Nudt7 (nudix hydrolase 7) - Rat Genome Database

Name: Nudt7
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Nudt7 (nudix hydrolase 7) Rattus norvegicus

Analyze

Symbol:

Nudt7

Name:

nudix hydrolase 7

RGD ID:

1306719

Description:

Predicted to enable CoA pyrophosphatase activity; magnesium ion binding activity; and snoRNA binding activity. Predicted to be involved in purine nucleoside bisphosphate catabolic process. Predicted to act upstream of or within acetyl-CoA catabolic process and brown fat cell differentiation. Predicted to be located in peroxisome. Orthologous to human NUDT7 (nudix hydrolase 7); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',5-triiodo-L-thyronine.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC102555567; LOC361413; nudix (nucleoside diphosphate linked moiety X)-type motif 7; nudix motif 7; peroxisomal coenzyme A diphosphatase NUDT7; peroxisomal coenzyme A diphosphatase NUDT7-like

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NUDT7 (nudix hydrolase 7)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Nudt7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nudt7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NUDT7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NUDT7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nudt7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NUDT7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NUDT7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nudt7 (nudix hydrolase 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Nudt7 (nudix hydrolase 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	NUDT7 (nudix hydrolase 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nudt7 (nudix (nucleoside diphosphate linked moiety X)-type motif 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PCD1	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	ndx-8	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	nudt7	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	42,125,679 - 42,151,198 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	42,125,711 - 42,151,081 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	48,949,985 - 48,964,251 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	19	49,603,256 - 49,617,524 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	19	51,851,962 - 51,866,240 (+)	NCBI	Rnor_WKY
Rnor_6.0	19	46,455,745 - 46,470,070 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	46,455,761 - 46,482,050 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	57,278,677 - 57,293,046 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	44,181,782 - 44,196,976 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	19	41,436,677 - 41,450,937 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

genetic disease (ISO)

Liver Neoplasms (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2-acetamidofluorene (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,3',5-triiodo-L-thyronine (EXP)

4,4'-diaminodiphenylmethane (EXP)

4,4'-sulfonyldiphenol (ISO)

4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid (ISO)

4-amino-2,6-dinitrotoluene (EXP)

5-aza-2'-deoxycytidine (ISO)

acrylamide (ISO)

aflatoxin B1 (EXP,ISO)

aldrin (ISO)

all-trans-retinoic acid (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP)

cadmium dichloride (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

choline (ISO)

ciguatoxin CTX1B (ISO)

cisplatin (ISO)

clofibric acid (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

dicrotophos (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

epoxiconazole (ISO)

ethanol (ISO)

finasteride (EXP)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

genistein (EXP)

gentamycin (EXP)

hydralazine (ISO)

inulin (ISO)

L-methionine (ISO)

leflunomide (EXP)

methylmercury chloride (ISO)

monosodium L-glutamate (ISO)

N-nitrosodiethylamine (EXP,ISO)

nefazodone (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

nimesulide (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

parathion (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

pirinixic acid (EXP,ISO)

pregnenolone 16alpha-carbonitrile (ISO)

propiconazole (ISO)

resveratrol (ISO)

rotenone (ISO)

SB 431542 (ISO)

senecionine (ISO)

silicon dioxide (ISO)

sodium arsenate (ISO)

streptozocin (ISO)

sulforaphane (ISO)

temozolomide (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

Triptolide (ISO)

triptonide (ISO)

trovafloxacin (ISO)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acetyl-CoA catabolic process (ISO)

brown fat cell differentiation (ISO)

butyryl-CoA catabolic process (ISO)

coenzyme A catabolic process (IBA,ISO)

malonyl-CoA catabolic process (ISO)

medium-chain fatty-acyl-CoA catabolic process (ISO)

nucleoside diphosphate metabolic process (IEA)

propionyl-CoA catabolic process (ISO)

propionyl-CoA metabolic process (ISO)

succinyl-CoA catabolic process (ISO)

