Eprs1 (glutamyl-prolyl-tRNA synthetase 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Eprs1 (glutamyl-prolyl-tRNA synthetase 1) Rattus norvegicus
Analyze
Symbol: Eprs1 (Ensembl: Eprs)
Name: glutamyl-prolyl-tRNA synthetase 1 (Ensembl:glutamyl-prolyl-tRNA synthetase)
RGD ID: 1310952
Description: Predicted to enable several functions, including RNA stem-loop binding activity; proline-tRNA ligase activity; and protein homodimerization activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; prolyl-tRNA aminoacylation; and regulation of long-chain fatty acid import into cell. Predicted to act upstream of or within cellular response to type II interferon. Predicted to be located in cytosol and plasma membrane. Predicted to be part of GAIT complex; aminoacyl-tRNA synthetase multienzyme complex; and ribonucleoprotein complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human EPRS1 (glutamyl-prolyl-tRNA synthetase 1); PARTICIPATES IN AGAT deficiency pathway; arginine and proline metabolic pathway; guanidinoacetate methyltransferase deficiency pathway; INTERACTS WITH (S)-colchicine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: bifunctional aminoacyl-tRNA synthetase; bifunctional glutamate/proline--tRNA ligase; Eprs; glutamyl-prolyl-tRNA synthetase; LOC108351325; LOC289352; proline--tRNA ligase-like
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21396,901,548 - 96,971,966 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,901,575 - 96,971,966 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,400,886 - 99,471,298 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.013100,806,806 - 100,876,877 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01397,983,145 - 98,053,557 (+)NCBIRnor_WKY
Rnor_6.013103,300,911 - 103,371,651 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,300,932 - 103,371,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,973,665 - 108,044,298 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413101,375,656 - 101,448,175 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113101,564,698 - 101,637,217 (+)NCBI
Celera1396,415,061 - 96,484,921 (+)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-amphetamine  (ISO)
(S)-colchicine  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-chloropropane-1,2-diol  (EXP)
5-fluorouracil  (ISO)
acetamide  (EXP)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
chlordecone  (ISO)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chloroprene  (EXP)
chlorpyrifos  (EXP,ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
clodronic acid  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (EXP,ISO)
dioxygen  (ISO)
diuron  (EXP)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenofibrate  (EXP,ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
geldanamycin  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
hydralazine  (ISO)
hydrogen peroxide  (ISO)
hydrogen sulfide  (ISO)
ibuprofen  (ISO)
ivermectin  (ISO)
L-ascorbic acid  (ISO)
lead diacetate  (EXP)
levonorgestrel  (ISO)
menadione  (ISO)
metformin  (EXP)
methapyrilene  (EXP)
methidathion  (ISO)
methotrexate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nefazodone  (EXP)
nimesulide  (EXP)
ochratoxin A  (ISO)
oxaliplatin  (EXP)
p-toluidine  (EXP)
paraquat  (EXP)
perfluorononanoic acid  (ISO)
phenobarbital  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
testosterone enanthate  (ISO)
testosterone undecanoate  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thimerosal  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
triphenyl phosphate  (EXP)
triptonide  (ISO)
trovafloxacin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
valproic acid  (ISO)
vincaleukoblastine  (EXP)
vinclozolin  (EXP)
vincristine  (EXP)
vorinostat  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
6. GOA pipeline RGD automated data pipeline
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10791971   PMID:12060739   PMID:12477932   PMID:15479637   PMID:19131329   PMID:19289464   PMID:19946888   PMID:22082260   PMID:23071094   PMID:23263184   PMID:24100331   PMID:24337748  
