25905778 PMID:29127188 |
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NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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G |
Galt |
galactose-1-phosphate uridylyltransferase |
decreases expression |
EXP |
Streptozocin results in decreased expression of GALT mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
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G |
Gas6 |
growth arrest specific 6 |
increases expression |
EXP |
Streptozocin results in increased expression of GAS6 protein |
CTD |
PMID:12644472 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gatm |
glycine amidinotransferase |
multiple interactions decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of GATM protein] |
CTD |
PMID:19634143 |
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NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129
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G |
Gcg |
glucagon |
multiple interactions decreases expression |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA; Butyric Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GCG protein]; rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of GCG mRNA]; Sitagliptin Phosphate inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCG mRNA] |
CTD |
PMID:18998217 PMID:23466488 PMID:27270450 |
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NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gck |
glucokinase |
multiple interactions decreases expression |
ISO EXP |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein]; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of GCK protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GCK protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GCK protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GCK mRNA]; repaglinide analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCK mRNA] |
CTD |
PMID:25446853 PMID:26522834 PMID:27038876 PMID:27769711 PMID:29127188 PMID:33359794 PMID:33484791 PMID:35702883 PMID:36169646 More...
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NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions decreases expression |
EXP ISO |
[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GCLC protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GCLC protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLC mRNA] Streptozocin results in decreased expression of GCLC mRNA; Streptozocin results in decreased expression of GCLC protein |
CTD |
PMID:21439372 PMID:33359794 PMID:33639173 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GCLM mRNA |
CTD |
PMID:33359794 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Gcnt2 |
glucosaminyl (N-acetyl) transferase 2 |
increases expression |
EXP |
Streptozocin results in increased expression of GCNT2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr17:23,796,859...23,901,625
Ensembl chr17:23,796,859...23,901,611
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G |
Gda |
guanine deaminase |
increases expression |
EXP |
Streptozocin results in increased expression of GDA mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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G |
Gdnf |
glial cell derived neurotrophic factor |
multiple interactions decreases expression |
EXP |
Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of GDNF protein] |
CTD |
PMID:38049026 |
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NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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G |
Gfap |
glial fibrillary acidic protein |
multiple interactions increases expression decreases expression |
EXP ISO |
Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of GFAP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of GFAP protein] Streptozocin results in increased expression of GFAP mRNA; Streptozocin results in increased expression of GFAP protein Streptozocin results in decreased expression of GFAP protein Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein] |
CTD |
PMID:24333387 PMID:28499986 PMID:38049026 |
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NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
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G |
Gfm1 |
G elongation factor, mitochondrial 1 |
affects expression |
ISO |
Streptozocin affects the expression of GFM1 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of GGT1 protein [resveratrol co-treated with Streptozocin] results in increased expression of GGT1 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of GGT1 protein] |
CTD |
PMID:19634143 PMID:25905778 |
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NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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G |
Ghr |
growth hormone receptor |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of GHR mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735
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G |
Ghrl |
ghrelin and obestatin prepropeptide |
multiple interactions |
EXP |
GHRL protein promotes the reaction [Streptozocin results in decreased expression of CARTPT mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of FASN mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621
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G |
Gk |
glycerol kinase |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of GK mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA] |
CTD |
PMID:25905778 PMID:33812996 |
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NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631
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G |
Glb1 |
galactosidase, beta 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of GLB1 protein 2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of GLB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of GLB1 protein; ARG1 gene mutant form inhibits the reaction [Streptozocin results in increased expression of GLB1 protein] |
CTD |
PMID:29673160 PMID:38483099 |
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NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127
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G |
Glis1 |
GLIS family zinc finger 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GLIS1 mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 5:122,222,155...122,412,141
Ensembl chr 5:122,222,128...122,412,141
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G |
Glo1 |
glyoxalase 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein]; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GLO1 protein] |
CTD |
PMID:21439372 |
|
NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions |
EXP |
[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in decreased expression of GLP1R mRNA] |
CTD |
PMID:31468622 |
|
NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GLUD1 mRNA] |
CTD |
PMID:35702883 |
|
NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
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G |
Glul |
glutamate-ammonia ligase |
multiple interactions decreases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of GLUL mRNA; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of GLUL protein] Streptozocin results in decreased expression of GLUL mRNA; Streptozocin results in decreased expression of GLUL protein |
CTD |
PMID:25905778 PMID:26677078 |
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NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
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G |
Gna11 |
G protein subunit alpha 11 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNA11 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNA11 protein] |
CTD |
PMID:20691780 |
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NCBI chr 7:8,163,520...8,177,863
Ensembl chr 7:8,162,750...8,179,812
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G |
Gnai2 |
G protein subunit alpha i2 |
multiple interactions decreases expression |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein] |
CTD |
PMID:18441196 |
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NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979
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G |
Gnai3 |
G protein subunit alpha i3 |
multiple interactions decreases expression |
EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]; diphenyleneiodonium inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein] |
CTD |
PMID:18441196 |
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NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742
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G |
Gnaq |
G protein subunit alpha q |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of GNAQ protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of GNAQ protein] |
CTD |
PMID:20691780 |
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NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
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G |
Gngt1 |
G protein subunit gamma transducin 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GNGT1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:32,006,267...32,009,252
Ensembl chr 4:32,006,267...32,009,252
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G |
Gnmt |
glycine N-methyltransferase |
multiple interactions increases activity increases expression |
EXP |
Folic Acid inhibits the reaction [Streptozocin results in increased activity of GNMT protein] Streptozocin results in increased expression of GNMT mRNA; Streptozocin results in increased expression of GNMT protein |
CTD |
PMID:16835399 |
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NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
multiple interactions increases secretion |
EXP ISO |
[Resveratrol co-treated with Streptozocin] results in decreased expression of GOT1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GOT1 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GOT1 protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GOT1 protein] |
CTD |
PMID:25905778 PMID:30657622 PMID:35961541 PMID:37482253 |
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NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of GOT2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of GOT2 protein] |
CTD |
PMID:19634143 |
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NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Gpc1 |
glypican 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of GPC1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047
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G |
Gpd1 |
glycerol-3-phosphate dehydrogenase 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of GPD1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529
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G |
Gprc6a |
G protein-coupled receptor, class C, group 6, member A |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPRC6A mRNA] |
CTD |
PMID:27488359 |
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NCBI chr20:30,922,106...30,943,412
Ensembl chr20:30,922,106...30,943,412
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions increases expression increases activity increases secretion |
EXP ISO |
4-hydroxyisoleucine inhibits the reaction [Streptozocin results in increased expression of GPT protein]; [Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]]; Atorvastatin inhibits the reaction [Streptozocin results in increased secretion of GPT protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; Eugenol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Glyburide inhibits the reaction [Streptozocin results in increased activity of GPT protein]; mangiferin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; naringenin inhibits the reaction [Streptozocin results in increased activity of GPT protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased activity of GPT protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of GPT protein]; sodium tungstate(VI) inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of GPT protein]; Tribulus extract inhibits the reaction [Streptozocin results in increased activity of GPT protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein] [Acrylamide co-treated with Streptozocin] results in increased activity of GPT protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of GPT protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GPT protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of GPT protein] |
CTD |
PMID:11357483 PMID:24854284 PMID:24877639 PMID:26071184 PMID:27350165 PMID:29223569 PMID:29614383 PMID:30144451 PMID:30657622 PMID:30927557 PMID:31100278 PMID:31743741 PMID:32410268 PMID:32812462 PMID:33524429 PMID:34896238 PMID:35072544 PMID:35961541 PMID:36169646 PMID:36627075 PMID:37054934 PMID:37352119 PMID:37482253 PMID:38047382 More...
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions decreases activity decreases expression increases expression |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GPX1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX1 mRNA]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA] Streptozocin results in increased expression of GPX1 protein [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of GPX1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of GPX1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of GPX1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of GPX1 mRNA; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of GPX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of GPX1 protein] |
CTD |
PMID:18789669 PMID:19634143 PMID:23267840 PMID:24740756 PMID:30318971 PMID:33359794 PMID:33639173 PMID:35786680 PMID:37482253 More...
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gpx2 |
glutathione peroxidase 2 |
multiple interactions |
EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in increased expression of GPX2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in increased expression of GPX2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in increased expression of GPX2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of GPX2 mRNA; [Resveratrol co-treated with Streptozocin] results in increased expression of GPX2 mRNA |
CTD |
PMID:25905778 PMID:35786680 |
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NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
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G |
Gpx3 |
glutathione peroxidase 3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of GPX3 protein Trientine inhibits the reaction [Streptozocin results in increased expression of GPX3 protein] |
CTD |
PMID:19634143 |
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NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of GPX4 mRNA] |
CTD |
PMID:33359794 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gramd2a |
GRAM domain containing 2A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of GRAMD2A mRNA |
CTD |
PMID:33484791 |
|
NCBI chr 8:60,079,744...60,117,788
Ensembl chr 8:60,080,338...60,115,842
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G |
Grem1 |
gremlin 1, DAN family BMP antagonist |
increases expression |
EXP |
Streptozocin results in increased expression of GREM1 mRNA |
CTD |
PMID:10744662 |
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NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
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G |
Gria4 |
glutamate ionotropic receptor AMPA type subunit 4 |
multiple interactions increases expression |
EXP |
Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein] |
CTD |
PMID:23267840 |
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NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
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G |
Grin1 |
glutamate ionotropic receptor NMDA type subunit 1 |
multiple interactions increases expression |
EXP |
Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein] Streptozocin results in increased expression of GRIN1 mRNA; Streptozocin results in increased expression of GRIN1 protein |
CTD |
PMID:23267840 |
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NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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G |
Grm5 |
glutamate metabotropic receptor 5 |
increases expression |
EXP |
Streptozocin results in increased expression of GRM5 protein |
CTD |
PMID:19840219 |
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NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
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G |
Gsdmd |
gasdermin D |
multiple interactions increases expression affects response to substance |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein; GSDMD protein affects the reaction [Streptozocin results in increased cleavage of CASP1 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GSDMD protein]; Streptozocin results in increased expression of and results in increased cleavage of GSDMD protein GSDMD protein affects the susceptibility to Streptozocin Streptozocin results in increased expression of GSDMD protein scutellarin inhibits the reaction [Streptozocin results in increased expression of GSDMD protein] |
CTD |
PMID:34212273 PMID:37081038 PMID:37473909 |
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NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
decreases phosphorylation multiple interactions increases expression |
EXP ISO |
Streptozocin results in decreased phosphorylation of GSK3B protein [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein; Curcumin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in decreased phosphorylation of GSK3B protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of GSK3B mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of GSK3B protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; Tribulus extract inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of GSK3B protein]; Metformin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; phillyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:25541178 PMID:27038876 PMID:28422052 PMID:31877369 PMID:33484791 PMID:33812996 PMID:34428446 PMID:34455488 PMID:34649470 PMID:34922902 PMID:35442559 PMID:36627075 More...
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gspt2 |
G1 to S phase transition 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of GSPT2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr X:59,587,237...59,589,758
Ensembl chr X:59,587,276...59,594,162
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G |
Gsr |
glutathione-disulfide reductase |
multiple interactions decreases activity increases activity affects activity decreases expression |
EXP |
[Carmustine results in decreased activity of GSR protein] which results in increased susceptibility to Streptozocin; [Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein; [Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein; [Zinc Sulfate results in increased abundance of Zinc] inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Chromium inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; chromium tripicolinate inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Ellagic Acid inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased activity of GSR protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of GSR protein]; geraniol inhibits the reaction [Streptozocin affects the activity of GSR protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; Metformin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; morin inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of GSR protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased activity of GSR protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of GSR protein]; Rosiglitazone inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]]; Sodium Selenite inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Streptozocin promotes the reaction [Dietary Fats results in decreased activity of GSR protein]; Zinc inhibits the reaction [Streptozocin results in decreased activity of GSR protein] |
CTD |
PMID:11424224 PMID:15720826 PMID:17145126 PMID:19682444 PMID:19840221 PMID:20053369 PMID:20307516 PMID:20620209 PMID:21439372 PMID:22476978 PMID:22940631 PMID:23122718 PMID:24752916 PMID:24877639 PMID:26341651 PMID:26748309 PMID:29441829 PMID:30817903 PMID:31009641 PMID:32812462 PMID:32864810 PMID:33724628 PMID:34039237 PMID:35414346 PMID:37354076 More...
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of GSTA1 protein] |
CTD |
PMID:26474837 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Gsta2 |
glutathione S-transferase alpha 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of GSTA2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of GSTA2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
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G |
Gsta3 |
glutathione S-transferase alpha 3 |
multiple interactions decreases expression increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of GSTA3 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTA3 mRNA] |
CTD |
PMID:16684804 PMID:19634143 |
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NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
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G |
Gsta4 |
glutathione S-transferase alpha 4 |
increases expression |
EXP |
Streptozocin results in increased expression of GSTA4 protein |
CTD |
PMID:14693714 |
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NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of GSTA5 mRNA Streptozocin results in increased expression of GSTA5 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstm2 |
glutathione S-transferase mu 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of GSTM2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstm5 |
glutathione S-transferase, mu 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of GSTM3 mRNA] |
CTD |
PMID:21439372 |
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NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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G |
Gstm5l |
glutathione S-transferase, mu 5-like |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of GSTM5 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of GSTM5 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 2:195,544,424...195,549,895
Ensembl chr 2:195,544,426...195,628,961
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G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of GSTP1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Gucy1b2 |
guanylate cyclase 1 soluble subunit beta 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of GUCY1B2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:36,589,501...36,669,441
Ensembl chr15:36,598,883...36,669,441
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G |
Gys1 |
glycogen synthase 1 |
decreases expression multiple interactions increases phosphorylation |
EXP |
Streptozocin results in decreased expression of GYS1 mRNA Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of GYS1 mRNA]; Tribulus extract inhibits the reaction [Streptozocin results in increased phosphorylation of GYS1 protein] |
CTD |
PMID:27038876 PMID:36627075 |
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NCBI chr 1:95,915,443...95,935,292
Ensembl chr 1:95,915,443...95,935,292
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G |
Gys2 |
glycogen synthase 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of GYS2 protein] |
CTD |
PMID:19059388 |
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NCBI chr 4:175,365,054...175,406,228
Ensembl chr 4:175,365,054...175,406,228
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G |
H19 |
H19 imprinted maternally expressed transcript |
multiple interactions |
EXP |
[Resveratrol co-treated with Streptozocin] results in increased expression of H19 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134
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G |
H2bc3 |
H2B clustered histone 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of H2BC3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr17:41,380,056...41,380,686
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G |
Hamp |
hepcidin antimicrobial peptide |
multiple interactions |
EXP |
[Streptozocin co-treated with iron pentacarbonyl] results in increased expression of HAMP mRNA |
CTD |
PMID:22170771 |
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NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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G |
Hao2 |
hydroxyacid oxidase 2 |
multiple interactions decreases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of HAO2 mRNA; Trientine inhibits the reaction [Streptozocin results in decreased expression of HAO2 protein] Streptozocin results in decreased expression of HAO2 mRNA; Streptozocin results in decreased expression of HAO2 protein |
CTD |
PMID:19634143 PMID:25905778 |
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NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
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G |
Hapln1 |
hyaluronan and proteoglycan link protein 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HAPLN1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:20,631,640...20,696,388
Ensembl chr 2:20,631,640...20,693,777
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
decreases expression multiple interactions increases expression |
ISO EXP |
Streptozocin results in decreased expression of HAVCR1 mRNA [Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]; Metformin promotes the reaction [dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HAVCR1 protein]]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of HAVCR1 protein] |
CTD |
PMID:19516248 PMID:30551545 PMID:37224990 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hba-a2 |
hemoglobin alpha, adult chain 2 |
multiple interactions increases glycation |
EXP |
[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased glycosylation of HBA1 protein] Streptozocin results in increased glycation of HBA1 protein |
CTD |
PMID:19647726 PMID:21139377 |
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NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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G |
Hbb |
hemoglobin subunit beta |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of HBB-B1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of HBB-B1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of HCK mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
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G |
Hdac3 |
histone deacetylase 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of HDAC3 protein; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein]; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of FN1 protein] |
CTD |
PMID:27292126 |
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NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
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G |
Hdac5 |
histone deacetylase 5 |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of HDAC5 protein] |
CTD |
PMID:34656705 |
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NCBI chr10:87,152,978...87,187,921
Ensembl chr10:87,152,978...87,188,235
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G |
Hesx1 |
HESX homeobox 1 |
multiple interactions |
ISO |
[Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in decreased expression of HESX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HESX1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of HIF1A protein [Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HIF1A protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA]]; Ozone inhibits the reaction [Streptozocin results in increased expression of HIF1A mRNA] |
CTD |
PMID:26073000 PMID:26614261 PMID:35151640 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hk1 |
hexokinase 1 |
decreases activity multiple interactions |
EXP |
Streptozocin results in decreased activity of HK1 protein [homocastasterone analog co-treated with Streptozocin] results in increased expression of HK1 mRNA; plumbagin inhibits the reaction [Streptozocin results in decreased activity of HK1 protein] |
CTD |
PMID:22960630 PMID:28822685 |
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NCBI chr20:30,230,488...30,332,099
Ensembl chr20:30,230,486...30,332,131
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G |
Hmgb1 |
high mobility group box 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of HMGB1 mRNA manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of HMGB1 mRNA] |
CTD |
PMID:19833897 |
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NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565 Ensembl chr16:5,901,586...5,978,565
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions increases expression |
EXP ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA; [Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein; [Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in increased activity of HMGCR protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HMGCR mRNA] Streptozocin results in increased expression of HMGCR mRNA Acrylamide inhibits the reaction [Streptozocin results in increased expression of HMGCR mRNA] |
CTD |
PMID:20696151 PMID:25240712 PMID:25905778 PMID:27488359 PMID:34896238 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of HMGCS2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of HMGCS2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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G |
Hmox1 |
heme oxygenase 1 |
decreases activity multiple interactions increases expression decreases expression |
EXP ISO |
Streptozocin results in decreased activity of HMOX1 protein [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein; [cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein; [Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of HMOX1 protein]; chromium mesoporphyrin inhibits the reaction [[Streptozocin co-treated with Hemin] results in increased activity of HMOX1 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein]; cobaltiprotoporphyrin promotes the reaction [Streptozocin results in increased expression of HMOX1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of HMOX1 mRNA]; palbinone inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; Propofol inhibits the reaction [Streptozocin results in decreased activity of HMOX1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of HMOX1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; Streptozocin results in decreased expression of and results in decreased activity of HMOX1 protein; Streptozocin results in increased expression of and results in decreased activity of HMOX1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased activity of HMOX1 protein]; tin mesoporphyrin inhibits the reaction [[cobaltiprotoporphyrin co-treated with Streptozocin] results in increased expression of HMOX1 protein] Streptozocin results in increased expression of HMOX1 mRNA; Streptozocin results in increased expression of HMOX1 protein HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA; [Streptozocin co-treated with sulforaphane] results in increased expression of HMOX1; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of HMOX1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein] Streptozocin results in decreased expression of HMOX1 mRNA; Streptozocin results in decreased expression of HMOX1 protein |
CTD |
PMID:16309587 PMID:16595661 PMID:19019021 PMID:19190261 PMID:21439372 PMID:21457706 PMID:22023613 PMID:22531820 PMID:22675305 PMID:23453443 PMID:24508943 PMID:24810525 PMID:24967692 PMID:25541178 PMID:30817903 PMID:31173751 PMID:32202043 PMID:32662907 PMID:33359794 PMID:33639173 PMID:34610774 PMID:35442559 PMID:36510688 PMID:36999408 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hmox2 |
heme oxygenase 2 |
multiple interactions increases response to substance |
ISO |
cobaltiprotoporphyrin inhibits the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin]; tin mesoporphyrin promotes the reaction [HMOX2 gene mutant form results in increased susceptibility to Streptozocin] |
CTD |
PMID:16524951 |
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NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of HNF4A mRNA Acrylamide inhibits the reaction [Streptozocin results in increased expression of HNF4A mRNA] |
CTD |
PMID:34896238 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hopx |
HOP homeobox |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of HOPX mRNA |
CTD |
PMID:25905778 |
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NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909
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G |
Hp |
haptoglobin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HP mRNA] |
CTD |
PMID:33484791 |
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NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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G |
Hras |
HRas proto-oncogene, GTPase |
decreases farnesylation |
EXP |
Streptozocin results in decreased farnesylation of HRAS protein |
CTD |
PMID:19002579 |
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hsd17b10 |
hydroxysteroid (17-beta) dehydrogenase 10 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of HSD17B10 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of HSD17B10 protein] |
CTD |
PMID:21136691 |
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NCBI chr X:21,089,142...21,091,603
Ensembl chr X:21,089,122...21,109,488
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G |
Hsd17b2 |
hydroxysteroid (17-beta) dehydrogenase 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of HSD17B2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
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G |
Hsd17b4 |
hydroxysteroid (17-beta) dehydrogenase 4 |
affects expression |
ISO |
Streptozocin affects the expression of HSD17B4 mRNA |
CTD |
PMID:18583417 |
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NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
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G |
Hsd3b3 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 |
affects expression |
ISO |
Streptozocin affects the expression of HSD3B3 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
EXP |
Streptozocin results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:37081038 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of HSP90B1 mRNA streptozocin increases expression of Hsp90b1 protein in heart |
CTD RGD |
PMID:26522834 PMID:36044268 |
RGD:156430337 |
NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa2 |
heat shock protein family A (Hsp70) member 2 |
affects expression |
ISO |
Streptozocin affects the expression of HSPA2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions decreases expression increases expression increases expression |
EXP ISO |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 mRNA]; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of HSPA5 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein]; Streptozocin results in increased expression of and results in increased secretion of HSPA5 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA5 protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of HSPA5 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of HSPA5 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of HSPA5 protein] streptozocin increases expression of Hspa5 protein in heart |
CTD RGD |
PMID:19634143 PMID:24967692 PMID:26522834 PMID:27664441 PMID:30980806 PMID:33812996 PMID:34801538 PMID:37054934 PMID:38049026 PMID:38282657 PMID:36044268 More...
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RGD:156430337 |
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of HSPA9 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPA9 protein] |
CTD |
PMID:19634143 |
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NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases phosphorylation |
EXP |
baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of HSPB1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of HSPB1 protein] |
CTD |
PMID:18204486 PMID:34414639 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions increases expression decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPD1 protein]; Trientine inhibits the reaction [Streptozocin results in increased expression of HSPD1 protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
multiple interactions decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of HSPE1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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G |
Hspg2 |
heparan sulfate proteoglycan 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of HSPG2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of HSPG2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594
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G |
Htr1a |
5-hydroxytryptamine receptor 1A |
multiple interactions |
EXP |
Streptozocin inhibits the reaction [8-Hydroxy-2-(di-n-propylamino)tetralin results in increased activity of HTR1A protein] |
CTD |
PMID:18622176 |
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NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442
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G |
Htr2a |
5-hydroxytryptamine receptor 2A |
multiple interactions |
EXP |
Streptozocin inhibits the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased activity of HTR2A protein] |
CTD |
PMID:18622176 |
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NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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G |
Htr2c |
5-hydroxytryptamine receptor 2C |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of HTR2C mRNA |
CTD |
PMID:33484791 |
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NCBI chr X:110,640,777...110,870,288
Ensembl chr X:110,641,153...110,870,287
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G |
Iapp |
islet amyloid polypeptide |
multiple interactions decreases expression |
EXP ISO |
rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of IAPP mRNA] [octylphenol co-treated with Streptozocin] results in decreased expression of IAPP mRNA; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of IAPP mRNA] |
CTD |
PMID:18998217 PMID:29935216 |
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NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions increases expression |
ISO EXP |
AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA] Streptozocin results in increased expression of ICAM1 mRNA; Streptozocin results in increased expression of ICAM1 protein [Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein] |
CTD |
PMID:10485912 PMID:14871415 PMID:15892581 PMID:16129698 PMID:16139267 PMID:17589825 PMID:17724226 PMID:19246972 PMID:19279317 PMID:22058332 PMID:23376009 PMID:24513509 PMID:24967692 PMID:27664441 PMID:28700904 PMID:30184259 More...
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Id2 |
inhibitor of DNA binding 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of ID2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
affects expression |
ISO |
Streptozocin affects the expression of IDH2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Ifitm3 |
interferon induced transmembrane protein 3 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of IFITM3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
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G |
Ifng |
interferon gamma |
multiple interactions increases expression decreases expression |
ISO EXP |
Clodronic Acid inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IFNG mRNA] Streptozocin results in increased expression of IFNG mRNA; Streptozocin results in increased expression of IFNG protein arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IFNG protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IFNG protein] |
CTD |
PMID:11357882 PMID:15862027 PMID:15892581 PMID:15975818 PMID:18789669 PMID:20053369 PMID:25541178 More...
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igdcc4 |
immunoglobulin superfamily, DCC subclass, member 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of IGDCC4 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 8:65,621,893...65,657,651
Ensembl chr 8:65,621,897...65,657,648
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G |
Igf1 |
insulin-like growth factor 1 |
multiple interactions decreases expression increases expression |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IGF1 mRNA]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of BAX protein]; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein] Streptozocin results in decreased expression of IGF1 mRNA; Streptozocin results in decreased expression of IGF1 protein Streptozocin results in increased expression of IGF1 protein [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IGF1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IGF1 protein]] |
CTD |
PMID:7637645 PMID:9868179 PMID:11375343 PMID:23927877 PMID:25617479 PMID:32805344 PMID:33359794 PMID:36999408 More...