Cellular Component

peroxisome (ISO)

Molecular Function

5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity (ISO)

CoA pyrophosphatase activity (ISO)

magnesium ion binding (ISO)

manganese ion binding (IEA)

snoRNA binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:11415433	PMID:12790796	PMID:18492766	PMID:20178365	PMID:21070968

Genomics

Comparative Map Data

Nudt7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	19	42,125,679 - 42,151,198 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	19	42,125,711 - 42,151,081 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	19	48,949,985 - 48,964,251 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	19	49,603,256 - 49,617,524 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	19	51,851,962 - 51,866,240 (+)	NCBI	Rnor_WKY
Rnor_6.0	19	46,455,745 - 46,470,070 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	46,455,761 - 46,482,050 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	57,278,677 - 57,293,046 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	44,181,782 - 44,196,976 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	19	41,436,677 - 41,450,937 (+)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

NUDT7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	16	77,722,514 - 77,742,260 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	16	77,722,492 - 77,742,260 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	16	77,756,411 - 77,776,157 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	16	76,313,912 - 76,333,655 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	16	62,054,090 - 62,073,833 (+)	NCBI		Celera
Cytogenetic Map	16	q23.1	NCBI
HuRef	16	63,512,539 - 63,532,315 (+)	NCBI		HuRef
CHM1_1	16	79,167,909 - 79,187,677 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	16	83,778,636 - 83,798,355 (+)	NCBI		T2T-CHM13v2.0

Nudt7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	114,860,314 - 114,881,471 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	114,860,297 - 114,881,479 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	114,133,574 - 114,154,731 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	114,133,557 - 114,154,739 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	116,657,479 - 116,676,205 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	117,019,592 - 117,038,289 (+)	NCBI		MGSCv36	mm8
Celera	8	118,345,752 - 118,364,538 (+)	NCBI		Celera
Cytogenetic Map	8	E1	NCBI

Nudt7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955522	944,565 - 960,244 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955522	945,186 - 960,094 (+)	NCBI	ChiLan1.0	ChiLan1.0

NUDT7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	16	93,375,260 - 93,396,912 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	16	58,312,917 - 58,333,256 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	16	77,747,944 - 77,767,687 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	16	77,747,863 - 77,801,651 (+)	Ensembl	panpan1.1		panPan2

NUDT7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	73,515,819 - 73,527,780 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	73,516,166 - 73,527,716 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	73,463,629 - 73,475,592 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	73,822,491 - 73,834,439 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	73,822,818 - 73,834,399 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	73,762,630 - 73,774,557 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	73,598,591 - 73,610,719 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	74,082,829 - 74,094,799 (-)	NCBI		UU_Cfam_GSD_1.0

