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Gene: Col4a3 (collagen type IV alpha 3 chain) Rattus norvegicus
Symbol: Col4a3
Name: collagen type IV alpha 3 chain
RGD ID: 71085
Description: Predicted to have extracellular matrix structural constituent and integrin binding activity. Involved in response to glucose. Predicted to localize to collagen type IV trimer; endoplasmic reticulum; and extracellular space. Used to study glomerulonephritis. Human ortholog(s) of this gene implicated in Alport syndrome; autosomal dominant Alport syndrome; autosomal recessive Alport syndrome; benign familial hematuria; and end stage renal disease. Orthologous to human COL4A3 (collagen type IV alpha 3 chain); PARTICIPATES IN syndecan signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: collagen alpha-3(IV) chain; collagen type IV alpha 3 (Goodpasture antigen); collagen, type IV, alpha 3; collagen, type IV, alpha 3 (Goodpasture antigen); LOC363265; procollagen, type IV, alpha 3; similar to procollagen, type IV, alpha 3
Homo sapiens (human) : COL4A3 (collagen type IV alpha 3 chain)  HGNC  Alliance
Mus musculus (house mouse) : Col4a3 (collagen, type IV, alpha 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col4a3 (collagen type IV alpha 3 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL4A3 (collagen type IV alpha 3 chain)
Canis lupus familiaris (dog) : COL4A3 (collagen type IV alpha 3 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col4a3 (collagen type IV alpha 3 chain)
Sus scrofa (pig) : COL4A3 (collagen type IV alpha 3 chain)
Chlorocebus sabaeus (African green monkey) : COL4A3 (collagen type IV alpha 3 chain)
Heterocephalus glaber (naked mole-rat) : Col4a3 (collagen type IV alpha 3 chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0988,357,528 - 88,484,735 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl988,357,556 - 88,485,830 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0988,104,667 - 88,233,491 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4981,910,656 - 82,036,998 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1982,217,087 - 82,220,407 (+)NCBI
Celera981,318,911 - 81,443,381 (+)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Col4a3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 71085
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.