Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ass1 (argininosuccinate synthetase 1) Mus musculus
Analyze
Symbol: Ass1
Name: argininosuccinate synthetase 1
Description: Predicted to have several functions, including argininosuccinate synthase activity; identical protein binding activity; and toxic substance binding activity. Involved in circadian rhythm. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; integumental system; metanephros; and sensory organ. Used to study citrullinemia. Human ortholog(s) of this gene implicated in citrullinemia; classic citrullinemia; hepatocellular carcinoma; and melanoma. Orthologous to human ASS1 (argininosuccinate synthase 1); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; INTERACTS WITH (+)-dexrazoxane; 17beta-estradiol; 2,3,7,8-tetrabromodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408052; argininosuccinate synthase; arginosuccinate synthetase 1; ASS; Ass-1; citrulline--aspartate ligase; fold; MGC103151
Orthologs:
Homo sapiens (human) : ASS1 (argininosuccinate synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ass1 (argininosuccinate synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ass1 (argininosuccinate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ASS1 (argininosuccinate synthase 1)
Canis lupus familiaris (dog) : ASS1 (argininosuccinate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ass1 (argininosuccinate synthase 1)
Sus scrofa (pig) : ASS1 (argininosuccinate synthase 1)
Chlorocebus sabaeus (African green monkey) : ASS1 (argininosuccinate synthase 1)
Heterocephalus glaber (naked mole-rat) : Ass1 (argininosuccinate synthase 1)
more info ...
Related Pseudogenes: Ass-ps1   Gm5424  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl231,470,207 - 31,520,672 (+)EnsemblGRCm38mm10GRCm38
GRCm38231,470,270 - 31,520,670 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37231,325,790 - 31,376,190 (+)NCBIGRCm37mm9NCBIm37
MGSCv36231,292,279 - 31,342,679 (+)NCBImm8
Celera231,171,177 - 31,221,646 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ass1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736137
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.