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Igf1r |
insulin-like growth factor 1 receptor |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of IGF1R protein [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of IGF1R protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of IGF1R protein] [Streptozocin co-treated with CNR1 protein] affects the expression of IGF1R protein |
CTD |
PMID:23562514 PMID:30721768 PMID:36547818 |
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NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777
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G |
Igf2bp3 |
insulin-like growth factor 2 mRNA binding protein 3 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of IGF2BP3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865
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G |
Igf2r |
insulin-like growth factor 2 receptor |
increases expression multiple interactions increases response to substance |
EXP |
Streptozocin results in increased expression of IGF2R protein [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Cholesterol; [IGF2R protein alternative form results in increased susceptibility to Streptozocin] which results in increased abundance of Triglycerides; [Streptozocin co-treated with IGF2R protein modified form] results in increased expression of CASP3 protein modified form; IGF2R protein modified form inhibits the reaction [Streptozocin results in increased expression of CASP9 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of BCL2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [IGF2R protein alternative form results in increased abundance of Triglycerides]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of BCL2 protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form] |
CTD |
PMID:35993117 PMID:36462176 |
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NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
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G |
Igfbp2 |
insulin-like growth factor binding protein 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of IGFBP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
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G |
Igfbp3 |
insulin-like growth factor binding protein 3 |
multiple interactions increases expression |
ISO |
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of IGFBP3 mRNA] |
CTD |
PMID:29673160 |
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NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
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G |
Igfbp7 |
insulin-like growth factor binding protein 7 |
increases expression |
ISO |
Streptozocin results in increased expression of IGFBP7 mRNA |
CTD |
PMID:29673160 |
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NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
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G |
Igsf6 |
immunoglobulin superfamily, member 6 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of IGSF6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:175,610,167...175,620,662
Ensembl chr 1:175,610,167...175,620,722
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of IKBKB protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IKBKB protein] |
CTD |
PMID:34610774 |
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NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
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G |
Il10 |
interleukin 10 |
decreases expression multiple interactions increases expression |
ISO EXP |
Streptozocin results in decreased expression of IL10 mRNA [Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL10 protein; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of IL10 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of IL10 protein] Streptozocin results in decreased expression of IL10 mRNA; Streptozocin results in decreased expression of IL10 protein Streptozocin results in increased expression of IL10 mRNA 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein]; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IL10 protein] Streptozocin results in increased expression of IL10 protein |
CTD |
PMID:15862027 PMID:32662907 PMID:33524429 PMID:33639173 PMID:35085591 PMID:37120126 PMID:38084638 More...
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il12b |
interleukin 12B |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of IL12B mRNA Dronabinol inhibits the reaction [Streptozocin results in increased expression of IL12B mRNA] |
CTD |
PMID:11357882 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
EXP |
stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased expression of IL17A protein]] |
CTD |
PMID:23611540 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
multiple interactions increases expression |
EXP ISO |
[Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] Streptozocin results in increased expression of IL18 mRNA; Streptozocin results in increased expression of IL18 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL18 protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA] |
CTD |
PMID:23647015 PMID:28322830 PMID:29291386 PMID:32202043 PMID:34212273 PMID:35961541 PMID:37081038 PMID:37473909 More...
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Streptozocin co-treated with bisphenol A] results in increased expression of IL1A mRNA; [Streptozocin co-treated with Ethinyl Estradiol] results in increased expression of IL1A mRNA; [Streptozocin co-treated with octylphenol] results in increased expression of IL1A mRNA |
CTD |
PMID:24781736 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] [Chlorpyrifos co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B mRNA]; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL1B protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; GSDMD protein affects the reaction [Streptozocin results in increased expression of IL1B protein]; Hirudins inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA] Streptozocin results in increased expression of IL1B mRNA; Streptozocin results in increased expression of IL1B protein 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL1B protein]; [Resveratrol co-treated with Streptozocin] results in increased expression of IL1B mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein; [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL1B mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL1B protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of IL1B protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IL1B protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of IL1B protein]]; myrtenol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL1B protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL1B protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL1B protein]; Streptozocin results in increased expression of and results in increased secretion of IL1B protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IL1B protein] |
CTD |
PMID:12123627 PMID:16129698 PMID:17167242 PMID:17589825 PMID:18789669 PMID:20307516 PMID:20446767 PMID:20643114 PMID:21439372 PMID:23647015 PMID:24877639 PMID:25541178 PMID:25635252 PMID:25905778 PMID:26341651 PMID:27702591 PMID:28259689 PMID:28322830 PMID:30481507 PMID:30611788 PMID:30642005 PMID:30802477 PMID:30817903 PMID:31726037 PMID:32202043 PMID:33524429 PMID:33639173 PMID:34212273 PMID:34477272 PMID:34896238 PMID:34964214 PMID:35085591 PMID:35305976 PMID:35442559 PMID:35961541 PMID:36462176 PMID:36504472 PMID:36510688 PMID:36547818 PMID:37224990 PMID:37473909 PMID:37482253 PMID:38084638 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rl1 |
interleukin 1 receptor-like 1 |
multiple interactions |
EXP |
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL1RL1 mRNA |
CTD |
PMID:31726037 |
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NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256
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G |
Il1rn |
interleukin 1 receptor antagonist |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of IL1RN mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il2 |
interleukin 2 |
multiple interactions decreases expression |
EXP |
arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of IL2 protein] |
CTD |
PMID:20053369 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il23a |
interleukin 23 subunit alpha |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of IL23A protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL23A protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL23A protein] |
CTD |
PMID:34428446 |
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NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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G |
Il27 |
interleukin 27 |
multiple interactions increases expression |
ISO |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of IL27 protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of IL27 protein] |
CTD |
PMID:34428446 |
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NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
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G |
Il33 |
interleukin 33 |
multiple interactions |
EXP |
7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL33 protein |
CTD |
PMID:31726037 |
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NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
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G |
Il4 |
interleukin 4 |
multiple interactions decreases expression |
EXP |
resveratrol inhibits the reaction [Streptozocin results in decreased expression of IL4] |
CTD |
PMID:25191525 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6 |
interleukin 6 |
increases expression increases secretion multiple interactions decreases expression |
EXP ISO |
Streptozocin results in increased expression of IL6 mRNA; Streptozocin results in increased expression of IL6 protein Streptozocin results in increased secretion of IL6 protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; [Dietary Fats co-treated with Streptozocin co-treated with Plant Extracts] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Propolis co-treated with Streptozocin] results in increased secretion of IL6 protein; [Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of IL6 protein; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of IL6 protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; mangiferin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of IL6 protein]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; pinitol inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased secretion of IL6 protein]; Propolis inhibits the reaction [Streptozocin results in increased secretion of IL6 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of IL6 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of IL6 protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of IL6 protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL6 protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of IL6 protein]; Streptozocin results in increased expression of and results in increased secretion of IL6 protein 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein; [Streptozocin co-treated with Dextran Sulfate] results in increased expression of IL6 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of IL6 protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of IL6 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of IL6 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL6 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL6 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL6 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of IL6 protein] |
CTD |
PMID:17167242 PMID:17854708 PMID:18999900 PMID:20307516 PMID:20643114 PMID:21439094 PMID:21439372 PMID:21457706 PMID:21912612 PMID:24760747 PMID:24877639 PMID:26341651 PMID:26748309 PMID:27664441 PMID:27769711 PMID:28700904 PMID:28904557 PMID:29181404 PMID:29233026 PMID:29266779 PMID:29409856 PMID:29988851 PMID:30481507 PMID:30611788 PMID:30642005 PMID:30802477 PMID:30817903 PMID:31323227 PMID:31400774 PMID:31696645 PMID:31726037 PMID:32554039 PMID:33631230 PMID:33639173 PMID:33724628 PMID:34610774 PMID:34896238 PMID:34922902 PMID:34964214 PMID:35085591 PMID:35305976 PMID:36462176 PMID:36510688 PMID:36650709 PMID:37044004 PMID:37482253 PMID:38084638 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6st |
interleukin 6 cytokine family signal transducer |
affects expression |
ISO |
Streptozocin affects the expression of IL6ST mRNA |
CTD |
PMID:26073000 |
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NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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G |
Ilk |
integrin-linked kinase |
multiple interactions increases activity |
EXP |
notoginsenoside R1 inhibits the reaction [Streptozocin results in increased activity of ILK protein] |
CTD |
PMID:25503068 |
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NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
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G |
Impa2 |
inositol monophosphatase 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of IMPA2 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of IMPA2 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
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G |
Inava |
innate immunity activator |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of INAVA mRNA |
CTD |
PMID:33484791 |
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NCBI chr13:47,666,446...47,687,383
Ensembl chr13:47,666,447...47,686,729
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G |
Inhbb |
inhibin subunit beta B |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of INHBB mRNA |
CTD |
PMID:29127188 |
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NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832
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G |
Inpp5k |
inositol polyphosphate-5-phosphatase K |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA] |
CTD |
PMID:33812996 |
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NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
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G |
Ins1 |
insulin 1 |
decreases secretion increases secretion increases expression multiple interactions decreases response to substance decreases expression |
EXP ISO |
Streptozocin results in decreased secretion of INS1 protein Streptozocin results in increased secretion of INS1 protein Streptozocin results in increased expression of INS1 mRNA; Streptozocin results in increased expression of INS1 protein [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein]; [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of CAT mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; AM 251 inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Carnosine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; CNR1 protein promotes the reaction [Streptozocin results in decreased expression of INS1 protein]; Dronabinol inhibits the reaction [Streptozocin results in decreased expression of INS1]; Edaravone inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Ethinyl Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; INS1 inhibits the reaction [[Streptozocin co-treated with APOE mutant form] results in increased abundance of Glucosamine]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of DNMT1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; PQQ Cofactor inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Streptozocin inhibits the reaction [Glucose results in increased secretion of INS1 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein] Streptozocin results in decreased susceptibility to INS1 protein Streptozocin results in decreased expression of INS1 protein; Streptozocin results in decreased expression of INS1 protein modified form Streptozocin results in decreased expression of INS1; Streptozocin results in decreased expression of INS1 protein ALPK1 protein promotes the reaction [Streptozocin results in decreased secretion of INS1 protein] 4-hydroxyisoleucine inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-hydroxyphenylethanol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in decreased expression of ACE2 protein]; [INS1 protein co-treated with Pravastatin] inhibits the reaction [Streptozocin results in increased expression of ACE protein]; [Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein; [Plant Extracts co-treated with glimepiride] inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; [Propolis co-treated with Chlorpyrifos] inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased expression of INS1 protein]; [Propolis co-treated with Streptozocin] promotes the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; [Propolis co-treated with Streptozocin] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein; [Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein; [Streptozocin co-treated with Fructose] results in increased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein; [Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein; [Streptozocin co-treated with Sodium Glutamate] results in decreased expression of INS1 protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of INS1 protein]; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]]; anthranilic acid analog inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; baicalin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Butyric Acid inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; caryophyllene inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; citronellol inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; corilagin inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; costunolide inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; coumarin inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in decreased expression of INS1 protein]; coumarin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; crocin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; Diosgenin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Estradiol inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; geraniol inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Gliclazide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; glimepiride inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Glyburide inhibits the reaction [Streptozocin results in increased secretion of INS1 protein]; Imatinib Mesylate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GAD1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of GPX1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased activity of CAT protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of BAX mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CASP8 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of COL3A1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of CYP8B1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIA4 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of GRIN1 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Lithium Carbonate inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Melatonin affects the reaction [Streptozocin results in decreased expression of INS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein]; morin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of INS1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Coconut Oil co-treated with Cholesterol] results in increased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased secretion of INS1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of INS1 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INS1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Rosiglitazone promotes the reaction [Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]]; S-allylcysteine inhibits the reaction [Streptozocin results in decreased secretion of INS1 protein]; Streptozocin affects the reaction [Chlorpyrifos results in decreased secretion of INS1 protein]; Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]; Streptozocin inhibits the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin promotes the reaction [Dietary Fats results in increased expression of INS1 protein]; Streptozocin results in decreased expression of and results in decreased secretion of INS1 protein; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INS1 protein]; thymoquinone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased secretion of INS1 protein]; TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]]; Tribulus extract inhibits the reaction [Streptozocin results in decreased expression of INS1 protein]; Warfarin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased secretion of INS1 protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS1 protein] |
CTD |
PMID:6337899 PMID:7564366 PMID:9868179 PMID:10393316 PMID:10700396 PMID:11357483 PMID:11357882 PMID:11766996 PMID:16118471 PMID:16380481 PMID:18291360 PMID:18998217 PMID:19007766 PMID:19071154 PMID:19647726 PMID:20711301 PMID:20801139 PMID:20951120 PMID:21382363 PMID:21630391 PMID:21799698 PMID:22675305 PMID:22960630 PMID:23267840 PMID:23884884 PMID:24001619 PMID:24530320 PMID:24854284 PMID:24923654 PMID:25362599 PMID:25446853 PMID:25541178 PMID:25617479 PMID:25635252 PMID:25641191 PMID:25999625 PMID:26064446 PMID:26071184 PMID:26286522 PMID:26343954 PMID:26522834 PMID:26616445 PMID:26700463 PMID:26721197 PMID:26748309 PMID:26944432 PMID:26967640 PMID:27038876 PMID:27350165 PMID:27417257 PMID:27488359 PMID:27542954 PMID:27769711 PMID:28330423 PMID:28422052 PMID:28625491 PMID:29216956 PMID:29233026 PMID:29274332 PMID:29409856 PMID:29441829 PMID:29614383 PMID:29682576 PMID:29935216 PMID:29953732 PMID:29988851 PMID:30582900 PMID:30802477 PMID:30817903 PMID:30927557 PMID:31400774 PMID:31877369 PMID:32202043 PMID:32410268 PMID:32554039 PMID:32662907 PMID:32710900 PMID:33359794 PMID:33450223 PMID:33484791 PMID:33724628 PMID:34352274 PMID:34414639 PMID:34455488 PMID:34470562 PMID:34656705 PMID:35072544 PMID:35305976 PMID:35414346 PMID:35457000 PMID:35702883 PMID:36169646 PMID:36510688 PMID:36627075 PMID:36650709 PMID:37044004 PMID:37337224 PMID:37566541 PMID:38049026 PMID:38084638 More...
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions decreases expression |
ISO EXP |
INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of INS2 mRNA; [Diethylhexyl Phthalate co-treated with Streptozocin co-treated with Dietary Fats] results in increased expression of INS2 mRNA; [Glyburide co-treated with Streptozocin] results in increased secretion of INS protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of INS2 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of INS2 mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of ATP7A protein] Streptozocin results in decreased expression of INS protein [Berberine co-treated with Streptozocin] results in increased secretion of INS protein; INS protein inhibits the reaction [Streptozocin results in decreased expression of FASN mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of AGRP mRNA]; INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in increased activity of GSR protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA] |
CTD |
PMID:11216864 PMID:15066220 PMID:19388005 PMID:20219977 PMID:22940631 PMID:23884884 PMID:25808216 PMID:33359794 PMID:33484791 More...
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insig1 |
insulin induced gene 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of INSIG1 mRNA |
CTD |
PMID:33359794 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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G |
Insig2 |
insulin induced gene 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of INSIG2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
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G |
Insr |
insulin receptor |
affects expression decreases expression decreases phosphorylation increases expression multiple interactions increases expression |
EXP ISO |
Streptozocin affects the expression of INSR protein Streptozocin results in decreased expression of INSR mRNA; Streptozocin results in decreased expression of INSR protein Streptozocin results in decreased phosphorylation of INSR protein Streptozocin results in increased expression of INSR mRNA [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of INSR protein; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of INSR protein; Metformin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; puerarin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA] resveratrol inhibits the reaction [Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein]]; Streptozocin inhibits the reaction [INS protein results in increased phosphorylation of INSR protein] [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Estradiol affects the reaction [Streptozocin affects the expression of INSR protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Melatonin inhibits the reaction [Streptozocin results in decreased expression of INSR protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin co-treated with Ovalbumin] results in decreased expression of INSR protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSR protein]; Progesterone affects the reaction [Streptozocin affects the expression of INSR protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of INSR protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of INSR mRNA]]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of INSR protein] streptozocin increases expression of hepatic mRNA |
CTD RGD |
PMID:9243097 PMID:17068109 PMID:18331706 PMID:19705549 PMID:21439094 PMID:23562514 PMID:23927877 PMID:25446853 PMID:25808216 PMID:26286522 PMID:26522834 PMID:29614383 PMID:32805344 PMID:33359794 PMID:36547818 PMID:37566541 PMID:1280238 More...
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RGD:15036814 |
NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Insrr |
insulin receptor-related receptor |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of INSRR mRNA] |
CTD |
PMID:33359794 |
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NCBI chr 2:173,255,335...173,274,800
Ensembl chr 2:173,255,414...173,274,800
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
multiple interactions increases expression |
EXP |
Glyburide inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of IRAK1 protein] |
CTD |
PMID:36504472 |
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NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Irf2 |
interferon regulatory factor 2 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of IRF2 mRNA Hirudins inhibits the reaction [Streptozocin results in increased expression of IRF2 mRNA] |
CTD |
PMID:34212273 |
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NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024
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G |
Irs1 |
insulin receptor substrate 1 |
multiple interactions decreases expression decreases phosphorylation |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of IRS1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Metformin promotes the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of IRS1 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] affects the phosphorylation of IRS1 protein] [Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein; [Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of IRS1 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in decreased phosphorylation of IRS1 protein]; Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS1 protein]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of IRS1 mRNA]] Streptozocin results in decreased expression of IRS1 mRNA; Streptozocin results in decreased expression of IRS1 protein |
CTD |
PMID:23927877 PMID:24923654 PMID:26071184 PMID:26286522 PMID:26522834 PMID:31743741 PMID:32805344 PMID:33359794 PMID:33484791 PMID:34455488 PMID:36169646 More...
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NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions decreases expression |
EXP ISO |
[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of IRS2 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of IRS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of IRS2 mRNA] Streptozocin results in decreased expression of IRS2 mRNA; Streptozocin results in decreased expression of IRS2 protein [Streptozocin co-treated with bisphenol A] results in decreased expression of IRS2 mRNA; [Streptozocin co-treated with octylphenol] results in decreased expression of IRS2 mRNA |
CTD |
PMID:24923654 PMID:26071184 PMID:26286522 PMID:27417257 PMID:29935216 PMID:33724628 PMID:37566541 More...
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NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Isyna1 |
inositol-3-phosphate synthase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ISYNA1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
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G |
Itga3 |
integrin subunit alpha 3 |
multiple interactions decreases expression |
ISO EXP |
notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGA3 protein] Streptozocin results in decreased expression of ITGA3 mRNA; Streptozocin results in decreased expression of ITGA3 protein |
CTD |
PMID:25503068 |
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NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
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G |
Itgal |
integrin subunit alpha L |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of ITGAL mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein] |
CTD |
PMID:16129698 PMID:25905778 |
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NCBI chr 1:181,918,183...181,955,735
Ensembl chr 1:181,918,183...181,955,732
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G |
Itgam |
integrin subunit alpha M |
multiple interactions increases expression |
EXP |
Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM mRNA]; Memantine inhibits the reaction [Streptozocin results in increased expression of ITGAM protein] Streptozocin results in increased expression of ITGAM mRNA; Streptozocin results in increased expression of ITGAM protein |
CTD |
PMID:16129698 PMID:24333387 |
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NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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G |
Itgav |
integrin subunit alpha V |
affects expression |
ISO |
Streptozocin affects the expression of ITGAV mRNA |
CTD |
PMID:26073000 |
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NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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G |
Itgb1 |
integrin subunit beta 1 |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of ITGB1 mRNA; Streptozocin results in decreased expression of ITGB1 protein notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 mRNA]; notoginsenoside R1 inhibits the reaction [Streptozocin results in decreased expression of ITGB1 protein] |
CTD |
PMID:25503068 |
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NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
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G |
Itgb2 |
integrin subunit beta 2 |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of ITGB2 mRNA; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein] |
CTD |
PMID:16129698 PMID:25905778 |
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NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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G |
Itpr3 |
inositol 1,4,5-trisphosphate receptor, type 3 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of ITPR3 mRNA [bisphenol A co-treated with Streptozocin] results in increased expression of ITPR3 mRNA; [octylphenol co-treated with Streptozocin] results in increased expression of ITPR3 mRNA |
CTD |
PMID:29935216 |
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NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
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G |
Jak2 |
Janus kinase 2 |
multiple interactions increases expression |
EXP |
7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of JAK2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of JAK2 protein] Streptozocin results in increased expression of JAK2 mRNA; Streptozocin results in increased expression of JAK2 protein |
CTD |
PMID:34391751 PMID:36650709 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
EXP ISO |
resveratrol inhibits the reaction [Streptozocin results in increased expression of JUN protein] formononetin inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of JUN protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein] Streptozocin results in increased expression of JUN mRNA; Streptozocin results in increased expression of JUN protein |
CTD |
PMID:26499206 PMID:28478229 PMID:30642005 PMID:35315182 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kcnab3 |
potassium voltage-gated channel subfamily A regulatory beta subunit 3 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA; ginsenoside Rh4 affects the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNAB3 mRNA] |
CTD |
PMID:33359794 |
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NCBI chr10:54,047,830...54,056,401
Ensembl chr10:54,047,825...54,054,174
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G |
Kcnh1 |
potassium voltage-gated channel subfamily H member 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KCNH1 mRNA] |
CTD |
PMID:33359794 |
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NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740
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G |
Kcnn2 |
potassium calcium-activated channel subfamily N member 2 |
increases expression |
ISO |
Streptozocin results in increased expression of KCNN2 protein |
CTD |
PMID:30635400 |
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NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347
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G |
Kcnn4 |
potassium calcium-activated channel subfamily N member 4 |
increases expression multiple interactions |
EXP ISO |
Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue exendin-4 inhibits the reaction [Streptozocin increases expression of Kcnn4 mRNA and protein in thoracic aorta smooth muscle tissue] streptozocin cotreated with high fat diet increases expression of Kcnn4 protein in aorta |
RGD |
PMID:29167619 PMID:29167619 PMID:35149165 |
RGD:401784495, RGD:401784495, RGD:401784497 |
NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
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G |
Kcnt1 |
potassium sodium-activated channel subfamily T member 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of KCNT1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:8,682,964...8,736,615
Ensembl chr 3:8,682,113...8,736,667
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G |
Kdr |
kinase insert domain receptor |
multiple interactions increases expression |
EXP ISO |
Simvastatin inhibits the reaction [Streptozocin results in increased expression of KDR mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein]; Streptozocin results in increased phosphorylation of and results in increased expression of KDR protein Streptozocin results in increased expression of KDR mRNA; Streptozocin results in increased expression of KDR protein [Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of KDR protein] |
CTD |
PMID:15643138 PMID:20821229 PMID:27097221 |
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NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions decreases expression increases expression |
EXP ISO |
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of KEAP1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in decreased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of KEAP1 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; rhapontin inhibits the reaction [Streptozocin results in increased expression of KEAP1 protein] Streptozocin results in increased expression of KEAP1 mRNA; Streptozocin results in increased expression of KEAP1 protein 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; [Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of KEAP1 mRNA]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of KEAP1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEAP1 protein] |
CTD |
PMID:21439372 PMID:30817903 PMID:32662907 PMID:33639173 PMID:34610774 PMID:34896238 PMID:36510688 PMID:37120126 More...