Nudt7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409349	33,496,220 - 33,509,844 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936475	26,079,275 - 26,089,889 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936475	26,079,298 - 26,095,466 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NUDT7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	10,158,688 - 10,173,980 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	10,161,959 - 10,174,006 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	10,102,285 - 10,114,189 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NUDT7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	5	63,212,163 - 63,231,465 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	5	63,212,226 - 63,231,650 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666047	12,817,483 - 12,836,766 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nudt7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624746	9,228,321 - 9,242,830 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624746	9,228,656 - 9,242,808 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nudt7
175 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	303
Count of miRNA genes:	194
Interacting mature miRNAs:	230
Transcripts:	ENSRNOT00000034012
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9589102	Slep13	Serum leptin concentration QTL 13	4.63	0.001	blood leptin amount (VT:0005667)	plasma leptin level (CMO:0000781)	19	569374	45569374	Rat
8694186	Bw152	Body weight QTL 152	3.34	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	569374	45569374	Rat
7247442	Uae39	Urinary albumin excretion QTL 39			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	2187927	46708701	Rat
724566	Uae12	Urinary albumin excretion QTL 12	5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	2187927	56457239	Rat
61447	Tcas1	Tongue tumor susceptibility QTL 1	6.08		tongue integrity trait (VT:0010553)	squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)	19	2316121	47316121	Rat
2317848	Alcrsp21	Alcohol response QTL 21	1.899999976158142	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	19	3204777	48204777	Rat
1331737	Uae29	Urinary albumin excretion QTL 29	5.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	19	4096155	55283277	Rat
724518	Uae19	Urinary albumin excretion QTL 19	5.5		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	19	7457249	42983518	Rat
61423	Cia14	Collagen induced arthritis QTL 14	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	19	10827970	43544039	Rat
7411549	Bw130	Body weight QTL 130	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	19	15455860	57337602	Rat
1331788	Rf45	Renal function QTL 45	2.818		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	19	15605023	46559041	Rat
1578764	Stresp19	Stress response QTL 19	3.6	0.001	blood renin amount (VT:0003349)	plasma renin activity level (CMO:0000116)	19	15630201	57337602	Rat
2298478	Eau8	Experimental allergic uveoretinitis QTL 8		0.0163	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	19	17154433	57337602	Rat
61350	Bp32	Blood pressure QTL 32		0.012	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	19	20483575	57337602	Rat
724546	Kidm3	Kidney mass QTL 3	3.1		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	19	29322490	57337602	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum insulin level (CMO:0000358)	19	33838214	55283146	Rat
1358200	Insglur2	Insulin/glucose ratio QTL 2	4.1		blood glucose amount (VT:0000188)	serum glucose level (CMO:0000543)	19	33838214	55283146	Rat

Markers in Region

D19Rat90

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	42,130,309 - 42,130,534 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	46,460,372 - 46,460,596	NCBI	Rnor6.0
Rnor_5.0	19	57,283,283 - 57,283,507	UniSTS	Rnor5.0
RGSC_v3.4	19	44,186,387 - 44,186,608	RGD	RGSC3.4
RGSC_v3.4	19	44,186,388 - 44,186,612	UniSTS	RGSC3.4
RGSC_v3.1	19	44,191,268 - 44,191,489	RGD
Celera	19	41,441,228 - 41,441,452	UniSTS
RH 3.4 Map	19	554.8	RGD
RH 3.4 Map	19	554.8	UniSTS
RH 2.0 Map	19	570.4	RGD
FHH x ACI Map	19	33.46	RGD
Cytogenetic Map	19	q12	UniSTS

RH130335

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	42,139,774 - 42,139,994 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	46,469,826 - 46,470,045	NCBI	Rnor6.0
Rnor_5.0	19	57,292,798 - 57,293,017	UniSTS	Rnor5.0
RGSC_v3.4	19	44,196,728 - 44,196,947	UniSTS	RGSC3.4
Celera	19	41,450,693 - 41,450,912	UniSTS
RH 3.4 Map	19	549.7	UniSTS
Cytogenetic Map	19	q12	UniSTS

RH133169

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	19	42,138,386 - 42,138,602 (+)	MAPPER	mRatBN7.2
Rnor_6.0	19	46,468,450 - 46,468,665	NCBI	Rnor6.0
Rnor_5.0	19	57,291,361 - 57,291,576	UniSTS	Rnor5.0
RGSC_v3.4	19	44,194,466 - 44,194,681	UniSTS	RGSC3.4
Celera	19	41,449,303 - 41,449,518	UniSTS
RH 3.4 Map	19	586.3	UniSTS
Cytogenetic Map	19	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1	29	22	18	4	18	8	11	10	31	20	3	8
Low	2	14	35	23	15	23			64	4	20	8
Below cutoff											1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001305426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001305427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006255677	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601319	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601320	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017601321	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097863	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097865	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039097867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CB582462	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM098914	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM122430	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM141049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000034012 ⟹ ENSRNOP00000032779

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	42,125,711 - 42,140,014 (+)	Ensembl
Rnor_6.0 Ensembl	19	46,455,761 - 46,470,070 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093238 ⟹ ENSRNOP00000076192