PMID:28178239  


Genomics

Comparative Map Data
Eprs1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21396,901,548 - 96,971,966 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1396,901,575 - 96,971,966 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1399,400,886 - 99,471,298 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.013100,806,806 - 100,876,877 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01397,983,145 - 98,053,557 (+)NCBIRnor_WKY
Rnor_6.013103,300,911 - 103,371,651 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13103,300,932 - 103,371,577 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013107,973,665 - 108,044,298 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413101,375,656 - 101,448,175 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113101,564,698 - 101,637,217 (+)NCBI
Celera1396,415,061 - 96,484,921 (+)NCBICelera
Cytogenetic Map13q26NCBI
EPRS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381219,968,600 - 220,046,505 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1219,968,600 - 220,046,530 (-)EnsemblGRCh38hg38GRCh38
GRCh371220,141,942 - 220,219,847 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361218,208,565 - 218,286,623 (-)NCBINCBI36Build 36hg18NCBI36
Build 341216,530,337 - 216,596,723NCBI
Celera1193,361,173 - 193,439,298 (-)NCBICelera
Cytogenetic Map1q41NCBI
HuRef1190,816,669 - 190,894,723 (-)NCBIHuRef
CHM1_11221,414,886 - 221,492,894 (-)NCBICHM1_1
T2T-CHM13v2.01219,207,867 - 219,285,874 (-)NCBIT2T-CHM13v2.0
Eprs
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391185,093,614 - 185,160,557 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1185,095,241 - 185,160,557 (+)EnsemblGRCm39 Ensembl
GRCm381185,361,417 - 185,428,360 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1185,363,044 - 185,428,360 (+)EnsemblGRCm38mm10GRCm38
MGSCv371187,186,974 - 187,252,234 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361187,063,883 - 187,129,143 (+)NCBIMGSCv36mm8
MGSCv361186,479,177 - 186,544,604 (+)NCBIMGSCv36mm8
Celera1192,317,193 - 192,381,950 (+)NCBICelera
Cytogenetic Map1H5NCBI
Eprs1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555203,550,558 - 3,606,697 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555203,550,558 - 3,606,015 (+)NCBIChiLan1.0ChiLan1.0
EPRS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11200,575,257 - 200,655,958 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1200,575,259 - 200,656,197 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01195,537,319 - 195,618,257 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
EPRS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13814,754,628 - 14,823,626 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3814,754,632 - 14,823,621 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3814,797,419 - 14,866,312 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03814,791,854 - 14,860,285 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3814,791,858 - 14,856,528 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13814,800,874 - 14,869,666 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03815,145,457 - 15,214,419 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03815,435,096 - 15,504,056 (-)NCBIUU_Cfam_GSD_1.0
Eprs1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934456,897,415 - 56,971,602 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366502,145,607 - 2,220,019 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366502,145,614 - 2,219,812 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPRS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl109,579,304 - 9,648,414 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1109,579,301 - 9,648,416 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21011,663,038 - 11,730,358 (-)NCBISscrofa10.2Sscrofa10.2susScr3