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Kel |
Kell metallo-endopeptidase (Kell blood group) |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of KEL mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:70,568,241...70,585,666
Ensembl chr 4:70,568,243...70,585,631
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G |
Kl |
Klotho |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of KL rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of KL] |
CTD |
PMID:24136780 |
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NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Klf15 |
KLF transcription factor 15 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of KLF15 protein]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of CCN2 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FN1 protein]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; KLF15 gene mutant form results in increased susceptibility to [Dietary Fats co-treated with Streptozocin] |
CTD |
PMID:34310909 |
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NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374
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G |
Klf4 |
KLF transcription factor 4 |
multiple interactions |
EXP |
[Resveratrol co-treated with Streptozocin] results in increased expression of KLF4 mRNA; [Streptozocin co-treated with Niacinamide] promotes the reaction [Dronabinol results in increased expression of KLF4 mRNA] |
CTD |
PMID:25905778 PMID:31081965 |
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NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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G |
Klk1 |
kallikrein 1 |
multiple interactions increases expression |
EXP ISO |
KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ICAM1 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAL protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGAM protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of ITGB2 protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein] Streptozocin results in increased expression of KLK1 mRNA |
CTD |
PMID:16129698 PMID:19516248 |
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NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754
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G |
Kng1 |
kininogen 1 |
multiple interactions increases response to substance |
EXP |
Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of Dinoprostone]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form] Streptozocin results in increased susceptibility to KNG1 protein modified form |
CTD |
PMID:20832942 |
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NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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G |
Krt19 |
keratin 19 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of KRT19 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
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G |
Kynu |
kynureninase |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of KYNU mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488
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G |
Lama1 |
laminin subunit alpha 1 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of LAMA1 protein |
CTD |
PMID:38282657 |
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NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478
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G |
Lamp1 |
lysosomal-associated membrane protein 1 |
multiple interactions |
EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP1 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP1 mRNA |
CTD |
PMID:35786680 |
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NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
multiple interactions |
EXP |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of LAMP2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of LAMP2 mRNA; [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of LAMP2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of LAMP2 mRNA |
CTD |
PMID:35786680 |
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NCBI chr X:117,173,097...117,222,090
Ensembl chr X:117,057,606...117,260,522
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G |
Lap3 |
leucine aminopeptidase 3 |
affects expression |
ISO |
Streptozocin affects the expression of LAP3 mRNA |
CTD |
PMID:18583417 |
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NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
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G |
Laptm5 |
lysosomal protein transmembrane 5 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of LAPTM5 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807
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G |
Lcat |
lecithin cholesterol acyltransferase |
multiple interactions |
EXP ISO |
[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LCAT protein] [Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LCAT protein] |
CTD |
PMID:20696151 PMID:25240712 PMID:33484791 |
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NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Lcn2 |
lipocalin 2 |
multiple interactions |
EXP ISO |
[Resveratrol co-treated with Streptozocin] results in increased expression of LCN2 mRNA; [Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein; [Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of LCN2 protein]; palmidrol analog inhibits the reaction [[Streptozocin co-treated with iomeprol] results in increased expression of LCN2 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LCN2 mRNA] |
CTD |
PMID:25905778 PMID:26474837 PMID:30551545 PMID:33484791 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Ldhb |
lactate dehydrogenase B |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of LDHB protein Trientine inhibits the reaction [Streptozocin results in increased expression of LDHB protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions decreases expression |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA; Acrylamide inhibits the reaction [Streptozocin results in decreased expression of LDLR mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LDLR mRNA] |
CTD |
PMID:33359794 PMID:34896238 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lep |
leptin |
multiple interactions |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of LEP protein] [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of LEP protein]; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LEP protein] |
CTD |
PMID:24854284 PMID:29988851 PMID:32410268 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lepr |
leptin receptor |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of LEPR mRNA |
CTD |
PMID:29127188 |
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NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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G |
Lgals3 |
galectin 3 |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of LGALS3 mRNA; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LGALS3 mRNA] |
CTD |
PMID:16684804 PMID:25905778 |
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NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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G |
Lhb |
luteinizing hormone subunit beta |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of LHB protein Sildenafil Citrate inhibits the reaction [Streptozocin results in decreased expression of LHB protein]; vitexin inhibits the reaction [Streptozocin results in decreased expression of LHB protein] [Streptozocin co-treated with Fructose] results in decreased expression of LHB protein; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of LHB protein] |
CTD |
PMID:19931367 PMID:30365938 PMID:34656705 |
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NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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G |
Limk2 |
LIM domain kinase 2 |
increases phosphorylation multiple interactions |
EXP |
Streptozocin results in increased phosphorylation of LIMK2 protein fasudil inhibits the reaction [Streptozocin results in increased phosphorylation of LIMK2 protein] |
CTD |
PMID:22062134 |
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NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of LIPC protein] |
CTD |
PMID:33484791 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipe |
lipase E, hormone sensitive type |
multiple interactions increases expression |
EXP |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LIPE mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310
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G |
Litaf |
lipopolysaccharide-induced TNF factor |
decreases expression |
EXP |
Streptozocin results in decreased expression of LITAF mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
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G |
Lpin2 |
lipin 2 |
increases expression |
EXP |
Streptozocin results in increased expression of LPIN2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
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G |
Lpl |
lipoprotein lipase |
multiple interactions |
EXP ISO |
[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein; [tetrahydrocurcumin co-treated with Chlorogenic Acid] results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; Chlorogenic Acid results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein]; tetrahydrocurcumin results in decreased susceptibility to [[Streptozocin co-treated with Niacinamide] results in decreased activity of LPL protein] [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of LPL mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of LPL mRNA |
CTD |
PMID:20696151 PMID:25240712 PMID:25446853 PMID:29127188 |
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NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
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G |
Lrp5 |
LDL receptor related protein 5 |
affects expression |
ISO |
Streptozocin affects the expression of LRP5 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:200,814,247...200,917,581
Ensembl chr 1:200,814,250...200,917,581
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G |
Lst1 |
leukocyte specific transcript 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of LST1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
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G |
Lyz2 |
lysozyme 2 |
multiple interactions increases expression |
EXP |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of LYZ mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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G |
Mafa |
MAF bZIP transcription factor A |
multiple interactions decreases expression |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MAFA mRNA]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of MAFA mRNA] |
CTD |
PMID:24781736 PMID:29935216 PMID:33359794 |
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NCBI chr 7:107,432,292...107,435,084
Ensembl chr 7:107,433,605...107,434,690
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G |
Mak |
male germ cell-associated kinase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MAK mRNA |
CTD |
PMID:33484791 |
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NCBI chr17:23,683,753...23,731,125
Ensembl chr17:23,693,878...23,730,001
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G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in increased expression of MAP1LC3A protein |
CTD |
PMID:35786680 |
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NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions increases lipidation decreases expression |
EXP |
[[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of MAP1LC3B mRNA; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of MAP1LC3B mRNA] Streptozocin results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:35786680 PMID:37352119 PMID:38706688 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map2 |
microtubule-associated protein 2 |
multiple interactions decreases expression |
ISO EXP |
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein] Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein] |
CTD |
PMID:28499986 PMID:38049026 |
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NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:26522834 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
increases expression |
EXP |
Streptozocin results in increased expression of MAP2K6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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G |
Map3k5 |
mitogen-activated protein kinase kinase kinase 5 |
multiple interactions increases expression |
ISO EXP |
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAP3K5 protein]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein] resveratrol inhibits the reaction [Streptozocin results in increased expression of MAP3K5 protein] |
CTD |
PMID:16731828 PMID:26499206 PMID:26522834 |
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NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases activity increases expression increases phosphorylation decreases phosphorylation |
EXP ISO |
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK1 protein] Streptozocin results in increased activity of MAPK1 protein Streptozocin results in increased expression of MAPK1 mRNA; Streptozocin results in increased expression of MAPK1 protein Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK1 protein] 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of and results in decreased phosphorylation of MAPK1 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:12642375 PMID:17063547 PMID:19002579 PMID:19133311 PMID:19682444 PMID:20053369 PMID:20474069 PMID:21300041 PMID:23562514 PMID:25541468 PMID:29059224 PMID:29274332 PMID:30583000 PMID:30607903 PMID:32303808 PMID:33484791 PMID:33631230 PMID:33639173 PMID:34414639 More...
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk10 |
mitogen activated protein kinase 10 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MAPK10 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201
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G |
Mapk11 |
mitogen-activated protein kinase 11 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of MAPK11 protein |
CTD |
PMID:34310909 |
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NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395
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G |
Mapk14 |
mitogen activated protein kinase 14 |
increases phosphorylation multiple interactions |
ISO EXP |
Streptozocin results in increased phosphorylation of MAPK14 protein Atorvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK14 protein] |
CTD |
PMID:15232685 PMID:17589825 |
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NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases activity increases expression multiple interactions increases phosphorylation decreases phosphorylation |
EXP ISO |
Streptozocin results in increased activity of MAPK3 protein Streptozocin results in increased expression of MAPK3 mRNA 1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; baicalin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; capsazepine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Donepezil inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Memantine inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein]; Metformin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; RN 1734 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Streptozocin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased phosphorylation of MAPK3 protein] Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK3 protein] 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK3 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of MAPK3 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:12642375 PMID:19002579 PMID:19133311 PMID:19682444 PMID:20053369 PMID:20474069 PMID:21300041 PMID:23562514 PMID:25541468 PMID:29059224 PMID:29274332 PMID:30583000 PMID:30607903 PMID:32303808 PMID:33484791 PMID:33631230 PMID:33639173 PMID:34414639 More...
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO EXP |
Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK8 protein] [Carnosine co-treated with asiatic acid] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein; asiatic acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Carnosine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK8 protein] [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Ramipril inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:25541468 PMID:26522834 PMID:30802477 PMID:31062909 PMID:33484791 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions increases expression |
EXP ISO |
chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA]]; Hemin inhibits the reaction [Streptozocin results in increased expression of MAPK9 mRNA] Streptozocin inhibits the reaction [AKR1B1 protein results in increased phosphorylation of MAPK9 protein] [Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:19190261 PMID:25541468 PMID:26522834 |
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NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mapkapk2 |
MAPK activated protein kinase 2 |
multiple interactions increases expression |
ISO |
telmisartan inhibits the reaction [Streptozocin results in increased expression of MAPKAPK2 protein modified form] |
CTD |
PMID:21381899 |
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NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
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G |
Mapt |
microtubule-associated protein tau |
increases phosphorylation multiple interactions increases expression |
ISO EXP |
Streptozocin results in increased phosphorylation of MAPT protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form]; Folic Acid inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MAPT protein modified form] Melatonin inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; Melatonin metabolite inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein]; N-acetyl-N-formyl-5-methoxykynurenamine inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] |
CTD |
PMID:20976160 PMID:28422052 PMID:31833155 PMID:34428446 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Mas1 |
MAS1 proto-oncogene, G protein-coupled receptor |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of MAS1 protein CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of MAS1 protein] |
CTD |
PMID:21381899 PMID:29266779 |
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NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
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G |
Mat1a |
methionine adenosyltransferase 1A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] affects the expression of MAT1A mRNA |
CTD |
PMID:29127188 |
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NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274
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G |
Mat2a |
methionine adenosyltransferase 2A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MAT2A mRNA |
CTD |
PMID:29127188 |
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NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
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G |
Mbp |
myelin basic protein |
multiple interactions decreases expression |
EXP |
20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MBP mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of MBP protein] Streptozocin results in decreased expression of MBP mRNA; Streptozocin results in decreased expression of MBP protein |
CTD |
PMID:20349157 PMID:38049026 |
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NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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G |
Mcemp1 |
mast cell-expressed membrane protein 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MCEMP1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986
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G |
Mdh1 |
malate dehydrogenase 1 |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of MDH1 protein] |
CTD |
PMID:21136691 |
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NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925
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G |
Mdh2 |
malate dehydrogenase 2 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of MDH2 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of MDH2 protein] |
CTD |
PMID:19634143 |
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NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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G |
Mecr |
mitochondrial trans-2-enoyl-CoA reductase |
increases expression |
EXP |
Streptozocin results in increased expression of MECR mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
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G |
Mef2c |
myocyte enhancer factor 2C |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of MEF2C mRNA SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA] |
CTD |
PMID:27629361 |
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NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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G |
Mefv |
MEFV innate immunity regulator, pyrin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of MEFV mRNA |
CTD |
PMID:33484791 |
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NCBI chr10:11,786,948...11,796,977
Ensembl chr10:11,787,422...11,796,973
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G |
Mep1a |
meprin A subunit alpha |
multiple interactions |
EXP |
Streptozocin results in decreased activity of and results in decreased expression of MEP1A protein |
CTD |
PMID:15942051 |
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NCBI chr 9:17,474,634...17,504,147
Ensembl chr 9:17,474,619...17,504,147
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G |
Mff |
mitochondrial fission factor |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of MFF mRNA |
CTD |
PMID:33812996 |
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NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
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G |
Mfn2 |
mitofusin 2 |
multiple interactions decreases expression |
EXP ISO |
ferulic acid inhibits the reaction [Streptozocin results in decreased expression of MFN2 protein]; MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; MFN2 protein mutant form inhibits the reaction [Streptozocin results in increased expression of COL4A1 mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA] |
CTD |
PMID:27997345 PMID:31029786 PMID:33812996 |
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NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342
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G |
Mgll |
monoglyceride lipase |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of MGLL mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
decreases response to substance |
ISO |
MGMT protein results in decreased susceptibility to Streptozocin |
CTD |
PMID:16039682 |
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NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
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G |
Mgst2 |
microsomal glutathione S-transferase 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MGST2 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
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G |
Micu1 |
mitochondrial calcium uptake 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MICU1 protein] |
CTD |
PMID:37337224 |
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NCBI chr20:27,668,681...27,816,322
Ensembl chr20:27,668,747...27,814,964
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G |
Mir100 |
microRNA 100 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR100 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
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G |
Mir101-2 |
microRNA 101-2 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR101B mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467
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G |
Mir106a |
microRNA 106a |
increases expression |
ISO |
Streptozocin results in increased expression of MIR106A mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:132,422,584...132,422,661
Ensembl chr X:132,422,584...132,422,661
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Mir10a |
microRNA 10a |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA; HDAC3 protein affects the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of MIR10A mRNA]; MIR10A mRNA affects the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of CREB1 protein] |
CTD |
PMID:27292126 |
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NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
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Mir125b1 |
microRNA 125b-1 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR125B-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
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Mir128-1 |
microRNA 128-1 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR128-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr13:39,699,449...39,699,530
Ensembl chr13:39,699,449...39,699,530
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Mir1306 |
microRNA 1306 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR1306 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:82,709,651...82,709,723
Ensembl chr11:82,709,637...82,709,719
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Mir132 |
microRNA 132 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR132 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:60,023,696...60,023,796
Ensembl chr10:60,023,696...60,023,796
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Mir135a |
microRNA 135a |
increases expression |
ISO |
Streptozocin results in increased expression of MIR135A-2 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:26,611,990...26,612,089
Ensembl chr 7:26,611,990...26,612,089
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Mir135b |
microRNA 135b |
increases expression |
ISO |
Streptozocin results in increased expression of MIR135B mRNA |
CTD |
PMID:27629361 |
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NCBI chr13:43,638,857...43,638,953
Ensembl chr13:43,638,857...43,638,953
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Mir140 |
microRNA 140 |
multiple interactions increases expression |
EXP ISO |
[Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein] streptozocin increases expression of Mir140 RNA in heart |
CTD RGD |
PMID:32062618 PMID:36044268 |
RGD:156430337 |
NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
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Mir142 |
microRNA 142 |
multiple interactions increases expression |
ISO |
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
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Mir144 |
microRNA 144 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MIR144 mRNA SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
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Mir146a |
microRNA 146a |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of MIR146A mRNA Glyburide inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of MIR146A mRNA] |
CTD |
PMID:36504472 |
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NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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Mir146b |
microRNA 146b |
increases expression |
ISO |
Streptozocin results in increased expression of MIR146B mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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Mir152 |
microRNA 152 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of MIR152 mRNA]] |
CTD |
PMID:36547818 |
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NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
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Mir155 |
microRNA 155 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR155 mRNA |
CTD |
PMID:27629361 |
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NCBI chr11:23,774,654...23,774,718
Ensembl chr11:23,774,654...23,774,718
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Mir184 |
microRNA 184 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR184 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 8:90,343,134...90,343,210
Ensembl chr 8:90,343,134...90,343,210
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Mir188 |
microRNA 188 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR188 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:15,247,715...15,247,794
Ensembl chr X:15,247,715...15,247,794
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Mir18a |
microRNA 18a |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR18 mRNA |
CTD |
PMID:27629361 |
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NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
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Mir191 |
microRNA 191 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR191 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 8:109,264,098...109,264,188
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Mir192 |
microRNA 192 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of MIR192 mRNA dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MIR192 mRNA] |
CTD |
PMID:37352119 |
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NCBI chr 1:203,564,946...203,565,055
Ensembl chr 1:203,564,946...203,565,055
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Mir194-1 |
microRNA 194-1 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR194-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr13:96,851,166...96,851,248
Ensembl chr13:96,851,166...96,851,248
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Mir196c |
microRNA 196c |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR196A-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:81,231,006...81,231,085
Ensembl chr10:81,231,006...81,231,085
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Mir200a |
microRNA 200a |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of MIR200A mRNA 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A]; [Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of MIR200A] |
CTD |
PMID:27629361 PMID:37120126 |
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NCBI chr 5:166,648,494...166,648,582
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Mir205 |
microRNA 205 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR205 mRNA |
CTD |
PMID:27629361 |
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NCBI chr13:105,035,878...105,035,985
Ensembl chr13:105,035,878...105,035,985
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Mir20b |
microRNA 20b |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR20B mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282
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Mir21 |
microRNA 21 |
multiple interactions increases expression |
EXP |
dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MIR21 mRNA] |
CTD |
PMID:37352119 |
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NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir216a |
microRNA 216a |
increases expression |
ISO |
Streptozocin results in increased expression of MIR216A mRNA |
CTD |
PMID:27629361 |
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NCBI chr14:102,524,105...102,524,210
Ensembl chr14:102,524,105...102,524,210
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Mir217 |
microRNA 217 |
increases expression decreases expression |
ISO EXP |
Streptozocin results in increased expression of MIR217 mRNA Streptozocin results in decreased expression of MIR217 mRNA |
CTD |
PMID:27629361 PMID:33283391 |
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NCBI chr14:102,531,505...102,531,609
Ensembl chr14:102,531,505...102,531,609
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Mir218-2 |
microRNA 218-2 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR218-2 mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:20,068,451...20,068,560
Ensembl chr10:20,068,451...20,068,560
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Mir219a1 |
microRNA 219a-1 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR219A-1 mRNA |
CTD |
PMID:27629361 |
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NCBI chr20:4,829,687...4,829,796
Ensembl chr20:4,829,687...4,829,796
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Mir222 |
microRNA 222 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR222 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir27a |
microRNA 27a |
multiple interactions decreases expression |
ISO |
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA] |
CTD |
PMID:27629361 |
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NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
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Mir293 |
microRNA 293 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR293 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:65,963,050...65,963,121
Ensembl chr 1:65,963,050...65,963,121
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Mir298 |
microRNA 298 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR298 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 3:163,052,291...163,052,372
Ensembl chr 3:163,052,291...163,052,372
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Mir29a |
microRNA 29a |
multiple interactions decreases expression |
ISO |
MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of CNR1 protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of COL4A2 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL1B protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of IL6 mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of JUN mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] Streptozocin results in decreased expression of MIR29A mRNA |
CTD |
PMID:30642005 |
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NCBI chr 4:59,650,608...59,650,695
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Mir32 |
microRNA 32 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR32 mRNA |
CTD |
PMID:32959695 |
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NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152
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Mir322 |
microRNA 322 |
multiple interactions decreases expression |
ISO |
SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr X:132,806,594...132,806,688
Ensembl chr X:132,806,594...132,806,688
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Mir323 |
microRNA 323 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR323 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:128,725,539...128,725,624
Ensembl chr 6:128,725,539...128,725,624
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Mir33 |
microRNA 33 |
multiple interactions |
EXP |
[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA; Ghrelin inhibits the reaction [[Fructose co-treated with Streptozocin] results in increased expression of MIR33A mRNA] |
CTD |
PMID:31468622 |
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NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923
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Mir330 |
microRNA 330 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR330 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
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Mir3545 |
microRNA 3545 |
affects expression |
ISO |
Streptozocin affects the expression of MIR203 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
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Mir375 |
microRNA 375 |
increases expression |
EXP |
Streptozocin results in increased expression of MIR375 mRNA |
CTD |
PMID:27521901 |
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NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
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Mir377 |
microRNA 377 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR377 |
CTD |
PMID:38282657 |
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NCBI chr 6:128,755,051...128,755,122
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Mir412 |
microRNA 412 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR412 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:128,757,932...128,758,001
Ensembl chr 6:128,757,926...128,758,005
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Mir433 |
microRNA 433 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR433 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:128,545,119...128,545,211
Ensembl chr 6:128,545,112...128,545,217
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Mir448 |
microRNA 448 |
multiple interactions increases expression |
ISO |
SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr X:110,829,918...110,830,029
Ensembl chr X:110,829,918...110,830,029
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Mir451a |
microRNA 451a |
increases expression |
ISO |
Streptozocin results in increased expression of MIR451A mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
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Mir490 |
microRNA 490 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR490 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:65,047,548...65,047,631
Ensembl chr 4:65,047,548...65,047,631
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Mir494 |
microRNA 494 |
multiple interactions |
ISO |
[Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of MIR494 |
CTD |
PMID:38282657 |
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NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
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Mir497 |
microRNA 497 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of MIR497 MIR497 inhibits the reaction [Streptozocin results in decreased expression of MIR497 protein]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein] |
CTD |
PMID:35478295 |
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NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
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Mir499a |
microRNA 499a |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR499 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 3:144,110,469...144,110,533
Ensembl chr 3:144,110,469...144,110,533
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Mir504 |
microRNA 504 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR504 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:137,318,540...137,318,616
Ensembl chr X:137,318,540...137,318,616
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Mir544 |
microRNA 544 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR544 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 6:128,743,530...128,743,607
Ensembl chr 6:128,743,530...128,743,607
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Mir582 |
microRNA 582 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR582 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 2:40,928,571...40,928,651
Ensembl chr 2:40,928,571...40,928,651
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Mir671 |
microRNA 671 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR671 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:10,580,747...10,580,827
Ensembl chr 4:10,580,738...10,580,835
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Mir873 |
microRNA 873 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR873A mRNA |
CTD |
PMID:27629361 |
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NCBI chr 5:51,356,919...51,356,995
Ensembl chr 5:51,356,919...51,356,995
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Mir875 |
microRNA 875 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR875 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 7:66,861,955...66,862,027
Ensembl chr 7:66,861,955...66,862,027
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Mir93 |
microRNA 93 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR93 mRNA |
CTD |
PMID:27629361 |
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NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
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Mir96 |
microRNA 96 |
increases expression |
ISO |
Streptozocin results in increased expression of MIR96 mRNA |
CTD |
PMID:27629361 |
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NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
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Mir98 |
microRNA 98 |
decreases expression |
ISO |
Streptozocin results in decreased expression of MIR98 mRNA |
CTD |
PMID:27629361 |
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NCBI chr X:20,981,235...20,981,342
Ensembl chr X:20,981,235...20,981,342
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Mknk2 |
MAPK interacting serine/threonine kinase 2 |
increases expression |
EXP |
Streptozocin results in increased expression of MKNK2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
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Mme |
membrane metallo-endopeptidase |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of MME protein Trientine inhibits the reaction [Streptozocin results in decreased expression of MME protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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Mmp1 |
matrix metallopeptidase 1 |
increases expression |
EXP |
Streptozocin results in increased expression of MMP1 protein |
CTD |
PMID:35993117 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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Mmp13 |
matrix metallopeptidase 13 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of MMP13 mRNA esculetin inhibits the reaction [Streptozocin results in increased expression of MMP13 mRNA] |
CTD |
PMID:21450970 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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Mmp2 |
matrix metallopeptidase 2 |
multiple interactions increases expression decreases expression increases activity decreases secretion |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA] Streptozocin results in decreased expression of MMP2 mRNA; Streptozocin results in decreased expression of MMP2 protein benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP2 protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA] Streptozocin results in increased expression of MMP2 mRNA; Streptozocin results in increased expression of MMP2 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; CEBPB protein inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein]; ESR2 protein affects the reaction [Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased expression of MMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in decreased secretion of MMP2 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of MMP2 protein] |
CTD |
PMID:16732983 PMID:20446767 PMID:20821936 PMID:23471663 PMID:25246140 PMID:29266779 PMID:29682576 PMID:32662907 PMID:33387473 PMID:37352119 More...
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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Mmp3 |
matrix metallopeptidase 3 |
increases expression multiple interactions decreases expression |
ISO EXP |
Streptozocin results in increased expression of MMP3 mRNA PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA] Streptozocin results in decreased expression of MMP3 mRNA |
CTD |
PMID:18246672 PMID:20446767 |
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NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
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Mmp7 |
matrix metallopeptidase 7 |
multiple interactions increases expression |
ISO |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA] [Streptozocin co-treated with Dietary Fats] results in increased expression of MMP7 mRNA |
CTD |
PMID:20446767 PMID:29127188 |
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NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression increases activity decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA] Streptozocin results in increased expression of MMP9 mRNA; Streptozocin results in increased expression of MMP9 protein [Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of MMP9 protein; idebenone inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Olive Oil inhibits the reaction [Streptozocin results in increased activity of MMP9 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin deficiency results in increased expression of MMP9 mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in decreased expression of MMP9 mRNA] [Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of MMP9 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MMP9 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; Streptozocin promotes the reaction [JUN protein binds to MMP9 promoter]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter] |
CTD |
PMID:19236438 PMID:19820293 PMID:20446767 PMID:22191573 PMID:25246140 PMID:28478229 PMID:28648635 PMID:29682576 PMID:29988851 PMID:30421503 PMID:33387473 PMID:35315182 More...
