Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Ass1 (argininosuccinate synthetase 1) Mus musculus
Symbol: Ass1
Name: argininosuccinate synthetase 1
Description: Predicted to have several functions, including argininosuccinate synthase activity; identical protein binding activity; and toxic substance binding activity. Involved in circadian rhythm. Localizes to mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; integumental system; metanephros; and sensory organ. Used to study citrullinemia. Human ortholog(s) of this gene implicated in citrullinemia; classic citrullinemia; hepatocellular carcinoma; and melanoma. Orthologous to human ASS1 (argininosuccinate synthase 1); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; INTERACTS WITH (+)-dexrazoxane; 17beta-estradiol; 2,3,7,8-tetrabromodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408052; argininosuccinate synthase; arginosuccinate synthetase 1; ASS; Ass-1; citrulline--aspartate ligase; fold; MGC103151
Homo sapiens (human) : ASS1 (argininosuccinate synthase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ass1 (argininosuccinate synthase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ass1 (argininosuccinate synthase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ASS1 (argininosuccinate synthase 1)
Canis lupus familiaris (dog) : ASS1 (argininosuccinate synthase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ass1 (argininosuccinate synthase 1)
Sus scrofa (pig) : ASS1 (argininosuccinate synthase 1)
Chlorocebus sabaeus (African green monkey) : ASS1 (argininosuccinate synthase 1)
Heterocephalus glaber (naked mole-rat) : Ass1 (argininosuccinate synthase 1)
more info ...
Related Pseudogenes: Ass-ps1   Gm5424  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl231,470,207 - 31,520,672 (+)EnsemblGRCm38mm10GRCm38
GRCm38231,470,270 - 31,520,670 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37231,325,790 - 31,376,190 (+)NCBIGRCm37mm9NCBIm37
MGSCv36231,292,279 - 31,342,679 (+)NCBImm8
Celera231,171,177 - 31,221,646 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ass1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736137
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.