Gspt1 (G1 to S phase transition 1) - Rat Genome Database

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Gene: Gspt1 (G1 to S phase transition 1) Rattus norvegicus
Analyze
Symbol: Gspt1
Name: G1 to S phase transition 1
RGD ID: 2751
Description: Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in cytoplasmic translational termination and regulation of translational termination. Predicted to act upstream of or within protein methylation. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Orthologous to human GSPT1 (G1 to S phase transition 1); PARTICIPATES IN translation termination pathway; mRNA decay pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: eukaryotic peptide chain release factor GTP-binding subunit ERF3A; eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like; G1 to phase transition 1; G1 to S phase transition protein 1; G1-to-S phase transition 1; LOC100911685; MGC94063
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2104,362,528 - 4,397,215 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl104,312,863 - 4,446,200 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0104,313,100 - 4,347,661 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0103,179,171 - 3,213,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,249,196 - 4,283,833 (+)NCBIRGSC3.4rn4RGSC3.4
Celera103,386,388 - 3,421,025 (+)NCBICelera
Cytogenetic Map10q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
5-fluorouracil  (ISO)
aldehydo-D-glucosamine  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP)
bisphenol F  (ISO)
bortezomib  (ISO)
buspirone  (EXP)
cadmium atom  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
chromium(6+)  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
metformin  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-nitrosodiethylamine  (ISO)
nickel atom  (ISO)
ochratoxin A  (EXP)
paracetamol  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vincristine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1300226   PMID:15326224   PMID:18539146   PMID:22658674   PMID:22871113   PMID:30682371  


Genomics

Comparative Map Data
Gspt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2104,362,528 - 4,397,215 (+)NCBImRatBN7.2
Rnor_6.0 Ensembl104,312,863 - 4,446,200 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0104,313,100 - 4,347,661 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0103,179,171 - 3,213,732 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,249,196 - 4,283,833 (+)NCBIRGSC3.4rn4RGSC3.4
Celera103,386,388 - 3,421,025 (+)NCBICelera
Cytogenetic Map10q11NCBI
GSPT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1611,868,128 - 11,916,082 (-)EnsemblGRCh38hg38GRCh38
GRCh381611,868,128 - 11,916,654 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371611,961,985 - 12,010,511 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361611,874,040 - 11,917,309 (-)NCBINCBI36hg18NCBI36
Build 341611,874,039 - 11,917,309NCBI
Celera1612,136,295 - 12,184,521 (-)NCBI
Cytogenetic Map16p13.13NCBI
HuRef1611,878,684 - 11,927,176 (-)NCBIHuRef
CHM1_11611,962,002 - 12,010,568 (-)NCBICHM1_1
Gspt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391611,034,104 - 11,072,189 (-)NCBIGRCm39mm39
GRCm39 Ensembl1611,037,156 - 11,072,189 (-)Ensembl
GRCm381611,216,240 - 11,254,325 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1611,219,292 - 11,254,325 (-)EnsemblGRCm38mm10GRCm38
MGSCv371611,216,333 - 11,254,418 (-)NCBIGRCm37mm9NCBIm37
MGSCv361611,133,977 - 11,167,574 (-)NCBImm8
Celera1611,847,904 - 11,885,863 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map166.38NCBI
Gspt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554426,704,573 - 6,740,207 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554426,704,272 - 6,740,207 (+)NCBIChiLan1.0ChiLan1.0
GSPT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11612,031,243 - 12,057,794 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01610,807,248 - 10,854,698 (-)NCBIMhudiblu_PPA_v0panPan3
GSPT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1630,931,937 - 30,971,699 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl630,933,398 - 30,967,476 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha632,312,804 - 32,352,081 (+)NCBI
ROS_Cfam_1.0631,109,408 - 31,149,538 (+)NCBI
UMICH_Zoey_3.1630,923,766 - 30,963,908 (+)NCBI
UNSW_CanFamBas_1.0630,798,059 - 30,838,371 (+)NCBI
UU_Cfam_GSD_1.0631,221,314 - 31,261,658 (+)NCBI
Gspt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,783,470 - 111,818,051 (-)NCBI
SpeTri2.0NW_0049365309,628,905 - 9,663,491 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GSPT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl331,237,105 - 31,273,867 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1331,237,155 - 31,273,832 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GSPT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1511,335,211 - 11,382,904 (-)NCBI
ChlSab1.1 Ensembl511,340,187 - 11,382,310 (-)Ensembl
Vero_WHO_p1.0NW_02366606818,763,074 - 18,811,569 (+)NCBI
Gspt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247826,411,591 - 6,446,182 (+)NCBI