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mmrn1 |
multimerin 1 |
increases expression |
EXP |
Streptozocin results in increased expression of MMRN1 protein |
CTD |
PMID:21450970 |
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NCBI chr 4:89,875,408...89,950,814
Ensembl chr 4:89,903,174...89,950,474
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G |
Mogat1 |
monoacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MOGAT1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 9:79,980,963...79,988,513
Ensembl chr 9:79,956,649...79,988,513
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Mpg |
N-methylpurine-DNA glycosylase |
affects response to substance |
ISO |
MPG protein affects the susceptibility to Streptozocin |
CTD |
PMID:17098815 |
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NCBI chr10:15,396,246...15,402,528
Ensembl chr10:15,395,782...15,402,520
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Mpo |
myeloperoxidase |
multiple interactions increases activity |
ISO EXP |
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein]]; [Streptozocin co-treated with Dextran Sulfate] results in increased activity of MPO protein; Donepezil inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Lisinopril inhibits the reaction [Streptozocin results in increased activity of MPO protein]; Telmisartan inhibits the reaction [Streptozocin results in increased activity of MPO protein] Streptozocin results in increased expression of and results in increased activity of MPO protein |
CTD |
PMID:23060470 PMID:24924950 PMID:34039237 PMID:34964214 |
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NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819
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Mpped1 |
metallophosphoesterase domain containing 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MPPED1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 7:114,932,221...115,011,797
Ensembl chr 7:114,944,764...115,011,787
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Mpz |
myelin protein zero |
multiple interactions decreases expression |
EXP |
20-alpha-Dihydroprogesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA]; Progesterone inhibits the reaction [Streptozocin results in decreased expression of MPZ mRNA] |
CTD |
PMID:17187935 |
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NCBI chr13:83,570,811...83,576,680
Ensembl chr13:83,570,811...83,576,679
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Mrc1 |
mannose receptor, C type 1 |
multiple interactions decreases expression |
ISO |
AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of MRC1 mRNA]] |
CTD |
PMID:30184259 |
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NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
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Mroh6 |
maestro heat-like repeat family member 6 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of MROH6 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 7:107,566,212...107,576,469
Ensembl chr 7:107,569,554...107,574,173
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Mrpl14 |
mitochondrial ribosomal protein L14 |
affects expression |
ISO |
Streptozocin affects the expression of MRPL14 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 9:15,302,840...15,315,195
Ensembl chr 9:15,302,427...15,315,267
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Mrpl18 |
mitochondrial ribosomal protein L18 |
affects expression |
ISO |
Streptozocin affects the expression of MRPL18 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
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Mrpl42 |
mitochondrial ribosomal protein L42 |
affects expression |
ISO |
Streptozocin affects the expression of MRPL42 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 7:30,117,977...30,141,757
Ensembl chr 7:30,117,977...30,141,639
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Mrps7 |
mitochondrial ribosomal protein S7 |
affects expression |
ISO |
Streptozocin affects the expression of MRPS7 mRNA |
CTD |
PMID:18583417 |
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NCBI chr10:100,843,691...100,846,838
Ensembl chr10:100,843,356...100,847,129
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Ms4a3 |
membrane spanning 4-domains A3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MS4A3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 1:208,462,300...208,480,129
Ensembl chr 1:208,462,301...208,480,101
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Ms4a6a |
membrane spanning 4-domains A6A |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of MS4A6A mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:208,401,465...208,414,831
Ensembl chr 1:208,401,466...208,414,758
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Ms4a6bl1 |
membrane-spanning 4-domains, subfamily A, member 6B-like 1 |
multiple interactions |
EXP |
[Resveratrol co-treated with Streptozocin] results in increased expression of MS4A6BL1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:208,243,561...208,255,400
Ensembl chr 1:208,243,559...208,257,340
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Msln |
mesothelin |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MSLN mRNA |
CTD |
PMID:29127188 |
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NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643
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Mt1 |
metallothionein 1 |
increases expression multiple interactions decreases expression |
EXP |
Streptozocin results in increased expression of MT1A mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MT1A mRNA]; Zinc promotes the reaction [Streptozocin results in increased expression of MT1A mRNA] Streptozocin results in decreased expression of MT1A mRNA |
CTD |
PMID:16684804 PMID:19369054 PMID:24927960 |
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NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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Mt2A |
metallothionein 2A |
decreases expression |
EXP |
Streptozocin results in decreased expression of MT2A mRNA |
CTD |
PMID:24927960 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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Mt3 |
metallothionein 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MT3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
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Mthfr |
methylenetetrahydrofolate reductase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of MTHFR mRNA |
CTD |
PMID:29127188 |
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NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797
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Mtmr7 |
myotubularin related protein 7 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of MTMR7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr16:51,641,267...51,732,212
Ensembl chr16:51,641,190...51,732,182
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Mtor |
mechanistic target of rapamycin kinase |
multiple interactions decreases expression increases expression increases phosphorylation |
EXP ISO |
Resveratrol inhibits the reaction [Streptozocin results in decreased expression of MTOR mRNA]; Streptozocin results in decreased expression of and results in decreased phosphorylation of MTOR protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form]; [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of MTOR protein]; Tadalafil inhibits the reaction [Streptozocin results in increased expression of MTOR protein modified form] streptozocin increases increases phosphorylation of Mtor protein in heart |
CTD RGD |
PMID:26071184 PMID:33484791 PMID:34428446 PMID:38706688 PMID:36044268 |
RGD:156430337 |
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
decreases activity multiple interactions |
EXP ISO |
Streptozocin results in decreased activity of MTR protein [Streptozocin co-treated with Dietary Fats] results in decreased expression of MTR mRNA |
CTD |
PMID:16835399 PMID:29127188 |
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NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
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Myd88 |
MYD88, innate immune signal transduction adaptor |
multiple interactions increases expression |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of MYD88 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of MYD88 mRNA] myrtenol inhibits the reaction [Streptozocin results in increased expression of MYD88 mRNA] |
CTD |
PMID:27769711 PMID:34477272 PMID:34610774 PMID:37482253 |
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NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Myh3 |
myosin heavy chain 3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of MYH3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of MYH3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992
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Myh6 |
myosin heavy chain 6 |
multiple interactions decreases expression |
EXP |
Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Enalapril inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 mRNA]; Losartan inhibits the reaction [Streptozocin results in decreased expression of MYH6 protein] Streptozocin results in decreased expression of MYH6 mRNA; Streptozocin results in decreased expression of MYH6 protein |
CTD |
PMID:15362513 |
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NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
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G |
Myh7 |
myosin heavy chain 7 |
multiple interactions increases expression |
EXP |
Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of MYH7 protein]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 mRNA]; Losartan inhibits the reaction [Streptozocin results in increased expression of MYH7 protein] Streptozocin results in increased expression of MYH7 mRNA; Streptozocin results in increased expression of MYH7 protein |
CTD |
PMID:15362513 |
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NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
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Naglu |
N-acetyl-alpha-glucosaminidase |
increases activity multiple interactions |
EXP |
Streptozocin results in increased activity of NAGLU protein Metformin inhibits the reaction [Streptozocin results in increased activity of NAGLU protein] |
CTD |
PMID:33639173 |
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NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972
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Nampt |
nicotinamide phosphoribosyltransferase |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of NAMPT mRNA [Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NAMPT protein] |
CTD |
PMID:25905778 PMID:29441829 |
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NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100
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Nat8 |
N-acetyltransferase 8 |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of NAT8 mRNA Streptozocin results in increased expression of NAT8 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
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G |
Nat8f3 |
N-acetyltransferase 8 (GCN5-related) family member 3 |
increases expression |
EXP |
Streptozocin results in increased expression of NAT8F3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:118,241,792...118,246,010
Ensembl chr 4:118,239,304...118,285,500
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Ncf1 |
neutrophil cytosolic factor 1 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of NCF1 protein telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; terutroban inhibits the reaction [Streptozocin results in increased expression of NCF1 protein] 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NCF1 protein]; [Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein; Cholesterol, Dietary promotes the reaction [Streptozocin results in increased expression of NCF1 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in increased expression of NCF1 protein] Streptozocin results in increased expression of NCF1 mRNA; Streptozocin results in increased expression of NCF1 protein |
CTD |
PMID:14871415 PMID:16380483 PMID:20399799 PMID:21381899 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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Ncf2 |
neutrophil cytosolic factor 2 |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of NCF2 protein telmisartan inhibits the reaction [Streptozocin results in increased expression of NCF2 protein] [Carbamazepine affects the susceptibility to [Dietary Fats co-treated with Streptozocin]] which results in decreased expression of NCF2 mRNA |
CTD |
PMID:21381899 PMID:35786680 |
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NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277
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Ndst1 |
N-deacetylase and N-sulfotransferase 1 |
multiple interactions decreases expression |
EXP |
Enalapril inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein]; Losartan inhibits the reaction [Streptozocin results in decreased expression of NDST1 protein] Streptozocin results in decreased expression of NDST1 mRNA; Streptozocin results in decreased expression of NDST1 protein |
CTD |
PMID:15793251 |
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NCBI chr18:54,136,887...54,199,545
Ensembl chr18:54,140,779...54,178,191
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Ndufa10 |
NADH:ubiquinone oxidoreductase subunit A10 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of NDUFA10 protein Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFA10 protein] |
CTD |
PMID:21136691 |
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NCBI chr 9:93,007,034...93,041,825
Ensembl chr 9:93,007,042...93,042,560
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Ndufa8 |
NADH:ubiquinone oxidoreductase subunit A8 |
affects expression |
ISO |
Streptozocin affects the expression of NDUFA8 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 3:19,386,062...19,402,090
Ensembl chr 3:19,386,065...19,402,071
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Ndufab1 |
NADH:ubiquinone oxidoreductase subunit AB1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of NDUFAB1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFAB1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:176,644,696...176,658,131
Ensembl chr 1:176,644,703...176,658,099
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Ndufs2 |
NADH:ubiquinone oxidoreductase core subunit S2 |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS2 protein] |
CTD |
PMID:19634143 |
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NCBI chr13:83,654,402...83,671,474
Ensembl chr13:83,654,406...83,671,420
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Ndufs4 |
NADH:ubiquinone oxidoreductase subunit S4 |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFS4 protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846
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G |
Ndufs8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NDUFS8 mRNA] |
CTD |
PMID:37337224 |
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NCBI chr 1:201,140,585...201,144,573
Ensembl chr 1:201,140,585...201,144,511
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Ndufv2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of NDUFV2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of NDUFV2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
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Nefh |
neurofilament heavy chain |
decreases expression |
EXP |
Streptozocin results in decreased expression of NEFH protein |
CTD |
PMID:30583000 |
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NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
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Nes |
nestin |
multiple interactions decreases expression |
ISO EXP |
INS protein inhibits the reaction [Streptozocin results in decreased expression of NES mRNA] Streptozocin results in decreased expression of NES mRNA; Streptozocin results in decreased expression of NES protein |
CTD |
PMID:19388005 |
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NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777
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G |
Neu2 |
neuraminidase 2 |
increases expression |
EXP |
Streptozocin results in increased expression of NEU2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
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Neurod1 |
neuronal differentiation 1 |
multiple interactions decreases expression |
ISO |
[Streptozocin co-treated with bisphenol A] results in decreased expression of NEUROD1 mRNA; octylphenol inhibits the reaction [Streptozocin results in decreased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of NEUROD1 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of NEUROD1 mRNA] |
CTD |
PMID:24781736 PMID:29935216 |
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NCBI chr 3:64,359,554...64,363,526
Ensembl chr 3:64,359,395...64,363,649
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G |
Nfatc1 |
nuclear factor of activated T-cells 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of NFATC1 mRNA; Streptozocin results in increased expression of NFATC1 protein formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 mRNA]; formononetin inhibits the reaction [Streptozocin results in increased expression of NFATC1 protein] |
CTD |
PMID:35315182 |
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NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression affects response to substance decreases expression affects localization increases activity increases expression |
EXP ISO |
2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; 2-tert-butylhydroquinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of NFE2L2 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; dapagliflozin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diallyl trisulfide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; G6PD protein promotes the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of NFE2L2 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD mRNA]; NFE2L2 protein inhibits the reaction [Streptozocin results in decreased expression of G6PD protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; palbinone inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of NFE2L2 protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 mRNA]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of NFE2L2 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; Resveratrol promotes the reaction [Streptozocin affects the localization of NFE2L2 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] Streptozocin results in increased expression of NFE2L2 mRNA; Streptozocin results in increased expression of NFE2L2 protein NFE2L2 protein affects the susceptibility to Streptozocin Streptozocin results in decreased expression of NFE2L2 mRNA; Streptozocin results in decreased expression of NFE2L2 protein 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; [Acrylamide co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of 3-Hydroxybutyric Acid; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Glucose; [NFE2L2 protein mutant form co-treated with Streptozocin] results in increased abundance of Triglycerides; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NFE2L2; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of NFE2L2 protein]; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [Streptozocin results in decreased abundance of Glycogen]; pterostilbene inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein]; pterostilbene inhibits the reaction [Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein; Streptozocin results in decreased phosphorylation of and affects the localization of NFE2L2 protein; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA] Streptozocin results in increased activity of NFE2L2 protein streptozocin increases expression of Nfe2l2 protein in heart |
CTD RGD |
PMID:20086057 PMID:20399799 PMID:21439372 PMID:21799698 PMID:22023613 PMID:22790776 PMID:23319174 PMID:23453443 PMID:24707343 PMID:24740756 PMID:24967692 PMID:25541178 PMID:26700463 PMID:30203046 PMID:30817903 PMID:30927557 PMID:31173751 PMID:31726037 PMID:32202043 PMID:32662907 PMID:33359794 PMID:33639173 PMID:34610774 PMID:34896238 PMID:35442559 PMID:35478295 PMID:36510688 PMID:36999408 PMID:37120126 PMID:37352119 PMID:36044268 More...
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RGD:156430337 |
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
increases activity multiple interactions |
EXP ISO |
Streptozocin results in increased activity of NFKB1 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA; [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NFKB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NFKB1 mRNA] |
CTD |
PMID:15284299 PMID:31100278 PMID:34610774 PMID:36999408 PMID:37054934 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
increases expression multiple interactions decreases expression increases phosphorylation increases degradation |
EXP ISO |
Streptozocin results in increased expression of NFKBIA mRNA; Streptozocin results in increased expression of NFKBIA protein 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]]; arjunolic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of NFKBIA protein]; benazepril inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; chromium histidinate inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NFKBIA mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in decreased expression of NFKBIA protein modified form]; picolinic acid inhibits the reaction [Streptozocin results in decreased expression of NFKBIA protein]; Quercetin inhibits the reaction [Streptozocin results in increased degradation of NFKBIA protein]; Streptozocin promotes the reaction [IGF2R protein modified form results in decreased expression of NFKBIA protein modified form]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of NFKBIA mRNA] Streptozocin results in decreased expression of NFKBIA mRNA; Streptozocin results in decreased expression of NFKBIA protein; Streptozocin results in decreased expression of NFKBIA protein modified form |
CTD |
PMID:15284299 PMID:15976052 PMID:16177186 PMID:16684804 PMID:17900838 PMID:20053369 PMID:22790776 PMID:23376009 PMID:24781736 PMID:29953732 PMID:36462176 More...
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nfkbib |
NFKB inhibitor beta |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFKBIB mRNA; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NFKBIB mRNA] |
CTD |
PMID:34610774 |
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NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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G |
Nfkbiz |
NFKB inhibitor zeta |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of NFKBIZ mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723
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G |
Ngf |
nerve growth factor |
multiple interactions affects localization increases expression decreases expression |
EXP |
4-methylcatechol inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; epalrestat inhibits the reaction [Streptozocin results in decreased expression of NGF protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of NGF mRNA]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of NGF protein] Streptozocin affects the localization of NGF protein |
CTD |
PMID:8195800 PMID:9628756 PMID:9748608 PMID:12031555 PMID:38049026 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nim1k |
NIM1 serine/threonine protein kinase |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of NIM1K mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:51,670,764...51,714,782
Ensembl chr 2:51,670,772...51,714,762
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G |
Nipsnap2 |
nipsnap homolog 2 |
affects expression |
ISO |
Streptozocin affects the expression of NIPSNAP2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr12:26,906,068...26,944,201
Ensembl chr12:26,911,723...26,944,166
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G |
Nkap |
NFKB activating protein |
multiple interactions |
EXP |
Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of NKAP mRNA] |
CTD |
PMID:30611788 |
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NCBI chr X:116,373,031...116,392,677
Ensembl chr X:116,372,839...116,394,945
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions increases expression |
EXP ISO |
[Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; palbinone inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein]; scutellarin inhibits the reaction [Streptozocin results in increased expression of NLRP3 protein] Streptozocin results in increased expression of NLRP3 mRNA; Streptozocin results in increased expression of NLRP3 protein [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NLRP3 protein]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 mRNA]; loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein]; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of CASP1 protein] |
CTD |
PMID:23647015 PMID:27783111 PMID:32202043 PMID:34477272 PMID:35961541 PMID:36999408 PMID:37081038 PMID:37473909 More...
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nmrk1 |
nicotinamide riboside kinase 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of NMRK1 mRNA [resveratrol co-treated with Streptozocin] results in decreased expression of NMRK1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:216,049,350...216,076,792
Ensembl chr 1:216,049,437...216,076,791
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G |
Nnt |
nicotinamide nucleotide transhydrogenase |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of NNT protein] |
CTD |
PMID:19634143 |
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NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823
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G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions decreases expression increases expression |
EXP ISO |
1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; [Sildenafil Citrate co-treated with resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS1 protein] Streptozocin results in decreased expression of NOS1 mRNA; Streptozocin results in decreased expression of NOS1 protein Streptozocin results in increased expression of NOS1 mRNA Acrylamide inhibits the reaction [Streptozocin results in increased expression of NOS1 mRNA] |
CTD |
PMID:18528636 PMID:26006044 PMID:34896238 |
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NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases expression increases activity |
ISO EXP |
[bisphenol A co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Ethinyl Estradiol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [octylphenol co-treated with Streptozocin] results in decreased expression of NOS2 protein; [Streptozocin co-treated with bisphenol A] results in increased expression of NOS2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA; AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in decreased expression of NOS2 mRNA]; Streptozocin inhibits the reaction [octylphenol results in decreased expression of NOS2 mRNA]; terutroban inhibits the reaction [Streptozocin results in increased expression of NOS2 protein] Streptozocin results in increased expression of NOS2 mRNA; Streptozocin results in increased expression of NOS2 protein 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of NOS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Metformin inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Metoprolol inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in increased expression of NOS2 protein]]; Triterpenes inhibits the reaction [Streptozocin results in increased activity of NOS2 protein]; Triterpenes inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA] |
CTD |
PMID:15821039 PMID:16139267 PMID:16177186 PMID:16309587 PMID:16380483 PMID:18528636 PMID:18703049 PMID:18779489 PMID:18789669 PMID:19000375 PMID:19397970 PMID:19957251 PMID:22675305 PMID:25541178 PMID:25635252 PMID:26690102 PMID:26887929 PMID:29935216 PMID:30184259 PMID:33484791 PMID:33639173 PMID:36510688 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions increases expression decreases phosphorylation decreases expression |
EXP |
1,3-dimethoxy-5-methyl-2-(3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl)benzene inhibits the reaction [4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; 1-hexacosanol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; 4-(3-3,4-p-menthadien-(1,8)-yl)olivetol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; [Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]; Atorvastatin inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; Cholesterol, Dietary inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of NOS3 protein]; cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of NOS3 mRNA]; Streptozocin promotes the reaction [CAV1 protein binds to NOS3 protein]; Streptozocin results in decreased activity of and results in decreased phosphorylation of NOS3 protein Streptozocin results in increased expression of NOS3 mRNA; Streptozocin results in increased expression of NOS3 protein Streptozocin results in decreased expression of NOS3 mRNA; Streptozocin results in decreased expression of NOS3 protein |
CTD |
PMID:11696579 PMID:12377873 PMID:14871415 PMID:16045816 PMID:16139267 PMID:17589825 PMID:18266981 PMID:18528636 PMID:18703049 PMID:19279317 PMID:21664865 PMID:21912612 PMID:22191573 PMID:22675305 PMID:26006044 PMID:26071184 PMID:28946194 PMID:29274332 More...
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nox4 |
NADPH oxidase 4 |
multiple interactions increases expression |
EXP ISO |
[Resveratrol co-treated with Streptozocin] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA] [Streptozocin co-treated with Dietary Fats] results in decreased expression of NOX4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NOX4 protein; aucubin inhibits the reaction [Streptozocin results in increased expression of NOX4 protein] |
CTD |
PMID:16979161 PMID:25905778 PMID:29127188 PMID:35085591 PMID:35961541 |
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NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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G |
Npas2 |
neuronal PAS domain protein 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of NPAS2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320
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G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
decreases expression |
EXP ISO |
Streptozotocin decreases expression of Nphs1 mRNA and protein in kidney Streptozotocin decreases expression of Nphs1 mRNA and protein in renal glomerulus Streptozocin decreases expression of Nphs1 mRNA in kidney streptozotocin decreases expression of Nphs1 protein in kidney |
RGD |
PMID:17624267 PMID:30862474 PMID:24173355 PMID:21617141 |
RGD:38596322, RGD:38596325, RGD:38599008, RGD:7241083 |
NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
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G |
Nphs2 |
NPHS2 stomatin family member, podocin |
multiple interactions decreases expression |
EXP ISO |
Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS2 protein] Streptozocin results in decreased expression of NPHS2 mRNA; Streptozocin results in decreased expression of NPHS2 protein AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]; Perindopril inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in decreased expression of NPHS2 protein]] |
CTD |
PMID:20547220 PMID:25199697 PMID:30184259 |
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NCBI chr13:68,448,720...68,461,312
Ensembl chr13:68,448,926...68,461,313
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G |
Nppa |
natriuretic peptide A |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of NPPA mRNA; Streptozocin results in increased expression of NPPA protein SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA] Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of NPPA protein] |
CTD |
PMID:16409969 PMID:16980342 PMID:18945756 |
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NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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G |
Nppb |
natriuretic peptide B |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of NPPB mRNA [Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein; Chlorogenic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Fructose] results in increased expression of NPPB protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of NPPB protein; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NPPB protein] |
CTD |
PMID:10828832 PMID:34610774 PMID:34801538 |
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NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Nppc |
natriuretic peptide C |
decreases expression |
EXP |
Streptozocin results in decreased expression of NPPC mRNA |
CTD |
PMID:10828832 |
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NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
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G |
Npy |
neuropeptide Y |
multiple interactions increases expression |
EXP |
INS protein inhibits the reaction [Streptozocin results in increased expression of NPY mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions decreases expression affects response to substance increases expression |
EXP ISO |
diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA] Streptozocin results in decreased expression of NQO1 mRNA; Streptozocin results in decreased expression of NQO1 protein NQO1 protein affects the susceptibility to Streptozocin Streptozocin results in increased expression of NQO1 mRNA 2,5-dihydroxybenzoic acid promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; [omaveloxolone analog co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [omaveloxolone co-treated with Streptozocin co-treated with Dietary Fats] results in increased activity of NQO1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of AIFM1 protein; [Streptozocin co-treated with NQO1 protein mutant form] results in increased expression of CASP3 protein modified form; [Streptozocin co-treated with NQO1 protein mutant form] results in increased secretion of DIABLO protein; [Streptozocin co-treated with sulforaphane] results in increased expression of NQO1; Metformin promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of NQO1 mRNA]; omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NQO1 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 mRNA]; sulforaphane inhibits the reaction [Streptozocin results in decreased expression of NQO1 protein] |
CTD |
PMID:21457706 PMID:22023613 PMID:22531820 PMID:23319174 PMID:23458895 PMID:24967692 PMID:32410268 PMID:32662907 PMID:33639173 PMID:34610774 PMID:37120126 More...