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	42,125,752 - 42,140,019 (+)	Ensembl
Rnor_6.0 Ensembl	19	46,455,878 - 46,469,625 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093392 ⟹ ENSRNOP00000076103

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	19	42,125,752 - 42,151,081 (+)	Ensembl
Rnor_6.0 Ensembl	19	46,455,859 - 46,482,050 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093714 ⟹ ENSRNOP00000076259

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	19	46,465,647 - 46,466,119 (+)	Ensembl

RefSeq Acc Id:

NM_001305426 ⟹ NP_001292355

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,125,759 - 42,140,019 (+)	NCBI
Rnor_6.0	19	46,455,823 - 46,470,070 (+)	NCBI
Celera	19	41,436,677 - 41,450,937 (+)	NCBI

Sequence:

show sequence

CCGAAGTCTCCAGCCGCTTGTAGGAAAGGTACAGCAGGGCCGATGCCGCGACCTTGTGGACTCC
AGGAGTCTGTCAGAAACAATCTGATTGACGATGCCAAGGCTCGCTTGAAAAAGTTTGATGTTGG
GACCAGATATTCCCACTTGTCCCCTAGTAAGTATTCTGTTCTTCTGCCATTGCTGGCCAGAGGA
GAAAAGCTGTACTTGCTGTTCACGGTCCGCTCAGACAAGCTGAGAAGGGCACCTGGAGAAGTCT
GCTTCCCTGGAGGAAAGAGGGACCCAGTGGATGCAGATGACACAGCGACTGCTCTCCGTGAAGC
CCAGGAGGAGGTGGGGCTGCATCCCCACCAAGTGGAGGTGGTCTCTCACCTGGTGCCATATTTT
ATTAATAACAATGACCTGGTAACGCCCGTAGTGGGATTTCTAGACCCCGACTTCCAGGCCCAGC
CTAATGCTGATGAAGTGAAGGATGTGTTCCTCGTGCCTTTGGACTATTTCCTCTGTCCCCAAGT
CTACTACCAGAGTCACTTCACACATTCTGGCTACCATTTTGTTTTGCATTGCTTTGAATACACA
GACCCTGAGACTGGCTCGAAGTACCTCATCAAGGGAATGACCTCAAAATTGGCTGTGCTGGCTG
CCTTAATTATTTTTGAAAAAAGTCCTTCCTTCGAGACCGAATTTGATCTCCATGACCTGATACC
ATCTTGTGAGAAGACCTTTCTTCATAGATGTTCTTCCAGCAAATTGTGAAGTCACCGAAACCCA
AAAGAACATACACGAGGTTTTTGCATGAGCTTATGCTCAGAACAGCAGCATTAGCGAGTGGTAT
CTGACAGGTGTGAATATATTTCGTACACCGTGATTGTGAGGGCCTTACCTGGTTTCCAGTAGCC
AATTTTTCACCTTGAACACTATAAGTCTTTCAGAACTGGAAAAAAAAGCACGAGCAGGGTAGTC
TAATTTTACCCATTAAAATGTCGCTATTTTTAGTTGTTTTATGGGTGTCTGTCACATAGTAGGC
ACTTAATAAATATTTGTCAAATATAA

hide sequence

RefSeq Acc Id:

NM_001305427 ⟹ NP_001292356

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,125,759 - 42,140,019 (+)	NCBI
Rnor_6.0	19	46,455,823 - 46,470,070 (+)	NCBI
Celera	19	41,436,677 - 41,450,937 (+)	NCBI