EPRS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1259,534,747 - 9,618,119 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl259,534,114 - 9,618,141 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660559,840,725 - 9,924,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eprs1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248353,635,457 - 3,695,909 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248353,635,829 - 3,695,875 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Eprs1
197 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:61
Interacting mature miRNAs:61
Transcripts:ENSRNOT00000038264
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1330395351101056920Rat
1641901Alcrsp6Alcohol response QTL 6response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)135236217197362171Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1356056920101056920Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137402391897213863Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1374862117101339893Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat

Markers in Region
RH142520  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21396,953,292 - 96,953,555 (+)MAPPERmRatBN7.2
Rnor_6.013103,352,979 - 103,353,241NCBIRnor6.0
Rnor_5.013108,025,626 - 108,025,888UniSTSRnor5.0
RGSC_v3.413101,429,697 - 101,429,959UniSTSRGSC3.4
Celera1396,466,443 - 96,466,705UniSTS
RH 3.4 Map13656.8UniSTS
Cytogenetic Map13q26UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000038264   ⟹   ENSRNOP00000033323
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,901,703 - 96,971,966 (+)Ensembl
Rnor_6.0 Ensembl13103,301,074 - 103,371,457 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085214   ⟹   ENSRNOP00000071057
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,901,575 - 96,971,966 (+)Ensembl
Rnor_6.0 Ensembl13103,300,932 - 103,371,577 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101144   ⟹   ENSRNOP00000083045
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,901,703 - 96,971,966 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105669   ⟹   ENSRNOP00000083815
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,905,045 - 96,971,966 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000116204   ⟹   ENSRNOP00000090936
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1396,901,575 - 96,971,966 (+)Ensembl
RefSeq Acc Id: NM_001024238   ⟹   NP_001019409
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,901,703 - 96,971,772 (+)NCBI
Rnor_6.013103,301,074 - 103,371,457 (+)NCBI
Rnor_5.013107,973,665 - 108,044,298 (+)NCBI
RGSC_v3.413101,375,656 - 101,448,175 (+)RGD
Celera1396,415,061 - 96,484,921 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250425   ⟹   XP_006250487
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,901,548 - 96,971,966 (+)NCBI
Rnor_6.013103,300,911 - 103,371,651 (+)NCBI
Rnor_5.013107,973,665 - 108,044,298 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250426   ⟹   XP_006250488
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,901,548 - 96,971,966 (+)NCBI
Rnor_6.013103,300,912 - 103,371,651 (+)NCBI
Rnor_5.013107,973,665 - 108,044,298 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039090582   ⟹   XP_038946510
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21396,901,552 - 96,971,966 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001019409   ⟸   NM_001024238
- UniProtKB: Q6TXE9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250487   ⟸   XM_006250425
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GJ92 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250488   ⟸   XM_006250426
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JZI2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000071057   ⟸   ENSRNOT00000085214
RefSeq Acc Id: ENSRNOP00000033323   ⟸   ENSRNOT00000038264
RefSeq Acc Id: XP_038946510   ⟸   XM_039090582
- Peptide Label: isoform X3
RefSeq Acc Id: ENSRNOP00000083815   ⟸   ENSRNOT00000105669
RefSeq Acc Id: ENSRNOP00000090936   ⟸   ENSRNOT00000116204
RefSeq Acc Id: ENSRNOP00000083045   ⟸   ENSRNOT00000101144
Protein Domains
AA_TRNA_LIGASE_II   WHEP-TRS

