Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sucla2 | Rat | obesity | | ISO | SUCLA2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:20882379 | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sucla2 | Rat | obesity | | ISO | SUCLA2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:20882379 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Mitochondrial GTP regulates glucose-stimulated insulin secretion. | Kibbey RG, etal., Cell Metab. 2007 Apr;5(4):253-64. |
4. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
5. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
6. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
7. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:8889548 | PMID:10727444 | PMID:11596118 | PMID:12477932 | PMID:12947022 | PMID:14651853 | PMID:17634366 | PMID:18614015 | PMID:19056867 | PMID:20833797 | PMID:25931508 |
Sucla2 (Rattus norvegicus - Norway rat) |
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SUCLA2 (Homo sapiens - human) |
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Sucla2 (Mus musculus - house mouse) |
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Sucla2 (Chinchilla lanigera - long-tailed chinchilla) |
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SUCLA2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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SUCLA2 (Canis lupus familiaris - dog) |
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Sucla2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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SUCLA2 (Sus scrofa - pig) |
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SUCLA2 (Chlorocebus sabaeus - green monkey) |
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Sucla2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Sucla2
367 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH141159 |
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BE101893 |
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RH139628 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_001108387 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
GenBank Nucleotide | BC166998 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
BF408124 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BF412750 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CF110427 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473951 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CO399305 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CR755094 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ216292 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000015 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000065195 ⟹ ENSRNOP00000060229 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000094835 ⟹ ENSRNOP00000084737 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001108387 ⟹ NP_001101857 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
Protein RefSeqs | NP_001101857 | (Get FASTA) | NCBI Sequence Viewer |
GenBank Protein | AAI66998 | (Get FASTA) | NCBI Sequence Viewer |
EDM02272 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000060229.1 | ||
ENSRNOP00000084737.1 |
RefSeq Acc Id: | NP_001101857 ⟸ NM_001108387 |
- UniProtKB: | F1LM47 (UniProtKB/TrEMBL), B2RZ24 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000060229 ⟸ ENSRNOT00000065195 |
Ensembl Acc Id: | ENSRNOP00000084737 ⟸ ENSRNOT00000094835 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-F1LM47-F1-model_v2 | AlphaFold | F1LM47 | 1-465 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13699825 | ||||||||
Promoter ID: | EPDNEW_R10349 | ||||||||
Type: | initiation region | ||||||||
Name: | Sucla2_1 | ||||||||
Description: | succinate-CoA ligase ADP-forming beta subunit | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1309397 | AgrOrtholog |
BioCyc Gene | G2FUF-13159 | BioCyc |
BioCyc Pathway | PWY-5690 [TCA cycle II (plants and fungi)] | BioCyc |
BioCyc Pathway Image | PWY-5690 | BioCyc |
Ensembl Genes | ENSRNOG00000017481 | Ensembl, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000065195.4 | UniProtKB/TrEMBL |
ENSRNOT00000094835.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.30.1490.20 | UniProtKB/TrEMBL |
3.40.50.261 | UniProtKB/TrEMBL | |
ATP-grasp fold, B domain | UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7126990 | IMAGE-MGC_LOAD |
InterPro | ATP-grasp | UniProtKB/TrEMBL |
ATP-grasp_succ-CoA_synth-type | UniProtKB/TrEMBL | |
ATP_grasp_subdomain_1 | UniProtKB/TrEMBL | |
CoA_ligase | UniProtKB/TrEMBL | |
Succ-CoA_synthase_bsu_CS | UniProtKB/TrEMBL | |
Succ_CoA_betaA_euk | UniProtKB/TrEMBL | |
Succ_CoA_synthase_bsu | UniProtKB/TrEMBL | |
Succinyl-CoA_synth-like | UniProtKB/TrEMBL | |
KEGG Report | rno:361071 | UniProtKB/TrEMBL |
MGC_CLONE | MGC:189157 | IMAGE-MGC_LOAD |
NCBI Gene | 361071 | ENTREZGENE |
PANTHER | CoA_lig_beta | UniProtKB/TrEMBL |
SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL | UniProtKB/TrEMBL | |
Pfam | ATP-grasp_2 | UniProtKB/TrEMBL |
Ligase_CoA | UniProtKB/TrEMBL | |
PhenoGen | Sucla2 | PhenoGen |
PIRSF | SucCS_beta | UniProtKB/TrEMBL |
PROSITE | ATP_GRASP | UniProtKB/TrEMBL |
SUCCINYL_COA_LIG_3 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000017481 | RatGTEx |
Superfamily-SCOP | CoA_ligase | UniProtKB/TrEMBL |
Glutathione synthetase ATP-binding domain-like | UniProtKB/TrEMBL | |
UniProt | A0A8I6A1U8_RAT | UniProtKB/TrEMBL |
B2RZ24 | ENTREZGENE, UniProtKB/TrEMBL | |
F1LM47 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2019-12-06 | Sucla2 | succinate-CoA ligase ADP-forming subunit beta | Sucla2 | succinate-CoA ligase ADP-forming beta subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2016-05-05 | Sucla2 | succinate-CoA ligase ADP-forming beta subunit | Sucla2 | succinate-CoA ligase beta subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2016-04-13 | Sucla2 | succinate-CoA ligase beta subunit | Sucla2 | succinate-CoA ligase, ADP-forming, beta subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-10-23 | Sucla2 | succinate-CoA ligase, ADP-forming, beta subunit | Sucla2 | succinate-Coenzyme A ligase, ADP-forming, beta subunit | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Sucla2 | succinate-Coenzyme A ligase, ADP-forming, beta subunit | Sucla2_predicted | succinate-Coenzyme A ligase, ADP-forming, beta subunit (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2005-01-12 | Sucla2_predicted | succinate-Coenzyme A ligase, ADP-forming, beta subunit (predicted) | Symbol and Name status set to approved | 70820 | APPROVED |