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Gene: Ass1 (argininosuccinate synthase 1) Rattus norvegicus
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Symbol: Ass1
Name: argininosuccinate synthase 1
Description: Exhibits argininosuccinate synthase activity and toxic substance binding activity. Involved in several processes, including cellular amino acid metabolic process; cellular response to lipid; and cellular response to organonitrogen compound. Localizes to the cell body fiber; intracellular membrane-bounded organelle; and perikaryon. Biomarker of uveitis. Human ortholog(s) of this gene implicated in citrullinemia; hepatocellular carcinoma; and melanoma. Orthologous to human ASS1 (argininosuccinate synthase 1); PARTICIPATES IN urea cycle pathway; AGAT deficiency pathway; arginine and proline metabolic pathway; INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: argininosuccinate synthase; argininosuccinate synthetase; argininosuccinate synthetase 1; arginosuccinate synthetase; arginosuccinate synthetase 1; Ass; ASSA; citrulline--aspartate ligase
Orthologs:
Homo sapiens (human) : ASS1 (argininosuccinate synthase 1)  HGNC  Alliance
Mus musculus (house mouse) : Ass1 (argininosuccinate synthetase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ass1 (argininosuccinate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ASS1 (argininosuccinate synthase 1)
Canis lupus familiaris (dog) : ASS1 (argininosuccinate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ass1 (argininosuccinate synthase 1)
Sus scrofa (pig) : ASS1 (argininosuccinate synthase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0310,327,411 - 10,375,847 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0315,686,773 - 15,735,199 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4310,578,717 - 10,622,332 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1310,469,450 - 10,523,821 (+)NCBI
Celera39,506,506 - 9,549,757 (+)NCBICelera
Cytogenetic Map3p12NCBI
RH 3.4 Map351.4RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ass1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2163
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.