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions |
EXP ISO |
[resveratrol co-treated with Streptozocin] results in increased expression of NR0B2 mRNA [Dietary Fats co-treated with Streptozocin] results in increased expression of NR0B2 protein |
CTD |
PMID:25905778 PMID:29382564 |
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NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1d1 |
nuclear receptor subfamily 1, group D, member 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of NR1D1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
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G |
Nr1h2 |
nuclear receptor subfamily 1, group H, member 2 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of NR1H2 protein [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H2 mRNA; homocastasterone analog inhibits the reaction [Streptozocin results in decreased expression of NR1H2 protein] |
CTD |
PMID:28822685 |
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NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions increases expression increases expression |
EXP |
[homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 mRNA; [homocastasterone analog co-treated with Streptozocin] results in increased expression of NR1H3 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of NR1H3 protein] Streptozocin results in increased expression of NR1H3 mRNA; Streptozocin results in increased expression of NR1H3 protein Streptozotocin increases expression of Nr1h3 mRNA and protein in the heart |
CTD RGD |
PMID:23647015 PMID:28822685 PMID:21136146 |
RGD:13831298 |
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of NR1H4 protein |
CTD |
PMID:29382564 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nt5e |
5' nucleotidase, ecto |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of NT5E mRNA |
CTD |
PMID:29127188 |
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NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
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G |
Ntf3 |
neurotrophin 3 |
affects localization |
EXP |
Streptozocin affects the localization of NTF3 protein |
CTD |
PMID:12031555 |
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NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596
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G |
Ntn1 |
netrin 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of NTN1 protein [NTN1 protein co-treated with Streptozocin] results in increased expression of ARG1 protein; NTN1 protein inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A mRNA]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN2A protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC mRNA]; NTN1 protein promotes the reaction [Streptozocin results in increased expression of DCC protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK1 protein]; Streptozocin promotes the reaction [NTN1 protein results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:29059224 |
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NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326
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G |
Ntrk1 |
neurotrophic receptor tyrosine kinase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NTRK1 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of NTRK1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
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G |
Ntrk2 |
neurotrophic receptor tyrosine kinase 2 |
decreases phosphorylation multiple interactions decreases expression |
ISO EXP |
Streptozocin results in decreased phosphorylation of NTRK2 protein Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein] Metformin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA]; morin inhibits the reaction [Streptozocin results in increased expression of NTRK2 mRNA] Streptozocin results in decreased expression of NTRK2 mRNA |
CTD |
PMID:28499986 PMID:35414346 |
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NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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G |
Nudt7 |
nudix hydrolase 7 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of NUDT7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr19:42,125,679...42,151,198
Ensembl chr19:42,125,711...42,151,081
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G |
Nus1 |
NUS1 dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of NUS1 protein; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of MFN2 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of GSK3B protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ACACA mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF4 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of ATF6 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of DGAT1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of EIF2AK3 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of FASN mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of GK mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of HSPA5 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of INPP5K mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased phosphorylation of EIF2S1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:33812996 |
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NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
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G |
Nyap1 |
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of NYAP1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr12:18,956,192...18,967,624
Ensembl chr12:18,956,268...18,967,543
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G |
Oat |
ornithine aminotransferase |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of OAT protein Trientine inhibits the reaction [Streptozocin results in decreased expression of OAT protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Ocln |
occludin |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of OCLN protein rhodioloside inhibits the reaction [Streptozocin results in decreased expression of OCLN protein] |
CTD |
PMID:31682803 |
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NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
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G |
Oga |
O-GlcNAcase |
multiple interactions |
ISO EXP |
Streptozocin binds to and results in decreased activity of OGA protein [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of OGA protein] |
CTD |
PMID:18721751 PMID:30551545 |
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NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
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G |
Ogdh |
oxoglutarate dehydrogenase |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of OGDH protein] |
CTD |
PMID:19634143 |
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NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
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G |
Olr59 |
olfactory receptor 59 |
decreases expression |
EXP |
Streptozocin results in decreased expression of OLR59 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
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G |
Opn4 |
opsin 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of OPN4 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr16:9,920,408...9,929,580
Ensembl chr16:9,920,491...10,005,711
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G |
Orm1 |
orosomucoid 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of ORM1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154
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G |
P2rx2 |
purinergic receptor P2X 2 |
increases expression |
ISO |
Streptozocin results in increased expression of P2RX2 mRNA |
CTD |
PMID:19383439 |
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NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891
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G |
P2rx3 |
purinergic receptor P2X 3 |
increases expression |
ISO |
Streptozocin results in increased expression of P2RX3 mRNA |
CTD |
PMID:19383439 |
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NCBI chr 3:70,080,850...70,124,664
Ensembl chr 3:70,080,851...70,125,178
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G |
Pabpc1l |
poly(A) binding protein, cytoplasmic 1-like |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PABPC1L mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:152,692,825...152,725,997
Ensembl chr 3:152,693,700...152,725,997
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G |
Pah |
phenylalanine hydroxylase |
multiple interactions increases activity increases expression |
EXP |
peroxovanadate inhibits the reaction [Streptozocin results in increased activity of PAH protein]; peroxovanadate inhibits the reaction [Streptozocin results in increased expression of PAH mRNA] |
CTD |
PMID:11055810 |
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NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
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G |
Pak1 |
p21 (RAC1) activated kinase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PAK1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
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G |
Parg |
poly (ADP-ribose) glycohydrolase |
increases response to substance |
ISO |
PARG gene mutant form results in increased susceptibility to Streptozocin |
CTD |
PMID:15282315 |
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NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage multiple interactions increases activity |
EXP ISO |
Streptozocin results in increased cleavage of PARP1 protein Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein]; Curcumin inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein] Streptozocin results in increased activity of PARP1 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of PARP1 mRNA; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin results in increased activity of PARP1 protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PARP1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]; Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein] |
CTD |
PMID:25541178 PMID:27288104 PMID:28478229 PMID:28856781 PMID:34610774 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pax8 |
paired box 8 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of PAX8 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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G |
Pc |
pyruvate carboxylase |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of PC protein Trientine inhibits the reaction [Streptozocin results in increased expression of PC protein] [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCX protein |
CTD |
PMID:19634143 PMID:25446853 |
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NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression |
EXP ISO |
bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; cinnamaldehyde inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of PCK1 protein] Streptozocin results in increased expression of PCK1 mRNA; Streptozocin results in increased expression of PCK1 protein [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PCK1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PCK1 mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PCK1 mRNA] |
CTD |
PMID:12446591 PMID:19634143 PMID:20363216 PMID:25446853 PMID:26522834 PMID:34896238 More...
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
multiple interactions increases expression |
EXP |
Tribulus extract inhibits the reaction [Streptozocin results in increased expression of PCK2 protein] |
CTD |
PMID:36627075 |
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NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
EXP ISO |
[Streptozocin co-treated with Tobacco Smoke Pollution] results in increased expression of PCNA protein [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PCNA protein |
CTD |
PMID:30421503 PMID:34964214 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pcsk1 |
proprotein convertase subtilisin/kexin type 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of PCSK1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434
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G |
Pde4b |
phosphodiesterase 4B |
decreases expression |
EXP |
Streptozocin results in decreased expression of PDE4B mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696
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G |
Pde5a |
phosphodiesterase 5A |
multiple interactions increases expression |
EXP |
[Sildenafil Citrate co-treated with Resveratrol] inhibits the reaction [Streptozocin results in increased expression of PDE5A protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PDE5A protein] Streptozocin results in increased expression of PDE5A mRNA; Streptozocin results in increased expression of PDE5A protein |
CTD |
PMID:26006044 |
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NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
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G |
Pde6c |
phosphodiesterase 6C |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PDE6C mRNA |
CTD |
PMID:33484791 |
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NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
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G |
Pdgfra |
platelet derived growth factor receptor alpha |
decreases expression |
ISO |
Streptozocin results in decreased expression of PDGFRA mRNA |
CTD |
PMID:26073000 |
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NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
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G |
Pdgfrl |
platelet-derived growth factor receptor-like |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PDGFRL mRNA] |
CTD |
PMID:33484791 |
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NCBI chr16:51,347,929...51,407,850
Ensembl chr16:51,347,948...51,407,850
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G |
Pdk1 |
pyruvate dehydrogenase kinase 1 |
multiple interactions |
ISO |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of PDK1 mRNA |
CTD |
PMID:25446853 |
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NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038
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G |
Pdx1 |
pancreatic and duodenal homeobox 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of PDX1 mRNA [Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PDX1 protein]; octylphenol inhibits the reaction [Streptozocin results in decreased expression of PDX1 mRNA] |
CTD |
PMID:24781736 PMID:29935216 PMID:33359794 |
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NCBI chr12:7,757,865...7,763,064
Ensembl chr12:7,757,865...7,763,064
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G |
Pdxp |
pyridoxal phosphatase |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of PDXP mRNA Streptozocin results in increased expression of PDXP mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:110,472,515...110,477,963
Ensembl chr 7:110,472,515...110,477,963
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G |
Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PECAM1 protein] |
CTD |
PMID:27097221 |
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NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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G |
Pemt |
phosphatidylethanolamine N-methyltransferase |
increases activity affects expression |
EXP ISO |
Streptozocin results in increased activity of PEMT protein Streptozocin affects the expression of PEMT mRNA |
CTD |
PMID:16835399 PMID:18583417 |
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NCBI chr10:44,775,910...44,849,990
Ensembl chr10:44,775,911...44,850,013
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G |
Pfkfb1 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
increases expression |
EXP |
Streptozocin results in increased expression of PFKFB1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:19,508,522...19,562,165
Ensembl chr X:19,508,546...19,562,182
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G |
Pfkfb2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
multiple interactions decreases activity |
EXP |
Lithium Carbonate inhibits the reaction [Streptozocin results in decreased activity of PFKFB2 protein] |
CTD |
PMID:10700396 |
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NCBI chr13:42,147,473...42,174,699
Ensembl chr13:42,147,478...42,174,699
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G |
Pfkp |
phosphofructokinase, platelet |
multiple interactions |
ISO |
[1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PFKP protein |
CTD |
PMID:25446853 |
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NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018
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G |
Phactr3 |
phosphatase and actin regulator 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PHACTR3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:165,205,247...165,423,692
Ensembl chr 3:165,205,255...165,423,153
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G |
Phb1 |
prohibitin 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of PHB1 protein |
CTD |
PMID:21136691 |
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NCBI chr10:80,605,268...80,618,043
Ensembl chr10:80,605,251...80,618,042
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
multiple interactions |
ISO |
streptozocin decreases expression and increases phosphorylation of Pik3ca in cardiac muscle cells |
RGD |
PMID:36044268 |
RGD:156430337 |
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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G |
Pik3cb |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of PIK3CB mRNA resveratrol inhibits the reaction [Streptozocin results in decreased expression of PIK3CB mRNA] [Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PIK3CB protein]] |
CTD |
PMID:26071184 PMID:29526571 |
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NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
multiple interactions decreases expression |
EXP ISO |
Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in decreased expression of PIK3R1 mRNA]] [Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased phosphorylation of PIK3R1 protein] |
CTD |
PMID:32805344 PMID:33484791 |
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NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of PINK1 mRNA |
CTD |
PMID:33812996 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Pitpnc1 |
phosphatidylinositol transfer protein, cytoplasmic 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PITPNC1 mRNA |
CTD |
PMID:20665664 |
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NCBI chr10:92,163,558...92,428,971
Ensembl chr10:92,167,196...92,429,297
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G |
Pklr |
pyruvate kinase L/R |
multiple interactions decreases expression |
EXP ISO |
cinnamaldehyde inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PKLR mRNA] [1-Deoxynojirimycin co-treated with Polysaccharides] inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PKLR protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PKLR mRNA] |
CTD |
PMID:20363216 PMID:25446853 PMID:26522834 |
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NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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G |
Pkm |
pyruvate kinase M1/2 |
affects expression |
ISO |
Streptozocin affects the expression of PKM mRNA |
CTD |
PMID:18583417 |
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NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599
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G |
Pla2g7 |
phospholipase A2 group VII |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PLA2G7 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 9:17,362,214...17,404,476
Ensembl chr 9:17,362,225...17,404,476
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G |
Plaat3 |
phospholipase A and acyltransferase 3 |
multiple interactions |
EXP |
[Resveratrol co-treated with Streptozocin] results in increased expression of PLAAT3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:204,782,608...204,816,397
Ensembl chr 1:204,782,729...204,817,667
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G |
Plau |
plasminogen activator, urokinase |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of PLAU mRNA; Streptozocin results in increased expression of PLAU protein [resveratrol co-treated with Streptozocin] results in increased expression of PLAU mRNA; benazepril inhibits the reaction [Streptozocin results in increased expression of PLAU mRNA] |
CTD |
PMID:15322501 PMID:25905778 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Plaur |
plasminogen activator, urokinase receptor |
increases expression multiple interactions |
EXP ISO |
Streptozocin results in increased expression of PLAUR mRNA; Streptozocin results in increased expression of PLAUR protein benazepril inhibits the reaction [Streptozocin results in increased expression of PLAUR mRNA] [Streptozocin co-treated with Dietary Fats] results in increased expression of PLAUR mRNA |
CTD |
PMID:15322501 PMID:29127188 |
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NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595
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G |
Plcb1 |
phospholipase C beta 1 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB1 protein] |
CTD |
PMID:20691780 |
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NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869
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G |
Plcb2 |
phospholipase C, beta 2 |
multiple interactions increases expression |
EXP |
acetovanillone inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein]; CAT protein inhibits the reaction [Streptozocin results in increased expression of PLCB2 protein] |
CTD |
PMID:20691780 |
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NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302
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G |
Plch1 |
phospholipase C, eta 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PLCH1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 2:148,148,908...148,363,616
Ensembl chr 2:148,148,921...148,364,097
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G |
Plin2 |
perilipin 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of PLIN2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Pln |
phospholamban |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of PLN mRNA; Streptozocin results in decreased expression of PLN protein Triterpenes inhibits the reaction [Streptozocin results in decreased expression of PLN mRNA]; Triterpenes inhibits the reaction [Streptozocin results in decreased expression of PLN protein] |
CTD |
PMID:19000375 |
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NCBI chr20:32,629,537...32,639,559
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G |
Plscr1 |
phospholipid scramblase 1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of PLSCR1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
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G |
Pmp22 |
peripheral myelin protein 22 |
multiple interactions decreases expression |
EXP |
Progesterone inhibits the reaction [Streptozocin results in decreased expression of PMP22 mRNA] |
CTD |
PMID:17187935 |
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NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
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G |
Pnpt1 |
polyribonucleotide nucleotidyltransferase 1 |
affects expression |
ISO |
Streptozocin affects the expression of PNPT1 mRNA |
CTD |
PMID:18583417 |
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NCBI chr14:102,877,553...102,908,696
Ensembl chr14:102,877,553...102,908,696
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G |
Polg |
DNA polymerase gamma, catalytic subunit |
affects expression |
ISO |
Streptozocin affects the expression of POLG mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:133,382,764...133,399,578
Ensembl chr 1:133,382,766...133,398,567
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G |
Polg2 |
DNA polymerase gamma 2, accessory subunit |
affects expression |
ISO |
Streptozocin affects the expression of POLG2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008
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G |
Pomc |
proopiomelanocortin |
multiple interactions decreases expression |
EXP |
INS protein inhibits the reaction [Streptozocin results in decreased expression of POMC mRNA] |
CTD |
PMID:20219977 |
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NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases expression decreases activity |
EXP |
[Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 mRNA; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in decreased expression of PON1 protein; [Propolis co-treated with Streptozocin] results in decreased expression of PON1 protein; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in increased expression of PON1 protein]; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA; [Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein; Chlorpyrifos inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Chlorpyrifos promotes the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in decreased expression of PON1 protein]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 mRNA]; Propolis inhibits the reaction [Streptozocin results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Chlorpyrifos results in decreased expression of PON1 protein]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 mRNA]; Streptozocin inhibits the reaction [Propolis results in increased expression of PON1 protein]; Streptozocin promotes the reaction [Chlorpyrifos results in decreased expression of PON1 mRNA] Streptozocin results in decreased expression of PON1 mRNA; Streptozocin results in decreased expression of PON1 protein Streptozocin results in decreased activity of PON1 protein |
CTD |
PMID:31400774 PMID:34039237 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Por |
cytochrome p450 oxidoreductase |
increases expression |
EXP |
Streptozocin results in increased expression of POR mRNA |
CTD |
PMID:25905778 |
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NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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G |
Pou1f1 |
POU class 1 homeobox 1 |
increases expression multiple interactions |
ISO |
Streptozocin results in increased expression of POU1F1 mRNA; Streptozocin results in increased expression of POU1F1 protein INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of POU1F1 protein] |
CTD |
PMID:29216956 |
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NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
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G |
Pou5f1 |
POU class 5 homeobox 1 |
multiple interactions |
EXP |
[bisphenol A co-treated with Streptozocin] results in decreased expression of POU5F1 protein |
CTD |
PMID:35187753 |
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NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
affects response to substance multiple interactions decreases expression increases expression |
ISO EXP |
PPARA protein affects the susceptibility to Streptozocin [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of PPARA mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Metformin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARA protein]; puerarin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA] [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein; [Streptozocin co-treated with Cadmium] results in decreased expression of PPARA protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Allopurinol inhibits the reaction [Streptozocin results in decreased expression of PPARA protein]; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARA protein]; idebenone inhibits the reaction [Streptozocin results in increased expression of PPARA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARA protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA mRNA]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of PPARA protein] Streptozocin results in decreased expression of PPARA mRNA; Streptozocin results in decreased expression of PPARA protein |
CTD |
PMID:12967931 PMID:16306367 PMID:18338635 PMID:23647015 PMID:23927877 PMID:25240712 PMID:25246140 PMID:28648635 PMID:29614383 PMID:29988851 PMID:31063766 PMID:34896238 PMID:35786680 More...
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
decreases expression multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of PPARD mRNA [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]; Fenofibrate inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in increased expression of PPARD protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARD mRNA] [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARB protein] |
CTD |
PMID:18338635 PMID:25246140 PMID:31063766 |
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions decreases expression increases expression |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of PPARG mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; MIR29A mRNA inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Carboxymethylcellulose Sodium] results in decreased expression of PPARG protein]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARG protein] Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein Streptozocin results in increased expression of PPARG mRNA; Streptozocin results in increased expression of PPARG protein 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]]; 2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein; [Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein; allyl isothiocyanate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; Berberine inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein]; Bezafibrate inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of PPARG protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Hesperidin inhibits the reaction [2-chloro-5-nitrobenzanilide promotes the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]]; Hesperidin inhibits the reaction [[Streptozocin co-treated with Isoproterenol] affects the expression of PPARG protein]; INS protein promotes the reaction [Streptozocin results in increased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Carbohydrates] results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG] Streptozocin results in decreased expression of PPARG; Streptozocin results in decreased expression of PPARG mRNA; Streptozocin results in decreased expression of PPARG protein |
CTD |
PMID:12967931 PMID:16980342 PMID:18338635 PMID:20219977 PMID:21381899 PMID:21450970 PMID:23319174 PMID:24136780 PMID:24954035 PMID:25246140 PMID:27350165 PMID:27769711 PMID:29223569 PMID:29953732 PMID:30642005 PMID:30927557 PMID:31063766 PMID:33359794 PMID:33484791 PMID:34175429 PMID:34470562 PMID:37044004 PMID:37566541 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
decreases expression multiple interactions increases expression |
ISO EXP |
Streptozocin results in decreased expression of PPARGC1A protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PPARGC1A mRNA]; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPARGC1A mRNA]; Telmisartan inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARGC1A protein] Streptozocin results in increased expression of PPARGC1A mRNA Streptozocin results in decreased expression of PPARGC1A mRNA; Streptozocin results in decreased expression of PPARGC1A protein ferulic acid inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; Olive Oil inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A mRNA]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein] |
CTD |
PMID:21381899 PMID:23319174 PMID:25246140 PMID:26522834 PMID:31029786 PMID:33812996 PMID:35442559 PMID:37337224 More...
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Ppfia3 |
PTPRF interacting protein alpha 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PPFIA3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 1:95,817,110...95,845,950
Ensembl chr 1:95,817,110...95,845,798
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G |
Ppid |
peptidylprolyl isomerase D |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of PPID protein Phosphocreatine inhibits the reaction [Streptozocin results in increased expression of PPID protein] |
CTD |
PMID:34455488 |
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NCBI chr 2:164,727,803...164,740,168
Ensembl chr 2:164,727,779...164,740,221
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G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased phosphorylation of PPP1R12A protein; Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form]; fasudil inhibits the reaction [Streptozocin results in increased expression of PPP1R12A protein modified form] |
CTD |
PMID:20665664 PMID:22429817 |
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NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
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G |
Ppp1r3c |
protein phosphatase 1, regulatory subunit 3C |
decreases expression |
EXP |
Streptozocin results in decreased expression of PPP1R3C mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
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G |
Ppp2ca |
protein phosphatase 2 catalytic subunit alpha |
multiple interactions decreases methylation decreases expression |
ISO |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form]; Folic Acid deficiency promotes the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Folic Acid inhibits the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; INS1 protein affects the reaction [Streptozocin results in decreased methylation of PPP2CA protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PPP2CA protein modified form] |
CTD |
PMID:28422052 PMID:34428446 |
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NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
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G |
Ppy |
pancreatic polypeptide |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PPY mRNA |
CTD |
PMID:33484791 |
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NCBI chr10:87,054,747...87,056,044
Ensembl chr10:87,054,756...87,055,455
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G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions decreases expression |
ISO |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856
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G |
Prdx2 |
peroxiredoxin 2 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of PRDX2 mRNA PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
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G |
Prdx3 |
peroxiredoxin 3 |
multiple interactions decreases expression |
ISO |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111
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G |
Prdx4 |
peroxiredoxin 4 |
multiple interactions decreases expression |
ISO |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX1 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX4 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of IL1B mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP2 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP3 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP7 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of MMP9 mRNA]; PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] [Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of PRDX4 mRNA] |
CTD |
PMID:20446767 PMID:33359794 |
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NCBI chr X:40,026,762...40,044,066
Ensembl chr X:40,026,651...40,044,066
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G |
Prdx5 |
peroxiredoxin 5 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of PRDX5 mRNA PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX5 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
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G |
Prdx6 |
peroxiredoxin 6 |
multiple interactions decreases expression |
ISO |
PRDX4 protein inhibits the reaction [Streptozocin results in decreased expression of PRDX6 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
EXP ISO |
Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein] [Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA1 mRNA] |
CTD |
PMID:35442559 PMID:37337224 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
EXP ISO |
streptozocin decreases expression and phosphorylation of Prkaa2 protein in liver [Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PRKAA2 mRNA] |
CTD RGD |
PMID:37337224 PMID:32535406 |
RGD:401850547 |
NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkaca |
protein kinase cAMP-activated catalytic subunit alpha |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased phosphorylation of PRKACA protein] |
CTD |
PMID:32303808 |
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NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
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G |
Prkca |
protein kinase C, alpha |
multiple interactions increases expression |
EXP |
Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of PRKCA protein] |
CTD |
PMID:12198386 PMID:25199697 |
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NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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G |
Prkcb |
protein kinase C, beta |
increases phosphorylation |
EXP |
Streptozocin results in increased phosphorylation of PRKCB protein |
CTD |
PMID:16980342 |
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NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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G |
Prkcd |
protein kinase C, delta |
multiple interactions increases expression |
EXP |
arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCD protein] |
CTD |
PMID:12198386 PMID:19682444 |
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NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
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G |
Prkce |
protein kinase C, epsilon |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of PRKCE protein; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of PRKCE protein]; Ethanol inhibits the reaction [Streptozocin results in increased expression of PRKCE protein] |
CTD |
PMID:12198386 PMID:19682444 PMID:20665664 |
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NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
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G |
Prkg1 |
protein kinase cGMP-dependent 1 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of PRKG1 protein 5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of PRKG1 protein] |
CTD |
PMID:34428446 |
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NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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G |
Prkg2 |
protein kinase cGMP-dependent 2 |
multiple interactions |
ISO |
[ALPK1 protein results in increased susceptibility to Streptozocin] which results in decreased expression of PRKG2 mRNA |
CTD |
PMID:27542954 |
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NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888
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G |
Prok1 |
prokineticin 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PROK1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:194,850,539...194,859,343
Ensembl chr 2:194,853,991...194,859,250
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G |
Prok2 |
prokineticin 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PROK2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
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G |
Prph |
peripherin |
decreases expression |
EXP |
Streptozocin results in decreased expression of PRPH protein |
CTD |
PMID:30583000 |
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NCBI chr 7:130,218,149...130,222,136
Ensembl chr 7:130,218,357...130,222,136
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G |
Prss1 |
serine protease 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRSS1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792
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G |
Prtn3 |
proteinase 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of PRTN3 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
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G |
Psd2 |
pleckstrin and Sec7 domain containing 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PSD2 mRNA |
CTD |
PMID:33484791 |
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NCBI chr18:27,564,912...27,616,674
Ensembl chr18:27,565,587...27,616,672
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G |
Psrc1 |
proline and serine rich coiled-coil 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of PSRC1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 2:196,022,361...196,026,874
Ensembl chr 2:196,022,361...196,026,874
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G |
Pten |
phosphatase and tensin homolog |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of PTEN mRNA; Streptozocin results in increased expression of PTEN protein Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of PTEN mRNA]] |
CTD |
PMID:32805344 PMID:38706688 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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G |
Ptgs1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions increases expression |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of PTGS1 mRNA; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS1 protein] |
CTD |
PMID:12888618 PMID:18414395 PMID:25905778 |
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NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases activity |
EXP ISO |
[1-((4-methylsulfonyl)phenyl)-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA; [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide binds to and results in decreased activity of PTGS2 protein] which results in decreased susceptibility to Streptozocin; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; acetovanillone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of PTGS2 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Kangen-karyu inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA]; Rosiglitazone inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of PTGS2 mRNA] Streptozocin results in increased expression of PTGS2 mRNA; Streptozocin results in increased expression of PTGS2 protein Acrylamide promotes the reaction [Streptozocin results in increased expression of PTGS2 protein]; asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; Carnosine inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased activity of PTGS2 protein]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein] |
CTD |
PMID:12888618 PMID:14514642 PMID:17112505 PMID:18414395 PMID:19397970 PMID:20223228 PMID:21791967 PMID:25191525 PMID:29059224 PMID:30802477 PMID:30817903 PMID:31009641 PMID:34896238 PMID:36462176 PMID:36510688 PMID:37081038 More...