Sequence:

show sequence

CCGAAGTCTCCAGCCGCTTGTAGGAAAGGTACAGCAGGGCCGATGCCGCGACCTTGTGGACTCC
AGGAGTCTGTCAGAAACAATCTGATTGACGATGCCAAGGCTCGCTTGAAAAAGTTTGATGTTGG
GACCAGATATTCCCACTTGTCCCCTAGTAAGTATTCTGTTCTTCTGCCATTGCTGGCCAGAGGA
GAAAAGCTGTACTTGCTGTTCACGGTCCGCTCAGACAAGAATCAACCTGGATGGCTATCGGAGA
AGGAATGGATCAGGAAAAATGTAAGCTGAGAAGGGCACCTGGAGAAGTCTGCTTCCCTGGAGGA
AAGAGGGACCCAGTGGATGCAGATGACACAGCGACTGCTCTCCGTGAAGCCCAGGAGGAGGTGG
GGCTGCATCCCCACCAAGTGGAGGTGGTCTCTCACCTGGTGCCATATTTTATTAATAACAATGA
CCTGGTAACGCCCGTAGTGGGATTTCTAGACCCCGACTTCCAGGCCCAGCCTAATGCTGATGAA
GTGAAGGATGTGTTCCTCGTGCCTTTGGACTATTTCCTCTGTCCCCAAGTCTACTACCAGAGTC
ACTTCACACATTCTGGCTACCATTTTGTTTTGCATTGCTTTGAATACACAGACCCTGAGACTGG
CTCGAAGTACCTCATCAAGGGAATGACCTCAAAATTGGCTGTGCTGGCTGCCTTAATTATTTTT
GAAAAAAGTCCTTCCTTCGAGACCGAATTTGATCTCCATGACCTGATACCATCTTGTGAGAAGA
CCTTTCTTCATAGATGTTCTTCCAGCAAATTGTGAAGTCACCGAAACCCAAAAGAACATACACG
AGGTTTTTGCATGAGCTTATGCTCAGAACAGCAGCATTAGCGAGTGGTATCTGACAGGTGTGAA
TATATTTCGTACACCGTGATTGTGAGGGCCTTACCTGGTTTCCAGTAGCCAATTTTTCACCTTG
AACACTATAAGTCTTTCAGAACTGGAAAAAAAAGCACGAGCAGGGTAGTCTAATTTTACCCATT
AAAATGTCGCTATTTTTAGTTGTTTTATGGGTGTCTGTCACATAGTAGGCACTTAATAAATATT
TGTCAAATATAA

hide sequence

RefSeq Acc Id:

XM_017601321 ⟹ XP_017456810

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,125,679 - 42,140,019 (+)	NCBI
Rnor_6.0	19	46,455,747 - 46,470,070 (+)	NCBI

Sequence:

show sequence

CTCTCCTCCCGCAGAGTCCCCGCCCTCACTCCCGGCTGGGGCTACAATGCGCGTGCGCGTCAGA
ACTCGTTGCTTCCCGAAGTCTCCAGCCGCTTGTAGGAAAGGTACAGCAGGGCCGATGCCGCGAC
CTTGTGGACTCCAGGAGTCTGTCAGAAACAATCTGATTGACGATGCCAAGGCTCGCTTGAAAAA
GTTTGATGTTGGGACCAGATATTCCCACTTGTCCCCTAGTAAGTATTCTGTTCTTCTGCCATTG
CTGGCCAGAGGAGAAAAGCTGTACTTGCTGTTCACGGTCCGCTCAGACAAGCTGAGAAGGGCAC
CTGGAGAAGTCTGCTTCCCTGGAGGAAAGAGGGACCCAGTGGATGCAGATGACACAGCGACTGC
TCTCCGTGAAGCCCAGGAGGAGAACAATGACCTGGTAACGCCCGTAGTGGGATTTCTAGACCCC
GACTTCCAGGCCCAGCCTAATGCTGATGAAGTGAAGGATGTGTTCCTCGTGCCTTTGGACTATT
TCCTCTGTCCCCAAGTCTACTACCAGAGTCACTTCACACATTCTGGCTACCATTTTGTTTTGCA
TTGCTTTGAATACACAGACCCTGAGACTGGCTCGAAGTACCTCATCAAGGGAATGACCTCAAAA
TTGGCTGTGCTGGCTGCCTTAATTATTTTTGAAAAAAGTCCTTCCTTCGAGACCGAATTTGATC
TCCATGACCTGATACCATCTTGTGAGAAGACCTTTCTTCATAGATGTTCTTCCAGCAAATTGTG
AAGTCACCGAAACCCAAAAGAACATACACGAGGTTTTTGCATGAGCTTATGCTCAGAACAGCAG
CATTAGCGAGTGGTATCTGACAGGTGTGAATATATTTCGTACACCGTGATTGTGAGGGCCTTAC
CTGGTTTCCAGTAGCCAATTTTTCACCTTGAACACTATAAGTCTTTCAGAACTGGAAAAAAAAG
CACGAGCAGGGTAGTCTAATTTTACCCATTAAAATGTCGCTATTTTTAGTTGTTTTATGGGTGT
CTGTCACATAGTAGGCACTTAATAAATATTTGTCAAATATAA