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JZI2-F1-model_v2 AlphaFold A0A0G2JZI2 1-1512 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699099
Promoter ID:EPDNEW_R9617
Type:initiation region
Name:Eprs_1
Description:glutamyl-prolyl-tRNA synthetase
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.013103,300,951 - 103,301,011EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310952 AgrOrtholog
BioCyc Gene G2FUF-16979 BioCyc
BioCyc Pathway TRNA-CHARGING-PWY [tRNA charging] BioCyc
Ensembl Genes ENSRNOG00000002393 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000033323 ENTREZGENE
  ENSRNOP00000033323.4 UniProtKB/TrEMBL
  ENSRNOP00000071057 ENTREZGENE
  ENSRNOP00000071057.2 UniProtKB/TrEMBL
  ENSRNOP00000083045.1 UniProtKB/TrEMBL
  ENSRNOP00000083815.1 UniProtKB/TrEMBL
  ENSRNOP00000090936 ENTREZGENE
  ENSRNOP00000090936.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000038264 ENTREZGENE
  ENSRNOT00000038264.5 UniProtKB/TrEMBL
  ENSRNOT00000085214 ENTREZGENE
  ENSRNOT00000085214.2 UniProtKB/TrEMBL
  ENSRNOT00000101144.1 UniProtKB/TrEMBL
  ENSRNOT00000105669.1 UniProtKB/TrEMBL
  ENSRNOT00000116204 ENTREZGENE
  ENSRNOT00000116204.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.1160.10 UniProtKB/TrEMBL
  2.40.240.10 UniProtKB/TrEMBL
  3.30.110.30 UniProtKB/TrEMBL
  3.30.930.10 UniProtKB/TrEMBL
  3.40.50.620 UniProtKB/TrEMBL
  3.40.50.800 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7364865 IMAGE-MGC_LOAD
InterPro aa-tRNA-synt_IIb_cons-dom UniProtKB/TrEMBL
  aa-tRNA-synth_I_CS UniProtKB/TrEMBL
  aa-tRNA-synth_II/BPL/LPL UniProtKB/TrEMBL
  Aminoacyl-tRNA-synth_II UniProtKB/TrEMBL
  Anticodon-bd UniProtKB/TrEMBL
  Anticodon-bd_dom_sf UniProtKB/TrEMBL
  Glu-tRNA-synth_arc/euk UniProtKB/TrEMBL
  Glu/Gln-tRNA-synth_Ib_cat-dom UniProtKB/TrEMBL
  Glu/Gln-tRNA-synth_Ib_codon-bd UniProtKB/TrEMBL
  Glu/Gln-tRNA-synth_Ic UniProtKB/TrEMBL
  Glu_tRNA_lig_a-bdl UniProtKB/TrEMBL
  Glutathione-S-Trfase_C_sf UniProtKB/TrEMBL
  Pro-tRNA-synth_IIa_arc-type UniProtKB/TrEMBL
  Pro-tRNA_synth_II UniProtKB/TrEMBL
  Pro-tRNA_synth_II_C UniProtKB/TrEMBL
  ProRS_core_arch_euk UniProtKB/TrEMBL
  Rbsml_L25/Gln-tRNA_synth_b-brl UniProtKB/TrEMBL
  Ribosomal_L25/Gln-tRNA_synth UniProtKB/TrEMBL
  Rossmann-like_a/b/a_fold UniProtKB/TrEMBL
  S15_NS1_RNA-bd UniProtKB/TrEMBL
  WHEP-TRS UniProtKB/TrEMBL
KEGG Report rno:289352 UniProtKB/TrEMBL
MGC_CLONE MGC:109566 IMAGE-MGC_LOAD
NCBI Gene 289352 ENTREZGENE
PANTHER PTHR43382 UniProtKB/TrEMBL
Pfam HGTP_anticodon UniProtKB/TrEMBL
  ProRS-C_1 UniProtKB/TrEMBL
  tRNA-synt_1c UniProtKB/TrEMBL
  tRNA-synt_1c_C UniProtKB/TrEMBL
  tRNA-synt_2b UniProtKB/TrEMBL
  WHEP-TRS UniProtKB/TrEMBL
PhenoGen Eprs1 PhenoGen
PRINTS TRNASYNTHGLU UniProtKB/TrEMBL
PROSITE AA_TRNA_LIGASE_I UniProtKB/TrEMBL
  AA_TRNA_LIGASE_II UniProtKB/TrEMBL
  WHEP_TRS_1 UniProtKB/TrEMBL
  WHEP_TRS_2 UniProtKB/TrEMBL
SMART ProRS-C_1 UniProtKB/TrEMBL
  WHEP-TRS UniProtKB/TrEMBL
Superfamily-SCOP GST_C_like UniProtKB/TrEMBL
  Pro-tRNA_synth_II_C UniProtKB/TrEMBL
  Ribosomal_L25rel UniProtKB/TrEMBL
  S15/NS1_bind UniProtKB/TrEMBL
  SSF55681 UniProtKB/TrEMBL
TIGRFAMs gltX_arch UniProtKB/TrEMBL
  ProS_fam_I UniProtKB/TrEMBL
UniProt A0A0G2JZI2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZY25_RAT UniProtKB/TrEMBL
  A0A8I6G8C4_RAT UniProtKB/TrEMBL
  A0A8I6GJ92 ENTREZGENE, UniProtKB/TrEMBL
  Q6TXE9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-10-13 Eprs1  glutamyl-prolyl-tRNA synthetase 1  Eprs  glutamyl-prolyl-tRNA synthetase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Eprs  glutamyl-prolyl-tRNA synthetase  LOC108351325  proline--tRNA ligase-like  Data Merged 737654 PROVISIONAL
2016-08-02 LOC108351325  proline--tRNA ligase-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-12-06 Eprs  glutamyl-prolyl-tRNA synthetase  Eprs_predicted  glutamyl-prolyl-tRNA synthetase (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Eprs_predicted  glutamyl-prolyl-tRNA synthetase (predicted)      Symbol and Name status set to approved 70820 APPROVED