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptpn1 |
protein tyrosine phosphatase, non-receptor type 1 |
multiple interactions increases expression |
ISO |
resveratrol inhibits the reaction [Streptozocin results in increased expression of PTPN1 protein] |
CTD |
PMID:25808216 |
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NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504
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G |
Ptprd |
protein tyrosine phosphatase, receptor type, D |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRD mRNA |
CTD |
PMID:20665664 |
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NCBI chr 5:90,046,993...90,698,977 NCBI chr 5:91,122,354...91,641,754
Ensembl chr 5:90,048,966...92,369,396
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G |
Ptprm |
protein tyrosine phosphatase, receptor type, M |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRM mRNA |
CTD |
PMID:20665664 |
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NCBI chr 9:106,639,573...107,343,698
Ensembl chr 9:106,639,573...107,343,698
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G |
Ptprt |
protein tyrosine phosphatase, receptor type, T |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of PTPRT mRNA |
CTD |
PMID:20665664 |
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NCBI chr 3:150,189,343...151,288,145
Ensembl chr 3:150,194,859...151,288,124
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G |
Pycard |
PYD and CARD domain containing |
multiple interactions increases expression |
EXP ISO |
Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; palbinone inhibits the reaction [Streptozocin results in increased expression of PYCARD protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of PYCARD protein] Streptozocin results in increased expression of PYCARD mRNA; Streptozocin results in increased expression of PYCARD protein [Streptozocin co-treated with Dextran Sulfate] results in increased expression of PYCARD protein |
CTD |
PMID:23647015 PMID:32202043 PMID:34964214 |
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NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Pygl |
glycogen phosphorylase L |
multiple interactions decreases expression |
EXP |
[Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] affects the activity of PYGL protein] Streptozocin results in decreased expression of PYGL mRNA |
CTD |
PMID:19059388 PMID:25905778 |
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NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
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G |
Pygm |
glycogen phosphorylase, muscle associated |
multiple interactions decreases activity |
EXP |
Plant Extracts inhibits the reaction [Streptozocin results in decreased activity of PYGM protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased activity of PYGM protein] |
CTD |
PMID:26616445 |
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NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
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G |
Pyroxd2 |
pyridine nucleotide-disulphide oxidoreductase domain 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of PYROXD2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of PYROXD2 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:241,523,278...241,549,083
Ensembl chr 1:241,523,377...241,548,761
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G |
Pyy |
peptide YY |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of PYY mRNA |
CTD |
PMID:33484791 |
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NCBI chr10:87,061,155...87,062,278
Ensembl chr10:87,061,161...87,061,815
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions increases activity |
ISO EXP |
Atorvastatin inhibits the reaction [Streptozocin results in increased activity of and results in increased localization of RAC1 protein]; Streptozocin results in increased activity of and results in increased localization of RAC1 protein Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RAC1 protein] |
CTD |
PMID:17279352 PMID:17589825 |
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NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Rac2 |
Rac family small GTPase 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of RAC2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
multiple interactions increases expression decreases expression |
EXP |
manumycin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of RAF1 protein]; xanthoceraside inhibits the reaction [Streptozocin results in decreased expression of RAF1 protein] |
CTD |
PMID:18569938 PMID:23562514 |
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NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Rasgrf1 |
RAS protein-specific guanine nucleotide-releasing factor 1 |
affects localization |
EXP |
Streptozocin affects the localization of RASGRF1 protein |
CTD |
PMID:19002579 |
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NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269
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G |
Rasgrp2 |
RAS guanyl releasing protein 2 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of RASGRP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993
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G |
Rbm39 |
RNA binding motif protein 39 |
decreases expression |
EXP |
Streptozocin results in decreased expression of RBM39 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:144,662,998...144,696,222
Ensembl chr 3:144,663,001...144,696,213
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G |
Rbp4 |
retinol binding protein 4 |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased secretion of RBP4 protein] |
CTD |
PMID:19080170 |
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NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
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G |
Rbpjl |
recombination signal binding protein for immunoglobulin kappa J region-like |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of RBPJL mRNA |
CTD |
PMID:33484791 |
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NCBI chr 3:153,134,044...153,147,421
Ensembl chr 3:153,134,140...153,146,513
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G |
Rdh16 |
retinol dehydrogenase 16 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of RDH2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:63,616,711...63,625,053
Ensembl chr 7:63,597,536...63,624,124
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G |
Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
Streptozocin affects the localization of and results in increased activity of REL protein |
CTD |
PMID:19002579 |
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NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases expression increases phosphorylation affects localization increases activity increases localization |
ISO EXP |
TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA] Streptozocin results in increased expression of RELA mRNA; Streptozocin results in increased expression of RELA protein; Streptozocin results in increased expression of RELA protein modified form Streptozocin results in increased phosphorylation of RELA protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; 5-Methoxypsoralen inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form]; [Streptozocin co-treated with Dextran Sulfate] results in increased phosphorylation of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; EPHX2 gene mutant form inhibits the reaction [Streptozocin results in increased activity of RELA protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased phosphorylation of RELA protein]; montelukast inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; Streptozocin promotes the reaction [RELA protein binds to MMP9 promoter]; Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased phosphorylation of and results in increased activity of RELA protein; Tadalafil inhibits the reaction [Streptozocin results in increased expression of RELA protein modified form] 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein; [Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein; [Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; AC3056 inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Angiotensin Receptor Antagonists inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of RELA protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Curcumin inhibits the reaction [Streptozocin affects the localization of RELA protein]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of and affects the localization of RELA protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of RELA protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Hemin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of RELA protein modified form]; mangiferin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; nifuroxazide inhibits the reaction [Streptozocin results in increased localization of RELA protein]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased activity of RELA protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of RELA protein]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Streptozocin affects the localization of and results in decreased activity of RELA protein; Streptozocin promotes the reaction [IGF2R protein modified form results in increased expression of RELA protein modified form]; Streptozocin results in increased expression of and affects the localization of RELA protein; Streptozocin results in increased expression of and results in decreased phosphorylation of RELA protein; Streptozocin results in increased expression of and results in increased phosphorylation of RELA protein; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of RELA protein]]; Zinc inhibits the reaction [Streptozocin results in increased expression of RELA mRNA] |
CTD |
PMID:17900838 PMID:19002579 PMID:19040617 PMID:19123331 PMID:19133311 PMID:19190261 PMID:19682444 PMID:20053369 PMID:20223228 PMID:20307516 PMID:20424485 PMID:20446767 PMID:20643114 PMID:21439372 PMID:21832210 PMID:22058332 PMID:23376009 PMID:23406761 PMID:23611540 PMID:24740756 PMID:24877639 PMID:25541178 PMID:26341651 PMID:27702591 PMID:28478229 PMID:29059224 PMID:29409856 PMID:29606028 PMID:29953732 PMID:30802477 PMID:31009641 PMID:31323227 PMID:31726037 PMID:32805344 PMID:33724628 PMID:34428446 PMID:34610774 PMID:34964214 PMID:35305976 PMID:35442559 PMID:36462176 PMID:36504472 PMID:36510688 PMID:37044004 PMID:37120126 PMID:37482253 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Retn |
resistin |
multiple interactions increases expression |
EXP |
resveratrol inhibits the reaction [Streptozocin results in increased expression of RETN protein] |
CTD |
PMID:26071184 |
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NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
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G |
Rhbdf2 |
rhomboid 5 homolog 2 |
multiple interactions increases expression |
EXP |
Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of RHBDF2 protein] Streptozocin results in increased expression of RHBDF2 mRNA; Streptozocin results in increased expression of RHBDF2 protein |
CTD |
PMID:35305976 |
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NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283
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G |
Rhoa |
ras homolog family member A |
multiple interactions increases activity increases expression |
EXP |
[Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of RHOA protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased activity of RHOA protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of RHOA protein] |
CTD |
PMID:17589825 PMID:23376009 PMID:31062909 |
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NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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G |
Rnf2 |
ring finger protein 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of RNF2 mRNA |
CTD |
PMID:28946194 |
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NCBI chr13:63,553,964...63,584,047
Ensembl chr13:63,554,862...63,583,099
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G |
Rock1 |
Rho-associated coiled-coil containing protein kinase 1 |
multiple interactions increases expression increases activity |
EXP |
fasudil inhibits the reaction [Streptozocin results in increased activity of ROCK1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of ROCK1 mRNA] Streptozocin results in increased expression of ROCK1 mRNA; Streptozocin results in increased expression of ROCK1 protein |
CTD |
PMID:22429817 PMID:23376009 PMID:31062909 |
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NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
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G |
Rock2 |
Rho-associated coiled-coil containing protein kinase 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ROCK2 protein [Resveratrol co-treated with Ramipril] inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Ramipril inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of ROCK2 protein] |
CTD |
PMID:31062909 |
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NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
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G |
Rpl18a |
ribosomal protein L18A |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of RPL18A mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPL18A mRNA] |
CTD |
PMID:16684804 |
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NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546
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G |
Rprm |
reprimo, TP53 dependent G2 arrest mediator homolog |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of RPRM mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:38,539,581...38,540,998
Ensembl chr 3:38,539,581...38,540,998
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G |
Rps3 |
ribosomal protein S3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of RPS3 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RPS3 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680
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G |
Rrad |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of RRAD mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of RRAD mRNA] |
CTD |
PMID:16684804 |
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NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
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G |
RT1-DMa |
RT1 class II, locus DMa |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMA mRNA |
CTD |
PMID:25905778 |
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NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
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G |
RT1-DMb |
RT1 class II, locus DMb |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of RT1-DMB mRNA |
CTD |
PMID:25905778 |
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NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
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G |
Runx2 |
RUNX family transcription factor 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of RUNX2 mRNA |
CTD |
PMID:25617479 |
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NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
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G |
Rwdd2a |
RWD domain containing 2A |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of RWDD2A mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 8:87,536,153...87,539,301
Ensembl chr 8:87,536,176...87,539,300
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G |
Ryr2 |
ryanodine receptor 2 |
decreases activity multiple interactions decreases expression |
EXP ISO |
Streptozocin results in decreased activity of RYR2 protein [octylphenol co-treated with Streptozocin] results in increased expression of RYR2 mRNA Streptozocin results in decreased expression of RYR2 mRNA Triterpenes inhibits the reaction [Streptozocin results in decreased expression of RYR2 mRNA] |
CTD |
PMID:16685413 PMID:19000375 PMID:29935216 |
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NCBI chr17:58,389,925...58,975,641
Ensembl chr17:58,389,925...58,975,142
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G |
S100a6 |
S100 calcium binding protein A6 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of S100A6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
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G |
S100a8 |
S100 calcium binding protein A8 |
multiple interactions increases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of S100A8 mRNA; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Streptozocin results in increased expression of S100A8 mRNA] |
CTD |
PMID:19833897 PMID:29127188 |
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NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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G |
S100a9 |
S100 calcium binding protein A9 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of S100A9 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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G |
S100b |
S100 calcium binding protein B |
multiple interactions increases expression decreases expression |
EXP |
pimagedine inhibits the reaction [Streptozocin results in decreased expression of S100B protein]; pimagedine inhibits the reaction [Streptozocin results in increased expression of S100B protein] |
CTD |
PMID:19494442 PMID:20953641 |
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NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743
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G |
S1pr2 |
sphingosine-1-phosphate receptor 2 |
increases expression |
EXP |
Streptozocin results in increased expression of S1PR2 mRNA |
CTD |
PMID:22406263 |
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NCBI chr 8:19,503,276...19,514,169
Ensembl chr 8:19,502,627...19,523,574
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G |
S1pr4 |
sphingosine-1-phosphate receptor 4 |
increases expression |
EXP |
Streptozocin results in increased expression of S1PR4 mRNA |
CTD |
PMID:22406263 |
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NCBI chr 7:8,207,767...8,210,043
Ensembl chr 7:8,208,098...8,211,893
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G |
S1pr5 |
sphingosine-1-phosphate receptor 5 |
increases expression |
EXP |
Streptozocin results in increased expression of S1PR5 mRNA |
CTD |
PMID:22406263 |
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NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795
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G |
Scara5 |
scavenger receptor class A, member 5 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SCARA5 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr15:39,880,017...39,985,007
Ensembl chr15:39,880,035...39,983,373
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions increases expression increases expression |
ISO EXP |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SCD1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SCD1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SCD1 mRNA] [[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SCD1 mRNA; [Dietary Fats affects the susceptibility to Streptozocin] which results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SCD1 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SCD1 mRNA streptozocin increases expression of Scd protein in liver |
CTD RGD |
PMID:29127188 PMID:29988851 PMID:34896238 PMID:35786680 PMID:32535406 |
RGD:401850547 |
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Sdha |
succinate dehydrogenase complex flavoprotein subunit A |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of SDHA protein Trientine inhibits the reaction [Streptozocin results in increased expression of SDHA protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 1:28,935,965...28,960,936
Ensembl chr 1:28,940,164...28,961,535
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Sdhb |
succinate dehydrogenase complex iron sulfur subunit B |
multiple interactions increases expression |
EXP ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of SDHB protein] [Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SDHB mRNA] |
CTD |
PMID:19634143 PMID:37337224 |
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NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293
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Sds |
serine dehydratase |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of SDS mRNA |
CTD |
PMID:25905778 |
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NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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Selenop |
selenoprotein P |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA; Sodium Selenite promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SELENOP mRNA] |
CTD |
PMID:26522834 |
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NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852
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Selp |
selectin P |
multiple interactions |
EXP |
[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of SELP protein]] |
CTD |
PMID:36547818 |
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NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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Serpina4 |
serpin family A member 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SERPINA4-PS1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
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Serpina6 |
serpin family A member 6 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of SERPINA6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349
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Serpina7 |
serpin family A member 7 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of SERPINA7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr X:102,663,242...102,722,319
Ensembl chr X:102,663,405...102,669,040
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Serpine1 |
serpin family E member 1 |
multiple interactions increases expression |
ISO EXP |
SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; Streptozocin promotes the reaction [MAP3K5 protein results in increased expression of SERPINE1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein Streptozocin results in increased expression of SERPINE1; Streptozocin results in increased expression of SERPINE1 mRNA; Streptozocin results in increased expression of SERPINE1 protein |
CTD |
PMID:15322501 PMID:16731828 PMID:16973718 PMID:19369054 PMID:21778425 PMID:22744176 PMID:24967692 More...
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpine2 |
serpin family E member 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SERPINE2 protein] |
CTD |
PMID:27097221 |
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NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Serpinh1 |
serpin family H member 1 |
increases expression |
EXP |
Streptozocin results in increased expression of SERPINH1 protein |
CTD |
PMID:12197670 |
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NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
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Setd7 |
SET domain containing 7, histone lysine methyltransferase |
multiple interactions |
EXP |
Streptozocin promotes the reaction [SETD7 protein binds to CDKN1A promoter] |
CTD |
PMID:27652271 |
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NCBI chr 2:135,562,683...135,605,468
Ensembl chr 2:135,562,683...135,605,468
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Sfxn1 |
sideroflexin 1 |
multiple interactions increases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in increased expression of SFXN1 protein] |
CTD |
PMID:19634143 |
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NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
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Sgk1 |
serum/glucocorticoid regulated kinase 1 |
increases expression |
ISO |
Streptozocin results in increased expression of SGK1 mRNA; Streptozocin results in increased expression of SGK1 protein |
CTD |
PMID:16116964 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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Sgk2 |
serum/glucocorticoid regulated kinase 2 |
increases expression |
ISO |
Streptozocin results in increased expression of SGK2 mRNA |
CTD |
PMID:16116964 |
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NCBI chr 3:151,644,102...151,669,480
Ensembl chr 3:151,644,102...151,669,480
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Sgk3 |
serum/glucocorticoid regulated kinase family, member 3 |
increases expression |
ISO |
Streptozocin results in increased expression of SGK3 mRNA |
CTD |
PMID:16116964 |
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NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476
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Sh3glb1 |
SH3 domain -containing GRB2-like endophilin B1 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of SH3GLB1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 2:233,750,838...233,784,817
Ensembl chr 2:233,750,838...233,784,784
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Shc1 |
SHC adaptor protein 1 |
multiple interactions increases expression |
ISO |
SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein] Streptozocin results in increased expression of SHC1 mRNA; Streptozocin results in increased expression of SHC1 protein |
CTD |
PMID:21778425 |
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NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536
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Sim2 |
SIM bHLH transcription factor 2 |
increases expression |
EXP |
Streptozocin results in increased expression of SIM2 protein |
CTD |
PMID:23333261 |
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NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663
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Sirt1 |
sirtuin 1 |
decreases activity multiple interactions decreases expression |
ISO EXP |
Streptozocin results in decreased activity of SIRT1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein; AICA ribonucleotide inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SIRT1 mRNA]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased activity of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [JUN protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [PARP1 protein binds to MMP9 promoter]]; SIRT1 protein inhibits the reaction [Streptozocin promotes the reaction [RELA protein binds to PARP1 protein]]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of CDKN1A]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SHC1 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 mRNA]; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SIRT1 protein] [Streptozocin co-treated with bisphenol A] results in decreased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of SIRT1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of SIRT1 protein; Organoselenium Compounds inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein] Streptozocin results in decreased expression of SIRT1 mRNA; Streptozocin results in decreased expression of SIRT1 protein |
CTD |
PMID:21778425 PMID:22058332 PMID:22733486 PMID:22744176 PMID:23792339 PMID:23859249 PMID:24740756 PMID:24889822 PMID:25301743 PMID:28478229 PMID:31062909 PMID:33812996 PMID:35187753 PMID:35442559 PMID:37337224 More...
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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Slc10a2 |
solute carrier family 10 member 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SLC10A2 mRNA |
CTD |
PMID:29382564 |
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NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
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Slc13a5 |
solute carrier family 13 member 5 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SLC13A5 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr10:56,866,249...56,891,189
Ensembl chr10:56,866,249...56,890,945
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Slc15a3 |
solute carrier family 15 member 3 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of SLC15A3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157
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Slc1a3 |
solute carrier family 1 member 3 |
multiple interactions decreases expression |
EXP |
Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 mRNA]; resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC1A3 protein] Streptozocin results in decreased expression of SLC1A3 mRNA; Streptozocin results in decreased expression of SLC1A3 protein |
CTD |
PMID:23267840 PMID:26677078 |
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NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
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Slc20a2 |
solute carrier family 20 member 2 |
multiple interactions increases expression |
ISO |
INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 mRNA]; INS1 protein inhibits the reaction [Streptozocin results in increased expression of SLC20A2 protein] Streptozocin results in increased expression of SLC20A2 mRNA; Streptozocin results in increased expression of SLC20A2 protein |
CTD |
PMID:29216956 |
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NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711
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Slc22a1 |
solute carrier family 22 member 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of SLC22A1 protein |
CTD |
PMID:19605544 |
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NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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Slc22a2 |
solute carrier family 22 member 2 |
decreases expression |
EXP |
Streptozocin results in decreased expression of SLC22A2 protein |
CTD |
PMID:19605544 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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Slc22a6 |
solute carrier family 22 member 6 |
multiple interactions decreases expression |
EXP |
Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC22A6 protein] |
CTD |
PMID:19634143 |
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NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
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Slc25a1 |
solute carrier family 25 member 1 |
multiple interactions decreases expression |
EXP |
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A1 protein]] |
CTD |
PMID:16595661 |
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NCBI chr11:83,055,764...83,058,781
Ensembl chr11:83,055,748...83,058,781
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Slc25a10 |
solute carrier family 25 member 10 |
increases expression multiple interactions decreases expression |
EXP |
Streptozocin results in increased expression of SLC25A10 protein cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A10 protein]]; Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A10 protein] |
CTD |
PMID:16595661 PMID:19634143 |
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NCBI chr10:105,765,598...105,775,159
Ensembl chr10:105,765,372...105,773,556
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Slc25a19 |
solute carrier family 25 member 19 |
multiple interactions decreases expression |
ISO EXP |
HMOX1 protein inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein] cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A19 protein]] |
CTD |
PMID:16595661 |
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NCBI chr10:100,853,554...100,867,517
Ensembl chr10:100,847,168...100,867,447
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Slc25a20 |
solute carrier family 25 member 20 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of SLC25A20 protein cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC25A20 protein]] |
CTD |
PMID:16595661 |
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NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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Slc25a26 |
solute carrier family 25 member 26 |
affects expression |
ISO |
Streptozocin affects the expression of SLC25A26 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 4:127,036,704...127,131,026
Ensembl chr 4:127,036,742...127,131,020
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Slc25a3 |
solute carrier family 25 member 3 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of SLC25A3 protein Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A3 protein] |
CTD |
PMID:19634143 |
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NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
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Slc25a4 |
solute carrier family 25 member 4 |
multiple interactions |
ISO |
SLC25A4 protein inhibits the reaction [Streptozocin results in increased expression of NPPA mRNA] |
CTD |
PMID:18945756 |
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NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
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Slc25a47 |
solute carrier family 25, member 47 |
affects expression |
ISO |
Streptozocin affects the expression of SLC25A47 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005
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Slc25a5 |
solute carrier family 25 member 5 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of SLC25A5 protein Trientine inhibits the reaction [Streptozocin results in increased expression of SLC25A5 protein] |
CTD |
PMID:19634143 |
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NCBI chr X:116,031,896...116,034,963
Ensembl chr X:116,031,803...116,034,967
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Slc27a1 |
solute carrier family 27 member 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of SLC27A1 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SLC27A1 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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G |
Slc27a5 |
solute carrier family 27 member 5 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC27A5 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172
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Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions increases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein; bicalutamide promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A1 protein]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in increased expression of SLC2A1 mRNA] |
CTD |
PMID:16409969 PMID:35151640 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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Slc2a2 |
solute carrier family 2 member 2 |
increases response to substance decreases expression multiple interactions increases expression |
EXP ISO |
SLC2A2 protein results in increased susceptibility to Streptozocin Streptozocin results in decreased expression of SLC2A2 mRNA 5-thio-D-glucose inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 mRNA]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein; Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; L 783281 inhibits the reaction [Dibutyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A2 protein]] [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA; [Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein; allyl isothiocyanate inhibits the reaction [Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]]; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A2 protein]; repaglinide analog affects the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; repaglinide inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A2 mRNA]; Streptozocin promotes the reaction [Dietary Fats results in decreased expression of SLC2A2 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of SLC2A2 protein] |
CTD |
PMID:11151762 PMID:12137914 PMID:24923654 PMID:25541178 PMID:27417257 PMID:29526571 PMID:30318971 PMID:30927557 PMID:31009641 PMID:33359794 PMID:33724628 PMID:35702883 More...
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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Slc2a4 |
solute carrier family 2 member 4 |
affects expression affects localization decreases expression multiple interactions |
EXP ISO |
Streptozocin affects the expression of SLC2A4 protein Streptozocin affects the localization of SLC2A4 protein Streptozocin results in decreased expression of SLC2A4 mRNA; Streptozocin results in decreased expression of SLC2A4 protein [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein; asiatic acid inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Berberine inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; bis(maltolato)oxovanadium(IV) inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; chebulagic acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; chromium mesoporphyrin inhibits the reaction [Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; cinnamaldehyde inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; cinnamaldehyde inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; eupafolin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Ficusin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; GHRL protein promotes the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Glyburide inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Hemin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; INS protein inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; mangiferin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; myrtenal inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]]; naloxonazine inhibits the reaction [Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; Naloxone inhibits the reaction [Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; naringenin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; nerolidol inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]; piperlongumine inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 mRNA]; Plant Extracts inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Plant Extracts inhibits the reaction [Streptozocin affects the localization of SLC2A4 protein]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; plumbagin inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Polysaccharides inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SLC2A4 protein]; Resveratrol inhibits the reaction [Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]]; Resveratrol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [CAV3 protein binds to SLC2A4 protein]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Tramadol inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SLC2A4 protein] [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein; [Streptozocin co-treated with bisphenol A] results in decreased expression of SLC2A4 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 protein]; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of SLC2A4 protein]; Streptozocin inhibits the reaction [Ethinyl Estradiol results in increased expression of SLC2A4 mRNA]; Streptozocin inhibits the reaction [octylphenol results in increased expression of SLC2A4 mRNA] |
CTD |
PMID:11723065 PMID:12083368 PMID:12658023 PMID:17068109 PMID:17199717 PMID:18266981 PMID:19080170 PMID:19190261 PMID:20219977 PMID:20363216 PMID:21439094 PMID:22960630 PMID:24140466 PMID:26286522 PMID:26616445 PMID:27350165 PMID:27417257 PMID:29223569 PMID:29614383 PMID:29935216 PMID:31743741 PMID:33484791 PMID:33724628 PMID:34470562 PMID:36169646 PMID:37566541 More...