hide sequence

RefSeq Acc Id:

XM_039097863 ⟹ XP_038953791

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,125,679 - 42,140,019 (+)	NCBI

RefSeq Acc Id:

XM_039097864 ⟹ XP_038953792

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,128,743 - 42,140,019 (+)	NCBI

RefSeq Acc Id:

XM_039097865 ⟹ XP_038953793

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,128,743 - 42,140,019 (+)	NCBI

RefSeq Acc Id:

XM_039097866 ⟹ XP_038953794

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,128,743 - 42,140,019 (+)	NCBI

RefSeq Acc Id:

XM_039097867 ⟹ XP_038953795

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	19	42,125,679 - 42,151,198 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001292355	(Get FASTA)	NCBI Sequence Viewer
	NP_001292356	(Get FASTA)	NCBI Sequence Viewer
	XP_017456810	(Get FASTA)	NCBI Sequence Viewer
	XP_038953791	(Get FASTA)	NCBI Sequence Viewer
	XP_038953792	(Get FASTA)	NCBI Sequence Viewer
	XP_038953793	(Get FASTA)	NCBI Sequence Viewer
	XP_038953794	(Get FASTA)	NCBI Sequence Viewer
	XP_038953795	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL92614	(Get FASTA)	NCBI Sequence Viewer
	EDL92615	(Get FASTA)	NCBI Sequence Viewer
	EDL92616	(Get FASTA)	NCBI Sequence Viewer
	EDL92617	(Get FASTA)	NCBI Sequence Viewer
	EDL92618	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001292356 ⟸ NM_001305427
- Peptide Label:	isoform 2
- Sequence:	show sequence MAIGEGMDQEKCKLRRAPGEVCFPGGKRDPVDADDTATALREAQEEVGLHPHQVEVVSHLVPYF INNNDLVTPVVGFLDPDFQAQPNADEVKDVFLVPLDYFLCPQVYYQSHFTHSGYHFVLHCFEYT DPETGSKYLIKGMTSKLAVLAALIIFEKSPSFETEFDLHDLIPSCEKTFLHRCSSSKL hide sequence

RefSeq Acc Id:

NP_001292355 ⟸ NM_001305426

- Peptide Label:

isoform 1

- Sequence:

show sequence

MPRPCGLQESVRNNLIDDAKARLKKFDVGTRYSHLSPSKYSVLLPLLARGEKLYLLFTVRSDKL
RRAPGEVCFPGGKRDPVDADDTATALREAQEEVGLHPHQVEVVSHLVPYFINNNDLVTPVVGFL
DPDFQAQPNADEVKDVFLVPLDYFLCPQVYYQSHFTHSGYHFVLHCFEYTDPETGSKYLIKGMT
SKLAVLAALIIFEKSPSFETEFDLHDLIPSCEKTFLHRCSSSKL

hide sequence

RefSeq Acc Id:

XP_017456810 ⟸ XM_017601321

- Peptide Label:

isoform X3

- Sequence:

show sequence

MRVRVRTRCFPKSPAACRKGTAGPMPRPCGLQESVRNNLIDDAKARLKKFDVGTRYSHLSPSKY
SVLLPLLARGEKLYLLFTVRSDKLRRAPGEVCFPGGKRDPVDADDTATALREAQEENNDLVTPV
VGFLDPDFQAQPNADEVKDVFLVPLDYFLCPQVYYQSHFTHSGYHFVLHCFEYTDPETGSKYLI
KGMTSKLAVLAALIIFEKSPSFETEFDLHDLIPSCEKTFLHRCSSSKL

hide sequence

RefSeq Acc Id:

ENSRNOP00000032779 ⟸ ENSRNOT00000034012

RefSeq Acc Id:

ENSRNOP00000076259 ⟸ ENSRNOT00000093714

RefSeq Acc Id:

ENSRNOP00000076103 ⟸ ENSRNOT00000093392

RefSeq Acc Id:

ENSRNOP00000076192 ⟸ ENSRNOT00000093238

RefSeq Acc Id:	XP_038953795 ⟸ XM_039097867
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_038953791 ⟸ XM_039097863
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038953792 ⟸ XM_039097864
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038953793 ⟸ XM_039097865
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_038953794 ⟸ XM_039097866
- Peptide Label:	isoform X5

Protein Domains

Nudix hydrolase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZV74-F1-model_v2	AlphaFold	D3ZV74	1-260	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13701168

Promoter ID:

EPDNEW_R11685

Type:

initiation region

Name:

Nudt7_1

Description:

nudix hydrolase 7

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	19	46,455,808 - 46,455,868	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306719	AgrOrtholog
BioCyc Gene	G2FUF-5599	BioCyc
Ensembl Genes	ENSRNOG00000011976	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000032779	ENTREZGENE
	ENSRNOP00000032779.6	UniProtKB/TrEMBL
	ENSRNOP00000076103.2	UniProtKB/TrEMBL
	ENSRNOP00000076192	ENTREZGENE
	ENSRNOP00000076192.2	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034012	ENTREZGENE
	ENSRNOT00000034012.7	UniProtKB/TrEMBL
	ENSRNOT00000093238	ENTREZGENE
	ENSRNOT00000093238.2	UniProtKB/TrEMBL
	ENSRNOT00000093392.2	UniProtKB/TrEMBL
Gene3D-CATH	Nucleoside Triphosphate Pyrophosphohydrolase	UniProtKB/TrEMBL
InterPro	CoAse	UniProtKB/TrEMBL
	NUDIX_hydrolase_dom	UniProtKB/TrEMBL
	NUDIX_hydrolase_dom-like	UniProtKB/TrEMBL
	NUDIX_hydrolase_NudL_CS	UniProtKB/TrEMBL
NCBI Gene	361413	ENTREZGENE
PANTHER	PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7	UniProtKB/TrEMBL
	PTHR12992	UniProtKB/TrEMBL
Pfam	NUDIX	UniProtKB/TrEMBL
PhenoGen	Nudt7	PhenoGen
PROSITE	NUDIX	UniProtKB/TrEMBL
	NUDIX_COA	UniProtKB/TrEMBL
Superfamily-SCOP	NUDIX_hydrolase	UniProtKB/TrEMBL
UniProt	A0A1W2Q618_RAT	UniProtKB/TrEMBL
	A0A1W2Q6B7_RAT	UniProtKB/TrEMBL
	D3ZV74_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-10	Nudt7	nudix hydrolase 7	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-01-14	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	LOC102555567	peroxisomal coenzyme A diphosphatase NUDT7-like	Data Merged	737654	APPROVED
2013-12-18	LOC102555567	peroxisomal coenzyme A diphosphatase NUDT7-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-30	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	Nudt7_predicted	nudix (nucleoside diphosphate linked moiety X)-type motif 7 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Nudt7_predicted	nudix (nucleoside diphosphate linked moiety X)-type motif 7 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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