Position Markers
RH133814  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2104,362,126 - 4,362,333 (+)MAPPERmRatBN7.2
Rnor_6.0104,411,123 - 4,411,329NCBIRnor6.0
Rnor_6.0104,312,651 - 4,312,857NCBIRnor6.0
Rnor_5.0103,178,722 - 3,178,928UniSTSRnor5.0
Rnor_5.0103,277,052 - 3,277,258UniSTSRnor5.0
RGSC_v3.4104,248,747 - 4,248,953UniSTSRGSC3.4
Celera103,385,939 - 3,386,145UniSTS
Cytogenetic Map10q11UniSTS
WI-19180  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2104,396,780 - 4,397,013 (+)MAPPERmRatBN7.2
Rnor_6.0104,445,775 - 4,446,007NCBIRnor6.0
Rnor_6.0104,347,227 - 4,347,459NCBIRnor6.0
Rnor_5.0103,213,298 - 3,213,530UniSTSRnor5.0
Rnor_5.0103,311,704 - 3,311,936UniSTSRnor5.0
RGSC_v3.4104,283,399 - 4,283,631UniSTSRGSC3.4
Celera103,420,591 - 3,420,823UniSTS
Cytogenetic Map10q11UniSTS
RH128035  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2104,396,936 - 4,397,138 (+)MAPPERmRatBN7.2
Rnor_6.0104,445,931 - 4,446,132NCBIRnor6.0
Rnor_6.0104,347,383 - 4,347,584NCBIRnor6.0
Rnor_5.0103,213,454 - 3,213,655UniSTSRnor5.0
Rnor_5.0103,311,860 - 3,312,061UniSTSRnor5.0
RGSC_v3.4104,283,555 - 4,283,756UniSTSRGSC3.4
Celera103,420,747 - 3,420,948UniSTS
Cytogenetic Map10q11UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7387235Uae41Urinary albumin excretion QTL 415.260.1874urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)10129592136Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135538813Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138594330Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142669970Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)10144902893Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1076442166221621Rat
1549898Neuinf3Neuroinflammation QTL 326.4nervous system integrity trait (VT:0010566)MHC Class II RT1A-positive spinal cord ventral horn area to total spinal cord ventral horn area ratio (CMO:0001980)1028476255460218Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:36
Count of miRNA genes:36
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000003213
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 2 41 55 39 19 39 8 9 72 34 41 10 8
Below cutoff 1 2 2 2 2 2 2 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000003213   ⟹   ENSRNOP00000003213
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl104,411,766 - 4,445,769 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000074487   ⟹   ENSRNOP00000067103
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl104,313,100 - 4,347,659 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000091610   ⟹   ENSRNOP00000071846
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl104,312,863 - 4,446,200 (+)Ensembl
RefSeq Acc Id: NM_001003978   ⟹   NP_001003978
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2104,362,576 - 4,397,215 (+)NCBI
Rnor_6.0104,313,100 - 4,347,661 (+)NCBI
Rnor_5.0103,179,171 - 3,213,732 (+)NCBI
RGSC_v3.4104,249,196 - 4,283,833 (+)RGD
Celera103,386,388 - 3,421,025 (+)RGD
Sequence:
RefSeq Acc Id: XM_017596996   ⟹   XP_017452485
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2104,362,528 - 4,397,187 (+)NCBI
Rnor_6.0104,313,294 - 4,347,644 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001003978 (Get FASTA)   NCBI Sequence Viewer  
  XP_017452485 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH79092 (Get FASTA)   NCBI Sequence Viewer  
  AAN39139 (Get FASTA)   NCBI Sequence Viewer  
  EDL96197 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001003978   ⟸   NM_001003978
- UniProtKB: Q6AYD5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452485   ⟸   XM_017596996
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000067103   ⟸   ENSRNOT00000074487
RefSeq Acc Id: ENSRNOP00000003213   ⟸   ENSRNOT00000003213
RefSeq Acc Id: ENSRNOP00000071846   ⟸   ENSRNOT00000091610
Protein Domains
tr-type G

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2751 AgrOrtholog
  RGD:6491148 AgrOrtholog
Ensembl Genes ENSRNOG00000046271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000003213 UniProtKB/TrEMBL
  ENSRNOP00000067103 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000071846 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003213 UniProtKB/TrEMBL
  ENSRNOT00000074487 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000091610 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7123818 IMAGE-MGC_LOAD
InterPro Ataxin-2_C UniProtKB/TrEMBL
  G_TR_CS UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  ProtSyn_GTP_bd UniProtKB/TrEMBL
  Transl_elong_EF1A/Init_IF2_C UniProtKB/TrEMBL
  Transl_elong_EFTu/EF1A_2 UniProtKB/TrEMBL
  Transl_elong_EFTu/EF1A_C UniProtKB/TrEMBL
  Transl_elong_init/rib_B-barrel UniProtKB/TrEMBL
KEGG Report rno:24420 UniProtKB/TrEMBL
MGC_CLONE MGC:94063 IMAGE-MGC_LOAD
NCBI Gene 24420 ENTREZGENE
Pfam GTP_EFTU UniProtKB/TrEMBL
  GTP_EFTU_D2 UniProtKB/TrEMBL
  GTP_EFTU_D3 UniProtKB/TrEMBL
  PAM2 UniProtKB/TrEMBL
PhenoGen Gspt1 PhenoGen
PRINTS ELONGATNFCT UniProtKB/TrEMBL
PROSITE EFACTOR_GTP UniProtKB/TrEMBL
  G_TR_2 UniProtKB/TrEMBL
Superfamily-SCOP Elong_init_C UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
  Translat_factor UniProtKB/TrEMBL
UniProt Q6AYD5 ENTREZGENE, UniProtKB/TrEMBL
  Q812C3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Gspt1  G1 to S phase transition 1  LOC100911685  eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like  Data Merged 737654 PROVISIONAL
2012-07-05 LOC100911685  eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Gspt1  G1-to-S phase transition 1      Symbol and Name status set to approved 70586 APPROVED