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NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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G |
Slc31a1 |
solute carrier family 31 member 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of SLC31A1 mRNA; Streptozocin results in decreased expression of SLC31A1 protein |
CTD |
PMID:24927960 |
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NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228
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G |
Slc31a2 |
solute carrier family 31 member 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of SLC31A2 mRNA; Streptozocin results in increased expression of SLC31A2 protein Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 mRNA]; Trientine promotes the reaction [Streptozocin results in increased expression of SLC31A2 protein] |
CTD |
PMID:24927960 |
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NCBI chr 5:75,738,008...75,748,542
Ensembl chr 5:75,738,024...75,748,542
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G |
Slc35b2 |
solute carrier family 35 member B2 |
multiple interactions decreases expression |
EXP |
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SLC35B2 protein]] |
CTD |
PMID:16595661 |
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NCBI chr 9:15,438,594...15,442,227
Ensembl chr 9:15,438,594...15,442,234
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G |
Slc3a1 |
solute carrier family 3 member 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of SLC3A1 protein Trientine inhibits the reaction [Streptozocin results in decreased expression of SLC3A1 protein] |
CTD |
PMID:19634143 |
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NCBI chr 6:9,608,169...9,641,881
Ensembl chr 6:9,608,178...9,641,907
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G |
Slc51a |
solute carrier family 51 member A |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51A mRNA |
CTD |
PMID:29382564 |
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NCBI chr11:68,299,086...68,313,485
Ensembl chr11:68,299,086...68,313,485
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G |
Slc51b |
SLC51 subunit beta |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SLC51B mRNA |
CTD |
PMID:29382564 |
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NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145
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G |
Slc6a4 |
solute carrier family 6 member 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein; [Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased activity of SLC6A4 protein]; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of SLC6A4 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384
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G |
Slc6a6 |
solute carrier family 6 member 6 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of SLC6A6 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
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G |
Slc7a7 |
solute carrier family 7 member 7 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of SLC7A7 mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:27,822,088...27,873,121
Ensembl chr15:27,822,091...27,865,648
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G |
Smad1 |
SMAD family member 1 |
increases expression |
EXP |
Streptozocin results in increased expression of SMAD1 |
CTD |
PMID:25617480 |
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NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651
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G |
Smad2 |
SMAD family member 2 |
increases phosphorylation multiple interactions |
EXP ISO |
Streptozocin results in increased phosphorylation of SMAD2 protein [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased phosphorylation of SMAD2 protein; Resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD2 protein] [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD2 protein |
CTD |
PMID:21300041 PMID:31062909 PMID:38282657 |
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NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
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G |
Smad3 |
SMAD family member 3 |
multiple interactions increases phosphorylation |
EXP ISO |
resveratrol inhibits the reaction [Streptozocin results in increased phosphorylation of SMAD3 protein] [fatostatin co-treated with Streptozocin] results in increased phosphorylation of SMAD3 protein; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein]; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased phosphorylation of SMAD3 protein |
CTD |
PMID:21300041 PMID:29420703 PMID:38282657 |
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NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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G |
Smad4 |
SMAD family member 4 |
multiple interactions increases expression decreases expression |
EXP ISO |
Trientine inhibits the reaction [Streptozocin results in increased expression of SMAD4 mRNA] Streptozocin results in increased expression of SMAD4 mRNA; Streptozocin results in increased expression of SMAD4 protein SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA] |
CTD |
PMID:16973718 PMID:18246672 PMID:27629361 |
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NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
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G |
Smad6 |
SMAD family member 6 |
increases expression |
EXP |
Streptozocin results in increased expression of SMAD6 protein |
CTD |
PMID:17437042 |
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NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763
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G |
Smad7 |
SMAD family member 7 |
affects expression decreases expression |
EXP |
Streptozocin affects the expression of SMAD7 mRNA; Streptozocin affects the expression of SMAD7 protein Streptozocin results in decreased expression of SMAD7 mRNA |
CTD |
PMID:17437042 PMID:32959695 |
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NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
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G |
Smpd1 |
sphingomyelin phosphodiesterase 1 |
decreases response to substance |
ISO |
SMPD1 gene mutant form results in decreased susceptibility to Streptozocin |
CTD |
PMID:32481596 |
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NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
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G |
Snap23 |
synaptosome associated protein 23 |
multiple interactions |
EXP |
[Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of SNAP23 mRNA] |
CTD |
PMID:25999625 |
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NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
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G |
Sncb |
synuclein, beta |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SNCB mRNA] |
CTD |
PMID:33484791 |
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NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012
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G |
Sncg |
synuclein, gamma |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of SNCG mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SNCG mRNA] |
CTD |
PMID:16684804 |
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NCBI chr16:9,700,513...9,705,751
Ensembl chr16:9,700,514...9,705,368
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G |
Snord15a |
small nucleolar RNA, C/D box 15A |
increases expression |
ISO |
Streptozocin results in increased expression of SNORD15A mRNA |
CTD |
PMID:27629361 |
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NCBI chr 1:153,782,788...153,782,935
Ensembl chr 1:153,782,788...153,782,935
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G |
Snord49a |
small nucleolar RNA, C/D box 49A |
increases expression |
ISO |
Streptozocin results in increased expression of SNORD49A mRNA |
CTD |
PMID:27629361 |
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NCBI chr10:47,297,488...47,297,559
Ensembl chr10:47,297,488...47,297,559
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G |
Snx12 |
sorting nexin 12 |
multiple interactions decreases expression |
EXP |
[Antagomirs results in decreased expression of MIR140 mRNA] inhibits the reaction [Streptozocin results in decreased expression of SNX12 protein]; Isoflurane promotes the reaction [Streptozocin results in decreased expression of SNX12 protein] |
CTD |
PMID:32062618 |
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NCBI chr X:66,226,995...66,356,945
Ensembl chr X:66,227,053...66,356,950
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G |
Socs3 |
suppressor of cytokine signaling 3 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of SOCS3 protein rosiglitazone inhibits the reaction [Streptozocin results in decreased expression of SOCS3 protein] |
CTD |
PMID:21599458 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
increases expression multiple interactions decreases activity affects expression decreases expression |
ISO EXP |
Streptozocin results in increased expression of SOD1 mRNA [Glyburide co-treated with Dimethyl Fumarate] inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; [Resveratrol co-treated with Streptozocin] results in decreased expression of and results in decreased activity of SOD1 protein; [Resveratrol co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with bisphenol A] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein; allyl methyl sulfide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Dimethyl Fumarate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Dronabinol promotes the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of SOD1 protein]; Glyburide inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in decreased activity of SOD1 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SOD1 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein; Trientine inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD1 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein] Streptozocin affects the expression of SOD1 mRNA 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein; [Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein; Berberine inhibits the reaction [Streptozocin affects the expression of SOD1 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of SOD1 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SOD1 protein] Streptozocin results in decreased expression of SOD1 mRNA; Streptozocin results in decreased expression of SOD1 protein SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of CITED2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ETS1 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MEF2C mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR27A mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of MIR322 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of SMAD4 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR142 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR144 mRNA]; SOD1 protein inhibits the reaction [Streptozocin results in increased expression of MIR448 mRNA] |
CTD |
PMID:15298345 PMID:18583417 PMID:19634143 PMID:20053369 PMID:20654064 PMID:22775417 PMID:23786522 PMID:24707343 PMID:24927960 PMID:25037167 PMID:25905778 PMID:26887929 PMID:27629361 PMID:29606028 PMID:30318971 PMID:31081965 PMID:33359794 PMID:35085591 PMID:35187753 PMID:35442559 PMID:36999408 PMID:37120126 PMID:37482253 More...
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions decreases response to substance affects expression decreases expression decreases activity |
ISO EXP |
Streptozocin results in increased expression of SOD2 mRNA [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein; arjunolic acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Gliclazide inhibits the reaction [[Streptozocin co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 protein]; idebenone inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; INS protein promotes the reaction [Streptozocin results in decreased activity of SOD2 protein]; Plant Extracts inhibits the reaction [Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein]; Streptozocin results in decreased expression of and results in decreased activity of SOD2 protein; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased activity of SOD2 protein]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CAT protein promotes the reaction [SOD2 protein results in decreased susceptibility to Streptozocin]; SOD2 protein promotes the reaction [CAT protein results in decreased susceptibility to Streptozocin] [Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA; [Streptozocin co-treated with INS1 protein co-treated with Glutathione] affects the expression of SOD2 mRNA; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Berberine inhibits the reaction [Streptozocin affects the expression of SOD2 mRNA]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SOD2 mRNA]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Quercetin inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; SIRT1 protein inhibits the reaction [Streptozocin results in decreased expression of SOD2]; SOD2 protein inhibits the reaction [Streptozocin results in increased phosphorylation of MAPT protein] Streptozocin results in decreased expression of SOD2; Streptozocin results in decreased expression of SOD2 protein Streptozocin results in decreased expression of SOD2 mRNA; Streptozocin results in decreased expression of SOD2 protein |
CTD |
PMID:14871415 PMID:15298345 PMID:15855331 PMID:18779489 PMID:19634143 PMID:19951573 PMID:20053369 PMID:20654064 PMID:20976160 PMID:21778425 PMID:21799698 PMID:22744176 PMID:22775417 PMID:22940631 PMID:25362599 PMID:25905778 PMID:26887929 PMID:28499986 PMID:33359794 PMID:34175429 PMID:35442559 PMID:35786680 More...
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sod3 |
superoxide dismutase 3 |
multiple interactions decreases expression |
EXP ISO |
cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]; tin mesoporphyrin inhibits the reaction [cobaltiprotoporphyrin inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein]]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 mRNA]; Trientine inhibits the reaction [Streptozocin results in decreased expression of SOD3 protein] Streptozocin results in decreased expression of SOD3 mRNA; Streptozocin results in decreased expression of SOD3 protein [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Peroxynitrous Acid; [Streptozocin results in decreased activity of SOD3 protein] which results in increased chemical synthesis of Superoxides; Copper inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; INS protein inhibits the reaction [Streptozocin results in decreased activity of SOD3 protein]; SOD3 gene mutant form promotes the reaction [Streptozocin results in increased chemical synthesis of Superoxides]; Streptozocin results in increased expression of and results in decreased activity of SOD3 protein |
CTD |
PMID:15821039 PMID:16973718 PMID:23884884 |
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NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
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G |
Sord |
sorbitol dehydrogenase |
multiple interactions increases expression increases glycation |
EXP |
Streptozocin results in decreased expression of and results in decreased activity of SORD protein Streptozocin results in increased expression of SORD mRNA Streptozocin results in increased glycation of SORD protein |
CTD |
PMID:8761460 |
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NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133
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G |
Sort1 |
sortilin 1 |
decreases expression |
ISO |
Streptozocin results in decreased expression of SORT1 protein |
CTD |
PMID:25805502 |
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NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354
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G |
Sox11 |
SRY-box transcription factor 11 |
decreases expression |
EXP |
Streptozocin results in decreased expression of SOX11 mRNA; Streptozocin results in decreased expression of SOX11 protein |
CTD |
PMID:32935389 |
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NCBI chr 6:44,008,333...44,010,354
Ensembl chr 6:44,008,340...44,010,354
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G |
Spag9 |
sperm associated antigen 9 |
decreases expression |
EXP |
Streptozocin results in decreased expression of SPAG9 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:78,943,439...79,077,797
Ensembl chr10:78,943,479...79,077,797
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G |
Sparc |
secreted protein acidic and cysteine rich |
increases expression |
ISO |
Streptozocin results in increased expression of SPARC mRNA; Streptozocin results in increased expression of SPARC protein |
CTD |
PMID:12660331 |
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NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Sphk1 |
sphingosine kinase 1 |
increases expression |
ISO EXP |
Streptozocin results in increased expression of SPHK1 Streptozocin results in increased expression of SPHK1 mRNA; Streptozocin results in increased expression of SPHK1 protein |
CTD |
PMID:19657322 PMID:21998146 |
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NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240
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G |
Spmip11 |
sperm microtubule inner protein 11 |
decreases expression multiple interactions increases secretion |
EXP |
Streptozocin results in decreased expression of NPHS1 mRNA; Streptozocin results in decreased expression of NPHS1 protein [Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Drugs, Chinese Herbal inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of NPHS1 protein]; stannous mesoporphyrin inhibits the reaction [4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [Streptozocin results in increased secretion of NPHS1 protein]]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein] |
CTD |
PMID:17624267 PMID:20547220 PMID:23611540 PMID:25199697 PMID:30551545 |
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NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
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G |
Spp1 |
secreted phosphoprotein 1 |
multiple interactions increases expression |
EXP |
Pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein]; vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA] Streptozocin results in increased expression of SPP1 mRNA; Streptozocin results in increased expression of SPP1 protein |
CTD |
PMID:16684804 PMID:16979161 PMID:16980342 |
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Sprr2a2 |
small proline-rich protein 2A2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of SPRR2A2 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SPRR2A2 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 2:177,719,576...177,719,845
Ensembl chr 2:177,719,576...177,719,845
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G |
Spsb4 |
splA/ryanodine receptor domain and SOCS box containing 4 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of SPSB4 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:97,536,519...97,609,757
Ensembl chr 8:97,536,520...97,609,787
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions increases expression |
ISO EXP |
bafilomycin A1 inhibits the reaction [Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]]; HU 308 inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of SQSTM1 protein]; Streptozocin promotes the reaction [bafilomycin A1 results in increased expression of SQSTM1 protein] [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SQSTM1 protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of SQSTM1 protein |
CTD |
PMID:24889822 PMID:30459625 PMID:35786680 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Srd5a1 |
steroid 5 alpha-reductase 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of SRD5A1 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions increases expression decreases expression increases expression |
EXP ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein] Streptozocin results in increased expression of SREBF1 mRNA; Streptozocin results in increased expression of SREBF1 protein Streptozocin results in decreased expression of SREBF1 protein [Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA; Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF1 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF1 protein]; ginsenoside Rh4 inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of SREBF1 mRNA]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA]; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of SREBF1 mRNA] streptozocin increases expression of Srebf1 protein in liver |
CTD RGD |
PMID:22031849 PMID:23647015 PMID:25240712 PMID:28822685 PMID:29420703 PMID:29988851 PMID:31100278 PMID:33359794 PMID:33812996 PMID:34896238 PMID:35786680 PMID:32535406 More...
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RGD:401850547 |
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Srebf2 |
sterol regulatory element binding transcription factor 2 |
multiple interactions increases expression |
EXP ISO |
[[Dietary Fats co-treated with Carbamazepine] affects the susceptibility to Streptozocin] which results in decreased expression of SREBF2 mRNA; [[Streptozocin co-treated with Carbamazepine] affects the susceptibility to Dietary Fats] which results in decreased expression of SREBF2 mRNA; [Dietary Fats co-treated with Streptozocin co-treated with Carbamazepine] results in decreased expression of SREBF2 mRNA; [Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein] Streptozocin results in increased expression of SREBF2 mRNA; Streptozocin results in increased expression of SREBF2 protein Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA]; fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein] |
CTD |
PMID:23647015 PMID:25240712 PMID:29420703 PMID:34896238 PMID:35786680 |
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NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
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G |
Srxn1 |
sulfiredoxin 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA; Omaveloxolone analog promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA]; Omaveloxolone promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of SRXN1 mRNA] |
CTD |
PMID:32410268 |
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NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
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G |
St3gal5 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of ST3GAL5 mRNA vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of ST3GAL5 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558
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G |
Stac3 |
SH3 and cysteine rich domain 3 |
decreases expression |
EXP |
Streptozocin results in decreased expression of STAC3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
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G |
Stag3 |
STAG3 cohesin complex component |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of STAG3 mRNA |
CTD |
PMID:33484791 |
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NCBI chr12:17,284,677...17,314,936
Ensembl chr12:17,284,794...17,314,935
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions increases expression increases phosphorylation decreases phosphorylation |
EXP |
7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of STAT3 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Phosphocreatine inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Propofol promotes the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Rosiglitazone inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein]; Simvastatin inhibits the reaction [Streptozocin results in increased phosphorylation of STAT3 protein] Streptozocin results in increased expression of STAT3 mRNA; Streptozocin results in increased expression of STAT3 protein |
CTD |
PMID:19958114 PMID:20821229 PMID:21599458 PMID:21912612 PMID:24810525 PMID:29291386 PMID:34455488 PMID:36650709 More...
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Stub1 |
STIP1 homology and U-box containing protein 1 |
multiple interactions |
EXP |
STUB1 inhibits the reaction [Streptozocin results in decreased expression of AKT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of GSK3B protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of NFE2L2 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of and results in decreased phosphorylation of PRKAA1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of HMOX1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of PPARGC1A protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SIRT1 protein]; STUB1 inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of IL1B protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of RELA protein]; STUB1 inhibits the reaction [Streptozocin results in increased phosphorylation of TNFA protein] |
CTD |
PMID:35442559 |
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NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046
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G |
Stx4 |
syntaxin 4 |
multiple interactions |
EXP |
[Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of STX4 mRNA] |
CTD |
PMID:25999625 |
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NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979
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G |
Sucla2 |
succinate-CoA ligase ADP-forming subunit beta |
affects expression |
ISO |
Streptozocin affects the expression of SUCLA2 mRNA |
CTD |
PMID:18583417 |
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NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138
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G |
Sult1c2a |
sulfotransferase family 1C member 2A |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of SULT1C2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
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G |
Sult2a1 |
sulfotransferase family 2A member 1 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in increased expression of SULT2A1 mRNA |
CTD |
PMID:29382564 |
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NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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G |
Syp |
synaptophysin |
increases expression multiple interactions decreases expression |
ISO EXP |
Streptozocin results in increased expression of SYP mRNA Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Physostigmine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; telmisartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Valsartan inhibits the reaction [Streptozocin results in decreased expression of SYP protein] fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP mRNA]; fasudil inhibits the reaction [Streptozocin results in decreased expression of SYP protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of SYP protein] Streptozocin results in decreased expression of SYP mRNA; Streptozocin results in decreased expression of SYP protein |
CTD |
PMID:18487452 PMID:22062134 PMID:28499986 PMID:38049026 |
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NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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G |
Syvn1 |
synoviolin 1 |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of SYVN1 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in decreased expression of SYVN1 protein] |
CTD |
PMID:30980806 |
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NCBI chr 1:203,339,235...203,346,137
Ensembl chr 1:203,339,619...203,346,152
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G |
Tac1 |
tachykinin, precursor 1 |
multiple interactions decreases expression increases expression decreases secretion |
EXP |
Botulinum Toxins, Type A inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; Butylated Hydroxytoluene inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; capsazepine inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; imirestat inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; RN 1734 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein]; sorbinil inhibits the reaction [Streptozocin results in increased expression of TAC1 mRNA]; Streptozocin promotes the reaction [KNG1 protein modified form results in increased secretion of TAC1 protein modified form]; U 0126 inhibits the reaction [Streptozocin results in decreased expression of TAC1 protein] Streptozocin results in decreased secretion of TAC1 protein modified form |
CTD |
PMID:1374869 PMID:9748608 PMID:20832942 PMID:30583000 |
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NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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G |
Tbc1d4 |
TBC1 domain family, member 4 |
multiple interactions |
ISO |
[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased expression of and results in decreased phosphorylation of TBC1D4 protein; Metformin inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein]; perilla seed oil inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in decreased phosphorylation of TBC1D4 protein] |
CTD |
PMID:31743741 |
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NCBI chr15:78,256,030...78,434,168
Ensembl chr15:78,257,121...78,434,265
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G |
Tedc1 |
tubulin epsilon and delta complex 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TEDC1 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 6:132,234,764...132,245,164
Ensembl chr 6:132,236,925...132,244,928
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G |
Tek |
TEK receptor tyrosine kinase |
multiple interactions increases expression decreases expression |
EXP |
baicalin inhibits the reaction [Streptozocin results in decreased expression of TEK mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TEK mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of TEK mRNA] Streptozocin results in increased expression of TEK mRNA; Streptozocin results in increased expression of TEK protein |
CTD |
PMID:15643138 PMID:19958114 PMID:20821229 PMID:34414639 |
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NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA; tianhuang inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TFAM mRNA] |
CTD |
PMID:37337224 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tfap2a |
transcription factor AP-2 alpha |
multiple interactions |
EXP ISO |
MFN2 protein mutant form inhibits the reaction [Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter]]; Streptozocin promotes the reaction [TFAP2A protein binds to COL4A1 promoter] [Streptozocin co-treated with Raloxifene Hydrochloride] results in increased expression of TFAP2A protein |
CTD |
PMID:23471663 PMID:27997345 |
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NCBI chr17:24,028,716...24,047,507
Ensembl chr17:24,024,432...24,047,507
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G |
Tfrc |
transferrin receptor |
multiple interactions increases expression |
EXP |
iron pentacarbonyl inhibits the reaction [Streptozocin results in increased expression of TFRC mRNA] |
CTD |
PMID:22170771 |
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NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfb1 |
transforming growth factor, beta 1 |
increases expression multiple interactions increases secretion decreases methylation decreases expression decreases secretion |
ISO EXP |
Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [fatostatin co-treated with Streptozocin] results in increased expression of TGFB1 mRNA; [Huang Qi co-treated with Coptidis rhizoma extract co-treated with Aconitic Acid co-treated with Centella asiatica extract] inhibits the reaction [[Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with NG-Nitroarginine Methyl Ester] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein; bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of TGFB1 protein]; CEBPB protein affects the reaction [Streptozocin results in increased expression of TGFB1 protein]; Chlorpyrifos inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 mRNA]; KLF15 gene mutant form inhibits the reaction [CXCL12 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]]; KLF15 gene mutant form promotes the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TGFB1 protein]; Rosuvastatin Calcium inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; sarpogrelate inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; sulforaphane inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] Streptozocin results in increased secretion of TGFB1 protein 1-hexacosanol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]]; 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]]; 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein; [Streptozocin co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in increased expression of TGFB1 protein; [Streptozocin co-treated with Resveratrol] results in increased expression of TGFB1 protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; baicalin inhibits the reaction [Streptozocin results in decreased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; crocin promotes the reaction [Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; danggui buxue decoction inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; dapagliflozin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; esculetin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fasudil inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; fenugreek seed meal inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Flavonoids inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Gallic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; mangiferin inhibits the reaction [Streptozocin results in increased secretion of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TGFB1 protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]; Quercetin promotes the reaction [crocin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TGFB1 protein]]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Trientine inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Vitamin E inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; XLF-III-43 inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]; zingerone inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] Streptozocin results in increased expression of TGFB1; Streptozocin results in increased expression of TGFB1 mRNA; Streptozocin results in increased expression of TGFB1 protein [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 mRNA; [ALPK1 protein results in increased susceptibility to Streptozocin] which results in increased expression of TGFB1 protein Streptozocin results in decreased methylation of TGFB1 promoter |
CTD |
PMID:11798641 PMID:12660331 PMID:14586741 PMID:15309289 PMID:16409969 PMID:16523407 PMID:16859672 PMID:16973718 PMID:16980342 PMID:17437042 PMID:18246672 PMID:19895808 PMID:19960420 PMID:20844835 PMID:21300041 PMID:21381899 PMID:21450970 PMID:23376009 PMID:23611540 PMID:23733546 PMID:24707343 PMID:24877639 PMID:24967692 PMID:25057273 PMID:25240712 PMID:26341651 PMID:27097221 PMID:27542954 PMID:28700904 PMID:28904557 PMID:29266779 PMID:29291386 PMID:29331653 PMID:29409856 PMID:29420703 PMID:29953732 PMID:29988851 PMID:30551545 PMID:31009641 PMID:31062909 PMID:31323227 PMID:31696645 PMID:31726037 PMID:32469605 PMID:33021114 PMID:33387473 PMID:33524429 PMID:33631230 PMID:34310909 PMID:34414639 PMID:34922902 PMID:35051763 PMID:36650709 PMID:37120126 PMID:37224990 PMID:37352119 PMID:38282657 More...
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfbr1 |
transforming growth factor, beta receptor 1 |
multiple interactions increases expression affects expression |
EXP ISO |
benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TGFBR1 protein] Streptozocin results in increased expression of TGFBR1 mRNA; Streptozocin results in increased expression of TGFBR1 protein Streptozocin affects the expression of TGFBR1 mRNA fatostatin inhibits the reaction [Streptozocin results in increased expression of TGFBR1 mRNA] |
CTD |
PMID:11798618 PMID:26073000 PMID:29420703 |
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NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
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G |
Tgfbr2 |
transforming growth factor, beta receptor 2 |
decreases expression |
ISO |
Streptozocin results in decreased expression of TGFBR2 protein |
CTD |
PMID:15496156 |
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NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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G |
Tgfbr3 |
transforming growth factor beta receptor 3 |
multiple interactions |
EXP |
[Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of TGFBR3 protein |
CTD |
PMID:31062909 |
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NCBI chr14:2,489,397...2,665,383
Ensembl chr14:2,489,397...2,663,341
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G |
Th |
tyrosine hydroxylase |
multiple interactions decreases expression |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TH protein]; Vitamin B 12 inhibits the reaction [Streptozocin results in decreased expression of TH protein] |
CTD |
PMID:35085591 PMID:38049026 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Thbd |
thrombomodulin |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of THBD mRNA |
CTD |
PMID:25905778 |
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NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
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G |
Thbs1 |
thrombospondin 1 |
multiple interactions increases expression |
EXP |
pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein] Streptozocin results in increased expression of THBS1 mRNA; Streptozocin results in increased expression of THBS1 protein |
CTD |
PMID:17063547 PMID:17117553 |
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NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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G |
Thbs2 |
thrombospondin 2 |
increases expression |
ISO |
Streptozocin results in increased expression of THBS2 protein |
CTD |
PMID:23723366 |
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NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789
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G |
Thbs4 |
thrombospondin 4 |
multiple interactions increases expression |
EXP |
vanadyl sulfate inhibits the reaction [Streptozocin results in increased expression of THBS4 mRNA] |
CTD |
PMID:16684804 |
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NCBI chr 2:23,983,158...24,025,289
Ensembl chr 2:23,983,158...24,026,313
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions decreases expression |
EXP ISO |
Fructose inhibits the reaction [Streptozocin results in decreased expression of THRSP mRNA] [Streptozocin co-treated with Dietary Fats] results in decreased expression of THRSP mRNA |
CTD |
PMID:2177838 PMID:29127188 |
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NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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G |
Timm8b |
translocase of inner mitochondrial membrane 8 homolog B |
affects expression |
ISO |
Streptozocin affects the expression of TIMM8B mRNA |
CTD |
PMID:18583417 |
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NCBI chr 8:50,954,350...50,955,730
Ensembl chr 8:50,954,342...50,955,729
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
increases expression multiple interactions increases activity decreases expression |
EXP |
Streptozocin results in increased expression of TIMP1 mRNA [Resveratrol co-treated with Streptozocin] results in increased expression of TIMP1 mRNA; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP1 protein]; rhapontin inhibits the reaction [Streptozocin results in decreased expression of TIMP1 mRNA] |
CTD |
PMID:18246672 PMID:25246140 PMID:25905778 PMID:32662907 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
increases expression multiple interactions increases activity increases secretion |
EXP ISO |
Streptozocin results in increased expression of TIMP2 mRNA; Streptozocin results in increased expression of TIMP2 protein benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; benazepril inhibits the reaction [Streptozocin results in increased expression of TIMP2 protein]; Olive Oil promotes the reaction [Streptozocin results in increased activity of TIMP2 protein] Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased expression of TIMP2 mRNA]; Raloxifene Hydrochloride inhibits the reaction [Streptozocin results in increased secretion of TIMP2 protein] |
CTD |
PMID:16732983 PMID:20821936 PMID:23471663 PMID:25246140 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Tinag |
tubulointerstitial nephritis antigen |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of TINAG protein Trientine inhibits the reaction [Streptozocin results in increased expression of TINAG protein] |
CTD |
PMID:19634143 |
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NCBI chr 8:77,800,031...77,885,077
Ensembl chr 8:77,800,032...77,885,077
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G |
Tjp1 |
tight junction protein 1 |
multiple interactions decreases expression |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP1 protein]; rhodioloside inhibits the reaction [Streptozocin results in decreased expression of TJP1 protein] |
CTD |
PMID:27783111 PMID:31682803 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tjp2 |
tight junction protein 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein; NLRP3 protein promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TJP2 protein] |
CTD |
PMID:27783111 |
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NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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G |
Tkt |
transketolase |
multiple interactions |
EXP |
[benphothiamine co-treated with Streptozocin] results in increased activity of TKT protein |
CTD |
PMID:12592403 |
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NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
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G |
Tlr3 |
toll-like receptor 3 |
multiple interactions increases expression |
ISO |
TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA] |
CTD |
PMID:20446767 |
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NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
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G |
Tlr4 |
toll-like receptor 4 |
multiple interactions increases expression |
ISO EXP |
TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA] [Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 protein]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TLR4 mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TLR4 mRNA] crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TLR4 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] Streptozocin results in increased expression of TLR4 mRNA; Streptozocin results in increased expression of TLR4 protein |
CTD |
PMID:20446767 PMID:27769711 PMID:29409856 PMID:34477272 PMID:34610774 PMID:36504472 PMID:37224990 PMID:37482253 More...
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NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
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G |
Tmed3 |
transmembrane p24 trafficking protein 3 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of TMED3 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:90,241,516...90,249,429
Ensembl chr 8:90,241,516...90,249,346
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G |
Tmsb10 |
thymosin, beta 10 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of TMSB10 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 4:105,009,959...105,011,095
Ensembl chr 4:105,009,212...105,011,028
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases expression increases secretion decreases expression |
ISO EXP |
PRDX4 protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR3 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TLR4 mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA] 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; 2,5-dihydroxybenzoic acid inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; 3-((6-(2-methoxyphenyl)pyrimidin-4-yl)amino)phenyl)methane sulfonamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Streptozocin co-treated with bisphenol A] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in decreased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with octylphenol] results in increased expression of TNF mRNA; [Streptozocin co-treated with Particulate Matter] results in increased expression of TNF protein; [Streptozocin co-treated with Vehicle Emissions] results in increased expression of TNF protein; Acrylamide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Alendronate inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; AM6545 promotes the reaction [Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Ascorbic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; asiatic acid promotes the reaction [Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased secretion of TNF protein]; Carnosine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Carnosine promotes the reaction [asiatic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Donepezil inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Dronabinol inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; esculetin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; etiron promotes the reaction [Streptozocin results in increased expression of TNF protein]; Genistein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of TNF protein]; Glucagon analog inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; MIR29A mRNA inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; montelukast inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Perindopril inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; Perindopril promotes the reaction [AM6545 inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF mRNA]; scutellarin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Sodium Selenite inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein] Streptozocin results in increased expression of TNF mRNA; Streptozocin results in increased expression of TNF protein Streptozocin results in increased secretion of TNF protein Streptozocin results in decreased expression of TNF protein 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; 4-methyl-2-((2-methylbenzyl) amino)-1,3-thiazole-5-carboxylic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; 7,3'-dihydroxy-4'-methoxyisoflavone inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; 7-hydroxycoumarin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin co-treated with Quercetin] affects the expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA; [Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein; [Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein; [pimagedine co-treated with Fatty Acids, Omega-3] inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of TNF protein]; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein; [Streptozocin co-treated with Fructose] results in increased expression of TNF protein; [Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein; [Streptozocin co-treated with Sodium Glutamate] results in increased expression of TNF protein; [Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; [Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Acetates inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; arjunolic acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; bisacurone inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; caffeic acid phenethyl ester inhibits the reaction [Streptozocin results in increased expression of TNF protein]; caryophyllene inhibits the reaction [Streptozocin results in increased expression of TNF protein]; chromium nicotinic acid complex inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in decreased expression of TNF protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; dapagliflozin promotes the reaction [Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Diosgenin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; diphenyldiselenide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Ellagic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Enalapril inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF mRNA]; Fungal Polysaccharides inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Gallic Acid inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Gliclazide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Glyburide inhibits the reaction [[Dietary Sugars co-treated with Dietary Fats co-treated with Streptozocin] results in increased expression of TNF protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TNF protein]; hesperetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Ibuprofen inhibits the reaction [Streptozocin results in increased expression of TNF protein]; IGF2R protein modified form promotes the reaction [Streptozocin results in increased expression of TNF protein]; Insulin promotes the reaction [Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of TNF protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Memantine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of and results in increased secretion of TNF protein]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Metformin promotes the reaction [[Dietary Fats co-treated with Streptozocin] inhibits the reaction [Ovalbumin results in increased expression of TNF protein]]; morin analog inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; myrtenol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; nifuroxazide inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Ozone inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Pentoxifylline inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; picolinic acid inhibits the reaction [Streptozocin results in increased secretion of TNF protein]; pinitol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of TNF protein]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; piperlongumine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Plant Extracts inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Pyridoxamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Quercetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Niacinamide co-treated with Streptozocin] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in increased expression of TNF protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TNF protein]; rhapontin inhibits the reaction [Streptozocin results in increased expression of TNF mRNA]; Rivastigmine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; SMe1EC2 promotes the reaction [Streptozocin results in increased expression of TNF protein]; sodium arsenate promotes the reaction [Streptozocin results in increased expression of TNF protein]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF mRNA]; Streptozocin promotes the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of TNF protein]; Streptozocin results in increased expression of and results in increased secretion of TNF protein; sulbutiamine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Thioctic Acid inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Wortmannin inhibits the reaction [Phycocyanin inhibits the reaction [Streptozocin results in increased expression of TNF protein]]; Zinc Compounds inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNF protein]; Zinc inhibits the reaction [Streptozocin results in increased expression of TNF mRNA] |
CTD |
PMID:11357882 PMID:12123627 PMID:15309289 PMID:15862027 PMID:15892581 PMID:15975818 PMID:16129698 PMID:16336586 PMID:17167242 PMID:17589825 PMID:17854708 PMID:18789669 PMID:18999900 PMID:19133311 PMID:19279317 PMID:19682444 PMID:20053369 PMID:20223228 PMID:20307516 PMID:20446767 PMID:20643114 PMID:20665664 PMID:21439094 PMID:21439372 PMID:21457706 PMID:21912612 PMID:23147376 PMID:24333387 PMID:24508943 PMID:24513509 PMID:24707343 PMID:24760747 PMID:24781736 PMID:24854284 PMID:24877639 PMID:25541178 PMID:26341651 PMID:26614261 PMID:26748309 PMID:27702591 PMID:27769711 PMID:28259689 PMID:28700904 PMID:29127188 PMID:29233026 PMID:29291386 PMID:29988851 PMID:30144451 PMID:30184259 PMID:30481507 PMID:30551545 PMID:30611788 PMID:30642005 PMID:30802477 PMID:30817903 PMID:31009641 PMID:31081965 PMID:31100278 PMID:31323227 PMID:31726037 PMID:32554039 PMID:32662907 PMID:32805344 PMID:33524429 PMID:33631230 PMID:33639173 PMID:33724628 PMID:34039237 PMID:34391751 PMID:34477272 PMID:34610774 PMID:34656705 PMID:34896238 PMID:34922902 PMID:35085591 PMID:35305976 PMID:36462176 PMID:36504472 PMID:36510688 PMID:36547818 PMID:36650709 PMID:37044004 PMID:37120126 PMID:37224990 PMID:37482253 PMID:38084638 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip1 |
TNF alpha induced protein 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TNFAIP1 mRNA |
CTD |
PMID:20665664 |
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NCBI chr10:63,417,774...63,432,466
Ensembl chr10:63,417,775...63,432,466
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G |
Tnfrsf11b |
TNF receptor superfamily member 11B |
decreases expression |
EXP |
Streptozocin results in decreased expression of TNFRSF11B mRNA |
CTD |
PMID:25617479 |
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NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions increases expression |
ISO |
TNF protein inhibits the reaction [Streptozocin results in increased expression of TNFRSF1B mRNA] |
CTD |
PMID:20446767 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tnfrsf8 |
TNF receptor superfamily member 8 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of TNFRSF8 mRNA; [Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TNFRSF8 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421
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G |
Tnfrsf9 |
TNF receptor superfamily member 9 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of TNFRSF9 mRNA |
CTD |
PMID:33484791 |
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NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
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G |
Tomm40 |
translocase of outer mitochondrial membrane 40 |
affects expression |
ISO |
Streptozocin affects the expression of TOMM40 mRNA |
CTD |
PMID:18583417 |
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NCBI chr 1:79,358,781...79,370,882
Ensembl chr 1:79,358,786...79,370,915
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G |
Tp53 |
tumor protein p53 |
multiple interactions increases expression |
ISO EXP |
2-amino-6-boronohexanoic acid inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TRP53 protein; IGF1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 protein]; NTN1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53 mRNA]; SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of TRP53] Streptozocin results in increased expression of TRP53; Streptozocin results in increased expression of TRP53 mRNA; Streptozocin results in increased expression of TRP53 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; [Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein; dapagliflozin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of TP53 protein]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Glyburide inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; isoquercitrin inhibits the reaction [Streptozocin results in increased expression of TP53 mRNA]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of TP53 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TP53 protein] Streptozocin results in increased expression of TP53 mRNA; Streptozocin results in increased expression of TP53 protein |
CTD |
PMID:11375343 PMID:15976052 PMID:22744176 PMID:23792339 PMID:29059224 PMID:29673160 PMID:30817903 PMID:30980806 PMID:33387473 PMID:34391751 PMID:38483099 More...
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tph2 |
tryptophan hydroxylase 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA; Diethylhexyl Phthalate promotes the reaction [[Streptozocin co-treated with Dietary Fats co-treated with Dietary Sugars] results in decreased expression of TPH2 mRNA] |
CTD |
PMID:32303808 |
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NCBI chr 7:50,685,694...50,789,424
Ensembl chr 7:50,685,694...50,789,424
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G |
Traf6 |
TNF receptor associated factor 6 |
multiple interactions increases expression |
EXP ISO |
Glyburide inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein]; Tropisetron inhibits the reaction [Streptozocin results in increased expression of TRAF6 protein] [Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA; bergenin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAF6 mRNA] |
CTD |
PMID:36504472 PMID:37482253 |
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NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
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G |
Trat1 |
T cell receptor associated transmembrane adaptor 1 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TRAT1 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr11:52,035,750...52,077,805
Ensembl chr11:52,035,750...52,077,805
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G |
Treh |
trehalase |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TREH mRNA |
CTD |
PMID:29127188 |
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NCBI chr 8:44,990,182...45,003,881
Ensembl chr 8:44,990,182...45,003,540
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G |
Trh |
thyrotropin releasing hormone |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of TRH mRNA TRH protein inhibits the reaction [Streptozocin inhibits the reaction [Blood Glucose results in increased secretion of INS1 protein]] |
CTD |
PMID:16118471 |
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NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
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G |
Trib3 |
tribbles pseudokinase 3 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRIB3 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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G |
Trpm4 |
transient receptor potential cation channel, subfamily M, member 4 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of TRPM4 mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532
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G |
Trpv4 |
transient receptor potential cation channel, subfamily V, member 4 |
increases response to substance |
EXP |
TRPV4 protein results in increased susceptibility to Streptozocin |
CTD |
PMID:18234883 |
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NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517
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G |
Trpv5 |
transient receptor potential cation channel, subfamily V, member 5 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of TRPV5 mRNA formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV5 mRNA] |
CTD |
PMID:35315182 |
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NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745
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G |
Trpv6 |
transient receptor potential cation channel, subfamily V, member 6 |
multiple interactions decreases expression |
ISO |
[bisphenol A co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; [Ethinyl Estradiol co-treated with Streptozocin] results in increased expression of TRPV6 mRNA; formononetin inhibits the reaction [Streptozocin results in decreased expression of TRPV6 mRNA] |
CTD |
PMID:29935216 PMID:35315182 |
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NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
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G |
Tsc22d1 |
TSC22 domain family, member 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of TSC22D1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
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G |
Tspan8 |
tetraspanin 8 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of TSPAN8 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:51,444,946...51,479,360
Ensembl chr 7:51,445,074...51,479,356
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G |
Tspo |
translocator protein |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of TSPO mRNA |
CTD |
PMID:25905778 |
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NCBI chr 7:114,720,188...114,730,450
Ensembl chr 7:114,720,188...114,730,450
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G |
Ttll8 |
tubulin tyrosine ligase like 8 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of TTLL8 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 7:120,000,638...120,046,556
Ensembl chr 7:120,001,794...120,045,075
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G |
Ttr |
transthyretin |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of TTR protein Trientine inhibits the reaction [Streptozocin results in decreased expression of TTR protein] |
CTD |
PMID:19634143 |
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NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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G |
Txn1 |
thioredoxin 1 |
multiple interactions |
ISO |
TXN protein inhibits the reaction [Streptozocin results in increased secretion of ALB protein] |
CTD |
PMID:17360766 |
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NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
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G |
Txnip |
thioredoxin interacting protein |
increases expression multiple interactions |
ISO EXP |
Streptozocin results in increased expression of TXNIP mRNA Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Allopurinol inhibits the reaction [Streptozocin results in increased expression of TXNIP protein]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP mRNA]; Quercetin inhibits the reaction [Streptozocin results in increased expression of TXNIP protein] Streptozocin results in increased expression of TXNIP mRNA; Streptozocin results in increased expression of TXNIP protein [Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein; aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of TXNIP protein] |
CTD |
PMID:17582205 PMID:23647015 PMID:35961541 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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G |
Txnrd1 |
thioredoxin reductase 1 |
increases expression |
EXP |
Streptozocin results in increased expression of TXNRD1 mRNA |
CTD |
PMID:12398930 |
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NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Tyrobp |
transmembrane immune signaling adaptor Tyrobp |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in increased expression of TYROBP mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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G |
Uba1 |
ubiquitin-like modifier activating enzyme 1 |
multiple interactions increases expression |
EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UBA1 protein] |
CTD |
PMID:30980806 |
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NCBI chr X:1,508,700...1,530,677
Ensembl chr X:1,508,666...1,530,636
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
decreases expression increases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of UCHL1 protein Streptozocin results in increased expression of UCHL1 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL1 protein] |
CTD |
PMID:30583000 PMID:30980806 |
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NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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G |
Uchl5 |
ubiquitin C-terminal hydrolase L5 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of UCHL5 protein 4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of UCHL5 protein] |
CTD |
PMID:30980806 |
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NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
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G |
Ucp2 |
uncoupling protein 2 |
multiple interactions |
ISO |
[Dietary Fats co-treated with Streptozocin] results in decreased expression of UCP2 mRNA |
CTD |
PMID:33359794 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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G |
Ucp3 |
uncoupling protein 3 |
increases expression |
ISO |
Streptozocin results in increased expression of UCP3 protein |
CTD |
PMID:16306367 |
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NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
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G |
Uqcrb |
ubiquinol-cytochrome c reductase binding protein |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA; Metformin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of UQCRB mRNA] |
CTD |
PMID:37337224 |
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NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150
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G |
Uqcrc1 |
ubiquinol-cytochrome c reductase core protein 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of UQCRC1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of UQCRC1 protein] |
CTD |
PMID:19634143 PMID:21136691 |
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NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
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G |
Usp15 |
ubiquitin specific peptidase 15 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of USP15 mRNA; Streptozocin results in increased expression of USP15 protein benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 mRNA]; MIR497 inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; NFE2L2 protein inhibits the reaction [Streptozocin results in increased expression of USP15 protein]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 mRNA]; USP15 protein inhibits the reaction [Streptozocin results in decreased expression of NFE2L2 protein] |
CTD |
PMID:35478295 |
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NCBI chr 7:58,756,714...58,848,778
Ensembl chr 7:58,756,872...58,848,721
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G |
Usp16 |
ubiquitin specific peptidase 16 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP16 mRNA] |
CTD |
PMID:28946194 |
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NCBI chr11:26,681,359...26,711,313
Ensembl chr11:26,681,414...26,710,539
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G |
Usp2 |
ubiquitin specific peptidase 2 |
increases expression |
EXP |
Streptozocin results in increased expression of USP2 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
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G |
Usp22 |
ubiquitin specific peptidase 22 |
multiple interactions |
EXP |
[Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of USP22 mRNA] |
CTD |
PMID:28946194 |
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NCBI chr10:45,828,619...45,855,468
Ensembl chr10:45,828,622...45,855,497
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G |
Usp27x |
ubiquitin specific peptidase 27, X-linked |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of USP27X protein baicalin inhibits the reaction [Streptozocin results in increased expression of USP27X protein] |
CTD |
PMID:34414639 |
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NCBI chr X:15,123,620...15,126,855
Ensembl chr X:15,124,596...15,125,912
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G |
Vamp2 |
vesicle-associated membrane protein 2 |
multiple interactions |
EXP |
[Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA; resveratrol inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased expression of VAMP2 mRNA] |
CTD |
PMID:25999625 |
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NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions increases expression |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; Atorvastatin inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Bezafibrate inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; candesartan inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; esculetin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 mRNA]; KLK1 protein inhibits the reaction [Streptozocin results in increased expression of VCAM1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA] Streptozocin results in increased expression of VCAM1 mRNA; Streptozocin results in increased expression of VCAM1 protein [Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein; Curcumin analog inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]; sulforaphane inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of VCAM1 protein] |
CTD |
PMID:16129698 PMID:16139267 PMID:16979161 PMID:17589825 PMID:24707343 PMID:25199697 PMID:28700904 PMID:28946194 More...
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vcp |
valosin-containing protein |
multiple interactions increases expression |
EXP |
4-phenylbutyric acid inhibits the reaction [Streptozocin results in increased expression of VCP protein] |
CTD |
PMID:30980806 |
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NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
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G |
Vdac1 |
voltage-dependent anion channel 1 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of VDAC1 protein Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC1 protein] |
CTD |
PMID:19634143 |
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NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640
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G |
Vdac2 |
voltage-dependent anion channel 2 |
increases expression multiple interactions |
EXP |
Streptozocin results in increased expression of VDAC2 protein Trientine inhibits the reaction [Streptozocin results in increased expression of VDAC2 protein] |
CTD |
PMID:19634143 |
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NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553
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G |
Vdr |
vitamin D receptor |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of VDR mRNA; Streptozocin results in decreased expression of VDR protein Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR mRNA]; Calcitriol inhibits the reaction [Streptozocin results in decreased expression of VDR protein] |
CTD |
PMID:29953732 |
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NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions decreases expression increases expression decreases secretion |
ISO EXP |
bisphenol A inhibits the reaction [Streptozocin results in decreased secretion of VEGFA protein]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; dehydroxymethylepoxyquinomicin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Telmisartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA] [Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein; ACE2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; benazepril inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; cloricromen inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Curcumin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; manumycin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Melatonin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; PD 123319 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; procyanidin B2 inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Resveratrol inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Simvastatin inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Taurine inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; Thioctic Acid inhibits the reaction [Streptozocin results in decreased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; turmeric extract inhibits the reaction [Streptozocin results in increased expression of VEGFA protein]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA mRNA]; Valsartan inhibits the reaction [Streptozocin results in increased expression of VEGFA protein] Streptozocin results in increased expression of VEGFA mRNA; Streptozocin results in increased expression of VEGFA protein |
CTD |
PMID:11596663 PMID:14718351 PMID:15643138 PMID:17662242 PMID:17724226 PMID:18569938 PMID:19279317 PMID:20821229 PMID:20844835 PMID:22058332 PMID:22191573 PMID:25199697 PMID:25240712 PMID:26073000 PMID:32554039 PMID:35051763 More...
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vegfc |
vascular endothelial growth factor C |
decreases expression multiple interactions |
EXP |
Streptozocin results in decreased expression of VEGFC mRNA baicalin inhibits the reaction [Streptozocin results in decreased expression of VEGFC mRNA] |
CTD |
PMID:34414639 |
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NCBI chr16:37,712,251...37,827,845
Ensembl chr16:37,712,262...37,827,848
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G |
Vim |
vimentin |
multiple interactions increases expression |
EXP |
carvedilol inhibits the reaction [Streptozocin results in increased expression of VIM protein] |
CTD |
PMID:12140129 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Vldlr |
very low density lipoprotein receptor |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of VLDLR mRNA |
CTD |
PMID:29127188 |
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NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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G |
Vnn1 |
vanin 1 |
multiple interactions |
EXP |
[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA; dapagliflozin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA]; Metformin inhibits the reaction [[Streptozocin co-treated with Fructose] results in increased expression of VNN1 mRNA] |
CTD |
PMID:30551545 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Vwa3b |
von Willebrand factor A domain containing 3B |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in increased expression of VWA3B mRNA |
CTD |
PMID:33484791 |
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NCBI chr 9:39,249,523...39,419,614
Ensembl chr 9:39,250,430...39,419,611
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G |
Wdr31 |
WD repeat domain 31 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of WDR31 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 5:75,897,074...75,917,461
Ensembl chr 5:75,898,353...75,917,417
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G |
Wdr35 |
WD repeat domain 35 |
increases expression |
EXP |
Streptozocin results in increased expression of WDR35 mRNA |
CTD |
PMID:20224876 |
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NCBI chr 6:31,771,315...31,831,450
Ensembl chr 6:31,771,360...31,831,029
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G |
Wee1 |
WEE1 G2 checkpoint kinase |
increases expression |
EXP |
Streptozocin results in increased expression of WEE1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
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G |
Wnt3a |
Wnt family member 3A |
multiple interactions decreases expression |
ISO |
5-Methoxypsoralen inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein]; Tadalafil inhibits the reaction [Streptozocin results in decreased expression of WNT3A protein] |
CTD |
PMID:34428446 |
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NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324
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G |
Wsb1 |
WD repeat and SOCS box-containing 1 |
decreases expression |
EXP |
Streptozocin results in decreased expression of WSB1 mRNA |
CTD |
PMID:25905778 |
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NCBI chr10:64,202,761...64,219,039
Ensembl chr10:64,202,763...64,219,019
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
EXP ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form; Bilirubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of XBP1 mRNA alternative form]; moutan cortex inhibits the reaction [Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form]; Streptozocin results in increased expression of and results in increased secretion of XBP1 protein alternative form [Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA; NUS1 protein inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:27664441 PMID:33812996 PMID:37054934 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Xdh |
xanthine dehydrogenase |
multiple interactions affects activity increases expression increases activity |
EXP |
[Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased activity of XDH protein modified form; [Propolis co-treated with Chlorpyrifos co-treated with Streptozocin] results in increased expression of XDH mRNA; [Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; [Streptozocin co-treated with Chlorpyrifos] inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; [Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form; [Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA; Allopurinol inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Allopurinol inhibits the reaction [Streptozocin affects the activity of XDH protein]; Chlorpyrifos promotes the reaction [Streptozocin results in increased expression of XDH mRNA]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [[Streptozocin co-treated with Chlorpyrifos] results in increased expression of XDH mRNA]; Propolis inhibits the reaction [Streptozocin results in increased activity of XDH protein modified form]; Propolis inhibits the reaction [Streptozocin results in increased expression of XDH mRNA]; Quercetin inhibits the reaction [[Streptozocin affects the activity of XDH protein] which results in increased chemical synthesis of Hydrogen Peroxide]; Quercetin inhibits the reaction [Streptozocin affects the activity of XDH protein]; Streptozocin inhibits the reaction [Propolis results in decreased activity of XDH protein modified form]; Streptozocin inhibits the reaction [Propolis results in decreased expression of XDH mRNA]; Streptozocin promotes the reaction [Chlorpyrifos results in increased activity of XDH protein modified form]; Streptozocin promotes the reaction [Chlorpyrifos results in increased expression of XDH mRNA] Streptozocin results in increased activity of XDH protein; Streptozocin results in increased activity of XDH protein modified form |
CTD |
PMID:23647015 PMID:31400774 PMID:32812462 PMID:37354076 |
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NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
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G |
Xiap |
X-linked inhibitor of apoptosis |
increases expression |
EXP |
Streptozocin results in increased expression of XIAP protein |
CTD |
PMID:15976052 |
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NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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G |
Zdhhc23 |
zinc finger DHHC-type palmitoyltransferase 23 |
multiple interactions |
EXP |
[resveratrol co-treated with Streptozocin] results in decreased expression of ZDHHC23 mRNA |
CTD |
PMID:25905778 |
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NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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G |
Zeb2 |
zinc finger E-box binding homeobox 2 |
decreases expression multiple interactions |
ISO |
Streptozocin results in decreased expression of ZEB2 mRNA SOD1 protein inhibits the reaction [Streptozocin results in decreased expression of ZEB2 mRNA] |
CTD |
PMID:27629361 |
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NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157
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G |
Zfp184 |
zinc finger protein 184 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of ZFP184 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr17:42,588,140...42,603,905
Ensembl chr17:42,566,796...42,603,815
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G |
Zfp239 |
zinc finger protein 239 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA; Diethylhexyl Phthalate inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of ZFP239 mRNA] |
CTD |
PMID:33484791 |
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NCBI chr 4:151,029,431...151,039,283
Ensembl chr 4:151,029,405...151,039,529
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G |
Zpbp2 |
zona pellucida binding protein 2 |
multiple interactions |
ISO |
[Streptozocin co-treated with Dietary Fats co-treated with Diethylhexyl Phthalate] results in decreased expression of ZPBP2 mRNA |
CTD |
PMID:33484791 |
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NCBI chr10:83,558,772...83,567,511
Ensembl chr10:83,559,016...83,567,508
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